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@@ -114,6 +114,9 @@ or the package vignettes referenced from the `reweight = "obs"` to your call to `mkinfit` and a separate variance componenent for each of the observed variables will be optimised in a second stage after the primary optimisation algorithm has converged. +* When a metabolite decline phase is not described well by SFO kinetics, + either IORE kinetics or SFORB kinetics can be used for the metabolite, + adding one respectively two parameters to the system. ## GUI |