Remove nlmixr interface for release of mkin 1.1.0

I am postponing my attempts to get the nlmixr interface to CRAN, given
some problems with nlmixr using R-devel under Windows, see
https://github.com/nlmixrdevelopment/nlmixr/issues/596
and
https://github.com/r-hub/rhub/issues/512,
which is fixed by the removal of nlmixr from the testsuite.

For the tests to be more platform independent, the biphasic mixed
effects models test dataset was defined in a way that fitting
should be more robust (less ill-defined).

1 files changed, 21 insertions, 24 deletions

diff --git a/test.log b/test.log
index aa74c329..890d921c 100644
--- a/test.log
+++ b/test.log
@@ -3,52 +3,49 @@ Loading required package: parallel
 ℹ Testing mkin
 ✔ | F W S  OK | Context
 ✔ |         5 | AIC calculation
-✔ |         5 | Analytical solutions for coupled models [4.2s]
+✔ |         5 | Analytical solutions for coupled models [3.3s]
 ✔ |         5 | Calculation of Akaike weights
 ✔ |         2 | Export dataset for reading into CAKE
 ✔ |        12 | Confidence intervals and p-values [1.0s]
-⠋ |         1 | Dimethenamid data from 2018                                     
-✔ |     1  27 | Dimethenamid data from 2018 [63.8s]
+✔ |     1  12 | Dimethenamid data from 2018 [31.2s]
 ────────────────────────────────────────────────────────────────────────────────
-Skip (test_dmta.R:164:3): Different backends get consistent results for SFO-SFO3+, dimethenamid data
+Skip (test_dmta.R:98:3): Different backends get consistent results for SFO-SFO3+, dimethenamid data
 Reason: Fitting this ODE model with saemix takes about 15 minutes on my system
 ────────────────────────────────────────────────────────────────────────────────
-✔ |        14 | Error model fitting [7.0s]
+✔ |        14 | Error model fitting [4.7s]
 ✔ |         5 | Time step normalisation
-✔ |         4 | Calculation of FOCUS chi2 error levels [0.8s]
-✔ |        14 | Results for FOCUS D established in expertise for UBA (Ranke 2014) [1.1s]
-✔ |         4 | Test fitting the decline of metabolites from their maximum [0.5s]
-✔ |         1 | Fitting the logistic model [0.3s]
-⠇ |         9 | Nonlinear mixed-effects models                                  
-✔ |     1  14 | Nonlinear mixed-effects models [1.6s]
+✔ |         4 | Calculation of FOCUS chi2 error levels [0.5s]
+✔ |        14 | Results for FOCUS D established in expertise for UBA (Ranke 2014) [0.8s]
+✔ |         4 | Test fitting the decline of metabolites from their maximum [0.3s]
+✔ |         1 | Fitting the logistic model [0.2s]
+✔ |     1  12 | Nonlinear mixed-effects models [0.2s]
 ────────────────────────────────────────────────────────────────────────────────
 Skip (test_mixed.R:68:3): saemix results are reproducible for biphasic fits
 Reason: Fitting with saemix takes around 10 minutes when using deSolve
 ────────────────────────────────────────────────────────────────────────────────
 ✔ |         3 | Test dataset classes mkinds and mkindsg
-✔ |        10 | Special cases of mkinfit calls [0.6s]
-✔ |         3 | mkinfit features [1.1s]
+✔ |        10 | Special cases of mkinfit calls [0.4s]
+✔ |         3 | mkinfit features [0.6s]
 ✔ |         8 | mkinmod model generation and printing [0.2s]
 ✔ |         3 | Model predictions with mkinpredict [0.3s]
-✔ |        16 | Evaluations according to 2015 NAFTA guidance [2.0s]
-✔ |         9 | Nonlinear mixed-effects models with nlme [9.1s]
-✔ |        16 | Plotting [1.5s]
+✔ |        16 | Evaluations according to 2015 NAFTA guidance [1.4s]
+✔ |         9 | Nonlinear mixed-effects models with nlme [8.0s]
+✔ |        16 | Plotting [1.3s]
 ✔ |         4 | Residuals extracted from mkinfit models
-✔ |        23 | saemix parent models [29.3s]
-✔ |         2 | Complex test case from Schaefer et al. (2007) Piacenza paper [1.6s]
-✔ |         7 | Fitting the SFORB model [4.6s]
+✔ |        23 | saemix parent models [26.7s]
+✔ |         2 | Complex test case from Schaefer et al. (2007) Piacenza paper [1.4s]
+✔ |         7 | Fitting the SFORB model [3.6s]
 ✔ |         1 | Summaries of old mkinfit objects
 ✔ |         4 | Summary [0.1s]
-✔ |         4 | Results for synthetic data established in expertise for UBA (Ranke 2014) [2.5s]
-✔ |         9 | Hypothesis tests [9.3s]
-✔ |         2 | tffm0
+✔ |         4 | Results for synthetic data established in expertise for UBA (Ranke 2014) [2.2s]
+✔ |         9 | Hypothesis tests [8.1s]
 ✔ |         4 | Calculation of maximum time weighted average concentrations (TWAs) [2.2s]
 
 ══ Results ═════════════════════════════════════════════════════════════════════
-Duration: 145.2 s
+Duration: 99.2 s
 
 ── Skipped tests  ──────────────────────────────────────────────────────────────
 • Fitting this ODE model with saemix takes about 15 minutes on my system (1)
 • Fitting with saemix takes around 10 minutes when using deSolve (1)
 
-[ FAIL 0 | WARN 0 | SKIP 2 | PASS 240 ]
+[ FAIL 0 | WARN 0 | SKIP 2 | PASS 221 ]