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authorJohannes Ranke <jranke@uni-bremen.de>2022-08-10 13:21:34 +0200
committerJohannes Ranke <jranke@uni-bremen.de>2022-08-10 13:21:34 +0200
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+degradation models and one or more error models — mhmkin"><meta property="og:description" content="The name of the methods expresses that (multiple) hierarchichal
+(also known as multilevel) multicompartment kinetic models are
+fitted. Our kinetic models are nonlinear, so we can use various nonlinear
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+ <div class="col-md-9 contents">
+ <div class="page-header">
+ <h1>Fit nonlinear mixed-effects models built from one or more kinetic
+degradation models and one or more error models</h1>
+ <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/mhmkin.R" class="external-link"><code>R/mhmkin.R</code></a></small>
+ <div class="hidden name"><code>mhmkin.Rd</code></div>
+ </div>
+
+ <div class="ref-description">
+ <p>The name of the methods expresses that (<strong>m</strong>ultiple) <strong>h</strong>ierarchichal
+(also known as multilevel) <strong>m</strong>ulticompartment <strong>kin</strong>etic models are
+fitted. Our kinetic models are nonlinear, so we can use various nonlinear
+mixed-effects model fitting functions.</p>
+ </div>
+
+ <div id="ref-usage">
+ <div class="sourceCode"><pre><code>mhmkin(objects, backend = "saemix", algorithm = "saem", ...)
+
+# S3 method for list
+mhmkin(
+ objects,
+ backend = "saemix",
+ ...,
+ cores = if (Sys.info()["sysname"] == "Windows") 1 else parallel::detectCores(),
+ cluster = NULL
+)
+
+# S3 method for mhmkin
+[(x, i, j, ..., drop = FALSE)
+
+# S3 method for mhmkin
+print(x, ...)</code></pre></div>
+ </div>
+
+ <div id="arguments">
+ <h2>Arguments</h2>
+ <dl><dt>objects</dt>
+<dd><p>A list of <a href="mmkin.html">mmkin</a> objects containing fits of the same
+degradation models to the same data, but using different error models.</p></dd>
+
+
+<dt>backend</dt>
+<dd><p>The backend to be used for fitting. Currently, only saemix is
+supported</p></dd>
+
+
+<dt>algorithm</dt>
+<dd><p>The algorithm to be used for fitting (currently not used)</p></dd>
+
+
+<dt>...</dt>
+<dd><p>Further arguments that will be passed to the nonlinear mixed-effects
+model fitting function.</p></dd>
+
+
+<dt>cores</dt>
+<dd><p>The number of cores to be used for multicore processing. This
+is only used when the <code>cluster</code> argument is <code>NULL</code>. On Windows
+machines, cores &gt; 1 is not supported, you need to use the <code>cluster</code>
+argument to use multiple logical processors. Per default, all cores detected
+by <code><a href="https://rdrr.io/r/parallel/detectCores.html" class="external-link">parallel::detectCores()</a></code> are used, except on Windows where the default
+is 1.</p></dd>
+
+
+<dt>cluster</dt>
+<dd><p>A cluster as returned by makeCluster to be used for
+parallel execution.</p></dd>
+
+
+<dt>x</dt>
+<dd><p>An mhmkin object.</p></dd>
+
+
+<dt>i</dt>
+<dd><p>Row index selecting the fits for specific models</p></dd>
+
+
+<dt>j</dt>
+<dd><p>Column index selecting the fits to specific datasets</p></dd>
+
+
+<dt>drop</dt>
+<dd><p>If FALSE, the method always returns an mhmkin object, otherwise
+either a list of fit objects or a single fit object.</p></dd>
+
+</dl></div>
+ <div id="value">
+ <h2>Value</h2>
+
+
+<p>A two-dimensional <a href="https://rdrr.io/r/base/array.html" class="external-link">array</a> of fit objects and/or try-errors that can
+be indexed using the degradation model names for the first index (row index)
+and the error model names for the second index (column index), with class
+attribute 'mhmkin'.</p>
+
+
+<p>An object of class <code>mhmkin</code>.</p>
+ </div>
+ <div id="see-also">
+ <h2>See also</h2>
+ <div class="dont-index"><p><code>[.mhmkin</code> for subsetting mhmkin objects</p></div>
+ </div>
+ <div id="author">
+ <h2>Author</h2>
+ <p>Johannes Ranke</p>
+ </div>
+
+ </div>
+ <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar">
+ <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2>
+ </nav></div>
+</div>
+
+
+ <footer><div class="copyright">
+ <p></p><p>Developed by Johannes Ranke.</p>
+</div>
+
+<div class="pkgdown">
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