Compiled models article, reduce distractions

- Added a section with platform specific notes on getting compiled
models to work to the compiled models article
- Don't return empty SFORB parameter list from endpoints() if there is no
SFORB model
- Avoid warnings when using standardized = TRUE in plot.mmkin()

1 files changed, 63 insertions, 108 deletions

diff --git a/docs/articles/web_only/compiled_models.html b/docs/articles/web_only/compiled_models.html
index 363f0c38..6daabd5e 100644
--- a/docs/articles/web_only/compiled_models.html
+++ b/docs/articles/web_only/compiled_models.html
@@ -31,7 +31,7 @@
       </button>
       <span class="navbar-brand">
         <a class="navbar-link" href="../../index.html">mkin</a>
-        <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">0.9.49.6</span>
+        <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">0.9.49.9</span>
       </span>
     </div>
 
@@ -90,7 +90,7 @@
       <h1>Performance benefit by using compiled model definitions in mkin</h1>
                         <h4 class="author">Johannes Ranke</h4>
             
-            <h4 class="date">2019-11-01</h4>
+            <h4 class="date">2020-04-02</h4>
       
       
       <div class="hidden name"><code>compiled_models.Rmd</code></div>
@@ -99,75 +99,49 @@
 
     
     
-<div id="model-that-can-also-be-solved-with-eigenvalues" class="section level2">
+<div id="how-to-benefit-from-compiled-models" class="section level2">
 <h2 class="hasAnchor">
-<a href="#model-that-can-also-be-solved-with-eigenvalues" class="anchor"></a>Model that can also be solved with Eigenvalues</h2>
-<p>This evaluation is taken from the example section of mkinfit. When using an mkin version equal to or greater than 0.9-36 and a C compiler (gcc) is available, you will see a message that the model is being compiled from autogenerated C code when defining a model using mkinmod. The <code><a href="../../reference/mkinmod.html">mkinmod()</a></code> function checks for presence of the gcc compiler using</p>
-<div class="sourceCode" id="cb1"><pre class="sourceCode r"><code class="sourceCode r"><a class="sourceLine" id="cb1-1" title="1"><span class="kw"><a href="https://rdrr.io/r/base/Sys.which.html">Sys.which</a></span>(<span class="st">"gcc"</span>)</a></code></pre></div>
-<pre><code>##            gcc 
-## "/usr/bin/gcc"</code></pre>
+<a href="#how-to-benefit-from-compiled-models" class="anchor"></a>How to benefit from compiled models</h2>
+<p>When using an mkin version equal to or greater than 0.9-36 and a C compiler is available, you will see a message that the model is being compiled from autogenerated C code when defining a model using mkinmod. Starting from version 0.9.49.9, the <code><a href="../../reference/mkinmod.html">mkinmod()</a></code> function checks for presence of a compiler using</p>
+<div class="sourceCode" id="cb1"><pre class="sourceCode r"><code class="sourceCode r"><a class="sourceLine" id="cb1-1" title="1">pkgbuild<span class="op">::</span><span class="kw"><a href="https://rdrr.io/pkg/pkgbuild/man/has_compiler.html">has_compiler</a></span>()</a></code></pre></div>
+<p>In previous versions, it used <code><a href="https://rdrr.io/r/base/Sys.which.html">Sys.which("gcc")</a></code> for this check.</p>
+<p>On Linux, you need to have the essential build tools like make and gcc or clang installed. On Debian based linux distributions, these will be pulled in by installing the build-essential package.</p>
+<p>On MacOS, which I do not use personally, I have had reports that a compiler is available by default.</p>
+<p>On Windows, you need to install Rtools and have the path to its bin directory in your PATH variable. You do not need to modify the PATH variable when installing Rtools. Instead, I would recommend to put the line</p>
+<div class="sourceCode" id="cb2"><pre class="sourceCode r"><code class="sourceCode r"><a class="sourceLine" id="cb2-1" title="1"><span class="kw"><a href="https://rdrr.io/r/base/Sys.setenv.html">Sys.setenv</a></span>(<span class="dt">PATH =</span> <span class="kw"><a href="https://rdrr.io/r/base/paste.html">paste</a></span>(<span class="st">"C:/Rtools/bin"</span>, <span class="kw"><a href="https://rdrr.io/r/base/Sys.getenv.html">Sys.getenv</a></span>(<span class="st">"PATH"</span>), <span class="dt">sep=</span><span class="st">";"</span>))</a></code></pre></div>
+<p>into your .Rprofile startup file. This is just a text file with some R code that is executed when your R session starts. It has to be named .Rprofile and has to be located in your home directory, which will generally be your Documents folder. You can check the location of the home directory used by R by issuing</p>
+<div class="sourceCode" id="cb3"><pre class="sourceCode r"><code class="sourceCode r"><a class="sourceLine" id="cb3-1" title="1"><span class="kw"><a href="https://rdrr.io/r/base/Sys.getenv.html">Sys.getenv</a></span>(<span class="st">"HOME"</span>)</a></code></pre></div>
+</div>
+<div id="comparison-with-eigenvalue-based-solutions" class="section level2">
+<h2 class="hasAnchor">
+<a href="#comparison-with-eigenvalue-based-solutions" class="anchor"></a>Comparison with Eigenvalue based solutions</h2>
 <p>First, we build a simple degradation model for a parent compound with one metabolite.</p>
-<div class="sourceCode" id="cb3"><pre class="sourceCode r"><code class="sourceCode r"><a class="sourceLine" id="cb3-1" title="1"><span class="kw"><a href="https://rdrr.io/r/base/library.html">library</a></span>(<span class="st">"mkin"</span>, <span class="dt">quietly =</span> <span class="ot">TRUE</span>)</a>
-<a class="sourceLine" id="cb3-2" title="2">SFO_SFO &lt;-<span class="st"> </span><span class="kw"><a href="../../reference/mkinmod.html">mkinmod</a></span>(</a>
-<a class="sourceLine" id="cb3-3" title="3">  <span class="dt">parent =</span> <span class="kw"><a href="../../reference/mkinsub.html">mkinsub</a></span>(<span class="st">"SFO"</span>, <span class="st">"m1"</span>),</a>
-<a class="sourceLine" id="cb3-4" title="4">  <span class="dt">m1 =</span> <span class="kw"><a href="../../reference/mkinsub.html">mkinsub</a></span>(<span class="st">"SFO"</span>))</a></code></pre></div>
+<div class="sourceCode" id="cb4"><pre class="sourceCode r"><code class="sourceCode r"><a class="sourceLine" id="cb4-1" title="1"><span class="kw"><a href="https://rdrr.io/r/base/library.html">library</a></span>(<span class="st">"mkin"</span>, <span class="dt">quietly =</span> <span class="ot">TRUE</span>)</a>
+<a class="sourceLine" id="cb4-2" title="2">SFO_SFO &lt;-<span class="st"> </span><span class="kw"><a href="../../reference/mkinmod.html">mkinmod</a></span>(</a>
+<a class="sourceLine" id="cb4-3" title="3">  <span class="dt">parent =</span> <span class="kw"><a href="../../reference/mkinsub.html">mkinsub</a></span>(<span class="st">"SFO"</span>, <span class="st">"m1"</span>),</a>
+<a class="sourceLine" id="cb4-4" title="4">  <span class="dt">m1 =</span> <span class="kw"><a href="../../reference/mkinsub.html">mkinsub</a></span>(<span class="st">"SFO"</span>))</a></code></pre></div>
 <pre><code>## Successfully compiled differential equation model from auto-generated C code.</code></pre>
-<p>We can compare the performance of the Eigenvalue based solution against the compiled version and the R implementation of the differential equations using the benchmark package.</p>
-<div class="sourceCode" id="cb5"><pre class="sourceCode r"><code class="sourceCode r"><a class="sourceLine" id="cb5-1" title="1"><span class="cf">if</span> (<span class="kw"><a href="https://rdrr.io/r/base/library.html">require</a></span>(rbenchmark)) {</a>
-<a class="sourceLine" id="cb5-2" title="2">  b<span class="fl">.1</span> &lt;-<span class="st"> </span><span class="kw"><a href="https://rdrr.io/pkg/rbenchmark/man/benchmark.html">benchmark</a></span>(</a>
-<a class="sourceLine" id="cb5-3" title="3">    <span class="st">"deSolve, not compiled"</span> =<span class="st"> </span><span class="kw"><a href="../../reference/mkinfit.html">mkinfit</a></span>(SFO_SFO, FOCUS_<span class="dv">2006</span>_D,</a>
-<a class="sourceLine" id="cb5-4" title="4">                                      <span class="dt">solution_type =</span> <span class="st">"deSolve"</span>,</a>
-<a class="sourceLine" id="cb5-5" title="5">                                      <span class="dt">use_compiled =</span> <span class="ot">FALSE</span>, <span class="dt">quiet =</span> <span class="ot">TRUE</span>),</a>
-<a class="sourceLine" id="cb5-6" title="6">    <span class="st">"Eigenvalue based"</span> =<span class="st"> </span><span class="kw"><a href="../../reference/mkinfit.html">mkinfit</a></span>(SFO_SFO, FOCUS_<span class="dv">2006</span>_D,</a>
-<a class="sourceLine" id="cb5-7" title="7">                                 <span class="dt">solution_type =</span> <span class="st">"eigen"</span>, <span class="dt">quiet =</span> <span class="ot">TRUE</span>),</a>
-<a class="sourceLine" id="cb5-8" title="8">    <span class="st">"deSolve, compiled"</span> =<span class="st"> </span><span class="kw"><a href="../../reference/mkinfit.html">mkinfit</a></span>(SFO_SFO, FOCUS_<span class="dv">2006</span>_D,</a>
-<a class="sourceLine" id="cb5-9" title="9">                                  <span class="dt">solution_type =</span> <span class="st">"deSolve"</span>, <span class="dt">quiet =</span> <span class="ot">TRUE</span>),</a>
-<a class="sourceLine" id="cb5-10" title="10">    <span class="dt">replications =</span> <span class="dv">3</span>)</a>
-<a class="sourceLine" id="cb5-11" title="11">  <span class="kw"><a href="https://rdrr.io/r/base/print.html">print</a></span>(b<span class="fl">.1</span>)</a>
-<a class="sourceLine" id="cb5-12" title="12">  factor_SFO_SFO &lt;-<span class="st"> </span><span class="kw"><a href="https://rdrr.io/r/base/Round.html">round</a></span>(b<span class="fl">.1</span>[<span class="st">"1"</span>, <span class="st">"relative"</span>])</a>
-<a class="sourceLine" id="cb5-13" title="13">} <span class="cf">else</span> {</a>
-<a class="sourceLine" id="cb5-14" title="14">  factor_SFO_SFO &lt;-<span class="st"> </span><span class="ot">NA</span></a>
-<a class="sourceLine" id="cb5-15" title="15">  <span class="kw"><a href="https://rdrr.io/r/base/print.html">print</a></span>(<span class="st">"R package rbenchmark is not available"</span>)</a>
-<a class="sourceLine" id="cb5-16" title="16">}</a></code></pre></div>
-<pre><code>## Lade nötiges Paket: rbenchmark</code></pre>
-<pre><code>## Warning in mkinfit(SFO_SFO, FOCUS_2006_D, solution_type = "deSolve",
-## use_compiled = FALSE, : Observations with value of zero were removed from
-## the data</code></pre>
-<pre><code>## Warning in mkinfit(SFO_SFO, FOCUS_2006_D, solution_type = "eigen", quiet =
-## TRUE): Observations with value of zero were removed from the data</code></pre>
-<pre><code>## Warning in mkinfit(SFO_SFO, FOCUS_2006_D, solution_type = "deSolve", quiet
-## = TRUE): Observations with value of zero were removed from the data</code></pre>
-<pre><code>## Warning in mkinfit(SFO_SFO, FOCUS_2006_D, solution_type = "deSolve",
-## use_compiled = FALSE, : Observations with value of zero were removed from
-## the data
-
-## Warning in mkinfit(SFO_SFO, FOCUS_2006_D, solution_type = "deSolve",
-## use_compiled = FALSE, : Observations with value of zero were removed from
-## the data
-
-## Warning in mkinfit(SFO_SFO, FOCUS_2006_D, solution_type = "deSolve",
-## use_compiled = FALSE, : Observations with value of zero were removed from
-## the data</code></pre>
-<pre><code>## Warning in mkinfit(SFO_SFO, FOCUS_2006_D, solution_type = "eigen", quiet =
-## TRUE): Observations with value of zero were removed from the data
-
-## Warning in mkinfit(SFO_SFO, FOCUS_2006_D, solution_type = "eigen", quiet =
-## TRUE): Observations with value of zero were removed from the data
-
-## Warning in mkinfit(SFO_SFO, FOCUS_2006_D, solution_type = "eigen", quiet =
-## TRUE): Observations with value of zero were removed from the data</code></pre>
-<pre><code>## Warning in mkinfit(SFO_SFO, FOCUS_2006_D, solution_type = "deSolve", quiet
-## = TRUE): Observations with value of zero were removed from the data
-
-## Warning in mkinfit(SFO_SFO, FOCUS_2006_D, solution_type = "deSolve", quiet
-## = TRUE): Observations with value of zero were removed from the data
-
-## Warning in mkinfit(SFO_SFO, FOCUS_2006_D, solution_type = "deSolve", quiet
-## = TRUE): Observations with value of zero were removed from the data</code></pre>
+<p>We can compare the performance of the Eigenvalue based solution against the compiled version and the R implementation of the differential equations using the benchmark package. In the output of below code, the warnings about zero being removed from the FOCUS D dataset are suppressed.</p>
+<div class="sourceCode" id="cb6"><pre class="sourceCode r"><code class="sourceCode r"><a class="sourceLine" id="cb6-1" title="1"><span class="cf">if</span> (<span class="kw"><a href="https://rdrr.io/r/base/library.html">require</a></span>(rbenchmark)) {</a>
+<a class="sourceLine" id="cb6-2" title="2">  b<span class="fl">.1</span> &lt;-<span class="st"> </span><span class="kw"><a href="https://rdrr.io/pkg/rbenchmark/man/benchmark.html">benchmark</a></span>(</a>
+<a class="sourceLine" id="cb6-3" title="3">    <span class="st">"deSolve, not compiled"</span> =<span class="st"> </span><span class="kw"><a href="../../reference/mkinfit.html">mkinfit</a></span>(SFO_SFO, FOCUS_<span class="dv">2006</span>_D,</a>
+<a class="sourceLine" id="cb6-4" title="4">                                      <span class="dt">solution_type =</span> <span class="st">"deSolve"</span>,</a>
+<a class="sourceLine" id="cb6-5" title="5">                                      <span class="dt">use_compiled =</span> <span class="ot">FALSE</span>, <span class="dt">quiet =</span> <span class="ot">TRUE</span>),</a>
+<a class="sourceLine" id="cb6-6" title="6">    <span class="st">"Eigenvalue based"</span> =<span class="st"> </span><span class="kw"><a href="../../reference/mkinfit.html">mkinfit</a></span>(SFO_SFO, FOCUS_<span class="dv">2006</span>_D,</a>
+<a class="sourceLine" id="cb6-7" title="7">                                 <span class="dt">solution_type =</span> <span class="st">"eigen"</span>, <span class="dt">quiet =</span> <span class="ot">TRUE</span>),</a>
+<a class="sourceLine" id="cb6-8" title="8">    <span class="st">"deSolve, compiled"</span> =<span class="st"> </span><span class="kw"><a href="../../reference/mkinfit.html">mkinfit</a></span>(SFO_SFO, FOCUS_<span class="dv">2006</span>_D,</a>
+<a class="sourceLine" id="cb6-9" title="9">                                  <span class="dt">solution_type =</span> <span class="st">"deSolve"</span>, <span class="dt">quiet =</span> <span class="ot">TRUE</span>),</a>
+<a class="sourceLine" id="cb6-10" title="10">    <span class="dt">replications =</span> <span class="dv">3</span>)</a>
+<a class="sourceLine" id="cb6-11" title="11">  <span class="kw"><a href="https://rdrr.io/r/base/print.html">print</a></span>(b<span class="fl">.1</span>)</a>
+<a class="sourceLine" id="cb6-12" title="12">  factor_SFO_SFO &lt;-<span class="st"> </span><span class="kw"><a href="https://rdrr.io/r/base/Round.html">round</a></span>(b<span class="fl">.1</span>[<span class="st">"1"</span>, <span class="st">"relative"</span>])</a>
+<a class="sourceLine" id="cb6-13" title="13">} <span class="cf">else</span> {</a>
+<a class="sourceLine" id="cb6-14" title="14">  factor_SFO_SFO &lt;-<span class="st"> </span><span class="ot">NA</span></a>
+<a class="sourceLine" id="cb6-15" title="15">  <span class="kw"><a href="https://rdrr.io/r/base/print.html">print</a></span>(<span class="st">"R package rbenchmark is not available"</span>)</a>
+<a class="sourceLine" id="cb6-16" title="16">}</a></code></pre></div>
 <pre><code>##                    test replications elapsed relative user.self sys.self
-## 3     deSolve, compiled            3   3.143    1.000     3.142        0
-## 1 deSolve, not compiled            3  29.169    9.281    29.154        0
-## 2      Eigenvalue based            3   4.358    1.387     4.356        0
+## 3     deSolve, compiled            3   3.239    1.000     3.237        0
+## 1 deSolve, not compiled            3  29.758    9.187    29.739        0
+## 2      Eigenvalue based            3   4.558    1.407     4.554        0
 ##   user.child sys.child
 ## 3          0         0
 ## 1          0         0
@@ -178,52 +152,32 @@
 <h2 class="hasAnchor">
 <a href="#model-that-can-not-be-solved-with-eigenvalues" class="anchor"></a>Model that can not be solved with Eigenvalues</h2>
 <p>This evaluation is also taken from the example section of mkinfit.</p>
-<div class="sourceCode" id="cb14"><pre class="sourceCode r"><code class="sourceCode r"><a class="sourceLine" id="cb14-1" title="1"><span class="cf">if</span> (<span class="kw"><a href="https://rdrr.io/r/base/library.html">require</a></span>(rbenchmark)) {</a>
-<a class="sourceLine" id="cb14-2" title="2">  FOMC_SFO &lt;-<span class="st"> </span><span class="kw"><a href="../../reference/mkinmod.html">mkinmod</a></span>(</a>
-<a class="sourceLine" id="cb14-3" title="3">    <span class="dt">parent =</span> <span class="kw"><a href="../../reference/mkinsub.html">mkinsub</a></span>(<span class="st">"FOMC"</span>, <span class="st">"m1"</span>),</a>
-<a class="sourceLine" id="cb14-4" title="4">    <span class="dt">m1 =</span> <span class="kw"><a href="../../reference/mkinsub.html">mkinsub</a></span>( <span class="st">"SFO"</span>))</a>
-<a class="sourceLine" id="cb14-5" title="5"></a>
-<a class="sourceLine" id="cb14-6" title="6">  b<span class="fl">.2</span> &lt;-<span class="st"> </span><span class="kw"><a href="https://rdrr.io/pkg/rbenchmark/man/benchmark.html">benchmark</a></span>(</a>
-<a class="sourceLine" id="cb14-7" title="7">    <span class="st">"deSolve, not compiled"</span> =<span class="st"> </span><span class="kw"><a href="../../reference/mkinfit.html">mkinfit</a></span>(FOMC_SFO, FOCUS_<span class="dv">2006</span>_D,</a>
-<a class="sourceLine" id="cb14-8" title="8">                                      <span class="dt">use_compiled =</span> <span class="ot">FALSE</span>, <span class="dt">quiet =</span> <span class="ot">TRUE</span>),</a>
-<a class="sourceLine" id="cb14-9" title="9">    <span class="st">"deSolve, compiled"</span> =<span class="st"> </span><span class="kw"><a href="../../reference/mkinfit.html">mkinfit</a></span>(FOMC_SFO, FOCUS_<span class="dv">2006</span>_D, <span class="dt">quiet =</span> <span class="ot">TRUE</span>),</a>
-<a class="sourceLine" id="cb14-10" title="10">    <span class="dt">replications =</span> <span class="dv">3</span>)</a>
-<a class="sourceLine" id="cb14-11" title="11">  <span class="kw"><a href="https://rdrr.io/r/base/print.html">print</a></span>(b<span class="fl">.2</span>)</a>
-<a class="sourceLine" id="cb14-12" title="12">  factor_FOMC_SFO &lt;-<span class="st"> </span><span class="kw"><a href="https://rdrr.io/r/base/Round.html">round</a></span>(b<span class="fl">.2</span>[<span class="st">"1"</span>, <span class="st">"relative"</span>])</a>
-<a class="sourceLine" id="cb14-13" title="13">} <span class="cf">else</span> {</a>
-<a class="sourceLine" id="cb14-14" title="14">  factor_FOMC_SFO &lt;-<span class="st"> </span><span class="ot">NA</span></a>
-<a class="sourceLine" id="cb14-15" title="15">  <span class="kw"><a href="https://rdrr.io/r/base/print.html">print</a></span>(<span class="st">"R package benchmark is not available"</span>)</a>
-<a class="sourceLine" id="cb14-16" title="16">}</a></code></pre></div>
+<div class="sourceCode" id="cb8"><pre class="sourceCode r"><code class="sourceCode r"><a class="sourceLine" id="cb8-1" title="1"><span class="cf">if</span> (<span class="kw"><a href="https://rdrr.io/r/base/library.html">require</a></span>(rbenchmark)) {</a>
+<a class="sourceLine" id="cb8-2" title="2">  FOMC_SFO &lt;-<span class="st"> </span><span class="kw"><a href="../../reference/mkinmod.html">mkinmod</a></span>(</a>
+<a class="sourceLine" id="cb8-3" title="3">    <span class="dt">parent =</span> <span class="kw"><a href="../../reference/mkinsub.html">mkinsub</a></span>(<span class="st">"FOMC"</span>, <span class="st">"m1"</span>),</a>
+<a class="sourceLine" id="cb8-4" title="4">    <span class="dt">m1 =</span> <span class="kw"><a href="../../reference/mkinsub.html">mkinsub</a></span>( <span class="st">"SFO"</span>))</a>
+<a class="sourceLine" id="cb8-5" title="5"></a>
+<a class="sourceLine" id="cb8-6" title="6">  b<span class="fl">.2</span> &lt;-<span class="st"> </span><span class="kw"><a href="https://rdrr.io/pkg/rbenchmark/man/benchmark.html">benchmark</a></span>(</a>
+<a class="sourceLine" id="cb8-7" title="7">    <span class="st">"deSolve, not compiled"</span> =<span class="st"> </span><span class="kw"><a href="../../reference/mkinfit.html">mkinfit</a></span>(FOMC_SFO, FOCUS_<span class="dv">2006</span>_D,</a>
+<a class="sourceLine" id="cb8-8" title="8">                                      <span class="dt">use_compiled =</span> <span class="ot">FALSE</span>, <span class="dt">quiet =</span> <span class="ot">TRUE</span>),</a>
+<a class="sourceLine" id="cb8-9" title="9">    <span class="st">"deSolve, compiled"</span> =<span class="st"> </span><span class="kw"><a href="../../reference/mkinfit.html">mkinfit</a></span>(FOMC_SFO, FOCUS_<span class="dv">2006</span>_D, <span class="dt">quiet =</span> <span class="ot">TRUE</span>),</a>
+<a class="sourceLine" id="cb8-10" title="10">    <span class="dt">replications =</span> <span class="dv">3</span>)</a>
+<a class="sourceLine" id="cb8-11" title="11">  <span class="kw"><a href="https://rdrr.io/r/base/print.html">print</a></span>(b<span class="fl">.2</span>)</a>
+<a class="sourceLine" id="cb8-12" title="12">  factor_FOMC_SFO &lt;-<span class="st"> </span><span class="kw"><a href="https://rdrr.io/r/base/Round.html">round</a></span>(b<span class="fl">.2</span>[<span class="st">"1"</span>, <span class="st">"relative"</span>])</a>
+<a class="sourceLine" id="cb8-13" title="13">} <span class="cf">else</span> {</a>
+<a class="sourceLine" id="cb8-14" title="14">  factor_FOMC_SFO &lt;-<span class="st"> </span><span class="ot">NA</span></a>
+<a class="sourceLine" id="cb8-15" title="15">  <span class="kw"><a href="https://rdrr.io/r/base/print.html">print</a></span>(<span class="st">"R package benchmark is not available"</span>)</a>
+<a class="sourceLine" id="cb8-16" title="16">}</a></code></pre></div>
 <pre><code>## Successfully compiled differential equation model from auto-generated C code.</code></pre>
-<pre><code>## Warning in mkinfit(FOMC_SFO, FOCUS_2006_D, use_compiled = FALSE, quiet =
-## TRUE): Observations with value of zero were removed from the data</code></pre>
-<pre><code>## Warning in mkinfit(FOMC_SFO, FOCUS_2006_D, quiet = TRUE): Observations with
-## value of zero were removed from the data</code></pre>
-<pre><code>## Warning in mkinfit(FOMC_SFO, FOCUS_2006_D, use_compiled = FALSE, quiet =
-## TRUE): Observations with value of zero were removed from the data
-
-## Warning in mkinfit(FOMC_SFO, FOCUS_2006_D, use_compiled = FALSE, quiet =
-## TRUE): Observations with value of zero were removed from the data
-
-## Warning in mkinfit(FOMC_SFO, FOCUS_2006_D, use_compiled = FALSE, quiet =
-## TRUE): Observations with value of zero were removed from the data</code></pre>
-<pre><code>## Warning in mkinfit(FOMC_SFO, FOCUS_2006_D, quiet = TRUE): Observations with
-## value of zero were removed from the data
-
-## Warning in mkinfit(FOMC_SFO, FOCUS_2006_D, quiet = TRUE): Observations with
-## value of zero were removed from the data
-
-## Warning in mkinfit(FOMC_SFO, FOCUS_2006_D, quiet = TRUE): Observations with
-## value of zero were removed from the data</code></pre>
 <pre><code>##                    test replications elapsed relative user.self sys.self
-## 2     deSolve, compiled            3   4.840    1.000     4.837        0
-## 1 deSolve, not compiled            3  54.338   11.227    54.309        0
+## 2     deSolve, compiled            3   4.984    1.000     4.981    0.000
+## 1 deSolve, not compiled            3  55.358   11.107    55.326    0.003
 ##   user.child sys.child
 ## 2          0         0
 ## 1          0         0</code></pre>
 <p>Here we get a performance benefit of a factor of 11 using the version of the differential equation model compiled from C code!</p>
-<p>This vignette was built with mkin 0.9.49.6 on</p>
-<pre><code>## R version 3.6.1 (2019-07-05)
+<p>This vignette was built with mkin 0.9.49.9 on</p>
+<pre><code>## R version 3.6.3 (2020-02-29)
 ## Platform: x86_64-pc-linux-gnu (64-bit)
 ## Running under: Debian GNU/Linux 10 (buster)</code></pre>
 <pre><code>## CPU model: AMD Ryzen 7 1700 Eight-Core Processor</code></pre>
@@ -236,7 +190,8 @@
       <h2 class="hasAnchor">
 <a href="#tocnav" class="anchor"></a>Contents</h2>
       <ul class="nav nav-pills nav-stacked">
-<li><a href="#model-that-can-also-be-solved-with-eigenvalues">Model that can also be solved with Eigenvalues</a></li>
+<li><a href="#how-to-benefit-from-compiled-models">How to benefit from compiled models</a></li>
+      <li><a href="#comparison-with-eigenvalue-based-solutions">Comparison with Eigenvalue based solutions</a></li>
       <li><a href="#model-that-can-not-be-solved-with-eigenvalues">Model that can not be solved with Eigenvalues</a></li>
       </ul>
 </div>