mkin/man, branch nlmixr Fitting kinetic models to chemical degradation data (also on github) https://cgit.jrwb.de/mkin/atom?h=nlmixr 2021-10-05T15:33:52Z Update docs 2021-10-05T15:33:52Z Johannes Ranke jranke@uni-bremen.de 2021-10-05T15:33:52Z urn:sha1:ff83d8b2ba623513d92ac90fac4a1b0ec98c2cb5 Reduce noise in nlmixr.mmkin output in examples 2021-09-29T12:38:38Z Johannes Ranke jranke@uni-bremen.de 2021-09-29T12:38:38Z urn:sha1:cc50f8cad0f608cd2fb9d385f664fc4f53277b2b intervals() methods, more DFOP/tc variants 2021-09-27T18:10:01Z Johannes Ranke jranke@uni-bremen.de 2021-09-27T18:10:01Z urn:sha1:5c15ef747568b3a9a9c094b6aa546dc80e3aa87a Merge branch 'master' into nlmixr 2021-09-16T06:23:57Z Johannes Ranke jranke@uni-bremen.de 2021-09-16T06:23:57Z urn:sha1:212070667de33e4d4adc7f0ae7baf8e18ad51d3f Fix Open EFSA URL, changelog for 1.0.5 2021-09-15T14:54:49Z Johannes Ranke jranke@uni-bremen.de 2021-09-15T14:54:49Z urn:sha1:2e77bf144a81852302571009b1fcd41f021eca4c The EFSA URL failed on winbuilder because some cookie sets a different domain, so I am now using \href{} with the full link as link text instead of \url{} Update test result to corrected data, version bump 2021-09-15T13:30:02Z Johannes Ranke jranke@uni-bremen.de 2021-09-15T13:30:02Z urn:sha1:fab885edd66b6a1d2e660ee6aa70d14474330697 Merge branch 'master' into nlmixr 2021-07-23T16:13:14Z Johannes Ranke jranke@uni-bremen.de 2021-07-23T16:13:14Z urn:sha1:36b67cc7505a0a7f0960d4cb820c527f27e18f9c After the merge, run make test and accept the new snapshot for the mixed model fit for an nlme object Let backtransform_odeparms handle nlmixr formation fractions 2021-06-17T11:58:34Z Johannes Ranke jranke@uni-bremen.de 2021-06-17T11:58:34Z urn:sha1:05baf3bf92cba127fd2319b779db78be86170e5e Also adapt summary.nlmixr.mmkin to correctly handle the way formation fractions are translated to nlmixr Finished 'summary.nlmixr.mmkin', checks, docs 2021-06-11T09:14:45Z Johannes Ranke jranke@uni-bremen.de 2021-06-11T09:14:45Z urn:sha1:0c9b2f0e3c8ce65cb790c9e048476784cbbea070 Rudimentary support for setting up nlmixr models 2021-06-09T15:00:41Z Johannes Ranke jranke@uni-bremen.de 2021-06-09T14:53:31Z urn:sha1:c6eb6b2bb598002523c3d34d71b0e4a99671ccd6 - All degradation models are specified as ODE models. This appears to be fast enough - Error models are being translated to nlmixr as close to the mkin error model as possible. When using the 'saem' backend, it appears not to be possible to use the same error model for more than one observed variable - No support yet for models with parallel formation of metabolites, where the ilr transformation is used in mkin per default - There is a bug in nlmixr which appears to be triggered if the data are not balanced, see nlmixrdevelopment/nlmixr#530 - There is a print and a plot method, the summary method is not finished