IM1xIPC81.RdThis is the raw data documenting the influence of the alkyl chain length in 3 position on the toxicity to the promyelocytic leukemia rat cell line IPC-81. The substances are named according to the UFT naming scheme of these substances. IM13 BF4 means 1-methyl-3-propylimidazolium tetrafluoroborate, IM14 BF4 means 1-methyl-3-butylimidazolium tetrafluoroborate and IM1-10 BF4 means 1-methyl-3-decylimidazolium tetrafluoroborate. This is a subset (only the BF4 anion) of the data shown in Figure 3 in Ranke et al. (2004).
data(IM1xIPC81)
A dataframe containing the data as required for the
drfit function. An additional column contains
the tested organism (name of the cell line).
Ranke J, Mölter K, Stock F, Bottin-Weber U, Poczobutt J, Hoffmann J, Ondruschka B, Filser J, Jastorff B (2004) Biological effects of imidazolium ionic liquids with varying chain lenghts in acute Vibrio fischeri and WST-1 cell viability assays. Ecotoxicology and Environmental Safety 58(3) 396-404
rIM1xIPC81 <- drfit(IM1xIPC81, linlogit = TRUE, showED50 = TRUE, EDx = 10)#> #>#> #>#> Warning: NaNs wurden erzeugt#> #>#> #>#> #>#>#> Warning: NaNs wurden erzeugt#> #>#>#> Warning: NaNs wurden erzeugt#> #>#>#> Warning: NaNs wurden erzeugt#> #>#>rIM1xIPC81.drc <- drcfit(IM1xIPC81, linlogit = TRUE, showED50 = TRUE, EDx = 10)#> #>#> #>#> #>#> #>#> #>#> #>#> #>#> #>print(rIM1xIPC81,digits=4)#> Substance ndl n lld lhd mtype logED50 2.5% 97.5% unit sigma #> 1 IM13 BF4 9 81 0.5918 3.000 inactive NA NA NA microM NA #> 2 IM14 BF4 20 216 -0.0103 3.176 no fit NA NA NA microM NA #> 3 IM15 BF4 9 135 0.5918 3.000 inactive NA NA NA microM NA #> 4 IM16 BF4 9 108 0.5918 3.000 inactive NA NA NA microM NA #> 5 IM17 BF4 9 81 0.5918 3.000 linlogit 2.5786 2.506 2.6617 microM 0.2376 #> 6 IM18 BF4 9 135 0.5918 3.000 linlogit 1.6806 1.623 1.7419 microM 0.2325 #> 7 IM19 BF4 9 81 0.5918 3.000 linlogit 1.6496 1.598 1.7031 microM 0.1453 #> 8 IM1-10 BF4 11 162 -0.0103 3.000 linlogit 0.7697 0.687 0.8544 microM 0.2988 #> a b c ED50 ED50 2.5% ED50 97.5% EDx10 #> 1 NA NA NA NA NA NA NA #> 2 NA NA NA NA NA NA NA #> 3 NA NA NA NA NA NA NA #> 4 NA NA NA NA NA NA NA #> 5 2.5786 2.300 0.01468 378.941 320.424 458.918 230.782 #> 6 1.6806 2.237 0.05719 47.930 41.973 55.194 27.367 #> 7 1.6496 1.977 0.10956 44.628 39.671 50.483 23.031 #> 8 0.7697 1.936 0.45809 5.884 4.864 7.152 2.835print(rIM1xIPC81.drc,digits=4)#> Substance ndl n lld lhd mtype logED50 2.5% 97.5% unit sigma #> 1 IM13 BF4 9 81 0.5918 3.000 inactive NA NA NA microM NA #> 2 IM14 BF4 20 216 -0.0103 3.176 linlogit NA NA NA microM 0.1529 #> 3 IM15 BF4 9 135 0.5918 3.000 inactive NA NA NA microM NA #> 4 IM16 BF4 9 108 0.5918 3.000 inactive NA NA NA microM NA #> 5 IM17 BF4 9 81 0.5918 3.000 linlogit 2.5786 2.4935 2.6497 microM 0.2376 #> 6 IM18 BF4 9 135 0.5918 3.000 linlogit 1.6806 1.6168 1.7362 microM 0.2325 #> 7 IM19 BF4 9 81 0.5918 3.000 linlogit 1.6496 1.5940 1.6990 microM 0.1453 #> 8 IM1-10 BF4 11 162 -0.0103 3.000 linlogit 0.7697 0.6774 0.8458 microM 0.2988 #> a b c ED50 ED50 2.5% ED50 97.5% EDx10 EDx10 2.5% #> 1 NA NA NA NA NA NA NA NA #> 2 5.390e+15 0.3148 -0.0001736 NA NA NA NA NA #> 3 NA NA NA NA NA NA NA NA #> 4 NA NA NA NA NA NA NA NA #> 5 1.281e+02 2.3001 0.0146821 378.964 311.555 446.372 230.790 202.915 #> 6 2.079e+01 2.2373 0.0571925 47.930 41.382 54.478 27.367 23.809 #> 7 1.342e+01 1.9773 0.1094542 44.630 39.260 50.000 23.036 20.614 #> 8 2.258e+00 1.9362 0.4580784 5.884 4.758 7.011 2.835 2.181 #> EDx10 97.5% #> 1 NA #> 2 NA #> 3 NA #> 4 NA #> 5 258.665 #> 6 30.925 #> 7 25.459 #> 8 3.489