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author | Johannes Ranke <jranke@uni-bremen.de> | 2018-01-30 11:06:33 +0100 |
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committer | Johannes Ranke <jranke@uni-bremen.de> | 2018-01-30 11:20:55 +0100 |
commit | 3147a8c1ec1aa81097bd9897b33b703ae3a5d20f (patch) | |
tree | bd863539e7307ce24360d9c47a65614bc2c07938 /README.html | |
parent | bd234377b7fa2ef056544a9299478b265d18d89f (diff) |
Improve documentation of Rocke and Lorenzato model
Static documentation except articles rebuilt by pkgdown
Diffstat (limited to 'README.html')
-rw-r--r-- | README.html | 1 |
1 files changed, 1 insertions, 0 deletions
diff --git a/README.html b/README.html index f4999a38..b3ba4ce1 100644 --- a/README.html +++ b/README.html @@ -153,6 +153,7 @@ $(document).ready(function () { <li>Summary and plotting functions. The <code>summary</code> of an <code>mkinfit</code> object is in fact a full report that should give enough information to be able to approximately reproduce the fit with other tools.</li> <li>The chi-squared error level as defined in the FOCUS kinetics guidance (see below) is calculated for each observed variable.</li> <li>Iteratively reweighted least squares fitting is implemented in a similar way as in KinGUII and CAKE (see below). Simply add the argument <code>reweight.method = "obs"</code> to your call to <code>mkinfit</code> and a separate variance componenent for each of the observed variables will be optimised in a second stage after the primary optimisation algorithm has converged.</li> +<li>Iterative reweighting is also possible using the two-component error model for analytical data of <a href="http://kinfit.r-forge.r-project.org/mkin_static/reference/sigma_rl.html">Rocke and Lorenzato</a> using the argument <code>reweight.method = "tc"</code>.</li> <li>When a metabolite decline phase is not described well by SFO kinetics, SFORB kinetics can be used for the metabolite.</li> </ul> </div> |