diff options
| -rw-r--r-- | R/mkinfit.R | 4 |
1 files changed, 2 insertions, 2 deletions
diff --git a/R/mkinfit.R b/R/mkinfit.R index 635ec292..2012755f 100644 --- a/R/mkinfit.R +++ b/R/mkinfit.R @@ -60,7 +60,7 @@ mkinfit <- function(mkinmod, observed, defaultpar.names <- setdiff(mkinmod$parms, names(parms.ini))
for (parmname in defaultpar.names) {
# Default values for rate constants, depending on the parameterisation
- if (substr(parmname, 1, 2) == "k_") parms.ini[parmname] = 0.1
+ if (substr(parmname, 1, 2) == "k_") parms.ini[parmname] = 0.1 + runif(1)/1e6
# Default values for rate constants for reversible binding
if (grepl("free_bound$", parmname)) parms.ini[parmname] = 0.1
if (grepl("bound_free$", parmname)) parms.ini[parmname] = 0.02
@@ -115,7 +115,7 @@ mkinfit <- function(mkinmod, observed, solution_type = "analytical"
} else {
if (is.matrix(mkinmod$coefmat)) {
- solution_type = "eigen"
+ solution_type = "eigen"
if (max(observed$value, na.rm = TRUE) < 0.1) {
stop("The combination of small observed values (all < 0.1) and solution_type = eigen is error-prone")
}
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