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Diffstat (limited to 'print_nlmixr_saem_biphasic_tc.txt')
| -rw-r--r-- | print_nlmixr_saem_biphasic_tc.txt | 39 |
1 files changed, 39 insertions, 0 deletions
diff --git a/print_nlmixr_saem_biphasic_tc.txt b/print_nlmixr_saem_biphasic_tc.txt new file mode 100644 index 00000000..ad59005d --- /dev/null +++ b/print_nlmixr_saem_biphasic_tc.txt @@ -0,0 +1,39 @@ +Kinetic nonlinear mixed-effects model fit by saem using nlmixr +Structural model: +d_parent/dt = - ((k1 * g * exp(-k1 * time) + k2 * (1 - g) * exp(-k2 * + time)) / (g * exp(-k1 * time) + (1 - g) * exp(-k2 * time))) + * parent +d_m1/dt = + f_parent_to_m1 * ((k1 * g * exp(-k1 * time) + k2 * (1 - g) + * exp(-k2 * time)) / (g * exp(-k1 * time) + (1 - g) * + exp(-k2 * time))) * parent - k_m1 * m1 + +Data: +507 observations of 2 variable(s) grouped in 15 datasets + +Likelihood: + AIC BIC logLik + 2400 2468 -1184 + +Fitted parameters: + Est. SE %RSE Back-transformed(95%CI) BSV(CV% or SD) +parent_0 100 0.685 0.682 100 (99, 102) 0.278 +log_k_m1 -5.35 0.0812 1.52 0.00477 (0.00407, 0.00559) 13.7 +f_parent_qlogis -0.091 0.096 106 0.477 (0.431, 0.524) 0.320 +log_k1 -2.76 0.0969 3.5 0.063 (0.0521, 0.0762) 29.9 +log_k2 -4.49 0.0658 1.47 0.0113 (0.00991, 0.0128) 18.6 +g_qlogis -0.167 0.142 85.3 0.458 (0.39, 0.528) 0.339 +sigma_low_parent 1.04 1.04 +rsd_high_parent 0.0531 0.0531 +sigma_low_m1 0.819 0.819 +rsd_high_m1 0.058 0.058 + Shrink(SD)% +parent_0 87.7%> +log_k_m1 44.8%> +f_parent_qlogis -0.375%> +log_k1 6.76%< +log_k2 10.4%< +g_qlogis 20.3%= +sigma_low_parent +rsd_high_parent +sigma_low_m1 +rsd_high_m1 |