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Diffstat (limited to 'NEWS.md')
| -rw-r--r-- | NEWS.md | 12 |
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@@ -1,3 +1,15 @@ +# mkin 1.0.5 (unreleased) + +## Mixed-effects models + +- Introduce an interface to nlmixr, supporting estimation methods 'saem' and 'focei': S3 method 'nlmixr.mmkin' using the helper functions 'nlmixr_model' and 'nlmixr_data' to set up nlmixr models for mmkin row objects, with summary and plot methods. + +- Reintroduce the interface to current development versions (not on CRAN) of saemix, in particular the generic function 'saem' with a generator 'saem.mmkin', currently using 'saemix_model' and 'saemix_data', summary and plot methods + +- 'mean_degparms': New argument 'test_log_parms' that makes the function only consider log-transformed parameters where the untransformed parameters pass the t-test for a certain confidence level. This can be used to obtain more plausible starting parameters for the different mixed-effects model backends + +- 'plot.mixed.mmkin': Gains arguments 'test_log_parms' and 'conf.level' + # mkin 1.0.4 (2021-04-20) - All plotting functions setting graphical parameters: Use on.exit() for resetting graphical parameters |