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authorJohannes Ranke <jranke@uni-bremen.de>2018-07-18 15:18:30 +0200
committerJohannes Ranke <jranke@uni-bremen.de>2018-07-18 15:58:46 +0200
commit0b98c459c30a0629a728acf6b311de035c55fb64 (patch)
treef146faf4802da38862aa14b0268265f3fad9ba34 /man/synthetic_data_for_UBA.Rd
parentd3ed95f2a0a43ed74b02ea90e35d043ed4e1e72f (diff)
Correct references to the Rocke and Lorenzato model
Rename 'sigma_rl' to 'sigma_twocomp' as the Rocke and Lorenzato model assumes lognormal distribution for large y. Rebuild static documentation.
Diffstat (limited to 'man/synthetic_data_for_UBA.Rd')
-rw-r--r--man/synthetic_data_for_UBA.Rd5
1 files changed, 4 insertions, 1 deletions
diff --git a/man/synthetic_data_for_UBA.Rd b/man/synthetic_data_for_UBA.Rd
index a9df9767..f9d3c77b 100644
--- a/man/synthetic_data_for_UBA.Rd
+++ b/man/synthetic_data_for_UBA.Rd
@@ -13,7 +13,10 @@
Variance component 'b' is also based on a normal distribution, but with a standard deviation of 7.
Variance component 'c' is based on the error model from Rocke and Lorenzato (1995), with the
minimum standard deviation (for small y values) of 0.5, and a proportionality constant of 0.07
- for the increase of the standard deviation with y.
+ for the increase of the standard deviation with y. Note that this is a simplified version
+ of the error model proposed by Rocke and Lorenzato (1995), as in their model the error of the
+ measured values approximates lognormal distribution for high values, whereas we are using
+ normally distributed error components all along.
Initial concentrations for metabolites and all values where adding the variance component resulted
in a value below the assumed limit of detection of 0.1 were set to \code{NA}.

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