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author | Johannes Ranke <jranke@uni-bremen.de> | 2020-11-07 12:54:58 +0100 |
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committer | Johannes Ranke <jranke@uni-bremen.de> | 2020-11-07 12:54:58 +0100 |
commit | 2e37905a7bf0d72751ee7326ef05a268989e49b2 (patch) | |
tree | cd65d87f8ff258304b26f3aa64e5a8c7216400d6 /docs/articles/FOCUS_L_files/figure-html/unnamed-chunk-12-1.png | |
parent | cda47972e2b6a9610e3118dcd2270d7a1c76de3d (diff) |
Create saem generic for fitting saemix models
The reasons for this decision were
- Creating an saemix generic in the saemix package caused problems with
roxygen, because functions like saemix.plot.xy were documented in
their help files as S3 methods, although explicitly exported with
@export
- Creating an saemix generic in this package is possible, but would
make it necessary to load samix with exclude = "saemix" in order to
avoid overwriting the generic when loading saemix.
- The return object of such an saemix generic in this package cannot
be an S3 class with class attribute c("saemix.mmkin", "SaemixObject")
similar to nlme.mmkin, as saemix returns an S4 class.
- Extending the S4 class SaemixObject using simple inheritance to
a class SaemixMmkinObject with additional slots did not work
as expected. When the initialize method was left untouched, it
prevented creation of an SaemixMmkinObject even if it was based
on an initialised SaemixObject, as the initialize method seems
to always be called by new(). This could potentially be circumvented
by a coerce method. If an alternative initialize method was
used, an SaemixMmkinObject could be created. However, the methods
written for SaemixObjects only worked in some instances, either
because they checked for the class, and not for class inheritance
(like compare.saemix), or because the initialize method was called
for some reason. Therefore, the idea of creating a derived S4 class
was abandoned.
- A side effect of this decision is that the introduction of the saem
generic opens the possibility to use the same generic also for other
backends like nlmixr with the SAEM algorithm.
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