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author | Johannes Ranke <jranke@uni-bremen.de> | 2022-02-28 11:17:56 +0100 |
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committer | Johannes Ranke <jranke@uni-bremen.de> | 2022-02-28 11:17:56 +0100 |
commit | d68f7cc800fe2342642056780b915821dbe113e0 (patch) | |
tree | 969298f89c8c76bcb03d6d84186ab302c0fd26d7 /tests/testthat/test-dmta.R | |
parent | 6b7b93c29115d75bf10c63b61f565a61a2d74498 (diff) |
With saemix 3.0 on CRAN there's no need to check for it in tests
Diffstat (limited to 'tests/testthat/test-dmta.R')
-rw-r--r-- | tests/testthat/test-dmta.R | 64 |
1 files changed, 64 insertions, 0 deletions
diff --git a/tests/testthat/test-dmta.R b/tests/testthat/test-dmta.R new file mode 100644 index 00000000..12bbcb8e --- /dev/null +++ b/tests/testthat/test-dmta.R @@ -0,0 +1,64 @@ +local_edition(3) + +# Data +dmta_ds <- lapply(1:7, function(i) { + ds_i <- dimethenamid_2018$ds[[i]]$data + ds_i[ds_i$name == "DMTAP", "name"] <- "DMTA" + ds_i$time <- ds_i$time * dimethenamid_2018$f_time_norm[i] + ds_i +}) +names(dmta_ds) <- sapply(dimethenamid_2018$ds, function(ds) ds$title) +dmta_ds[["Elliot"]] <- rbind(dmta_ds[["Elliot 1"]], dmta_ds[["Elliot 2"]]) +dmta_ds[["Elliot 1"]] <- dmta_ds[["Elliot 2"]] <- NULL + +# mkin +nlm_dfop <- mmkin("DFOP", dmta_ds) +nlm_dfop_tc <- mmkin("DFOP", dmta_ds, error_model = "tc") +parms(nlm_dfop_tc) + +# nlme +nlme_dfop_tc <- nlme(nlm_dfop_tc) +summary(nlme_dfop_tc) +intervals(nlme_dfop_tc) + +# saemix +saem_saemix_dfop_tc <- saem(nlm_dfop_tc) +saem_saemix_dfop_tc$so <- saemix::llgq.saemix(saem_saemix_dfop_tc$so) +summary(saem_saemix_dfop_tc) +intervals(saem_saemix_dfop_tc) +AIC(saem_saemix_dfop_tc$so) +AIC(saem_saemix_dfop_tc$so, "gq") +AIC(saem_saemix_dfop_tc$so, "lin") +saemix::plot(saem_saemix_dfop_tc$so, plot.type = "likelihood") +saemix::plot(saem_saemix_dfop_tc$so, plot.type = "convergence") + +saem_saemix_dfop_tc_1k <- saem(nlm_dfop_tc, nbiter.saemix = c(1000, 100)) +AIC(saem_saemix_dfop_tc_1k$so) +saemix::plot(saem_saemix_dfop_tc_1k$so, plot.type = "convergence") +saemix::plot(saem_saemix_dfop_tc_1k$so, plot.type = "likelihood") +intervals(saem_saemix_dfop_tc_1k) + +saem_saemix_dfop_tc_1.5k <- saem(nlm_dfop_tc, nbiter.saemix = c(1500, 100)) +saem_saemix_dfop_tc_1.5k$so <- saemix::llgq.saemix(saem_saemix_dfop_tc_1.5k$so) +saemix::plot(saem_saemix_dfop_tc_1.5k$so, plot.type = "convergence") +AIC(saem_saemix_dfop_tc_1.5k$so) +AIC(saem_saemix_dfop_tc_1.5k$so, "gq") +intervals(saem_saemix_dfop_tc_1.5k) + +# nlmixr saem +saem_nlmixr_dfop_tc <- nlmixr(nlm_dfop_tc, est = "saem", + control = nlmixr::saemControl(nBurn = 300, nEm = 100, nmc = 9, print = 0)) +intervals(saem_nlmixr_dfop_tc) +summary(saem_nlmixr_dfop_tc) +AIC(saem_nlmixr_dfop_tc$nm) + +saem_nlmixr_dfop_tc_1k <- nlmixr(nlm_dfop_tc, est = "saem", + control = nlmixr::saemControl(nBurn = 1000, nEm = 300, nmc = 9, print = 0)) +intervals(saem_nlmixr_dfop_tc_1k) +summary(saem_nlmixr_dfop_tc_1k) +AIC(saem_nlmixr_dfop_tc_1k$nm) + +focei_nlmixr_dfop_tc <- nlmixr(nlm_dfop_tc, est = "focei") +intervals(focei_nlmixr_dfop_tc) + +AIC(saem_nlmixr_dfop_tc$nm) |