From 699448335d6fc5668b569577cb38a628c258eaec Mon Sep 17 00:00:00 2001 From: ranke Date: Wed, 21 Dec 2005 15:33:22 +0000 Subject: Changed the terminology from EC50 to ED50 reflecting that the package is meant for dose-response analysis in general and not only for concentration-response analysis. This is the first revision that has been prepared with the knowledge of the existence of the drc package for dose-response curve analysis. git-svn-id: http://kriemhild.uft.uni-bremen.de/svn/drfit@48 d1b72e20-2ee0-0310-a1c4-ad5adbbefcdc --- chm/drfit.html | 99 ---------------------------------------------------------- 1 file changed, 99 deletions(-) delete mode 100644 chm/drfit.html (limited to 'chm/drfit.html') diff --git a/chm/drfit.html b/chm/drfit.html deleted file mode 100644 index 23dd70f..0000000 --- a/chm/drfit.html +++ /dev/null @@ -1,99 +0,0 @@ -Fit dose-response models - - - - -
drfit(drfit)R Documentation
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Fit dose-response models

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Description

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-Fit dose-response relationships to dose-response data and calculate -biometric results for (eco)toxicity evaluation -

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Usage

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-  drfit(data, startlogEC50 = NA, lognorm = TRUE, logis = FALSE, 
-    linearlogis = FALSE, b0 = 2, f0 = 0)
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Arguments

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data -A data frame as returned from drdata. The data frame has to -contain at least a factor called "substance", a vector called "unit" -containing the unit used for the dose, a column "response" with the -response values of the test system normalized between 0 and 1 and a column -"dose" with the numeric dose values. For later use of the -drplot function, a factor called "dosefactor" also has to be -present, containing the dose as a factor. -
startlogEC50 -Especially for the linearlogis model, a suitable log10 of the EC50 has to be given -by the user, since it is not correctly estimated for data showing hormesis with -the default estimation method.
lognorm -A boolean defining if cumulative density curves of normal distributions -are fitted to the data. Default ist TRUE.
logis -A boolean defining if cumulative densitiy curves of logistic distributions -are fitted to the data. Default is FALSE.
linearlogis -A boolean defining if the linear-logistic function as defined by van Ewijk and Hoekstra -1993 is fitted to the data. Default is FALSE.
b0,f0 -If the linearlogistic model is fitted, b0 and f0 give the possibility to -adapt the starting values for the parameters b and f.
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Value

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results -A data frame containing at least one line for each substance. If the data did not -show a mean response < 0.5 at the highest dose level, the modeltype is set to "none". -Every successful fit is reported in one line. Parameters of the fitted curves are only -reported if the fitted EC50 is not higher than the highest dose.
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Author(s)

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-Johannes Ranke -jranke@uni-bremen.de -http://www.uft.uni-bremen.de/chemie/ranke -

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Examples

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-data(antifoul)
-r <- drfit(antifoul)
-format(r,digits=2)
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[Package Contents]
- - -- cgit v1.2.1