diff options
Diffstat (limited to 'docs/dev/reference/saem.html')
| -rw-r--r-- | docs/dev/reference/saem.html | 90 |
1 files changed, 58 insertions, 32 deletions
diff --git a/docs/dev/reference/saem.html b/docs/dev/reference/saem.html index 59589378..23102df3 100644 --- a/docs/dev/reference/saem.html +++ b/docs/dev/reference/saem.html @@ -74,7 +74,7 @@ Expectation Maximisation algorithm (SAEM)." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-info" data-toggle="tooltip" data-placement="bottom" title="In-development version">0.9.50.4</span> + <span class="version label label-info" data-toggle="tooltip" data-placement="bottom" title="In-development version">1.0.4.9000</span> </span> </div> @@ -158,9 +158,12 @@ Expectation Maximisation algorithm (SAEM).</p> <span class='va'>object</span>, transformations <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"mkin"</span>, <span class='st'>"saemix"</span><span class='op'>)</span>, degparms_start <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/numeric.html'>numeric</a></span><span class='op'>(</span><span class='op'>)</span>, + test_log_parms <span class='op'>=</span> <span class='cn'>FALSE</span>, + conf.level <span class='op'>=</span> <span class='fl'>0.6</span>, solution_type <span class='op'>=</span> <span class='st'>"auto"</span>, control <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>displayProgress <span class='op'>=</span> <span class='cn'>FALSE</span>, print <span class='op'>=</span> <span class='cn'>FALSE</span>, save <span class='op'>=</span> <span class='cn'>FALSE</span>, save.graphs <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span>, + fail_with_errors <span class='op'>=</span> <span class='cn'>TRUE</span>, verbose <span class='op'>=</span> <span class='cn'>FALSE</span>, quiet <span class='op'>=</span> <span class='cn'>FALSE</span>, <span class='va'>...</span> @@ -174,6 +177,7 @@ Expectation Maximisation algorithm (SAEM).</p> solution_type <span class='op'>=</span> <span class='st'>"auto"</span>, transformations <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"mkin"</span>, <span class='st'>"saemix"</span><span class='op'>)</span>, degparms_start <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/numeric.html'>numeric</a></span><span class='op'>(</span><span class='op'>)</span>, + test_log_parms <span class='op'>=</span> <span class='cn'>FALSE</span>, verbose <span class='op'>=</span> <span class='cn'>FALSE</span>, <span class='va'>...</span> <span class='op'>)</span> @@ -206,6 +210,18 @@ SFO or DFOP is used for the parent and there is either no metabolite or one.</p> be used to override the starting values obtained from the 'mmkin' object.</p></td> </tr> <tr> + <th>test_log_parms</th> + <td><p>If TRUE, an attempt is made to use more robust starting +values for population parameters fitted as log parameters in mkin (like +rate constants) by only considering rate constants that pass the t-test +when calculating mean degradation parameters using <a href='nlme_function.html'>mean_degparms</a>.</p></td> + </tr> + <tr> + <th>conf.level</th> + <td><p>Possibility to adjust the required confidence level +for parameter that are tested if requested by 'test_log_parms'.</p></td> + </tr> + <tr> <th>solution_type</th> <td><p>Possibility to specify the solution type in case the automatic choice is not desired</p></td> @@ -215,6 +231,11 @@ automatic choice is not desired</p></td> <td><p>Passed to <a href='https://rdrr.io/pkg/saemix/man/saemix.html'>saemix::saemix</a></p></td> </tr> <tr> + <th>fail_with_errors</th> + <td><p>Should a failure to compute standard errors +from the inverse of the Fisher Information Matrix be a failure?</p></td> + </tr> + <tr> <th>verbose</th> <td><p>Should we print information about created objects of type <a href='https://rdrr.io/pkg/saemix/man/SaemixModel-class.html'>saemix::SaemixModel</a> and <a href='https://rdrr.io/pkg/saemix/man/SaemixData-class.html'>saemix::SaemixData</a>?</p></td> @@ -261,33 +282,36 @@ using <a href='mmkin.html'>mmkin</a>.</p> state.ini <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>100</span><span class='op'>)</span>, fixed_initials <span class='op'>=</span> <span class='st'>"parent"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> <span class='va'>f_saem_p0_fixed</span> <span class='op'><-</span> <span class='fu'>saem</span><span class='op'>(</span><span class='va'>f_mmkin_parent_p0_fixed</span><span class='op'>)</span> </div><div class='output co'>#> Running main SAEM algorithm -#> [1] "Mon Jan 25 14:41:42 2021" +#> [1] "Tue Mar 9 17:34:44 2021" #> .... #> Minimisation finished -#> [1] "Mon Jan 25 14:41:43 2021"</div><div class='input'> +#> [1] "Tue Mar 9 17:34:45 2021"</div><div class='input'> <span class='va'>f_mmkin_parent</span> <span class='op'><-</span> <span class='fu'><a href='mmkin.html'>mmkin</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"FOMC"</span>, <span class='st'>"DFOP"</span><span class='op'>)</span>, <span class='va'>ds</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> <span class='va'>f_saem_sfo</span> <span class='op'><-</span> <span class='fu'>saem</span><span class='op'>(</span><span class='va'>f_mmkin_parent</span><span class='op'>[</span><span class='st'>"SFO"</span>, <span class='op'>]</span><span class='op'>)</span> </div><div class='output co'>#> Running main SAEM algorithm -#> [1] "Mon Jan 25 14:41:45 2021" +#> [1] "Tue Mar 9 17:34:46 2021" #> .... #> Minimisation finished -#> [1] "Mon Jan 25 14:41:46 2021"</div><div class='input'><span class='va'>f_saem_fomc</span> <span class='op'><-</span> <span class='fu'>saem</span><span class='op'>(</span><span class='va'>f_mmkin_parent</span><span class='op'>[</span><span class='st'>"FOMC"</span>, <span class='op'>]</span><span class='op'>)</span> +#> [1] "Tue Mar 9 17:34:48 2021"</div><div class='input'><span class='va'>f_saem_fomc</span> <span class='op'><-</span> <span class='fu'>saem</span><span class='op'>(</span><span class='va'>f_mmkin_parent</span><span class='op'>[</span><span class='st'>"FOMC"</span>, <span class='op'>]</span><span class='op'>)</span> </div><div class='output co'>#> Running main SAEM algorithm -#> [1] "Mon Jan 25 14:41:47 2021" +#> [1] "Tue Mar 9 17:34:48 2021" #> .... #> Minimisation finished -#> [1] "Mon Jan 25 14:41:49 2021"</div><div class='input'><span class='va'>f_saem_dfop</span> <span class='op'><-</span> <span class='fu'>saem</span><span class='op'>(</span><span class='va'>f_mmkin_parent</span><span class='op'>[</span><span class='st'>"DFOP"</span>, <span class='op'>]</span><span class='op'>)</span> +#> [1] "Tue Mar 9 17:34:50 2021"</div><div class='input'><span class='va'>f_saem_dfop</span> <span class='op'><-</span> <span class='fu'>saem</span><span class='op'>(</span><span class='va'>f_mmkin_parent</span><span class='op'>[</span><span class='st'>"DFOP"</span>, <span class='op'>]</span><span class='op'>)</span> </div><div class='output co'>#> Running main SAEM algorithm -#> [1] "Mon Jan 25 14:41:49 2021" +#> [1] "Tue Mar 9 17:34:51 2021" #> .... #> Minimisation finished -#> [1] "Mon Jan 25 14:41:52 2021"</div><div class='input'> +#> [1] "Tue Mar 9 17:34:53 2021"</div><div class='input'> <span class='co'># The returned saem.mmkin object contains an SaemixObject, therefore we can use</span> <span class='co'># functions from saemix</span> <span class='kw'><a href='https://rdrr.io/r/base/library.html'>library</a></span><span class='op'>(</span><span class='va'>saemix</span><span class='op'>)</span> </div><div class='output co'>#> <span class='message'>Package saemix, version 3.1.9000</span> -#> <span class='message'> please direct bugs, questions and feedback to emmanuelle.comets@inserm.fr</span></div><div class='input'><span class='fu'><a href='https://rdrr.io/pkg/saemix/man/compare.saemix.html'>compare.saemix</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span><span class='va'>f_saem_sfo</span><span class='op'>$</span><span class='va'>so</span>, <span class='va'>f_saem_fomc</span><span class='op'>$</span><span class='va'>so</span>, <span class='va'>f_saem_dfop</span><span class='op'>$</span><span class='va'>so</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='error'>Error in compare.saemix(list(f_saem_sfo$so, f_saem_fomc$so, f_saem_dfop$so)): 'compare.saemix' requires at least two models.</span></div><div class='input'><span class='fu'><a href='https://rdrr.io/pkg/saemix/man/plot-SaemixObject-method.html'>plot</a></span><span class='op'>(</span><span class='va'>f_saem_fomc</span><span class='op'>$</span><span class='va'>so</span>, plot.type <span class='op'>=</span> <span class='st'>"convergence"</span><span class='op'>)</span> +#> <span class='message'> please direct bugs, questions and feedback to emmanuelle.comets@inserm.fr</span></div><div class='input'><span class='fu'><a href='https://rdrr.io/pkg/saemix/man/compare.saemix.html'>compare.saemix</a></span><span class='op'>(</span><span class='va'>f_saem_sfo</span><span class='op'>$</span><span class='va'>so</span>, <span class='va'>f_saem_fomc</span><span class='op'>$</span><span class='va'>so</span>, <span class='va'>f_saem_dfop</span><span class='op'>$</span><span class='va'>so</span><span class='op'>)</span> +</div><div class='output co'>#> <span class='message'>Likelihoods calculated by importance sampling</span></div><div class='output co'>#> AIC BIC +#> 1 624.2484 622.2956 +#> 2 467.7096 464.9757 +#> 3 495.4373 491.9222</div><div class='input'><span class='fu'><a href='https://rdrr.io/pkg/saemix/man/plot-SaemixObject-method.html'>plot</a></span><span class='op'>(</span><span class='va'>f_saem_fomc</span><span class='op'>$</span><span class='va'>so</span>, plot.type <span class='op'>=</span> <span class='st'>"convergence"</span><span class='op'>)</span> </div><div class='output co'>#> Plotting convergence plots</div><div class='input'><span class='fu'><a href='https://rdrr.io/pkg/saemix/man/plot-SaemixObject-method.html'>plot</a></span><span class='op'>(</span><span class='va'>f_saem_fomc</span><span class='op'>$</span><span class='va'>so</span>, plot.type <span class='op'>=</span> <span class='st'>"individual.fit"</span><span class='op'>)</span> </div><div class='img'><img src='saem-1.png' alt='' width='700' height='433' /></div><div class='output co'>#> Plotting individual fits</div><div class='input'><span class='fu'><a href='https://rdrr.io/pkg/saemix/man/plot-SaemixObject-method.html'>plot</a></span><span class='op'>(</span><span class='va'>f_saem_fomc</span><span class='op'>$</span><span class='va'>so</span>, plot.type <span class='op'>=</span> <span class='st'>"npde"</span><span class='op'>)</span> </div><div class='img'><img src='saem-2.png' alt='' width='700' height='433' /></div><div class='output co'>#> Simulating data using nsim = 1000 simulated datasets @@ -324,11 +348,13 @@ using <a href='mmkin.html'>mmkin</a>.</p> <span class='va'>f_mmkin_parent_tc</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/update.html'>update</a></span><span class='op'>(</span><span class='va'>f_mmkin_parent</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span><span class='op'>)</span> <span class='va'>f_saem_fomc_tc</span> <span class='op'><-</span> <span class='fu'>saem</span><span class='op'>(</span><span class='va'>f_mmkin_parent_tc</span><span class='op'>[</span><span class='st'>"FOMC"</span>, <span class='op'>]</span><span class='op'>)</span> </div><div class='output co'>#> Running main SAEM algorithm -#> [1] "Mon Jan 25 14:41:55 2021" +#> [1] "Tue Mar 9 17:34:55 2021" #> .... #> Minimisation finished -#> [1] "Mon Jan 25 14:42:00 2021"</div><div class='input'><span class='fu'><a href='https://rdrr.io/pkg/saemix/man/compare.saemix.html'>compare.saemix</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span><span class='va'>f_saem_fomc</span><span class='op'>$</span><span class='va'>so</span>, <span class='va'>f_saem_fomc_tc</span><span class='op'>$</span><span class='va'>so</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='error'>Error in compare.saemix(list(f_saem_fomc$so, f_saem_fomc_tc$so)): 'compare.saemix' requires at least two models.</span></div><div class='input'> +#> [1] "Tue Mar 9 17:35:00 2021"</div><div class='input'><span class='fu'><a href='https://rdrr.io/pkg/saemix/man/compare.saemix.html'>compare.saemix</a></span><span class='op'>(</span><span class='va'>f_saem_fomc</span><span class='op'>$</span><span class='va'>so</span>, <span class='va'>f_saem_fomc_tc</span><span class='op'>$</span><span class='va'>so</span><span class='op'>)</span> +</div><div class='output co'>#> <span class='message'>Likelihoods calculated by importance sampling</span></div><div class='output co'>#> AIC BIC +#> 1 467.7096 464.9757 +#> 2 469.6831 466.5586</div><div class='input'> <span class='va'>sfo_sfo</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"A1"</span><span class='op'>)</span>, A1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span> </div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'><span class='va'>fomc_sfo</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"FOMC"</span>, <span class='st'>"A1"</span><span class='op'>)</span>, @@ -346,15 +372,15 @@ using <a href='mmkin.html'>mmkin</a>.</p> <span class='co'># four minutes</span> <span class='va'>f_saem_sfo_sfo</span> <span class='op'><-</span> <span class='fu'>saem</span><span class='op'>(</span><span class='va'>f_mmkin</span><span class='op'>[</span><span class='st'>"SFO-SFO"</span>, <span class='op'>]</span><span class='op'>)</span> </div><div class='output co'>#> Running main SAEM algorithm -#> [1] "Mon Jan 25 14:42:02 2021" +#> [1] "Tue Mar 9 17:35:02 2021" #> .... #> Minimisation finished -#> [1] "Mon Jan 25 14:42:07 2021"</div><div class='input'><span class='va'>f_saem_dfop_sfo</span> <span class='op'><-</span> <span class='fu'>saem</span><span class='op'>(</span><span class='va'>f_mmkin</span><span class='op'>[</span><span class='st'>"DFOP-SFO"</span>, <span class='op'>]</span><span class='op'>)</span> +#> [1] "Tue Mar 9 17:35:07 2021"</div><div class='input'><span class='va'>f_saem_dfop_sfo</span> <span class='op'><-</span> <span class='fu'>saem</span><span class='op'>(</span><span class='va'>f_mmkin</span><span class='op'>[</span><span class='st'>"DFOP-SFO"</span>, <span class='op'>]</span><span class='op'>)</span> </div><div class='output co'>#> Running main SAEM algorithm -#> [1] "Mon Jan 25 14:42:08 2021" +#> [1] "Tue Mar 9 17:35:07 2021" #> .... #> Minimisation finished -#> [1] "Mon Jan 25 14:42:17 2021"</div><div class='input'><span class='co'># We can use print, plot and summary methods to check the results</span> +#> [1] "Tue Mar 9 17:35:15 2021"</div><div class='input'><span class='co'># We can use print, plot and summary methods to check the results</span> <span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>f_saem_dfop_sfo</span><span class='op'>)</span> </div><div class='output co'>#> Kinetic nonlinear mixed-effects model fit by SAEM #> Structural model: @@ -395,10 +421,10 @@ using <a href='mmkin.html'>mmkin</a>.</p> #> SD.g_qlogis 0.44771 -0.86417 1.7596</div><div class='input'><span class='fu'><a href='https://rdrr.io/pkg/saemix/man/plot-SaemixObject-method.html'>plot</a></span><span class='op'>(</span><span class='va'>f_saem_dfop_sfo</span><span class='op'>)</span> </div><div class='img'><img src='saem-5.png' alt='' width='700' height='433' /></div><div class='input'><span class='fu'><a href='https://rdrr.io/pkg/saemix/man/summary-methods.html'>summary</a></span><span class='op'>(</span><span class='va'>f_saem_dfop_sfo</span>, data <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> </div><div class='output co'>#> saemix version used for fitting: 3.1.9000 -#> mkin version used for pre-fitting: 0.9.50.4 -#> R version used for fitting: 4.0.3 -#> Date of fit: Mon Jan 25 14:42:18 2021 -#> Date of summary: Mon Jan 25 14:42:18 2021 +#> mkin version used for pre-fitting: 1.0.4.9000 +#> R version used for fitting: 4.0.4 +#> Date of fit: Tue Mar 9 17:35:16 2021 +#> Date of summary: Tue Mar 9 17:35:16 2021 #> #> Equations: #> d_parent/dt = - ((k1 * g * exp(-k1 * time) + k2 * (1 - g) * exp(-k2 * @@ -413,7 +439,7 @@ using <a href='mmkin.html'>mmkin</a>.</p> #> #> Model predictions using solution type analytical #> -#> Fitted in 9.954 s using 300, 100 iterations +#> Fitted in 8.668 s using 300, 100 iterations #> #> Variance model: Constant variance #> @@ -489,12 +515,12 @@ using <a href='mmkin.html'>mmkin</a>.</p> #> Dataset 6 parent 3 69.2 71.32042 2.12042 1.883 1.125873 #> Dataset 6 parent 6 58.1 56.45256 -1.64744 1.883 -0.874739 #> Dataset 6 parent 6 56.6 56.45256 -0.14744 1.883 -0.078288 -#> Dataset 6 parent 10 44.4 44.48523 0.08523 1.883 0.045256 +#> Dataset 6 parent 10 44.4 44.48523 0.08523 1.883 0.045257 #> Dataset 6 parent 10 43.4 44.48523 1.08523 1.883 0.576224 #> Dataset 6 parent 20 33.3 29.75774 -3.54226 1.883 -1.880826 #> Dataset 6 parent 20 29.2 29.75774 0.55774 1.883 0.296141 #> Dataset 6 parent 34 17.6 19.35710 1.75710 1.883 0.932966 -#> Dataset 6 parent 34 18.0 19.35710 1.35710 1.883 0.720578 +#> Dataset 6 parent 34 18.0 19.35710 1.35710 1.883 0.720579 #> Dataset 6 parent 55 10.5 10.48443 -0.01557 1.883 -0.008266 #> Dataset 6 parent 55 9.3 10.48443 1.18443 1.883 0.628895 #> Dataset 6 parent 90 4.5 3.78622 -0.71378 1.883 -0.378995 @@ -560,9 +586,9 @@ using <a href='mmkin.html'>mmkin</a>.</p> #> Dataset 8 parent 1 64.9 67.73197 2.83197 1.883 1.503686 #> Dataset 8 parent 1 66.2 67.73197 1.53197 1.883 0.813428 #> Dataset 8 parent 3 43.5 41.58448 -1.91552 1.883 -1.017081 -#> Dataset 8 parent 3 44.1 41.58448 -2.51552 1.883 -1.335661 +#> Dataset 8 parent 3 44.1 41.58448 -2.51552 1.883 -1.335662 #> Dataset 8 parent 8 18.3 19.62286 1.32286 1.883 0.702395 -#> Dataset 8 parent 8 18.1 19.62286 1.52286 1.883 0.808589 +#> Dataset 8 parent 8 18.1 19.62286 1.52286 1.883 0.808588 #> Dataset 8 parent 14 10.2 10.77819 0.57819 1.883 0.306999 #> Dataset 8 parent 14 10.8 10.77819 -0.02181 1.883 -0.011582 #> Dataset 8 parent 27 4.9 3.26977 -1.63023 1.883 -0.865599 @@ -575,13 +601,13 @@ using <a href='mmkin.html'>mmkin</a>.</p> #> Dataset 8 A1 1 7.7 7.61539 -0.08461 1.883 -0.044923 #> Dataset 8 A1 3 15.0 15.47954 0.47954 1.883 0.254622 #> Dataset 8 A1 3 15.1 15.47954 0.37954 1.883 0.201525 -#> Dataset 8 A1 8 21.2 20.22616 -0.97384 1.883 -0.517076 +#> Dataset 8 A1 8 21.2 20.22616 -0.97384 1.883 -0.517075 #> Dataset 8 A1 8 21.1 20.22616 -0.87384 1.883 -0.463979 #> Dataset 8 A1 14 19.7 20.00067 0.30067 1.883 0.159645 #> Dataset 8 A1 14 18.9 20.00067 1.10067 1.883 0.584419 -#> Dataset 8 A1 27 17.5 16.38142 -1.11858 1.883 -0.593929 -#> Dataset 8 A1 27 15.9 16.38142 0.48142 1.883 0.255619 -#> Dataset 8 A1 48 9.5 10.25357 0.75357 1.883 0.400123 +#> Dataset 8 A1 27 17.5 16.38142 -1.11858 1.883 -0.593928 +#> Dataset 8 A1 27 15.9 16.38142 0.48142 1.883 0.255620 +#> Dataset 8 A1 48 9.5 10.25357 0.75357 1.883 0.400124 #> Dataset 8 A1 48 9.8 10.25357 0.45357 1.883 0.240833 #> Dataset 8 A1 70 6.2 5.95728 -0.24272 1.883 -0.128878 #> Dataset 8 A1 70 6.1 5.95728 -0.14272 1.883 -0.075781 @@ -622,7 +648,7 @@ using <a href='mmkin.html'>mmkin</a>.</p> #> Dataset 9 A1 91 10.0 10.09177 0.09177 1.883 0.048727 #> Dataset 9 A1 91 9.5 10.09177 0.59177 1.883 0.314211 #> Dataset 9 A1 120 9.1 7.91379 -1.18621 1.883 -0.629841 -#> Dataset 9 A1 120 9.0 7.91379 -1.08621 1.883 -0.576745 +#> Dataset 9 A1 120 9.0 7.91379 -1.08621 1.883 -0.576744 #> Dataset 10 parent 0 96.1 93.65257 -2.44743 1.883 -1.299505 #> Dataset 10 parent 0 94.3 93.65257 -0.64743 1.883 -0.343763 #> Dataset 10 parent 8 73.9 77.85906 3.95906 1.883 2.102132 |