From 7035cde3a53781721fe15a8893fdf328c789bdd2 Mon Sep 17 00:00:00 2001 From: Johannes Ranke Date: Mon, 7 Mar 2022 12:03:40 +0100 Subject: Remove nlmixr interface for release of mkin 1.1.0 I am postponing my attempts to get the nlmixr interface to CRAN, given some problems with nlmixr using R-devel under Windows, see https://github.com/nlmixrdevelopment/nlmixr/issues/596 and https://github.com/r-hub/rhub/issues/512, which is fixed by the removal of nlmixr from the testsuite. For the tests to be more platform independent, the biphasic mixed effects models test dataset was defined in a way that fitting should be more robust (less ill-defined). --- NEWS.md | 4 +--- 1 file changed, 1 insertion(+), 3 deletions(-) (limited to 'NEWS.md') diff --git a/NEWS.md b/NEWS.md index 61d81f20..944e4df1 100644 --- a/NEWS.md +++ b/NEWS.md @@ -2,8 +2,6 @@ ## Mixed-effects models -- Introduce an interface to nlmixr, supporting estimation methods 'saem' and 'focei': S3 method 'nlmixr.mmkin' using the helper functions 'nlmixr_model' and 'nlmixr_data' to set up nlmixr models for mmkin row objects, with summary and plot methods. - - Reintroduce the interface to saemix (now on CRAN), in particular the generic function 'saem' with a generator 'saem.mmkin', currently using 'saemix_model' and 'saemix_data', summary and plot methods - 'mean_degparms': New argument 'test_log_parms' that makes the function only consider log-transformed parameters where the untransformed parameters pass the t-test for a certain confidence level. This can be used to obtain more plausible starting parameters for the different mixed-effects model backends @@ -12,7 +10,7 @@ - 'vignettes/web_only/dimethenamid_2018.rmd': Example evaluations of the dimethenamid data. -- 'intervals': Provide methods of this nlme function for 'nlmixr.mmkin' and 'saem.mmkin' objects. +- 'intervals': Provide a method of this nlme function for 'saem.mmkin' objects. # mkin 1.0.5 (2021-09-15) -- cgit v1.2.1