1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
|
\name{mkinmod}
\alias{mkinmod}
\title{
Function to set up a kinetic model with one or more state variables.
}
\description{
The function takes a specification, consisting of a list of the observed variables
in the data. Each observed variable is again represented by a list, specifying the
kinetic model type and reaction or transfer to other observed compartments.
}
\usage{
mkinmod(spec = list(parent = list(type = "SFO", to = NA, sink = TRUE)))
}
\arguments{
\item{spec}{
A list of observed variables to be modelled. Each observed variable has to be
represented by a list with the following entries:
\code{type}{ The type of kinetics to use for the variable. Currently, only
single first order kinetics "SFO" or single first order with reversible binding
"SFORB" are implemented. }
\code{to}{ A vector of names of variables to which a transfer is to be assumed
in the model. }
\code{sink}{ Boolean, specifying if transformation to unspecified compounds (sink)
is to be assumed in the model. }
}
}
\value{
A list of class \code{mkinmod} for use with \code{\link{mkinfit}}, containing
\item{diffs}{ A vector of string representations of differential equations,
one for each modelling variable. }
\item{parms}{ A vector of parameter names occurring in the differential equations. }
\item{map}{ A list containing named character vectors for each observed variable, specifying
the modelling variables by which it is represented. }
}
\author{
Johannes Ranke <jranke@{harlan.com,uni-bremen.de}>
}
\examples{
# One parent compound, one metabolite, both single first order.
SFO_SFO <- mkinmod(spec = list(
parent = list(type = "SFO", to = "m1", sink = TRUE),
m1 = list(type = "SFO", to = NA, sink = TRUE)))
}
\keyword{ models }
|