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nlmixr version used for fitting:    2.0.6 
mkin version used for pre-fitting:  Dummy 0.0 for testing 
R version used for fitting:         Dummy R version for testing 
Date of fit:     Dummy date for testing 
Date of summary: Dummy date for testing 

Equations:
d_parent/dt = - ((k1 * g * exp(-k1 * time) + k2 * (1 - g) * exp(-k2 *
           time)) / (g * exp(-k1 * time) + (1 - g) * exp(-k2 * time)))
           * parent
d_m1/dt = + f_parent_to_m1 * ((k1 * g * exp(-k1 * time) + k2 * (1 - g)
           * exp(-k2 * time)) / (g * exp(-k1 * time) + (1 - g) *
           exp(-k2 * time))) * parent - k_m1 * m1

Data:
507 observations of 2 variable(s) grouped in 15 datasets

Degradation model predictions using RxODE

Fitted in test time 0 s

Variance model: Constant variance 

Mean of starting values for individual parameters:
       parent_0        log_k_m1 f_parent_qlogis          log_k1          log_k2 
         100.67           -5.38           -0.09           -2.74           -4.51 
       g_qlogis 
          -0.18 

Mean of starting values for error model parameters:
sigma_parent     sigma_m1 
           3            3 

Fixed degradation parameter values:
None

Results:

Likelihood calculated by gauss3_1.6  
   AIC  BIC logLik
  2510 2569  -1241

Optimised parameters:
                  est. lower  upper
parent_0        100.49  99.6 101.37
log_k_m1         -5.36  -5.5  -5.20
f_parent_qlogis  -0.09  -0.3   0.08
log_k1           -2.78  -3.0  -2.59
log_k2           -4.51  -4.7  -4.35
g_qlogis         -0.12  -0.5   0.21

Correlation: 
                pr_0 l__1 f_p_ lg_1 lg_2
log_k_m1        -0.3                    
f_parent_qlogis -0.2  0.3               
log_k1           0.1  0.1  0.0          
log_k2           0.0  0.3  0.1  0.4     
g_qlogis         0.0 -0.3 -0.1 -0.5 -0.7

Random effects (omega):
                    eta.parent_0 eta.log_k_m1 eta.f_parent_qlogis eta.log_k1
eta.parent_0                 0.2         0.00                0.00       0.00
eta.log_k_m1                 0.0         0.05                0.00       0.00
eta.f_parent_qlogis          0.0         0.00                0.09       0.00
eta.log_k1                   0.0         0.00                0.00       0.09
eta.log_k2                   0.0         0.00                0.00       0.00
eta.g_qlogis                 0.0         0.00                0.00       0.00
                    eta.log_k2 eta.g_qlogis
eta.parent_0              0.00          0.0
eta.log_k_m1              0.00          0.0
eta.f_parent_qlogis       0.00          0.0
eta.log_k1                0.00          0.0
eta.log_k2                0.03          0.0
eta.g_qlogis              0.00          0.1

Variance model:
sigma_parent     sigma_m1 
           4            1 

Backtransformed parameters:
                est. lower upper
parent_0       1e+02 1e+02 1e+02
k_m1           5e-03 4e-03 6e-03
f_parent_to_m1 5e-01 4e-01 5e-01
k1             6e-02 5e-02 7e-02
k2             1e-02 9e-03 1e-02
g              5e-01 4e-01 6e-01

Resulting formation fractions:
             ff
parent_m1   0.5
parent_sink 0.5

Estimated disappearance times:
       DT50 DT90 DT50back DT50_k1 DT50_k2
parent   25  152       46      11      63
m1      147  488       NA      NA      NA

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