R version 3.3.3 (2017-03-06) -- "Another Canoe" Copyright (C) 2017 The R Foundation for Statistical Computing Platform: x86_64-pc-linux-gnu (64-bit) R is free software and comes with ABSOLUTELY NO WARRANTY. You are welcome to redistribute it under certain conditions. Type 'license()' or 'licence()' for distribution details. R is a collaborative project with many contributors. Type 'contributors()' for more information and 'citation()' on how to cite R or R packages in publications. Type 'demo()' for some demos, 'help()' for on-line help, or 'help.start()' for an HTML browser interface to help. Type 'q()' to quit R. > library(drfit) > data(pyrithione) > rpyr <- drfit(pyrithione,linlogit=TRUE,linlogitWrong=c("MSPT","MSPHI","PyS")) Na Pyrithion: Fitting data... Waiting for profiling to be done... Pyridin: Fitting data... PyNO: Fitting data... (PT)2: Fitting data... Waiting for profiling to be done... MSO2P: Fitting data... MSPHI: Fitting data... Waiting for profiling to be done... PyS: Fitting data... Waiting for profiling to be done... Zn Pyrithion: Fitting data... Waiting for profiling to be done... Cu Pyrithion: Fitting data... Waiting for profiling to be done... Fe Pyrithion: Fitting data... Waiting for profiling to be done... MSPT: Fitting data... Waiting for profiling to be done... TBT: Fitting data... Waiting for profiling to be done... NaJ: Fitting data... Warning message: In pnorm(-log10(dose), -logED50, scale) : NaNs produced > print(rpyr,digits=2) Substance ndl n lld lhd mtype logED50 2.5% 97.5% unit sigma 1 Na Pyrithion 20 108 -2.11 2.0 linlogit -0.35 -0.43 -0.26 microM 0.21 2 Pyridin 19 161 0.59 3.7 inactive NA NA NA microM NA 3 PyNO 19 81 0.59 3.7 no fit NA NA NA microM 0.11 4 (PT)2 19 81 -2.41 2.0 linlogit -0.42 -0.53 NA microM 0.21 5 MSO2P 28 108 -1.71 3.7 inactive NA NA NA microM NA 6 MSPHI 19 81 0.59 3.7 probit 3.66 3.55 3.88 microM 0.13 7 PyS 18 80 -0.41 3.0 probit 2.68 NA NA microM 0.13 8 Zn Pyrithion 27 81 -2.11 2.0 linlogit -0.41 -0.53 -0.30 microM 0.23 9 Cu Pyrithion 19 79 -2.41 2.0 linlogit -0.31 -0.48 -0.15 microM 0.24 10 Fe Pyrithion 19 81 -2.41 2.0 linlogit -0.35 -0.50 -0.21 microM 0.23 11 MSPT 18 108 -0.41 3.0 probit 2.14 2.07 2.21 microM 0.23 12 TBT 38 135 -2.71 2.4 linlogit -0.16 -0.26 -0.05 microM 0.19 13 NaJ 10 108 0.59 3.3 inactive NA NA NA microM NA a b c 1 -0.35 2.12 -0.267 2 NA NA NA 3 NA NA NA 4 -0.42 1.85 -0.515 5 NA NA NA 6 3.66 0.44 NA 7 2.68 0.13 NA 8 -0.41 1.74 0.611 9 -0.31 1.02 -0.049 10 -0.35 1.18 0.025 11 2.14 0.21 NA 12 -0.16 1.04 -0.024 13 NA NA NA > > proc.time() user system elapsed 1.884 0.680 1.831