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+ <h1> Single First-Order Reversible Binding kinetics </h1>
+ </div>
+
+
+ <p>Function describing the solution of the differential equations describing
+ the kinetic model with first-order terms for a two-way transfer from a free
+ to a bound fraction, and a first-order degradation term for the free
+ fraction. The initial condition is a defined amount in the free fraction and
+ no substance in the bound fraction.</p>
+
+
+ <pre><span class='fu'>SFORB.solution</span>(<span class='no'>t</span>, <span class='no'>parent.0</span>, <span class='no'>k_12</span>, <span class='no'>k_21</span>, <span class='no'>k_1output</span>)</pre>
+
+ <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a> Arguments</h2>
+ <dl class="dl-horizontal">
+ <dt>t</dt>
+ <dd> Time. </dd>
+ <dt>parent.0</dt>
+ <dd> Starting value for the response variable at time zero. </dd>
+ <dt>k_12</dt>
+ <dd> Kinetic constant describing transfer from free to bound. </dd>
+ <dt>k_21</dt>
+ <dd> Kinetic constant describing transfer from bound to free. </dd>
+ <dt>k_1output</dt>
+ <dd> Kinetic constant describing degradation of the free fraction. </dd>
+ </dl>
+
+ <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2>
+
+ <p>The value of the response variable, which is the sum of free and bound
+ fractions at time <code>t</code>.</p>
+
+ <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2>
+
+ <p>FOCUS (2006) &#8220;Guidance Document on Estimating Persistence and
+ Degradation Kinetics from Environmental Fate Studies on Pesticides in EU
+ Registration&#8221; Report of the FOCUS Work Group on Degradation Kinetics,
+ EC Document Reference Sanco/10058/2005 version 2.0, 434 pp,
+ <a href = 'http://focus.jrc.ec.europa.eu/dk'>http://focus.jrc.ec.europa.eu/dk</a></p>
+
+
+ <h2 class="hasAnchor" id="examples">
+ <a class="anchor" href="#examples"></a>
+ Examples
+ </h2>
+ <pre class="examples"><div class='input'> <span class='co'>## Not run: plot(function(x) SFORB.solution(x, 100, 0.5, 2, 3), 0, 2)</span></div></pre>
+ </div>
+ <div class="col-md-3 hidden-xs hidden-sm" id="sidebar">
+ <h2>Contents</h2>
+ <ul class="nav nav-pills nav-stacked">
+ <li><a href="#arguments">Arguments</a></li>
+
+ <li><a href="#value">Value</a></li>
+
+ <li><a href="#references">References</a></li>
+
+ <li><a href="#examples">Examples</a></li>
+ </ul>
+
+ </div>
+</div>
+
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