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-<meta property="og:description" content="Compare two mkinfit models based on their likelihood. If two fitted
+<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Likelihood ratio test for mkinfit models — lrtest.mkinfit • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Likelihood ratio test for mkinfit models — lrtest.mkinfit"><meta property="og:description" content="Compare two mkinfit models based on their likelihood. If two fitted
mkinfit objects are given as arguments, it is checked if they have been
fitted to the same data. It is the responsibility of the user to make sure
that the models are nested, i.e. one of them has less degrees of freedom
-and can be expressed by fixing the parameters of the other." />
-
-
-
-
-<!-- mathjax -->
-<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script>
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-
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+and can be expressed by fixing the parameters of the other."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
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@@ -76,13 +21,12 @@ and can be expressed by fixing the parameters of the other." />
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<a class="navbar-link" href="../index.html">mkin</a>
- <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span>
+ <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span>
</span>
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+ <ul class="nav navbar-nav"><li>
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@@ -91,8 +35,7 @@ and can be expressed by fixing the parameters of the other." />
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+ <ul class="dropdown-menu" role="menu"><li>
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<li>
@@ -102,6 +45,9 @@ and can be expressed by fixing the parameters of the other." />
<a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a>
</li>
<li>
+ <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a>
+ </li>
+ <li>
<a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a>
</li>
<li>
@@ -116,34 +62,27 @@ and can be expressed by fixing the parameters of the other." />
<li>
<a href="../articles/web_only/benchmarks.html">Some benchmark timings</a>
</li>
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-</li>
+ </ul></li>
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<a href="../news/index.html">News</a>
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- <ul class="nav navbar-nav navbar-right">
- <li>
- <a href="https://github.com/jranke/mkin/">
+ </ul><ul class="nav navbar-nav navbar-right"><li>
+ <a href="https://github.com/jranke/mkin/" class="external-link">
<span class="fab fa-github fa-lg"></span>
</a>
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<div class="page-header">
<h1>Likelihood ratio test for mkinfit models</h1>
- <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/lrtest.mkinfit.R'><code>R/lrtest.mkinfit.R</code></a></small>
+ <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/lrtest.mkinfit.R" class="external-link"><code>R/lrtest.mkinfit.R</code></a></small>
<div class="hidden name"><code>lrtest.mkinfit.Rd</code></div>
</div>
@@ -155,115 +94,112 @@ that the models are nested, i.e. one of them has less degrees of freedom
and can be expressed by fixing the parameters of the other.</p>
</div>
- <pre class="usage"><span class='co'># S3 method for mkinfit</span>
-<span class='fu'><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a></span><span class='op'>(</span><span class='va'>object</span>, object_2 <span class='op'>=</span> <span class='cn'>NULL</span>, <span class='va'>...</span><span class='op'>)</span>
-
-<span class='co'># S3 method for mmkin</span>
-<span class='fu'><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a></span><span class='op'>(</span><span class='va'>object</span>, <span class='va'>...</span><span class='op'>)</span></pre>
-
- <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2>
- <table class="ref-arguments">
- <colgroup><col class="name" /><col class="desc" /></colgroup>
- <tr>
- <th>object</th>
- <td><p>An <code><a href='mkinfit.html'>mkinfit</a></code> object, or an <code><a href='mmkin.html'>mmkin</a></code> column
-object containing two fits to the same data.</p></td>
- </tr>
- <tr>
- <th>object_2</th>
- <td><p>Optionally, another mkinfit object fitted to the same data.</p></td>
- </tr>
- <tr>
- <th>...</th>
- <td><p>Argument to <code><a href='mkinfit.html'>mkinfit</a></code>, passed to
-<code><a href='update.mkinfit.html'>update.mkinfit</a></code> for creating the alternative fitted object.</p></td>
- </tr>
- </table>
+ <div id="ref-usage">
+ <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for mkinfit</span>
+<span class="fu"><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a></span><span class="op">(</span><span class="va">object</span>, object_2 <span class="op">=</span> <span class="cn">NULL</span>, <span class="va">...</span><span class="op">)</span>
- <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2>
+<span class="co"># S3 method for mmkin</span>
+<span class="fu"><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a></span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span><span class="op">)</span></code></pre></div>
+ </div>
+ <div id="arguments">
+ <h2>Arguments</h2>
+ <dl><dt>object</dt>
+<dd><p>An <code><a href="mkinfit.html">mkinfit</a></code> object, or an <code><a href="mmkin.html">mmkin</a></code> column
+object containing two fits to the same data.</p></dd>
+<dt>object_2</dt>
+<dd><p>Optionally, another mkinfit object fitted to the same data.</p></dd>
+<dt>...</dt>
+<dd><p>Argument to <code><a href="mkinfit.html">mkinfit</a></code>, passed to
+<code><a href="update.mkinfit.html">update.mkinfit</a></code> for creating the alternative fitted object.</p></dd>
+</dl></div>
+ <div id="details">
+ <h2>Details</h2>
<p>Alternatively, an argument to mkinfit can be given which is then passed
-to <code><a href='update.mkinfit.html'>update.mkinfit</a></code> to obtain the alternative model.</p>
-<p>The comparison is then made by the <code><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest.default</a></code>
+to <code><a href="update.mkinfit.html">update.mkinfit</a></code> to obtain the alternative model.</p>
+<p>The comparison is then made by the <code><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest.default</a></code>
method from the lmtest package. The model with the higher number of fitted
parameters (alternative hypothesis) is listed first, then the model with the
lower number of fitted parameters (null hypothesis).</p>
+ </div>
- <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2>
- <pre class="examples"><div class='input'><span class='co'># \dontrun{</span>
-<span class='va'>test_data</span> <span class='op'>&lt;-</span> <span class='fu'><a href='https://rdrr.io/r/base/subset.html'>subset</a></span><span class='op'>(</span><span class='va'>synthetic_data_for_UBA_2014</span><span class='op'>[[</span><span class='fl'>12</span><span class='op'>]</span><span class='op'>]</span><span class='op'>$</span><span class='va'>data</span>, <span class='va'>name</span> <span class='op'>==</span> <span class='st'>"parent"</span><span class='op'>)</span>
-<span class='va'>sfo_fit</span> <span class='op'>&lt;-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='va'>test_data</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span>
-<span class='va'>dfop_fit</span> <span class='op'>&lt;-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"DFOP"</span>, <span class='va'>test_data</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span>
-<span class='fu'><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a></span><span class='op'>(</span><span class='va'>dfop_fit</span>, <span class='va'>sfo_fit</span><span class='op'>)</span>
-</div><div class='output co'>#&gt; Likelihood ratio test
-#&gt;
-#&gt; Model 1: DFOP with error model const
-#&gt; Model 2: SFO with error model const
-#&gt; #Df LogLik Df Chisq Pr(&gt;Chisq)
-#&gt; 1 5 -42.453
-#&gt; 2 3 -63.954 -2 43.002 4.594e-10 ***
-#&gt; ---
-#&gt; Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</div><div class='input'><span class='fu'><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a></span><span class='op'>(</span><span class='va'>sfo_fit</span>, <span class='va'>dfop_fit</span><span class='op'>)</span>
-</div><div class='output co'>#&gt; Likelihood ratio test
-#&gt;
-#&gt; Model 1: DFOP with error model const
-#&gt; Model 2: SFO with error model const
-#&gt; #Df LogLik Df Chisq Pr(&gt;Chisq)
-#&gt; 1 5 -42.453
-#&gt; 2 3 -63.954 -2 43.002 4.594e-10 ***
-#&gt; ---
-#&gt; Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</div><div class='input'>
-<span class='co'># The following two examples are commented out as they fail during</span>
-<span class='co'># generation of the static help pages by pkgdown</span>
-<span class='co'>#lrtest(dfop_fit, error_model = "tc")</span>
-<span class='co'>#lrtest(dfop_fit, fixed_parms = c(k2 = 0))</span>
-
-<span class='co'># However, this equivalent syntax also works for static help pages</span>
-<span class='fu'><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a></span><span class='op'>(</span><span class='va'>dfop_fit</span>, <span class='fu'><a href='https://rdrr.io/r/stats/update.html'>update</a></span><span class='op'>(</span><span class='va'>dfop_fit</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span><span class='op'>)</span><span class='op'>)</span>
-</div><div class='output co'>#&gt; Likelihood ratio test
-#&gt;
-#&gt; Model 1: DFOP with error model tc
-#&gt; Model 2: DFOP with error model const
-#&gt; #Df LogLik Df Chisq Pr(&gt;Chisq)
-#&gt; 1 6 -34.587
-#&gt; 2 5 -42.453 -1 15.731 7.302e-05 ***
-#&gt; ---
-#&gt; Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</div><div class='input'><span class='fu'><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a></span><span class='op'>(</span><span class='va'>dfop_fit</span>, <span class='fu'><a href='https://rdrr.io/r/stats/update.html'>update</a></span><span class='op'>(</span><span class='va'>dfop_fit</span>, fixed_parms <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k2 <span class='op'>=</span> <span class='fl'>0</span><span class='op'>)</span><span class='op'>)</span><span class='op'>)</span>
-</div><div class='output co'>#&gt; Likelihood ratio test
-#&gt;
-#&gt; Model 1: DFOP with error model const
-#&gt; Model 2: DFOP with error model const and fixed parameter(s) k2
-#&gt; #Df LogLik Df Chisq Pr(&gt;Chisq)
-#&gt; 1 5 -42.453
-#&gt; 2 4 -57.340 -1 29.776 4.851e-08 ***
-#&gt; ---
-#&gt; Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</div><div class='input'><span class='co'># }</span>
-</div></pre>
+ <div id="ref-examples">
+ <h2>Examples</h2>
+ <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="co"># \dontrun{</span></span>
+<span class="r-in"><span class="va">test_data</span> <span class="op">&lt;-</span> <span class="fu"><a href="https://rdrr.io/r/base/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">synthetic_data_for_UBA_2014</span><span class="op">[[</span><span class="fl">12</span><span class="op">]</span><span class="op">]</span><span class="op">$</span><span class="va">data</span>, <span class="va">name</span> <span class="op">==</span> <span class="st">"parent"</span><span class="op">)</span></span>
+<span class="r-in"><span class="va">sfo_fit</span> <span class="op">&lt;-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="va">test_data</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span>
+<span class="r-in"><span class="va">dfop_fit</span> <span class="op">&lt;-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="va">test_data</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span>
+<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a></span><span class="op">(</span><span class="va">dfop_fit</span>, <span class="va">sfo_fit</span><span class="op">)</span></span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> Likelihood ratio test</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> </span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> Model 1: DFOP with error model const</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> Model 2: SFO with error model const</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> #Df LogLik Df Chisq Pr(&gt;Chisq) </span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> 1 5 -42.453 </span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> 2 3 -63.954 -2 43.002 4.594e-10 ***</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> ---</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</span>
+<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a></span><span class="op">(</span><span class="va">sfo_fit</span>, <span class="va">dfop_fit</span><span class="op">)</span></span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> Likelihood ratio test</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> </span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> Model 1: DFOP with error model const</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> Model 2: SFO with error model const</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> #Df LogLik Df Chisq Pr(&gt;Chisq) </span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> 1 5 -42.453 </span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> 2 3 -63.954 -2 43.002 4.594e-10 ***</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> ---</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</span>
+<span class="r-in"></span>
+<span class="r-in"><span class="co"># The following two examples are commented out as they fail during</span></span>
+<span class="r-in"><span class="co"># generation of the static help pages by pkgdown</span></span>
+<span class="r-in"><span class="co">#lrtest(dfop_fit, error_model = "tc")</span></span>
+<span class="r-in"><span class="co">#lrtest(dfop_fit, fixed_parms = c(k2 = 0))</span></span>
+<span class="r-in"></span>
+<span class="r-in"><span class="co"># However, this equivalent syntax also works for static help pages</span></span>
+<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a></span><span class="op">(</span><span class="va">dfop_fit</span>, <span class="fu"><a href="https://rdrr.io/r/stats/update.html" class="external-link">update</a></span><span class="op">(</span><span class="va">dfop_fit</span>, error_model <span class="op">=</span> <span class="st">"tc"</span><span class="op">)</span><span class="op">)</span></span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> Likelihood ratio test</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> </span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> Model 1: DFOP with error model tc</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> Model 2: DFOP with error model const</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> #Df LogLik Df Chisq Pr(&gt;Chisq) </span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> 1 6 -34.587 </span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> 2 5 -42.453 -1 15.731 7.302e-05 ***</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> ---</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</span>
+<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a></span><span class="op">(</span><span class="va">dfop_fit</span>, <span class="fu"><a href="https://rdrr.io/r/stats/update.html" class="external-link">update</a></span><span class="op">(</span><span class="va">dfop_fit</span>, fixed_parms <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k2 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span><span class="op">)</span><span class="op">)</span></span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> Likelihood ratio test</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> </span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> Model 1: DFOP with error model const</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> Model 2: DFOP with error model const and fixed parameter(s) k2</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> #Df LogLik Df Chisq Pr(&gt;Chisq) </span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> 1 5 -42.453 </span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> 2 4 -57.340 -1 29.776 4.851e-08 ***</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> ---</span>
+<span class="r-out co"><span class="r-pr">#&gt;</span> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</span>
+<span class="r-in"><span class="co"># }</span></span>
+</code></pre></div>
+ </div>
</div>
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