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ℹ Loading mkin
Loading required package: parallel
ℹ Testing mkin
✔ | F W S  OK | Context

⠏ |         0 | AIC                                                             
⠏ |         0 | AIC calculation                                                 
✔ |         5 | AIC calculation

⠏ |         0 | analytical                                                      
⠏ |         0 | Analytical solutions for coupled models                         
⠋ |         1 | Analytical solutions for coupled models                         
⠙ |         2 | Analytical solutions for coupled models                         
⠹ |         3 | Analytical solutions for coupled models                         
⠸ |         4 | Analytical solutions for coupled models                         
⠼ |         5 | Analytical solutions for coupled models                         
✔ |         5 | Analytical solutions for coupled models [3.4s]

⠏ |         0 | aw                                                              
⠏ |         0 | Calculation of Akaike weights                                   
✔ |         5 | Calculation of Akaike weights

⠏ |         0 | CAKE_export                                                     
⠏ |         0 | Export dataset for reading into CAKE                            
✔ |         2 | Export dataset for reading into CAKE

⠏ |         0 | confidence                                                      
⠏ |         0 | Confidence intervals and p-values                               
⠼ |         5 | Confidence intervals and p-values                               
⠋ |        11 | Confidence intervals and p-values                               
⠙ |        12 | Confidence intervals and p-values                               
✔ |        12 | Confidence intervals and p-values [1.0s]

⠏ |         0 | error_models                                                    
⠏ |         0 | Error model fitting                                             
⠹ |         3 | Error model fitting                                             
⠸ |         4 | Error model fitting                                             
⠼ |         5 | Error model fitting                                             
⠴ |         6 | Error model fitting                                             
⠧ |         8 | Error model fitting                                             
⠏ |        10 | Error model fitting                                             
⠙ |        12 | Error model fitting                                             
⠸ |        14 | Error model fitting                                             
✔ |        14 | Error model fitting [4.9s]

⠏ |         0 | f_time_norm                                                     
⠏ |         0 | Time step normalisation                                         
✔ |         5 | Time step normalisation

⠏ |         0 | FOCUS_chi2_error_level                                          
⠏ |         0 | Calculation of FOCUS chi2 error levels                          
⠙ |         2 | Calculation of FOCUS chi2 error levels                          
⠸ |         4 | Calculation of FOCUS chi2 error levels                          
✔ |         4 | Calculation of FOCUS chi2 error levels [0.6s]

⠏ |         0 | FOCUS_D_UBA_expertise                                           
⠏ |         0 | Results for FOCUS D established in expertise for UBA (Ranke 2014)
⠋ |         1 | Results for FOCUS D established in expertise for UBA (Ranke 2014)
⠧ |         8 | Results for FOCUS D established in expertise for UBA (Ranke 2014)
⠏ |        10 | Results for FOCUS D established in expertise for UBA (Ranke 2014)
✔ |        14 | Results for FOCUS D established in expertise for UBA (Ranke 2014) [0.8s]

⠏ |         0 | from_max_mean                                                   
⠏ |         0 | Test fitting the decline of metabolites from their maximum      
⠹ |         3 | Test fitting the decline of metabolites from their maximum      
⠸ |         4 | Test fitting the decline of metabolites from their maximum      
✔ |         4 | Test fitting the decline of metabolites from their maximum [0.3s]

⠏ |         0 | logistic                                                        
⠏ |         0 | Fitting the logistic model                                      
⠋ |         1 | Fitting the logistic model                                      
✔ |         1 | Fitting the logistic model [0.2s]

⠏ |         0 | mixed                                                           
⠏ |         0 | Nonlinear mixed-effects models                                  
⠙ |         2 | Nonlinear mixed-effects models                                  
⠹ |         3 | Nonlinear mixed-effects models                                  
⠸ |         4 | Nonlinear mixed-effects models                                  
⠏ |        10 | Nonlinear mixed-effects models                                  
⠙ |        12 | Nonlinear mixed-effects models                                  
⠧ |        18 | Nonlinear mixed-effects models                                  
⠙ |        22 | Nonlinear mixed-effects models                                  
⠹ |        23 | Nonlinear mixed-effects models                                  
✔ |     1  35 | Nonlinear mixed-effects models [26.6s]
────────────────────────────────────────────────────────────────────────────────
Skip (test_mixed.R:161:3): saem results are reproducible for biphasic fits
Reason: Fitting with saemix takes around 10 minutes when using deSolve
────────────────────────────────────────────────────────────────────────────────

⠏ |         0 | mkinds                                                          
⠏ |         0 | Test dataset classes mkinds and mkindsg                         
✔ |         2 | Test dataset classes mkinds and mkindsg

⠏ |         0 | mkinfit_errors                                                  
⠏ |         0 | Special cases of mkinfit calls                                  
⠇ |         9 | Special cases of mkinfit calls                                  
⠏ |        10 | Special cases of mkinfit calls                                  
✔ |        10 | Special cases of mkinfit calls [0.4s]

⠏ |         0 | mkinfit                                                         
⠏ |         0 | mkinfit features                                                
⠋ |         1 | mkinfit features                                                
✔ |         1 | mkinfit features [0.3s]

⠏ |         0 | mkinmod                                                         
⠏ |         0 | mkinmod model generation and printing                           
⠧ |         8 | mkinmod model generation and printing                           
✔ |         8 | mkinmod model generation and printing [0.2s]

⠏ |         0 | mkinpredict_SFO_SFO                                             
⠏ |         0 | Model predictions with mkinpredict                              
⠋ |         1 | Model predictions with mkinpredict                              
✔ |         3 | Model predictions with mkinpredict [0.3s]

⠏ |         0 | nafta                                                           
⠏ |         0 | Evaluations according to 2015 NAFTA guidance                    
⠙ |         2 | Evaluations according to 2015 NAFTA guidance                    
⠇ |         9 | Evaluations according to 2015 NAFTA guidance                    
⠏ |        10 | Evaluations according to 2015 NAFTA guidance                    
✔ |        16 | Evaluations according to 2015 NAFTA guidance [1.5s]

⠏ |         0 | nlme                                                            
⠏ |         0 | Nonlinear mixed-effects models with nlme                        
⠋ |         1 | Nonlinear mixed-effects models with nlme                        
⠙ |         2 | Nonlinear mixed-effects models with nlme                        
⠼ |         5 | Nonlinear mixed-effects models with nlme                        
⠴ |         6 | Nonlinear mixed-effects models with nlme                        
⠧ |         8 | Nonlinear mixed-effects models with nlme                        
⠇ |         9 | Nonlinear mixed-effects models with nlme                        
✔ |         9 | Nonlinear mixed-effects models with nlme [8.3s]

⠏ |         0 | nlmixr                                                          
⠏ |         0 | plot                                                            
⠏ |         0 | Plotting                                                        
⠋ |         1 | Plotting                                                        
⠇ |         9 | Plotting                                                        
⠹ |        13 | Plotting                                                        
⠼ |        15 | Plotting                                                        
✔ |        16 | Plotting [1.3s]

⠏ |         0 | residuals                                                       
⠏ |         0 | Residuals extracted from mkinfit models                         
✔ |         4 | Residuals extracted from mkinfit models

⠏ |         0 | schaefer07_complex_case                                         
⠏ |         0 | Complex test case from Schaefer et al. (2007) Piacenza paper    
⠋ |         1 | Complex test case from Schaefer et al. (2007) Piacenza paper    
✔ |         2 | Complex test case from Schaefer et al. (2007) Piacenza paper [1.5s]

⠏ |         0 | SFORB                                                           
⠏ |         0 | Fitting the SFORB model                                         
⠋ |         1 | Fitting the SFORB model                                         
⠼ |         5 | Fitting the SFORB model                                         
✔ |         7 | Fitting the SFORB model [3.9s]

⠏ |         0 | summary_old_objects                                             
⠏ |         0 | Summaries of old mkinfit objects                                
✔ |         1 | Summaries of old mkinfit objects

⠏ |         0 | summary                                                         
⠏ |         0 | Summary                                                         
⠸ |         4 | Summary                                                         
✔ |         4 | Summary [0.1s]

⠏ |         0 | synthetic_data_for_UBA_2014                                     
⠏ |         0 | Results for synthetic data established in expertise for UBA (Ranke 2014)
⠋ |         1 | Results for synthetic data established in expertise for UBA (Ranke 2014)
⠹ |         3 | Results for synthetic data established in expertise for UBA (Ranke 2014)
✔ |         4 | Results for synthetic data established in expertise for UBA (Ranke 2014) [2.3s]

⠏ |         0 | tests                                                           
⠏ |         0 | Hypothesis tests                                                
⠼ |         5 | Hypothesis tests                                                
⠴ |         6 | Hypothesis tests                                                
⠧ |         8 | Hypothesis tests                                                
⠇ |         9 | Hypothesis tests                                                
✔ |         9 | Hypothesis tests [8.5s]

⠏ |         0 | twa                                                             
⠏ |         0 | Calculation of maximum time weighted average concentrations (TWAs)
⠋ |         1 | Calculation of maximum time weighted average concentrations (TWAs)
⠙ |         2 | Calculation of maximum time weighted average concentrations (TWAs)
⠹ |         3 | Calculation of maximum time weighted average concentrations (TWAs)
⠸ |         4 | Calculation of maximum time weighted average concentrations (TWAs)
✔ |         4 | Calculation of maximum time weighted average concentrations (TWAs) [2.2s]

══ Results ═════════════════════════════════════════════════════════════════════
Duration: 69.0 s

── Skipped tests  ──────────────────────────────────────────────────────────────
• Fitting with saemix takes around 10 minutes when using deSolve (1)

[ FAIL 0 | WARN 0 | SKIP 1 | PASS 206 ]

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