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concentrations (TWAs) for kinetic models fitted with mkinfit.
Currently, only calculations for the parent are implemented for the SFO,
FOMC, DFOP and HS models, using the analytical formulas given in the PEC
-soil section of the FOCUS guidance."><title>Function to calculate maximum time weighted average concentrations from
-kinetic models fitted with mkinfit — max_twa_parent • mkin</title><script src="../deps/jquery-3.6.0/jquery-3.6.0.min.js"></script><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><link href="../deps/bootstrap-5.2.2/bootstrap.min.css" rel="stylesheet"><script src="../deps/bootstrap-5.2.2/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Function to calculate maximum time weighted average concentrations from
-kinetic models fitted with mkinfit — max_twa_parent"><meta property="og:description" content="This function calculates maximum moving window time weighted average
+soil section of the FOCUS guidance."><meta property="og:description" content="This function calculates maximum moving window time weighted average
concentrations (TWAs) for kinetic models fitted with mkinfit.
Currently, only calculations for the parent are implemented for the SFO,
FOMC, DFOP and HS models, using the analytical formulas given in the PEC
-soil section of the FOCUS guidance."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
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- <img src="" class="logo" alt=""><h1>Function to calculate maximum time weighted average concentrations from
-kinetic models fitted with mkinfit</h1>
+
+ <h1>Function to calculate maximum time weighted average concentrations from kinetic models fitted with mkinfit</h1>
<small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/max_twa_parent.R" class="external-link"><code>R/max_twa_parent.R</code></a></small>
<div class="d-none name"><code>max_twa_parent.Rd</code></div>
</div>
@@ -107,59 +91,59 @@ soil section of the FOCUS guidance.</p>
<div class="section level2">
<h2 id="arguments">Arguments<a class="anchor" aria-label="anchor" href="#arguments"></a></h2>
- <dl><dt>fit</dt>
+
+
+<dl><dt id="arg-fit">fit<a class="anchor" aria-label="anchor" href="#arg-fit"></a></dt>
<dd><p>An object of class <code><a href="mkinfit.html">mkinfit</a></code>.</p></dd>
-<dt>windows</dt>
+<dt id="arg-windows">windows<a class="anchor" aria-label="anchor" href="#arg-windows"></a></dt>
<dd><p>The width of the time windows for which the TWAs should be
calculated.</p></dd>
-<dt>M0</dt>
+<dt id="arg-m-">M0<a class="anchor" aria-label="anchor" href="#arg-m-"></a></dt>
<dd><p>The initial concentration for which the maximum time weighted
average over the decline curve should be calculated. The default is to use
a value of 1, which means that a relative maximum time weighted average
factor (f_twa) is calculated.</p></dd>
-<dt>k</dt>
+<dt id="arg-k">k<a class="anchor" aria-label="anchor" href="#arg-k"></a></dt>
<dd><p>The rate constant in the case of SFO kinetics.</p></dd>
-<dt>t</dt>
+<dt id="arg-t">t<a class="anchor" aria-label="anchor" href="#arg-t"></a></dt>
<dd><p>The width of the time window.</p></dd>
-<dt>alpha</dt>
+<dt id="arg-alpha">alpha<a class="anchor" aria-label="anchor" href="#arg-alpha"></a></dt>
<dd><p>Parameter of the FOMC model.</p></dd>
-<dt>beta</dt>
+<dt id="arg-beta">beta<a class="anchor" aria-label="anchor" href="#arg-beta"></a></dt>
<dd><p>Parameter of the FOMC model.</p></dd>
-<dt>k1</dt>
+<dt id="arg-k-">k1<a class="anchor" aria-label="anchor" href="#arg-k-"></a></dt>
<dd><p>The first rate constant of the DFOP or the HS kinetics.</p></dd>
-<dt>k2</dt>
+<dt id="arg-k-">k2<a class="anchor" aria-label="anchor" href="#arg-k-"></a></dt>
<dd><p>The second rate constant of the DFOP or the HS kinetics.</p></dd>
-<dt>g</dt>
+<dt id="arg-g">g<a class="anchor" aria-label="anchor" href="#arg-g"></a></dt>
<dd><p>Parameter of the DFOP model.</p></dd>
-<dt>tb</dt>
+<dt id="arg-tb">tb<a class="anchor" aria-label="anchor" href="#arg-tb"></a></dt>
<dd><p>Parameter of the HS model.</p></dd>
</dl></div>
<div class="section level2">
<h2 id="value">Value<a class="anchor" aria-label="anchor" href="#value"></a></h2>
-
-
-<p>For <code>max_twa_parent</code>, a numeric vector, named using the
+ <p>For <code>max_twa_parent</code>, a numeric vector, named using the
<code>windows</code> argument. For the other functions, a numeric vector of
length one (also known as 'a number').</p>
</div>
@@ -186,23 +170,23 @@ EC Document Reference Sanco/10058/2005 version 2.0, 434 pp,
<span class="r-in"><span></span></span>
</code></pre></div>
</div>
- </main><aside class="col-md-3"><nav id="toc"><h2>On this page</h2>
+ </main><aside class="col-md-3"><nav id="toc" aria-label="Table of contents"><h2>On this page</h2>
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+ <p>Developed by Johannes Ranke.</p>
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