From 8154a03c79eb910c42dcff03fd8fa611cdc8cc9d Mon Sep 17 00:00:00 2001
From: "(no author)" <(no author)@d1b72e20-2ee0-0310-a1c4-ad5adbbefcdc>
Date: Tue, 27 Jul 2004 07:36:01 +0000
Subject: First version published on CRAN

git-svn-id: http://kriemhild.uft.uni-bremen.de/svn/drfit@1 d1b72e20-2ee0-0310-a1c4-ad5adbbefcdc
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+\name{drfit}
+\alias{drfit}
+\title{Fit dose-response models}
+\description{
+	Fit dose-response relationships to dose-response data and calculate
+  biometric results for (eco)toxicity evaluation
+}
+\usage{
+  drfit(data, startlogEC50 = NA, lognorm = TRUE, logis = FALSE, 
+    linearlogis = FALSE, b0 = 2, f0 = 0)
+}
+\arguments{
+  \item{data}{
+    A data frame as returned from \code{\link{drdata}}.  The data frame has to
+    contain at least a factor called "substance", a vector called "unit"
+    containing the unit used for the dose, a column "response" with the
+    response values of the test system normalized between 0 and 1 and a column
+    "dose" with the numeric dose values. For later use of the
+    \code{\link{drplot}} function, a factor called "dosefactor" also has to be
+    present, containing the dose as a factor.
+    }
+  \item{startlogEC50}{
+    Especially for the linearlogis model, a suitable log10 of the EC50 has to be given 
+    by the user, since it is not correctly estimated for data showing hormesis with
+    the default estimation method.}
+  \item{lognorm}{
+    A boolean defining if cumulative density curves of normal distributions
+    are fitted to the data. Default ist TRUE.} 
+  \item{logis}{
+    A boolean defining if cumulative densitiy curves of logistic distributions
+    are fitted to the data. Default is FALSE.} 
+  \item{linearlogis}{
+    A boolean defining if the linear-logistic function as defined by van Ewijk and Hoekstra
+    1993 is fitted to the data. Default is FALSE.}
+  \item{b0,f0}{
+    If the linearlogistic model is fitted, b0 and f0 give the possibility to
+    adapt the starting values for the parameters b and f.}
+}
+\value{
+  \item{results}{
+      A data frame containing at least one line for each substance. If the data did not
+      show a mean response < 0.5 at the highest dose level, the modeltype is set to "none".
+      Every successful fit is reported in one line. Parameters of the fitted curves are only
+      reported if the fitted EC50 is not higher than the highest dose.}
+    
+} 
+\examples{
+\dontrun{data(antifoul)}
+\dontrun{r <- drfit(antifoul)}
+\dontrun{format(r,digits=2)}
+}
+\author{
+  Johannes Ranke 
+  \email{jranke@uni-bremen.de} 
+  \url{http://www.uft.uni-bremen.de/chemie/ranke}
+}
+\keyword{models}
+\keyword{regression}
+\keyword{nonlinear}
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