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Diffstat (limited to 'NEWS.md')
| -rw-r--r-- | NEWS.md | 16 |
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@@ -1,3 +1,19 @@ +# mkin 1.1.0 (unreleased) + +## Mixed-effects models + +- Introduce an interface to nlmixr, supporting estimation methods 'saem' and 'focei': S3 method 'nlmixr.mmkin' using the helper functions 'nlmixr_model' and 'nlmixr_data' to set up nlmixr models for mmkin row objects, with summary and plot methods. + +- Reintroduce the interface to current development versions (not on CRAN) of saemix, in particular the generic function 'saem' with a generator 'saem.mmkin', currently using 'saemix_model' and 'saemix_data', summary and plot methods + +- 'mean_degparms': New argument 'test_log_parms' that makes the function only consider log-transformed parameters where the untransformed parameters pass the t-test for a certain confidence level. This can be used to obtain more plausible starting parameters for the different mixed-effects model backends + +- 'plot.mixed.mmkin': Gains arguments 'test_log_parms' and 'conf.level' + +- 'vignettes/web_only/dimethenamid_2018.rmd': Example evaluations of the dimethenamid data. + +- 'intervals': Provide methods of this nlme function for 'nlmixr.mmkin' and 'saem.mmkin' objects. + # mkin 1.0.5 (2021-09-15) - 'dimethenamid_2018': Correct the data for the Borstel soil. The five observations from Staudenmaier (2013) that were previously stored as "Borstel 2" are actually just a subset of the 16 observations in "Borstel 1" which is now simply "Borstel" |