ℹ Testing mkin
✔ | F W S  OK | Context
✔ |         5 | AIC calculation
✔ |         5 | Analytical solutions for coupled models [1.5s]
✔ |         5 | Calculation of Akaike weights
✔ |         3 | Export dataset for reading into CAKE
✔ |         6 | Use of precompiled symbols in mkinpredict [3.1s]
✔ |        12 | Confidence intervals and p-values [0.4s]
✔ |     1  12 | Dimethenamid data from 2018 [12.9s]
────────────────────────────────────────────────────────────────────────────────
Skip ('test_dmta.R:88:3'): Different backends get consistent results for SFO-SFO3+, dimethenamid data
Reason: Fitting this ODE model with saemix takes about 5 minutes on my new system
────────────────────────────────────────────────────────────────────────────────
✔ |        14 | Error model fitting [2.3s]
✔ |         5 | Time step normalisation
✔ |         4 | Calculation of FOCUS chi2 error levels [0.3s]
✔ |        14 | Results for FOCUS D established in expertise for UBA (Ranke 2014) [0.4s]
✔ |         4 | Test fitting the decline of metabolites from their maximum [0.2s]
✔ |         1 | Fitting the logistic model [0.1s]
✔ |        10 | Batch fitting and diagnosing hierarchical kinetic models [19.0s]
✔ |     2  16 | Nonlinear mixed-effects models [148.3s]
────────────────────────────────────────────────────────────────────────────────
Skip ('test_mixed.R:80:3'): saemix results are reproducible for biphasic fits
Reason: Fitting with saemix takes around 10 minutes when using deSolve

Skip ('test_mixed.R:133:3'): SFO-SFO saemix specific analytical solution work
Reason: This is seldom used, so save some time
────────────────────────────────────────────────────────────────────────────────
✔ |         3 | Test dataset classes mkinds and mkindsg
✔ |        10 | Special cases of mkinfit calls [0.3s]
✔ |         3 | mkinfit features [0.5s]
✔ |         8 | mkinmod model generation and printing
✔ |         3 | Model predictions with mkinpredict [0.1s]
✖ | 3       9 | Multistart method for saem.mmkin models [22.9s]
────────────────────────────────────────────────────────────────────────────────
Failure ('test_multistart.R:44:3'): multistart works for saem.mmkin models
Snapshot of `testcase` to 'multistart/mixed-model-fit-for-saem-object-with-mkin-transformations.svg' has changed
Run `testthat::snapshot_review('multistart/')` to review changes
Backtrace:
 1. vdiffr::expect_doppelganger(...)
      at test_multistart.R:44:2
 3. testthat::expect_snapshot_file(...)

Failure ('test_multistart.R:55:3'): multistart works for saem.mmkin models
Snapshot of `testcase` to 'multistart/llhist-for-dfop-sfo-fit.svg' has changed
Run `testthat::snapshot_review('multistart/')` to review changes
Backtrace:
 1. vdiffr::expect_doppelganger("llhist for dfop sfo fit", llhist_dfop_sfo)
      at test_multistart.R:55:2
 3. testthat::expect_snapshot_file(...)

Failure ('test_multistart.R:56:3'): multistart works for saem.mmkin models
Snapshot of `testcase` to 'multistart/parplot-for-dfop-sfo-fit.svg' has changed
Run `testthat::snapshot_review('multistart/')` to review changes
Backtrace:
 1. vdiffr::expect_doppelganger("parplot for dfop sfo fit", parplot_dfop_sfo)
      at test_multistart.R:56:2
 3. testthat::expect_snapshot_file(...)
────────────────────────────────────────────────────────────────────────────────
✔ |        16 | Evaluations according to 2015 NAFTA guidance [1.5s]
✔ |         9 | Nonlinear mixed-effects models with nlme [3.7s]
✖ | 1      14 | Plotting [4.6s]
────────────────────────────────────────────────────────────────────────────────
Failure ('test_plot.R:55:3'): Plotting mkinfit, mmkin and mixed model objects is reproducible
Snapshot of `testcase` to 'plot/mixed-model-fit-for-nlme-object.svg' has changed
Run `testthat::snapshot_review('plot/')` to review changes
Backtrace:
 1. vdiffr::expect_doppelganger(...)
      at test_plot.R:55:2
 3. testthat::expect_snapshot_file(...)
────────────────────────────────────────────────────────────────────────────────
✔ |         4 | Residuals extracted from mkinfit models
✔ |     1  36 | saemix parent models [31.2s]
────────────────────────────────────────────────────────────────────────────────
Skip ('test_saemix_parent.R:143:3'): We can also use mkin solution methods for saem
Reason: This still takes almost 2.5 minutes although we do not solve ODEs
────────────────────────────────────────────────────────────────────────────────
✔ |         2 | Complex test case from Schaefer et al. (2007) Piacenza paper [0.5s]
✔ |        11 | Processing of residue series
✔ |        10 | Fitting the SFORB model [1.7s]
✔ |         1 | Summaries of old mkinfit objects
✔ |         5 | Summary
✔ |         4 | Results for synthetic data established in expertise for UBA (Ranke 2014) [0.8s]
✔ |         9 | Hypothesis tests [2.9s]
✔ |         4 | Calculation of maximum time weighted average concentrations (TWAs) [0.7s]

══ Results ═════════════════════════════════════════════════════════════════════
Duration: 260.5 s

── Skipped tests  ──────────────────────────────────────────────────────────────
• Fitting this ODE model with saemix takes about 5 minutes on my new system (1)
• Fitting with saemix takes around 10 minutes when using deSolve (1)
• This is seldom used, so save some time (1)
• This still takes almost 2.5 minutes although we do not solve ODEs (1)

[ FAIL 4 | WARN 0 | SKIP 4 | PASS 277 ]