This is the raw data documenting the influence of the alkyl chain length in 3 position on the toxicity to the marine luminescent bacteria V. fischeri. The substances are named according to the UFT naming scheme of these substances. IM13 BF4 means 1-methyl-3-propylimidazolium tetrafluoroborate, IM14 BF4 means 1-methyl-3-butylimidazolium tetrafluoroborate and IM1-10 BF4 means 1-methyl-3-decylimidazolium tetrafluoroborate.
data(IM1xVibrio)
A dataframe containing the data as required for the drfit
function. Additional columns contain the species tested (luminescent bacteria
Vibrio fischeri, organism), and a field specifying if the data is
regarded valid (ok).
Ranke J, Mölter K, Stock F, Bottin-Weber U, Poczobutt J, Hoffmann J, Ondruschka B, Filser J, Jastorff B (2004) Biological effects of imidazolium ionic liquids with varying chain lenghts in acute Vibrio fischeri and WST-1 cell viability assays. Ecotoxicology and Environmental Safety 58(3) 396-404
rIM1xVibrio <- drfit(IM1xVibrio, logit = TRUE, chooseone = FALSE, showED50 = TRUE, EDx = c(10, 20))#> #>#>#>#> #>#>#>#> #>#>#>#> #>#>#>#> #>#>#>#> #>#>#>#> #>#>#>#> #>#>#>print(rIM1xVibrio, digits = 4)#> Substance ndl n lld lhd mtype logED50 2.5% 97.5% unit sigma #> 1 IM13 BF4 13 22 -5.301 4.699 probit 3.9399 3.8636 4.0160 microM 0.06303 #> 2 IM13 BF4 13 22 -5.301 4.699 logit 3.9461 3.8708 4.0211 microM 0.06188 #> 3 IM14 BF4 12 57 -4.301 4.699 probit 3.5442 3.5030 3.5855 microM 0.05905 #> 4 IM14 BF4 12 57 -4.301 4.699 logit 3.5465 3.5044 3.5885 microM 0.06030 #> 5 IM15 BF4 7 20 -0.301 4.699 probit 3.1398 3.1136 3.1662 microM 0.02695 #> 6 IM15 BF4 7 20 -0.301 4.699 logit 3.1387 3.1118 3.1659 microM 0.02723 #> 7 IM16 BF4 13 30 -4.301 4.699 probit 3.1804 3.1436 3.2176 microM 0.04514 #> 8 IM16 BF4 13 30 -4.301 4.699 logit 3.1814 3.1440 3.2190 microM 0.04553 #> 9 IM17 BF4 10 20 -1.301 4.699 probit 2.4317 2.3681 2.4951 microM 0.04773 #> 10 IM17 BF4 10 20 -1.301 4.699 logit 2.4353 2.3672 2.5026 microM 0.05050 #> 11 IM18 BF4 10 17 -2.301 2.699 probit 1.4015 1.3147 1.4881 microM 0.05611 #> 12 IM18 BF4 10 17 -2.301 2.699 logit 1.4051 1.3129 1.4966 microM 0.05898 #> 13 IM19 BF4 13 22 -5.301 2.699 probit 0.7158 0.6704 0.7592 microM 0.02956 #> 14 IM19 BF4 13 22 -5.301 2.699 logit 0.7172 0.6689 0.7635 microM 0.03210 #> 15 IM1-10 BF4 11 20 -6.301 2.699 probit -0.1790 -0.2569 -0.1037 microM 0.04099 #> 16 IM1-10 BF4 11 20 -6.301 2.699 logit -0.1831 -0.2620 -0.1055 microM 0.04192 #> a b ED50 ED50 2.5% ED50 97.5% EDx10 EDx20 #> 1 3.9399 0.5763 8707.8956 7305.0279 1.038e+04 1.590e+03 2850.222 #> 2 3.9461 0.3426 8832.9407 7426.2282 1.050e+04 1.561e+03 2959.147 #> 3 3.5442 0.6561 3501.1558 3184.3196 3.851e+03 5.051e+02 981.759 #> 4 3.5465 0.3911 3519.5779 3194.6808 3.877e+03 4.867e+02 1010.014 #> 5 3.1398 0.5527 1379.9037 1298.9533 1.466e+03 2.701e+02 472.823 #> 6 3.1387 0.3347 1376.4086 1293.7152 1.465e+03 2.532e+02 472.911 #> 7 3.1804 0.4882 1515.0421 1391.8150 1.650e+03 3.588e+02 588.292 #> 8 3.1814 0.2957 1518.4650 1393.2665 1.656e+03 3.401e+02 590.840 #> 9 2.4317 0.6387 270.2279 233.3814 3.127e+02 4.105e+01 78.382 #> 10 2.4353 0.3810 272.4409 232.9287 3.182e+02 3.965e+01 80.754 #> 11 1.4015 0.8009 25.2069 20.6383 3.077e+01 2.372e+00 5.340 #> 12 1.4051 0.4816 25.4135 20.5545 3.138e+01 2.222e+00 5.463 #> 13 0.7158 0.6969 5.1975 4.6814 5.744e+00 6.647e-01 1.347 #> 14 0.7172 0.4132 5.2141 4.6652 5.801e+00 6.446e-01 1.394 #> 15 -0.1790 0.8019 0.6622 0.5534 7.876e-01 6.212e-02 0.140 #> 16 -0.1831 0.4816 0.6560 0.5470 7.843e-01 5.738e-02 0.141rIM1xVibrio.drc <- drcfit(IM1xVibrio, logit = TRUE, chooseone = FALSE, showED50 = TRUE, EDx = c(10, 20))#> #>#> #>#> #>#> #>#> #>#> #>#> #>#> #>print(rIM1xVibrio.drc, digits = 4)#> Substance ndl n lld lhd mtype logED50 2.5% 97.5% unit sigma #> 1 IM13 BF4 13 22 -5.301 4.699 probit 3.9399 3.8563 4.0100 microM 0.06303 #> 2 IM13 BF4 13 22 -5.301 4.699 logit 3.9461 3.8637 4.0153 microM 0.06188 #> 3 IM14 BF4 12 57 -4.301 4.699 probit 3.5442 3.5009 3.5836 microM 0.05905 #> 4 IM14 BF4 12 57 -4.301 4.699 logit 3.5465 3.5023 3.5866 microM 0.06030 #> 5 IM15 BF4 7 20 -0.301 4.699 probit 3.1398 3.1127 3.1654 microM 0.02695 #> 6 IM15 BF4 7 20 -0.301 4.699 logit 3.1387 3.1109 3.1649 microM 0.02723 #> 7 IM16 BF4 13 30 -4.301 4.699 probit 3.1804 3.1419 3.2158 microM 0.04514 #> 8 IM16 BF4 13 30 -4.301 4.699 logit 3.1814 3.1424 3.2172 microM 0.04553 #> 9 IM17 BF4 10 20 -1.301 4.699 probit 2.4317 2.3632 2.4909 microM 0.04773 #> 10 IM17 BF4 10 20 -1.301 4.699 logit 2.4353 2.3618 2.4981 microM 0.05050 #> 11 IM18 BF4 10 17 -2.301 2.699 probit 1.4015 1.3052 1.4803 microM 0.05611 #> 12 IM18 BF4 10 17 -2.301 2.699 logit 1.4051 1.3023 1.4881 microM 0.05898 #> 13 IM19 BF4 13 22 -5.301 2.699 probit 0.7158 0.6690 0.7580 microM 0.02956 #> 14 IM19 BF4 13 22 -5.301 2.699 logit 0.7172 0.6672 0.7620 microM 0.03210 #> 15 IM1-10 BF4 11 20 -6.301 2.699 probit -0.1790 -0.2628 -0.1088 microM 0.04099 #> 16 IM1-10 BF4 11 20 -6.301 2.699 logit -0.1831 -0.2690 -0.1114 microM 0.04192 #> a b ED50 ED50 2.5% ED50 97.5% EDx10 EDx10 2.5% #> 1 8707.5571 -0.7536 8707.5571 7183.0127 1.023e+04 1.590e+03 968.72501 #> 2 8832.8773 1.2676 8832.8773 7306.8669 1.036e+04 1.561e+03 925.39582 #> 3 3501.1967 -0.6619 3501.1967 3168.9639 3.833e+03 5.051e+02 395.26341 #> 4 3519.5773 1.1105 3519.5773 3179.2923 3.860e+03 4.866e+02 371.84710 #> 5 1379.9019 -0.7858 1379.9019 1296.3162 1.463e+03 2.701e+02 233.25320 #> 6 1376.4086 1.2976 1376.4086 1290.8397 1.462e+03 2.531e+02 215.79719 #> 7 1515.0427 -0.8896 1515.0427 1386.3308 1.644e+03 3.588e+02 283.79434 #> 8 1518.4644 1.4686 1518.4644 1387.9173 1.649e+03 3.401e+02 262.20564 #> 9 270.2279 -0.6800 270.2279 230.7905 3.097e+02 4.105e+01 27.78507 #> 10 272.4526 1.1401 272.4526 230.0588 3.148e+02 3.966e+01 25.34948 #> 11 25.2059 -0.5423 25.2059 20.1927 3.022e+01 2.372e+00 1.29116 #> 12 25.4145 0.9017 25.4145 20.0576 3.077e+01 2.223e+00 1.09707 #> 13 5.1971 -0.6231 5.1971 4.6665 5.728e+00 6.646e-01 0.49235 #> 14 5.2141 1.0511 5.2141 4.6477 5.781e+00 6.446e-01 0.46046 #> 15 0.6622 -0.5416 0.6622 0.5460 7.783e-01 6.213e-02 0.03513 #> 16 0.6560 0.9018 0.6560 0.5383 7.737e-01 5.738e-02 0.03163 #> EDx10 97.5% EDx20 EDx20 2.5% EDx20 97.5% #> 1 2.211e+03 2850.328 2.019e+03 3681.2703 #> 2 2.196e+03 2958.988 2.092e+03 3826.1457 #> 3 6.149e+02 981.743 8.254e+02 1138.0862 #> 4 6.014e+02 1010.061 8.414e+02 1178.7611 #> 5 3.070e+02 472.838 4.257e+02 520.0197 #> 6 2.905e+02 472.906 4.239e+02 521.8955 #> 7 4.337e+02 588.259 4.999e+02 676.6627 #> 8 4.181e+02 590.824 4.972e+02 684.4677 #> 9 5.431e+01 78.383 5.955e+01 97.2142 #> 10 5.396e+01 80.763 5.975e+01 101.7713 #> 11 3.454e+00 5.339 3.544e+00 7.1350 #> 12 3.348e+00 5.463 3.489e+00 7.4370 #> 13 8.369e-01 1.346 1.084e+00 1.6086 #> 14 8.288e-01 1.394 1.106e+00 1.6832 #> 15 8.912e-02 0.140 9.501e-02 0.1850 #> 16 8.314e-02 0.141 9.588e-02 0.1862