diff options
Diffstat (limited to 'docs/reference')
144 files changed, 28110 insertions, 12575 deletions
diff --git a/docs/reference/AIC.mmkin.html b/docs/reference/AIC.mmkin.html index fbc90802..35becede 100644 --- a/docs/reference/AIC.mmkin.html +++ b/docs/reference/AIC.mmkin.html @@ -1,68 +1,13 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Calculate the AIC for a column of an mmkin object — AIC.mmkin • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Calculate the AIC for a column of an mmkin object — AIC.mmkin" /> -<meta property="og:description" content="Provides a convenient way to compare different kinetic models fitted to the -same dataset." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Calculate the AIC for a column of an mmkin object — AIC.mmkin • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Calculate the AIC for a column of an mmkin object — AIC.mmkin"><meta property="og:description" content="Provides a convenient way to compare different kinetic models fitted to the +same dataset."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -73,13 +18,12 @@ same dataset." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -88,8 +32,7 @@ same dataset." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -99,6 +42,9 @@ same dataset." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -113,34 +59,27 @@ same dataset." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Calculate the AIC for a column of an mmkin object</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/AIC.mmkin.R'><code>R/AIC.mmkin.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/AIC.mmkin.R" class="external-link"><code>R/AIC.mmkin.R</code></a></small> <div class="hidden name"><code>AIC.mmkin.Rd</code></div> </div> @@ -149,102 +88,103 @@ same dataset." /> same dataset.</p> </div> - <pre class="usage"><span class='co'># S3 method for mmkin</span> -<span class='fu'><a href='https://rdrr.io/r/stats/AIC.html'>AIC</a></span><span class='op'>(</span><span class='va'>object</span>, <span class='va'>...</span>, k <span class='op'>=</span> <span class='fl'>2</span><span class='op'>)</span> - -<span class='co'># S3 method for mmkin</span> -<span class='fu'><a href='https://rdrr.io/r/stats/AIC.html'>BIC</a></span><span class='op'>(</span><span class='va'>object</span>, <span class='va'>...</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>An object of class <code><a href='mmkin.html'>mmkin</a></code>, containing only one -column.</p></td> - </tr> - <tr> - <th>...</th> - <td><p>For compatibility with the generic method</p></td> - </tr> - <tr> - <th>k</th> - <td><p>As in the generic method</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for mmkin</span> +<span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">AIC</a></span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span>, k <span class="op">=</span> <span class="fl">2</span><span class="op">)</span> + +<span class="co"># S3 method for mmkin</span> +<span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">BIC</a></span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>An object of class <code><a href="mmkin.html">mmkin</a></code>, containing only one +column.</p></dd> +<dt>...</dt> +<dd><p>For compatibility with the generic method</p></dd> +<dt>k</dt> +<dd><p>As in the generic method</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>As in the generic method (a numeric value for single fits, or a dataframe if there are several fits in the column).</p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> - <span class='co'># skip, as it takes > 10 s on winbuilder</span> - <span class='va'>f</span> <span class='op'><-</span> <span class='fu'><a href='mmkin.html'>mmkin</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"FOMC"</span>, <span class='st'>"DFOP"</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span><span class='st'>"FOCUS A"</span> <span class='op'>=</span> <span class='va'>FOCUS_2006_A</span>, - <span class='st'>"FOCUS C"</span> <span class='op'>=</span> <span class='va'>FOCUS_2006_C</span><span class='op'>)</span>, cores <span class='op'>=</span> <span class='fl'>1</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - <span class='co'># We get a warning because the FOMC model does not converge for the</span> - <span class='co'># FOCUS A dataset, as it is well described by SFO</span> - - <span class='fu'><a href='https://rdrr.io/r/stats/AIC.html'>AIC</a></span><span class='op'>(</span><span class='va'>f</span><span class='op'>[</span><span class='st'>"SFO"</span>, <span class='st'>"FOCUS A"</span><span class='op'>]</span><span class='op'>)</span> <span class='co'># We get a single number for a single fit</span> -</div><div class='output co'>#> [1] 55.28197</div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/stats/AIC.html'>AIC</a></span><span class='op'>(</span><span class='va'>f</span><span class='op'>[[</span><span class='st'>"SFO"</span>, <span class='st'>"FOCUS A"</span><span class='op'>]</span><span class='op'>]</span><span class='op'>)</span> <span class='co'># or when extracting an mkinfit object</span> -</div><div class='output co'>#> [1] 55.28197</div><div class='input'> - <span class='co'># For FOCUS A, the models fit almost equally well, so the higher the number</span> - <span class='co'># of parameters, the higher (worse) the AIC</span> - <span class='fu'><a href='https://rdrr.io/r/stats/AIC.html'>AIC</a></span><span class='op'>(</span><span class='va'>f</span><span class='op'>[</span>, <span class='st'>"FOCUS A"</span><span class='op'>]</span><span class='op'>)</span> -</div><div class='output co'>#> df AIC -#> SFO 3 55.28197 -#> FOMC 4 57.28222 -#> DFOP 5 59.28197</div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/stats/AIC.html'>AIC</a></span><span class='op'>(</span><span class='va'>f</span><span class='op'>[</span>, <span class='st'>"FOCUS A"</span><span class='op'>]</span>, k <span class='op'>=</span> <span class='fl'>0</span><span class='op'>)</span> <span class='co'># If we do not penalize additional parameters, we get nearly the same</span> -</div><div class='output co'>#> df AIC -#> SFO 3 49.28197 -#> FOMC 4 49.28222 -#> DFOP 5 49.28197</div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/stats/AIC.html'>BIC</a></span><span class='op'>(</span><span class='va'>f</span><span class='op'>[</span>, <span class='st'>"FOCUS A"</span><span class='op'>]</span><span class='op'>)</span> <span class='co'># Comparing the BIC gives a very similar picture</span> -</div><div class='output co'>#> df BIC -#> SFO 3 55.52030 -#> FOMC 4 57.59999 -#> DFOP 5 59.67918</div><div class='input'> - <span class='co'># For FOCUS C, the more complex models fit better</span> - <span class='fu'><a href='https://rdrr.io/r/stats/AIC.html'>AIC</a></span><span class='op'>(</span><span class='va'>f</span><span class='op'>[</span>, <span class='st'>"FOCUS C"</span><span class='op'>]</span><span class='op'>)</span> -</div><div class='output co'>#> df AIC -#> SFO 3 59.29336 -#> FOMC 4 44.68652 -#> DFOP 5 29.02372</div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/stats/AIC.html'>BIC</a></span><span class='op'>(</span><span class='va'>f</span><span class='op'>[</span>, <span class='st'>"FOCUS C"</span><span class='op'>]</span><span class='op'>)</span> -</div><div class='output co'>#> df BIC -#> SFO 3 59.88504 -#> FOMC 4 45.47542 -#> DFOP 5 30.00984</div><div class='input'> - -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"> <span class="co"># skip, as it takes > 10 s on winbuilder</span></span> +<span class="r-in"> <span class="va">f</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"FOMC"</span>, <span class="st">"DFOP"</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="st">"FOCUS A"</span> <span class="op">=</span> <span class="va">FOCUS_2006_A</span>,</span> +<span class="r-in"> <span class="st">"FOCUS C"</span> <span class="op">=</span> <span class="va">FOCUS_2006_C</span><span class="op">)</span>, cores <span class="op">=</span> <span class="fl">1</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="co"># We get a warning because the FOMC model does not converge for the</span></span> +<span class="r-in"> <span class="co"># FOCUS A dataset, as it is well described by SFO</span></span> +<span class="r-in"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">AIC</a></span><span class="op">(</span><span class="va">f</span><span class="op">[</span><span class="st">"SFO"</span>, <span class="st">"FOCUS A"</span><span class="op">]</span><span class="op">)</span> <span class="co"># We get a single number for a single fit</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 55.28197</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">AIC</a></span><span class="op">(</span><span class="va">f</span><span class="op">[[</span><span class="st">"SFO"</span>, <span class="st">"FOCUS A"</span><span class="op">]</span><span class="op">]</span><span class="op">)</span> <span class="co"># or when extracting an mkinfit object</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 55.28197</span> +<span class="r-in"></span> +<span class="r-in"> <span class="co"># For FOCUS A, the models fit almost equally well, so the higher the number</span></span> +<span class="r-in"> <span class="co"># of parameters, the higher (worse) the AIC</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">AIC</a></span><span class="op">(</span><span class="va">f</span><span class="op">[</span>, <span class="st">"FOCUS A"</span><span class="op">]</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> df AIC</span> +<span class="r-out co"><span class="r-pr">#></span> SFO 3 55.28197</span> +<span class="r-out co"><span class="r-pr">#></span> FOMC 4 57.28222</span> +<span class="r-out co"><span class="r-pr">#></span> DFOP 5 59.28197</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">AIC</a></span><span class="op">(</span><span class="va">f</span><span class="op">[</span>, <span class="st">"FOCUS A"</span><span class="op">]</span>, k <span class="op">=</span> <span class="fl">0</span><span class="op">)</span> <span class="co"># If we do not penalize additional parameters, we get nearly the same</span></span> +<span class="r-out co"><span class="r-pr">#></span> df AIC</span> +<span class="r-out co"><span class="r-pr">#></span> SFO 3 49.28197</span> +<span class="r-out co"><span class="r-pr">#></span> FOMC 4 49.28222</span> +<span class="r-out co"><span class="r-pr">#></span> DFOP 5 49.28197</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">BIC</a></span><span class="op">(</span><span class="va">f</span><span class="op">[</span>, <span class="st">"FOCUS A"</span><span class="op">]</span><span class="op">)</span> <span class="co"># Comparing the BIC gives a very similar picture</span></span> +<span class="r-out co"><span class="r-pr">#></span> df BIC</span> +<span class="r-out co"><span class="r-pr">#></span> SFO 3 55.52030</span> +<span class="r-out co"><span class="r-pr">#></span> FOMC 4 57.59999</span> +<span class="r-out co"><span class="r-pr">#></span> DFOP 5 59.67918</span> +<span class="r-in"></span> +<span class="r-in"> <span class="co"># For FOCUS C, the more complex models fit better</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">AIC</a></span><span class="op">(</span><span class="va">f</span><span class="op">[</span>, <span class="st">"FOCUS C"</span><span class="op">]</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> df AIC</span> +<span class="r-out co"><span class="r-pr">#></span> SFO 3 59.29336</span> +<span class="r-out co"><span class="r-pr">#></span> FOMC 4 44.68652</span> +<span class="r-out co"><span class="r-pr">#></span> DFOP 5 29.02372</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">BIC</a></span><span class="op">(</span><span class="va">f</span><span class="op">[</span>, <span class="st">"FOCUS C"</span><span class="op">]</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> df BIC</span> +<span class="r-out co"><span class="r-pr">#></span> SFO 3 59.88504</span> +<span class="r-out co"><span class="r-pr">#></span> FOMC 4 45.47542</span> +<span class="r-out co"><span class="r-pr">#></span> DFOP 5 30.00984</span> +<span class="r-in"> </span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/CAKE_export.html b/docs/reference/CAKE_export.html index 05cd04a7..d36f5ed9 100644 --- a/docs/reference/CAKE_export.html +++ b/docs/reference/CAKE_export.html @@ -1,68 +1,13 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Export a list of datasets format to a CAKE study file — CAKE_export • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Export a list of datasets format to a CAKE study file — CAKE_export" /> -<meta property="og:description" content="In addition to the datasets, the pathways in the degradation model can be -specified as well." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Export a list of datasets format to a CAKE study file — CAKE_export • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Export a list of datasets format to a CAKE study file — CAKE_export"><meta property="og:description" content="In addition to the datasets, the pathways in the degradation model can be +specified as well."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -73,13 +18,12 @@ specified as well." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -88,8 +32,7 @@ specified as well." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -99,6 +42,9 @@ specified as well." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -113,34 +59,27 @@ specified as well." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Export a list of datasets format to a CAKE study file</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/CAKE_export.R'><code>R/CAKE_export.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/CAKE_export.R" class="external-link"><code>R/CAKE_export.R</code></a></small> <div class="hidden name"><code>CAKE_export.Rd</code></div> </div> @@ -149,116 +88,88 @@ specified as well." /> specified as well.</p> </div> - <pre class="usage"><span class='fu'>CAKE_export</span><span class='op'>(</span> - <span class='va'>ds</span>, - map <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='st'>"Parent"</span><span class='op'>)</span>, - links <span class='op'>=</span> <span class='cn'>NA</span>, - filename <span class='op'>=</span> <span class='st'>"CAKE_export.csf"</span>, - path <span class='op'>=</span> <span class='st'>"."</span>, - overwrite <span class='op'>=</span> <span class='cn'>FALSE</span>, - study <span class='op'>=</span> <span class='st'>"Codlemone aerobic soil degradation"</span>, - description <span class='op'>=</span> <span class='st'>""</span>, - time_unit <span class='op'>=</span> <span class='st'>"days"</span>, - res_unit <span class='op'>=</span> <span class='st'>"% AR"</span>, - comment <span class='op'>=</span> <span class='st'>"Created using mkin::CAKE_export"</span>, - date <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/Sys.time.html'>Sys.Date</a></span><span class='op'>(</span><span class='op'>)</span>, - optimiser <span class='op'>=</span> <span class='st'>"IRLS"</span> -<span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">CAKE_export</span><span class="op">(</span> + <span class="va">ds</span>, + map <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="st">"Parent"</span><span class="op">)</span>, + links <span class="op">=</span> <span class="cn">NA</span>, + filename <span class="op">=</span> <span class="st">"CAKE_export.csf"</span>, + path <span class="op">=</span> <span class="st">"."</span>, + overwrite <span class="op">=</span> <span class="cn">FALSE</span>, + study <span class="op">=</span> <span class="st">"Codlemone aerobic soil degradation"</span>, + description <span class="op">=</span> <span class="st">""</span>, + time_unit <span class="op">=</span> <span class="st">"days"</span>, + res_unit <span class="op">=</span> <span class="st">"% AR"</span>, + comment <span class="op">=</span> <span class="st">"Created using mkin::CAKE_export"</span>, + date <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/Sys.time.html" class="external-link">Sys.Date</a></span><span class="op">(</span><span class="op">)</span>, + optimiser <span class="op">=</span> <span class="st">"IRLS"</span> +<span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>ds</th> - <td><p>A named list of datasets in long format as compatible with -<code><a href='mkinfit.html'>mkinfit</a></code>.</p></td> - </tr> - <tr> - <th>map</th> - <td><p>A character vector with CAKE compartment names (Parent, A1, ...), -named with the names used in the list of datasets.</p></td> - </tr> - <tr> - <th>links</th> - <td><p>An optional character vector of target compartments, named with + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>ds</dt> +<dd><p>A named list of datasets in long format as compatible with +<code><a href="mkinfit.html">mkinfit</a></code>.</p></dd> +<dt>map</dt> +<dd><p>A character vector with CAKE compartment names (Parent, A1, ...), +named with the names used in the list of datasets.</p></dd> +<dt>links</dt> +<dd><p>An optional character vector of target compartments, named with the names of the source compartments. In order to make this easier, the -names are used as in the datasets supplied.</p></td> - </tr> - <tr> - <th>filename</th> - <td><p>Where to write the result. Should end in .csf in order to be -compatible with CAKE.</p></td> - </tr> - <tr> - <th>path</th> - <td><p>An optional path to the output file.</p></td> - </tr> - <tr> - <th>overwrite</th> - <td><p>If TRUE, existing files are overwritten.</p></td> - </tr> - <tr> - <th>study</th> - <td><p>The name of the study.</p></td> - </tr> - <tr> - <th>description</th> - <td><p>An optional description.</p></td> - </tr> - <tr> - <th>time_unit</th> - <td><p>The time unit for the residue data.</p></td> - </tr> - <tr> - <th>res_unit</th> - <td><p>The unit used for the residues.</p></td> - </tr> - <tr> - <th>comment</th> - <td><p>An optional comment.</p></td> - </tr> - <tr> - <th>date</th> - <td><p>The date of file creation.</p></td> - </tr> - <tr> - <th>optimiser</th> - <td><p>Can be OLS or IRLS.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - +names are used as in the datasets supplied.</p></dd> +<dt>filename</dt> +<dd><p>Where to write the result. Should end in .csf in order to be +compatible with CAKE.</p></dd> +<dt>path</dt> +<dd><p>An optional path to the output file.</p></dd> +<dt>overwrite</dt> +<dd><p>If TRUE, existing files are overwritten.</p></dd> +<dt>study</dt> +<dd><p>The name of the study.</p></dd> +<dt>description</dt> +<dd><p>An optional description.</p></dd> +<dt>time_unit</dt> +<dd><p>The time unit for the residue data.</p></dd> +<dt>res_unit</dt> +<dd><p>The unit used for the residues.</p></dd> +<dt>comment</dt> +<dd><p>An optional comment.</p></dd> +<dt>date</dt> +<dd><p>The date of file creation.</p></dd> +<dt>optimiser</dt> +<dd><p>Can be OLS or IRLS.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The function is called for its side effect.</p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/D24_2014.html b/docs/reference/D24_2014.html index c59bfad6..b18e6285 100644 --- a/docs/reference/D24_2014.html +++ b/docs/reference/D24_2014.html @@ -1,72 +1,17 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Aerobic soil degradation data on 2,4-D from the EU assessment in 2014 — D24_2014 • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Aerobic soil degradation data on 2,4-D from the EU assessment in 2014 — D24_2014" /> -<meta property="og:description" content="The five datasets were extracted from the active substance evaluation dossier +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Aerobic soil degradation data on 2,4-D from the EU assessment in 2014 — D24_2014 • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Aerobic soil degradation data on 2,4-D from the EU assessment in 2014 — D24_2014"><meta property="og:description" content="The five datasets were extracted from the active substance evaluation dossier published by EFSA. Kinetic evaluations shown for these datasets are intended to illustrate and advance kinetic modelling. The fact that these data and some results are shown here does not imply a license to use them in the context of pesticide registrations, as the use of the data may be -constrained by data protection regulations." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +constrained by data protection regulations."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -77,13 +22,12 @@ constrained by data protection regulations." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -92,8 +36,7 @@ constrained by data protection regulations." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -103,6 +46,9 @@ constrained by data protection regulations." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -117,34 +63,27 @@ constrained by data protection regulations." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Aerobic soil degradation data on 2,4-D from the EU assessment in 2014</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/D24_2014.R'><code>R/D24_2014.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/D24_2014.R" class="external-link"><code>R/D24_2014.R</code></a></small> <div class="hidden name"><code>D24_2014.Rd</code></div> </div> @@ -157,20 +96,23 @@ context of pesticide registrations, as the use of the data may be constrained by data protection regulations.</p> </div> - <pre class="usage"><span class='va'>D24_2014</span></pre> - - - <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2> - - <p>An <a href='mkindsg.html'>mkindsg</a> object grouping five datasets</p> - <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="va">D24_2014</span></code></pre></div> + </div> + <div id="format"> + <h2>Format</h2> + <p>An <a href="mkindsg.html">mkindsg</a> object grouping five datasets</p> + </div> + <div id="source"> + <h2>Source</h2> <p>Hellenic Ministry of Rural Development and Agriculture (2014) Final addendum to the Renewal Assessment Report - public version - 2,4-D Volume 3 Annex B.8 Fate and behaviour in the environment -<a href='http://registerofquestions.efsa.europa.eu/roqFrontend/outputLoader?output=ON-3812'>http://registerofquestions.efsa.europa.eu/roqFrontend/outputLoader?output=ON-3812</a></p> - <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2> - +<a href="http://registerofquestions.efsa.europa.eu/roqFrontend/outputLoader?output=ON-3812" class="external-link">http://registerofquestions.efsa.europa.eu/roqFrontend/outputLoader?output=ON-3812</a></p> + </div> + <div id="details"> + <h2>Details</h2> <p>Data for the first dataset are from p. 685. Data for the other four datasets were used in the preprocessed versions given in the kinetics section (p. 761ff.), with the exception of residues smaller than 1 for DCP @@ -178,114 +120,119 @@ in the soil from Site I2, where the values given on p. 694 were used.</p> <p>The R code used to create this data object is installed with this package in the 'dataset_generation' directory. In the code, page numbers are given for specific pieces of information in the comments.</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>D24_2014</span><span class='op'>)</span> -</div><div class='output co'>#> <mkindsg> holding 5 mkinds objects -#> Title $title: Aerobic soil degradation data on 2,4-D from the EU assessment in 2014 -#> Occurrence of observed compounds $observed_n: -#> D24 DCP DCA -#> 5 4 4 -#> Time normalisation factors $f_time_norm: -#> [1] 1.6062378 0.7118732 0.7156063 0.7156063 0.8977124 -#> Meta information $meta: -#> study usda_soil_type study_moisture_ref_type -#> Mississippi Cohen 1991 Silt loam <NA> -#> Fayette Liu and Adelfinskaya 2011 Silt loam pF1 -#> RefSol 03-G Liu and Adelfinskaya 2011 Loam pF1 -#> Site E1 Liu and Adelfinskaya 2011 Loam pF1 -#> Site I2 Liu and Adelfinskaya 2011 Loamy sand pF1 -#> rel_moisture temperature -#> Mississippi NA 25 -#> Fayette 0.5 20 -#> RefSol 03-G 0.5 20 -#> Site E1 0.5 20 -#> Site I2 0.5 20</div><div class='input'><span class='co'># \dontrun{</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>D24_2014</span><span class='op'>$</span><span class='va'>ds</span><span class='op'>[[</span><span class='fl'>1</span><span class='op'>]</span><span class='op'>]</span>, data <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> <mkinds> with $title: Mississippi -#> Observed compounds $observed: D24 -#> Sampling times $sampling_times: -#> 0, 2, 4, 7, 15, 24, 35, 56, 71, 114, 183, 273, 365 -#> With a maximum of 1 replicates -#> time D24 -#> 1 0 96.8 -#> 2 2 81.0 -#> 3 4 81.7 -#> 4 7 88.2 -#> 5 15 66.3 -#> 6 24 72.9 -#> 7 35 62.6 -#> 8 56 54.6 -#> 9 71 35.2 -#> 10 114 18.0 -#> 11 183 11.3 -#> 12 273 9.9 -#> 13 365 6.3</div><div class='input'><span class='va'>m_D24</span> <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>D24 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"DCP"</span><span class='op'>)</span>, - DCP <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"DCA"</span><span class='op'>)</span>, - DCA <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>m_D24</span><span class='op'>)</span> -</div><div class='output co'>#> <mkinmod> model generated with -#> Use of formation fractions $use_of_ff: max -#> Specification $spec: -#> $D24 -#> $type: SFO; $to: DCP; $sink: TRUE -#> $DCP -#> $type: SFO; $to: DCA; $sink: TRUE -#> $DCA -#> $type: SFO; $sink: TRUE -#> Coefficient matrix $coefmat available -#> Compiled model $cf available -#> Differential equations: -#> d_D24/dt = - k_D24 * D24 -#> d_DCP/dt = + f_D24_to_DCP * k_D24 * D24 - k_DCP * DCP -#> d_DCA/dt = + f_DCP_to_DCA * k_DCP * DCP - k_DCA * DCA</div><div class='input'><span class='va'>m_D24_2</span> <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>D24 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"DFOP"</span>, to <span class='op'>=</span> <span class='st'>"DCP"</span><span class='op'>)</span>, - DCP <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"DCA"</span><span class='op'>)</span>, - DCA <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>m_D24_2</span><span class='op'>)</span> -</div><div class='output co'>#> <mkinmod> model generated with -#> Use of formation fractions $use_of_ff: max -#> Specification $spec: -#> $D24 -#> $type: DFOP; $to: DCP; $sink: TRUE -#> $DCP -#> $type: SFO; $to: DCA; $sink: TRUE -#> $DCA -#> $type: SFO; $sink: TRUE -#> Compiled model $cf available -#> Differential equations: -#> d_D24/dt = - ((k1 * g * exp(-k1 * time) + k2 * (1 - g) * exp(-k2 * -#> time)) / (g * exp(-k1 * time) + (1 - g) * exp(-k2 * time))) -#> * D24 -#> d_DCP/dt = + f_D24_to_DCP * ((k1 * g * exp(-k1 * time) + k2 * (1 - g) * -#> exp(-k2 * time)) / (g * exp(-k1 * time) + (1 - g) * exp(-k2 -#> * time))) * D24 - k_DCP * DCP -#> d_DCA/dt = + f_DCP_to_DCA * k_DCP * DCP - k_DCA * DCA</div><div class='input'><span class='co'># }</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">D24_2014</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> <mkindsg> holding 5 mkinds objects</span> +<span class="r-out co"><span class="r-pr">#></span> Title $title: Aerobic soil degradation data on 2,4-D from the EU assessment in 2014 </span> +<span class="r-out co"><span class="r-pr">#></span> Occurrence of observed compounds $observed_n:</span> +<span class="r-out co"><span class="r-pr">#></span> D24 DCP DCA </span> +<span class="r-out co"><span class="r-pr">#></span> 5 4 4 </span> +<span class="r-out co"><span class="r-pr">#></span> Time normalisation factors $f_time_norm:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] 1.6062378 0.7118732 0.7156063 0.7156063 0.8977124</span> +<span class="r-out co"><span class="r-pr">#></span> Meta information $meta:</span> +<span class="r-out co"><span class="r-pr">#></span> study usda_soil_type study_moisture_ref_type</span> +<span class="r-out co"><span class="r-pr">#></span> Mississippi Cohen 1991 Silt loam <NA></span> +<span class="r-out co"><span class="r-pr">#></span> Fayette Liu and Adelfinskaya 2011 Silt loam pF1</span> +<span class="r-out co"><span class="r-pr">#></span> RefSol 03-G Liu and Adelfinskaya 2011 Loam pF1</span> +<span class="r-out co"><span class="r-pr">#></span> Site E1 Liu and Adelfinskaya 2011 Loam pF1</span> +<span class="r-out co"><span class="r-pr">#></span> Site I2 Liu and Adelfinskaya 2011 Loamy sand pF1</span> +<span class="r-out co"><span class="r-pr">#></span> rel_moisture temperature</span> +<span class="r-out co"><span class="r-pr">#></span> Mississippi NA 25</span> +<span class="r-out co"><span class="r-pr">#></span> Fayette 0.5 20</span> +<span class="r-out co"><span class="r-pr">#></span> RefSol 03-G 0.5 20</span> +<span class="r-out co"><span class="r-pr">#></span> Site E1 0.5 20</span> +<span class="r-out co"><span class="r-pr">#></span> Site I2 0.5 20</span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">D24_2014</span><span class="op">$</span><span class="va">ds</span><span class="op">[[</span><span class="fl">1</span><span class="op">]</span><span class="op">]</span>, data <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> <mkinds> with $title: Mississippi </span> +<span class="r-out co"><span class="r-pr">#></span> Observed compounds $observed: D24 </span> +<span class="r-out co"><span class="r-pr">#></span> Sampling times $sampling_times:</span> +<span class="r-out co"><span class="r-pr">#></span> 0, 2, 4, 7, 15, 24, 35, 56, 71, 114, 183, 273, 365 </span> +<span class="r-out co"><span class="r-pr">#></span> With a maximum of 1 replicates</span> +<span class="r-out co"><span class="r-pr">#></span> time D24</span> +<span class="r-out co"><span class="r-pr">#></span> 1 0 96.8</span> +<span class="r-out co"><span class="r-pr">#></span> 2 2 81.0</span> +<span class="r-out co"><span class="r-pr">#></span> 3 4 81.7</span> +<span class="r-out co"><span class="r-pr">#></span> 4 7 88.2</span> +<span class="r-out co"><span class="r-pr">#></span> 5 15 66.3</span> +<span class="r-out co"><span class="r-pr">#></span> 6 24 72.9</span> +<span class="r-out co"><span class="r-pr">#></span> 7 35 62.6</span> +<span class="r-out co"><span class="r-pr">#></span> 8 56 54.6</span> +<span class="r-out co"><span class="r-pr">#></span> 9 71 35.2</span> +<span class="r-out co"><span class="r-pr">#></span> 10 114 18.0</span> +<span class="r-out co"><span class="r-pr">#></span> 11 183 11.3</span> +<span class="r-out co"><span class="r-pr">#></span> 12 273 9.9</span> +<span class="r-out co"><span class="r-pr">#></span> 13 365 6.3</span> +<span class="r-in"><span class="va">m_D24</span> <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>D24 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"DCP"</span><span class="op">)</span>,</span> +<span class="r-in"> DCP <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"DCA"</span><span class="op">)</span>,</span> +<span class="r-in"> DCA <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">m_D24</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> <mkinmod> model generated with</span> +<span class="r-out co"><span class="r-pr">#></span> Use of formation fractions $use_of_ff: max </span> +<span class="r-out co"><span class="r-pr">#></span> Specification $spec:</span> +<span class="r-out co"><span class="r-pr">#></span> $D24</span> +<span class="r-out co"><span class="r-pr">#></span> $type: SFO; $to: DCP; $sink: TRUE</span> +<span class="r-out co"><span class="r-pr">#></span> $DCP</span> +<span class="r-out co"><span class="r-pr">#></span> $type: SFO; $to: DCA; $sink: TRUE</span> +<span class="r-out co"><span class="r-pr">#></span> $DCA</span> +<span class="r-out co"><span class="r-pr">#></span> $type: SFO; $sink: TRUE</span> +<span class="r-out co"><span class="r-pr">#></span> Coefficient matrix $coefmat available</span> +<span class="r-out co"><span class="r-pr">#></span> Compiled model $cf available</span> +<span class="r-out co"><span class="r-pr">#></span> Differential equations:</span> +<span class="r-out co"><span class="r-pr">#></span> d_D24/dt = - k_D24 * D24</span> +<span class="r-out co"><span class="r-pr">#></span> d_DCP/dt = + f_D24_to_DCP * k_D24 * D24 - k_DCP * DCP</span> +<span class="r-out co"><span class="r-pr">#></span> d_DCA/dt = + f_DCP_to_DCA * k_DCP * DCP - k_DCA * DCA</span> +<span class="r-in"><span class="va">m_D24_2</span> <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>D24 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"DFOP"</span>, to <span class="op">=</span> <span class="st">"DCP"</span><span class="op">)</span>,</span> +<span class="r-in"> DCP <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"DCA"</span><span class="op">)</span>,</span> +<span class="r-in"> DCA <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">m_D24_2</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> <mkinmod> model generated with</span> +<span class="r-out co"><span class="r-pr">#></span> Use of formation fractions $use_of_ff: max </span> +<span class="r-out co"><span class="r-pr">#></span> Specification $spec:</span> +<span class="r-out co"><span class="r-pr">#></span> $D24</span> +<span class="r-out co"><span class="r-pr">#></span> $type: DFOP; $to: DCP; $sink: TRUE</span> +<span class="r-out co"><span class="r-pr">#></span> $DCP</span> +<span class="r-out co"><span class="r-pr">#></span> $type: SFO; $to: DCA; $sink: TRUE</span> +<span class="r-out co"><span class="r-pr">#></span> $DCA</span> +<span class="r-out co"><span class="r-pr">#></span> $type: SFO; $sink: TRUE</span> +<span class="r-out co"><span class="r-pr">#></span> Compiled model $cf available</span> +<span class="r-out co"><span class="r-pr">#></span> Differential equations:</span> +<span class="r-out co"><span class="r-pr">#></span> d_D24/dt = - ((k1 * g * exp(-k1 * time) + k2 * (1 - g) * exp(-k2 *</span> +<span class="r-out co"><span class="r-pr">#></span> time)) / (g * exp(-k1 * time) + (1 - g) * exp(-k2 * time)))</span> +<span class="r-out co"><span class="r-pr">#></span> * D24</span> +<span class="r-out co"><span class="r-pr">#></span> d_DCP/dt = + f_D24_to_DCP * ((k1 * g * exp(-k1 * time) + k2 * (1 - g) *</span> +<span class="r-out co"><span class="r-pr">#></span> exp(-k2 * time)) / (g * exp(-k1 * time) + (1 - g) * exp(-k2</span> +<span class="r-out co"><span class="r-pr">#></span> * time))) * D24 - k_DCP * DCP</span> +<span class="r-out co"><span class="r-pr">#></span> d_DCA/dt = + f_DCP_to_DCA * k_DCP * DCP - k_DCA * DCA</span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/DFOP.solution-1.png b/docs/reference/DFOP.solution-1.png Binary files differindex 616e19d5..5ebba336 100644 --- a/docs/reference/DFOP.solution-1.png +++ b/docs/reference/DFOP.solution-1.png diff --git a/docs/reference/DFOP.solution.html b/docs/reference/DFOP.solution.html index d04f98cc..335590f7 100644 --- a/docs/reference/DFOP.solution.html +++ b/docs/reference/DFOP.solution.html @@ -1,68 +1,13 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Double First-Order in Parallel kinetics — DFOP.solution • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Double First-Order in Parallel kinetics — DFOP.solution" /> -<meta property="og:description" content="Function describing decline from a defined starting value using the sum of -two exponential decline functions." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Double First-Order in Parallel kinetics — DFOP.solution • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Double First-Order in Parallel kinetics — DFOP.solution"><meta property="og:description" content="Function describing decline from a defined starting value using the sum of +two exponential decline functions."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -73,13 +18,12 @@ two exponential decline functions." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -88,8 +32,7 @@ two exponential decline functions." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -99,6 +42,9 @@ two exponential decline functions." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -113,34 +59,27 @@ two exponential decline functions." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Double First-Order in Parallel kinetics</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/parent_solutions.R'><code>R/parent_solutions.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/parent_solutions.R" class="external-link"><code>R/parent_solutions.R</code></a></small> <div class="hidden name"><code>DFOP.solution.Rd</code></div> </div> @@ -149,89 +88,81 @@ two exponential decline functions." /> two exponential decline functions.</p> </div> - <pre class="usage"><span class='fu'>DFOP.solution</span><span class='op'>(</span><span class='va'>t</span>, <span class='va'>parent_0</span>, <span class='va'>k1</span>, <span class='va'>k2</span>, <span class='va'>g</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>t</th> - <td><p>Time.</p></td> - </tr> - <tr> - <th>parent_0</th> - <td><p>Starting value for the response variable at time zero.</p></td> - </tr> - <tr> - <th>k1</th> - <td><p>First kinetic constant.</p></td> - </tr> - <tr> - <th>k2</th> - <td><p>Second kinetic constant.</p></td> - </tr> - <tr> - <th>g</th> - <td><p>Fraction of the starting value declining according to the first -kinetic constant.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">DFOP.solution</span><span class="op">(</span><span class="va">t</span>, <span class="va">parent_0</span>, <span class="va">k1</span>, <span class="va">k2</span>, <span class="va">g</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>t</dt> +<dd><p>Time.</p></dd> +<dt>parent_0</dt> +<dd><p>Starting value for the response variable at time zero.</p></dd> +<dt>k1</dt> +<dd><p>First kinetic constant.</p></dd> +<dt>k2</dt> +<dd><p>Second kinetic constant.</p></dd> +<dt>g</dt> +<dd><p>Fraction of the starting value declining according to the first +kinetic constant.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The value of the response variable at time <code>t</code>.</p> - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - - <p>FOCUS (2006) “Guidance Document on Estimating Persistence + </div> + <div id="references"> + <h2>References</h2> + <p>FOCUS (2006) “Guidance Document on Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC Document Reference Sanco/10058/2005 version 2.0, 434 pp, -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a> -FOCUS (2014) “Generic guidance for Estimating Persistence +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a> +FOCUS (2014) “Generic guidance for Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, Version 1.1, 18 December 2014 -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p>Other parent solutions: -<code><a href='FOMC.solution.html'>FOMC.solution</a>()</code>, -<code><a href='HS.solution.html'>HS.solution</a>()</code>, -<code><a href='IORE.solution.html'>IORE.solution</a>()</code>, -<code><a href='SFO.solution.html'>SFO.solution</a>()</code>, -<code><a href='SFORB.solution.html'>SFORB.solution</a>()</code>, -<code><a href='logistic.solution.html'>logistic.solution</a>()</code></p></div> - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> - <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='fu'>DFOP.solution</span><span class='op'>(</span><span class='va'>x</span>, <span class='fl'>100</span>, <span class='fl'>5</span>, <span class='fl'>0.5</span>, <span class='fl'>0.3</span><span class='op'>)</span>, <span class='fl'>0</span>, <span class='fl'>4</span>, ylim <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0</span>,<span class='fl'>100</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='img'><img src='DFOP.solution-1.png' alt='' width='700' height='433' /></div><div class='input'> -</div></pre> +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p>Other parent solutions: +<code><a href="FOMC.solution.html">FOMC.solution</a>()</code>, +<code><a href="HS.solution.html">HS.solution</a>()</code>, +<code><a href="IORE.solution.html">IORE.solution</a>()</code>, +<code><a href="SFO.solution.html">SFO.solution</a>()</code>, +<code><a href="SFORB.solution.html">SFORB.solution</a>()</code>, +<code><a href="logistic.solution.html">logistic.solution</a>()</code></p></div> + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu">DFOP.solution</span><span class="op">(</span><span class="va">x</span>, <span class="fl">100</span>, <span class="fl">5</span>, <span class="fl">0.5</span>, <span class="fl">0.3</span><span class="op">)</span>, <span class="fl">0</span>, <span class="fl">4</span>, ylim <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0</span>,<span class="fl">100</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-plt img"><img src="DFOP.solution-1.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/Extract.mmkin.html b/docs/reference/Extract.mmkin.html index b1c73ba5..49578dc7 100644 --- a/docs/reference/Extract.mmkin.html +++ b/docs/reference/Extract.mmkin.html @@ -1,67 +1,12 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Subsetting method for mmkin objects — [.mmkin • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Subsetting method for mmkin objects — [.mmkin" /> -<meta property="og:description" content="Subsetting method for mmkin objects" /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Subsetting method for mmkin objects — [.mmkin • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Subsetting method for mmkin objects — [.mmkin"><meta property="og:description" content="Subsetting method for mmkin objects"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -72,13 +17,12 @@ </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -87,8 +31,7 @@ <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -98,6 +41,9 @@ <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -112,34 +58,27 @@ <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Subsetting method for mmkin objects</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/mmkin.R'><code>R/mmkin.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/mmkin.R" class="external-link"><code>R/mmkin.R</code></a></small> <div class="hidden name"><code>Extract.mmkin.Rd</code></div> </div> @@ -147,122 +86,116 @@ <p>Subsetting method for mmkin objects</p> </div> - <pre class="usage"># S3 method for mmkin -[(x, i, j, ..., drop = FALSE)</pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>x</th> - <td><p>An <code><a href='mmkin.html'>mmkin</a> object</code></p></td> - </tr> - <tr> - <th>i</th> - <td><p>Row index selecting the fits for specific models</p></td> - </tr> - <tr> - <th>j</th> - <td><p>Column index selecting the fits to specific datasets</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Not used, only there to satisfy the generic method definition</p></td> - </tr> - <tr> - <th>drop</th> - <td><p>If FALSE, the method always returns an mmkin object, otherwise -either a list of mkinfit objects or a single mkinfit object.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - - <p>An object of class <code><a href='mmkin.html'>mmkin</a></code>.</p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre><code># S3 method for mmkin +[(x, i, j, ..., drop = FALSE)</code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>x</dt> +<dd><p>An <code><a href="mmkin.html">mmkin</a> object</code></p></dd> +<dt>i</dt> +<dd><p>Row index selecting the fits for specific models</p></dd> +<dt>j</dt> +<dd><p>Column index selecting the fits to specific datasets</p></dd> +<dt>...</dt> +<dd><p>Not used, only there to satisfy the generic method definition</p></dd> +<dt>drop</dt> +<dd><p>If FALSE, the method always returns an mmkin object, otherwise +either a list of mkinfit objects or a single mkinfit object.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>An object of class <code><a href="mmkin.html">mmkin</a></code>.</p> + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> - <span class='co'># Only use one core, to pass R CMD check --as-cran</span> - <span class='va'>fits</span> <span class='op'><-</span> <span class='fu'><a href='mmkin.html'>mmkin</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"FOMC"</span><span class='op'>)</span>, <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>B <span class='op'>=</span> <span class='va'>FOCUS_2006_B</span>, C <span class='op'>=</span> <span class='va'>FOCUS_2006_C</span><span class='op'>)</span>, - cores <span class='op'>=</span> <span class='fl'>1</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - <span class='va'>fits</span><span class='op'>[</span><span class='st'>"FOMC"</span>, <span class='op'>]</span> -</div><div class='output co'>#> <mmkin> object -#> Status of individual fits: -#> -#> dataset -#> model B C -#> FOMC OK OK -#> -#> OK: No warnings</div><div class='input'> <span class='va'>fits</span><span class='op'>[</span>, <span class='st'>"B"</span><span class='op'>]</span> -</div><div class='output co'>#> <mmkin> object -#> Status of individual fits: -#> -#> dataset -#> model B -#> SFO OK -#> FOMC OK -#> -#> OK: No warnings</div><div class='input'> <span class='va'>fits</span><span class='op'>[</span><span class='st'>"SFO"</span>, <span class='st'>"B"</span><span class='op'>]</span> -</div><div class='output co'>#> <mmkin> object -#> Status of individual fits: -#> -#> dataset -#> model B -#> SFO OK -#> -#> OK: No warnings</div><div class='input'> - <span class='fu'><a href='https://rdrr.io/r/utils/head.html'>head</a></span><span class='op'>(</span> - <span class='co'># This extracts an mkinfit object with lots of components</span> - <span class='va'>fits</span><span class='op'>[[</span><span class='st'>"FOMC"</span>, <span class='st'>"B"</span><span class='op'>]</span><span class='op'>]</span> - <span class='op'>)</span> -</div><div class='output co'>#> $par -#> parent_0 log_alpha log_beta sigma -#> 99.666192 2.549850 5.050586 1.890202 -#> -#> $objective -#> [1] 28.58291 -#> -#> $convergence -#> [1] 0 -#> -#> $iterations -#> [1] 21 -#> -#> $evaluations -#> function gradient -#> 25 78 -#> -#> $message -#> [1] "both X-convergence and relative convergence (5)" -#> </div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"> <span class="co"># Only use one core, to pass R CMD check --as-cran</span></span> +<span class="r-in"> <span class="va">fits</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"FOMC"</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>B <span class="op">=</span> <span class="va">FOCUS_2006_B</span>, C <span class="op">=</span> <span class="va">FOCUS_2006_C</span><span class="op">)</span>,</span> +<span class="r-in"> cores <span class="op">=</span> <span class="fl">1</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">fits</span><span class="op">[</span><span class="st">"FOMC"</span>, <span class="op">]</span></span> +<span class="r-out co"><span class="r-pr">#></span> <mmkin> object</span> +<span class="r-out co"><span class="r-pr">#></span> Status of individual fits:</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> dataset</span> +<span class="r-out co"><span class="r-pr">#></span> model B C </span> +<span class="r-out co"><span class="r-pr">#></span> FOMC OK OK</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> OK: No warnings</span> +<span class="r-in"> <span class="va">fits</span><span class="op">[</span>, <span class="st">"B"</span><span class="op">]</span></span> +<span class="r-out co"><span class="r-pr">#></span> <mmkin> object</span> +<span class="r-out co"><span class="r-pr">#></span> Status of individual fits:</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> dataset</span> +<span class="r-out co"><span class="r-pr">#></span> model B </span> +<span class="r-out co"><span class="r-pr">#></span> SFO OK</span> +<span class="r-out co"><span class="r-pr">#></span> FOMC OK</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> OK: No warnings</span> +<span class="r-in"> <span class="va">fits</span><span class="op">[</span><span class="st">"SFO"</span>, <span class="st">"B"</span><span class="op">]</span></span> +<span class="r-out co"><span class="r-pr">#></span> <mmkin> object</span> +<span class="r-out co"><span class="r-pr">#></span> Status of individual fits:</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> dataset</span> +<span class="r-out co"><span class="r-pr">#></span> model B </span> +<span class="r-out co"><span class="r-pr">#></span> SFO OK</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> OK: No warnings</span> +<span class="r-in"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/utils/head.html" class="external-link">head</a></span><span class="op">(</span></span> +<span class="r-in"> <span class="co"># This extracts an mkinfit object with lots of components</span></span> +<span class="r-in"> <span class="va">fits</span><span class="op">[[</span><span class="st">"FOMC"</span>, <span class="st">"B"</span><span class="op">]</span><span class="op">]</span></span> +<span class="r-in"> <span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> $par</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_alpha log_beta sigma </span> +<span class="r-out co"><span class="r-pr">#></span> 99.666192 2.549850 5.050586 1.890202 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $objective</span> +<span class="r-out co"><span class="r-pr">#></span> [1] 28.58291</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $convergence</span> +<span class="r-out co"><span class="r-pr">#></span> [1] 0</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $iterations</span> +<span class="r-out co"><span class="r-pr">#></span> [1] 21</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $evaluations</span> +<span class="r-out co"><span class="r-pr">#></span> function gradient </span> +<span class="r-out co"><span class="r-pr">#></span> 25 78 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $message</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "both X-convergence and relative convergence (5)"</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/FOCUS_2006_DFOP_ref_A_to_B.html b/docs/reference/FOCUS_2006_DFOP_ref_A_to_B.html index ba1cb19a..c8bfb9dd 100644 --- a/docs/reference/FOCUS_2006_DFOP_ref_A_to_B.html +++ b/docs/reference/FOCUS_2006_DFOP_ref_A_to_B.html @@ -1,71 +1,16 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Results of fitting the DFOP model to Datasets A to B of FOCUS (2006) — FOCUS_2006_DFOP_ref_A_to_B • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Results of fitting the DFOP model to Datasets A to B of FOCUS (2006) — FOCUS_2006_DFOP_ref_A_to_B" /> -<meta property="og:description" content="A table with the fitted parameters and the resulting DT50 and DT90 values +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Results of fitting the DFOP model to Datasets A to B of FOCUS (2006) — FOCUS_2006_DFOP_ref_A_to_B • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Results of fitting the DFOP model to Datasets A to B of FOCUS (2006) — FOCUS_2006_DFOP_ref_A_to_B"><meta property="og:description" content="A table with the fitted parameters and the resulting DT50 and DT90 values generated with different software packages. Taken directly from FOCUS (2006). The results from fitting the data with the Topfit software was removed, as the initial concentration of the parent compound was fixed to a value of 100 -in this fit." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +in this fit."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -76,13 +21,12 @@ in this fit." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -91,8 +35,7 @@ in this fit." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -102,6 +45,9 @@ in this fit." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -116,30 +62,23 @@ in this fit." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Results of fitting the DFOP model to Datasets A to B of FOCUS (2006)</h1> @@ -155,59 +94,73 @@ the initial concentration of the parent compound was fixed to a value of 100 in this fit.</p> </div> - <pre class="usage"><span class='va'>FOCUS_2006_DFOP_ref_A_to_B</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="va">FOCUS_2006_DFOP_ref_A_to_B</span></code></pre></div> + </div> + + <div id="format"> + <h2>Format</h2> + <p>A data frame containing the following variables.</p><dl><dt><code>package</code></dt> +<dd><p>a factor giving the name of the software package</p></dd> + <dt><code>M0</code></dt> +<dd><p>The fitted initial concentration of the parent compound</p></dd> - <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2> + <dt><code>f</code></dt> +<dd><p>The fitted f parameter</p></dd> - <p>A data frame containing the following variables.</p><dl> - <dt><code>package</code></dt><dd><p>a factor giving the name of the software package</p></dd> - <dt><code>M0</code></dt><dd><p>The fitted initial concentration of the parent compound</p></dd> - <dt><code>f</code></dt><dd><p>The fitted f parameter</p></dd> - <dt><code>k1</code></dt><dd><p>The fitted k1 parameter</p></dd> - <dt><code>k2</code></dt><dd><p>The fitted k2 parameter</p></dd> - <dt><code>DT50</code></dt><dd><p>The resulting half-life of the parent compound</p></dd> - <dt><code>DT90</code></dt><dd><p>The resulting DT90 of the parent compound</p></dd> - <dt><code>dataset</code></dt><dd><p>The FOCUS dataset that was used</p></dd> - -</dl> + <dt><code>k1</code></dt> +<dd><p>The fitted k1 parameter</p></dd> + + <dt><code>k2</code></dt> +<dd><p>The fitted k2 parameter</p></dd> + + <dt><code>DT50</code></dt> +<dd><p>The resulting half-life of the parent compound</p></dd> + + <dt><code>DT90</code></dt> +<dd><p>The resulting DT90 of the parent compound</p></dd> - <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2> + <dt><code>dataset</code></dt> +<dd><p>The FOCUS dataset that was used</p></dd> - <p>FOCUS (2006) “Guidance Document on Estimating Persistence and + +</dl></div> + <div id="source"> + <h2>Source</h2> + <p>FOCUS (2006) “Guidance Document on Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in EU - Registration” Report of the FOCUS Work Group on Degradation Kinetics, + Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC Document Reference Sanco/10058/2005 version 2.0, 434 pp, - <a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + <a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='fu'><a href='https://rdrr.io/r/utils/data.html'>data</a></span><span class='op'>(</span><span class='va'>FOCUS_2006_DFOP_ref_A_to_B</span><span class='op'>)</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="fu"><a href="https://rdrr.io/r/utils/data.html" class="external-link">data</a></span><span class="op">(</span><span class="va">FOCUS_2006_DFOP_ref_A_to_B</span><span class="op">)</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/FOCUS_2006_FOMC_ref_A_to_F.html b/docs/reference/FOCUS_2006_FOMC_ref_A_to_F.html index cfb60536..c332446f 100644 --- a/docs/reference/FOCUS_2006_FOMC_ref_A_to_F.html +++ b/docs/reference/FOCUS_2006_FOMC_ref_A_to_F.html @@ -1,71 +1,16 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Results of fitting the FOMC model to Datasets A to F of FOCUS (2006) — FOCUS_2006_FOMC_ref_A_to_F • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Results of fitting the FOMC model to Datasets A to F of FOCUS (2006) — FOCUS_2006_FOMC_ref_A_to_F" /> -<meta property="og:description" content="A table with the fitted parameters and the resulting DT50 and DT90 values +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Results of fitting the FOMC model to Datasets A to F of FOCUS (2006) — FOCUS_2006_FOMC_ref_A_to_F • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Results of fitting the FOMC model to Datasets A to F of FOCUS (2006) — FOCUS_2006_FOMC_ref_A_to_F"><meta property="og:description" content="A table with the fitted parameters and the resulting DT50 and DT90 values generated with different software packages. Taken directly from FOCUS (2006). The results from fitting the data with the Topfit software was removed, as the initial concentration of the parent compound was fixed to a value of 100 -in this fit." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +in this fit."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -76,13 +21,12 @@ in this fit." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -91,8 +35,7 @@ in this fit." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -102,6 +45,9 @@ in this fit." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -116,30 +62,23 @@ in this fit." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Results of fitting the FOMC model to Datasets A to F of FOCUS (2006)</h1> @@ -155,58 +94,70 @@ the initial concentration of the parent compound was fixed to a value of 100 in this fit.</p> </div> - <pre class="usage"><span class='va'>FOCUS_2006_FOMC_ref_A_to_F</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="va">FOCUS_2006_FOMC_ref_A_to_F</span></code></pre></div> + </div> + <div id="format"> + <h2>Format</h2> + <p>A data frame containing the following variables.</p><dl><dt><code>package</code></dt> +<dd><p>a factor giving the name of the software package</p></dd> - <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2> + <dt><code>M0</code></dt> +<dd><p>The fitted initial concentration of the parent compound</p></dd> - <p>A data frame containing the following variables.</p><dl> - <dt><code>package</code></dt><dd><p>a factor giving the name of the software package</p></dd> - <dt><code>M0</code></dt><dd><p>The fitted initial concentration of the parent compound</p></dd> - <dt><code>alpha</code></dt><dd><p>The fitted alpha parameter</p></dd> - <dt><code>beta</code></dt><dd><p>The fitted beta parameter</p></dd> - <dt><code>DT50</code></dt><dd><p>The resulting half-life of the parent compound</p></dd> - <dt><code>DT90</code></dt><dd><p>The resulting DT90 of the parent compound</p></dd> - <dt><code>dataset</code></dt><dd><p>The FOCUS dataset that was used</p></dd> - -</dl> + <dt><code>alpha</code></dt> +<dd><p>The fitted alpha parameter</p></dd> + + <dt><code>beta</code></dt> +<dd><p>The fitted beta parameter</p></dd> + + <dt><code>DT50</code></dt> +<dd><p>The resulting half-life of the parent compound</p></dd> - <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2> + <dt><code>DT90</code></dt> +<dd><p>The resulting DT90 of the parent compound</p></dd> - <p>FOCUS (2006) “Guidance Document on Estimating Persistence and + <dt><code>dataset</code></dt> +<dd><p>The FOCUS dataset that was used</p></dd> + + +</dl></div> + <div id="source"> + <h2>Source</h2> + <p>FOCUS (2006) “Guidance Document on Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in EU - Registration” Report of the FOCUS Work Group on Degradation Kinetics, + Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC Document Reference Sanco/10058/2005 version 2.0, 434 pp, - <a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + <a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='fu'><a href='https://rdrr.io/r/utils/data.html'>data</a></span><span class='op'>(</span><span class='va'>FOCUS_2006_FOMC_ref_A_to_F</span><span class='op'>)</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="fu"><a href="https://rdrr.io/r/utils/data.html" class="external-link">data</a></span><span class="op">(</span><span class="va">FOCUS_2006_FOMC_ref_A_to_F</span><span class="op">)</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/FOCUS_2006_HS_ref_A_to_F.html b/docs/reference/FOCUS_2006_HS_ref_A_to_F.html index c90bcdbb..151925d9 100644 --- a/docs/reference/FOCUS_2006_HS_ref_A_to_F.html +++ b/docs/reference/FOCUS_2006_HS_ref_A_to_F.html @@ -1,71 +1,16 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Results of fitting the HS model to Datasets A to F of FOCUS (2006) — FOCUS_2006_HS_ref_A_to_F • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Results of fitting the HS model to Datasets A to F of FOCUS (2006) — FOCUS_2006_HS_ref_A_to_F" /> -<meta property="og:description" content="A table with the fitted parameters and the resulting DT50 and DT90 values +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Results of fitting the HS model to Datasets A to F of FOCUS (2006) — FOCUS_2006_HS_ref_A_to_F • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Results of fitting the HS model to Datasets A to F of FOCUS (2006) — FOCUS_2006_HS_ref_A_to_F"><meta property="og:description" content="A table with the fitted parameters and the resulting DT50 and DT90 values generated with different software packages. Taken directly from FOCUS (2006). The results from fitting the data with the Topfit software was removed, as the initial concentration of the parent compound was fixed to a value of 100 -in this fit." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +in this fit."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -76,13 +21,12 @@ in this fit." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -91,8 +35,7 @@ in this fit." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -102,6 +45,9 @@ in this fit." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -116,30 +62,23 @@ in this fit." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Results of fitting the HS model to Datasets A to F of FOCUS (2006)</h1> @@ -155,59 +94,73 @@ the initial concentration of the parent compound was fixed to a value of 100 in this fit.</p> </div> - <pre class="usage"><span class='va'>FOCUS_2006_HS_ref_A_to_F</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="va">FOCUS_2006_HS_ref_A_to_F</span></code></pre></div> + </div> + + <div id="format"> + <h2>Format</h2> + <p>A data frame containing the following variables.</p><dl><dt><code>package</code></dt> +<dd><p>a factor giving the name of the software package</p></dd> + <dt><code>M0</code></dt> +<dd><p>The fitted initial concentration of the parent compound</p></dd> - <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2> + <dt><code>tb</code></dt> +<dd><p>The fitted tb parameter</p></dd> - <p>A data frame containing the following variables.</p><dl> - <dt><code>package</code></dt><dd><p>a factor giving the name of the software package</p></dd> - <dt><code>M0</code></dt><dd><p>The fitted initial concentration of the parent compound</p></dd> - <dt><code>tb</code></dt><dd><p>The fitted tb parameter</p></dd> - <dt><code>k1</code></dt><dd><p>The fitted k1 parameter</p></dd> - <dt><code>k2</code></dt><dd><p>The fitted k2 parameter</p></dd> - <dt><code>DT50</code></dt><dd><p>The resulting half-life of the parent compound</p></dd> - <dt><code>DT90</code></dt><dd><p>The resulting DT90 of the parent compound</p></dd> - <dt><code>dataset</code></dt><dd><p>The FOCUS dataset that was used</p></dd> - -</dl> + <dt><code>k1</code></dt> +<dd><p>The fitted k1 parameter</p></dd> + + <dt><code>k2</code></dt> +<dd><p>The fitted k2 parameter</p></dd> + + <dt><code>DT50</code></dt> +<dd><p>The resulting half-life of the parent compound</p></dd> + + <dt><code>DT90</code></dt> +<dd><p>The resulting DT90 of the parent compound</p></dd> - <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2> + <dt><code>dataset</code></dt> +<dd><p>The FOCUS dataset that was used</p></dd> - <p>FOCUS (2006) “Guidance Document on Estimating Persistence and + +</dl></div> + <div id="source"> + <h2>Source</h2> + <p>FOCUS (2006) “Guidance Document on Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in EU - Registration” Report of the FOCUS Work Group on Degradation Kinetics, + Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC Document Reference Sanco/10058/2005 version 2.0, 434 pp, - <a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + <a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='fu'><a href='https://rdrr.io/r/utils/data.html'>data</a></span><span class='op'>(</span><span class='va'>FOCUS_2006_HS_ref_A_to_F</span><span class='op'>)</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="fu"><a href="https://rdrr.io/r/utils/data.html" class="external-link">data</a></span><span class="op">(</span><span class="va">FOCUS_2006_HS_ref_A_to_F</span><span class="op">)</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/FOCUS_2006_SFO_ref_A_to_F.html b/docs/reference/FOCUS_2006_SFO_ref_A_to_F.html index 7b2747dc..f8e368cf 100644 --- a/docs/reference/FOCUS_2006_SFO_ref_A_to_F.html +++ b/docs/reference/FOCUS_2006_SFO_ref_A_to_F.html @@ -1,71 +1,16 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Results of fitting the SFO model to Datasets A to F of FOCUS (2006) — FOCUS_2006_SFO_ref_A_to_F • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Results of fitting the SFO model to Datasets A to F of FOCUS (2006) — FOCUS_2006_SFO_ref_A_to_F" /> -<meta property="og:description" content="A table with the fitted parameters and the resulting DT50 and DT90 values +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Results of fitting the SFO model to Datasets A to F of FOCUS (2006) — FOCUS_2006_SFO_ref_A_to_F • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Results of fitting the SFO model to Datasets A to F of FOCUS (2006) — FOCUS_2006_SFO_ref_A_to_F"><meta property="og:description" content="A table with the fitted parameters and the resulting DT50 and DT90 values generated with different software packages. Taken directly from FOCUS (2006). The results from fitting the data with the Topfit software was removed, as the initial concentration of the parent compound was fixed to a value of 100 -in this fit." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +in this fit."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -76,13 +21,12 @@ in this fit." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -91,8 +35,7 @@ in this fit." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -102,6 +45,9 @@ in this fit." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -116,30 +62,23 @@ in this fit." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Results of fitting the SFO model to Datasets A to F of FOCUS (2006)</h1> @@ -155,57 +94,67 @@ the initial concentration of the parent compound was fixed to a value of 100 in this fit.</p> </div> - <pre class="usage"><span class='va'>FOCUS_2006_SFO_ref_A_to_F</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="va">FOCUS_2006_SFO_ref_A_to_F</span></code></pre></div> + </div> + <div id="format"> + <h2>Format</h2> + <p>A data frame containing the following variables.</p><dl><dt><code>package</code></dt> +<dd><p>a factor giving the name of the software package</p></dd> - <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2> + <dt><code>M0</code></dt> +<dd><p>The fitted initial concentration of the parent compound</p></dd> - <p>A data frame containing the following variables.</p><dl> - <dt><code>package</code></dt><dd><p>a factor giving the name of the software package</p></dd> - <dt><code>M0</code></dt><dd><p>The fitted initial concentration of the parent compound</p></dd> - <dt><code>k</code></dt><dd><p>The fitted first-order degradation rate constant</p></dd> - <dt><code>DT50</code></dt><dd><p>The resulting half-life of the parent compound</p></dd> - <dt><code>DT90</code></dt><dd><p>The resulting DT90 of the parent compound</p></dd> - <dt><code>dataset</code></dt><dd><p>The FOCUS dataset that was used</p></dd> - -</dl> + <dt><code>k</code></dt> +<dd><p>The fitted first-order degradation rate constant</p></dd> + + <dt><code>DT50</code></dt> +<dd><p>The resulting half-life of the parent compound</p></dd> - <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2> + <dt><code>DT90</code></dt> +<dd><p>The resulting DT90 of the parent compound</p></dd> - <p>FOCUS (2006) “Guidance Document on Estimating Persistence and + <dt><code>dataset</code></dt> +<dd><p>The FOCUS dataset that was used</p></dd> + + +</dl></div> + <div id="source"> + <h2>Source</h2> + <p>FOCUS (2006) “Guidance Document on Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in EU - Registration” Report of the FOCUS Work Group on Degradation Kinetics, + Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC Document Reference Sanco/10058/2005 version 2.0, 434 pp, - <a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + <a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='fu'><a href='https://rdrr.io/r/utils/data.html'>data</a></span><span class='op'>(</span><span class='va'>FOCUS_2006_SFO_ref_A_to_F</span><span class='op'>)</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="fu"><a href="https://rdrr.io/r/utils/data.html" class="external-link">data</a></span><span class="op">(</span><span class="va">FOCUS_2006_SFO_ref_A_to_F</span><span class="op">)</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/FOCUS_2006_datasets.html b/docs/reference/FOCUS_2006_datasets.html index 7a39dcd0..a1004d39 100644 --- a/docs/reference/FOCUS_2006_datasets.html +++ b/docs/reference/FOCUS_2006_datasets.html @@ -1,67 +1,12 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Datasets A to F from the FOCUS Kinetics report from 2006 — FOCUS_2006_datasets • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Datasets A to F from the FOCUS Kinetics report from 2006 — FOCUS_2006_datasets" /> -<meta property="og:description" content="Data taken from FOCUS (2006), p. 258." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Datasets A to F from the FOCUS Kinetics report from 2006 — FOCUS_2006_datasets • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Datasets A to F from the FOCUS Kinetics report from 2006 — FOCUS_2006_datasets"><meta property="og:description" content="Data taken from FOCUS (2006), p. 258."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -72,13 +17,12 @@ </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -87,8 +31,7 @@ <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -98,6 +41,9 @@ <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -112,30 +58,23 @@ <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Datasets A to F from the FOCUS Kinetics report from 2006</h1> @@ -147,68 +86,73 @@ <p>Data taken from FOCUS (2006), p. 258.</p> </div> - <pre class="usage"><span class='va'>FOCUS_2006_A</span> - <span class='va'>FOCUS_2006_B</span> - <span class='va'>FOCUS_2006_C</span> - <span class='va'>FOCUS_2006_D</span> - <span class='va'>FOCUS_2006_E</span> - <span class='va'>FOCUS_2006_F</span></pre> - + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="va">FOCUS_2006_A</span> + <span class="va">FOCUS_2006_B</span> + <span class="va">FOCUS_2006_C</span> + <span class="va">FOCUS_2006_D</span> + <span class="va">FOCUS_2006_E</span> + <span class="va">FOCUS_2006_F</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2> + <div id="format"> + <h2>Format</h2> + <p>6 datasets with observations on the following variables.</p><dl><dt><code>name</code></dt> +<dd><p>a factor containing the name of the observed variable</p></dd> - <p>6 datasets with observations on the following variables.</p><dl> - <dt><code>name</code></dt><dd><p>a factor containing the name of the observed variable</p></dd> - <dt><code>time</code></dt><dd><p>a numeric vector containing time points</p></dd> - <dt><code>value</code></dt><dd><p>a numeric vector containing concentrations in percent of applied radioactivity</p></dd> - -</dl> + <dt><code>time</code></dt> +<dd><p>a numeric vector containing time points</p></dd> - <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2> + <dt><code>value</code></dt> +<dd><p>a numeric vector containing concentrations in percent of applied radioactivity</p></dd> - <p>FOCUS (2006) “Guidance Document on Estimating Persistence and + +</dl></div> + <div id="source"> + <h2>Source</h2> + <p>FOCUS (2006) “Guidance Document on Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in EU - Registration” Report of the FOCUS Work Group on Degradation Kinetics, + Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC Document Reference Sanco/10058/2005 version 2.0, 434 pp, - <a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='va'>FOCUS_2006_C</span> -</div><div class='output co'>#> name time value -#> 1 parent 0 85.1 -#> 2 parent 1 57.9 -#> 3 parent 3 29.9 -#> 4 parent 7 14.6 -#> 5 parent 14 9.7 -#> 6 parent 28 6.6 -#> 7 parent 63 4.0 -#> 8 parent 91 3.9 -#> 9 parent 119 0.6</div></pre> + <a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="va">FOCUS_2006_C</span></span> +<span class="r-out co"><span class="r-pr">#></span> name time value</span> +<span class="r-out co"><span class="r-pr">#></span> 1 parent 0 85.1</span> +<span class="r-out co"><span class="r-pr">#></span> 2 parent 1 57.9</span> +<span class="r-out co"><span class="r-pr">#></span> 3 parent 3 29.9</span> +<span class="r-out co"><span class="r-pr">#></span> 4 parent 7 14.6</span> +<span class="r-out co"><span class="r-pr">#></span> 5 parent 14 9.7</span> +<span class="r-out co"><span class="r-pr">#></span> 6 parent 28 6.6</span> +<span class="r-out co"><span class="r-pr">#></span> 7 parent 63 4.0</span> +<span class="r-out co"><span class="r-pr">#></span> 8 parent 91 3.9</span> +<span class="r-out co"><span class="r-pr">#></span> 9 parent 119 0.6</span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/FOMC.solution-1.png b/docs/reference/FOMC.solution-1.png Binary files differindex 1d32355a..9d222d42 100644 --- a/docs/reference/FOMC.solution-1.png +++ b/docs/reference/FOMC.solution-1.png diff --git a/docs/reference/FOMC.solution.html b/docs/reference/FOMC.solution.html index 9136b882..9e3851fd 100644 --- a/docs/reference/FOMC.solution.html +++ b/docs/reference/FOMC.solution.html @@ -1,68 +1,13 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>First-Order Multi-Compartment kinetics — FOMC.solution • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="First-Order Multi-Compartment kinetics — FOMC.solution" /> -<meta property="og:description" content="Function describing exponential decline from a defined starting value, with -a decreasing rate constant." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>First-Order Multi-Compartment kinetics — FOMC.solution • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="First-Order Multi-Compartment kinetics — FOMC.solution"><meta property="og:description" content="Function describing exponential decline from a defined starting value, with +a decreasing rate constant."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -73,13 +18,12 @@ a decreasing rate constant." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -88,8 +32,7 @@ a decreasing rate constant." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -99,6 +42,9 @@ a decreasing rate constant." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -113,34 +59,27 @@ a decreasing rate constant." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>First-Order Multi-Compartment kinetics</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/parent_solutions.R'><code>R/parent_solutions.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/parent_solutions.R" class="external-link"><code>R/parent_solutions.R</code></a></small> <div class="hidden name"><code>FOMC.solution.Rd</code></div> </div> @@ -149,98 +88,94 @@ a decreasing rate constant." /> a decreasing rate constant.</p> </div> - <pre class="usage"><span class='fu'>FOMC.solution</span><span class='op'>(</span><span class='va'>t</span>, <span class='va'>parent_0</span>, <span class='va'>alpha</span>, <span class='va'>beta</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>t</th> - <td><p>Time.</p></td> - </tr> - <tr> - <th>parent_0</th> - <td><p>Starting value for the response variable at time zero.</p></td> - </tr> - <tr> - <th>alpha</th> - <td><p>Shape parameter determined by coefficient of variation of rate -constant values.</p></td> - </tr> - <tr> - <th>beta</th> - <td><p>Location parameter.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">FOMC.solution</span><span class="op">(</span><span class="va">t</span>, <span class="va">parent_0</span>, <span class="va">alpha</span>, <span class="va">beta</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>t</dt> +<dd><p>Time.</p></dd> +<dt>parent_0</dt> +<dd><p>Starting value for the response variable at time zero.</p></dd> +<dt>alpha</dt> +<dd><p>Shape parameter determined by coefficient of variation of rate +constant values.</p></dd> +<dt>beta</dt> +<dd><p>Location parameter.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The value of the response variable at time <code>t</code>.</p> - <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2> - + </div> + <div id="details"> + <h2>Details</h2> <p>The form given here differs slightly from the original reference by Gustafson and Holden (1990). The parameter <code>beta</code> corresponds to 1/beta in the original equation.</p> - <h2 class="hasAnchor" id="note"><a class="anchor" href="#note"></a>Note</h2> - + </div> + <div id="note"> + <h2>Note</h2> <p>The solution of the FOMC kinetic model reduces to the -<code><a href='SFO.solution.html'>SFO.solution</a></code> for large values of <code>alpha</code> and +<code><a href="SFO.solution.html">SFO.solution</a></code> for large values of <code>alpha</code> and <code>beta</code> with \(k = \frac{\beta}{\alpha}\).</p> - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - - <p>FOCUS (2006) “Guidance Document on Estimating Persistence + </div> + <div id="references"> + <h2>References</h2> + <p>FOCUS (2006) “Guidance Document on Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC Document Reference Sanco/10058/2005 version 2.0, 434 pp, -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> -<p>FOCUS (2014) “Generic guidance for Estimating Persistence +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> +<p>FOCUS (2014) “Generic guidance for Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, Version 1.1, 18 December 2014 -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> <p>Gustafson DI and Holden LR (1990) Nonlinear pesticide dissipation in soil: A new model based on spatial variability. <em>Environmental Science and Technology</em> <b>24</b>, 1032-1038</p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p>Other parent solutions: -<code><a href='DFOP.solution.html'>DFOP.solution</a>()</code>, -<code><a href='HS.solution.html'>HS.solution</a>()</code>, -<code><a href='IORE.solution.html'>IORE.solution</a>()</code>, -<code><a href='SFO.solution.html'>SFO.solution</a>()</code>, -<code><a href='SFORB.solution.html'>SFORB.solution</a>()</code>, -<code><a href='logistic.solution.html'>logistic.solution</a>()</code></p></div> - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> - <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='fu'>FOMC.solution</span><span class='op'>(</span><span class='va'>x</span>, <span class='fl'>100</span>, <span class='fl'>10</span>, <span class='fl'>2</span><span class='op'>)</span>, <span class='fl'>0</span>, <span class='fl'>2</span>, ylim <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>100</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='img'><img src='FOMC.solution-1.png' alt='' width='700' height='433' /></div><div class='input'> -</div></pre> + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p>Other parent solutions: +<code><a href="DFOP.solution.html">DFOP.solution</a>()</code>, +<code><a href="HS.solution.html">HS.solution</a>()</code>, +<code><a href="IORE.solution.html">IORE.solution</a>()</code>, +<code><a href="SFO.solution.html">SFO.solution</a>()</code>, +<code><a href="SFORB.solution.html">SFORB.solution</a>()</code>, +<code><a href="logistic.solution.html">logistic.solution</a>()</code></p></div> + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu">FOMC.solution</span><span class="op">(</span><span class="va">x</span>, <span class="fl">100</span>, <span class="fl">10</span>, <span class="fl">2</span><span class="op">)</span>, <span class="fl">0</span>, <span class="fl">2</span>, ylim <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">100</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-plt img"><img src="FOMC.solution-1.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/HS.solution-1.png b/docs/reference/HS.solution-1.png Binary files differindex 32d04b2d..dd7a76c8 100644 --- a/docs/reference/HS.solution-1.png +++ b/docs/reference/HS.solution-1.png diff --git a/docs/reference/HS.solution.html b/docs/reference/HS.solution.html index e3009bcc..7f0ab8ea 100644 --- a/docs/reference/HS.solution.html +++ b/docs/reference/HS.solution.html @@ -1,68 +1,13 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Hockey-Stick kinetics — HS.solution • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Hockey-Stick kinetics — HS.solution" /> -<meta property="og:description" content="Function describing two exponential decline functions with a break point -between them." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Hockey-Stick kinetics — HS.solution • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Hockey-Stick kinetics — HS.solution"><meta property="og:description" content="Function describing two exponential decline functions with a break point +between them."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -73,13 +18,12 @@ between them." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -88,8 +32,7 @@ between them." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -99,6 +42,9 @@ between them." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -113,34 +59,27 @@ between them." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Hockey-Stick kinetics</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/parent_solutions.R'><code>R/parent_solutions.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/parent_solutions.R" class="external-link"><code>R/parent_solutions.R</code></a></small> <div class="hidden name"><code>HS.solution.Rd</code></div> </div> @@ -149,90 +88,82 @@ between them." /> between them.</p> </div> - <pre class="usage"><span class='fu'>HS.solution</span><span class='op'>(</span><span class='va'>t</span>, <span class='va'>parent_0</span>, <span class='va'>k1</span>, <span class='va'>k2</span>, <span class='va'>tb</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>t</th> - <td><p>Time.</p></td> - </tr> - <tr> - <th>parent_0</th> - <td><p>Starting value for the response variable at time zero.</p></td> - </tr> - <tr> - <th>k1</th> - <td><p>First kinetic constant.</p></td> - </tr> - <tr> - <th>k2</th> - <td><p>Second kinetic constant.</p></td> - </tr> - <tr> - <th>tb</th> - <td><p>Break point. Before this time, exponential decline according to -<code>k1</code> is calculated, after this time, exponential decline proceeds -according to <code>k2</code>.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">HS.solution</span><span class="op">(</span><span class="va">t</span>, <span class="va">parent_0</span>, <span class="va">k1</span>, <span class="va">k2</span>, <span class="va">tb</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>t</dt> +<dd><p>Time.</p></dd> +<dt>parent_0</dt> +<dd><p>Starting value for the response variable at time zero.</p></dd> +<dt>k1</dt> +<dd><p>First kinetic constant.</p></dd> +<dt>k2</dt> +<dd><p>Second kinetic constant.</p></dd> +<dt>tb</dt> +<dd><p>Break point. Before this time, exponential decline according to +<code>k1</code> is calculated, after this time, exponential decline proceeds +according to <code>k2</code>.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The value of the response variable at time <code>t</code>.</p> - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - - <p>FOCUS (2006) “Guidance Document on Estimating Persistence + </div> + <div id="references"> + <h2>References</h2> + <p>FOCUS (2006) “Guidance Document on Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC Document Reference Sanco/10058/2005 version 2.0, 434 pp, -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a> -FOCUS (2014) “Generic guidance for Estimating Persistence +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a> +FOCUS (2014) “Generic guidance for Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, Version 1.1, 18 December 2014 -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p>Other parent solutions: -<code><a href='DFOP.solution.html'>DFOP.solution</a>()</code>, -<code><a href='FOMC.solution.html'>FOMC.solution</a>()</code>, -<code><a href='IORE.solution.html'>IORE.solution</a>()</code>, -<code><a href='SFO.solution.html'>SFO.solution</a>()</code>, -<code><a href='SFORB.solution.html'>SFORB.solution</a>()</code>, -<code><a href='logistic.solution.html'>logistic.solution</a>()</code></p></div> - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> - <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='fu'>HS.solution</span><span class='op'>(</span><span class='va'>x</span>, <span class='fl'>100</span>, <span class='fl'>2</span>, <span class='fl'>0.3</span>, <span class='fl'>0.5</span><span class='op'>)</span>, <span class='fl'>0</span>, <span class='fl'>2</span>, ylim<span class='op'>=</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0</span>,<span class='fl'>100</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='img'><img src='HS.solution-1.png' alt='' width='700' height='433' /></div><div class='input'> -</div></pre> +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p>Other parent solutions: +<code><a href="DFOP.solution.html">DFOP.solution</a>()</code>, +<code><a href="FOMC.solution.html">FOMC.solution</a>()</code>, +<code><a href="IORE.solution.html">IORE.solution</a>()</code>, +<code><a href="SFO.solution.html">SFO.solution</a>()</code>, +<code><a href="SFORB.solution.html">SFORB.solution</a>()</code>, +<code><a href="logistic.solution.html">logistic.solution</a>()</code></p></div> + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu">HS.solution</span><span class="op">(</span><span class="va">x</span>, <span class="fl">100</span>, <span class="fl">2</span>, <span class="fl">0.3</span>, <span class="fl">0.5</span><span class="op">)</span>, <span class="fl">0</span>, <span class="fl">2</span>, ylim<span class="op">=</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0</span>,<span class="fl">100</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-plt img"><img src="HS.solution-1.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/IORE.solution-1.png b/docs/reference/IORE.solution-1.png Binary files differindex 42643a58..9b6ab58f 100644 --- a/docs/reference/IORE.solution-1.png +++ b/docs/reference/IORE.solution-1.png diff --git a/docs/reference/IORE.solution.html b/docs/reference/IORE.solution.html index f1a40d44..bfb69a40 100644 --- a/docs/reference/IORE.solution.html +++ b/docs/reference/IORE.solution.html @@ -1,68 +1,13 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Indeterminate order rate equation kinetics — IORE.solution • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Indeterminate order rate equation kinetics — IORE.solution" /> -<meta property="og:description" content="Function describing exponential decline from a defined starting value, with -a concentration dependent rate constant." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Indeterminate order rate equation kinetics — IORE.solution • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Indeterminate order rate equation kinetics — IORE.solution"><meta property="og:description" content="Function describing exponential decline from a defined starting value, with +a concentration dependent rate constant."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -73,13 +18,12 @@ a concentration dependent rate constant." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -88,8 +32,7 @@ a concentration dependent rate constant." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -99,6 +42,9 @@ a concentration dependent rate constant." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -113,34 +59,27 @@ a concentration dependent rate constant." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Indeterminate order rate equation kinetics</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/parent_solutions.R'><code>R/parent_solutions.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/parent_solutions.R" class="external-link"><code>R/parent_solutions.R</code></a></small> <div class="hidden name"><code>IORE.solution.Rd</code></div> </div> @@ -149,100 +88,97 @@ a concentration dependent rate constant." /> a concentration dependent rate constant.</p> </div> - <pre class="usage"><span class='fu'>IORE.solution</span><span class='op'>(</span><span class='va'>t</span>, <span class='va'>parent_0</span>, <span class='va'>k__iore</span>, <span class='va'>N</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>t</th> - <td><p>Time.</p></td> - </tr> - <tr> - <th>parent_0</th> - <td><p>Starting value for the response variable at time zero.</p></td> - </tr> - <tr> - <th>k__iore</th> - <td><p>Rate constant. Note that this depends on the concentration -units used.</p></td> - </tr> - <tr> - <th>N</th> - <td><p>Exponent describing the nonlinearity of the rate equation</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">IORE.solution</span><span class="op">(</span><span class="va">t</span>, <span class="va">parent_0</span>, <span class="va">k__iore</span>, <span class="va">N</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>t</dt> +<dd><p>Time.</p></dd> +<dt>parent_0</dt> +<dd><p>Starting value for the response variable at time zero.</p></dd> +<dt>k__iore</dt> +<dd><p>Rate constant. Note that this depends on the concentration +units used.</p></dd> +<dt>N</dt> +<dd><p>Exponent describing the nonlinearity of the rate equation</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The value of the response variable at time <code>t</code>.</p> - <h2 class="hasAnchor" id="note"><a class="anchor" href="#note"></a>Note</h2> - + </div> + <div id="note"> + <h2>Note</h2> <p>The solution of the IORE kinetic model reduces to the -<code><a href='SFO.solution.html'>SFO.solution</a></code> if N = 1. The parameters of the IORE model can +<code><a href="SFO.solution.html">SFO.solution</a></code> if N = 1. The parameters of the IORE model can be transformed to equivalent parameters of the FOMC mode - see the NAFTA guidance for details.</p> - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - + </div> + <div id="references"> + <h2>References</h2> <p>NAFTA Technical Working Group on Pesticides (not dated) Guidance for Evaluating and Calculating Degradation Kinetics in Environmental Media</p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p>Other parent solutions: -<code><a href='DFOP.solution.html'>DFOP.solution</a>()</code>, -<code><a href='FOMC.solution.html'>FOMC.solution</a>()</code>, -<code><a href='HS.solution.html'>HS.solution</a>()</code>, -<code><a href='SFO.solution.html'>SFO.solution</a>()</code>, -<code><a href='SFORB.solution.html'>SFORB.solution</a>()</code>, -<code><a href='logistic.solution.html'>logistic.solution</a>()</code></p></div> - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> - <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='fu'>IORE.solution</span><span class='op'>(</span><span class='va'>x</span>, <span class='fl'>100</span>, <span class='fl'>0.2</span>, <span class='fl'>1.3</span><span class='op'>)</span>, <span class='fl'>0</span>, <span class='fl'>2</span>, ylim <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>100</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='img'><img src='IORE.solution-1.png' alt='' width='700' height='433' /></div><div class='input'> <span class='co'># \dontrun{</span> - <span class='va'>fit.fomc</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"FOMC"</span>, <span class='va'>FOCUS_2006_C</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - <span class='va'>fit.iore</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"IORE"</span>, <span class='va'>FOCUS_2006_C</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - <span class='va'>fit.iore.deS</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"IORE"</span>, <span class='va'>FOCUS_2006_C</span>, solution_type <span class='op'>=</span> <span class='st'>"deSolve"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - - <span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/data.frame.html'>data.frame</a></span><span class='op'>(</span><span class='va'>fit.fomc</span><span class='op'>$</span><span class='va'>par</span>, <span class='va'>fit.iore</span><span class='op'>$</span><span class='va'>par</span>, <span class='va'>fit.iore.deS</span><span class='op'>$</span><span class='va'>par</span>, - row.names <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/paste.html'>paste</a></span><span class='op'>(</span><span class='st'>"model par"</span>, <span class='fl'>1</span><span class='op'>:</span><span class='fl'>4</span><span class='op'>)</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> fit.fomc.par fit.iore.par fit.iore.deS.par -#> model par 1 85.87489063 85.874890 85.874890 -#> model par 2 0.05192238 -4.826631 -4.826631 -#> model par 3 0.65096665 1.949403 1.949403 -#> model par 4 1.85744396 1.857444 1.857444</div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/cbind.html'>rbind</a></span><span class='op'>(</span>fomc <span class='op'>=</span> <span class='fu'><a href='endpoints.html'>endpoints</a></span><span class='op'>(</span><span class='va'>fit.fomc</span><span class='op'>)</span><span class='op'>$</span><span class='va'>distimes</span>, iore <span class='op'>=</span> <span class='fu'><a href='endpoints.html'>endpoints</a></span><span class='op'>(</span><span class='va'>fit.iore</span><span class='op'>)</span><span class='op'>$</span><span class='va'>distimes</span>, - iore.deS <span class='op'>=</span> <span class='fu'><a href='endpoints.html'>endpoints</a></span><span class='op'>(</span><span class='va'>fit.iore</span><span class='op'>)</span><span class='op'>$</span><span class='va'>distimes</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> DT50 DT90 DT50back -#> fomc 1.785233 15.1479 4.559973 -#> iore 1.785233 15.1479 4.559973 -#> iore.deS 1.785233 15.1479 4.559973</div><div class='input'> <span class='co'># }</span> - -</div></pre> + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p>Other parent solutions: +<code><a href="DFOP.solution.html">DFOP.solution</a>()</code>, +<code><a href="FOMC.solution.html">FOMC.solution</a>()</code>, +<code><a href="HS.solution.html">HS.solution</a>()</code>, +<code><a href="SFO.solution.html">SFO.solution</a>()</code>, +<code><a href="SFORB.solution.html">SFORB.solution</a>()</code>, +<code><a href="logistic.solution.html">logistic.solution</a>()</code></p></div> + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu">IORE.solution</span><span class="op">(</span><span class="va">x</span>, <span class="fl">100</span>, <span class="fl">0.2</span>, <span class="fl">1.3</span><span class="op">)</span>, <span class="fl">0</span>, <span class="fl">2</span>, ylim <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">100</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-plt img"><img src="IORE.solution-1.png" alt="" width="700" height="433"></span> +<span class="r-in"> <span class="co"># \dontrun{</span></span> +<span class="r-in"> <span class="va">fit.fomc</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"FOMC"</span>, <span class="va">FOCUS_2006_C</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">fit.iore</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"IORE"</span>, <span class="va">FOCUS_2006_C</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">fit.iore.deS</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"IORE"</span>, <span class="va">FOCUS_2006_C</span>, solution_type <span class="op">=</span> <span class="st">"deSolve"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/data.frame.html" class="external-link">data.frame</a></span><span class="op">(</span><span class="va">fit.fomc</span><span class="op">$</span><span class="va">par</span>, <span class="va">fit.iore</span><span class="op">$</span><span class="va">par</span>, <span class="va">fit.iore.deS</span><span class="op">$</span><span class="va">par</span>, </span> +<span class="r-in"> row.names <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste</a></span><span class="op">(</span><span class="st">"model par"</span>, <span class="fl">1</span><span class="op">:</span><span class="fl">4</span><span class="op">)</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> fit.fomc.par fit.iore.par fit.iore.deS.par</span> +<span class="r-out co"><span class="r-pr">#></span> model par 1 85.87489063 85.874890 85.874890</span> +<span class="r-out co"><span class="r-pr">#></span> model par 2 0.05192238 -4.826631 -4.826631</span> +<span class="r-out co"><span class="r-pr">#></span> model par 3 0.65096665 1.949403 1.949403</span> +<span class="r-out co"><span class="r-pr">#></span> model par 4 1.85744396 1.857444 1.857444</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/cbind.html" class="external-link">rbind</a></span><span class="op">(</span>fomc <span class="op">=</span> <span class="fu"><a href="endpoints.html">endpoints</a></span><span class="op">(</span><span class="va">fit.fomc</span><span class="op">)</span><span class="op">$</span><span class="va">distimes</span>, iore <span class="op">=</span> <span class="fu"><a href="endpoints.html">endpoints</a></span><span class="op">(</span><span class="va">fit.iore</span><span class="op">)</span><span class="op">$</span><span class="va">distimes</span>, </span> +<span class="r-in"> iore.deS <span class="op">=</span> <span class="fu"><a href="endpoints.html">endpoints</a></span><span class="op">(</span><span class="va">fit.iore</span><span class="op">)</span><span class="op">$</span><span class="va">distimes</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90 DT50back</span> +<span class="r-out co"><span class="r-pr">#></span> fomc 1.785233 15.1479 4.559973</span> +<span class="r-out co"><span class="r-pr">#></span> iore 1.785233 15.1479 4.559973</span> +<span class="r-out co"><span class="r-pr">#></span> iore.deS 1.785233 15.1479 4.559973</span> +<span class="r-in"> <span class="co"># }</span></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/NAFTA_SOP_2015-1.png b/docs/reference/NAFTA_SOP_2015-1.png Binary files differindex 4f0d7833..5d2d434b 100644 --- a/docs/reference/NAFTA_SOP_2015-1.png +++ b/docs/reference/NAFTA_SOP_2015-1.png diff --git a/docs/reference/NAFTA_SOP_2015.html b/docs/reference/NAFTA_SOP_2015.html index de9db9eb..1862580b 100644 --- a/docs/reference/NAFTA_SOP_2015.html +++ b/docs/reference/NAFTA_SOP_2015.html @@ -1,67 +1,12 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Example datasets from the NAFTA SOP published 2015 — NAFTA_SOP_2015 • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Example datasets from the NAFTA SOP published 2015 — NAFTA_SOP_2015" /> -<meta property="og:description" content="Data taken from US EPA (2015), p. 19 and 23." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Example datasets from the NAFTA SOP published 2015 — NAFTA_SOP_2015 • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Example datasets from the NAFTA SOP published 2015 — NAFTA_SOP_2015"><meta property="og:description" content="Data taken from US EPA (2015), p. 19 and 23."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -72,13 +17,12 @@ </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -87,8 +31,7 @@ <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -98,6 +41,9 @@ <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -112,30 +58,23 @@ <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Example datasets from the NAFTA SOP published 2015</h1> @@ -147,97 +86,107 @@ <p>Data taken from US EPA (2015), p. 19 and 23.</p> </div> - <pre class="usage"><span class='va'>NAFTA_SOP_Appendix_B</span> - <span class='va'>NAFTA_SOP_Appendix_D</span></pre> - + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="va">NAFTA_SOP_Appendix_B</span> + <span class="va">NAFTA_SOP_Appendix_D</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2> + <div id="format"> + <h2>Format</h2> + <p>2 datasets with observations on the following variables.</p><dl><dt><code>name</code></dt> +<dd><p>a factor containing the name of the observed variable</p></dd> - <p>2 datasets with observations on the following variables.</p><dl> - <dt><code>name</code></dt><dd><p>a factor containing the name of the observed variable</p></dd> - <dt><code>time</code></dt><dd><p>a numeric vector containing time points</p></dd> - <dt><code>value</code></dt><dd><p>a numeric vector containing concentrations</p></dd> - -</dl> + <dt><code>time</code></dt> +<dd><p>a numeric vector containing time points</p></dd> - <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2> + <dt><code>value</code></dt> +<dd><p>a numeric vector containing concentrations</p></dd> + +</dl></div> + <div id="source"> + <h2>Source</h2> <p>NAFTA (2011) Guidance for evaluating and calculating degradation kinetics in environmental media. NAFTA Technical Working Group on Pesticides - <a href='https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/guidance-evaluating-and-calculating-degradation'>https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/guidance-evaluating-and-calculating-degradation</a> + <a href="https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/guidance-evaluating-and-calculating-degradation" class="external-link">https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/guidance-evaluating-and-calculating-degradation</a> accessed 2019-02-22</p> <p>US EPA (2015) Standard Operating Procedure for Using the NAFTA Guidance to Calculate Representative Half-life Values and Characterizing Pesticide Degradation - <a href='https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/standard-operating-procedure-using-nafta-guidance'>https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/standard-operating-procedure-using-nafta-guidance</a></p> - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> <span class='va'>nafta_evaluation</span> <span class='op'><-</span> <span class='fu'><a href='nafta.html'>nafta</a></span><span class='op'>(</span><span class='va'>NAFTA_SOP_Appendix_D</span>, cores <span class='op'>=</span> <span class='fl'>1</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>The SFO model is rejected as S_SFO is equal or higher than the critical value S_c</span></div><div class='output co'>#> <span class='message'>The representative half-life of the IORE model is longer than the one corresponding</span></div><div class='output co'>#> <span class='message'>to the terminal degradation rate found with the DFOP model.</span></div><div class='output co'>#> <span class='message'>The representative half-life obtained from the DFOP model may be used</span></div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>nafta_evaluation</span><span class='op'>)</span> -</div><div class='output co'>#> Sums of squares: -#> SFO IORE DFOP -#> 1378.6832 615.7730 517.8836 -#> -#> Critical sum of squares for checking the SFO model: -#> [1] 717.4598 -#> -#> Parameters: -#> $SFO -#> Estimate Pr(>t) Lower Upper -#> parent_0 83.7558 1.80e-14 77.18268 90.3288 -#> k_parent 0.0017 7.43e-05 0.00112 0.0026 -#> sigma 8.7518 1.22e-05 5.64278 11.8608 -#> -#> $IORE -#> Estimate Pr(>t) Lower Upper -#> parent_0 9.69e+01 NA 8.88e+01 1.05e+02 -#> k__iore_parent 8.40e-14 NA 1.79e-18 3.94e-09 -#> N_parent 6.68e+00 NA 4.19e+00 9.17e+00 -#> sigma 5.85e+00 NA 3.76e+00 7.94e+00 -#> -#> $DFOP -#> Estimate Pr(>t) Lower Upper -#> parent_0 9.76e+01 1.94e-13 9.02e+01 1.05e+02 -#> k1 4.24e-02 5.92e-03 2.03e-02 8.88e-02 -#> k2 8.24e-04 6.48e-03 3.89e-04 1.75e-03 -#> g 2.88e-01 2.47e-05 1.95e-01 4.03e-01 -#> sigma 5.36e+00 2.22e-05 3.43e+00 7.30e+00 -#> -#> -#> DTx values: -#> DT50 DT90 DT50_rep -#> SFO 407 1350 407 -#> IORE 541 5190000 1560000 -#> DFOP 429 2380 841 -#> -#> Representative half-life: -#> [1] 841.41</div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>nafta_evaluation</span><span class='op'>)</span> -</div><div class='img'><img src='NAFTA_SOP_2015-1.png' alt='' width='700' height='433' /></div></pre> + <a href="https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/standard-operating-procedure-using-nafta-guidance" class="external-link">https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/standard-operating-procedure-using-nafta-guidance</a></p> + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"> <span class="va">nafta_evaluation</span> <span class="op"><-</span> <span class="fu"><a href="nafta.html">nafta</a></span><span class="op">(</span><span class="va">NAFTA_SOP_Appendix_D</span>, cores <span class="op">=</span> <span class="fl">1</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> The SFO model is rejected as S_SFO is equal or higher than the critical value S_c</span> +<span class="r-msg co"><span class="r-pr">#></span> The representative half-life of the IORE model is longer than the one corresponding</span> +<span class="r-msg co"><span class="r-pr">#></span> to the terminal degradation rate found with the DFOP model.</span> +<span class="r-msg co"><span class="r-pr">#></span> The representative half-life obtained from the DFOP model may be used</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">nafta_evaluation</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Sums of squares:</span> +<span class="r-out co"><span class="r-pr">#></span> SFO IORE DFOP </span> +<span class="r-out co"><span class="r-pr">#></span> 1378.6832 615.7730 517.8836 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Critical sum of squares for checking the SFO model:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] 717.4598</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> $SFO</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 83.7558 1.80e-14 77.18268 90.3288</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.0017 7.43e-05 0.00112 0.0026</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 8.7518 1.22e-05 5.64278 11.8608</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $IORE</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 9.69e+01 NA 8.88e+01 1.05e+02</span> +<span class="r-out co"><span class="r-pr">#></span> k__iore_parent 8.40e-14 NA 1.79e-18 3.94e-09</span> +<span class="r-out co"><span class="r-pr">#></span> N_parent 6.68e+00 NA 4.19e+00 9.17e+00</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 5.85e+00 NA 3.76e+00 7.94e+00</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $DFOP</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 9.76e+01 1.94e-13 9.02e+01 1.05e+02</span> +<span class="r-out co"><span class="r-pr">#></span> k1 4.24e-02 5.92e-03 2.03e-02 8.88e-02</span> +<span class="r-out co"><span class="r-pr">#></span> k2 8.24e-04 6.48e-03 3.89e-04 1.75e-03</span> +<span class="r-out co"><span class="r-pr">#></span> g 2.88e-01 2.47e-05 1.95e-01 4.03e-01</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 5.36e+00 2.22e-05 3.43e+00 7.30e+00</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> DTx values:</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90 DT50_rep</span> +<span class="r-out co"><span class="r-pr">#></span> SFO 407 1350 407</span> +<span class="r-out co"><span class="r-pr">#></span> IORE 541 5190000 1560000</span> +<span class="r-out co"><span class="r-pr">#></span> DFOP 429 2380 841</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Representative half-life:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] 841.41</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">nafta_evaluation</span><span class="op">)</span></span> +<span class="r-plt img"><img src="NAFTA_SOP_2015-1.png" alt="" width="700" height="433"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/NAFTA_SOP_Attachment-1.png b/docs/reference/NAFTA_SOP_Attachment-1.png Binary files differindex 9417685e..d8951fc3 100644 --- a/docs/reference/NAFTA_SOP_Attachment-1.png +++ b/docs/reference/NAFTA_SOP_Attachment-1.png diff --git a/docs/reference/NAFTA_SOP_Attachment.html b/docs/reference/NAFTA_SOP_Attachment.html index 0b063e2c..e602a2b0 100644 --- a/docs/reference/NAFTA_SOP_Attachment.html +++ b/docs/reference/NAFTA_SOP_Attachment.html @@ -1,67 +1,12 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Example datasets from Attachment 1 to the NAFTA SOP published 2015 — NAFTA_SOP_Attachment • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Example datasets from Attachment 1 to the NAFTA SOP published 2015 — NAFTA_SOP_Attachment" /> -<meta property="og:description" content="Data taken from from Attachment 1 of the SOP." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Example datasets from Attachment 1 to the NAFTA SOP published 2015 — NAFTA_SOP_Attachment • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Example datasets from Attachment 1 to the NAFTA SOP published 2015 — NAFTA_SOP_Attachment"><meta property="og:description" content="Data taken from from Attachment 1 of the SOP."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -72,13 +17,12 @@ </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -87,8 +31,7 @@ <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -98,6 +41,9 @@ <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -112,30 +58,23 @@ <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Example datasets from Attachment 1 to the NAFTA SOP published 2015</h1> @@ -147,91 +86,96 @@ <p>Data taken from from Attachment 1 of the SOP.</p> </div> - <pre class="usage"><span class='va'>NAFTA_SOP_Attachment</span></pre> - - - <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="va">NAFTA_SOP_Attachment</span></code></pre></div> + </div> + <div id="format"> + <h2>Format</h2> <p>A list (NAFTA_SOP_Attachment) containing 16 datasets suitable - for the evaluation with <code><a href='nafta.html'>nafta</a></code></p> - <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2> - + for the evaluation with <code><a href="nafta.html">nafta</a></code></p> + </div> + <div id="source"> + <h2>Source</h2> <p>NAFTA (2011) Guidance for evaluating and calculating degradation kinetics in environmental media. NAFTA Technical Working Group on Pesticides - <a href='https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/guidance-evaluating-and-calculating-degradation'>https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/guidance-evaluating-and-calculating-degradation</a> + <a href="https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/guidance-evaluating-and-calculating-degradation" class="external-link">https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/guidance-evaluating-and-calculating-degradation</a> accessed 2019-02-22</p> <p>US EPA (2015) Standard Operating Procedure for Using the NAFTA Guidance to Calculate Representative Half-life Values and Characterizing Pesticide Degradation - <a href='https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/standard-operating-procedure-using-nafta-guidance'>https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/standard-operating-procedure-using-nafta-guidance</a></p> - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> <span class='va'>nafta_att_p5a</span> <span class='op'><-</span> <span class='fu'><a href='nafta.html'>nafta</a></span><span class='op'>(</span><span class='va'>NAFTA_SOP_Attachment</span><span class='op'>[[</span><span class='st'>"p5a"</span><span class='op'>]</span><span class='op'>]</span>, cores <span class='op'>=</span> <span class='fl'>1</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>The SFO model is rejected as S_SFO is equal or higher than the critical value S_c</span></div><div class='output co'>#> <span class='message'>The half-life obtained from the IORE model may be used</span></div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>nafta_att_p5a</span><span class='op'>)</span> -</div><div class='output co'>#> Sums of squares: -#> SFO IORE DFOP -#> 465.21753 56.27506 32.06401 -#> -#> Critical sum of squares for checking the SFO model: -#> [1] 64.4304 -#> -#> Parameters: -#> $SFO -#> Estimate Pr(>t) Lower Upper -#> parent_0 95.8401 4.67e-21 92.245 99.4357 -#> k_parent 0.0102 3.92e-12 0.009 0.0117 -#> sigma 4.8230 3.81e-06 3.214 6.4318 -#> -#> $IORE -#> Estimate Pr(>t) Lower Upper -#> parent_0 1.01e+02 NA 9.91e+01 1.02e+02 -#> k__iore_parent 1.54e-05 NA 4.08e-06 5.84e-05 -#> N_parent 2.57e+00 NA 2.25e+00 2.89e+00 -#> sigma 1.68e+00 NA 1.12e+00 2.24e+00 -#> -#> $DFOP -#> Estimate Pr(>t) Lower Upper -#> parent_0 9.99e+01 1.41e-26 98.8116 101.0810 -#> k1 2.67e-02 5.05e-06 0.0243 0.0295 -#> k2 2.26e-12 5.00e-01 0.0000 Inf -#> g 6.47e-01 3.67e-06 0.6248 0.6677 -#> sigma 1.27e+00 8.91e-06 0.8395 1.6929 -#> -#> -#> DTx values: -#> DT50 DT90 DT50_rep -#> SFO 67.7 2.25e+02 6.77e+01 -#> IORE 58.2 1.07e+03 3.22e+02 -#> DFOP 55.5 5.59e+11 3.07e+11 -#> -#> Representative half-life: -#> [1] 321.51</div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>nafta_att_p5a</span><span class='op'>)</span> -</div><div class='img'><img src='NAFTA_SOP_Attachment-1.png' alt='' width='700' height='433' /></div></pre> + <a href="https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/standard-operating-procedure-using-nafta-guidance" class="external-link">https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/standard-operating-procedure-using-nafta-guidance</a></p> + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"> <span class="va">nafta_att_p5a</span> <span class="op"><-</span> <span class="fu"><a href="nafta.html">nafta</a></span><span class="op">(</span><span class="va">NAFTA_SOP_Attachment</span><span class="op">[[</span><span class="st">"p5a"</span><span class="op">]</span><span class="op">]</span>, cores <span class="op">=</span> <span class="fl">1</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> The SFO model is rejected as S_SFO is equal or higher than the critical value S_c</span> +<span class="r-msg co"><span class="r-pr">#></span> The half-life obtained from the IORE model may be used</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">nafta_att_p5a</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Sums of squares:</span> +<span class="r-out co"><span class="r-pr">#></span> SFO IORE DFOP </span> +<span class="r-out co"><span class="r-pr">#></span> 465.21753 56.27506 32.06401 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Critical sum of squares for checking the SFO model:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] 64.4304</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> $SFO</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 95.8401 4.67e-21 92.245 99.4357</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.0102 3.92e-12 0.009 0.0117</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 4.8230 3.81e-06 3.214 6.4318</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $IORE</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 1.01e+02 NA 9.91e+01 1.02e+02</span> +<span class="r-out co"><span class="r-pr">#></span> k__iore_parent 1.54e-05 NA 4.08e-06 5.84e-05</span> +<span class="r-out co"><span class="r-pr">#></span> N_parent 2.57e+00 NA 2.25e+00 2.89e+00</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 1.68e+00 NA 1.12e+00 2.24e+00</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $DFOP</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 9.99e+01 1.41e-26 98.8116 101.0810</span> +<span class="r-out co"><span class="r-pr">#></span> k1 2.67e-02 5.05e-06 0.0243 0.0295</span> +<span class="r-out co"><span class="r-pr">#></span> k2 2.26e-12 5.00e-01 0.0000 Inf</span> +<span class="r-out co"><span class="r-pr">#></span> g 6.47e-01 3.67e-06 0.6248 0.6677</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 1.27e+00 8.91e-06 0.8395 1.6929</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> DTx values:</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90 DT50_rep</span> +<span class="r-out co"><span class="r-pr">#></span> SFO 67.7 2.25e+02 6.77e+01</span> +<span class="r-out co"><span class="r-pr">#></span> IORE 58.2 1.07e+03 3.22e+02</span> +<span class="r-out co"><span class="r-pr">#></span> DFOP 55.5 5.59e+11 3.07e+11</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Representative half-life:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] 321.51</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">nafta_att_p5a</span><span class="op">)</span></span> +<span class="r-plt img"><img src="NAFTA_SOP_Attachment-1.png" alt="" width="700" height="433"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/Rplot001.png b/docs/reference/Rplot001.png Binary files differindex 22eb54d3..88d4c784 100644 --- a/docs/reference/Rplot001.png +++ b/docs/reference/Rplot001.png diff --git a/docs/reference/Rplot002.png b/docs/reference/Rplot002.png Binary files differindex 8512d4f8..86d1775b 100644 --- a/docs/reference/Rplot002.png +++ b/docs/reference/Rplot002.png diff --git a/docs/reference/Rplot003.png b/docs/reference/Rplot003.png Binary files differindex da0a093b..b1cdfcc9 100644 --- a/docs/reference/Rplot003.png +++ b/docs/reference/Rplot003.png diff --git a/docs/reference/Rplot004.png b/docs/reference/Rplot004.png Binary files differindex 31771c20..b91e73fb 100644 --- a/docs/reference/Rplot004.png +++ b/docs/reference/Rplot004.png diff --git a/docs/reference/Rplot005.png b/docs/reference/Rplot005.png Binary files differindex 31771c20..76f25647 100644 --- a/docs/reference/Rplot005.png +++ b/docs/reference/Rplot005.png diff --git a/docs/reference/Rplot006.png b/docs/reference/Rplot006.png Binary files differindex 4c728f4e..48f5bbd8 100644 --- a/docs/reference/Rplot006.png +++ b/docs/reference/Rplot006.png diff --git a/docs/reference/Rplot007.png b/docs/reference/Rplot007.png Binary files differindex 3405a171..21a6ea76 100644 --- a/docs/reference/Rplot007.png +++ b/docs/reference/Rplot007.png diff --git a/docs/reference/SFO.solution-1.png b/docs/reference/SFO.solution-1.png Binary files differindex 56d27ef6..a00499cb 100644 --- a/docs/reference/SFO.solution-1.png +++ b/docs/reference/SFO.solution-1.png diff --git a/docs/reference/SFO.solution.html b/docs/reference/SFO.solution.html index 826a0472..8caa8958 100644 --- a/docs/reference/SFO.solution.html +++ b/docs/reference/SFO.solution.html @@ -1,67 +1,12 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Single First-Order kinetics — SFO.solution • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Single First-Order kinetics — SFO.solution" /> -<meta property="og:description" content="Function describing exponential decline from a defined starting value." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Single First-Order kinetics — SFO.solution • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Single First-Order kinetics — SFO.solution"><meta property="og:description" content="Function describing exponential decline from a defined starting value."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -72,13 +17,12 @@ </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -87,8 +31,7 @@ <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -98,6 +41,9 @@ <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -112,34 +58,27 @@ <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Single First-Order kinetics</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/parent_solutions.R'><code>R/parent_solutions.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/parent_solutions.R" class="external-link"><code>R/parent_solutions.R</code></a></small> <div class="hidden name"><code>SFO.solution.Rd</code></div> </div> @@ -147,80 +86,76 @@ <p>Function describing exponential decline from a defined starting value.</p> </div> - <pre class="usage"><span class='fu'>SFO.solution</span><span class='op'>(</span><span class='va'>t</span>, <span class='va'>parent_0</span>, <span class='va'>k</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>t</th> - <td><p>Time.</p></td> - </tr> - <tr> - <th>parent_0</th> - <td><p>Starting value for the response variable at time zero.</p></td> - </tr> - <tr> - <th>k</th> - <td><p>Kinetic rate constant.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">SFO.solution</span><span class="op">(</span><span class="va">t</span>, <span class="va">parent_0</span>, <span class="va">k</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>t</dt> +<dd><p>Time.</p></dd> +<dt>parent_0</dt> +<dd><p>Starting value for the response variable at time zero.</p></dd> +<dt>k</dt> +<dd><p>Kinetic rate constant.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The value of the response variable at time <code>t</code>.</p> - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - - <p>FOCUS (2006) “Guidance Document on Estimating Persistence + </div> + <div id="references"> + <h2>References</h2> + <p>FOCUS (2006) “Guidance Document on Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC Document Reference Sanco/10058/2005 version 2.0, 434 pp, -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a> -FOCUS (2014) “Generic guidance for Estimating Persistence +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a> +FOCUS (2014) “Generic guidance for Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, Version 1.1, 18 December 2014 -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p>Other parent solutions: -<code><a href='DFOP.solution.html'>DFOP.solution</a>()</code>, -<code><a href='FOMC.solution.html'>FOMC.solution</a>()</code>, -<code><a href='HS.solution.html'>HS.solution</a>()</code>, -<code><a href='IORE.solution.html'>IORE.solution</a>()</code>, -<code><a href='SFORB.solution.html'>SFORB.solution</a>()</code>, -<code><a href='logistic.solution.html'>logistic.solution</a>()</code></p></div> - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> - <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='fu'>SFO.solution</span><span class='op'>(</span><span class='va'>x</span>, <span class='fl'>100</span>, <span class='fl'>3</span><span class='op'>)</span>, <span class='fl'>0</span>, <span class='fl'>2</span><span class='op'>)</span> -</div><div class='img'><img src='SFO.solution-1.png' alt='' width='700' height='433' /></div><div class='input'> -</div></pre> +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p>Other parent solutions: +<code><a href="DFOP.solution.html">DFOP.solution</a>()</code>, +<code><a href="FOMC.solution.html">FOMC.solution</a>()</code>, +<code><a href="HS.solution.html">HS.solution</a>()</code>, +<code><a href="IORE.solution.html">IORE.solution</a>()</code>, +<code><a href="SFORB.solution.html">SFORB.solution</a>()</code>, +<code><a href="logistic.solution.html">logistic.solution</a>()</code></p></div> + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu">SFO.solution</span><span class="op">(</span><span class="va">x</span>, <span class="fl">100</span>, <span class="fl">3</span><span class="op">)</span>, <span class="fl">0</span>, <span class="fl">2</span><span class="op">)</span></span> +<span class="r-plt img"><img src="SFO.solution-1.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/SFORB.solution-1.png b/docs/reference/SFORB.solution-1.png Binary files differindex 4eeb0d41..7bea3b78 100644 --- a/docs/reference/SFORB.solution-1.png +++ b/docs/reference/SFORB.solution-1.png diff --git a/docs/reference/SFORB.solution.html b/docs/reference/SFORB.solution.html index b2062e30..45933071 100644 --- a/docs/reference/SFORB.solution.html +++ b/docs/reference/SFORB.solution.html @@ -1,71 +1,16 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Single First-Order Reversible Binding kinetics — SFORB.solution • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Single First-Order Reversible Binding kinetics — SFORB.solution" /> -<meta property="og:description" content="Function describing the solution of the differential equations describing +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Single First-Order Reversible Binding kinetics — SFORB.solution • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Single First-Order Reversible Binding kinetics — SFORB.solution"><meta property="og:description" content="Function describing the solution of the differential equations describing the kinetic model with first-order terms for a two-way transfer from a free to a bound fraction, and a first-order degradation term for the free fraction. The initial condition is a defined amount in the free fraction -and no substance in the bound fraction." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +and no substance in the bound fraction."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -76,13 +21,12 @@ and no substance in the bound fraction." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -91,8 +35,7 @@ and no substance in the bound fraction." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -102,6 +45,9 @@ and no substance in the bound fraction." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -116,34 +62,27 @@ and no substance in the bound fraction." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Single First-Order Reversible Binding kinetics</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/parent_solutions.R'><code>R/parent_solutions.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/parent_solutions.R" class="external-link"><code>R/parent_solutions.R</code></a></small> <div class="hidden name"><code>SFORB.solution.Rd</code></div> </div> @@ -155,90 +94,82 @@ fraction. The initial condition is a defined amount in the free fraction and no substance in the bound fraction.</p> </div> - <pre class="usage"><span class='fu'>SFORB.solution</span><span class='op'>(</span><span class='va'>t</span>, <span class='va'>parent_0</span>, <span class='va'>k_12</span>, <span class='va'>k_21</span>, <span class='va'>k_1output</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>t</th> - <td><p>Time.</p></td> - </tr> - <tr> - <th>parent_0</th> - <td><p>Starting value for the response variable at time zero.</p></td> - </tr> - <tr> - <th>k_12</th> - <td><p>Kinetic constant describing transfer from free to bound.</p></td> - </tr> - <tr> - <th>k_21</th> - <td><p>Kinetic constant describing transfer from bound to free.</p></td> - </tr> - <tr> - <th>k_1output</th> - <td><p>Kinetic constant describing degradation of the free -fraction.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">SFORB.solution</span><span class="op">(</span><span class="va">t</span>, <span class="va">parent_0</span>, <span class="va">k_12</span>, <span class="va">k_21</span>, <span class="va">k_1output</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>t</dt> +<dd><p>Time.</p></dd> +<dt>parent_0</dt> +<dd><p>Starting value for the response variable at time zero.</p></dd> +<dt>k_12</dt> +<dd><p>Kinetic constant describing transfer from free to bound.</p></dd> +<dt>k_21</dt> +<dd><p>Kinetic constant describing transfer from bound to free.</p></dd> +<dt>k_1output</dt> +<dd><p>Kinetic constant describing degradation of the free +fraction.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The value of the response variable, which is the sum of free and bound fractions at time <code>t</code>.</p> - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - - <p>FOCUS (2006) “Guidance Document on Estimating Persistence + </div> + <div id="references"> + <h2>References</h2> + <p>FOCUS (2006) “Guidance Document on Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC Document Reference Sanco/10058/2005 version 2.0, 434 pp, -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a> -FOCUS (2014) “Generic guidance for Estimating Persistence +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a> +FOCUS (2014) “Generic guidance for Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, Version 1.1, 18 December 2014 -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p>Other parent solutions: -<code><a href='DFOP.solution.html'>DFOP.solution</a>()</code>, -<code><a href='FOMC.solution.html'>FOMC.solution</a>()</code>, -<code><a href='HS.solution.html'>HS.solution</a>()</code>, -<code><a href='IORE.solution.html'>IORE.solution</a>()</code>, -<code><a href='SFO.solution.html'>SFO.solution</a>()</code>, -<code><a href='logistic.solution.html'>logistic.solution</a>()</code></p></div> - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> - <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='fu'>SFORB.solution</span><span class='op'>(</span><span class='va'>x</span>, <span class='fl'>100</span>, <span class='fl'>0.5</span>, <span class='fl'>2</span>, <span class='fl'>3</span><span class='op'>)</span>, <span class='fl'>0</span>, <span class='fl'>2</span><span class='op'>)</span> -</div><div class='img'><img src='SFORB.solution-1.png' alt='' width='700' height='433' /></div><div class='input'> -</div></pre> +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p>Other parent solutions: +<code><a href="DFOP.solution.html">DFOP.solution</a>()</code>, +<code><a href="FOMC.solution.html">FOMC.solution</a>()</code>, +<code><a href="HS.solution.html">HS.solution</a>()</code>, +<code><a href="IORE.solution.html">IORE.solution</a>()</code>, +<code><a href="SFO.solution.html">SFO.solution</a>()</code>, +<code><a href="logistic.solution.html">logistic.solution</a>()</code></p></div> + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu">SFORB.solution</span><span class="op">(</span><span class="va">x</span>, <span class="fl">100</span>, <span class="fl">0.5</span>, <span class="fl">2</span>, <span class="fl">3</span><span class="op">)</span>, <span class="fl">0</span>, <span class="fl">2</span><span class="op">)</span></span> +<span class="r-plt img"><img src="SFORB.solution-1.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/add_err-1.png b/docs/reference/add_err-1.png Binary files differindex 70118923..4a3b4062 100644 --- a/docs/reference/add_err-1.png +++ b/docs/reference/add_err-1.png diff --git a/docs/reference/add_err-2.png b/docs/reference/add_err-2.png Binary files differindex 69b820c2..5aec1744 100644 --- a/docs/reference/add_err-2.png +++ b/docs/reference/add_err-2.png diff --git a/docs/reference/add_err-3.png b/docs/reference/add_err-3.png Binary files differindex 1de78fa7..2e71f02f 100644 --- a/docs/reference/add_err-3.png +++ b/docs/reference/add_err-3.png diff --git a/docs/reference/add_err.html b/docs/reference/add_err.html index 18ca517e..50b55748 100644 --- a/docs/reference/add_err.html +++ b/docs/reference/add_err.html @@ -1,69 +1,14 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Add normally distributed errors to simulated kinetic degradation data — add_err • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Add normally distributed errors to simulated kinetic degradation data — add_err" /> -<meta property="og:description" content="Normally distributed errors are added to data predicted for a specific +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Add normally distributed errors to simulated kinetic degradation data — add_err • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Add normally distributed errors to simulated kinetic degradation data — add_err"><meta property="og:description" content="Normally distributed errors are added to data predicted for a specific degradation model using mkinpredict. The variance of the error -may depend on the predicted value and is specified as a standard deviation." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +may depend on the predicted value and is specified as a standard deviation."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -74,13 +19,12 @@ may depend on the predicted value and is specified as a standard deviation." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -89,8 +33,7 @@ may depend on the predicted value and is specified as a standard deviation." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -100,6 +43,9 @@ may depend on the predicted value and is specified as a standard deviation." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -114,181 +60,163 @@ may depend on the predicted value and is specified as a standard deviation." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Add normally distributed errors to simulated kinetic degradation data</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/add_err.R'><code>R/add_err.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/add_err.R" class="external-link"><code>R/add_err.R</code></a></small> <div class="hidden name"><code>add_err.Rd</code></div> </div> <div class="ref-description"> <p>Normally distributed errors are added to data predicted for a specific -degradation model using <code><a href='mkinpredict.html'>mkinpredict</a></code>. The variance of the error +degradation model using <code><a href="mkinpredict.html">mkinpredict</a></code>. The variance of the error may depend on the predicted value and is specified as a standard deviation.</p> </div> - <pre class="usage"><span class='fu'>add_err</span><span class='op'>(</span> - <span class='va'>prediction</span>, - <span class='va'>sdfunc</span>, - secondary <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"M1"</span>, <span class='st'>"M2"</span><span class='op'>)</span>, - n <span class='op'>=</span> <span class='fl'>10</span>, - LOD <span class='op'>=</span> <span class='fl'>0.1</span>, - reps <span class='op'>=</span> <span class='fl'>2</span>, - digits <span class='op'>=</span> <span class='fl'>1</span>, - seed <span class='op'>=</span> <span class='cn'>NA</span> -<span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">add_err</span><span class="op">(</span> + <span class="va">prediction</span>, + <span class="va">sdfunc</span>, + secondary <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"M1"</span>, <span class="st">"M2"</span><span class="op">)</span>, + n <span class="op">=</span> <span class="fl">10</span>, + LOD <span class="op">=</span> <span class="fl">0.1</span>, + reps <span class="op">=</span> <span class="fl">2</span>, + digits <span class="op">=</span> <span class="fl">1</span>, + seed <span class="op">=</span> <span class="cn">NA</span> +<span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>prediction</th> - <td><p>A prediction from a kinetic model as produced by -<code><a href='mkinpredict.html'>mkinpredict</a></code>.</p></td> - </tr> - <tr> - <th>sdfunc</th> - <td><p>A function taking the predicted value as its only argument and + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>prediction</dt> +<dd><p>A prediction from a kinetic model as produced by +<code><a href="mkinpredict.html">mkinpredict</a></code>.</p></dd> +<dt>sdfunc</dt> +<dd><p>A function taking the predicted value as its only argument and returning a standard deviation that should be used for generating the -random error terms for this value.</p></td> - </tr> - <tr> - <th>secondary</th> - <td><p>The names of state variables that should have an initial -value of zero</p></td> - </tr> - <tr> - <th>n</th> - <td><p>The number of datasets to be generated.</p></td> - </tr> - <tr> - <th>LOD</th> - <td><p>The limit of detection (LOD). Values that are below the LOD after -adding the random error will be set to NA.</p></td> - </tr> - <tr> - <th>reps</th> - <td><p>The number of replicates to be generated within the datasets.</p></td> - </tr> - <tr> - <th>digits</th> - <td><p>The number of digits to which the values will be rounded.</p></td> - </tr> - <tr> - <th>seed</th> - <td><p>The seed used for the generation of random numbers. If NA, the -seed is not set.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - - <p>A list of datasets compatible with <code><a href='mmkin.html'>mmkin</a></code>, i.e. the -components of the list are datasets compatible with <code><a href='mkinfit.html'>mkinfit</a></code>.</p> - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - +random error terms for this value.</p></dd> +<dt>secondary</dt> +<dd><p>The names of state variables that should have an initial +value of zero</p></dd> +<dt>n</dt> +<dd><p>The number of datasets to be generated.</p></dd> +<dt>LOD</dt> +<dd><p>The limit of detection (LOD). Values that are below the LOD after +adding the random error will be set to NA.</p></dd> +<dt>reps</dt> +<dd><p>The number of replicates to be generated within the datasets.</p></dd> +<dt>digits</dt> +<dd><p>The number of digits to which the values will be rounded.</p></dd> +<dt>seed</dt> +<dd><p>The seed used for the generation of random numbers. If NA, the +seed is not set.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>A list of datasets compatible with <code><a href="mmkin.html">mmkin</a></code>, i.e. the +components of the list are datasets compatible with <code><a href="mkinfit.html">mkinfit</a></code>.</p> + </div> + <div id="references"> + <h2>References</h2> <p>Ranke J and Lehmann R (2015) To t-test or not to t-test, that is the question. XV Symposium on Pesticide Chemistry 2-4 September 2015, Piacenza, Italy https://jrwb.de/posters/piacenza_2015.pdf</p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='co'># The kinetic model</span> -<span class='va'>m_SFO_SFO</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"M1"</span><span class='op'>)</span>, - M1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> -<span class='co'># Generate a prediction for a specific set of parameters</span> -<span class='va'>sampling_times</span> <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>1</span>, <span class='fl'>3</span>, <span class='fl'>7</span>, <span class='fl'>14</span>, <span class='fl'>28</span>, <span class='fl'>60</span>, <span class='fl'>90</span>, <span class='fl'>120</span><span class='op'>)</span> - -<span class='co'># This is the prediction used for the "Type 2 datasets" on the Piacenza poster</span> -<span class='co'># from 2015</span> -<span class='va'>d_SFO_SFO</span> <span class='op'><-</span> <span class='fu'><a href='mkinpredict.html'>mkinpredict</a></span><span class='op'>(</span><span class='va'>m_SFO_SFO</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_parent <span class='op'>=</span> <span class='fl'>0.1</span>, f_parent_to_M1 <span class='op'>=</span> <span class='fl'>0.5</span>, - k_M1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/Log.html'>log</a></span><span class='op'>(</span><span class='fl'>2</span><span class='op'>)</span><span class='op'>/</span><span class='fl'>1000</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>100</span>, M1 <span class='op'>=</span> <span class='fl'>0</span><span class='op'>)</span>, - <span class='va'>sampling_times</span><span class='op'>)</span> - -<span class='co'># Add an error term with a constant (independent of the value) standard deviation</span> -<span class='co'># of 10, and generate three datasets</span> -<span class='va'>d_SFO_SFO_err</span> <span class='op'><-</span> <span class='fu'>add_err</span><span class='op'>(</span><span class='va'>d_SFO_SFO</span>, <span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='fl'>10</span>, n <span class='op'>=</span> <span class='fl'>3</span>, seed <span class='op'>=</span> <span class='fl'>123456789</span> <span class='op'>)</span> - -<span class='co'># Name the datasets for nicer plotting</span> -<span class='fu'><a href='https://rdrr.io/r/base/names.html'>names</a></span><span class='op'>(</span><span class='va'>d_SFO_SFO_err</span><span class='op'>)</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/paste.html'>paste</a></span><span class='op'>(</span><span class='st'>"Dataset"</span>, <span class='fl'>1</span><span class='op'>:</span><span class='fl'>3</span><span class='op'>)</span> - -<span class='co'># Name the model in the list of models (with only one member in this case) for</span> -<span class='co'># nicer plotting later on. Be quiet and use only one core not to offend CRAN</span> -<span class='co'># checks</span> -<span class='co'># \dontrun{</span> -<span class='va'>f_SFO_SFO</span> <span class='op'><-</span> <span class='fu'><a href='mmkin.html'>mmkin</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span><span class='st'>"SFO-SFO"</span> <span class='op'>=</span> <span class='va'>m_SFO_SFO</span><span class='op'>)</span>, - <span class='va'>d_SFO_SFO_err</span>, cores <span class='op'>=</span> <span class='fl'>1</span>, - quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - -<span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>f_SFO_SFO</span><span class='op'>)</span> -</div><div class='img'><img src='add_err-1.png' alt='' width='700' height='433' /></div><div class='input'> -<span class='co'># We would like to inspect the fit for dataset 3 more closely</span> -<span class='co'># Using double brackets makes the returned object an mkinfit object</span> -<span class='co'># instead of a list of mkinfit objects, so plot.mkinfit is used</span> -<span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>f_SFO_SFO</span><span class='op'>[[</span><span class='fl'>3</span><span class='op'>]</span><span class='op'>]</span>, show_residuals <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='img'><img src='add_err-2.png' alt='' width='700' height='433' /></div><div class='input'> -<span class='co'># If we use single brackets, we should give two indices (model and dataset),</span> -<span class='co'># and plot.mmkin is used</span> -<span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>f_SFO_SFO</span><span class='op'>[</span><span class='fl'>1</span>, <span class='fl'>3</span><span class='op'>]</span><span class='op'>)</span> -</div><div class='img'><img src='add_err-3.png' alt='' width='700' height='433' /></div><div class='input'><span class='co'># }</span> - -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="co"># The kinetic model</span></span> +<span class="r-in"><span class="va">m_SFO_SFO</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"M1"</span><span class="op">)</span>,</span> +<span class="r-in"> M1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>, use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Generate a prediction for a specific set of parameters</span></span> +<span class="r-in"><span class="va">sampling_times</span> <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">1</span>, <span class="fl">3</span>, <span class="fl">7</span>, <span class="fl">14</span>, <span class="fl">28</span>, <span class="fl">60</span>, <span class="fl">90</span>, <span class="fl">120</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># This is the prediction used for the "Type 2 datasets" on the Piacenza poster</span></span> +<span class="r-in"><span class="co"># from 2015</span></span> +<span class="r-in"><span class="va">d_SFO_SFO</span> <span class="op"><-</span> <span class="fu"><a href="mkinpredict.html">mkinpredict</a></span><span class="op">(</span><span class="va">m_SFO_SFO</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_parent <span class="op">=</span> <span class="fl">0.1</span>, f_parent_to_M1 <span class="op">=</span> <span class="fl">0.5</span>,</span> +<span class="r-in"> k_M1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/Log.html" class="external-link">log</a></span><span class="op">(</span><span class="fl">2</span><span class="op">)</span><span class="op">/</span><span class="fl">1000</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span>, M1 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">sampling_times</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Add an error term with a constant (independent of the value) standard deviation</span></span> +<span class="r-in"><span class="co"># of 10, and generate three datasets</span></span> +<span class="r-in"><span class="va">d_SFO_SFO_err</span> <span class="op"><-</span> <span class="fu">add_err</span><span class="op">(</span><span class="va">d_SFO_SFO</span>, <span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fl">10</span>, n <span class="op">=</span> <span class="fl">3</span>, seed <span class="op">=</span> <span class="fl">123456789</span> <span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Name the datasets for nicer plotting</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">d_SFO_SFO_err</span><span class="op">)</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste</a></span><span class="op">(</span><span class="st">"Dataset"</span>, <span class="fl">1</span><span class="op">:</span><span class="fl">3</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Name the model in the list of models (with only one member in this case) for</span></span> +<span class="r-in"><span class="co"># nicer plotting later on. Be quiet and use only one core not to offend CRAN</span></span> +<span class="r-in"><span class="co"># checks</span></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="va">f_SFO_SFO</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="st">"SFO-SFO"</span> <span class="op">=</span> <span class="va">m_SFO_SFO</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">d_SFO_SFO_err</span>, cores <span class="op">=</span> <span class="fl">1</span>,</span> +<span class="r-in"> quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_SFO_SFO</span><span class="op">)</span></span> +<span class="r-plt img"><img src="add_err-1.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># We would like to inspect the fit for dataset 3 more closely</span></span> +<span class="r-in"><span class="co"># Using double brackets makes the returned object an mkinfit object</span></span> +<span class="r-in"><span class="co"># instead of a list of mkinfit objects, so plot.mkinfit is used</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_SFO_SFO</span><span class="op">[[</span><span class="fl">3</span><span class="op">]</span><span class="op">]</span>, show_residuals <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-plt img"><img src="add_err-2.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># If we use single brackets, we should give two indices (model and dataset),</span></span> +<span class="r-in"><span class="co"># and plot.mmkin is used</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_SFO_SFO</span><span class="op">[</span><span class="fl">1</span>, <span class="fl">3</span><span class="op">]</span><span class="op">)</span></span> +<span class="r-plt img"><img src="add_err-3.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="co"># }</span></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/aw.html b/docs/reference/aw.html index 6399b839..534cdf80 100644 --- a/docs/reference/aw.html +++ b/docs/reference/aw.html @@ -1,69 +1,14 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Calculate Akaike weights for model averaging — aw • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Calculate Akaike weights for model averaging — aw" /> -<meta property="og:description" content="Akaike weights are calculated based on the relative +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Calculate Akaike weights for model averaging — aw • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Calculate Akaike weights for model averaging — aw"><meta property="og:description" content="Akaike weights are calculated based on the relative expected Kullback-Leibler information as specified -by Burnham and Anderson (2004)." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +by Burnham and Anderson (2004)."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -74,13 +19,12 @@ by Burnham and Anderson (2004)." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -89,8 +33,7 @@ by Burnham and Anderson (2004)." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -100,6 +43,9 @@ by Burnham and Anderson (2004)." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -114,34 +60,27 @@ by Burnham and Anderson (2004)." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Calculate Akaike weights for model averaging</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/aw.R'><code>R/aw.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/aw.R" class="external-link"><code>R/aw.R</code></a></small> <div class="hidden name"><code>aw.Rd</code></div> </div> @@ -151,76 +90,76 @@ expected Kullback-Leibler information as specified by Burnham and Anderson (2004).</p> </div> - <pre class="usage"><span class='fu'>aw</span><span class='op'>(</span><span class='va'>object</span>, <span class='va'>...</span><span class='op'>)</span> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">aw</span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span><span class="op">)</span> -<span class='co'># S3 method for mkinfit</span> -<span class='fu'>aw</span><span class='op'>(</span><span class='va'>object</span>, <span class='va'>...</span><span class='op'>)</span> +<span class="co"># S3 method for mkinfit</span> +<span class="fu">aw</span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span><span class="op">)</span> -<span class='co'># S3 method for mmkin</span> -<span class='fu'>aw</span><span class='op'>(</span><span class='va'>object</span>, <span class='va'>...</span><span class='op'>)</span></pre> +<span class="co"># S3 method for mmkin</span> +<span class="fu">aw</span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>An <a href='mmkin.html'>mmkin</a> column object, containing two or more -<a href='mkinfit.html'>mkinfit</a> models that have been fitted to the same data, + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>An <a href="mmkin.html">mmkin</a> column object, containing two or more +<a href="mkinfit.html">mkinfit</a> models that have been fitted to the same data, or an mkinfit object. In the latter case, further mkinfit objects fitted to the same data should be specified -as dots arguments.</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Not used in the method for <a href='mmkin.html'>mmkin</a> column objects, -further <a href='mkinfit.html'>mkinfit</a> objects in the method for mkinfit objects.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - +as dots arguments.</p></dd> +<dt>...</dt> +<dd><p>Not used in the method for <a href="mmkin.html">mmkin</a> column objects, +further <a href="mkinfit.html">mkinfit</a> objects in the method for mkinfit objects.</p></dd> +</dl></div> + <div id="references"> + <h2>References</h2> <p>Burnham KP and Anderson DR (2004) Multimodel Inference: Understanding AIC and BIC in Model Selection. <em>Sociological Methods & Research</em> <strong>33</strong>(2) 261-304</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='co'># \dontrun{</span> -<span class='va'>f_sfo</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='va'>FOCUS_2006_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='va'>f_dfop</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"DFOP"</span>, <span class='va'>FOCUS_2006_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='va'>aw_sfo_dfop</span> <span class='op'><-</span> <span class='fu'>aw</span><span class='op'>(</span><span class='va'>f_sfo</span>, <span class='va'>f_dfop</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/sum.html'>sum</a></span><span class='op'>(</span><span class='va'>aw_sfo_dfop</span><span class='op'>)</span> -</div><div class='output co'>#> [1] 1</div><div class='input'><span class='va'>aw_sfo_dfop</span> <span class='co'># SFO gets more weight as it has less parameters and a similar fit</span> -</div><div class='output co'>#> [1] 0.5970258 0.4029742</div><div class='input'><span class='va'>f</span> <span class='op'><-</span> <span class='fu'><a href='mmkin.html'>mmkin</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"FOMC"</span>, <span class='st'>"DFOP"</span><span class='op'>)</span>, <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span><span class='st'>"FOCUS D"</span> <span class='op'>=</span> <span class='va'>FOCUS_2006_D</span><span class='op'>)</span>, cores <span class='op'>=</span> <span class='fl'>1</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'>aw</span><span class='op'>(</span><span class='va'>f</span><span class='op'>)</span> -</div><div class='output co'>#> [1] 0.4808722 0.1945539 0.3245740</div><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/sum.html'>sum</a></span><span class='op'>(</span><span class='fu'>aw</span><span class='op'>(</span><span class='va'>f</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> [1] 1</div><div class='input'><span class='fu'>aw</span><span class='op'>(</span><span class='va'>f</span><span class='op'>[</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"DFOP"</span><span class='op'>)</span><span class='op'>]</span><span class='op'>)</span> -</div><div class='output co'>#> [1] 0.5970258 0.4029742</div><div class='input'><span class='co'># }</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="va">f_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="va">FOCUS_2006_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_dfop</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="va">FOCUS_2006_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">aw_sfo_dfop</span> <span class="op"><-</span> <span class="fu">aw</span><span class="op">(</span><span class="va">f_sfo</span>, <span class="va">f_dfop</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/sum.html" class="external-link">sum</a></span><span class="op">(</span><span class="va">aw_sfo_dfop</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 1</span> +<span class="r-in"><span class="va">aw_sfo_dfop</span> <span class="co"># SFO gets more weight as it has less parameters and a similar fit</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 0.5970258 0.4029742</span> +<span class="r-in"><span class="va">f</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"FOMC"</span>, <span class="st">"DFOP"</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="st">"FOCUS D"</span> <span class="op">=</span> <span class="va">FOCUS_2006_D</span><span class="op">)</span>, cores <span class="op">=</span> <span class="fl">1</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu">aw</span><span class="op">(</span><span class="va">f</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 0.4808722 0.1945539 0.3245740</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/sum.html" class="external-link">sum</a></span><span class="op">(</span><span class="fu">aw</span><span class="op">(</span><span class="va">f</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 1</span> +<span class="r-in"><span class="fu">aw</span><span class="op">(</span><span class="va">f</span><span class="op">[</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"DFOP"</span><span class="op">)</span><span class="op">]</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 0.5970258 0.4029742</span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/confint.mkinfit.html b/docs/reference/confint.mkinfit.html index e81e0c7b..a57164cc 100644 --- a/docs/reference/confint.mkinfit.html +++ b/docs/reference/confint.mkinfit.html @@ -1,74 +1,19 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Confidence intervals for parameters of mkinfit objects — confint.mkinfit • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Confidence intervals for parameters of mkinfit objects — confint.mkinfit" /> -<meta property="og:description" content="The default method 'quadratic' is based on the quadratic approximation of +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Confidence intervals for parameters of mkinfit objects — confint.mkinfit • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Confidence intervals for parameters of mkinfit objects — confint.mkinfit"><meta property="og:description" content="The default method 'quadratic' is based on the quadratic approximation of the curvature of the likelihood function at the maximum likelihood parameter estimates. The alternative method 'profile' is based on the profile likelihood for each parameter. The 'profile' method uses two nested optimisations and can take a very long time, even if parallelized by specifying 'cores' on unixoid platforms. The speed of the method could likely be improved by using the -method of Venzon and Moolgavkar (1988)." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +method of Venzon and Moolgavkar (1988)."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -79,13 +24,12 @@ method of Venzon and Moolgavkar (1988)." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -94,8 +38,7 @@ method of Venzon and Moolgavkar (1988)." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -105,6 +48,9 @@ method of Venzon and Moolgavkar (1988)." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -119,34 +65,27 @@ method of Venzon and Moolgavkar (1988)." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Confidence intervals for parameters of mkinfit objects</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/confint.mkinfit.R'><code>R/confint.mkinfit.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/confint.mkinfit.R" class="external-link"><code>R/confint.mkinfit.R</code></a></small> <div class="hidden name"><code>confint.mkinfit.Rd</code></div> </div> @@ -161,279 +100,276 @@ platforms. The speed of the method could likely be improved by using the method of Venzon and Moolgavkar (1988).</p> </div> - <pre class="usage"><span class='co'># S3 method for mkinfit</span> -<span class='fu'><a href='https://rdrr.io/r/stats/confint.html'>confint</a></span><span class='op'>(</span> - <span class='va'>object</span>, - <span class='va'>parm</span>, - level <span class='op'>=</span> <span class='fl'>0.95</span>, - alpha <span class='op'>=</span> <span class='fl'>1</span> <span class='op'>-</span> <span class='va'>level</span>, - <span class='va'>cutoff</span>, - method <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"quadratic"</span>, <span class='st'>"profile"</span><span class='op'>)</span>, - transformed <span class='op'>=</span> <span class='cn'>TRUE</span>, - backtransform <span class='op'>=</span> <span class='cn'>TRUE</span>, - cores <span class='op'>=</span> <span class='fu'>parallel</span><span class='fu'>::</span><span class='fu'><a href='https://rdrr.io/r/parallel/detectCores.html'>detectCores</a></span><span class='op'>(</span><span class='op'>)</span>, - rel_tol <span class='op'>=</span> <span class='fl'>0.01</span>, - quiet <span class='op'>=</span> <span class='cn'>FALSE</span>, - <span class='va'>...</span> -<span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for mkinfit</span> +<span class="fu"><a href="https://rdrr.io/r/stats/confint.html" class="external-link">confint</a></span><span class="op">(</span> + <span class="va">object</span>, + <span class="va">parm</span>, + level <span class="op">=</span> <span class="fl">0.95</span>, + alpha <span class="op">=</span> <span class="fl">1</span> <span class="op">-</span> <span class="va">level</span>, + <span class="va">cutoff</span>, + method <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"quadratic"</span>, <span class="st">"profile"</span><span class="op">)</span>, + transformed <span class="op">=</span> <span class="cn">TRUE</span>, + backtransform <span class="op">=</span> <span class="cn">TRUE</span>, + cores <span class="op">=</span> <span class="fu">parallel</span><span class="fu">::</span><span class="fu"><a href="https://rdrr.io/r/parallel/detectCores.html" class="external-link">detectCores</a></span><span class="op">(</span><span class="op">)</span>, + rel_tol <span class="op">=</span> <span class="fl">0.01</span>, + quiet <span class="op">=</span> <span class="cn">FALSE</span>, + <span class="va">...</span> +<span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>An <code><a href='mkinfit.html'>mkinfit</a></code> object</p></td> - </tr> - <tr> - <th>parm</th> - <td><p>A vector of names of the parameters which are to be given -confidence intervals. If missing, all parameters are considered.</p></td> - </tr> - <tr> - <th>level</th> - <td><p>The confidence level required</p></td> - </tr> - <tr> - <th>alpha</th> - <td><p>The allowed error probability, overrides 'level' if specified.</p></td> - </tr> - <tr> - <th>cutoff</th> - <td><p>Possibility to specify an alternative cutoff for the difference + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>An <code><a href="mkinfit.html">mkinfit</a></code> object</p></dd> +<dt>parm</dt> +<dd><p>A vector of names of the parameters which are to be given +confidence intervals. If missing, all parameters are considered.</p></dd> +<dt>level</dt> +<dd><p>The confidence level required</p></dd> +<dt>alpha</dt> +<dd><p>The allowed error probability, overrides 'level' if specified.</p></dd> +<dt>cutoff</dt> +<dd><p>Possibility to specify an alternative cutoff for the difference in the log-likelihoods at the confidence boundary. Specifying an explicit -cutoff value overrides arguments 'level' and 'alpha'</p></td> - </tr> - <tr> - <th>method</th> - <td><p>The 'quadratic' method approximates the likelihood function at +cutoff value overrides arguments 'level' and 'alpha'</p></dd> +<dt>method</dt> +<dd><p>The 'quadratic' method approximates the likelihood function at the optimised parameters using the second term of the Taylor expansion, using a second derivative (hessian) contained in the object. The 'profile' method searches the parameter space for the -cutoff of the confidence intervals by means of a likelihood ratio test.</p></td> - </tr> - <tr> - <th>transformed</th> - <td><p>If the quadratic approximation is used, should it be -applied to the likelihood based on the transformed parameters?</p></td> - </tr> - <tr> - <th>backtransform</th> - <td><p>If we approximate the likelihood in terms of the +cutoff of the confidence intervals by means of a likelihood ratio test.</p></dd> +<dt>transformed</dt> +<dd><p>If the quadratic approximation is used, should it be +applied to the likelihood based on the transformed parameters?</p></dd> +<dt>backtransform</dt> +<dd><p>If we approximate the likelihood in terms of the transformed parameters, should we backtransform the parameters with -their confidence intervals?</p></td> - </tr> - <tr> - <th>cores</th> - <td><p>The number of cores to be used for multicore processing. -On Windows machines, cores > 1 is currently not supported.</p></td> - </tr> - <tr> - <th>rel_tol</th> - <td><p>If the method is 'profile', what should be the accuracy +their confidence intervals?</p></dd> +<dt>cores</dt> +<dd><p>The number of cores to be used for multicore processing. +On Windows machines, cores > 1 is currently not supported.</p></dd> +<dt>rel_tol</dt> +<dd><p>If the method is 'profile', what should be the accuracy of the lower and upper bounds, relative to the estimate obtained from -the quadratic method?</p></td> - </tr> - <tr> - <th>quiet</th> - <td><p>Should we suppress the message "Profiling the likelihood"</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Not used</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - +the quadratic method?</p></dd> +<dt>quiet</dt> +<dd><p>Should we suppress the message "Profiling the likelihood"</p></dd> +<dt>...</dt> +<dd><p>Not used</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>A matrix with columns giving lower and upper confidence limits for each parameter.</p> - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - + </div> + <div id="references"> + <h2>References</h2> <p>Bates DM and Watts GW (1988) Nonlinear regression analysis & its applications</p> <p>Pawitan Y (2013) In all likelihood - Statistical modelling and inference using likelihood. Clarendon Press, Oxford.</p> <p>Venzon DJ and Moolgavkar SH (1988) A Method for Computing Profile-Likelihood Based Confidence Intervals, Applied Statistics, 37, 87–94.</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='va'>f</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='va'>FOCUS_2006_C</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/stats/confint.html'>confint</a></span><span class='op'>(</span><span class='va'>f</span>, method <span class='op'>=</span> <span class='st'>"quadratic"</span><span class='op'>)</span> -</div><div class='output co'>#> 2.5% 97.5% -#> parent_0 71.8242430 93.1600766 -#> k_parent 0.2109541 0.4440528 -#> sigma 1.9778868 7.3681380</div><div class='input'> -<span class='co'># \dontrun{</span> -<span class='fu'><a href='https://rdrr.io/r/stats/confint.html'>confint</a></span><span class='op'>(</span><span class='va'>f</span>, method <span class='op'>=</span> <span class='st'>"profile"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Profiling the likelihood</span></div><div class='output co'>#> 2.5% 97.5% -#> parent_0 73.0641834 92.1392181 -#> k_parent 0.2170293 0.4235348 -#> sigma 3.1307772 8.0628314</div><div class='input'> -<span class='co'># Set the number of cores for the profiling method for further examples</span> -<span class='kw'>if</span> <span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/identical.html'>identical</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/Sys.getenv.html'>Sys.getenv</a></span><span class='op'>(</span><span class='st'>"NOT_CRAN"</span><span class='op'>)</span>, <span class='st'>"true"</span><span class='op'>)</span><span class='op'>)</span> <span class='op'>{</span> - <span class='va'>n_cores</span> <span class='op'><-</span> <span class='fu'>parallel</span><span class='fu'>::</span><span class='fu'><a href='https://rdrr.io/r/parallel/detectCores.html'>detectCores</a></span><span class='op'>(</span><span class='op'>)</span> <span class='op'>-</span> <span class='fl'>1</span> -<span class='op'>}</span> <span class='kw'>else</span> <span class='op'>{</span> - <span class='va'>n_cores</span> <span class='op'><-</span> <span class='fl'>1</span> -<span class='op'>}</span> -<span class='kw'>if</span> <span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/Sys.getenv.html'>Sys.getenv</a></span><span class='op'>(</span><span class='st'>"TRAVIS"</span><span class='op'>)</span> <span class='op'>!=</span> <span class='st'>""</span><span class='op'>)</span> <span class='va'>n_cores</span> <span class='op'>=</span> <span class='fl'>1</span> -<span class='kw'>if</span> <span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/Sys.info.html'>Sys.info</a></span><span class='op'>(</span><span class='op'>)</span><span class='op'>[</span><span class='st'>"sysname"</span><span class='op'>]</span> <span class='op'>==</span> <span class='st'>"Windows"</span><span class='op'>)</span> <span class='va'>n_cores</span> <span class='op'>=</span> <span class='fl'>1</span> - -<span class='va'>SFO_SFO</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"m1"</span><span class='op'>)</span>, m1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, - use_of_ff <span class='op'>=</span> <span class='st'>"min"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='va'>SFO_SFO.ff</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"m1"</span><span class='op'>)</span>, m1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, - use_of_ff <span class='op'>=</span> <span class='st'>"max"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='va'>f_d_1</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='fu'><a href='https://rdrr.io/r/base/subset.html'>subset</a></span><span class='op'>(</span><span class='va'>FOCUS_2006_D</span>, <span class='va'>value</span> <span class='op'>!=</span> <span class='fl'>0</span><span class='op'>)</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/system.time.html'>system.time</a></span><span class='op'>(</span><span class='va'>ci_profile</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/confint.html'>confint</a></span><span class='op'>(</span><span class='va'>f_d_1</span>, method <span class='op'>=</span> <span class='st'>"profile"</span>, cores <span class='op'>=</span> <span class='fl'>1</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> user system elapsed -#> 3.871 0.000 3.871 </div><div class='input'><span class='co'># Using more cores does not save much time here, as parent_0 takes up most of the time</span> -<span class='co'># If we additionally exclude parent_0 (the confidence of which is often of</span> -<span class='co'># minor interest), we get a nice performance improvement if we use at least 4 cores</span> -<span class='fu'><a href='https://rdrr.io/r/base/system.time.html'>system.time</a></span><span class='op'>(</span><span class='va'>ci_profile_no_parent_0</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/confint.html'>confint</a></span><span class='op'>(</span><span class='va'>f_d_1</span>, method <span class='op'>=</span> <span class='st'>"profile"</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"k_parent_sink"</span>, <span class='st'>"k_parent_m1"</span>, <span class='st'>"k_m1_sink"</span>, <span class='st'>"sigma"</span><span class='op'>)</span>, cores <span class='op'>=</span> <span class='va'>n_cores</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Profiling the likelihood</span></div><div class='output co'>#> user system elapsed -#> 1.484 0.116 0.923 </div><div class='input'><span class='va'>ci_profile</span> -</div><div class='output co'>#> 2.5% 97.5% -#> parent_0 96.456003640 1.027703e+02 -#> k_parent_sink 0.040762501 5.549764e-02 -#> k_parent_m1 0.046786482 5.500879e-02 -#> k_m1_sink 0.003892605 6.702778e-03 -#> sigma 2.535612399 3.985263e+00</div><div class='input'><span class='va'>ci_quadratic_transformed</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/confint.html'>confint</a></span><span class='op'>(</span><span class='va'>f_d_1</span>, method <span class='op'>=</span> <span class='st'>"quadratic"</span><span class='op'>)</span> -<span class='va'>ci_quadratic_transformed</span> -</div><div class='output co'>#> 2.5% 97.5% -#> parent_0 96.403841640 1.027931e+02 -#> k_parent_sink 0.041033378 5.596269e-02 -#> k_parent_m1 0.046777902 5.511931e-02 -#> k_m1_sink 0.004012217 6.897547e-03 -#> sigma 2.396089689 3.854918e+00</div><div class='input'><span class='va'>ci_quadratic_untransformed</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/confint.html'>confint</a></span><span class='op'>(</span><span class='va'>f_d_1</span>, method <span class='op'>=</span> <span class='st'>"quadratic"</span>, transformed <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span> -<span class='va'>ci_quadratic_untransformed</span> -</div><div class='output co'>#> 2.5% 97.5% -#> parent_0 96.403841645 102.79312449 -#> k_parent_sink 0.040485331 0.05535491 -#> k_parent_m1 0.046611582 0.05494364 -#> k_m1_sink 0.003835483 0.00668582 -#> sigma 2.396089689 3.85491806</div><div class='input'><span class='co'># Against the expectation based on Bates and Watts (1988), the confidence</span> -<span class='co'># intervals based on the internal parameter transformation are less</span> -<span class='co'># congruent with the likelihood based intervals. Note the superiority of the</span> -<span class='co'># interval based on the untransformed fit for k_m1_sink</span> -<span class='va'>rel_diffs_transformed</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/MathFun.html'>abs</a></span><span class='op'>(</span><span class='op'>(</span><span class='va'>ci_quadratic_transformed</span> <span class='op'>-</span> <span class='va'>ci_profile</span><span class='op'>)</span><span class='op'>/</span><span class='va'>ci_profile</span><span class='op'>)</span> -<span class='va'>rel_diffs_untransformed</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/MathFun.html'>abs</a></span><span class='op'>(</span><span class='op'>(</span><span class='va'>ci_quadratic_untransformed</span> <span class='op'>-</span> <span class='va'>ci_profile</span><span class='op'>)</span><span class='op'>/</span><span class='va'>ci_profile</span><span class='op'>)</span> -<span class='va'>rel_diffs_transformed</span> <span class='op'><</span> <span class='va'>rel_diffs_untransformed</span> -</div><div class='output co'>#> 2.5% 97.5% -#> parent_0 FALSE FALSE -#> k_parent_sink TRUE FALSE -#> k_parent_m1 TRUE FALSE -#> k_m1_sink FALSE FALSE -#> sigma FALSE FALSE</div><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/Round.html'>signif</a></span><span class='op'>(</span><span class='va'>rel_diffs_transformed</span>, <span class='fl'>3</span><span class='op'>)</span> -</div><div class='output co'>#> 2.5% 97.5% -#> parent_0 0.000541 0.000222 -#> k_parent_sink 0.006650 0.008380 -#> k_parent_m1 0.000183 0.002010 -#> k_m1_sink 0.030700 0.029100 -#> sigma 0.055000 0.032700</div><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/Round.html'>signif</a></span><span class='op'>(</span><span class='va'>rel_diffs_untransformed</span>, <span class='fl'>3</span><span class='op'>)</span> -</div><div class='output co'>#> 2.5% 97.5% -#> parent_0 0.000541 0.000222 -#> k_parent_sink 0.006800 0.002570 -#> k_parent_m1 0.003740 0.001180 -#> k_m1_sink 0.014700 0.002530 -#> sigma 0.055000 0.032700</div><div class='input'> - -<span class='co'># Investigate a case with formation fractions</span> -<span class='va'>f_d_2</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO.ff</span>, <span class='fu'><a href='https://rdrr.io/r/base/subset.html'>subset</a></span><span class='op'>(</span><span class='va'>FOCUS_2006_D</span>, <span class='va'>value</span> <span class='op'>!=</span> <span class='fl'>0</span><span class='op'>)</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='va'>ci_profile_ff</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/confint.html'>confint</a></span><span class='op'>(</span><span class='va'>f_d_2</span>, method <span class='op'>=</span> <span class='st'>"profile"</span>, cores <span class='op'>=</span> <span class='va'>n_cores</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Profiling the likelihood</span></div><div class='input'><span class='va'>ci_profile_ff</span> -</div><div class='output co'>#> 2.5% 97.5% -#> parent_0 96.456003640 1.027703e+02 -#> k_parent 0.090911032 1.071578e-01 -#> k_m1 0.003892606 6.702775e-03 -#> f_parent_to_m1 0.471328495 5.611550e-01 -#> sigma 2.535612399 3.985263e+00</div><div class='input'><span class='va'>ci_quadratic_transformed_ff</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/confint.html'>confint</a></span><span class='op'>(</span><span class='va'>f_d_2</span>, method <span class='op'>=</span> <span class='st'>"quadratic"</span><span class='op'>)</span> -<span class='va'>ci_quadratic_transformed_ff</span> -</div><div class='output co'>#> 2.5% 97.5% -#> parent_0 96.403833578 102.79311649 -#> k_parent 0.090823771 0.10725430 -#> k_m1 0.004012219 0.00689755 -#> f_parent_to_m1 0.469118824 0.55959615 -#> sigma 2.396089689 3.85491806</div><div class='input'><span class='va'>ci_quadratic_untransformed_ff</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/confint.html'>confint</a></span><span class='op'>(</span><span class='va'>f_d_2</span>, method <span class='op'>=</span> <span class='st'>"quadratic"</span>, transformed <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span> -<span class='va'>ci_quadratic_untransformed_ff</span> -</div><div class='output co'>#> 2.5% 97.5% -#> parent_0 96.403833583 1.027931e+02 -#> k_parent 0.090491913 1.069035e-01 -#> k_m1 0.003835485 6.685823e-03 -#> f_parent_to_m1 0.469113477 5.598387e-01 -#> sigma 2.396089689 3.854918e+00</div><div class='input'><span class='va'>rel_diffs_transformed_ff</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/MathFun.html'>abs</a></span><span class='op'>(</span><span class='op'>(</span><span class='va'>ci_quadratic_transformed_ff</span> <span class='op'>-</span> <span class='va'>ci_profile_ff</span><span class='op'>)</span><span class='op'>/</span><span class='va'>ci_profile_ff</span><span class='op'>)</span> -<span class='va'>rel_diffs_untransformed_ff</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/MathFun.html'>abs</a></span><span class='op'>(</span><span class='op'>(</span><span class='va'>ci_quadratic_untransformed_ff</span> <span class='op'>-</span> <span class='va'>ci_profile_ff</span><span class='op'>)</span><span class='op'>/</span><span class='va'>ci_profile_ff</span><span class='op'>)</span> -<span class='co'># While the confidence interval for the parent rate constant is closer to</span> -<span class='co'># the profile based interval when using the internal parameter</span> -<span class='co'># transformation, the interval for the metabolite rate constant is 'better</span> -<span class='co'># without internal parameter transformation.</span> -<span class='va'>rel_diffs_transformed_ff</span> <span class='op'><</span> <span class='va'>rel_diffs_untransformed_ff</span> -</div><div class='output co'>#> 2.5% 97.5% -#> parent_0 FALSE FALSE -#> k_parent TRUE TRUE -#> k_m1 FALSE FALSE -#> f_parent_to_m1 TRUE FALSE -#> sigma TRUE FALSE</div><div class='input'><span class='va'>rel_diffs_transformed_ff</span> -</div><div class='output co'>#> 2.5% 97.5% -#> parent_0 0.0005408690 0.0002217233 -#> k_parent 0.0009598532 0.0009001864 -#> k_m1 0.0307283041 0.0290588361 -#> f_parent_to_m1 0.0046881769 0.0027780063 -#> sigma 0.0550252516 0.0327066836</div><div class='input'><span class='va'>rel_diffs_untransformed_ff</span> -</div><div class='output co'>#> 2.5% 97.5% -#> parent_0 0.0005408689 0.0002217232 -#> k_parent 0.0046102156 0.0023732281 -#> k_m1 0.0146740690 0.0025291820 -#> f_parent_to_m1 0.0046995211 0.0023457712 -#> sigma 0.0550252516 0.0327066836</div><div class='input'> -<span class='co'># The profiling for the following fit does not finish in a reasonable time,</span> -<span class='co'># therefore we use the quadratic approximation</span> -<span class='va'>m_synth_DFOP_par</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"DFOP"</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"M1"</span>, <span class='st'>"M2"</span><span class='op'>)</span><span class='op'>)</span>, - M1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, - M2 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, - use_of_ff <span class='op'>=</span> <span class='st'>"max"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='va'>DFOP_par_c</span> <span class='op'><-</span> <span class='va'>synthetic_data_for_UBA_2014</span><span class='op'>[[</span><span class='fl'>12</span><span class='op'>]</span><span class='op'>]</span><span class='op'>$</span><span class='va'>data</span> -<span class='va'>f_tc_2</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>m_synth_DFOP_par</span>, <span class='va'>DFOP_par_c</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span>, - error_model_algorithm <span class='op'>=</span> <span class='st'>"direct"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/stats/confint.html'>confint</a></span><span class='op'>(</span><span class='va'>f_tc_2</span>, method <span class='op'>=</span> <span class='st'>"quadratic"</span><span class='op'>)</span> -</div><div class='output co'>#> 2.5% 97.5% -#> parent_0 94.596039609 106.19954892 -#> k_M1 0.037605368 0.04490762 -#> k_M2 0.008568731 0.01087676 -#> f_parent_to_M1 0.021462489 0.62023882 -#> f_parent_to_M2 0.015165617 0.37975348 -#> k1 0.273897348 0.33388101 -#> k2 0.018614554 0.02250378 -#> g 0.671943411 0.73583305 -#> sigma_low 0.251283495 0.83992077 -#> rsd_high 0.040411024 0.07662008</div><div class='input'><span class='fu'><a href='https://rdrr.io/r/stats/confint.html'>confint</a></span><span class='op'>(</span><span class='va'>f_tc_2</span>, <span class='st'>"parent_0"</span>, method <span class='op'>=</span> <span class='st'>"quadratic"</span><span class='op'>)</span> -</div><div class='output co'>#> 2.5% 97.5% -#> parent_0 94.59604 106.1995</div><div class='input'><span class='co'># }</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="va">f</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="va">FOCUS_2006_C</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/stats/confint.html" class="external-link">confint</a></span><span class="op">(</span><span class="va">f</span>, method <span class="op">=</span> <span class="st">"quadratic"</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> 2.5% 97.5%</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 71.8242430 93.1600766</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.2109541 0.4440528</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 1.9778868 7.3681380</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/stats/confint.html" class="external-link">confint</a></span><span class="op">(</span><span class="va">f</span>, method <span class="op">=</span> <span class="st">"profile"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Profiling the likelihood</span> +<span class="r-out co"><span class="r-pr">#></span> 2.5% 97.5%</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 73.0641834 92.1392181</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.2170293 0.4235348</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 3.1307772 8.0628314</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Set the number of cores for the profiling method for further examples</span></span> +<span class="r-in"><span class="kw">if</span> <span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/identical.html" class="external-link">identical</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/Sys.getenv.html" class="external-link">Sys.getenv</a></span><span class="op">(</span><span class="st">"NOT_CRAN"</span><span class="op">)</span>, <span class="st">"true"</span><span class="op">)</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="va">n_cores</span> <span class="op"><-</span> <span class="fu">parallel</span><span class="fu">::</span><span class="fu"><a href="https://rdrr.io/r/parallel/detectCores.html" class="external-link">detectCores</a></span><span class="op">(</span><span class="op">)</span> <span class="op">-</span> <span class="fl">1</span></span> +<span class="r-in"><span class="op">}</span> <span class="kw">else</span> <span class="op">{</span></span> +<span class="r-in"> <span class="va">n_cores</span> <span class="op"><-</span> <span class="fl">1</span></span> +<span class="r-in"><span class="op">}</span></span> +<span class="r-in"><span class="kw">if</span> <span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/Sys.getenv.html" class="external-link">Sys.getenv</a></span><span class="op">(</span><span class="st">"TRAVIS"</span><span class="op">)</span> <span class="op">!=</span> <span class="st">""</span><span class="op">)</span> <span class="va">n_cores</span> <span class="op">=</span> <span class="fl">1</span></span> +<span class="r-in"><span class="kw">if</span> <span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/Sys.info.html" class="external-link">Sys.info</a></span><span class="op">(</span><span class="op">)</span><span class="op">[</span><span class="st">"sysname"</span><span class="op">]</span> <span class="op">==</span> <span class="st">"Windows"</span><span class="op">)</span> <span class="va">n_cores</span> <span class="op">=</span> <span class="fl">1</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">SFO_SFO</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"m1"</span><span class="op">)</span>, m1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> use_of_ff <span class="op">=</span> <span class="st">"min"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">SFO_SFO.ff</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"m1"</span><span class="op">)</span>, m1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> use_of_ff <span class="op">=</span> <span class="st">"max"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_d_1</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="fu"><a href="https://rdrr.io/r/base/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">FOCUS_2006_D</span>, <span class="va">value</span> <span class="op">!=</span> <span class="fl">0</span><span class="op">)</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/system.time.html" class="external-link">system.time</a></span><span class="op">(</span><span class="va">ci_profile</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/confint.html" class="external-link">confint</a></span><span class="op">(</span><span class="va">f_d_1</span>, method <span class="op">=</span> <span class="st">"profile"</span>, cores <span class="op">=</span> <span class="fl">1</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> user system elapsed </span> +<span class="r-out co"><span class="r-pr">#></span> 3.933 0.000 3.934 </span> +<span class="r-in"><span class="co"># Using more cores does not save much time here, as parent_0 takes up most of the time</span></span> +<span class="r-in"><span class="co"># If we additionally exclude parent_0 (the confidence of which is often of</span></span> +<span class="r-in"><span class="co"># minor interest), we get a nice performance improvement if we use at least 4 cores</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/system.time.html" class="external-link">system.time</a></span><span class="op">(</span><span class="va">ci_profile_no_parent_0</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/confint.html" class="external-link">confint</a></span><span class="op">(</span><span class="va">f_d_1</span>, method <span class="op">=</span> <span class="st">"profile"</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"k_parent_sink"</span>, <span class="st">"k_parent_m1"</span>, <span class="st">"k_m1_sink"</span>, <span class="st">"sigma"</span><span class="op">)</span>, cores <span class="op">=</span> <span class="va">n_cores</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Profiling the likelihood</span> +<span class="r-out co"><span class="r-pr">#></span> user system elapsed </span> +<span class="r-out co"><span class="r-pr">#></span> 1.496 0.172 0.968 </span> +<span class="r-in"><span class="va">ci_profile</span></span> +<span class="r-out co"><span class="r-pr">#></span> 2.5% 97.5%</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 96.456003640 1.027703e+02</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_sink 0.040762501 5.549764e-02</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_m1 0.046786482 5.500879e-02</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1_sink 0.003892605 6.702778e-03</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 2.535612399 3.985263e+00</span> +<span class="r-in"><span class="va">ci_quadratic_transformed</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/confint.html" class="external-link">confint</a></span><span class="op">(</span><span class="va">f_d_1</span>, method <span class="op">=</span> <span class="st">"quadratic"</span><span class="op">)</span></span> +<span class="r-in"><span class="va">ci_quadratic_transformed</span></span> +<span class="r-out co"><span class="r-pr">#></span> 2.5% 97.5%</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 96.403841640 1.027931e+02</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_sink 0.041033378 5.596269e-02</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_m1 0.046777902 5.511931e-02</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1_sink 0.004012217 6.897547e-03</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 2.396089689 3.854918e+00</span> +<span class="r-in"><span class="va">ci_quadratic_untransformed</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/confint.html" class="external-link">confint</a></span><span class="op">(</span><span class="va">f_d_1</span>, method <span class="op">=</span> <span class="st">"quadratic"</span>, transformed <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">ci_quadratic_untransformed</span></span> +<span class="r-out co"><span class="r-pr">#></span> 2.5% 97.5%</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 96.403841645 102.79312449</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_sink 0.040485331 0.05535491</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_m1 0.046611582 0.05494364</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1_sink 0.003835483 0.00668582</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 2.396089689 3.85491806</span> +<span class="r-in"><span class="co"># Against the expectation based on Bates and Watts (1988), the confidence</span></span> +<span class="r-in"><span class="co"># intervals based on the internal parameter transformation are less</span></span> +<span class="r-in"><span class="co"># congruent with the likelihood based intervals. Note the superiority of the</span></span> +<span class="r-in"><span class="co"># interval based on the untransformed fit for k_m1_sink</span></span> +<span class="r-in"><span class="va">rel_diffs_transformed</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/MathFun.html" class="external-link">abs</a></span><span class="op">(</span><span class="op">(</span><span class="va">ci_quadratic_transformed</span> <span class="op">-</span> <span class="va">ci_profile</span><span class="op">)</span><span class="op">/</span><span class="va">ci_profile</span><span class="op">)</span></span> +<span class="r-in"><span class="va">rel_diffs_untransformed</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/MathFun.html" class="external-link">abs</a></span><span class="op">(</span><span class="op">(</span><span class="va">ci_quadratic_untransformed</span> <span class="op">-</span> <span class="va">ci_profile</span><span class="op">)</span><span class="op">/</span><span class="va">ci_profile</span><span class="op">)</span></span> +<span class="r-in"><span class="va">rel_diffs_transformed</span> <span class="op"><</span> <span class="va">rel_diffs_untransformed</span></span> +<span class="r-out co"><span class="r-pr">#></span> 2.5% 97.5%</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 FALSE FALSE</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_sink TRUE FALSE</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_m1 TRUE FALSE</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1_sink FALSE FALSE</span> +<span class="r-out co"><span class="r-pr">#></span> sigma FALSE FALSE</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/Round.html" class="external-link">signif</a></span><span class="op">(</span><span class="va">rel_diffs_transformed</span>, <span class="fl">3</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> 2.5% 97.5%</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 0.000541 0.000222</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_sink 0.006650 0.008380</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_m1 0.000183 0.002010</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1_sink 0.030700 0.029100</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 0.055000 0.032700</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/Round.html" class="external-link">signif</a></span><span class="op">(</span><span class="va">rel_diffs_untransformed</span>, <span class="fl">3</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> 2.5% 97.5%</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 0.000541 0.000222</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_sink 0.006800 0.002570</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_m1 0.003740 0.001180</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1_sink 0.014700 0.002530</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 0.055000 0.032700</span> +<span class="r-in"></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Investigate a case with formation fractions</span></span> +<span class="r-in"><span class="va">f_d_2</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO.ff</span>, <span class="fu"><a href="https://rdrr.io/r/base/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">FOCUS_2006_D</span>, <span class="va">value</span> <span class="op">!=</span> <span class="fl">0</span><span class="op">)</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">ci_profile_ff</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/confint.html" class="external-link">confint</a></span><span class="op">(</span><span class="va">f_d_2</span>, method <span class="op">=</span> <span class="st">"profile"</span>, cores <span class="op">=</span> <span class="va">n_cores</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Profiling the likelihood</span> +<span class="r-in"><span class="va">ci_profile_ff</span></span> +<span class="r-out co"><span class="r-pr">#></span> 2.5% 97.5%</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 96.456003640 1.027703e+02</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.090911032 1.071578e-01</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1 0.003892606 6.702775e-03</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_m1 0.471328495 5.611550e-01</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 2.535612399 3.985263e+00</span> +<span class="r-in"><span class="va">ci_quadratic_transformed_ff</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/confint.html" class="external-link">confint</a></span><span class="op">(</span><span class="va">f_d_2</span>, method <span class="op">=</span> <span class="st">"quadratic"</span><span class="op">)</span></span> +<span class="r-in"><span class="va">ci_quadratic_transformed_ff</span></span> +<span class="r-out co"><span class="r-pr">#></span> 2.5% 97.5%</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 96.403833578 102.79311649</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.090823771 0.10725430</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1 0.004012219 0.00689755</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_m1 0.469118824 0.55959615</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 2.396089689 3.85491806</span> +<span class="r-in"><span class="va">ci_quadratic_untransformed_ff</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/confint.html" class="external-link">confint</a></span><span class="op">(</span><span class="va">f_d_2</span>, method <span class="op">=</span> <span class="st">"quadratic"</span>, transformed <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">ci_quadratic_untransformed_ff</span></span> +<span class="r-out co"><span class="r-pr">#></span> 2.5% 97.5%</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 96.403833583 1.027931e+02</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.090491913 1.069035e-01</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1 0.003835485 6.685823e-03</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_m1 0.469113477 5.598387e-01</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 2.396089689 3.854918e+00</span> +<span class="r-in"><span class="va">rel_diffs_transformed_ff</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/MathFun.html" class="external-link">abs</a></span><span class="op">(</span><span class="op">(</span><span class="va">ci_quadratic_transformed_ff</span> <span class="op">-</span> <span class="va">ci_profile_ff</span><span class="op">)</span><span class="op">/</span><span class="va">ci_profile_ff</span><span class="op">)</span></span> +<span class="r-in"><span class="va">rel_diffs_untransformed_ff</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/MathFun.html" class="external-link">abs</a></span><span class="op">(</span><span class="op">(</span><span class="va">ci_quadratic_untransformed_ff</span> <span class="op">-</span> <span class="va">ci_profile_ff</span><span class="op">)</span><span class="op">/</span><span class="va">ci_profile_ff</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># While the confidence interval for the parent rate constant is closer to</span></span> +<span class="r-in"><span class="co"># the profile based interval when using the internal parameter</span></span> +<span class="r-in"><span class="co"># transformation, the interval for the metabolite rate constant is 'better</span></span> +<span class="r-in"><span class="co"># without internal parameter transformation.</span></span> +<span class="r-in"><span class="va">rel_diffs_transformed_ff</span> <span class="op"><</span> <span class="va">rel_diffs_untransformed_ff</span></span> +<span class="r-out co"><span class="r-pr">#></span> 2.5% 97.5%</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 FALSE FALSE</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent TRUE TRUE</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1 FALSE FALSE</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_m1 TRUE FALSE</span> +<span class="r-out co"><span class="r-pr">#></span> sigma TRUE FALSE</span> +<span class="r-in"><span class="va">rel_diffs_transformed_ff</span></span> +<span class="r-out co"><span class="r-pr">#></span> 2.5% 97.5%</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 0.0005408690 0.0002217233</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.0009598532 0.0009001864</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1 0.0307283041 0.0290588361</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_m1 0.0046881769 0.0027780063</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 0.0550252516 0.0327066836</span> +<span class="r-in"><span class="va">rel_diffs_untransformed_ff</span></span> +<span class="r-out co"><span class="r-pr">#></span> 2.5% 97.5%</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 0.0005408689 0.0002217232</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.0046102156 0.0023732281</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1 0.0146740690 0.0025291820</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_m1 0.0046995211 0.0023457712</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 0.0550252516 0.0327066836</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># The profiling for the following fit does not finish in a reasonable time,</span></span> +<span class="r-in"><span class="co"># therefore we use the quadratic approximation</span></span> +<span class="r-in"><span class="va">m_synth_DFOP_par</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"M1"</span>, <span class="st">"M2"</span><span class="op">)</span><span class="op">)</span>,</span> +<span class="r-in"> M1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> M2 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> use_of_ff <span class="op">=</span> <span class="st">"max"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">DFOP_par_c</span> <span class="op"><-</span> <span class="va">synthetic_data_for_UBA_2014</span><span class="op">[[</span><span class="fl">12</span><span class="op">]</span><span class="op">]</span><span class="op">$</span><span class="va">data</span></span> +<span class="r-in"><span class="va">f_tc_2</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">m_synth_DFOP_par</span>, <span class="va">DFOP_par_c</span>, error_model <span class="op">=</span> <span class="st">"tc"</span>,</span> +<span class="r-in"> error_model_algorithm <span class="op">=</span> <span class="st">"direct"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/stats/confint.html" class="external-link">confint</a></span><span class="op">(</span><span class="va">f_tc_2</span>, method <span class="op">=</span> <span class="st">"quadratic"</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> 2.5% 97.5%</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 94.596039609 106.19954892</span> +<span class="r-out co"><span class="r-pr">#></span> k_M1 0.037605368 0.04490762</span> +<span class="r-out co"><span class="r-pr">#></span> k_M2 0.008568731 0.01087676</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_M1 0.021462489 0.62023882</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_M2 0.015165617 0.37975348</span> +<span class="r-out co"><span class="r-pr">#></span> k1 0.273897348 0.33388101</span> +<span class="r-out co"><span class="r-pr">#></span> k2 0.018614554 0.02250378</span> +<span class="r-out co"><span class="r-pr">#></span> g 0.671943411 0.73583305</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low 0.251283495 0.83992077</span> +<span class="r-out co"><span class="r-pr">#></span> rsd_high 0.040411024 0.07662008</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/stats/confint.html" class="external-link">confint</a></span><span class="op">(</span><span class="va">f_tc_2</span>, <span class="st">"parent_0"</span>, method <span class="op">=</span> <span class="st">"quadratic"</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> 2.5% 97.5%</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 94.59604 106.1995</span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/create_deg_func.html b/docs/reference/create_deg_func.html index 82583f1a..ca57addf 100644 --- a/docs/reference/create_deg_func.html +++ b/docs/reference/create_deg_func.html @@ -1,67 +1,12 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Create degradation functions for known analytical solutions — create_deg_func • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Create degradation functions for known analytical solutions — create_deg_func" /> -<meta property="og:description" content="Create degradation functions for known analytical solutions" /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Create degradation functions for known analytical solutions — create_deg_func • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Create degradation functions for known analytical solutions — create_deg_func"><meta property="og:description" content="Create degradation functions for known analytical solutions"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -72,13 +17,12 @@ </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -87,8 +31,7 @@ <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -98,6 +41,9 @@ <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -112,34 +58,27 @@ <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Create degradation functions for known analytical solutions</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/create_deg_func.R'><code>R/create_deg_func.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/create_deg_func.R" class="external-link"><code>R/create_deg_func.R</code></a></small> <div class="hidden name"><code>create_deg_func.Rd</code></div> </div> @@ -147,83 +86,83 @@ <p>Create degradation functions for known analytical solutions</p> </div> - <pre class="usage"><span class='fu'>create_deg_func</span><span class='op'>(</span><span class='va'>spec</span>, use_of_ff <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"min"</span>, <span class='st'>"max"</span><span class='op'>)</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>spec</th> - <td><p>List of model specifications as contained in mkinmod objects</p></td> - </tr> - <tr> - <th>use_of_ff</th> - <td><p>Minimum or maximum use of formation fractions</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">create_deg_func</span><span class="op">(</span><span class="va">spec</span>, use_of_ff <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"min"</span>, <span class="st">"max"</span><span class="op">)</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>spec</dt> +<dd><p>List of model specifications as contained in mkinmod objects</p></dd> +<dt>use_of_ff</dt> +<dd><p>Minimum or maximum use of formation fractions</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>Degradation function to be attached to mkinmod objects</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='va'>SFO_SFO</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"m1"</span><span class='op'>)</span>, - m1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'><span class='va'>FOCUS_D</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/subset.html'>subset</a></span><span class='op'>(</span><span class='va'>FOCUS_2006_D</span>, <span class='va'>value</span> <span class='op'>!=</span> <span class='fl'>0</span><span class='op'>)</span> <span class='co'># to avoid warnings</span> -<span class='va'>fit_1</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_D</span>, solution_type <span class='op'>=</span> <span class='st'>"analytical"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='va'>fit_2</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_D</span>, solution_type <span class='op'>=</span> <span class='st'>"deSolve"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='co'># \dontrun{</span> -<span class='kw'>if</span> <span class='op'>(</span><span class='kw'><a href='https://rdrr.io/r/base/library.html'>require</a></span><span class='op'>(</span><span class='va'><a href='http://rbenchmark.googlecode.com'>rbenchmark</a></span><span class='op'>)</span><span class='op'>)</span> - <span class='fu'><a href='https://rdrr.io/pkg/rbenchmark/man/benchmark.html'>benchmark</a></span><span class='op'>(</span> - analytical <span class='op'>=</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_D</span>, solution_type <span class='op'>=</span> <span class='st'>"analytical"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span>, - deSolve <span class='op'>=</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_D</span>, solution_type <span class='op'>=</span> <span class='st'>"deSolve"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span>, - replications <span class='op'>=</span> <span class='fl'>2</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Loading required package: rbenchmark</span></div><div class='output co'>#> test replications elapsed relative user.self sys.self user.child -#> 1 analytical 2 0.389 1.000 0.389 0 0 -#> 2 deSolve 2 0.690 1.774 0.690 0 0 -#> sys.child -#> 1 0 -#> 2 0</div><div class='input'> <span class='va'>DFOP_SFO</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"DFOP"</span>, <span class='st'>"m1"</span><span class='op'>)</span>, - m1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> <span class='fu'><a href='https://rdrr.io/pkg/rbenchmark/man/benchmark.html'>benchmark</a></span><span class='op'>(</span> - analytical <span class='op'>=</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>DFOP_SFO</span>, <span class='va'>FOCUS_D</span>, solution_type <span class='op'>=</span> <span class='st'>"analytical"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span>, - deSolve <span class='op'>=</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>DFOP_SFO</span>, <span class='va'>FOCUS_D</span>, solution_type <span class='op'>=</span> <span class='st'>"deSolve"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span>, - replications <span class='op'>=</span> <span class='fl'>2</span><span class='op'>)</span> -</div><div class='output co'>#> test replications elapsed relative user.self sys.self user.child -#> 1 analytical 2 0.817 1.000 0.818 0 0 -#> 2 deSolve 2 1.591 1.947 1.591 0 0 -#> sys.child -#> 1 0 -#> 2 0</div><div class='input'><span class='co'># }</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="va">SFO_SFO</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"m1"</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="va">FOCUS_D</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">FOCUS_2006_D</span>, <span class="va">value</span> <span class="op">!=</span> <span class="fl">0</span><span class="op">)</span> <span class="co"># to avoid warnings</span></span> +<span class="r-in"><span class="va">fit_1</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_D</span>, solution_type <span class="op">=</span> <span class="st">"analytical"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">fit_2</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_D</span>, solution_type <span class="op">=</span> <span class="st">"deSolve"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="kw">if</span> <span class="op">(</span><span class="kw"><a href="https://rdrr.io/r/base/library.html" class="external-link">require</a></span><span class="op">(</span><span class="va"><a href="http://rbenchmark.googlecode.com" class="external-link">rbenchmark</a></span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/pkg/rbenchmark/man/benchmark.html" class="external-link">benchmark</a></span><span class="op">(</span></span> +<span class="r-in"> analytical <span class="op">=</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_D</span>, solution_type <span class="op">=</span> <span class="st">"analytical"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span>,</span> +<span class="r-in"> deSolve <span class="op">=</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_D</span>, solution_type <span class="op">=</span> <span class="st">"deSolve"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span>,</span> +<span class="r-in"> replications <span class="op">=</span> <span class="fl">2</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Loading required package: rbenchmark</span> +<span class="r-out co"><span class="r-pr">#></span> test replications elapsed relative user.self sys.self user.child</span> +<span class="r-out co"><span class="r-pr">#></span> 1 analytical 2 0.446 1.000 0.446 0 0</span> +<span class="r-out co"><span class="r-pr">#></span> 2 deSolve 2 0.756 1.695 0.756 0 0</span> +<span class="r-out co"><span class="r-pr">#></span> sys.child</span> +<span class="r-out co"><span class="r-pr">#></span> 1 0</span> +<span class="r-out co"><span class="r-pr">#></span> 2 0</span> +<span class="r-in"> <span class="va">DFOP_SFO</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="st">"m1"</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/pkg/rbenchmark/man/benchmark.html" class="external-link">benchmark</a></span><span class="op">(</span></span> +<span class="r-in"> analytical <span class="op">=</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">DFOP_SFO</span>, <span class="va">FOCUS_D</span>, solution_type <span class="op">=</span> <span class="st">"analytical"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span>,</span> +<span class="r-in"> deSolve <span class="op">=</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">DFOP_SFO</span>, <span class="va">FOCUS_D</span>, solution_type <span class="op">=</span> <span class="st">"deSolve"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span>,</span> +<span class="r-in"> replications <span class="op">=</span> <span class="fl">2</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> test replications elapsed relative user.self sys.self user.child</span> +<span class="r-out co"><span class="r-pr">#></span> 1 analytical 2 0.896 1.000 0.896 0 0</span> +<span class="r-out co"><span class="r-pr">#></span> 2 deSolve 2 1.685 1.881 1.685 0 0</span> +<span class="r-out co"><span class="r-pr">#></span> sys.child</span> +<span class="r-out co"><span class="r-pr">#></span> 1 0</span> +<span class="r-out co"><span class="r-pr">#></span> 2 0</span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/dimethenamid_2018-1.png b/docs/reference/dimethenamid_2018-1.png Binary files differnew file mode 100644 index 00000000..338076a5 --- /dev/null +++ b/docs/reference/dimethenamid_2018-1.png diff --git a/docs/reference/dimethenamid_2018-2.png b/docs/reference/dimethenamid_2018-2.png Binary files differnew file mode 100644 index 00000000..1f41a3a8 --- /dev/null +++ b/docs/reference/dimethenamid_2018-2.png diff --git a/docs/reference/dimethenamid_2018.html b/docs/reference/dimethenamid_2018.html index 542599da..374d2287 100644 --- a/docs/reference/dimethenamid_2018.html +++ b/docs/reference/dimethenamid_2018.html @@ -1,72 +1,17 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Aerobic soil degradation data on dimethenamid and dimethenamid-P from the EU assessment in 2018 — dimethenamid_2018 • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Aerobic soil degradation data on dimethenamid and dimethenamid-P from the EU assessment in 2018 — dimethenamid_2018" /> -<meta property="og:description" content="The datasets were extracted from the active substance evaluation dossier +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Aerobic soil degradation data on dimethenamid and dimethenamid-P from the EU assessment in 2018 — dimethenamid_2018 • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Aerobic soil degradation data on dimethenamid and dimethenamid-P from the EU assessment in 2018 — dimethenamid_2018"><meta property="og:description" content="The datasets were extracted from the active substance evaluation dossier published by EFSA. Kinetic evaluations shown for these datasets are intended to illustrate and advance kinetic modelling. The fact that these data and some results are shown here does not imply a license to use them in the context of pesticide registrations, as the use of the data may be -constrained by data protection regulations." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +constrained by data protection regulations."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -77,13 +22,12 @@ constrained by data protection regulations." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.5</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -92,8 +36,7 @@ constrained by data protection regulations." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -103,6 +46,9 @@ constrained by data protection regulations." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -117,34 +63,27 @@ constrained by data protection regulations." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Aerobic soil degradation data on dimethenamid and dimethenamid-P from the EU assessment in 2018</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/dimethenamid_2018.R'><code>R/dimethenamid_2018.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/dimethenamid_2018.R" class="external-link"><code>R/dimethenamid_2018.R</code></a></small> <div class="hidden name"><code>dimethenamid_2018.Rd</code></div> </div> @@ -157,75 +96,637 @@ context of pesticide registrations, as the use of the data may be constrained by data protection regulations.</p> </div> - <pre class="usage"><span class='va'>dimethenamid_2018</span></pre> - - - <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2> - - <p>An <a href='mkindsg.html'>mkindsg</a> object grouping seven datasets with some meta information</p> - <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="va">dimethenamid_2018</span></code></pre></div> + </div> + <div id="format"> + <h2>Format</h2> + <p>An <a href="mkindsg.html">mkindsg</a> object grouping seven datasets with some meta information</p> + </div> + <div id="source"> + <h2>Source</h2> <p>Rapporteur Member State Germany, Co-Rapporteur Member State Bulgaria (2018) Renewal Assessment Report Dimethenamid-P Volume 3 - B.8 Environmental fate and behaviour Rev. 2 - November 2017 -<a href='https://open.efsa.europa.eu'>https://open.efsa.europa.eu/study-inventory/EFSA-Q-2014-00716</a></p> - <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2> - +<a href="https://open.efsa.europa.eu/study-inventory/EFSA-Q-2014-00716" class="external-link">https://open.efsa.europa.eu/study-inventory/EFSA-Q-2014-00716</a></p> + </div> + <div id="details"> + <h2>Details</h2> <p>The R code used to create this data object is installed with this package in the 'dataset_generation' directory. In the code, page numbers are given for specific pieces of information in the comments.</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>dimethenamid_2018</span><span class='op'>)</span> -</div><div class='output co'>#> <mkindsg> holding 7 mkinds objects -#> Title $title: Aerobic soil degradation data on dimethenamid-P from the EU assessment in 2018 -#> Occurrence of observed compounds $observed_n: -#> DMTAP M23 M27 M31 DMTA -#> 3 7 7 7 4 -#> Time normalisation factors $f_time_norm: -#> [1] 1.0000000 0.9706477 1.2284784 1.2284784 0.6233856 0.7678922 0.6733938 -#> Meta information $meta: -#> study usda_soil_type study_moisture_ref_type rel_moisture -#> Calke Unsworth 2014 Sandy loam pF2 1.00 -#> Borstel Staudenmaier 2009 Sand pF1 0.50 -#> Elliot 1 Wendt 1997 Clay loam pF2.5 0.75 -#> Elliot 2 Wendt 1997 Clay loam pF2.5 0.75 -#> Flaach König 1996 Sandy clay loam pF1 0.40 -#> BBA 2.2 König 1995 Loamy sand pF1 0.40 -#> BBA 2.3 König 1995 Sandy loam pF1 0.40 -#> study_ref_moisture temperature -#> Calke NA 20 -#> Borstel 23.00 20 -#> Elliot 1 33.37 23 -#> Elliot 2 33.37 23 -#> Flaach NA 20 -#> BBA 2.2 NA 20 -#> BBA 2.3 NA 20</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">dimethenamid_2018</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> <mkindsg> holding 7 mkinds objects</span> +<span class="r-out co"><span class="r-pr">#></span> Title $title: Aerobic soil degradation data on dimethenamid-P from the EU assessment in 2018 </span> +<span class="r-out co"><span class="r-pr">#></span> Occurrence of observed compounds $observed_n:</span> +<span class="r-out co"><span class="r-pr">#></span> DMTAP M23 M27 M31 DMTA </span> +<span class="r-out co"><span class="r-pr">#></span> 3 7 7 7 4 </span> +<span class="r-out co"><span class="r-pr">#></span> Time normalisation factors $f_time_norm:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] 1.0000000 0.9706477 1.2284784 1.2284784 0.6233856 0.7678922 0.6733938</span> +<span class="r-out co"><span class="r-pr">#></span> Meta information $meta:</span> +<span class="r-out co"><span class="r-pr">#></span> study usda_soil_type study_moisture_ref_type rel_moisture</span> +<span class="r-out co"><span class="r-pr">#></span> Calke Unsworth 2014 Sandy loam pF2 1.00</span> +<span class="r-out co"><span class="r-pr">#></span> Borstel Staudenmaier 2009 Sand pF1 0.50</span> +<span class="r-out co"><span class="r-pr">#></span> Elliot 1 Wendt 1997 Clay loam pF2.5 0.75</span> +<span class="r-out co"><span class="r-pr">#></span> Elliot 2 Wendt 1997 Clay loam pF2.5 0.75</span> +<span class="r-out co"><span class="r-pr">#></span> Flaach König 1996 Sandy clay loam pF1 0.40</span> +<span class="r-out co"><span class="r-pr">#></span> BBA 2.2 König 1995 Loamy sand pF1 0.40</span> +<span class="r-out co"><span class="r-pr">#></span> BBA 2.3 König 1995 Sandy loam pF1 0.40</span> +<span class="r-out co"><span class="r-pr">#></span> study_ref_moisture temperature</span> +<span class="r-out co"><span class="r-pr">#></span> Calke NA 20</span> +<span class="r-out co"><span class="r-pr">#></span> Borstel 23.00 20</span> +<span class="r-out co"><span class="r-pr">#></span> Elliot 1 33.37 23</span> +<span class="r-out co"><span class="r-pr">#></span> Elliot 2 33.37 23</span> +<span class="r-out co"><span class="r-pr">#></span> Flaach NA 20</span> +<span class="r-out co"><span class="r-pr">#></span> BBA 2.2 NA 20</span> +<span class="r-out co"><span class="r-pr">#></span> BBA 2.3 NA 20</span> +<span class="r-in"><span class="va">dmta_ds</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="fl">1</span><span class="op">:</span><span class="fl">7</span>, <span class="kw">function</span><span class="op">(</span><span class="va">i</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="va">ds_i</span> <span class="op"><-</span> <span class="va">dimethenamid_2018</span><span class="op">$</span><span class="va">ds</span><span class="op">[[</span><span class="va">i</span><span class="op">]</span><span class="op">]</span><span class="op">$</span><span class="va">data</span></span> +<span class="r-in"> <span class="va">ds_i</span><span class="op">[</span><span class="va">ds_i</span><span class="op">$</span><span class="va">name</span> <span class="op">==</span> <span class="st">"DMTAP"</span>, <span class="st">"name"</span><span class="op">]</span> <span class="op"><-</span> <span class="st">"DMTA"</span></span> +<span class="r-in"> <span class="va">ds_i</span><span class="op">$</span><span class="va">time</span> <span class="op"><-</span> <span class="va">ds_i</span><span class="op">$</span><span class="va">time</span> <span class="op">*</span> <span class="va">dimethenamid_2018</span><span class="op">$</span><span class="va">f_time_norm</span><span class="op">[</span><span class="va">i</span><span class="op">]</span></span> +<span class="r-in"> <span class="va">ds_i</span></span> +<span class="r-in"><span class="op">}</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">dmta_ds</span><span class="op">)</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">sapply</a></span><span class="op">(</span><span class="va">dimethenamid_2018</span><span class="op">$</span><span class="va">ds</span>, <span class="kw">function</span><span class="op">(</span><span class="va">ds</span><span class="op">)</span> <span class="va">ds</span><span class="op">$</span><span class="va">title</span><span class="op">)</span></span> +<span class="r-in"><span class="va">dmta_ds</span><span class="op">[[</span><span class="st">"Elliot"</span><span class="op">]</span><span class="op">]</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/cbind.html" class="external-link">rbind</a></span><span class="op">(</span><span class="va">dmta_ds</span><span class="op">[[</span><span class="st">"Elliot 1"</span><span class="op">]</span><span class="op">]</span>, <span class="va">dmta_ds</span><span class="op">[[</span><span class="st">"Elliot 2"</span><span class="op">]</span><span class="op">]</span><span class="op">)</span></span> +<span class="r-in"><span class="va">dmta_ds</span><span class="op">[[</span><span class="st">"Elliot 1"</span><span class="op">]</span><span class="op">]</span> <span class="op"><-</span> <span class="cn">NULL</span></span> +<span class="r-in"><span class="va">dmta_ds</span><span class="op">[[</span><span class="st">"Elliot 2"</span><span class="op">]</span><span class="op">]</span> <span class="op"><-</span> <span class="cn">NULL</span></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="va">dfop_sfo3_plus</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> DMTA <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"M23"</span>, <span class="st">"M27"</span>, <span class="st">"M31"</span><span class="op">)</span><span class="op">)</span>,</span> +<span class="r-in"> M23 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> M27 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> M31 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"M27"</span>, sink <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span>,</span> +<span class="r-in"> quiet <span class="op">=</span> <span class="cn">TRUE</span></span> +<span class="r-in"><span class="op">)</span></span> +<span class="r-in"><span class="va">f_dmta_mkin_tc</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="st">"DFOP-SFO3+"</span> <span class="op">=</span> <span class="va">dfop_sfo3_plus</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">dmta_ds</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"tc"</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="nlmixr.mmkin.html">nlmixr_model</a></span><span class="op">(</span><span class="va">f_dmta_mkin_tc</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> With est = 'saem', a different error model is required for each observed variableChanging the error model to 'obs_tc' (Two-component error for each observed variable)</span> +<span class="r-out co"><span class="r-pr">#></span> function () </span> +<span class="r-out co"><span class="r-pr">#></span> {</span> +<span class="r-out co"><span class="r-pr">#></span> ini({</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_0 = 99</span> +<span class="r-out co"><span class="r-pr">#></span> eta.DMTA_0 ~ 2.3</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M23 = -3.9</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M23 ~ 0.55</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M27 = -4.3</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M27 ~ 0.86</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M31 = -4.2</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M31 ~ 0.75</span> +<span class="r-out co"><span class="r-pr">#></span> log_k1 = -2.2</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k1 ~ 0.9</span> +<span class="r-out co"><span class="r-pr">#></span> log_k2 = -3.8</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k2 ~ 1.6</span> +<span class="r-out co"><span class="r-pr">#></span> g_qlogis = 0.44</span> +<span class="r-out co"><span class="r-pr">#></span> eta.g_qlogis ~ 3.1</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_1_qlogis = -2.1</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_1_qlogis ~ 0.3</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_2_qlogis = -2.2</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_2_qlogis ~ 0.3</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_3_qlogis = -2.1</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_3_qlogis ~ 0.3</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low_DMTA = 0.7</span> +<span class="r-out co"><span class="r-pr">#></span> rsd_high_DMTA = 0.026</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low_M23 = 0.7</span> +<span class="r-out co"><span class="r-pr">#></span> rsd_high_M23 = 0.026</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low_M27 = 0.7</span> +<span class="r-out co"><span class="r-pr">#></span> rsd_high_M27 = 0.026</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low_M31 = 0.7</span> +<span class="r-out co"><span class="r-pr">#></span> rsd_high_M31 = 0.026</span> +<span class="r-out co"><span class="r-pr">#></span> })</span> +<span class="r-out co"><span class="r-pr">#></span> model({</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_0_model = DMTA_0 + eta.DMTA_0</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA(0) = DMTA_0_model</span> +<span class="r-out co"><span class="r-pr">#></span> k_M23 = exp(log_k_M23 + eta.log_k_M23)</span> +<span class="r-out co"><span class="r-pr">#></span> k_M27 = exp(log_k_M27 + eta.log_k_M27)</span> +<span class="r-out co"><span class="r-pr">#></span> k_M31 = exp(log_k_M31 + eta.log_k_M31)</span> +<span class="r-out co"><span class="r-pr">#></span> k1 = exp(log_k1 + eta.log_k1)</span> +<span class="r-out co"><span class="r-pr">#></span> k2 = exp(log_k2 + eta.log_k2)</span> +<span class="r-out co"><span class="r-pr">#></span> g = expit(g_qlogis + eta.g_qlogis)</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_1 = expit(f_DMTA_tffm0_1_qlogis + eta.f_DMTA_tffm0_1_qlogis)</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_2 = expit(f_DMTA_tffm0_2_qlogis + eta.f_DMTA_tffm0_2_qlogis)</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_3 = expit(f_DMTA_tffm0_3_qlogis + eta.f_DMTA_tffm0_3_qlogis)</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_to_M23 = f_DMTA_tffm0_1</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_to_M27 = f_DMTA_tffm0_2 * (1 - f_DMTA_tffm0_1)</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_to_M31 = f_DMTA_tffm0_3 * (1 - f_DMTA_tffm0_2) * </span> +<span class="r-out co"><span class="r-pr">#></span> (1 - f_DMTA_tffm0_1)</span> +<span class="r-out co"><span class="r-pr">#></span> d/dt(DMTA) = -((k1 * g * exp(-k1 * time) + k2 * (1 - </span> +<span class="r-out co"><span class="r-pr">#></span> g) * exp(-k2 * time))/(g * exp(-k1 * time) + (1 - </span> +<span class="r-out co"><span class="r-pr">#></span> g) * exp(-k2 * time))) * DMTA</span> +<span class="r-out co"><span class="r-pr">#></span> d/dt(M23) = +f_DMTA_to_M23 * ((k1 * g * exp(-k1 * time) + </span> +<span class="r-out co"><span class="r-pr">#></span> k2 * (1 - g) * exp(-k2 * time))/(g * exp(-k1 * time) + </span> +<span class="r-out co"><span class="r-pr">#></span> (1 - g) * exp(-k2 * time))) * DMTA - k_M23 * M23</span> +<span class="r-out co"><span class="r-pr">#></span> d/dt(M27) = +f_DMTA_to_M27 * ((k1 * g * exp(-k1 * time) + </span> +<span class="r-out co"><span class="r-pr">#></span> k2 * (1 - g) * exp(-k2 * time))/(g * exp(-k1 * time) + </span> +<span class="r-out co"><span class="r-pr">#></span> (1 - g) * exp(-k2 * time))) * DMTA - k_M27 * M27 + </span> +<span class="r-out co"><span class="r-pr">#></span> k_M31 * M31</span> +<span class="r-out co"><span class="r-pr">#></span> d/dt(M31) = +f_DMTA_to_M31 * ((k1 * g * exp(-k1 * time) + </span> +<span class="r-out co"><span class="r-pr">#></span> k2 * (1 - g) * exp(-k2 * time))/(g * exp(-k1 * time) + </span> +<span class="r-out co"><span class="r-pr">#></span> (1 - g) * exp(-k2 * time))) * DMTA - k_M31 * M31</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA ~ add(sigma_low_DMTA) + prop(rsd_high_DMTA)</span> +<span class="r-out co"><span class="r-pr">#></span> M23 ~ add(sigma_low_M23) + prop(rsd_high_M23)</span> +<span class="r-out co"><span class="r-pr">#></span> M27 ~ add(sigma_low_M27) + prop(rsd_high_M27)</span> +<span class="r-out co"><span class="r-pr">#></span> M31 ~ add(sigma_low_M31) + prop(rsd_high_M31)</span> +<span class="r-out co"><span class="r-pr">#></span> })</span> +<span class="r-out co"><span class="r-pr">#></span> }</span> +<span class="r-out co"><span class="r-pr">#></span> <environment: 0x555560091f40></span> +<span class="r-in"><span class="co"># The focei fit takes about four minutes on my system</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/system.time.html" class="external-link">system.time</a></span><span class="op">(</span></span> +<span class="r-in"> <span class="va">f_dmta_nlmixr_focei</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_dmta_mkin_tc</span>, est <span class="op">=</span> <span class="st">"focei"</span>,</span> +<span class="r-in"> control <span class="op">=</span> <span class="fu">nlmixr</span><span class="fu">::</span><span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/foceiControl.html" class="external-link">foceiControl</a></span><span class="op">(</span>print <span class="op">=</span> <span class="fl">500</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> [====|====|====|====|====|====|====|====|====|====] 0:00:02 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> [====|====|====|====|====|====|====|====|====|====] 0:00:04 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> [====|====|====|====|====|====|====|====|====|====] 0:00:01 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> [====|====|====|====|====|====|====|====|====|====] 0:00:08 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> [====|====|====|====|====|====|====|====|====|====] 0:00:07 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> [====|====|====|====|====|====|====|====|====|====] 0:00:07 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> [====|====|====|====|====|====|====|====|====|====] 0:00:00 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> [====|====|====|====|====|====|====|====|====|====] 0:00:00 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-msg co"><span class="r-pr">#></span> RxODE 1.1.4 using 8 threads (see ?getRxThreads)</span> +<span class="r-msg co"><span class="r-pr">#></span> no cache: create with `rxCreateCache()`</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="font-weight: bold;">Key:</span> U: Unscaled Parameters; X: Back-transformed parameters; G: Gill difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> F: Forward difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> C: Central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> M: Mixed forward and central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> Unscaled parameters for Omegas=chol(solve(omega));</span> +<span class="r-out co"><span class="r-pr">#></span> Diagonals are transformed, as specified by foceiControl(diagXform=)</span> +<span class="r-out co"><span class="r-pr">#></span> |-----+---------------+-----------+-----------+-----------+-----------|</span> +<span class="r-out co"><span class="r-pr">#></span> | #| Objective Fun | DMTA_0 | log_k_M23 | log_k_M27 | log_k_M31 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| log_k1 | log_k2 | g_qlogis |f_DMTA_tffm0_1_qlogis |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................|f_DMTA_tffm0_2_qlogis |f_DMTA_tffm0_3_qlogis | sigma_low | rsd_high |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| o1 | o2 | o3 | o4 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| o5 | o6 | o7 | o8 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| o9 | o10 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>initial ETAs were nudged; (can control by foceiControl(etaNudge=., etaNudge2=))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>ETAs were reset to zero during optimization; (Can control by foceiControl(resetEtaP=.))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>last objective function was not at minimum, possible problems in optimization</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>S matrix non-positive definite</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>using R matrix to calculate covariance</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>gradient problems with initial estimate and covariance; see $scaleInfo</span> +<span class="r-out co"><span class="r-pr">#></span> user system elapsed </span> +<span class="r-out co"><span class="r-pr">#></span> 553.721 10.570 564.258 </span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/summary.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">f_dmta_nlmixr_focei</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> nlmixr version used for fitting: 2.0.6 </span> +<span class="r-out co"><span class="r-pr">#></span> mkin version used for pre-fitting: 1.1.0 </span> +<span class="r-out co"><span class="r-pr">#></span> R version used for fitting: 4.1.2 </span> +<span class="r-out co"><span class="r-pr">#></span> Date of fit: Wed Mar 2 13:27:22 2022 </span> +<span class="r-out co"><span class="r-pr">#></span> Date of summary: Wed Mar 2 13:27:22 2022 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Equations:</span> +<span class="r-out co"><span class="r-pr">#></span> d_DMTA/dt = - ((k1 * g * exp(-k1 * time) + k2 * (1 - g) * exp(-k2 *</span> +<span class="r-out co"><span class="r-pr">#></span> time)) / (g * exp(-k1 * time) + (1 - g) * exp(-k2 * time)))</span> +<span class="r-out co"><span class="r-pr">#></span> * DMTA</span> +<span class="r-out co"><span class="r-pr">#></span> d_M23/dt = + f_DMTA_to_M23 * ((k1 * g * exp(-k1 * time) + k2 * (1 - g)</span> +<span class="r-out co"><span class="r-pr">#></span> * exp(-k2 * time)) / (g * exp(-k1 * time) + (1 - g) *</span> +<span class="r-out co"><span class="r-pr">#></span> exp(-k2 * time))) * DMTA - k_M23 * M23</span> +<span class="r-out co"><span class="r-pr">#></span> d_M27/dt = + f_DMTA_to_M27 * ((k1 * g * exp(-k1 * time) + k2 * (1 - g)</span> +<span class="r-out co"><span class="r-pr">#></span> * exp(-k2 * time)) / (g * exp(-k1 * time) + (1 - g) *</span> +<span class="r-out co"><span class="r-pr">#></span> exp(-k2 * time))) * DMTA - k_M27 * M27 + k_M31 * M31</span> +<span class="r-out co"><span class="r-pr">#></span> d_M31/dt = + f_DMTA_to_M31 * ((k1 * g * exp(-k1 * time) + k2 * (1 - g)</span> +<span class="r-out co"><span class="r-pr">#></span> * exp(-k2 * time)) / (g * exp(-k1 * time) + (1 - g) *</span> +<span class="r-out co"><span class="r-pr">#></span> exp(-k2 * time))) * DMTA - k_M31 * M31</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Data:</span> +<span class="r-out co"><span class="r-pr">#></span> 563 observations of 4 variable(s) grouped in 6 datasets</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Degradation model predictions using RxODE</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fitted in 564.08 s</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Variance model: Two-component variance function </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Mean of starting values for individual parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_0 log_k_M23 log_k_M27 log_k_M31 f_DMTA_ilr_1 f_DMTA_ilr_2 </span> +<span class="r-out co"><span class="r-pr">#></span> 98.7132 -3.9216 -4.3306 -4.2442 0.1376 0.1388 </span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_ilr_3 log_k1 log_k2 g_qlogis </span> +<span class="r-out co"><span class="r-pr">#></span> -1.7554 -2.2352 -3.7758 0.4363 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Mean of starting values for error model parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low rsd_high </span> +<span class="r-out co"><span class="r-pr">#></span> 0.70012 0.02577 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fixed degradation parameter values:</span> +<span class="r-out co"><span class="r-pr">#></span> None</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Results:</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Likelihood calculated by focei </span> +<span class="r-out co"><span class="r-pr">#></span> AIC BIC logLik</span> +<span class="r-out co"><span class="r-pr">#></span> 1857 1952 -906.5</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Optimised parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> est. lower upper</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_0 98.0116 95.243 100.780</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M23 -4.0184 -5.213 -2.824</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M27 -4.2033 -5.013 -3.394</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M31 -4.1728 -4.999 -3.347</span> +<span class="r-out co"><span class="r-pr">#></span> log_k1 -2.4831 -3.398 -1.568</span> +<span class="r-out co"><span class="r-pr">#></span> log_k2 -3.8423 -5.450 -2.235</span> +<span class="r-out co"><span class="r-pr">#></span> g_qlogis 0.4682 -2.188 3.124</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_1_qlogis -2.0823 -2.591 -1.574</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_2_qlogis -2.1265 -2.686 -1.567</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_3_qlogis -2.0795 -2.735 -1.424</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Correlation: </span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_0 lg__M23 lg__M27 lg__M31 log_k1 log_k2 g_qlogs</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M23 -0.0154 </span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M27 -0.0164 0.0031 </span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M31 -0.0131 0.0018 0.0541 </span> +<span class="r-out co"><span class="r-pr">#></span> log_k1 -0.0306 0.0045 0.0019 0.0011 </span> +<span class="r-out co"><span class="r-pr">#></span> log_k2 0.0527 -0.0043 -0.0037 -0.0003 0.0375 </span> +<span class="r-out co"><span class="r-pr">#></span> g_qlogis -0.1005 0.0076 0.0074 0.0013 0.0910 0.1151 </span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_1_qlogis -0.0308 0.0362 0.0024 0.0021 0.0058 -0.0070 0.0145</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_2_qlogis -0.0309 0.0062 0.0353 -0.0229 0.0047 -0.0082 0.0146</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_3_qlogis -0.0308 0.0061 0.0419 0.0547 0.0033 -0.0055 0.0104</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_0_1 f_DMTA_0_2</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M23 </span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M27 </span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M31 </span> +<span class="r-out co"><span class="r-pr">#></span> log_k1 </span> +<span class="r-out co"><span class="r-pr">#></span> log_k2 </span> +<span class="r-out co"><span class="r-pr">#></span> g_qlogis </span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_1_qlogis </span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_2_qlogis 0.0118 </span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_3_qlogis 0.0086 -0.0057 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Random effects (omega):</span> +<span class="r-out co"><span class="r-pr">#></span> eta.DMTA_0 eta.log_k_M23 eta.log_k_M27 eta.log_k_M31</span> +<span class="r-out co"><span class="r-pr">#></span> eta.DMTA_0 4.224 0.000 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M23 0.000 1.041 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M27 0.000 0.000 0.4609 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M31 0.000 0.000 0.0000 0.4728</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k1 0.000 0.000 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k2 0.000 0.000 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.g_qlogis 0.000 0.000 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_1_qlogis 0.000 0.000 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_2_qlogis 0.000 0.000 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_3_qlogis 0.000 0.000 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k1 eta.log_k2 eta.g_qlogis</span> +<span class="r-out co"><span class="r-pr">#></span> eta.DMTA_0 0.000 0.000 0.00</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M23 0.000 0.000 0.00</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M27 0.000 0.000 0.00</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M31 0.000 0.000 0.00</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k1 0.635 0.000 0.00</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k2 0.000 1.662 0.00</span> +<span class="r-out co"><span class="r-pr">#></span> eta.g_qlogis 0.000 0.000 4.36</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_1_qlogis 0.000 0.000 0.00</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_2_qlogis 0.000 0.000 0.00</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_3_qlogis 0.000 0.000 0.00</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_1_qlogis eta.f_DMTA_tffm0_2_qlogis</span> +<span class="r-out co"><span class="r-pr">#></span> eta.DMTA_0 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M23 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M27 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M31 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k1 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k2 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.g_qlogis 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_1_qlogis 0.1909 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_2_qlogis 0.0000 0.2232</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_3_qlogis 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_3_qlogis</span> +<span class="r-out co"><span class="r-pr">#></span> eta.DMTA_0 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M23 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M27 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M31 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k1 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k2 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.g_qlogis 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_1_qlogis 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_2_qlogis 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_3_qlogis 0.3149</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Variance model:</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low rsd_high </span> +<span class="r-out co"><span class="r-pr">#></span> 0.82408 0.03045 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Backtransformed parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> est. lower upper</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_0 98.01163 95.243379 100.77988</span> +<span class="r-out co"><span class="r-pr">#></span> k_M23 0.01798 0.005443 0.05940</span> +<span class="r-out co"><span class="r-pr">#></span> k_M27 0.01495 0.006652 0.03358</span> +<span class="r-out co"><span class="r-pr">#></span> k_M31 0.01541 0.006746 0.03520</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_to_M23 0.11083 NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_to_M27 0.09474 NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_to_M31 0.08827 NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> k1 0.08348 0.033429 0.20848</span> +<span class="r-out co"><span class="r-pr">#></span> k2 0.02144 0.004296 0.10704</span> +<span class="r-out co"><span class="r-pr">#></span> g 0.61496 0.100857 0.95788</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Resulting formation fractions:</span> +<span class="r-out co"><span class="r-pr">#></span> ff</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_M23 0.11083</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_M27 0.09474</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_M31 0.08827</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_sink 0.70616</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Estimated disappearance times:</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90 DT50back DT50_k1 DT50_k2</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA 12.96 64.24 19.34 8.303 32.32</span> +<span class="r-out co"><span class="r-pr">#></span> M23 38.55 128.06 NA NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> M27 46.38 154.06 NA NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> M31 44.98 149.43 NA NA NA</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_dmta_nlmixr_focei</span><span class="op">)</span></span> +<span class="r-plt img"><img src="dimethenamid_2018-1.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="co"># Using saemix takes about 18 minutes</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/system.time.html" class="external-link">system.time</a></span><span class="op">(</span></span> +<span class="r-in"> <span class="va">f_dmta_saemix</span> <span class="op"><-</span> <span class="fu"><a href="saem.html">saem</a></span><span class="op">(</span><span class="va">f_dmta_mkin_tc</span>, test_log_parms <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> DINTDY- T (=R1) illegal </span> +<span class="r-out co"><span class="r-pr">#></span> In above message, R1 = 115.507</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> T not in interval TCUR - HU (= R1) to TCUR (=R2) </span> +<span class="r-out co"><span class="r-pr">#></span> In above message, R1 = 112.133, R2 = 113.577</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> DLSODA- At T (=R1), too much accuracy requested </span> +<span class="r-out co"><span class="r-pr">#></span> for precision of machine.. See TOLSF (=R2) </span> +<span class="r-out co"><span class="r-pr">#></span> In above message, R1 = 55.3899, R2 = nan</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in out[available, var]:</span> (subscript) logical subscript too long</span> +<span class="r-msg co"><span class="r-pr">#></span> Timing stopped at: 12.58 0 12.58</span> +<span class="r-msg co"><span class="r-pr">#></span> Timing stopped at: 12.99 0.008 13</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># nlmixr with est = "saem" is pretty fast with default iteration numbers, most</span></span> +<span class="r-in"><span class="co"># of the time (about 2.5 minutes) is spent for calculating the log likelihood at the end</span></span> +<span class="r-in"><span class="co"># The likelihood calculated for the nlmixr fit is much lower than that found by saemix</span></span> +<span class="r-in"><span class="co"># Also, the trace plot and the plot of the individual predictions is not</span></span> +<span class="r-in"><span class="co"># convincing for the parent. It seems we are fitting an overparameterised</span></span> +<span class="r-in"><span class="co"># model, so the result we get strongly depends on starting parameters and control settings.</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/system.time.html" class="external-link">system.time</a></span><span class="op">(</span></span> +<span class="r-in"> <span class="va">f_dmta_nlmixr_saem</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_dmta_mkin_tc</span>, est <span class="op">=</span> <span class="st">"saem"</span>,</span> +<span class="r-in"> control <span class="op">=</span> <span class="fu">nlmixr</span><span class="fu">::</span><span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/saemControl.html" class="external-link">saemControl</a></span><span class="op">(</span>print <span class="op">=</span> <span class="fl">500</span>, logLik <span class="op">=</span> <span class="cn">TRUE</span>, nmc <span class="op">=</span> <span class="fl">9</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> With est = 'saem', a different error model is required for each observed variableChanging the error model to 'obs_tc' (Two-component error for each observed variable)</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → generate SAEM model</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-out co"><span class="r-pr">#></span> 1: 98.7179 -3.4492 -3.2592 -3.6952 -2.1629 -2.7824 0.8990 -2.8080 -2.7380 -2.8041 2.7789 0.6848 0.8170 0.7125 0.8550 1.5200 2.9882 0.3073 0.2850 0.2877 4.0480 0.4153 4.5214 0.3775 4.4419 0.4181 3.7069 0.5935</span> +<span class="r-out co"><span class="r-pr">#></span> 500: 97.8519 -4.3891 -4.0888 -4.1247 -2.9246 -4.2755 2.6294 -2.1212 -2.1380 -2.0739 3.1293 1.2665 0.2763 0.3429 0.5743 1.5561 4.4991 0.1499 0.1551 0.3103 0.9514 0.0341 0.4846 0.1068 0.6597 0.0767 0.7836 0.0360</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating -2LL by Gaussian quadrature (nnodes=3,nsd=1.6)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-out co"><span class="r-pr">#></span> user system elapsed </span> +<span class="r-out co"><span class="r-pr">#></span> 785.825 3.841 153.598 </span> +<span class="r-in"><span class="fu">traceplot</span><span class="op">(</span><span class="va">f_dmta_nlmixr_saem</span><span class="op">$</span><span class="va">nm</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in traceplot(f_dmta_nlmixr_saem$nm):</span> could not find function "traceplot"</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/summary.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">f_dmta_nlmixr_saem</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> nlmixr version used for fitting: 2.0.6 </span> +<span class="r-out co"><span class="r-pr">#></span> mkin version used for pre-fitting: 1.1.0 </span> +<span class="r-out co"><span class="r-pr">#></span> R version used for fitting: 4.1.2 </span> +<span class="r-out co"><span class="r-pr">#></span> Date of fit: Wed Mar 2 13:30:09 2022 </span> +<span class="r-out co"><span class="r-pr">#></span> Date of summary: Wed Mar 2 13:30:09 2022 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Equations:</span> +<span class="r-out co"><span class="r-pr">#></span> d_DMTA/dt = - ((k1 * g * exp(-k1 * time) + k2 * (1 - g) * exp(-k2 *</span> +<span class="r-out co"><span class="r-pr">#></span> time)) / (g * exp(-k1 * time) + (1 - g) * exp(-k2 * time)))</span> +<span class="r-out co"><span class="r-pr">#></span> * DMTA</span> +<span class="r-out co"><span class="r-pr">#></span> d_M23/dt = + f_DMTA_to_M23 * ((k1 * g * exp(-k1 * time) + k2 * (1 - g)</span> +<span class="r-out co"><span class="r-pr">#></span> * exp(-k2 * time)) / (g * exp(-k1 * time) + (1 - g) *</span> +<span class="r-out co"><span class="r-pr">#></span> exp(-k2 * time))) * DMTA - k_M23 * M23</span> +<span class="r-out co"><span class="r-pr">#></span> d_M27/dt = + f_DMTA_to_M27 * ((k1 * g * exp(-k1 * time) + k2 * (1 - g)</span> +<span class="r-out co"><span class="r-pr">#></span> * exp(-k2 * time)) / (g * exp(-k1 * time) + (1 - g) *</span> +<span class="r-out co"><span class="r-pr">#></span> exp(-k2 * time))) * DMTA - k_M27 * M27 + k_M31 * M31</span> +<span class="r-out co"><span class="r-pr">#></span> d_M31/dt = + f_DMTA_to_M31 * ((k1 * g * exp(-k1 * time) + k2 * (1 - g)</span> +<span class="r-out co"><span class="r-pr">#></span> * exp(-k2 * time)) / (g * exp(-k1 * time) + (1 - g) *</span> +<span class="r-out co"><span class="r-pr">#></span> exp(-k2 * time))) * DMTA - k_M31 * M31</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Data:</span> +<span class="r-out co"><span class="r-pr">#></span> 563 observations of 4 variable(s) grouped in 6 datasets</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Degradation model predictions using RxODE</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fitted in 153.313 s</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Variance model: Two-component variance function </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Mean of starting values for individual parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_0 log_k_M23 log_k_M27 log_k_M31 f_DMTA_ilr_1 f_DMTA_ilr_2 </span> +<span class="r-out co"><span class="r-pr">#></span> 98.7132 -3.9216 -4.3306 -4.2442 0.1376 0.1388 </span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_ilr_3 log_k1 log_k2 g_qlogis </span> +<span class="r-out co"><span class="r-pr">#></span> -1.7554 -2.2352 -3.7758 0.4363 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Mean of starting values for error model parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low_DMTA rsd_high_DMTA sigma_low_M23 rsd_high_M23 sigma_low_M27 </span> +<span class="r-out co"><span class="r-pr">#></span> 0.70012 0.02577 0.70012 0.02577 0.70012 </span> +<span class="r-out co"><span class="r-pr">#></span> rsd_high_M27 sigma_low_M31 rsd_high_M31 </span> +<span class="r-out co"><span class="r-pr">#></span> 0.02577 0.70012 0.02577 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fixed degradation parameter values:</span> +<span class="r-out co"><span class="r-pr">#></span> None</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Results:</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Likelihood calculated by focei </span> +<span class="r-out co"><span class="r-pr">#></span> AIC BIC logLik</span> +<span class="r-out co"><span class="r-pr">#></span> 1966 2088 -955.2</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Optimised parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> est. lower upper</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_0 97.852 95.86386 99.840</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M23 -4.389 -5.35084 -3.427</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M27 -4.089 -4.54432 -3.633</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M31 -4.125 -4.63280 -3.617</span> +<span class="r-out co"><span class="r-pr">#></span> log_k1 -2.925 -3.54158 -2.308</span> +<span class="r-out co"><span class="r-pr">#></span> log_k2 -4.275 -5.81760 -2.733</span> +<span class="r-out co"><span class="r-pr">#></span> g_qlogis 2.629 -0.01785 5.277</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_1_qlogis -2.121 -2.44462 -1.798</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_2_qlogis -2.138 -2.47804 -1.798</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_3_qlogis -2.074 -2.53581 -1.612</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Correlation: </span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_0 lg__M23 lg__M27 lg__M31 log_k1 log_k2 g_qlogs</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M23 -0.0164 </span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M27 -0.0267 0.0028 </span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M31 -0.0179 0.0023 0.0755 </span> +<span class="r-out co"><span class="r-pr">#></span> log_k1 0.0385 -0.0034 -0.0054 -0.0029 </span> +<span class="r-out co"><span class="r-pr">#></span> log_k2 0.0381 0.0115 0.0087 0.0093 0.0786 </span> +<span class="r-out co"><span class="r-pr">#></span> g_qlogis -0.0656 0.0021 0.0051 0.0001 -0.1177 -0.4389 </span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_1_qlogis -0.0604 0.0554 0.0054 0.0039 -0.0082 -0.0022 0.0119</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_2_qlogis -0.0601 0.0091 0.0577 -0.0350 -0.0081 -0.0057 0.0137</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_3_qlogis -0.0515 0.0083 0.0569 0.0729 -0.0059 0.0005 0.0073</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_0_1 f_DMTA_0_2</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M23 </span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M27 </span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M31 </span> +<span class="r-out co"><span class="r-pr">#></span> log_k1 </span> +<span class="r-out co"><span class="r-pr">#></span> log_k2 </span> +<span class="r-out co"><span class="r-pr">#></span> g_qlogis </span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_1_qlogis </span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_2_qlogis 0.0167 </span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_3_qlogis 0.0145 -0.0060 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Random effects (omega):</span> +<span class="r-out co"><span class="r-pr">#></span> eta.DMTA_0 eta.log_k_M23 eta.log_k_M27 eta.log_k_M31</span> +<span class="r-out co"><span class="r-pr">#></span> eta.DMTA_0 3.129 0.000 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M23 0.000 1.266 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M27 0.000 0.000 0.2763 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M31 0.000 0.000 0.0000 0.3429</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k1 0.000 0.000 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k2 0.000 0.000 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.g_qlogis 0.000 0.000 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_1_qlogis 0.000 0.000 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_2_qlogis 0.000 0.000 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_3_qlogis 0.000 0.000 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k1 eta.log_k2 eta.g_qlogis</span> +<span class="r-out co"><span class="r-pr">#></span> eta.DMTA_0 0.0000 0.000 0.000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M23 0.0000 0.000 0.000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M27 0.0000 0.000 0.000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M31 0.0000 0.000 0.000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k1 0.5743 0.000 0.000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k2 0.0000 1.556 0.000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.g_qlogis 0.0000 0.000 4.499</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_1_qlogis 0.0000 0.000 0.000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_2_qlogis 0.0000 0.000 0.000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_3_qlogis 0.0000 0.000 0.000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_1_qlogis eta.f_DMTA_tffm0_2_qlogis</span> +<span class="r-out co"><span class="r-pr">#></span> eta.DMTA_0 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M23 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M27 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M31 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k1 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k2 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.g_qlogis 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_1_qlogis 0.1499 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_2_qlogis 0.0000 0.1551</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_3_qlogis 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_3_qlogis</span> +<span class="r-out co"><span class="r-pr">#></span> eta.DMTA_0 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M23 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M27 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M31 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k1 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k2 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.g_qlogis 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_1_qlogis 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_2_qlogis 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_3_qlogis 0.3103</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Variance model:</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low_DMTA rsd_high_DMTA sigma_low_M23 rsd_high_M23 sigma_low_M27 </span> +<span class="r-out co"><span class="r-pr">#></span> 0.95135 0.03412 0.48455 0.10682 0.65969 </span> +<span class="r-out co"><span class="r-pr">#></span> rsd_high_M27 sigma_low_M31 rsd_high_M31 </span> +<span class="r-out co"><span class="r-pr">#></span> 0.07670 0.78365 0.03598 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Backtransformed parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> est. lower upper</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_0 97.85189 95.863863 99.83992</span> +<span class="r-out co"><span class="r-pr">#></span> k_M23 0.01241 0.004744 0.03247</span> +<span class="r-out co"><span class="r-pr">#></span> k_M27 0.01676 0.010627 0.02643</span> +<span class="r-out co"><span class="r-pr">#></span> k_M31 0.01617 0.009727 0.02687</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_to_M23 0.10705 NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_to_M27 0.09417 NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_to_M31 0.08919 NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> k1 0.05369 0.028968 0.09950</span> +<span class="r-out co"><span class="r-pr">#></span> k2 0.01391 0.002975 0.06500</span> +<span class="r-out co"><span class="r-pr">#></span> g 0.93273 0.495538 0.99492</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Resulting formation fractions:</span> +<span class="r-out co"><span class="r-pr">#></span> ff</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_M23 0.10705</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_M27 0.09417</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_M31 0.08919</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_sink 0.70959</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Estimated disappearance times:</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90 DT50back DT50_k1 DT50_k2</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA 13.81 49.3 14.84 12.91 49.85</span> +<span class="r-out co"><span class="r-pr">#></span> M23 55.85 185.5 NA NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> M27 41.36 137.4 NA NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> M31 42.87 142.4 NA NA NA</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_dmta_nlmixr_saem</span><span class="op">)</span></span> +<span class="r-plt img"><img src="dimethenamid_2018-2.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/endpoints.html b/docs/reference/endpoints.html index bfe030b0..1476eed8 100644 --- a/docs/reference/endpoints.html +++ b/docs/reference/endpoints.html @@ -1,73 +1,18 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Function to calculate endpoints for further use from kinetic models fitted -with mkinfit — endpoints • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Function to calculate endpoints for further use from kinetic models fitted -with mkinfit — endpoints" /> -<meta property="og:description" content="This function calculates DT50 and DT90 values as well as formation fractions +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Function to calculate endpoints for further use from kinetic models fitted +with mkinfit — endpoints • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Function to calculate endpoints for further use from kinetic models fitted +with mkinfit — endpoints"><meta property="og:description" content="This function calculates DT50 and DT90 values as well as formation fractions from kinetic models fitted with mkinfit. If the SFORB model was specified for one of the parents or metabolites, the Eigenvalues are returned. These are equivalent to the rate constants of the DFOP model, but with the -advantage that the SFORB model can also be used for metabolites." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +advantage that the SFORB model can also be used for metabolites."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -78,13 +23,12 @@ advantage that the SFORB model can also be used for metabolites." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.5</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -93,8 +37,7 @@ advantage that the SFORB model can also be used for metabolites." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -104,6 +47,9 @@ advantage that the SFORB model can also be used for metabolites." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -118,35 +64,28 @@ advantage that the SFORB model can also be used for metabolites." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Function to calculate endpoints for further use from kinetic models fitted with mkinfit</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/endpoints.R'><code>R/endpoints.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/endpoints.R" class="external-link"><code>R/endpoints.R</code></a></small> <div class="hidden name"><code>endpoints.Rd</code></div> </div> @@ -158,93 +97,96 @@ are equivalent to the rate constants of the DFOP model, but with the advantage that the SFORB model can also be used for metabolites.</p> </div> - <pre class="usage"><span class='fu'>endpoints</span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">endpoints</span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>fit</th> - <td><p>An object of class <a href='mkinfit.html'>mkinfit</a> or <a href='nlme.mmkin.html'>nlme.mmkin</a> -or another object that has list components -mkinmod containing an <a href='mkinmod.html'>mkinmod</a> degradation model, and two numeric vectors, + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>fit</dt> +<dd><p>An object of class <a href="mkinfit.html">mkinfit</a>, <a href="nlme.mmkin.html">nlme.mmkin</a>, <a href="saem.html">saem.mmkin</a> or +<a href="nlmixr.mmkin.html">nlmixr.mmkin</a>. Or another object that has list components +mkinmod containing an <a href="mkinmod.html">mkinmod</a> degradation model, and two numeric vectors, bparms.optim and bparms.fixed, that contain parameter values -for that model.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - +for that model.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>A list with a matrix of dissipation times named distimes, and, if applicable, a vector of formation fractions named ff and, if the SFORB model was in use, a vector of eigenvalues of these SFORB models, equivalent to DFOP rate constants</p> - <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2> - + </div> + <div id="details"> + <h2>Details</h2> <p>Additional DT50 values are calculated from the FOMC DT90 and k1 and k2 from HS and DFOP, as well as from Eigenvalues b1 and b2 of any SFORB models</p> - <h2 class="hasAnchor" id="note"><a class="anchor" href="#note"></a>Note</h2> - - <p>The function is used internally by <a href='summary.mkinfit.html'>summary.mkinfit</a> -and <a href='summary.nlme.mmkin.html'>summary.nlme.mmkin</a></p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="note"> + <h2>Note</h2> + <p>The function is used internally by <a href="summary.mkinfit.html">summary.mkinfit</a>, +<a href="summary.nlme.mmkin.html">summary.nlme.mmkin</a> and <a href="summary.saem.mmkin.html">summary.saem.mmkin</a>.</p> + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> - <span class='va'>fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"FOMC"</span>, <span class='va'>FOCUS_2006_C</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - <span class='fu'>endpoints</span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span> -</div><div class='output co'>#> $distimes -#> DT50 DT90 DT50back -#> parent 1.785233 15.1479 4.559973 -#> </div><div class='input'> <span class='co'># \dontrun{</span> - <span class='va'>fit_2</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"DFOP"</span>, <span class='va'>FOCUS_2006_C</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - <span class='fu'>endpoints</span><span class='op'>(</span><span class='va'>fit_2</span><span class='op'>)</span> -</div><div class='output co'>#> $distimes -#> DT50 DT90 DT50back DT50_k1 DT50_k2 -#> parent 1.886925 21.25106 6.397207 1.508293 38.83438 -#> </div><div class='input'> <span class='va'>fit_3</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"SFORB"</span>, <span class='va'>FOCUS_2006_C</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - <span class='fu'>endpoints</span><span class='op'>(</span><span class='va'>fit_3</span><span class='op'>)</span> -</div><div class='output co'>#> $ff -#> parent_free -#> 1 -#> -#> $SFORB -#> parent_b1 parent_b2 -#> 0.4595574 0.0178488 -#> -#> $distimes -#> DT50 DT90 DT50back DT50_parent_b1 DT50_parent_b2 -#> parent 1.886925 21.25106 6.397208 1.508293 38.83438 -#> </div><div class='input'> <span class='co'># }</span> - -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"> <span class="va">fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"FOMC"</span>, <span class="va">FOCUS_2006_C</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu">endpoints</span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> $distimes</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90 DT50back</span> +<span class="r-out co"><span class="r-pr">#></span> parent 1.785233 15.1479 4.559973</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"> <span class="co"># \dontrun{</span></span> +<span class="r-in"> <span class="va">fit_2</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="va">FOCUS_2006_C</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu">endpoints</span><span class="op">(</span><span class="va">fit_2</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> $distimes</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90 DT50back DT50_k1 DT50_k2</span> +<span class="r-out co"><span class="r-pr">#></span> parent 1.886925 21.25106 6.397207 1.508293 38.83438</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"> <span class="va">fit_3</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"SFORB"</span>, <span class="va">FOCUS_2006_C</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu">endpoints</span><span class="op">(</span><span class="va">fit_3</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> $ff</span> +<span class="r-out co"><span class="r-pr">#></span> parent_free </span> +<span class="r-out co"><span class="r-pr">#></span> 1 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $SFORB</span> +<span class="r-out co"><span class="r-pr">#></span> parent_b1 parent_b2 </span> +<span class="r-out co"><span class="r-pr">#></span> 0.4595574 0.0178488 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $distimes</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90 DT50back DT50_parent_b1 DT50_parent_b2</span> +<span class="r-out co"><span class="r-pr">#></span> parent 1.886925 21.25106 6.397208 1.508293 38.83438</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"> <span class="co"># }</span></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/experimental_data_for_UBA-1.png b/docs/reference/experimental_data_for_UBA-1.png Binary files differindex 5527c07f..b7b4d63b 100644 --- a/docs/reference/experimental_data_for_UBA-1.png +++ b/docs/reference/experimental_data_for_UBA-1.png diff --git a/docs/reference/experimental_data_for_UBA.html b/docs/reference/experimental_data_for_UBA.html index 4da8d6c3..862c63e4 100644 --- a/docs/reference/experimental_data_for_UBA.html +++ b/docs/reference/experimental_data_for_UBA.html @@ -1,46 +1,5 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Experimental datasets used for development and testing of error models — experimental_data_for_UBA_2019 • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Experimental datasets used for development and testing of error models — experimental_data_for_UBA_2019" /> -<meta property="og:description" content="The 12 datasets were extracted from active substance evaluation dossiers published +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Experimental datasets used for development and testing of error models — experimental_data_for_UBA_2019 • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Experimental datasets used for development and testing of error models — experimental_data_for_UBA_2019"><meta property="og:description" content="The 12 datasets were extracted from active substance evaluation dossiers published by EFSA. Kinetic evaluations shown for these datasets are intended to illustrate and advance error model specifications. The fact that these data and some results are shown here do not imply a license to use them in the context of @@ -68,28 +27,14 @@ Dataset 11 is from the Renewal Assessment Report (RAR) for 2,4-D the exception of the day three sampling of metabolite A2, which was set to one half of the LOD reported to be 1% AR. Dataset 12 is from the Renewal Assessment Report (RAR) for thifensulfuron-methyl - (United Kingdom, 2014, p. 81)." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> + (United Kingdom, 2014, p. 81)."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -100,13 +45,12 @@ Dataset 12 is from the Renewal Assessment Report (RAR) for thifensulfuron-methyl </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -115,8 +59,7 @@ Dataset 12 is from the Renewal Assessment Report (RAR) for thifensulfuron-methyl <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -126,6 +69,9 @@ Dataset 12 is from the Renewal Assessment Report (RAR) for thifensulfuron-methyl <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -140,30 +86,23 @@ Dataset 12 is from the Renewal Assessment Report (RAR) for thifensulfuron-methyl <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Experimental datasets used for development and testing of error models</h1> @@ -203,30 +142,33 @@ Dataset 12 is from the Renewal Assessment Report (RAR) for thifensulfuron-methyl (United Kingdom, 2014, p. 81).</p> </div> - <pre class="usage"><span class='va'>experimental_data_for_UBA_2019</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="va">experimental_data_for_UBA_2019</span></code></pre></div> + </div> + <div id="format"> + <h2>Format</h2> + <p>A list containing twelve datasets as an R6 class defined by <code><a href="mkinds.html">mkinds</a></code>, + each containing, among others, the following components</p><dl><dt><code>title</code></dt> +<dd><p>The name of the dataset, e.g. <code>Soil 1</code></p></dd> - <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2> + <dt><code>data</code></dt> +<dd><p>A data frame with the data in the form expected by <code><a href="mkinfit.html">mkinfit</a></code></p></dd> - <p>A list containing twelve datasets as an R6 class defined by <code><a href='mkinds.html'>mkinds</a></code>, - each containing, among others, the following components</p><dl> - <dt><code>title</code></dt><dd><p>The name of the dataset, e.g. <code>Soil 1</code></p></dd> - <dt><code>data</code></dt><dd><p>A data frame with the data in the form expected by <code><a href='mkinfit.html'>mkinfit</a></code></p></dd> -</dl> - - <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2> - +</dl></div> + <div id="source"> + <h2>Source</h2> <p>Austria (2015). Ethofumesate Renewal Assessment Report Volume 3 Annex B.8 (AS)</p> <p>Belgium (2014). Isofetamid (IKF-5411) Draft Assessment Report Volume 3 Annex B.8 (AS)</p> <p>France (2015). Imazamox Draft Renewal Assessment Report Volume 3 Annex B.8 (AS)</p> -<p>FOCUS (2014) “Generic guidance for Estimating Persistence and +<p>FOCUS (2014) “Generic guidance for Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in EU - Registration” Report of the FOCUS Work Group on Degradation Kinetics, + Registration” Report of the FOCUS Work Group on Degradation Kinetics, Version 1.1, 18 December 2014 - <a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + <a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> <p>Germany (2013). Renewal Assessment Report Glyphosate Volume 3 Annex B.8: Environmental Fate and Behaviour</p> <p>Hellas (2013). Renewal Assessment Report 2,4-D Volume 3 Annex B.8: Fate and behaviour in the @@ -236,70 +178,75 @@ Dataset 12 is from the Renewal Assessment Report (RAR) for thifensulfuron-methyl <p>United Kingdom (2014). Thifensulfuron-methyl - Annex B.8 (Volume 3) to the Report and Proposed Decision of the United Kingdom made to the European Commission under Regulation (EC) No. 1141/2010 for renewal of an active substance</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='co'># \dontrun{</span> - -<span class='co'># Model definitions</span> -<span class='va'>sfo_sfo</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"A1"</span><span class='op'>)</span>, - A1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, - use_of_ff <span class='op'>=</span> <span class='st'>"max"</span> -<span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> -<span class='va'>dfop_sfo</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"DFOP"</span>, to <span class='op'>=</span> <span class='st'>"A1"</span><span class='op'>)</span>, - A1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, - use_of_ff <span class='op'>=</span> <span class='st'>"max"</span> -<span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> -<span class='va'>sfo_sfo_sfo</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"A1"</span><span class='op'>)</span>, - A1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"A2"</span><span class='op'>)</span>, - A2 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, - use_of_ff <span class='op'>=</span> <span class='st'>"max"</span> -<span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> -<span class='va'>dfop_sfo_sfo</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"DFOP"</span>, to <span class='op'>=</span> <span class='st'>"A1"</span><span class='op'>)</span>, - A1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"A2"</span><span class='op'>)</span>, - A2 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, - use_of_ff <span class='op'>=</span> <span class='st'>"max"</span> -<span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'><span class='va'>d_1_2</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/lapply.html'>lapply</a></span><span class='op'>(</span><span class='va'>experimental_data_for_UBA_2019</span><span class='op'>[</span><span class='fl'>1</span><span class='op'>:</span><span class='fl'>2</span><span class='op'>]</span>, <span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='va'>x</span><span class='op'>$</span><span class='va'>data</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/names.html'>names</a></span><span class='op'>(</span><span class='va'>d_1_2</span><span class='op'>)</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/paste.html'>paste</a></span><span class='op'>(</span><span class='st'>"Soil"</span>, <span class='fl'>1</span><span class='op'>:</span><span class='fl'>2</span><span class='op'>)</span> - - -<span class='va'>f_1_2_tc</span> <span class='op'><-</span> <span class='fu'><a href='mmkin.html'>mmkin</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span><span class='st'>"DFOP-SFO-SFO"</span> <span class='op'>=</span> <span class='va'>dfop_sfo_sfo</span><span class='op'>)</span>, <span class='va'>d_1_2</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span><span class='op'>)</span> - -<span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>f_1_2_tc</span>, resplot <span class='op'>=</span> <span class='st'>"errmod"</span><span class='op'>)</span> -</div><div class='img'><img src='experimental_data_for_UBA-1.png' alt='' width='700' height='433' /></div><div class='input'> -<span class='co'># }</span></div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Model definitions</span></span> +<span class="r-in"><span class="va">sfo_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"A1"</span><span class="op">)</span>,</span> +<span class="r-in"> A1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> use_of_ff <span class="op">=</span> <span class="st">"max"</span></span> +<span class="r-in"><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">dfop_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"DFOP"</span>, to <span class="op">=</span> <span class="st">"A1"</span><span class="op">)</span>,</span> +<span class="r-in"> A1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> use_of_ff <span class="op">=</span> <span class="st">"max"</span></span> +<span class="r-in"><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">sfo_sfo_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"A1"</span><span class="op">)</span>,</span> +<span class="r-in"> A1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"A2"</span><span class="op">)</span>,</span> +<span class="r-in"> A2 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> use_of_ff <span class="op">=</span> <span class="st">"max"</span></span> +<span class="r-in"><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">dfop_sfo_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"DFOP"</span>, to <span class="op">=</span> <span class="st">"A1"</span><span class="op">)</span>,</span> +<span class="r-in"> A1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"A2"</span><span class="op">)</span>,</span> +<span class="r-in"> A2 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> use_of_ff <span class="op">=</span> <span class="st">"max"</span></span> +<span class="r-in"><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="va">d_1_2</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="va">experimental_data_for_UBA_2019</span><span class="op">[</span><span class="fl">1</span><span class="op">:</span><span class="fl">2</span><span class="op">]</span>, <span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="va">x</span><span class="op">$</span><span class="va">data</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">d_1_2</span><span class="op">)</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste</a></span><span class="op">(</span><span class="st">"Soil"</span>, <span class="fl">1</span><span class="op">:</span><span class="fl">2</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">f_1_2_tc</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="st">"DFOP-SFO-SFO"</span> <span class="op">=</span> <span class="va">dfop_sfo_sfo</span><span class="op">)</span>, <span class="va">d_1_2</span>, error_model <span class="op">=</span> <span class="st">"tc"</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_1_2_tc</span>, resplot <span class="op">=</span> <span class="st">"errmod"</span><span class="op">)</span></span> +<span class="r-plt img"><img src="experimental_data_for_UBA-1.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/f_time_norm_focus.html b/docs/reference/f_time_norm_focus.html index a0899ac8..4bec2bd5 100644 --- a/docs/reference/f_time_norm_focus.html +++ b/docs/reference/f_time_norm_focus.html @@ -1,68 +1,13 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Normalisation factors for aerobic soil degradation according to FOCUS guidance — f_time_norm_focus • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Normalisation factors for aerobic soil degradation according to FOCUS guidance — f_time_norm_focus" /> -<meta property="og:description" content="Time step normalisation factors for aerobic soil degradation as described -in Appendix 8 to the FOCUS kinetics guidance (FOCUS 2014, p. 369)." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Normalisation factors for aerobic soil degradation according to FOCUS guidance — f_time_norm_focus • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Normalisation factors for aerobic soil degradation according to FOCUS guidance — f_time_norm_focus"><meta property="og:description" content="Time step normalisation factors for aerobic soil degradation as described +in Appendix 8 to the FOCUS kinetics guidance (FOCUS 2014, p. 369)."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -73,13 +18,12 @@ in Appendix 8 to the FOCUS kinetics guidance (FOCUS 2014, p. 369)." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -88,8 +32,7 @@ in Appendix 8 to the FOCUS kinetics guidance (FOCUS 2014, p. 369)." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -99,6 +42,9 @@ in Appendix 8 to the FOCUS kinetics guidance (FOCUS 2014, p. 369)." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -113,34 +59,27 @@ in Appendix 8 to the FOCUS kinetics guidance (FOCUS 2014, p. 369)." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Normalisation factors for aerobic soil degradation according to FOCUS guidance</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/f_time_norm_focus.R'><code>R/f_time_norm_focus.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/f_time_norm_focus.R" class="external-link"><code>R/f_time_norm_focus.R</code></a></small> <div class="hidden name"><code>f_time_norm_focus.Rd</code></div> </div> @@ -149,137 +88,121 @@ in Appendix 8 to the FOCUS kinetics guidance (FOCUS 2014, p. 369)." /> in Appendix 8 to the FOCUS kinetics guidance (FOCUS 2014, p. 369).</p> </div> - <pre class="usage"><span class='fu'>f_time_norm_focus</span><span class='op'>(</span><span class='va'>object</span>, <span class='va'>...</span><span class='op'>)</span> - -<span class='co'># S3 method for numeric</span> -<span class='fu'>f_time_norm_focus</span><span class='op'>(</span> - <span class='va'>object</span>, - moisture <span class='op'>=</span> <span class='cn'>NA</span>, - field_moisture <span class='op'>=</span> <span class='cn'>NA</span>, - temperature <span class='op'>=</span> <span class='va'>object</span>, - Q10 <span class='op'>=</span> <span class='fl'>2.58</span>, - walker <span class='op'>=</span> <span class='fl'>0.7</span>, - f_na <span class='op'>=</span> <span class='cn'>NA</span>, - <span class='va'>...</span> -<span class='op'>)</span> - -<span class='co'># S3 method for mkindsg</span> -<span class='fu'>f_time_norm_focus</span><span class='op'>(</span> - <span class='va'>object</span>, - study_moisture_ref_source <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"auto"</span>, <span class='st'>"meta"</span>, <span class='st'>"focus"</span><span class='op'>)</span>, - Q10 <span class='op'>=</span> <span class='fl'>2.58</span>, - walker <span class='op'>=</span> <span class='fl'>0.7</span>, - f_na <span class='op'>=</span> <span class='cn'>NA</span>, - <span class='va'>...</span> -<span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">f_time_norm_focus</span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span><span class="op">)</span> + +<span class="co"># S3 method for numeric</span> +<span class="fu">f_time_norm_focus</span><span class="op">(</span> + <span class="va">object</span>, + moisture <span class="op">=</span> <span class="cn">NA</span>, + field_moisture <span class="op">=</span> <span class="cn">NA</span>, + temperature <span class="op">=</span> <span class="va">object</span>, + Q10 <span class="op">=</span> <span class="fl">2.58</span>, + walker <span class="op">=</span> <span class="fl">0.7</span>, + f_na <span class="op">=</span> <span class="cn">NA</span>, + <span class="va">...</span> +<span class="op">)</span> + +<span class="co"># S3 method for mkindsg</span> +<span class="fu">f_time_norm_focus</span><span class="op">(</span> + <span class="va">object</span>, + study_moisture_ref_source <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"auto"</span>, <span class="st">"meta"</span>, <span class="st">"focus"</span><span class="op">)</span>, + Q10 <span class="op">=</span> <span class="fl">2.58</span>, + walker <span class="op">=</span> <span class="fl">0.7</span>, + f_na <span class="op">=</span> <span class="cn">NA</span>, + <span class="va">...</span> +<span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>An object containing information used for the calculations</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Currently not used</p></td> - </tr> - <tr> - <th>moisture</th> - <td><p>Numeric vector of moisture contents in \% w/w</p></td> - </tr> - <tr> - <th>field_moisture</th> - <td><p>Numeric vector of moisture contents at field capacity -(pF2) in \% w/w</p></td> - </tr> - <tr> - <th>temperature</th> - <td><p>Numeric vector of temperatures in °C</p></td> - </tr> - <tr> - <th>Q10</th> - <td><p>The Q10 value used for temperature normalisation</p></td> - </tr> - <tr> - <th>walker</th> - <td><p>The Walker exponent used for moisture normalisation</p></td> - </tr> - <tr> - <th>f_na</th> - <td><p>The factor to use for NA values. If set to NA, only factors -for complete cases will be returned.</p></td> - </tr> - <tr> - <th>study_moisture_ref_source</th> - <td><p>Source for the reference value + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>An object containing information used for the calculations</p></dd> +<dt>...</dt> +<dd><p>Currently not used</p></dd> +<dt>moisture</dt> +<dd><p>Numeric vector of moisture contents in \% w/w</p></dd> +<dt>field_moisture</dt> +<dd><p>Numeric vector of moisture contents at field capacity +(pF2) in \% w/w</p></dd> +<dt>temperature</dt> +<dd><p>Numeric vector of temperatures in °C</p></dd> +<dt>Q10</dt> +<dd><p>The Q10 value used for temperature normalisation</p></dd> +<dt>walker</dt> +<dd><p>The Walker exponent used for moisture normalisation</p></dd> +<dt>f_na</dt> +<dd><p>The factor to use for NA values. If set to NA, only factors +for complete cases will be returned.</p></dd> +<dt>study_moisture_ref_source</dt> +<dd><p>Source for the reference value used to calculate the study moisture. If 'auto', preference is given to a reference moisture given in the meta information, otherwise -the focus soil moisture for the soil class is used</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - - <p>FOCUS (2006) “Guidance Document on Estimating Persistence +the focus soil moisture for the soil class is used</p></dd> +</dl></div> + <div id="references"> + <h2>References</h2> + <p>FOCUS (2006) “Guidance Document on Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC Document Reference Sanco/10058/2005 version 2.0, 434 pp, -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a> -FOCUS (2014) “Generic guidance for Estimating Persistence +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a> +FOCUS (2014) “Generic guidance for Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, Version 1.1, 18 December 2014 -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p><a href='focus_soil_moisture.html'>focus_soil_moisture</a></p></div> +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p><a href="focus_soil_moisture.html">focus_soil_moisture</a></p></div> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='fu'>f_time_norm_focus</span><span class='op'>(</span><span class='fl'>25</span>, <span class='fl'>20</span>, <span class='fl'>25</span><span class='op'>)</span> <span class='co'># 1.37, compare FOCUS 2014 p. 184</span> -</div><div class='output co'>#> [1] 1.373956</div><div class='input'> -<span class='va'>D24_2014</span><span class='op'>$</span><span class='va'>meta</span> -</div><div class='output co'>#> study usda_soil_type study_moisture_ref_type -#> Mississippi Cohen 1991 Silt loam <NA> -#> Fayette Liu and Adelfinskaya 2011 Silt loam pF1 -#> RefSol 03-G Liu and Adelfinskaya 2011 Loam pF1 -#> Site E1 Liu and Adelfinskaya 2011 Loam pF1 -#> Site I2 Liu and Adelfinskaya 2011 Loamy sand pF1 -#> rel_moisture temperature -#> Mississippi NA 25 -#> Fayette 0.5 20 -#> RefSol 03-G 0.5 20 -#> Site E1 0.5 20 -#> Site I2 0.5 20</div><div class='input'><span class='co'># No moisture normalisation in the first dataset, so we use f_na = 1 to get</span> -<span class='co'># temperature only normalisation as in the EU evaluation</span> -<span class='fu'>f_time_norm_focus</span><span class='op'>(</span><span class='va'>D24_2014</span>, study_moisture_ref_source <span class='op'>=</span> <span class='st'>"focus"</span>, f_na <span class='op'>=</span> <span class='fl'>1</span><span class='op'>)</span> -</div><div class='output co'>#> $time_norm was set to -#> [1] 1.6062378 0.7118732 0.7156063 0.7156063 0.8977124</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="fu">f_time_norm_focus</span><span class="op">(</span><span class="fl">25</span>, <span class="fl">20</span>, <span class="fl">25</span><span class="op">)</span> <span class="co"># 1.37, compare FOCUS 2014 p. 184</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 1.373956</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">D24_2014</span><span class="op">$</span><span class="va">meta</span></span> +<span class="r-out co"><span class="r-pr">#></span> study usda_soil_type study_moisture_ref_type</span> +<span class="r-out co"><span class="r-pr">#></span> Mississippi Cohen 1991 Silt loam <NA></span> +<span class="r-out co"><span class="r-pr">#></span> Fayette Liu and Adelfinskaya 2011 Silt loam pF1</span> +<span class="r-out co"><span class="r-pr">#></span> RefSol 03-G Liu and Adelfinskaya 2011 Loam pF1</span> +<span class="r-out co"><span class="r-pr">#></span> Site E1 Liu and Adelfinskaya 2011 Loam pF1</span> +<span class="r-out co"><span class="r-pr">#></span> Site I2 Liu and Adelfinskaya 2011 Loamy sand pF1</span> +<span class="r-out co"><span class="r-pr">#></span> rel_moisture temperature</span> +<span class="r-out co"><span class="r-pr">#></span> Mississippi NA 25</span> +<span class="r-out co"><span class="r-pr">#></span> Fayette 0.5 20</span> +<span class="r-out co"><span class="r-pr">#></span> RefSol 03-G 0.5 20</span> +<span class="r-out co"><span class="r-pr">#></span> Site E1 0.5 20</span> +<span class="r-out co"><span class="r-pr">#></span> Site I2 0.5 20</span> +<span class="r-in"><span class="co"># No moisture normalisation in the first dataset, so we use f_na = 1 to get</span></span> +<span class="r-in"><span class="co"># temperature only normalisation as in the EU evaluation</span></span> +<span class="r-in"><span class="fu">f_time_norm_focus</span><span class="op">(</span><span class="va">D24_2014</span>, study_moisture_ref_source <span class="op">=</span> <span class="st">"focus"</span>, f_na <span class="op">=</span> <span class="fl">1</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> $f_time_norm was (re)set to normalised values</span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/focus_soil_moisture.html b/docs/reference/focus_soil_moisture.html index bbacc554..726f87c4 100644 --- a/docs/reference/focus_soil_moisture.html +++ b/docs/reference/focus_soil_moisture.html @@ -1,68 +1,13 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>FOCUS default values for soil moisture contents at field capacity, MWHC and 1/3 bar — focus_soil_moisture • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="FOCUS default values for soil moisture contents at field capacity, MWHC and 1/3 bar — focus_soil_moisture" /> -<meta property="og:description" content="The value were transcribed from p. 36. The table assumes field capacity -corresponds to pF2, MWHC to pF 1 and 1/3 bar to pF 2.5." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>FOCUS default values for soil moisture contents at field capacity, MWHC and 1/3 bar — focus_soil_moisture • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="FOCUS default values for soil moisture contents at field capacity, MWHC and 1/3 bar — focus_soil_moisture"><meta property="og:description" content="The value were transcribed from p. 36. The table assumes field capacity +corresponds to pF2, MWHC to pF 1 and 1/3 bar to pF 2.5."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -73,13 +18,12 @@ corresponds to pF2, MWHC to pF 1 and 1/3 bar to pF 2.5." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -88,8 +32,7 @@ corresponds to pF2, MWHC to pF 1 and 1/3 bar to pF 2.5." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -99,6 +42,9 @@ corresponds to pF2, MWHC to pF 1 and 1/3 bar to pF 2.5." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -113,34 +59,27 @@ corresponds to pF2, MWHC to pF 1 and 1/3 bar to pF 2.5." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>FOCUS default values for soil moisture contents at field capacity, MWHC and 1/3 bar</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/focus_soil_moisture.R'><code>R/focus_soil_moisture.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/focus_soil_moisture.R" class="external-link"><code>R/focus_soil_moisture.R</code></a></small> <div class="hidden name"><code>focus_soil_moisture.Rd</code></div> </div> @@ -149,58 +88,60 @@ corresponds to pF2, MWHC to pF 1 and 1/3 bar to pF 2.5." /> corresponds to pF2, MWHC to pF 1 and 1/3 bar to pF 2.5.</p> </div> - <pre class="usage"><span class='va'>focus_soil_moisture</span></pre> - - - <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="va">focus_soil_moisture</span></code></pre></div> + </div> + <div id="format"> + <h2>Format</h2> <p>A matrix with upper case USDA soil classes as row names, and water tension ('pF1', 'pF2', 'pF 2.5') as column names</p> - <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2> - + </div> + <div id="source"> + <h2>Source</h2> <p>Anonymous (2014) Generic Guidance for Tier 1 FOCUS Ground Water Assessment -Version 2.2, May 2014 <a href='https://esdac.jrc.ec.europa.eu/projects/ground-water'>https://esdac.jrc.ec.europa.eu/projects/ground-water</a></p> - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='va'>focus_soil_moisture</span> -</div><div class='output co'>#> pF1 pF2 pF2.5 -#> Sand 24 12 7 -#> Loamy sand 24 14 9 -#> Sandy loam 27 19 15 -#> Sandy clay loam 28 22 18 -#> Clay loam 32 28 25 -#> Loam 31 25 21 -#> Silt loam 32 26 21 -#> Silty clay loam 34 30 27 -#> Silt 31 27 21 -#> Sandy clay 41 35 31 -#> Silty clay 44 40 36 -#> Clay 53 48 43</div></pre> +Version 2.2, May 2014 <a href="https://esdac.jrc.ec.europa.eu/projects/ground-water" class="external-link">https://esdac.jrc.ec.europa.eu/projects/ground-water</a></p> + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="va">focus_soil_moisture</span></span> +<span class="r-out co"><span class="r-pr">#></span> pF1 pF2 pF2.5</span> +<span class="r-out co"><span class="r-pr">#></span> Sand 24 12 7</span> +<span class="r-out co"><span class="r-pr">#></span> Loamy sand 24 14 9</span> +<span class="r-out co"><span class="r-pr">#></span> Sandy loam 27 19 15</span> +<span class="r-out co"><span class="r-pr">#></span> Sandy clay loam 28 22 18</span> +<span class="r-out co"><span class="r-pr">#></span> Clay loam 32 28 25</span> +<span class="r-out co"><span class="r-pr">#></span> Loam 31 25 21</span> +<span class="r-out co"><span class="r-pr">#></span> Silt loam 32 26 21</span> +<span class="r-out co"><span class="r-pr">#></span> Silty clay loam 34 30 27</span> +<span class="r-out co"><span class="r-pr">#></span> Silt 31 27 21</span> +<span class="r-out co"><span class="r-pr">#></span> Sandy clay 41 35 31</span> +<span class="r-out co"><span class="r-pr">#></span> Silty clay 44 40 36</span> +<span class="r-out co"><span class="r-pr">#></span> Clay 53 48 43</span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/get_deg_func.html b/docs/reference/get_deg_func.html index 44703806..55d325f5 100644 --- a/docs/reference/get_deg_func.html +++ b/docs/reference/get_deg_func.html @@ -1,67 +1,12 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Retrieve a degradation function from the mmkin namespace — get_deg_func • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Retrieve a degradation function from the mmkin namespace — get_deg_func" /> -<meta property="og:description" content="Retrieve a degradation function from the mmkin namespace" /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Retrieve a degradation function from the mmkin namespace — get_deg_func • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Retrieve a degradation function from the mmkin namespace — get_deg_func"><meta property="og:description" content="Retrieve a degradation function from the mmkin namespace"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -72,13 +17,12 @@ </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -87,8 +31,7 @@ <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -98,6 +41,9 @@ <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -112,34 +58,27 @@ <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Retrieve a degradation function from the mmkin namespace</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/nlme.mmkin.R'><code>R/nlme.mmkin.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/nlme.mmkin.R" class="external-link"><code>R/nlme.mmkin.R</code></a></small> <div class="hidden name"><code>get_deg_func.Rd</code></div> </div> @@ -147,39 +86,37 @@ <p>Retrieve a degradation function from the mmkin namespace</p> </div> - <pre class="usage"><span class='fu'>get_deg_func</span><span class='op'>(</span><span class='op'>)</span></pre> - - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">get_deg_func</span><span class="op">(</span><span class="op">)</span></code></pre></div> + </div> + <div id="value"> + <h2>Value</h2> <p>A function that was likely previously assigned from within nlme.mmkin</p> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/ilr.html b/docs/reference/ilr.html index 671faf5d..5322c41e 100644 --- a/docs/reference/ilr.html +++ b/docs/reference/ilr.html @@ -1,68 +1,13 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Function to perform isometric log-ratio transformation — ilr • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Function to perform isometric log-ratio transformation — ilr" /> -<meta property="og:description" content="This implementation is a special case of the class of isometric log-ratio -transformations." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Function to perform isometric log-ratio transformation — ilr • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Function to perform isometric log-ratio transformation — ilr"><meta property="og:description" content="This implementation is a special case of the class of isometric log-ratio +transformations."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -73,13 +18,12 @@ transformations." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -88,8 +32,7 @@ transformations." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -99,6 +42,9 @@ transformations." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -113,34 +59,27 @@ transformations." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Function to perform isometric log-ratio transformation</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/ilr.R'><code>R/ilr.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/ilr.R" class="external-link"><code>R/ilr.R</code></a></small> <div class="hidden name"><code>ilr.Rd</code></div> </div> @@ -149,86 +88,97 @@ transformations." /> transformations.</p> </div> - <pre class="usage"><span class='fu'>ilr</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> - -<span class='fu'>invilr</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">ilr</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>x</th> - <td><p>A numeric vector. Naturally, the forward transformation is only -sensible for vectors with all elements being greater than zero.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> +<span class="fu">invilr</span><span class="op">(</span><span class="va">x</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>x</dt> +<dd><p>A numeric vector. Naturally, the forward transformation is only +sensible for vectors with all elements being greater than zero.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The result of the forward or backward transformation. The returned components always sum to 1 for the case of the inverse log-ratio transformation.</p> - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - + </div> + <div id="references"> + <h2>References</h2> <p>Peter Filzmoser, Karel Hron (2008) Outlier Detection for Compositional Data Using Robust Methods. Math Geosci 40 233-248</p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p>Another implementation can be found in R package + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p>Another implementation can be found in R package <code>robCompositions</code>.</p></div> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="author"> + <h2>Author</h2> <p>René Lehmann and Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='co'># Order matters</span> -<span class='fu'>ilr</span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0.1</span>, <span class='fl'>1</span>, <span class='fl'>10</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> [1] -1.628174 -2.820079</div><div class='input'><span class='fu'>ilr</span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>10</span>, <span class='fl'>1</span>, <span class='fl'>0.1</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> [1] 1.628174 2.820079</div><div class='input'><span class='co'># Equal entries give ilr transformations with zeros as elements</span> -<span class='fu'>ilr</span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>3</span>, <span class='fl'>3</span>, <span class='fl'>3</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> [1] 0 0</div><div class='input'><span class='co'># Almost equal entries give small numbers</span> -<span class='fu'>ilr</span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0.3</span>, <span class='fl'>0.4</span>, <span class='fl'>0.3</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> [1] -0.2034219 0.1174457</div><div class='input'><span class='co'># Only the ratio between the numbers counts, not their sum</span> -<span class='fu'>invilr</span><span class='op'>(</span><span class='fu'>ilr</span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0.7</span>, <span class='fl'>0.29</span>, <span class='fl'>0.01</span><span class='op'>)</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> [1] 0.70 0.29 0.01</div><div class='input'><span class='fu'>invilr</span><span class='op'>(</span><span class='fu'>ilr</span><span class='op'>(</span><span class='fl'>2.1</span> <span class='op'>*</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0.7</span>, <span class='fl'>0.29</span>, <span class='fl'>0.01</span><span class='op'>)</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> [1] 0.70 0.29 0.01</div><div class='input'><span class='co'># Inverse transformation of larger numbers gives unequal elements</span> -<span class='fu'>invilr</span><span class='op'>(</span><span class='op'>-</span><span class='fl'>10</span><span class='op'>)</span> -</div><div class='output co'>#> [1] 7.213536e-07 9.999993e-01</div><div class='input'><span class='fu'>invilr</span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='op'>-</span><span class='fl'>10</span>, <span class='fl'>0</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> [1] 7.207415e-07 9.991507e-01 8.486044e-04</div><div class='input'><span class='co'># The sum of the elements of the inverse ilr is 1</span> -<span class='fu'><a href='https://rdrr.io/r/base/sum.html'>sum</a></span><span class='op'>(</span><span class='fu'>invilr</span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='op'>-</span><span class='fl'>10</span>, <span class='fl'>0</span><span class='op'>)</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> [1] 1</div><div class='input'><span class='co'># This is why we do not need all elements of the inverse transformation to go back:</span> -<span class='va'>a</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0.1</span>, <span class='fl'>0.3</span>, <span class='fl'>0.5</span><span class='op'>)</span> -<span class='va'>b</span> <span class='op'><-</span> <span class='fu'>invilr</span><span class='op'>(</span><span class='va'>a</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/length.html'>length</a></span><span class='op'>(</span><span class='va'>b</span><span class='op'>)</span> <span class='co'># Four elements</span> -</div><div class='output co'>#> [1] 4</div><div class='input'><span class='fu'>ilr</span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='va'>b</span><span class='op'>[</span><span class='fl'>1</span><span class='op'>:</span><span class='fl'>3</span><span class='op'>]</span>, <span class='fl'>1</span> <span class='op'>-</span> <span class='fu'><a href='https://rdrr.io/r/base/sum.html'>sum</a></span><span class='op'>(</span><span class='va'>b</span><span class='op'>[</span><span class='fl'>1</span><span class='op'>:</span><span class='fl'>3</span><span class='op'>]</span><span class='op'>)</span><span class='op'>)</span><span class='op'>)</span> <span class='co'># Gives c(0.1, 0.3, 0.5)</span> -</div><div class='output co'>#> [1] 0.1 0.3 0.5</div><div class='input'> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="co"># Order matters</span></span> +<span class="r-in"><span class="fu">ilr</span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0.1</span>, <span class="fl">1</span>, <span class="fl">10</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] -1.628174 -2.820079</span> +<span class="r-in"><span class="fu">ilr</span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">10</span>, <span class="fl">1</span>, <span class="fl">0.1</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 1.628174 2.820079</span> +<span class="r-in"><span class="co"># Equal entries give ilr transformations with zeros as elements</span></span> +<span class="r-in"><span class="fu">ilr</span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">3</span>, <span class="fl">3</span>, <span class="fl">3</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 0 0</span> +<span class="r-in"><span class="co"># Almost equal entries give small numbers</span></span> +<span class="r-in"><span class="fu">ilr</span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0.3</span>, <span class="fl">0.4</span>, <span class="fl">0.3</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] -0.2034219 0.1174457</span> +<span class="r-in"><span class="co"># Only the ratio between the numbers counts, not their sum</span></span> +<span class="r-in"><span class="fu">invilr</span><span class="op">(</span><span class="fu">ilr</span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0.7</span>, <span class="fl">0.29</span>, <span class="fl">0.01</span><span class="op">)</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 0.70 0.29 0.01</span> +<span class="r-in"><span class="fu">invilr</span><span class="op">(</span><span class="fu">ilr</span><span class="op">(</span><span class="fl">2.1</span> <span class="op">*</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0.7</span>, <span class="fl">0.29</span>, <span class="fl">0.01</span><span class="op">)</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 0.70 0.29 0.01</span> +<span class="r-in"><span class="co"># Inverse transformation of larger numbers gives unequal elements</span></span> +<span class="r-in"><span class="fu">invilr</span><span class="op">(</span><span class="op">-</span><span class="fl">10</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 7.213536e-07 9.999993e-01</span> +<span class="r-in"><span class="fu">invilr</span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="op">-</span><span class="fl">10</span>, <span class="fl">0</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 7.207415e-07 9.991507e-01 8.486044e-04</span> +<span class="r-in"><span class="co"># The sum of the elements of the inverse ilr is 1</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/sum.html" class="external-link">sum</a></span><span class="op">(</span><span class="fu">invilr</span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="op">-</span><span class="fl">10</span>, <span class="fl">0</span><span class="op">)</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 1</span> +<span class="r-in"><span class="co"># This is why we do not need all elements of the inverse transformation to go back:</span></span> +<span class="r-in"><span class="va">a</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0.1</span>, <span class="fl">0.3</span>, <span class="fl">0.5</span><span class="op">)</span></span> +<span class="r-in"><span class="va">b</span> <span class="op"><-</span> <span class="fu">invilr</span><span class="op">(</span><span class="va">a</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/length.html" class="external-link">length</a></span><span class="op">(</span><span class="va">b</span><span class="op">)</span> <span class="co"># Four elements</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 4</span> +<span class="r-in"><span class="fu">ilr</span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="va">b</span><span class="op">[</span><span class="fl">1</span><span class="op">:</span><span class="fl">3</span><span class="op">]</span>, <span class="fl">1</span> <span class="op">-</span> <span class="fu"><a href="https://rdrr.io/r/base/sum.html" class="external-link">sum</a></span><span class="op">(</span><span class="va">b</span><span class="op">[</span><span class="fl">1</span><span class="op">:</span><span class="fl">3</span><span class="op">]</span><span class="op">)</span><span class="op">)</span><span class="op">)</span> <span class="co"># Gives c(0.1, 0.3, 0.5)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 0.1 0.3 0.5</span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/index.html b/docs/reference/index.html index ff7a4198..552829bf 100644 --- a/docs/reference/index.html +++ b/docs/reference/index.html @@ -1,66 +1,12 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Function reference • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Function reference" /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Function reference • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Function reference"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-index"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -71,13 +17,12 @@ </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.5</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -86,8 +31,7 @@ <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -97,6 +41,9 @@ <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -111,620 +58,402 @@ <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="contents col-md-9"> <div class="page-header"> <h1>Reference</h1> </div> - <table class="ref-index"> - - <colgroup> - - <col class="alias" /> - <col class="title" /> - </colgroup> - - <tbody> - <tr> - <th colspan="2"> - <h2 id="section-main-functions" class="hasAnchor"><a href="#section-main-functions" class="anchor"></a>Main functions</h2> - <p class="section-desc"><p>Essential functionality</p></p> + <table class="ref-index"><colgroup><col class="alias"><col class="title"></colgroup><tbody><tr><th colspan="2"> + <h2 id="main-functions">Main functions <a href="#main-functions" class="anchor" aria-hidden="true"></a></h2> + <p class="section-desc"></p><p>Essential functionality</p> </th> - </tr> - - - </tbody><tbody> - - - <tr> - - <td> + </tr></tbody><tbody><tr><td> <p><code><a href="mkinmod.html">mkinmod()</a></code> <code><a href="mkinmod.html">print(<i><mkinmod></i>)</a></code> <code><a href="mkinmod.html">mkinsub()</a></code> </p> </td> <td><p>Function to set up a kinetic model with one or more state variables</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="mkinfit.html">mkinfit()</a></code> </p> </td> <td><p>Fit a kinetic model to data with one or more state variables</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="mmkin.html">mmkin()</a></code> <code><a href="mmkin.html">print(<i><mmkin></i>)</a></code> </p> </td> <td><p>Fit one or more kinetic models with one or more state variables to one or more datasets</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="nafta.html">nafta()</a></code> <code><a href="nafta.html">print(<i><nafta></i>)</a></code> </p> </td> <td><p>Evaluate parent kinetics using the NAFTA guidance</p></td> - </tr> - </tbody><tbody> - <tr> - <th colspan="2"> - <h2 id="section-show-results" class="hasAnchor"><a href="#section-show-results" class="anchor"></a>Show results</h2> - <p class="section-desc"><p>Functions working with mkinfit objects</p></p> + </tr></tbody><tbody><tr><th colspan="2"> + <h2 id="show-results">Show results <a href="#show-results" class="anchor" aria-hidden="true"></a></h2> + <p class="section-desc"></p><p>Functions working with mkinfit objects</p> </th> - </tr> - - - </tbody><tbody> - - - <tr> - - <td> + </tr></tbody><tbody><tr><td> <p><code><a href="plot.mkinfit.html">plot(<i><mkinfit></i>)</a></code> <code><a href="plot.mkinfit.html">plot_sep()</a></code> <code><a href="plot.mkinfit.html">plot_res()</a></code> <code><a href="plot.mkinfit.html">plot_err()</a></code> </p> </td> <td><p>Plot the observed data and the fitted model of an mkinfit object</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="summary.mkinfit.html">summary(<i><mkinfit></i>)</a></code> <code><a href="summary.mkinfit.html">print(<i><summary.mkinfit></i>)</a></code> </p> </td> <td><p>Summary method for class "mkinfit"</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="parms.html">parms()</a></code> </p> </td> <td><p>Extract model parameters from mkinfit models</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="confint.mkinfit.html">confint(<i><mkinfit></i>)</a></code> </p> </td> <td><p>Confidence intervals for parameters of mkinfit objects</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="update.mkinfit.html">update(<i><mkinfit></i>)</a></code> </p> </td> <td><p>Update an mkinfit model with different arguments</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="lrtest.mkinfit.html">lrtest(<i><mkinfit></i>)</a></code> <code><a href="lrtest.mkinfit.html">lrtest(<i><mmkin></i>)</a></code> </p> </td> <td><p>Likelihood ratio test for mkinfit models</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="loftest.html">loftest()</a></code> </p> </td> <td><p>Lack-of-fit test for models fitted to data with replicates</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="mkinerrmin.html">mkinerrmin()</a></code> </p> </td> <td><p>Calculate the minimum error to assume in order to pass the variance test</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="endpoints.html">endpoints()</a></code> </p> </td> <td><p>Function to calculate endpoints for further use from kinetic models fitted with mkinfit</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="aw.html">aw()</a></code> </p> </td> <td><p>Calculate Akaike weights for model averaging</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="CAKE_export.html">CAKE_export()</a></code> </p> </td> <td><p>Export a list of datasets format to a CAKE study file</p></td> - </tr> - </tbody><tbody> - <tr> - <th colspan="2"> - <h2 id="section-work-with-mmkin-objects" class="hasAnchor"><a href="#section-work-with-mmkin-objects" class="anchor"></a>Work with mmkin objects</h2> - <p class="section-desc"><p>Functions working with aggregated results</p></p> + </tr></tbody><tbody><tr><th colspan="2"> + <h2 id="work-with-mmkin-objects">Work with mmkin objects <a href="#work-with-mmkin-objects" class="anchor" aria-hidden="true"></a></h2> + <p class="section-desc"></p><p>Functions working with aggregated results</p> </th> - </tr> - - - </tbody><tbody> - - - <tr> - - <td> + </tr></tbody><tbody><tr><td> <p><code><a href="Extract.mmkin.html">`[`(<i><mmkin></i>)</a></code> </p> </td> <td><p>Subsetting method for mmkin objects</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="plot.mmkin.html">plot(<i><mmkin></i>)</a></code> </p> </td> <td><p>Plot model fits (observed and fitted) and the residuals for a row or column of an mmkin object</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="AIC.mmkin.html">AIC(<i><mmkin></i>)</a></code> <code><a href="AIC.mmkin.html">BIC(<i><mmkin></i>)</a></code> </p> </td> <td><p>Calculate the AIC for a column of an mmkin object</p></td> - </tr> - </tbody><tbody> - <tr> - <th colspan="2"> - <h2 id="section-mixed-models" class="hasAnchor"><a href="#section-mixed-models" class="anchor"></a>Mixed models</h2> - <p class="section-desc"><p>Create and work with nonlinear mixed effects models</p></p> + </tr></tbody><tbody><tr><th colspan="2"> + <h2 id="mixed-models">Mixed models <a href="#mixed-models" class="anchor" aria-hidden="true"></a></h2> + <p class="section-desc"></p><p>Create and work with nonlinear mixed effects models</p> </th> - </tr> - - - </tbody><tbody> - - - <tr> - - <td> + </tr></tbody><tbody><tr><td> <p><code><a href="nlme.mmkin.html">nlme(<i><mmkin></i>)</a></code> <code><a href="nlme.mmkin.html">print(<i><nlme.mmkin></i>)</a></code> <code><a href="nlme.mmkin.html">update(<i><nlme.mmkin></i>)</a></code> </p> </td> <td><p>Create an nlme model for an mmkin row object</p></td> - </tr><tr> - - <td> + </tr><tr><td> + <p><code><a href="saem.html">saem()</a></code> <code><a href="saem.html">print(<i><saem.mmkin></i>)</a></code> <code><a href="saem.html">saemix_model()</a></code> <code><a href="saem.html">saemix_data()</a></code> </p> + </td> + <td><p>Fit nonlinear mixed models with SAEM</p></td> + </tr><tr><td> + <p><code><a href="nlmixr.mmkin.html">nlmixr(<i><mmkin></i>)</a></code> <code><a href="nlmixr.mmkin.html">print(<i><nlmixr.mmkin></i>)</a></code> <code><a href="nlmixr.mmkin.html">nlmixr_model()</a></code> <code><a href="nlmixr.mmkin.html">nlmixr_data()</a></code> </p> + </td> + <td><p>Fit nonlinear mixed models using nlmixr</p></td> + </tr><tr><td> <p><code><a href="plot.mixed.mmkin.html">plot(<i><mixed.mmkin></i>)</a></code> </p> </td> <td><p>Plot predictions from a fitted nonlinear mixed model obtained via an mmkin row object</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="summary.nlme.mmkin.html">summary(<i><nlme.mmkin></i>)</a></code> <code><a href="summary.nlme.mmkin.html">print(<i><summary.nlme.mmkin></i>)</a></code> </p> </td> <td><p>Summary method for class "nlme.mmkin"</p></td> - </tr><tr> - - <td> - <p><code><a href="nlme.html">nlme_function()</a></code> <code><a href="nlme.html">mean_degparms()</a></code> <code><a href="nlme.html">nlme_data()</a></code> </p> + </tr><tr><td> + <p><code><a href="summary.nlmixr.mmkin.html">summary(<i><nlmixr.mmkin></i>)</a></code> <code><a href="summary.nlmixr.mmkin.html">print(<i><summary.nlmixr.mmkin></i>)</a></code> </p> + </td> + <td><p>Summary method for class "nlmixr.mmkin"</p></td> + </tr><tr><td> + <p><code><a href="summary.saem.mmkin.html">summary(<i><saem.mmkin></i>)</a></code> <code><a href="summary.saem.mmkin.html">print(<i><summary.saem.mmkin></i>)</a></code> </p> + </td> + <td><p>Summary method for class "saem.mmkin"</p></td> + </tr><tr><td> + <p><code><a href="nlme.html">nlme_function()</a></code> <code><a href="nlme.html">nlme_data()</a></code> </p> </td> <td><p>Helper functions to create nlme models from mmkin row objects</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="get_deg_func.html">get_deg_func()</a></code> </p> </td> <td><p>Retrieve a degradation function from the mmkin namespace</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="mixed.html">mixed()</a></code> <code><a href="mixed.html">print(<i><mixed.mmkin></i>)</a></code> </p> </td> <td><p>Create a mixed effects model from an mmkin row object</p></td> - </tr> - </tbody><tbody> - <tr> - <th colspan="2"> - <h2 id="section-datasets-and-known-results" class="hasAnchor"><a href="#section-datasets-and-known-results" class="anchor"></a>Datasets and known results</h2> + </tr><tr><td> + <p><code><a href="reexports.html">reexports</a></code> </p> + </td> + <td><p>Objects exported from other packages</p></td> + </tr><tr><td> + <p><code><a href="intervals.saem.mmkin.html">intervals(<i><saem.mmkin></i>)</a></code> </p> + </td> + <td><p>Confidence intervals for parameters in saem.mmkin objects</p></td> + </tr><tr><td> + <p><code><a href="intervals.nlmixr.mmkin.html">intervals(<i><nlmixr.mmkin></i>)</a></code> </p> + </td> + <td><p>Confidence intervals for parameters in nlmixr.mmkin objects</p></td> + </tr></tbody><tbody><tr><th colspan="2"> + <h2 id="datasets-and-known-results">Datasets and known results <a href="#datasets-and-known-results" class="anchor" aria-hidden="true"></a></h2> <p class="section-desc"></p> </th> - </tr> - - - </tbody><tbody> - - - <tr> - - <td> + </tr></tbody><tbody><tr><td> <p><code><a href="focus_soil_moisture.html">focus_soil_moisture</a></code> </p> </td> <td><p>FOCUS default values for soil moisture contents at field capacity, MWHC and 1/3 bar</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="D24_2014.html">D24_2014</a></code> </p> </td> <td><p>Aerobic soil degradation data on 2,4-D from the EU assessment in 2014</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="dimethenamid_2018.html">dimethenamid_2018</a></code> </p> </td> <td><p>Aerobic soil degradation data on dimethenamid and dimethenamid-P from the EU assessment in 2018</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="FOCUS_2006_datasets.html">FOCUS_2006_A</a></code> <code><a href="FOCUS_2006_datasets.html">FOCUS_2006_B</a></code> <code><a href="FOCUS_2006_datasets.html">FOCUS_2006_C</a></code> <code><a href="FOCUS_2006_datasets.html">FOCUS_2006_D</a></code> <code><a href="FOCUS_2006_datasets.html">FOCUS_2006_E</a></code> <code><a href="FOCUS_2006_datasets.html">FOCUS_2006_F</a></code> </p> </td> <td><p>Datasets A to F from the FOCUS Kinetics report from 2006</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="FOCUS_2006_SFO_ref_A_to_F.html">FOCUS_2006_SFO_ref_A_to_F</a></code> </p> </td> <td><p>Results of fitting the SFO model to Datasets A to F of FOCUS (2006)</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="FOCUS_2006_FOMC_ref_A_to_F.html">FOCUS_2006_FOMC_ref_A_to_F</a></code> </p> </td> <td><p>Results of fitting the FOMC model to Datasets A to F of FOCUS (2006)</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="FOCUS_2006_HS_ref_A_to_F.html">FOCUS_2006_HS_ref_A_to_F</a></code> </p> </td> <td><p>Results of fitting the HS model to Datasets A to F of FOCUS (2006)</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="FOCUS_2006_DFOP_ref_A_to_B.html">FOCUS_2006_DFOP_ref_A_to_B</a></code> </p> </td> <td><p>Results of fitting the DFOP model to Datasets A to B of FOCUS (2006)</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="NAFTA_SOP_2015.html">NAFTA_SOP_Appendix_B</a></code> <code><a href="NAFTA_SOP_2015.html">NAFTA_SOP_Appendix_D</a></code> </p> </td> <td><p>Example datasets from the NAFTA SOP published 2015</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="NAFTA_SOP_Attachment.html">NAFTA_SOP_Attachment</a></code> </p> </td> <td><p>Example datasets from Attachment 1 to the NAFTA SOP published 2015</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="mccall81_245T.html">mccall81_245T</a></code> </p> </td> <td><p>Datasets on aerobic soil metabolism of 2,4,5-T in six soils</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="schaefer07_complex_case.html">schaefer07_complex_case</a></code> </p> </td> <td><p>Metabolism data set used for checking the software quality of KinGUI</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="synthetic_data_for_UBA_2014.html">synthetic_data_for_UBA_2014</a></code> </p> </td> <td><p>Synthetic datasets for one parent compound with two metabolites</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="experimental_data_for_UBA.html">experimental_data_for_UBA_2019</a></code> </p> </td> <td><p>Experimental datasets used for development and testing of error models</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="test_data_from_UBA_2014.html">test_data_from_UBA_2014</a></code> </p> </td> <td><p>Three experimental datasets from two water sediment systems and one soil</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="mkinds.html">print(<i><mkinds></i>)</a></code> </p> </td> <td><p>A dataset class for mkin</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="mkindsg.html">print(<i><mkindsg></i>)</a></code> </p> </td> <td><p>A class for dataset groups for mkin</p></td> - </tr> - </tbody><tbody> - <tr> - <th colspan="2"> - <h2 id="section-nafta-guidance" class="hasAnchor"><a href="#section-nafta-guidance" class="anchor"></a>NAFTA guidance</h2> + </tr></tbody><tbody><tr><th colspan="2"> + <h2 id="nafta-guidance">NAFTA guidance <a href="#nafta-guidance" class="anchor" aria-hidden="true"></a></h2> <p class="section-desc"></p> </th> - </tr> - - - </tbody><tbody> - - - <tr> - - <td> + </tr></tbody><tbody><tr><td> <p><code><a href="nafta.html">nafta()</a></code> <code><a href="nafta.html">print(<i><nafta></i>)</a></code> </p> </td> <td><p>Evaluate parent kinetics using the NAFTA guidance</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="plot.nafta.html">plot(<i><nafta></i>)</a></code> </p> </td> <td><p>Plot the results of the three models used in the NAFTA scheme.</p></td> - </tr> - </tbody><tbody> - <tr> - <th colspan="2"> - <h2 id="section-utility-functions" class="hasAnchor"><a href="#section-utility-functions" class="anchor"></a>Utility functions</h2> + </tr></tbody><tbody><tr><th colspan="2"> + <h2 id="utility-functions">Utility functions <a href="#utility-functions" class="anchor" aria-hidden="true"></a></h2> <p class="section-desc"></p> </th> - </tr> - - - </tbody><tbody> - - - <tr> - - <td> + </tr></tbody><tbody><tr><td> <p><code><a href="f_time_norm_focus.html">f_time_norm_focus()</a></code> </p> </td> <td><p>Normalisation factors for aerobic soil degradation according to FOCUS guidance</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="max_twa_parent.html">max_twa_parent()</a></code> <code><a href="max_twa_parent.html">max_twa_sfo()</a></code> <code><a href="max_twa_parent.html">max_twa_fomc()</a></code> <code><a href="max_twa_parent.html">max_twa_dfop()</a></code> <code><a href="max_twa_parent.html">max_twa_hs()</a></code> </p> </td> <td><p>Function to calculate maximum time weighted average concentrations from kinetic models fitted with mkinfit</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="mkin_wide_to_long.html">mkin_wide_to_long()</a></code> </p> </td> <td><p>Convert a dataframe with observations over time into long format</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="mkin_long_to_wide.html">mkin_long_to_wide()</a></code> </p> </td> <td><p>Convert a dataframe from long to wide format</p></td> - </tr> - </tbody><tbody> - <tr> - <th colspan="2"> - <h2 id="section-helper-functions-mainly-used-internally" class="hasAnchor"><a href="#section-helper-functions-mainly-used-internally" class="anchor"></a>Helper functions mainly used internally</h2> + </tr></tbody><tbody><tr><th colspan="2"> + <h2 id="helper-functions-mainly-used-internally">Helper functions mainly used internally <a href="#helper-functions-mainly-used-internally" class="anchor" aria-hidden="true"></a></h2> <p class="section-desc"></p> </th> - </tr> - - - </tbody><tbody> - - - <tr> - - <td> + </tr></tbody><tbody><tr><td> <p><code><a href="mkinpredict.html">mkinpredict()</a></code> </p> </td> <td><p>Produce predictions from a kinetic model using specific parameters</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="transform_odeparms.html">transform_odeparms()</a></code> <code><a href="transform_odeparms.html">backtransform_odeparms()</a></code> </p> </td> <td><p>Functions to transform and backtransform kinetic parameters for fitting</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="ilr.html">ilr()</a></code> <code><a href="ilr.html">invilr()</a></code> </p> </td> <td><p>Function to perform isometric log-ratio transformation</p></td> - </tr><tr> - - <td> + </tr><tr><td> + <p><code><a href="tffm0.html">tffm0()</a></code> <code><a href="tffm0.html">invtffm0()</a></code> </p> + </td> + <td><p>Transform formation fractions as in the first published mkin version</p></td> + </tr><tr><td> <p><code><a href="logLik.mkinfit.html">logLik(<i><mkinfit></i>)</a></code> </p> </td> <td><p>Calculated the log-likelihood of a fitted mkinfit object</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="residuals.mkinfit.html">residuals(<i><mkinfit></i>)</a></code> </p> </td> <td><p>Extract residuals from an mkinfit model</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="nobs.mkinfit.html">nobs(<i><mkinfit></i>)</a></code> </p> </td> <td><p>Number of observations on which an mkinfit object was fitted</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="mkinresplot.html">mkinresplot()</a></code> </p> </td> <td><p>Function to plot residuals stored in an mkin object</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="mkinparplot.html">mkinparplot()</a></code> </p> </td> <td><p>Function to plot the confidence intervals obtained using mkinfit</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="mkinerrplot.html">mkinerrplot()</a></code> </p> </td> <td><p>Function to plot squared residuals and the error model for an mkin object</p></td> - </tr><tr> - - <td> + </tr><tr><td> + <p><code><a href="mean_degparms.html">mean_degparms()</a></code> </p> + </td> + <td><p>Calculate mean degradation parameters for an mmkin row object</p></td> + </tr><tr><td> <p><code><a href="create_deg_func.html">create_deg_func()</a></code> </p> </td> <td><p>Create degradation functions for known analytical solutions</p></td> - </tr> - </tbody><tbody> - <tr> - <th colspan="2"> - <h2 id="section-analytical-solutions" class="hasAnchor"><a href="#section-analytical-solutions" class="anchor"></a>Analytical solutions</h2> - <p class="section-desc"><p>Parent only model solutions</p></p> + </tr></tbody><tbody><tr><th colspan="2"> + <h2 id="analytical-solutions">Analytical solutions <a href="#analytical-solutions" class="anchor" aria-hidden="true"></a></h2> + <p class="section-desc"></p><p>Parent only model solutions</p> </th> - </tr> - - - </tbody><tbody> - - - <tr> - - <td> + </tr></tbody><tbody><tr><td> <p><code><a href="SFO.solution.html">SFO.solution()</a></code> </p> </td> <td><p>Single First-Order kinetics</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="FOMC.solution.html">FOMC.solution()</a></code> </p> </td> <td><p>First-Order Multi-Compartment kinetics</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="DFOP.solution.html">DFOP.solution()</a></code> </p> </td> <td><p>Double First-Order in Parallel kinetics</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="SFORB.solution.html">SFORB.solution()</a></code> </p> </td> <td><p>Single First-Order Reversible Binding kinetics</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="HS.solution.html">HS.solution()</a></code> </p> </td> <td><p>Hockey-Stick kinetics</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="IORE.solution.html">IORE.solution()</a></code> </p> </td> <td><p>Indeterminate order rate equation kinetics</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="logistic.solution.html">logistic.solution()</a></code> </p> </td> <td><p>Logistic kinetics</p></td> - </tr> - </tbody><tbody> - <tr> - <th colspan="2"> - <h2 id="section-generate-synthetic-datasets" class="hasAnchor"><a href="#section-generate-synthetic-datasets" class="anchor"></a>Generate synthetic datasets</h2> + </tr></tbody><tbody><tr><th colspan="2"> + <h2 id="generate-synthetic-datasets">Generate synthetic datasets <a href="#generate-synthetic-datasets" class="anchor" aria-hidden="true"></a></h2> <p class="section-desc"></p> </th> - </tr> - - - </tbody><tbody> - - - <tr> - - <td> + </tr></tbody><tbody><tr><td> <p><code><a href="add_err.html">add_err()</a></code> </p> </td> <td><p>Add normally distributed errors to simulated kinetic degradation data</p></td> - </tr><tr> - - <td> + </tr><tr><td> <p><code><a href="sigma_twocomp.html">sigma_twocomp()</a></code> </p> </td> <td><p>Two-component error model</p></td> - </tr> - </tbody><tbody> - <tr> - <th colspan="2"> - <h2 id="section-deprecated-functions" class="hasAnchor"><a href="#section-deprecated-functions" class="anchor"></a>Deprecated functions</h2> - <p class="section-desc"><p>Functions that have been superseded</p></p> + </tr></tbody><tbody><tr><th colspan="2"> + <h2 id="deprecated-functions">Deprecated functions <a href="#deprecated-functions" class="anchor" aria-hidden="true"></a></h2> + <p class="section-desc"></p><p>Functions that have been superseded</p> </th> - </tr> - - - </tbody><tbody> - - - <tr> - - <td> + </tr></tbody><tbody><tr><td> <p><code><a href="mkinplot.html">mkinplot()</a></code> </p> </td> <td><p>Plot the observed data and the fitted model of an mkinfit object</p></td> - </tr> - </tbody> - </table> - </div> + </tr></tbody></table></div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/intervals.nlmixr.mmkin.html b/docs/reference/intervals.nlmixr.mmkin.html new file mode 100644 index 00000000..87906c07 --- /dev/null +++ b/docs/reference/intervals.nlmixr.mmkin.html @@ -0,0 +1,135 @@ +<!DOCTYPE html> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Confidence intervals for parameters in nlmixr.mmkin objects — intervals.nlmixr.mmkin • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Confidence intervals for parameters in nlmixr.mmkin objects — intervals.nlmixr.mmkin"><meta property="og:description" content="Confidence intervals for parameters in nlmixr.mmkin objects"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> +<script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> +<script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + + + <div class="container template-reference-topic"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <div class="container"> + <div class="navbar-header"> + <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> + <span class="sr-only">Toggle navigation</span> + <span class="icon-bar"></span> + <span class="icon-bar"></span> + <span class="icon-bar"></span> + </button> + <span class="navbar-brand"> + <a class="navbar-link" href="../index.html">mkin</a> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> + </span> + </div> + + <div id="navbar" class="navbar-collapse collapse"> + <ul class="nav navbar-nav"><li> + <a href="../reference/index.html">Functions and data</a> +</li> +<li class="dropdown"> + <a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-expanded="false"> + Articles + + <span class="caret"></span> + </a> + <ul class="dropdown-menu" role="menu"><li> + <a href="../articles/mkin.html">Introduction to mkin</a> + </li> + <li> + <a href="../articles/FOCUS_D.html">Example evaluation of FOCUS Example Dataset D</a> + </li> + <li> + <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> + </li> + <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> + <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> + </li> + <li> + <a href="../articles/web_only/compiled_models.html">Performance benefit by using compiled model definitions in mkin</a> + </li> + <li> + <a href="../articles/twa.html">Calculation of time weighted average concentrations with mkin</a> + </li> + <li> + <a href="../articles/web_only/NAFTA_examples.html">Example evaluation of NAFTA SOP Attachment examples</a> + </li> + <li> + <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> + </li> + </ul></li> +<li> + <a href="../news/index.html">News</a> +</li> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> + <span class="fab fa-github fa-lg"></span> + + </a> +</li> + </ul></div><!--/.nav-collapse --> + </div><!--/.container --> +</div><!--/.navbar --> + + + + </header><div class="row"> + <div class="col-md-9 contents"> + <div class="page-header"> + <h1>Confidence intervals for parameters in nlmixr.mmkin objects</h1> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/intervals.R" class="external-link"><code>R/intervals.R</code></a></small> + <div class="hidden name"><code>intervals.nlmixr.mmkin.Rd</code></div> + </div> + + <div class="ref-description"> + <p>Confidence intervals for parameters in nlmixr.mmkin objects</p> + </div> + + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for nlmixr.mmkin</span> +<span class="fu"><a href="https://rdrr.io/pkg/nlme/man/intervals.html" class="external-link">intervals</a></span><span class="op">(</span><span class="va">object</span>, level <span class="op">=</span> <span class="fl">0.95</span>, backtransform <span class="op">=</span> <span class="cn">TRUE</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>The fitted saem.mmkin object</p></dd> +<dt>level</dt> +<dd><p>The confidence level.</p></dd> +<dt>backtransform</dt> +<dd><p>Should we backtransform the parameters where a one to +one correlation between transformed and backtransformed parameters exists?</p></dd> +<dt>...</dt> +<dd><p>For compatibility with the generic method</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>An object with 'intervals.saem.mmkin' and 'intervals.lme' in the +class attribute</p> + </div> + + </div> + <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> +</div> + + + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> +</div> + +<div class="pkgdown"> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> +</div> + + </footer></div> + + + + + + + </body></html> + diff --git a/docs/reference/intervals.saem.mmkin.html b/docs/reference/intervals.saem.mmkin.html new file mode 100644 index 00000000..d2eb31de --- /dev/null +++ b/docs/reference/intervals.saem.mmkin.html @@ -0,0 +1,137 @@ +<!DOCTYPE html> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Confidence intervals for parameters in saem.mmkin objects — intervals.saem.mmkin • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Confidence intervals for parameters in saem.mmkin objects — intervals.saem.mmkin"><meta property="og:description" content="Confidence intervals for parameters in saem.mmkin objects"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> +<script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> +<script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + + + <div class="container template-reference-topic"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <div class="container"> + <div class="navbar-header"> + <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> + <span class="sr-only">Toggle navigation</span> + <span class="icon-bar"></span> + <span class="icon-bar"></span> + <span class="icon-bar"></span> + </button> + <span class="navbar-brand"> + <a class="navbar-link" href="../index.html">mkin</a> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> + </span> + </div> + + <div id="navbar" class="navbar-collapse collapse"> + <ul class="nav navbar-nav"><li> + <a href="../reference/index.html">Functions and data</a> +</li> +<li class="dropdown"> + <a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-expanded="false"> + Articles + + <span class="caret"></span> + </a> + <ul class="dropdown-menu" role="menu"><li> + <a href="../articles/mkin.html">Introduction to mkin</a> + </li> + <li> + <a href="../articles/FOCUS_D.html">Example evaluation of FOCUS Example Dataset D</a> + </li> + <li> + <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> + </li> + <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> + <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> + </li> + <li> + <a href="../articles/web_only/compiled_models.html">Performance benefit by using compiled model definitions in mkin</a> + </li> + <li> + <a href="../articles/twa.html">Calculation of time weighted average concentrations with mkin</a> + </li> + <li> + <a href="../articles/web_only/NAFTA_examples.html">Example evaluation of NAFTA SOP Attachment examples</a> + </li> + <li> + <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> + </li> + </ul></li> +<li> + <a href="../news/index.html">News</a> +</li> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> + <span class="fab fa-github fa-lg"></span> + + </a> +</li> + </ul></div><!--/.nav-collapse --> + </div><!--/.container --> +</div><!--/.navbar --> + + + + </header><div class="row"> + <div class="col-md-9 contents"> + <div class="page-header"> + <h1>Confidence intervals for parameters in saem.mmkin objects</h1> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/intervals.R" class="external-link"><code>R/intervals.R</code></a></small> + <div class="hidden name"><code>intervals.saem.mmkin.Rd</code></div> + </div> + + <div class="ref-description"> + <p>Confidence intervals for parameters in saem.mmkin objects</p> + </div> + + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for saem.mmkin</span> +<span class="fu"><a href="https://rdrr.io/pkg/nlme/man/intervals.html" class="external-link">intervals</a></span><span class="op">(</span><span class="va">object</span>, level <span class="op">=</span> <span class="fl">0.95</span>, backtransform <span class="op">=</span> <span class="cn">TRUE</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>The fitted saem.mmkin object</p></dd> +<dt>level</dt> +<dd><p>The confidence level. Must be the default of 0.95 as this is what +is available in the saemix object</p></dd> +<dt>backtransform</dt> +<dd><p>In case the model was fitted with mkin transformations, +should we backtransform the parameters where a one to one correlation +between transformed and backtransformed parameters exists?</p></dd> +<dt>...</dt> +<dd><p>For compatibility with the generic method</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>An object with 'intervals.saem.mmkin' and 'intervals.lme' in the +class attribute</p> + </div> + + </div> + <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> +</div> + + + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> +</div> + +<div class="pkgdown"> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> +</div> + + </footer></div> + + + + + + + </body></html> + diff --git a/docs/reference/loftest-1.png b/docs/reference/loftest-1.png Binary files differindex d6006ecc..f1dc5fa7 100644 --- a/docs/reference/loftest-1.png +++ b/docs/reference/loftest-1.png diff --git a/docs/reference/loftest-2.png b/docs/reference/loftest-2.png Binary files differindex 4d0dc551..3f1015a9 100644 --- a/docs/reference/loftest-2.png +++ b/docs/reference/loftest-2.png diff --git a/docs/reference/loftest-3.png b/docs/reference/loftest-3.png Binary files differindex 6afd084b..d897c363 100644 --- a/docs/reference/loftest-3.png +++ b/docs/reference/loftest-3.png diff --git a/docs/reference/loftest-4.png b/docs/reference/loftest-4.png Binary files differindex f94eede1..ac44c162 100644 --- a/docs/reference/loftest-4.png +++ b/docs/reference/loftest-4.png diff --git a/docs/reference/loftest-5.png b/docs/reference/loftest-5.png Binary files differindex 43460a65..0847bbec 100644 --- a/docs/reference/loftest-5.png +++ b/docs/reference/loftest-5.png diff --git a/docs/reference/loftest.html b/docs/reference/loftest.html index 6e72774e..75578cbe 100644 --- a/docs/reference/loftest.html +++ b/docs/reference/loftest.html @@ -1,70 +1,15 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Lack-of-fit test for models fitted to data with replicates — loftest • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Lack-of-fit test for models fitted to data with replicates — loftest" /> -<meta property="og:description" content="This is a generic function with a method currently only defined for mkinfit +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Lack-of-fit test for models fitted to data with replicates — loftest • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Lack-of-fit test for models fitted to data with replicates — loftest"><meta property="og:description" content="This is a generic function with a method currently only defined for mkinfit objects. It fits an anova model to the data contained in the object and compares the likelihoods using the likelihood ratio test -lrtest.default from the lmtest package." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +lrtest.default from the lmtest package."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -75,13 +20,12 @@ lrtest.default from the lmtest package." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -90,8 +34,7 @@ lrtest.default from the lmtest package." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -101,6 +44,9 @@ lrtest.default from the lmtest package." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -115,34 +61,27 @@ lrtest.default from the lmtest package." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Lack-of-fit test for models fitted to data with replicates</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/loftest.R'><code>R/loftest.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/loftest.R" class="external-link"><code>R/loftest.R</code></a></small> <div class="hidden name"><code>loftest.Rd</code></div> </div> @@ -150,216 +89,228 @@ lrtest.default from the lmtest package." /> <p>This is a generic function with a method currently only defined for mkinfit objects. It fits an anova model to the data contained in the object and compares the likelihoods using the likelihood ratio test -<code><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest.default</a></code> from the lmtest package.</p> +<code><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest.default</a></code> from the lmtest package.</p> </div> - <pre class="usage"><span class='fu'>loftest</span><span class='op'>(</span><span class='va'>object</span>, <span class='va'>...</span><span class='op'>)</span> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">loftest</span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span><span class="op">)</span> -<span class='co'># S3 method for mkinfit</span> -<span class='fu'>loftest</span><span class='op'>(</span><span class='va'>object</span>, <span class='va'>...</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>A model object with a defined loftest method</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Not used</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2> +<span class="co"># S3 method for mkinfit</span> +<span class="fu">loftest</span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>A model object with a defined loftest method</p></dd> +<dt>...</dt> +<dd><p>Not used</p></dd> +</dl></div> + <div id="details"> + <h2>Details</h2> <p>The anova model is interpreted as the simplest form of an mkinfit model, assuming only a constant variance about the means, but not enforcing any structure of the means, so we have one model parameter for every mean of replicate samples.</p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p>lrtest</p></div> + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p>lrtest</p></div> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='co'># \dontrun{</span> -<span class='va'>test_data</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/subset.html'>subset</a></span><span class='op'>(</span><span class='va'>synthetic_data_for_UBA_2014</span><span class='op'>[[</span><span class='fl'>12</span><span class='op'>]</span><span class='op'>]</span><span class='op'>$</span><span class='va'>data</span>, <span class='va'>name</span> <span class='op'>==</span> <span class='st'>"parent"</span><span class='op'>)</span> -<span class='va'>sfo_fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='va'>test_data</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'><a href='plot.mkinfit.html'>plot_res</a></span><span class='op'>(</span><span class='va'>sfo_fit</span><span class='op'>)</span> <span class='co'># We see a clear pattern in the residuals</span> -</div><div class='img'><img src='loftest-1.png' alt='' width='700' height='433' /></div><div class='input'><span class='fu'>loftest</span><span class='op'>(</span><span class='va'>sfo_fit</span><span class='op'>)</span> <span class='co'># We have a clear lack of fit</span> -</div><div class='output co'>#> Likelihood ratio test -#> -#> Model 1: ANOVA with error model const -#> Model 2: SFO with error model const -#> #Df LogLik Df Chisq Pr(>Chisq) -#> 1 10 -40.710 -#> 2 3 -63.954 -7 46.487 7.027e-08 *** -#> --- -#> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</div><div class='input'><span class='co'>#</span> -<span class='co'># We try a different model (the one that was used to generate the data)</span> -<span class='va'>dfop_fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"DFOP"</span>, <span class='va'>test_data</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'><a href='plot.mkinfit.html'>plot_res</a></span><span class='op'>(</span><span class='va'>dfop_fit</span><span class='op'>)</span> <span class='co'># We don't see systematic deviations, but heteroscedastic residuals</span> -</div><div class='img'><img src='loftest-2.png' alt='' width='700' height='433' /></div><div class='input'><span class='co'># therefore we should consider adapting the error model, although we have</span> -<span class='fu'>loftest</span><span class='op'>(</span><span class='va'>dfop_fit</span><span class='op'>)</span> <span class='co'># no lack of fit</span> -</div><div class='output co'>#> Likelihood ratio test -#> -#> Model 1: ANOVA with error model const -#> Model 2: DFOP with error model const -#> #Df LogLik Df Chisq Pr(>Chisq) -#> 1 10 -40.710 -#> 2 5 -42.453 -5 3.485 0.6257</div><div class='input'><span class='co'>#</span> -<span class='co'># This is the anova model used internally for the comparison</span> -<span class='va'>test_data_anova</span> <span class='op'><-</span> <span class='va'>test_data</span> -<span class='va'>test_data_anova</span><span class='op'>$</span><span class='va'>time</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/factor.html'>as.factor</a></span><span class='op'>(</span><span class='va'>test_data_anova</span><span class='op'>$</span><span class='va'>time</span><span class='op'>)</span> -<span class='va'>anova_fit</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/lm.html'>lm</a></span><span class='op'>(</span><span class='va'>value</span> <span class='op'>~</span> <span class='va'>time</span>, data <span class='op'>=</span> <span class='va'>test_data_anova</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>anova_fit</span><span class='op'>)</span> -</div><div class='output co'>#> -#> Call: -#> lm(formula = value ~ time, data = test_data_anova) -#> -#> Residuals: -#> Min 1Q Median 3Q Max -#> -6.1000 -0.5625 0.0000 0.5625 6.1000 -#> -#> Coefficients: -#> Estimate Std. Error t value Pr(>|t|) -#> (Intercept) 103.150 2.323 44.409 7.44e-12 *** -#> time1 -19.950 3.285 -6.073 0.000185 *** -#> time3 -50.800 3.285 -15.465 8.65e-08 *** -#> time7 -68.500 3.285 -20.854 6.28e-09 *** -#> time14 -79.750 3.285 -24.278 1.63e-09 *** -#> time28 -86.000 3.285 -26.181 8.35e-10 *** -#> time60 -94.900 3.285 -28.891 3.48e-10 *** -#> time90 -98.500 3.285 -29.986 2.49e-10 *** -#> time120 -100.450 3.285 -30.580 2.09e-10 *** -#> --- -#> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 -#> -#> Residual standard error: 3.285 on 9 degrees of freedom -#> Multiple R-squared: 0.9953, Adjusted R-squared: 0.9912 -#> F-statistic: 240.5 on 8 and 9 DF, p-value: 1.417e-09 -#> </div><div class='input'><span class='fu'><a href='https://rdrr.io/r/stats/logLik.html'>logLik</a></span><span class='op'>(</span><span class='va'>anova_fit</span><span class='op'>)</span> <span class='co'># We get the same likelihood and degrees of freedom</span> -</div><div class='output co'>#> 'log Lik.' -40.71015 (df=10)</div><div class='input'><span class='co'>#</span> -<span class='va'>test_data_2</span> <span class='op'><-</span> <span class='va'>synthetic_data_for_UBA_2014</span><span class='op'>[[</span><span class='fl'>12</span><span class='op'>]</span><span class='op'>]</span><span class='op'>$</span><span class='va'>data</span> -<span class='va'>m_synth_SFO_lin</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"M1"</span><span class='op'>)</span>, - M1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"M2"</span><span class='op'>)</span>, - M2 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'><span class='va'>sfo_lin_fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>m_synth_SFO_lin</span>, <span class='va'>test_data_2</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'><a href='plot.mkinfit.html'>plot_res</a></span><span class='op'>(</span><span class='va'>sfo_lin_fit</span><span class='op'>)</span> <span class='co'># not a good model, we try parallel formation</span> -</div><div class='img'><img src='loftest-3.png' alt='' width='700' height='433' /></div><div class='input'><span class='fu'>loftest</span><span class='op'>(</span><span class='va'>sfo_lin_fit</span><span class='op'>)</span> -</div><div class='output co'>#> Likelihood ratio test -#> -#> Model 1: ANOVA with error model const -#> Model 2: m_synth_SFO_lin with error model const and fixed parameter(s) M1_0, M2_0 -#> #Df LogLik Df Chisq Pr(>Chisq) -#> 1 28 -93.606 -#> 2 7 -171.927 -21 156.64 < 2.2e-16 *** -#> --- -#> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</div><div class='input'><span class='co'>#</span> -<span class='va'>m_synth_SFO_par</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"M1"</span>, <span class='st'>"M2"</span><span class='op'>)</span><span class='op'>)</span>, - M1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, - M2 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'><span class='va'>sfo_par_fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>m_synth_SFO_par</span>, <span class='va'>test_data_2</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'><a href='plot.mkinfit.html'>plot_res</a></span><span class='op'>(</span><span class='va'>sfo_par_fit</span><span class='op'>)</span> <span class='co'># much better for metabolites</span> -</div><div class='img'><img src='loftest-4.png' alt='' width='700' height='433' /></div><div class='input'><span class='fu'>loftest</span><span class='op'>(</span><span class='va'>sfo_par_fit</span><span class='op'>)</span> -</div><div class='output co'>#> Likelihood ratio test -#> -#> Model 1: ANOVA with error model const -#> Model 2: m_synth_SFO_par with error model const and fixed parameter(s) M1_0, M2_0 -#> #Df LogLik Df Chisq Pr(>Chisq) -#> 1 28 -93.606 -#> 2 7 -156.331 -21 125.45 < 2.2e-16 *** -#> --- -#> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</div><div class='input'><span class='co'>#</span> -<span class='va'>m_synth_DFOP_par</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"DFOP"</span>, to <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"M1"</span>, <span class='st'>"M2"</span><span class='op'>)</span><span class='op'>)</span>, - M1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, - M2 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'><span class='va'>dfop_par_fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>m_synth_DFOP_par</span>, <span class='va'>test_data_2</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'><a href='plot.mkinfit.html'>plot_res</a></span><span class='op'>(</span><span class='va'>dfop_par_fit</span><span class='op'>)</span> <span class='co'># No visual lack of fit</span> -</div><div class='img'><img src='loftest-5.png' alt='' width='700' height='433' /></div><div class='input'><span class='fu'>loftest</span><span class='op'>(</span><span class='va'>dfop_par_fit</span><span class='op'>)</span> <span class='co'># no lack of fit found by the test</span> -</div><div class='output co'>#> Likelihood ratio test -#> -#> Model 1: ANOVA with error model const -#> Model 2: m_synth_DFOP_par with error model const and fixed parameter(s) M1_0, M2_0 -#> #Df LogLik Df Chisq Pr(>Chisq) -#> 1 28 -93.606 -#> 2 9 -102.763 -19 18.313 0.5016</div><div class='input'><span class='co'>#</span> -<span class='co'># The anova model used for comparison in the case of transformation products</span> -<span class='va'>test_data_anova_2</span> <span class='op'><-</span> <span class='va'>dfop_par_fit</span><span class='op'>$</span><span class='va'>data</span> -<span class='va'>test_data_anova_2</span><span class='op'>$</span><span class='va'>variable</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/factor.html'>as.factor</a></span><span class='op'>(</span><span class='va'>test_data_anova_2</span><span class='op'>$</span><span class='va'>variable</span><span class='op'>)</span> -<span class='va'>test_data_anova_2</span><span class='op'>$</span><span class='va'>time</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/factor.html'>as.factor</a></span><span class='op'>(</span><span class='va'>test_data_anova_2</span><span class='op'>$</span><span class='va'>time</span><span class='op'>)</span> -<span class='va'>anova_fit_2</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/lm.html'>lm</a></span><span class='op'>(</span><span class='va'>observed</span> <span class='op'>~</span> <span class='va'>time</span><span class='op'>:</span><span class='va'>variable</span> <span class='op'>-</span> <span class='fl'>1</span>, data <span class='op'>=</span> <span class='va'>test_data_anova_2</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>anova_fit_2</span><span class='op'>)</span> -</div><div class='output co'>#> -#> Call: -#> lm(formula = observed ~ time:variable - 1, data = test_data_anova_2) -#> -#> Residuals: -#> Min 1Q Median 3Q Max -#> -6.1000 -0.5875 0.0000 0.5875 6.1000 -#> -#> Coefficients: (2 not defined because of singularities) -#> Estimate Std. Error t value Pr(>|t|) -#> time0:variableparent 103.150 1.573 65.562 < 2e-16 *** -#> time1:variableparent 83.200 1.573 52.882 < 2e-16 *** -#> time3:variableparent 52.350 1.573 33.274 < 2e-16 *** -#> time7:variableparent 34.650 1.573 22.024 < 2e-16 *** -#> time14:variableparent 23.400 1.573 14.873 6.35e-14 *** -#> time28:variableparent 17.150 1.573 10.901 5.47e-11 *** -#> time60:variableparent 8.250 1.573 5.244 1.99e-05 *** -#> time90:variableparent 4.650 1.573 2.956 0.006717 ** -#> time120:variableparent 2.700 1.573 1.716 0.098507 . -#> time0:variableM1 NA NA NA NA -#> time1:variableM1 11.850 1.573 7.532 6.93e-08 *** -#> time3:variableM1 22.700 1.573 14.428 1.26e-13 *** -#> time7:variableM1 33.050 1.573 21.007 < 2e-16 *** -#> time14:variableM1 31.250 1.573 19.863 < 2e-16 *** -#> time28:variableM1 18.900 1.573 12.013 7.02e-12 *** -#> time60:variableM1 7.550 1.573 4.799 6.28e-05 *** -#> time90:variableM1 3.850 1.573 2.447 0.021772 * -#> time120:variableM1 2.050 1.573 1.303 0.204454 -#> time0:variableM2 NA NA NA NA -#> time1:variableM2 6.700 1.573 4.259 0.000254 *** -#> time3:variableM2 16.750 1.573 10.646 8.93e-11 *** -#> time7:variableM2 25.800 1.573 16.399 6.89e-15 *** -#> time14:variableM2 28.600 1.573 18.178 6.35e-16 *** -#> time28:variableM2 25.400 1.573 16.144 9.85e-15 *** -#> time60:variableM2 21.600 1.573 13.729 3.81e-13 *** -#> time90:variableM2 17.800 1.573 11.314 2.51e-11 *** -#> time120:variableM2 14.100 1.573 8.962 2.79e-09 *** -#> --- -#> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 -#> -#> Residual standard error: 2.225 on 25 degrees of freedom -#> Multiple R-squared: 0.9979, Adjusted R-squared: 0.9957 -#> F-statistic: 469.2 on 25 and 25 DF, p-value: < 2.2e-16 -#> </div><div class='input'><span class='co'># }</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="va">test_data</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">synthetic_data_for_UBA_2014</span><span class="op">[[</span><span class="fl">12</span><span class="op">]</span><span class="op">]</span><span class="op">$</span><span class="va">data</span>, <span class="va">name</span> <span class="op">==</span> <span class="st">"parent"</span><span class="op">)</span></span> +<span class="r-in"><span class="va">sfo_fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="va">test_data</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="plot.mkinfit.html">plot_res</a></span><span class="op">(</span><span class="va">sfo_fit</span><span class="op">)</span> <span class="co"># We see a clear pattern in the residuals</span></span> +<span class="r-plt img"><img src="loftest-1.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="fu">loftest</span><span class="op">(</span><span class="va">sfo_fit</span><span class="op">)</span> <span class="co"># We have a clear lack of fit</span></span> +<span class="r-out co"><span class="r-pr">#></span> Likelihood ratio test</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model 1: ANOVA with error model const</span> +<span class="r-out co"><span class="r-pr">#></span> Model 2: SFO with error model const</span> +<span class="r-out co"><span class="r-pr">#></span> #Df LogLik Df Chisq Pr(>Chisq) </span> +<span class="r-out co"><span class="r-pr">#></span> 1 10 -40.710 </span> +<span class="r-out co"><span class="r-pr">#></span> 2 3 -63.954 -7 46.487 7.027e-08 ***</span> +<span class="r-out co"><span class="r-pr">#></span> ---</span> +<span class="r-out co"><span class="r-pr">#></span> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</span> +<span class="r-in"><span class="co">#</span></span> +<span class="r-in"><span class="co"># We try a different model (the one that was used to generate the data)</span></span> +<span class="r-in"><span class="va">dfop_fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="va">test_data</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="plot.mkinfit.html">plot_res</a></span><span class="op">(</span><span class="va">dfop_fit</span><span class="op">)</span> <span class="co"># We don't see systematic deviations, but heteroscedastic residuals</span></span> +<span class="r-plt img"><img src="loftest-2.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="co"># therefore we should consider adapting the error model, although we have</span></span> +<span class="r-in"><span class="fu">loftest</span><span class="op">(</span><span class="va">dfop_fit</span><span class="op">)</span> <span class="co"># no lack of fit</span></span> +<span class="r-out co"><span class="r-pr">#></span> Likelihood ratio test</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model 1: ANOVA with error model const</span> +<span class="r-out co"><span class="r-pr">#></span> Model 2: DFOP with error model const</span> +<span class="r-out co"><span class="r-pr">#></span> #Df LogLik Df Chisq Pr(>Chisq)</span> +<span class="r-out co"><span class="r-pr">#></span> 1 10 -40.710 </span> +<span class="r-out co"><span class="r-pr">#></span> 2 5 -42.453 -5 3.485 0.6257</span> +<span class="r-in"><span class="co">#</span></span> +<span class="r-in"><span class="co"># This is the anova model used internally for the comparison</span></span> +<span class="r-in"><span class="va">test_data_anova</span> <span class="op"><-</span> <span class="va">test_data</span></span> +<span class="r-in"><span class="va">test_data_anova</span><span class="op">$</span><span class="va">time</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/factor.html" class="external-link">as.factor</a></span><span class="op">(</span><span class="va">test_data_anova</span><span class="op">$</span><span class="va">time</span><span class="op">)</span></span> +<span class="r-in"><span class="va">anova_fit</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/lm.html" class="external-link">lm</a></span><span class="op">(</span><span class="va">value</span> <span class="op">~</span> <span class="va">time</span>, data <span class="op">=</span> <span class="va">test_data_anova</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/summary.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">anova_fit</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Call:</span> +<span class="r-out co"><span class="r-pr">#></span> lm(formula = value ~ time, data = test_data_anova)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Residuals:</span> +<span class="r-out co"><span class="r-pr">#></span> Min 1Q Median 3Q Max </span> +<span class="r-out co"><span class="r-pr">#></span> -6.1000 -0.5625 0.0000 0.5625 6.1000 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Coefficients:</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Std. Error t value Pr(>|t|) </span> +<span class="r-out co"><span class="r-pr">#></span> (Intercept) 103.150 2.323 44.409 7.44e-12 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time1 -19.950 3.285 -6.073 0.000185 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time3 -50.800 3.285 -15.465 8.65e-08 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time7 -68.500 3.285 -20.854 6.28e-09 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time14 -79.750 3.285 -24.278 1.63e-09 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time28 -86.000 3.285 -26.181 8.35e-10 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time60 -94.900 3.285 -28.891 3.48e-10 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time90 -98.500 3.285 -29.986 2.49e-10 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time120 -100.450 3.285 -30.580 2.09e-10 ***</span> +<span class="r-out co"><span class="r-pr">#></span> ---</span> +<span class="r-out co"><span class="r-pr">#></span> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Residual standard error: 3.285 on 9 degrees of freedom</span> +<span class="r-out co"><span class="r-pr">#></span> Multiple R-squared: 0.9953, Adjusted R-squared: 0.9912 </span> +<span class="r-out co"><span class="r-pr">#></span> F-statistic: 240.5 on 8 and 9 DF, p-value: 1.417e-09</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/stats/logLik.html" class="external-link">logLik</a></span><span class="op">(</span><span class="va">anova_fit</span><span class="op">)</span> <span class="co"># We get the same likelihood and degrees of freedom</span></span> +<span class="r-out co"><span class="r-pr">#></span> 'log Lik.' -40.71015 (df=10)</span> +<span class="r-in"><span class="co">#</span></span> +<span class="r-in"><span class="va">test_data_2</span> <span class="op"><-</span> <span class="va">synthetic_data_for_UBA_2014</span><span class="op">[[</span><span class="fl">12</span><span class="op">]</span><span class="op">]</span><span class="op">$</span><span class="va">data</span></span> +<span class="r-in"><span class="va">m_synth_SFO_lin</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"M1"</span><span class="op">)</span>,</span> +<span class="r-in"> M1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"M2"</span><span class="op">)</span>,</span> +<span class="r-in"> M2 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>, use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="va">sfo_lin_fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">m_synth_SFO_lin</span>, <span class="va">test_data_2</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="plot.mkinfit.html">plot_res</a></span><span class="op">(</span><span class="va">sfo_lin_fit</span><span class="op">)</span> <span class="co"># not a good model, we try parallel formation</span></span> +<span class="r-plt img"><img src="loftest-3.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="fu">loftest</span><span class="op">(</span><span class="va">sfo_lin_fit</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Likelihood ratio test</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model 1: ANOVA with error model const</span> +<span class="r-out co"><span class="r-pr">#></span> Model 2: m_synth_SFO_lin with error model const and fixed parameter(s) M1_0, M2_0</span> +<span class="r-out co"><span class="r-pr">#></span> #Df LogLik Df Chisq Pr(>Chisq) </span> +<span class="r-out co"><span class="r-pr">#></span> 1 28 -93.606 </span> +<span class="r-out co"><span class="r-pr">#></span> 2 7 -171.927 -21 156.64 < 2.2e-16 ***</span> +<span class="r-out co"><span class="r-pr">#></span> ---</span> +<span class="r-out co"><span class="r-pr">#></span> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</span> +<span class="r-in"><span class="co">#</span></span> +<span class="r-in"><span class="va">m_synth_SFO_par</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"M1"</span>, <span class="st">"M2"</span><span class="op">)</span><span class="op">)</span>,</span> +<span class="r-in"> M1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> M2 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>, use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="va">sfo_par_fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">m_synth_SFO_par</span>, <span class="va">test_data_2</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="plot.mkinfit.html">plot_res</a></span><span class="op">(</span><span class="va">sfo_par_fit</span><span class="op">)</span> <span class="co"># much better for metabolites</span></span> +<span class="r-plt img"><img src="loftest-4.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="fu">loftest</span><span class="op">(</span><span class="va">sfo_par_fit</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Likelihood ratio test</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model 1: ANOVA with error model const</span> +<span class="r-out co"><span class="r-pr">#></span> Model 2: m_synth_SFO_par with error model const and fixed parameter(s) M1_0, M2_0</span> +<span class="r-out co"><span class="r-pr">#></span> #Df LogLik Df Chisq Pr(>Chisq) </span> +<span class="r-out co"><span class="r-pr">#></span> 1 28 -93.606 </span> +<span class="r-out co"><span class="r-pr">#></span> 2 7 -156.331 -21 125.45 < 2.2e-16 ***</span> +<span class="r-out co"><span class="r-pr">#></span> ---</span> +<span class="r-out co"><span class="r-pr">#></span> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</span> +<span class="r-in"><span class="co">#</span></span> +<span class="r-in"><span class="va">m_synth_DFOP_par</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"DFOP"</span>, to <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"M1"</span>, <span class="st">"M2"</span><span class="op">)</span><span class="op">)</span>,</span> +<span class="r-in"> M1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> M2 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>, use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="va">dfop_par_fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">m_synth_DFOP_par</span>, <span class="va">test_data_2</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="plot.mkinfit.html">plot_res</a></span><span class="op">(</span><span class="va">dfop_par_fit</span><span class="op">)</span> <span class="co"># No visual lack of fit</span></span> +<span class="r-plt img"><img src="loftest-5.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="fu">loftest</span><span class="op">(</span><span class="va">dfop_par_fit</span><span class="op">)</span> <span class="co"># no lack of fit found by the test</span></span> +<span class="r-out co"><span class="r-pr">#></span> Likelihood ratio test</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model 1: ANOVA with error model const</span> +<span class="r-out co"><span class="r-pr">#></span> Model 2: m_synth_DFOP_par with error model const and fixed parameter(s) M1_0, M2_0</span> +<span class="r-out co"><span class="r-pr">#></span> #Df LogLik Df Chisq Pr(>Chisq)</span> +<span class="r-out co"><span class="r-pr">#></span> 1 28 -93.606 </span> +<span class="r-out co"><span class="r-pr">#></span> 2 9 -102.763 -19 18.313 0.5016</span> +<span class="r-in"><span class="co">#</span></span> +<span class="r-in"><span class="co"># The anova model used for comparison in the case of transformation products</span></span> +<span class="r-in"><span class="va">test_data_anova_2</span> <span class="op"><-</span> <span class="va">dfop_par_fit</span><span class="op">$</span><span class="va">data</span></span> +<span class="r-in"><span class="va">test_data_anova_2</span><span class="op">$</span><span class="va">variable</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/factor.html" class="external-link">as.factor</a></span><span class="op">(</span><span class="va">test_data_anova_2</span><span class="op">$</span><span class="va">variable</span><span class="op">)</span></span> +<span class="r-in"><span class="va">test_data_anova_2</span><span class="op">$</span><span class="va">time</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/factor.html" class="external-link">as.factor</a></span><span class="op">(</span><span class="va">test_data_anova_2</span><span class="op">$</span><span class="va">time</span><span class="op">)</span></span> +<span class="r-in"><span class="va">anova_fit_2</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/lm.html" class="external-link">lm</a></span><span class="op">(</span><span class="va">observed</span> <span class="op">~</span> <span class="va">time</span><span class="op">:</span><span class="va">variable</span> <span class="op">-</span> <span class="fl">1</span>, data <span class="op">=</span> <span class="va">test_data_anova_2</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/summary.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">anova_fit_2</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Call:</span> +<span class="r-out co"><span class="r-pr">#></span> lm(formula = observed ~ time:variable - 1, data = test_data_anova_2)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Residuals:</span> +<span class="r-out co"><span class="r-pr">#></span> Min 1Q Median 3Q Max </span> +<span class="r-out co"><span class="r-pr">#></span> -6.1000 -0.5875 0.0000 0.5875 6.1000 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Coefficients: (2 not defined because of singularities)</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Std. Error t value Pr(>|t|) </span> +<span class="r-out co"><span class="r-pr">#></span> time0:variableparent 103.150 1.573 65.562 < 2e-16 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time1:variableparent 83.200 1.573 52.882 < 2e-16 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time3:variableparent 52.350 1.573 33.274 < 2e-16 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time7:variableparent 34.650 1.573 22.024 < 2e-16 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time14:variableparent 23.400 1.573 14.873 6.35e-14 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time28:variableparent 17.150 1.573 10.901 5.47e-11 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time60:variableparent 8.250 1.573 5.244 1.99e-05 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time90:variableparent 4.650 1.573 2.956 0.006717 ** </span> +<span class="r-out co"><span class="r-pr">#></span> time120:variableparent 2.700 1.573 1.716 0.098507 . </span> +<span class="r-out co"><span class="r-pr">#></span> time0:variableM1 NA NA NA NA </span> +<span class="r-out co"><span class="r-pr">#></span> time1:variableM1 11.850 1.573 7.532 6.93e-08 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time3:variableM1 22.700 1.573 14.428 1.26e-13 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time7:variableM1 33.050 1.573 21.007 < 2e-16 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time14:variableM1 31.250 1.573 19.863 < 2e-16 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time28:variableM1 18.900 1.573 12.013 7.02e-12 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time60:variableM1 7.550 1.573 4.799 6.28e-05 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time90:variableM1 3.850 1.573 2.447 0.021772 * </span> +<span class="r-out co"><span class="r-pr">#></span> time120:variableM1 2.050 1.573 1.303 0.204454 </span> +<span class="r-out co"><span class="r-pr">#></span> time0:variableM2 NA NA NA NA </span> +<span class="r-out co"><span class="r-pr">#></span> time1:variableM2 6.700 1.573 4.259 0.000254 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time3:variableM2 16.750 1.573 10.646 8.93e-11 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time7:variableM2 25.800 1.573 16.399 6.89e-15 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time14:variableM2 28.600 1.573 18.178 6.35e-16 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time28:variableM2 25.400 1.573 16.144 9.85e-15 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time60:variableM2 21.600 1.573 13.729 3.81e-13 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time90:variableM2 17.800 1.573 11.314 2.51e-11 ***</span> +<span class="r-out co"><span class="r-pr">#></span> time120:variableM2 14.100 1.573 8.962 2.79e-09 ***</span> +<span class="r-out co"><span class="r-pr">#></span> ---</span> +<span class="r-out co"><span class="r-pr">#></span> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Residual standard error: 2.225 on 25 degrees of freedom</span> +<span class="r-out co"><span class="r-pr">#></span> Multiple R-squared: 0.9979, Adjusted R-squared: 0.9957 </span> +<span class="r-out co"><span class="r-pr">#></span> F-statistic: 469.2 on 25 and 25 DF, p-value: < 2.2e-16</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/logLik.mkinfit.html b/docs/reference/logLik.mkinfit.html index 83fb4e48..dc1bfbba 100644 --- a/docs/reference/logLik.mkinfit.html +++ b/docs/reference/logLik.mkinfit.html @@ -1,71 +1,16 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Calculated the log-likelihood of a fitted mkinfit object — logLik.mkinfit • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Calculated the log-likelihood of a fitted mkinfit object — logLik.mkinfit" /> -<meta property="og:description" content="This function returns the product of the likelihood densities of each +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Calculated the log-likelihood of a fitted mkinfit object — logLik.mkinfit • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Calculated the log-likelihood of a fitted mkinfit object — logLik.mkinfit"><meta property="og:description" content="This function returns the product of the likelihood densities of each observed value, as calculated as part of the fitting procedure using dnorm, i.e. assuming normal distribution, and with the means predicted by the degradation model, and the standard deviations predicted by -the error model." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +the error model."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -76,13 +21,12 @@ the error model." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -91,8 +35,7 @@ the error model." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -102,6 +45,9 @@ the error model." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -116,122 +62,115 @@ the error model." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Calculated the log-likelihood of a fitted mkinfit object</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/logLik.mkinfit.R'><code>R/logLik.mkinfit.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/logLik.mkinfit.R" class="external-link"><code>R/logLik.mkinfit.R</code></a></small> <div class="hidden name"><code>logLik.mkinfit.Rd</code></div> </div> <div class="ref-description"> <p>This function returns the product of the likelihood densities of each observed value, as calculated as part of the fitting procedure using -<code><a href='https://rdrr.io/r/stats/Normal.html'>dnorm</a></code>, i.e. assuming normal distribution, and with the means +<code><a href="https://rdrr.io/r/stats/Normal.html" class="external-link">dnorm</a></code>, i.e. assuming normal distribution, and with the means predicted by the degradation model, and the standard deviations predicted by the error model.</p> </div> - <pre class="usage"><span class='co'># S3 method for mkinfit</span> -<span class='fu'><a href='https://rdrr.io/r/stats/logLik.html'>logLik</a></span><span class='op'>(</span><span class='va'>object</span>, <span class='va'>...</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>An object of class <code><a href='mkinfit.html'>mkinfit</a></code>.</p></td> - </tr> - <tr> - <th>...</th> - <td><p>For compatibility with the generic method</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - - <p>An object of class <code><a href='https://rdrr.io/r/stats/logLik.html'>logLik</a></code> with the number of estimated + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for mkinfit</span> +<span class="fu"><a href="https://rdrr.io/r/stats/logLik.html" class="external-link">logLik</a></span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>An object of class <code><a href="mkinfit.html">mkinfit</a></code>.</p></dd> +<dt>...</dt> +<dd><p>For compatibility with the generic method</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>An object of class <code><a href="https://rdrr.io/r/stats/logLik.html" class="external-link">logLik</a></code> with the number of estimated parameters (degradation model parameters plus variance model parameters) as attribute.</p> - <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2> - + </div> + <div id="details"> + <h2>Details</h2> <p>The total number of estimated parameters returned with the value of the likelihood is calculated as the sum of fitted degradation model parameters and the fitted error model parameters.</p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p>Compare the AIC of columns of <code><a href='mmkin.html'>mmkin</a></code> objects using -<code><a href='AIC.mmkin.html'>AIC.mmkin</a></code>.</p></div> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p>Compare the AIC of columns of <code><a href="mmkin.html">mmkin</a></code> objects using +<code><a href="AIC.mmkin.html">AIC.mmkin</a></code>.</p></div> + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> - <span class='co'># \dontrun{</span> - <span class='va'>sfo_sfo</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"m1"</span><span class='op'>)</span>, - m1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span> - <span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> <span class='va'>d_t</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/subset.html'>subset</a></span><span class='op'>(</span><span class='va'>FOCUS_2006_D</span>, <span class='va'>value</span> <span class='op'>!=</span> <span class='fl'>0</span><span class='op'>)</span> - <span class='va'>f_nw</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>sfo_sfo</span>, <span class='va'>d_t</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> <span class='co'># no weighting (weights are unity)</span> - <span class='va'>f_obs</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/update.html'>update</a></span><span class='op'>(</span><span class='va'>f_nw</span>, error_model <span class='op'>=</span> <span class='st'>"obs"</span><span class='op'>)</span> - <span class='va'>f_tc</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/update.html'>update</a></span><span class='op'>(</span><span class='va'>f_nw</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span><span class='op'>)</span> - <span class='fu'><a href='https://rdrr.io/r/stats/AIC.html'>AIC</a></span><span class='op'>(</span><span class='va'>f_nw</span>, <span class='va'>f_obs</span>, <span class='va'>f_tc</span><span class='op'>)</span> -</div><div class='output co'>#> df AIC -#> f_nw 5 204.4486 -#> f_obs 6 205.8727 -#> f_tc 6 141.9656</div><div class='input'> <span class='co'># }</span> - -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"> <span class="co"># \dontrun{</span></span> +<span class="r-in"> <span class="va">sfo_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"m1"</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span></span> +<span class="r-in"> <span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"> <span class="va">d_t</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">FOCUS_2006_D</span>, <span class="va">value</span> <span class="op">!=</span> <span class="fl">0</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">f_nw</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">sfo_sfo</span>, <span class="va">d_t</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span> <span class="co"># no weighting (weights are unity)</span></span> +<span class="r-in"> <span class="va">f_obs</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/update.html" class="external-link">update</a></span><span class="op">(</span><span class="va">f_nw</span>, error_model <span class="op">=</span> <span class="st">"obs"</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">f_tc</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/update.html" class="external-link">update</a></span><span class="op">(</span><span class="va">f_nw</span>, error_model <span class="op">=</span> <span class="st">"tc"</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">AIC</a></span><span class="op">(</span><span class="va">f_nw</span>, <span class="va">f_obs</span>, <span class="va">f_tc</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> df AIC</span> +<span class="r-out co"><span class="r-pr">#></span> f_nw 5 204.4486</span> +<span class="r-out co"><span class="r-pr">#></span> f_obs 6 205.8727</span> +<span class="r-out co"><span class="r-pr">#></span> f_tc 6 141.9656</span> +<span class="r-in"> <span class="co"># }</span></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/logistic.solution-1.png b/docs/reference/logistic.solution-1.png Binary files differindex 84d8e722..73dad0a4 100644 --- a/docs/reference/logistic.solution-1.png +++ b/docs/reference/logistic.solution-1.png diff --git a/docs/reference/logistic.solution-2.png b/docs/reference/logistic.solution-2.png Binary files differindex 73e6436d..8d2514a3 100644 --- a/docs/reference/logistic.solution-2.png +++ b/docs/reference/logistic.solution-2.png diff --git a/docs/reference/logistic.solution.html b/docs/reference/logistic.solution.html index d11e1b3c..5c3c2b42 100644 --- a/docs/reference/logistic.solution.html +++ b/docs/reference/logistic.solution.html @@ -1,68 +1,13 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Logistic kinetics — logistic.solution • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Logistic kinetics — logistic.solution" /> -<meta property="og:description" content="Function describing exponential decline from a defined starting value, with -an increasing rate constant, supposedly caused by microbial growth" /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Logistic kinetics — logistic.solution • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Logistic kinetics — logistic.solution"><meta property="og:description" content="Function describing exponential decline from a defined starting value, with +an increasing rate constant, supposedly caused by microbial growth"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -73,13 +18,12 @@ an increasing rate constant, supposedly caused by microbial growth" /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -88,8 +32,7 @@ an increasing rate constant, supposedly caused by microbial growth" /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -99,6 +42,9 @@ an increasing rate constant, supposedly caused by microbial growth" /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -113,34 +59,27 @@ an increasing rate constant, supposedly caused by microbial growth" /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Logistic kinetics</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/parent_solutions.R'><code>R/parent_solutions.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/parent_solutions.R" class="external-link"><code>R/parent_solutions.R</code></a></small> <div class="hidden name"><code>logistic.solution.Rd</code></div> </div> @@ -149,136 +88,132 @@ an increasing rate constant, supposedly caused by microbial growth" /> an increasing rate constant, supposedly caused by microbial growth</p> </div> - <pre class="usage"><span class='fu'>logistic.solution</span><span class='op'>(</span><span class='va'>t</span>, <span class='va'>parent_0</span>, <span class='va'>kmax</span>, <span class='va'>k0</span>, <span class='va'>r</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>t</th> - <td><p>Time.</p></td> - </tr> - <tr> - <th>parent_0</th> - <td><p>Starting value for the response variable at time zero.</p></td> - </tr> - <tr> - <th>kmax</th> - <td><p>Maximum rate constant.</p></td> - </tr> - <tr> - <th>k0</th> - <td><p>Minimum rate constant effective at time zero.</p></td> - </tr> - <tr> - <th>r</th> - <td><p>Growth rate of the increase in the rate constant.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">logistic.solution</span><span class="op">(</span><span class="va">t</span>, <span class="va">parent_0</span>, <span class="va">kmax</span>, <span class="va">k0</span>, <span class="va">r</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>t</dt> +<dd><p>Time.</p></dd> +<dt>parent_0</dt> +<dd><p>Starting value for the response variable at time zero.</p></dd> +<dt>kmax</dt> +<dd><p>Maximum rate constant.</p></dd> +<dt>k0</dt> +<dd><p>Minimum rate constant effective at time zero.</p></dd> +<dt>r</dt> +<dd><p>Growth rate of the increase in the rate constant.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The value of the response variable at time <code>t</code>.</p> - <h2 class="hasAnchor" id="note"><a class="anchor" href="#note"></a>Note</h2> - + </div> + <div id="note"> + <h2>Note</h2> <p>The solution of the logistic model reduces to the -<code><a href='SFO.solution.html'>SFO.solution</a></code> if <code>k0</code> is equal to <code>kmax</code>.</p> - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - - <p>FOCUS (2006) “Guidance Document on Estimating Persistence +<code><a href="SFO.solution.html">SFO.solution</a></code> if <code>k0</code> is equal to <code>kmax</code>.</p> + </div> + <div id="references"> + <h2>References</h2> + <p>FOCUS (2006) “Guidance Document on Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC Document Reference Sanco/10058/2005 version 2.0, 434 pp, -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a> -FOCUS (2014) “Generic guidance for Estimating Persistence +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a> +FOCUS (2014) “Generic guidance for Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, Version 1.1, 18 December 2014 -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p>Other parent solutions: -<code><a href='DFOP.solution.html'>DFOP.solution</a>()</code>, -<code><a href='FOMC.solution.html'>FOMC.solution</a>()</code>, -<code><a href='HS.solution.html'>HS.solution</a>()</code>, -<code><a href='IORE.solution.html'>IORE.solution</a>()</code>, -<code><a href='SFO.solution.html'>SFO.solution</a>()</code>, -<code><a href='SFORB.solution.html'>SFORB.solution</a>()</code></p></div> - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> - <span class='co'># Reproduce the plot on page 57 of FOCUS (2014)</span> - <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='fu'>logistic.solution</span><span class='op'>(</span><span class='va'>x</span>, <span class='fl'>100</span>, <span class='fl'>0.08</span>, <span class='fl'>0.0001</span>, <span class='fl'>0.2</span><span class='op'>)</span>, - from <span class='op'>=</span> <span class='fl'>0</span>, to <span class='op'>=</span> <span class='fl'>100</span>, ylim <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>100</span><span class='op'>)</span>, - xlab <span class='op'>=</span> <span class='st'>"Time"</span>, ylab <span class='op'>=</span> <span class='st'>"Residue"</span><span class='op'>)</span> -</div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='fu'>logistic.solution</span><span class='op'>(</span><span class='va'>x</span>, <span class='fl'>100</span>, <span class='fl'>0.08</span>, <span class='fl'>0.0001</span>, <span class='fl'>0.4</span><span class='op'>)</span>, - from <span class='op'>=</span> <span class='fl'>0</span>, to <span class='op'>=</span> <span class='fl'>100</span>, add <span class='op'>=</span> <span class='cn'>TRUE</span>, lty <span class='op'>=</span> <span class='fl'>2</span>, col <span class='op'>=</span> <span class='fl'>2</span><span class='op'>)</span> -</div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='fu'>logistic.solution</span><span class='op'>(</span><span class='va'>x</span>, <span class='fl'>100</span>, <span class='fl'>0.08</span>, <span class='fl'>0.0001</span>, <span class='fl'>0.8</span><span class='op'>)</span>, - from <span class='op'>=</span> <span class='fl'>0</span>, to <span class='op'>=</span> <span class='fl'>100</span>, add <span class='op'>=</span> <span class='cn'>TRUE</span>, lty <span class='op'>=</span> <span class='fl'>3</span>, col <span class='op'>=</span> <span class='fl'>3</span><span class='op'>)</span> -</div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='fu'>logistic.solution</span><span class='op'>(</span><span class='va'>x</span>, <span class='fl'>100</span>, <span class='fl'>0.08</span>, <span class='fl'>0.001</span>, <span class='fl'>0.2</span><span class='op'>)</span>, - from <span class='op'>=</span> <span class='fl'>0</span>, to <span class='op'>=</span> <span class='fl'>100</span>, add <span class='op'>=</span> <span class='cn'>TRUE</span>, lty <span class='op'>=</span> <span class='fl'>4</span>, col <span class='op'>=</span> <span class='fl'>4</span><span class='op'>)</span> -</div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='fu'>logistic.solution</span><span class='op'>(</span><span class='va'>x</span>, <span class='fl'>100</span>, <span class='fl'>0.08</span>, <span class='fl'>0.08</span>, <span class='fl'>0.2</span><span class='op'>)</span>, - from <span class='op'>=</span> <span class='fl'>0</span>, to <span class='op'>=</span> <span class='fl'>100</span>, add <span class='op'>=</span> <span class='cn'>TRUE</span>, lty <span class='op'>=</span> <span class='fl'>5</span>, col <span class='op'>=</span> <span class='fl'>5</span><span class='op'>)</span> -</div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/graphics/legend.html'>legend</a></span><span class='op'>(</span><span class='st'>"topright"</span>, inset <span class='op'>=</span> <span class='fl'>0.05</span>, - legend <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/paste.html'>paste0</a></span><span class='op'>(</span><span class='st'>"k0 = "</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0.0001</span>, <span class='fl'>0.0001</span>, <span class='fl'>0.0001</span>, <span class='fl'>0.001</span>, <span class='fl'>0.08</span><span class='op'>)</span>, - <span class='st'>", r = "</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0.2</span>, <span class='fl'>0.4</span>, <span class='fl'>0.8</span>, <span class='fl'>0.2</span>, <span class='fl'>0.2</span><span class='op'>)</span><span class='op'>)</span>, - lty <span class='op'>=</span> <span class='fl'>1</span><span class='op'>:</span><span class='fl'>5</span>, col <span class='op'>=</span> <span class='fl'>1</span><span class='op'>:</span><span class='fl'>5</span><span class='op'>)</span> -</div><div class='img'><img src='logistic.solution-1.png' alt='' width='700' height='433' /></div><div class='input'> - <span class='co'># Fit with synthetic data</span> - <span class='va'>logistic</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"logistic"</span><span class='op'>)</span><span class='op'>)</span> - - <span class='va'>sampling_times</span> <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>1</span>, <span class='fl'>3</span>, <span class='fl'>7</span>, <span class='fl'>14</span>, <span class='fl'>28</span>, <span class='fl'>60</span>, <span class='fl'>90</span>, <span class='fl'>120</span><span class='op'>)</span> - <span class='va'>parms_logistic</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>kmax <span class='op'>=</span> <span class='fl'>0.08</span>, k0 <span class='op'>=</span> <span class='fl'>0.0001</span>, r <span class='op'>=</span> <span class='fl'>0.2</span><span class='op'>)</span> - <span class='va'>d_logistic</span> <span class='op'><-</span> <span class='fu'><a href='mkinpredict.html'>mkinpredict</a></span><span class='op'>(</span><span class='va'>logistic</span>, - <span class='va'>parms_logistic</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>100</span><span class='op'>)</span>, - <span class='va'>sampling_times</span><span class='op'>)</span> - <span class='va'>d_2_1</span> <span class='op'><-</span> <span class='fu'><a href='add_err.html'>add_err</a></span><span class='op'>(</span><span class='va'>d_logistic</span>, - sdfunc <span class='op'>=</span> <span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='fu'><a href='sigma_twocomp.html'>sigma_twocomp</a></span><span class='op'>(</span><span class='va'>x</span>, <span class='fl'>0.5</span>, <span class='fl'>0.07</span><span class='op'>)</span>, - n <span class='op'>=</span> <span class='fl'>1</span>, reps <span class='op'>=</span> <span class='fl'>2</span>, digits <span class='op'>=</span> <span class='fl'>5</span>, LOD <span class='op'>=</span> <span class='fl'>0.1</span>, seed <span class='op'>=</span> <span class='fl'>123456</span><span class='op'>)</span><span class='op'>[[</span><span class='fl'>1</span><span class='op'>]</span><span class='op'>]</span> +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p>Other parent solutions: +<code><a href="DFOP.solution.html">DFOP.solution</a>()</code>, +<code><a href="FOMC.solution.html">FOMC.solution</a>()</code>, +<code><a href="HS.solution.html">HS.solution</a>()</code>, +<code><a href="IORE.solution.html">IORE.solution</a>()</code>, +<code><a href="SFO.solution.html">SFO.solution</a>()</code>, +<code><a href="SFORB.solution.html">SFORB.solution</a>()</code></p></div> + </div> - <span class='va'>m</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"logistic"</span>, <span class='va'>d_2_1</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - <span class='fu'><a href='plot.mkinfit.html'>plot_sep</a></span><span class='op'>(</span><span class='va'>m</span><span class='op'>)</span> -</div><div class='img'><img src='logistic.solution-2.png' alt='' width='700' height='433' /></div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>m</span><span class='op'>)</span><span class='op'>$</span><span class='va'>bpar</span> -</div><div class='output co'>#> Estimate se_notrans t value Pr(>t) Lower -#> parent_0 1.057896e+02 1.9023449590 55.610120 3.768360e-16 1.016451e+02 -#> kmax 6.398190e-02 0.0143201029 4.467978 3.841828e-04 3.929235e-02 -#> k0 1.612775e-04 0.0005866813 0.274898 3.940351e-01 5.846688e-08 -#> r 2.263946e-01 0.1718110662 1.317695 1.061043e-01 4.335843e-02 -#> sigma 5.332935e+00 0.9145907310 5.830952 4.036926e-05 3.340213e+00 -#> Upper -#> parent_0 109.9341588 -#> kmax 0.1041853 -#> k0 0.4448749 -#> r 1.1821120 -#> sigma 7.3256566</div><div class='input'> <span class='fu'><a href='endpoints.html'>endpoints</a></span><span class='op'>(</span><span class='va'>m</span><span class='op'>)</span><span class='op'>$</span><span class='va'>distimes</span> -</div><div class='output co'>#> DT50 DT90 DT50_k0 DT50_kmax -#> parent 36.86533 62.41511 4297.853 10.83349</div><div class='input'> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"> <span class="co"># Reproduce the plot on page 57 of FOCUS (2014)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu">logistic.solution</span><span class="op">(</span><span class="va">x</span>, <span class="fl">100</span>, <span class="fl">0.08</span>, <span class="fl">0.0001</span>, <span class="fl">0.2</span><span class="op">)</span>,</span> +<span class="r-in"> from <span class="op">=</span> <span class="fl">0</span>, to <span class="op">=</span> <span class="fl">100</span>, ylim <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">100</span><span class="op">)</span>,</span> +<span class="r-in"> xlab <span class="op">=</span> <span class="st">"Time"</span>, ylab <span class="op">=</span> <span class="st">"Residue"</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu">logistic.solution</span><span class="op">(</span><span class="va">x</span>, <span class="fl">100</span>, <span class="fl">0.08</span>, <span class="fl">0.0001</span>, <span class="fl">0.4</span><span class="op">)</span>,</span> +<span class="r-in"> from <span class="op">=</span> <span class="fl">0</span>, to <span class="op">=</span> <span class="fl">100</span>, add <span class="op">=</span> <span class="cn">TRUE</span>, lty <span class="op">=</span> <span class="fl">2</span>, col <span class="op">=</span> <span class="fl">2</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu">logistic.solution</span><span class="op">(</span><span class="va">x</span>, <span class="fl">100</span>, <span class="fl">0.08</span>, <span class="fl">0.0001</span>, <span class="fl">0.8</span><span class="op">)</span>,</span> +<span class="r-in"> from <span class="op">=</span> <span class="fl">0</span>, to <span class="op">=</span> <span class="fl">100</span>, add <span class="op">=</span> <span class="cn">TRUE</span>, lty <span class="op">=</span> <span class="fl">3</span>, col <span class="op">=</span> <span class="fl">3</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu">logistic.solution</span><span class="op">(</span><span class="va">x</span>, <span class="fl">100</span>, <span class="fl">0.08</span>, <span class="fl">0.001</span>, <span class="fl">0.2</span><span class="op">)</span>,</span> +<span class="r-in"> from <span class="op">=</span> <span class="fl">0</span>, to <span class="op">=</span> <span class="fl">100</span>, add <span class="op">=</span> <span class="cn">TRUE</span>, lty <span class="op">=</span> <span class="fl">4</span>, col <span class="op">=</span> <span class="fl">4</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu">logistic.solution</span><span class="op">(</span><span class="va">x</span>, <span class="fl">100</span>, <span class="fl">0.08</span>, <span class="fl">0.08</span>, <span class="fl">0.2</span><span class="op">)</span>,</span> +<span class="r-in"> from <span class="op">=</span> <span class="fl">0</span>, to <span class="op">=</span> <span class="fl">100</span>, add <span class="op">=</span> <span class="cn">TRUE</span>, lty <span class="op">=</span> <span class="fl">5</span>, col <span class="op">=</span> <span class="fl">5</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/legend.html" class="external-link">legend</a></span><span class="op">(</span><span class="st">"topright"</span>, inset <span class="op">=</span> <span class="fl">0.05</span>,</span> +<span class="r-in"> legend <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste0</a></span><span class="op">(</span><span class="st">"k0 = "</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0.0001</span>, <span class="fl">0.0001</span>, <span class="fl">0.0001</span>, <span class="fl">0.001</span>, <span class="fl">0.08</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="st">", r = "</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0.2</span>, <span class="fl">0.4</span>, <span class="fl">0.8</span>, <span class="fl">0.2</span>, <span class="fl">0.2</span><span class="op">)</span><span class="op">)</span>,</span> +<span class="r-in"> lty <span class="op">=</span> <span class="fl">1</span><span class="op">:</span><span class="fl">5</span>, col <span class="op">=</span> <span class="fl">1</span><span class="op">:</span><span class="fl">5</span><span class="op">)</span></span> +<span class="r-plt img"><img src="logistic.solution-1.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +<span class="r-in"> <span class="co"># Fit with synthetic data</span></span> +<span class="r-in"> <span class="va">logistic</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"logistic"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"> <span class="va">sampling_times</span> <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">1</span>, <span class="fl">3</span>, <span class="fl">7</span>, <span class="fl">14</span>, <span class="fl">28</span>, <span class="fl">60</span>, <span class="fl">90</span>, <span class="fl">120</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">parms_logistic</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>kmax <span class="op">=</span> <span class="fl">0.08</span>, k0 <span class="op">=</span> <span class="fl">0.0001</span>, r <span class="op">=</span> <span class="fl">0.2</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">d_logistic</span> <span class="op"><-</span> <span class="fu"><a href="mkinpredict.html">mkinpredict</a></span><span class="op">(</span><span class="va">logistic</span>,</span> +<span class="r-in"> <span class="va">parms_logistic</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">sampling_times</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">d_2_1</span> <span class="op"><-</span> <span class="fu"><a href="add_err.html">add_err</a></span><span class="op">(</span><span class="va">d_logistic</span>,</span> +<span class="r-in"> sdfunc <span class="op">=</span> <span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu"><a href="sigma_twocomp.html">sigma_twocomp</a></span><span class="op">(</span><span class="va">x</span>, <span class="fl">0.5</span>, <span class="fl">0.07</span><span class="op">)</span>,</span> +<span class="r-in"> n <span class="op">=</span> <span class="fl">1</span>, reps <span class="op">=</span> <span class="fl">2</span>, digits <span class="op">=</span> <span class="fl">5</span>, LOD <span class="op">=</span> <span class="fl">0.1</span>, seed <span class="op">=</span> <span class="fl">123456</span><span class="op">)</span><span class="op">[[</span><span class="fl">1</span><span class="op">]</span><span class="op">]</span></span> +<span class="r-in"></span> +<span class="r-in"> <span class="va">m</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"logistic"</span>, <span class="va">d_2_1</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="plot.mkinfit.html">plot_sep</a></span><span class="op">(</span><span class="va">m</span><span class="op">)</span></span> +<span class="r-plt img"><img src="logistic.solution-2.png" alt="" width="700" height="433"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/summary.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">m</span><span class="op">)</span><span class="op">$</span><span class="va">bpar</span></span> +<span class="r-out co"><span class="r-pr">#></span> Estimate se_notrans t value Pr(>t) Lower</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 1.057896e+02 1.9023449590 55.610120 3.768360e-16 1.016451e+02</span> +<span class="r-out co"><span class="r-pr">#></span> kmax 6.398190e-02 0.0143201029 4.467978 3.841828e-04 3.929235e-02</span> +<span class="r-out co"><span class="r-pr">#></span> k0 1.612775e-04 0.0005866813 0.274898 3.940351e-01 5.846688e-08</span> +<span class="r-out co"><span class="r-pr">#></span> r 2.263946e-01 0.1718110662 1.317695 1.061043e-01 4.335843e-02</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 5.332935e+00 0.9145907310 5.830952 4.036926e-05 3.340213e+00</span> +<span class="r-out co"><span class="r-pr">#></span> Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 109.9341588</span> +<span class="r-out co"><span class="r-pr">#></span> kmax 0.1041853</span> +<span class="r-out co"><span class="r-pr">#></span> k0 0.4448749</span> +<span class="r-out co"><span class="r-pr">#></span> r 1.1821120</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 7.3256566</span> +<span class="r-in"> <span class="fu"><a href="endpoints.html">endpoints</a></span><span class="op">(</span><span class="va">m</span><span class="op">)</span><span class="op">$</span><span class="va">distimes</span></span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90 DT50_k0 DT50_kmax</span> +<span class="r-out co"><span class="r-pr">#></span> parent 36.86533 62.41511 4297.853 10.83349</span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/lrtest.mkinfit.html b/docs/reference/lrtest.mkinfit.html index d670fb0c..d4355c43 100644 --- a/docs/reference/lrtest.mkinfit.html +++ b/docs/reference/lrtest.mkinfit.html @@ -1,71 +1,16 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Likelihood ratio test for mkinfit models — lrtest.mkinfit • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Likelihood ratio test for mkinfit models — lrtest.mkinfit" /> -<meta property="og:description" content="Compare two mkinfit models based on their likelihood. If two fitted +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Likelihood ratio test for mkinfit models — lrtest.mkinfit • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Likelihood ratio test for mkinfit models — lrtest.mkinfit"><meta property="og:description" content="Compare two mkinfit models based on their likelihood. If two fitted mkinfit objects are given as arguments, it is checked if they have been fitted to the same data. It is the responsibility of the user to make sure that the models are nested, i.e. one of them has less degrees of freedom -and can be expressed by fixing the parameters of the other." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +and can be expressed by fixing the parameters of the other."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -76,13 +21,12 @@ and can be expressed by fixing the parameters of the other." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -91,8 +35,7 @@ and can be expressed by fixing the parameters of the other." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -102,6 +45,9 @@ and can be expressed by fixing the parameters of the other." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -116,34 +62,27 @@ and can be expressed by fixing the parameters of the other." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Likelihood ratio test for mkinfit models</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/lrtest.mkinfit.R'><code>R/lrtest.mkinfit.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/lrtest.mkinfit.R" class="external-link"><code>R/lrtest.mkinfit.R</code></a></small> <div class="hidden name"><code>lrtest.mkinfit.Rd</code></div> </div> @@ -155,115 +94,112 @@ that the models are nested, i.e. one of them has less degrees of freedom and can be expressed by fixing the parameters of the other.</p> </div> - <pre class="usage"><span class='co'># S3 method for mkinfit</span> -<span class='fu'><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a></span><span class='op'>(</span><span class='va'>object</span>, object_2 <span class='op'>=</span> <span class='cn'>NULL</span>, <span class='va'>...</span><span class='op'>)</span> - -<span class='co'># S3 method for mmkin</span> -<span class='fu'><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a></span><span class='op'>(</span><span class='va'>object</span>, <span class='va'>...</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>An <code><a href='mkinfit.html'>mkinfit</a></code> object, or an <code><a href='mmkin.html'>mmkin</a></code> column -object containing two fits to the same data.</p></td> - </tr> - <tr> - <th>object_2</th> - <td><p>Optionally, another mkinfit object fitted to the same data.</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Argument to <code><a href='mkinfit.html'>mkinfit</a></code>, passed to -<code><a href='update.mkinfit.html'>update.mkinfit</a></code> for creating the alternative fitted object.</p></td> - </tr> - </table> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for mkinfit</span> +<span class="fu"><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a></span><span class="op">(</span><span class="va">object</span>, object_2 <span class="op">=</span> <span class="cn">NULL</span>, <span class="va">...</span><span class="op">)</span> - <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2> +<span class="co"># S3 method for mmkin</span> +<span class="fu"><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a></span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>An <code><a href="mkinfit.html">mkinfit</a></code> object, or an <code><a href="mmkin.html">mmkin</a></code> column +object containing two fits to the same data.</p></dd> +<dt>object_2</dt> +<dd><p>Optionally, another mkinfit object fitted to the same data.</p></dd> +<dt>...</dt> +<dd><p>Argument to <code><a href="mkinfit.html">mkinfit</a></code>, passed to +<code><a href="update.mkinfit.html">update.mkinfit</a></code> for creating the alternative fitted object.</p></dd> +</dl></div> + <div id="details"> + <h2>Details</h2> <p>Alternatively, an argument to mkinfit can be given which is then passed -to <code><a href='update.mkinfit.html'>update.mkinfit</a></code> to obtain the alternative model.</p> -<p>The comparison is then made by the <code><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest.default</a></code> +to <code><a href="update.mkinfit.html">update.mkinfit</a></code> to obtain the alternative model.</p> +<p>The comparison is then made by the <code><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest.default</a></code> method from the lmtest package. The model with the higher number of fitted parameters (alternative hypothesis) is listed first, then the model with the lower number of fitted parameters (null hypothesis).</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='co'># \dontrun{</span> -<span class='va'>test_data</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/subset.html'>subset</a></span><span class='op'>(</span><span class='va'>synthetic_data_for_UBA_2014</span><span class='op'>[[</span><span class='fl'>12</span><span class='op'>]</span><span class='op'>]</span><span class='op'>$</span><span class='va'>data</span>, <span class='va'>name</span> <span class='op'>==</span> <span class='st'>"parent"</span><span class='op'>)</span> -<span class='va'>sfo_fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='va'>test_data</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='va'>dfop_fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"DFOP"</span>, <span class='va'>test_data</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a></span><span class='op'>(</span><span class='va'>dfop_fit</span>, <span class='va'>sfo_fit</span><span class='op'>)</span> -</div><div class='output co'>#> Likelihood ratio test -#> -#> Model 1: DFOP with error model const -#> Model 2: SFO with error model const -#> #Df LogLik Df Chisq Pr(>Chisq) -#> 1 5 -42.453 -#> 2 3 -63.954 -2 43.002 4.594e-10 *** -#> --- -#> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</div><div class='input'><span class='fu'><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a></span><span class='op'>(</span><span class='va'>sfo_fit</span>, <span class='va'>dfop_fit</span><span class='op'>)</span> -</div><div class='output co'>#> Likelihood ratio test -#> -#> Model 1: DFOP with error model const -#> Model 2: SFO with error model const -#> #Df LogLik Df Chisq Pr(>Chisq) -#> 1 5 -42.453 -#> 2 3 -63.954 -2 43.002 4.594e-10 *** -#> --- -#> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</div><div class='input'> -<span class='co'># The following two examples are commented out as they fail during</span> -<span class='co'># generation of the static help pages by pkgdown</span> -<span class='co'>#lrtest(dfop_fit, error_model = "tc")</span> -<span class='co'>#lrtest(dfop_fit, fixed_parms = c(k2 = 0))</span> - -<span class='co'># However, this equivalent syntax also works for static help pages</span> -<span class='fu'><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a></span><span class='op'>(</span><span class='va'>dfop_fit</span>, <span class='fu'><a href='https://rdrr.io/r/stats/update.html'>update</a></span><span class='op'>(</span><span class='va'>dfop_fit</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> Likelihood ratio test -#> -#> Model 1: DFOP with error model tc -#> Model 2: DFOP with error model const -#> #Df LogLik Df Chisq Pr(>Chisq) -#> 1 6 -34.587 -#> 2 5 -42.453 -1 15.731 7.302e-05 *** -#> --- -#> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</div><div class='input'><span class='fu'><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a></span><span class='op'>(</span><span class='va'>dfop_fit</span>, <span class='fu'><a href='https://rdrr.io/r/stats/update.html'>update</a></span><span class='op'>(</span><span class='va'>dfop_fit</span>, fixed_parms <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k2 <span class='op'>=</span> <span class='fl'>0</span><span class='op'>)</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> Likelihood ratio test -#> -#> Model 1: DFOP with error model const -#> Model 2: DFOP with error model const and fixed parameter(s) k2 -#> #Df LogLik Df Chisq Pr(>Chisq) -#> 1 5 -42.453 -#> 2 4 -57.340 -1 29.776 4.851e-08 *** -#> --- -#> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</div><div class='input'><span class='co'># }</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="va">test_data</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">synthetic_data_for_UBA_2014</span><span class="op">[[</span><span class="fl">12</span><span class="op">]</span><span class="op">]</span><span class="op">$</span><span class="va">data</span>, <span class="va">name</span> <span class="op">==</span> <span class="st">"parent"</span><span class="op">)</span></span> +<span class="r-in"><span class="va">sfo_fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="va">test_data</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">dfop_fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="va">test_data</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a></span><span class="op">(</span><span class="va">dfop_fit</span>, <span class="va">sfo_fit</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Likelihood ratio test</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model 1: DFOP with error model const</span> +<span class="r-out co"><span class="r-pr">#></span> Model 2: SFO with error model const</span> +<span class="r-out co"><span class="r-pr">#></span> #Df LogLik Df Chisq Pr(>Chisq) </span> +<span class="r-out co"><span class="r-pr">#></span> 1 5 -42.453 </span> +<span class="r-out co"><span class="r-pr">#></span> 2 3 -63.954 -2 43.002 4.594e-10 ***</span> +<span class="r-out co"><span class="r-pr">#></span> ---</span> +<span class="r-out co"><span class="r-pr">#></span> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a></span><span class="op">(</span><span class="va">sfo_fit</span>, <span class="va">dfop_fit</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Likelihood ratio test</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model 1: DFOP with error model const</span> +<span class="r-out co"><span class="r-pr">#></span> Model 2: SFO with error model const</span> +<span class="r-out co"><span class="r-pr">#></span> #Df LogLik Df Chisq Pr(>Chisq) </span> +<span class="r-out co"><span class="r-pr">#></span> 1 5 -42.453 </span> +<span class="r-out co"><span class="r-pr">#></span> 2 3 -63.954 -2 43.002 4.594e-10 ***</span> +<span class="r-out co"><span class="r-pr">#></span> ---</span> +<span class="r-out co"><span class="r-pr">#></span> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># The following two examples are commented out as they fail during</span></span> +<span class="r-in"><span class="co"># generation of the static help pages by pkgdown</span></span> +<span class="r-in"><span class="co">#lrtest(dfop_fit, error_model = "tc")</span></span> +<span class="r-in"><span class="co">#lrtest(dfop_fit, fixed_parms = c(k2 = 0))</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># However, this equivalent syntax also works for static help pages</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a></span><span class="op">(</span><span class="va">dfop_fit</span>, <span class="fu"><a href="https://rdrr.io/r/stats/update.html" class="external-link">update</a></span><span class="op">(</span><span class="va">dfop_fit</span>, error_model <span class="op">=</span> <span class="st">"tc"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Likelihood ratio test</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model 1: DFOP with error model tc</span> +<span class="r-out co"><span class="r-pr">#></span> Model 2: DFOP with error model const</span> +<span class="r-out co"><span class="r-pr">#></span> #Df LogLik Df Chisq Pr(>Chisq) </span> +<span class="r-out co"><span class="r-pr">#></span> 1 6 -34.587 </span> +<span class="r-out co"><span class="r-pr">#></span> 2 5 -42.453 -1 15.731 7.302e-05 ***</span> +<span class="r-out co"><span class="r-pr">#></span> ---</span> +<span class="r-out co"><span class="r-pr">#></span> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a></span><span class="op">(</span><span class="va">dfop_fit</span>, <span class="fu"><a href="https://rdrr.io/r/stats/update.html" class="external-link">update</a></span><span class="op">(</span><span class="va">dfop_fit</span>, fixed_parms <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k2 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Likelihood ratio test</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model 1: DFOP with error model const</span> +<span class="r-out co"><span class="r-pr">#></span> Model 2: DFOP with error model const and fixed parameter(s) k2</span> +<span class="r-out co"><span class="r-pr">#></span> #Df LogLik Df Chisq Pr(>Chisq) </span> +<span class="r-out co"><span class="r-pr">#></span> 1 5 -42.453 </span> +<span class="r-out co"><span class="r-pr">#></span> 2 4 -57.340 -1 29.776 4.851e-08 ***</span> +<span class="r-out co"><span class="r-pr">#></span> ---</span> +<span class="r-out co"><span class="r-pr">#></span> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/max_twa_parent.html b/docs/reference/max_twa_parent.html index 4d473893..03b0263d 100644 --- a/docs/reference/max_twa_parent.html +++ b/docs/reference/max_twa_parent.html @@ -1,73 +1,18 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Function to calculate maximum time weighted average concentrations from -kinetic models fitted with mkinfit — max_twa_parent • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Function to calculate maximum time weighted average concentrations from -kinetic models fitted with mkinfit — max_twa_parent" /> -<meta property="og:description" content="This function calculates maximum moving window time weighted average +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Function to calculate maximum time weighted average concentrations from +kinetic models fitted with mkinfit — max_twa_parent • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Function to calculate maximum time weighted average concentrations from +kinetic models fitted with mkinfit — max_twa_parent"><meta property="og:description" content="This function calculates maximum moving window time weighted average concentrations (TWAs) for kinetic models fitted with mkinfit. Currently, only calculations for the parent are implemented for the SFO, FOMC, DFOP and HS models, using the analytical formulas given in the PEC -soil section of the FOCUS guidance." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +soil section of the FOCUS guidance."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -78,13 +23,12 @@ soil section of the FOCUS guidance." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -93,8 +37,7 @@ soil section of the FOCUS guidance." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -104,6 +47,9 @@ soil section of the FOCUS guidance." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -118,157 +64,130 @@ soil section of the FOCUS guidance." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Function to calculate maximum time weighted average concentrations from kinetic models fitted with mkinfit</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/max_twa_parent.R'><code>R/max_twa_parent.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/max_twa_parent.R" class="external-link"><code>R/max_twa_parent.R</code></a></small> <div class="hidden name"><code>max_twa_parent.Rd</code></div> </div> <div class="ref-description"> <p>This function calculates maximum moving window time weighted average -concentrations (TWAs) for kinetic models fitted with <code><a href='mkinfit.html'>mkinfit</a></code>. +concentrations (TWAs) for kinetic models fitted with <code><a href="mkinfit.html">mkinfit</a></code>. Currently, only calculations for the parent are implemented for the SFO, FOMC, DFOP and HS models, using the analytical formulas given in the PEC soil section of the FOCUS guidance.</p> </div> - <pre class="usage"><span class='fu'>max_twa_parent</span><span class='op'>(</span><span class='va'>fit</span>, <span class='va'>windows</span><span class='op'>)</span> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">max_twa_parent</span><span class="op">(</span><span class="va">fit</span>, <span class="va">windows</span><span class="op">)</span> -<span class='fu'>max_twa_sfo</span><span class='op'>(</span>M0 <span class='op'>=</span> <span class='fl'>1</span>, <span class='va'>k</span>, <span class='va'>t</span><span class='op'>)</span> +<span class="fu">max_twa_sfo</span><span class="op">(</span>M0 <span class="op">=</span> <span class="fl">1</span>, <span class="va">k</span>, <span class="va">t</span><span class="op">)</span> -<span class='fu'>max_twa_fomc</span><span class='op'>(</span>M0 <span class='op'>=</span> <span class='fl'>1</span>, <span class='va'>alpha</span>, <span class='va'>beta</span>, <span class='va'>t</span><span class='op'>)</span> +<span class="fu">max_twa_fomc</span><span class="op">(</span>M0 <span class="op">=</span> <span class="fl">1</span>, <span class="va">alpha</span>, <span class="va">beta</span>, <span class="va">t</span><span class="op">)</span> -<span class='fu'>max_twa_dfop</span><span class='op'>(</span>M0 <span class='op'>=</span> <span class='fl'>1</span>, <span class='va'>k1</span>, <span class='va'>k2</span>, <span class='va'>g</span>, <span class='va'>t</span><span class='op'>)</span> +<span class="fu">max_twa_dfop</span><span class="op">(</span>M0 <span class="op">=</span> <span class="fl">1</span>, <span class="va">k1</span>, <span class="va">k2</span>, <span class="va">g</span>, <span class="va">t</span><span class="op">)</span> -<span class='fu'>max_twa_hs</span><span class='op'>(</span>M0 <span class='op'>=</span> <span class='fl'>1</span>, <span class='va'>k1</span>, <span class='va'>k2</span>, <span class='va'>tb</span>, <span class='va'>t</span><span class='op'>)</span></pre> +<span class="fu">max_twa_hs</span><span class="op">(</span>M0 <span class="op">=</span> <span class="fl">1</span>, <span class="va">k1</span>, <span class="va">k2</span>, <span class="va">tb</span>, <span class="va">t</span><span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>fit</th> - <td><p>An object of class <code><a href='mkinfit.html'>mkinfit</a></code>.</p></td> - </tr> - <tr> - <th>windows</th> - <td><p>The width of the time windows for which the TWAs should be -calculated.</p></td> - </tr> - <tr> - <th>M0</th> - <td><p>The initial concentration for which the maximum time weighted + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>fit</dt> +<dd><p>An object of class <code><a href="mkinfit.html">mkinfit</a></code>.</p></dd> +<dt>windows</dt> +<dd><p>The width of the time windows for which the TWAs should be +calculated.</p></dd> +<dt>M0</dt> +<dd><p>The initial concentration for which the maximum time weighted average over the decline curve should be calculated. The default is to use a value of 1, which means that a relative maximum time weighted average -factor (f_twa) is calculated.</p></td> - </tr> - <tr> - <th>k</th> - <td><p>The rate constant in the case of SFO kinetics.</p></td> - </tr> - <tr> - <th>t</th> - <td><p>The width of the time window.</p></td> - </tr> - <tr> - <th>alpha</th> - <td><p>Parameter of the FOMC model.</p></td> - </tr> - <tr> - <th>beta</th> - <td><p>Parameter of the FOMC model.</p></td> - </tr> - <tr> - <th>k1</th> - <td><p>The first rate constant of the DFOP or the HS kinetics.</p></td> - </tr> - <tr> - <th>k2</th> - <td><p>The second rate constant of the DFOP or the HS kinetics.</p></td> - </tr> - <tr> - <th>g</th> - <td><p>Parameter of the DFOP model.</p></td> - </tr> - <tr> - <th>tb</th> - <td><p>Parameter of the HS model.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - +factor (f_twa) is calculated.</p></dd> +<dt>k</dt> +<dd><p>The rate constant in the case of SFO kinetics.</p></dd> +<dt>t</dt> +<dd><p>The width of the time window.</p></dd> +<dt>alpha</dt> +<dd><p>Parameter of the FOMC model.</p></dd> +<dt>beta</dt> +<dd><p>Parameter of the FOMC model.</p></dd> +<dt>k1</dt> +<dd><p>The first rate constant of the DFOP or the HS kinetics.</p></dd> +<dt>k2</dt> +<dd><p>The second rate constant of the DFOP or the HS kinetics.</p></dd> +<dt>g</dt> +<dd><p>Parameter of the DFOP model.</p></dd> +<dt>tb</dt> +<dd><p>Parameter of the HS model.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>For <code>max_twa_parent</code>, a numeric vector, named using the <code>windows</code> argument. For the other functions, a numeric vector of length one (also known as 'a number').</p> - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - - <p>FOCUS (2006) “Guidance Document on Estimating Persistence + </div> + <div id="references"> + <h2>References</h2> + <p>FOCUS (2006) “Guidance Document on Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC Document Reference Sanco/10058/2005 version 2.0, 434 pp, -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> - <span class='va'>fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"FOMC"</span>, <span class='va'>FOCUS_2006_C</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - <span class='fu'>max_twa_parent</span><span class='op'>(</span><span class='va'>fit</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>7</span>, <span class='fl'>21</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> 7 21 -#> 34.71343 18.22124 </div><div class='input'> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"> <span class="va">fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"FOMC"</span>, <span class="va">FOCUS_2006_C</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu">max_twa_parent</span><span class="op">(</span><span class="va">fit</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">7</span>, <span class="fl">21</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> 7 21 </span> +<span class="r-out co"><span class="r-pr">#></span> 34.71343 18.22124 </span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/mccall81_245T-1.png b/docs/reference/mccall81_245T-1.png Binary files differindex 478462ae..79c45fe6 100644 --- a/docs/reference/mccall81_245T-1.png +++ b/docs/reference/mccall81_245T-1.png diff --git a/docs/reference/mccall81_245T.html b/docs/reference/mccall81_245T.html index 4f8d3fa0..94cd1450 100644 --- a/docs/reference/mccall81_245T.html +++ b/docs/reference/mccall81_245T.html @@ -1,69 +1,14 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Datasets on aerobic soil metabolism of 2,4,5-T in six soils — mccall81_245T • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Datasets on aerobic soil metabolism of 2,4,5-T in six soils — mccall81_245T" /> -<meta property="og:description" content="Time course of 2,4,5-trichlorophenoxyacetic acid, and the corresponding +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Datasets on aerobic soil metabolism of 2,4,5-T in six soils — mccall81_245T • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Datasets on aerobic soil metabolism of 2,4,5-T in six soils — mccall81_245T"><meta property="og:description" content="Time course of 2,4,5-trichlorophenoxyacetic acid, and the corresponding 2,4,5-trichlorophenol and 2,4,5-trichloroanisole as recovered in diethylether - extracts." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> + extracts."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -74,13 +19,12 @@ </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -89,8 +33,7 @@ <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -100,6 +43,9 @@ <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -114,30 +60,23 @@ <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Datasets on aerobic soil metabolism of 2,4,5-T in six soils</h1> @@ -151,120 +90,133 @@ extracts.</p> </div> - <pre class="usage"><span class='va'>mccall81_245T</span></pre> - - - <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="va">mccall81_245T</span></code></pre></div> + </div> - <p>A dataframe containing the following variables.</p><dl> - <dt><code>name</code></dt><dd><p>the name of the compound observed. Note that T245 is used as + <div id="format"> + <h2>Format</h2> + <p>A dataframe containing the following variables.</p><dl><dt><code>name</code></dt> +<dd><p>the name of the compound observed. Note that T245 is used as an acronym for 2,4,5-T. T245 is a legitimate object name in R, which is necessary for specifying models using - <code><a href='mkinmod.html'>mkinmod</a></code>.</p></dd> - <dt><code>time</code></dt><dd><p>a numeric vector containing sampling times in days after + <code><a href="mkinmod.html">mkinmod</a></code>.</p></dd> + + <dt><code>time</code></dt> +<dd><p>a numeric vector containing sampling times in days after treatment</p></dd> - <dt><code>value</code></dt><dd><p>a numeric vector containing concentrations in percent of applied radioactivity</p></dd> - <dt><code>soil</code></dt><dd><p>a factor containing the name of the soil</p></dd> - -</dl> - <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2> + <dt><code>value</code></dt> +<dd><p>a numeric vector containing concentrations in percent of applied radioactivity</p></dd> + + <dt><code>soil</code></dt> +<dd><p>a factor containing the name of the soil</p></dd> + +</dl></div> + <div id="source"> + <h2>Source</h2> <p>McCall P, Vrona SA, Kelley SS (1981) Fate of uniformly carbon-14 ring labelled 2,4,5-Trichlorophenoxyacetic acid and 2,4-dichlorophenoxyacetic acid. J Agric Chem 29, 100-107 - doi: <a href='https://doi.org/10.1021/jf00103a026'>10.1021/jf00103a026</a></p> + doi: <a href="https://doi.org/10.1021/jf00103a026" class="external-link">10.1021/jf00103a026</a></p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> <span class='va'>SFO_SFO_SFO</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>T245 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"phenol"</span><span class='op'>)</span>, - phenol <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"anisole"</span><span class='op'>)</span>, - anisole <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> <span class='co'># \dontrun{</span> - <span class='va'>fit.1</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO_SFO</span>, <span class='fu'><a href='https://rdrr.io/r/base/subset.html'>subset</a></span><span class='op'>(</span><span class='va'>mccall81_245T</span>, <span class='va'>soil</span> <span class='op'>==</span> <span class='st'>"Commerce"</span><span class='op'>)</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='warning'>Warning: Observations with value of zero were removed from the data</span></div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>fit.1</span><span class='op'>)</span><span class='op'>$</span><span class='va'>bpar</span> -</div><div class='output co'>#> Estimate se_notrans t value Pr(>t) -#> T245_0 1.038550e+02 2.1847074945 47.537272 4.472189e-18 -#> k_T245 4.337042e-02 0.0018983965 22.845818 2.276911e-13 -#> k_phenol 4.050581e-01 0.2986993563 1.356073 9.756989e-02 -#> k_anisole 6.678742e-03 0.0008021439 8.326114 2.623177e-07 -#> f_T245_to_phenol 6.227599e-01 0.3985340558 1.562627 6.949413e-02 -#> f_phenol_to_anisole 1.000000e+00 0.6718439825 1.488441 7.867789e-02 -#> sigma 2.514628e+00 0.4907558883 5.123989 6.233157e-05 -#> Lower Upper -#> T245_0 99.246061385 1.084640e+02 -#> k_T245 0.039631621 4.746194e-02 -#> k_phenol 0.218013879 7.525762e-01 -#> k_anisole 0.005370739 8.305299e-03 -#> f_T245_to_phenol 0.547559081 6.924813e-01 -#> f_phenol_to_anisole 0.000000000 1.000000e+00 -#> sigma 1.706607296 3.322649e+00</div><div class='input'> <span class='fu'><a href='endpoints.html'>endpoints</a></span><span class='op'>(</span><span class='va'>fit.1</span><span class='op'>)</span> -</div><div class='output co'>#> $ff -#> T245_phenol T245_sink phenol_anisole phenol_sink -#> 6.227599e-01 3.772401e-01 1.000000e+00 3.773626e-10 -#> -#> $distimes -#> DT50 DT90 -#> T245 15.982025 53.09114 -#> phenol 1.711229 5.68458 -#> anisole 103.784093 344.76329 -#> </div><div class='input'> <span class='co'># formation fraction from phenol to anisol is practically 1. As we cannot</span> - <span class='co'># fix formation fractions when using the ilr transformation, we can turn of</span> - <span class='co'># the sink in the model generation</span> - <span class='va'>SFO_SFO_SFO_2</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>T245 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"phenol"</span><span class='op'>)</span>, - phenol <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"anisole"</span>, sink <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span>, - anisole <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> <span class='va'>fit.2</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO_SFO_2</span>, <span class='fu'><a href='https://rdrr.io/r/base/subset.html'>subset</a></span><span class='op'>(</span><span class='va'>mccall81_245T</span>, <span class='va'>soil</span> <span class='op'>==</span> <span class='st'>"Commerce"</span><span class='op'>)</span>, - quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='warning'>Warning: Observations with value of zero were removed from the data</span></div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>fit.2</span><span class='op'>)</span><span class='op'>$</span><span class='va'>bpar</span> -</div><div class='output co'>#> Estimate se_notrans t value Pr(>t) Lower -#> T245_0 1.038550e+02 2.1623653066 48.028439 4.993108e-19 99.271020284 -#> k_T245 4.337042e-02 0.0018343666 23.643268 3.573556e-14 0.039650976 -#> k_phenol 4.050582e-01 0.1177237473 3.440752 1.679254e-03 0.218746587 -#> k_anisole 6.678742e-03 0.0006829745 9.778903 1.872894e-08 0.005377083 -#> f_T245_to_phenol 6.227599e-01 0.0342197875 18.198824 2.039411e-12 0.547975637 -#> sigma 2.514628e+00 0.3790944250 6.633250 2.875782e-06 1.710983655 -#> Upper -#> T245_0 108.43904074 -#> k_T245 0.04743877 -#> k_phenol 0.75005585 -#> k_anisole 0.00829550 -#> f_T245_to_phenol 0.69212308 -#> sigma 3.31827222</div><div class='input'> <span class='fu'><a href='endpoints.html'>endpoints</a></span><span class='op'>(</span><span class='va'>fit.1</span><span class='op'>)</span> -</div><div class='output co'>#> $ff -#> T245_phenol T245_sink phenol_anisole phenol_sink -#> 6.227599e-01 3.772401e-01 1.000000e+00 3.773626e-10 -#> -#> $distimes -#> DT50 DT90 -#> T245 15.982025 53.09114 -#> phenol 1.711229 5.68458 -#> anisole 103.784093 344.76329 -#> </div><div class='input'> <span class='fu'><a href='plot.mkinfit.html'>plot_sep</a></span><span class='op'>(</span><span class='va'>fit.2</span><span class='op'>)</span> -</div><div class='img'><img src='mccall81_245T-1.png' alt='' width='700' height='433' /></div><div class='input'> <span class='co'># }</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"> <span class="va">SFO_SFO_SFO</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>T245 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"phenol"</span><span class="op">)</span>,</span> +<span class="r-in"> phenol <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"anisole"</span><span class="op">)</span>,</span> +<span class="r-in"> anisole <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"> <span class="co"># \dontrun{</span></span> +<span class="r-in"> <span class="va">fit.1</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO_SFO</span>, <span class="fu"><a href="https://rdrr.io/r/base/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">mccall81_245T</span>, <span class="va">soil</span> <span class="op">==</span> <span class="st">"Commerce"</span><span class="op">)</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/summary.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">fit.1</span><span class="op">)</span><span class="op">$</span><span class="va">bpar</span></span> +<span class="r-out co"><span class="r-pr">#></span> Estimate se_notrans t value Pr(>t)</span> +<span class="r-out co"><span class="r-pr">#></span> T245_0 1.038550e+02 2.1847074945 47.537272 4.472189e-18</span> +<span class="r-out co"><span class="r-pr">#></span> k_T245 4.337042e-02 0.0018983965 22.845818 2.276911e-13</span> +<span class="r-out co"><span class="r-pr">#></span> k_phenol 4.050581e-01 0.2986993563 1.356073 9.756989e-02</span> +<span class="r-out co"><span class="r-pr">#></span> k_anisole 6.678742e-03 0.0008021439 8.326114 2.623177e-07</span> +<span class="r-out co"><span class="r-pr">#></span> f_T245_to_phenol 6.227599e-01 0.3985340558 1.562627 6.949413e-02</span> +<span class="r-out co"><span class="r-pr">#></span> f_phenol_to_anisole 1.000000e+00 0.6718439825 1.488441 7.867789e-02</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 2.514628e+00 0.4907558883 5.123989 6.233157e-05</span> +<span class="r-out co"><span class="r-pr">#></span> Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> T245_0 99.246061385 1.084640e+02</span> +<span class="r-out co"><span class="r-pr">#></span> k_T245 0.039631621 4.746194e-02</span> +<span class="r-out co"><span class="r-pr">#></span> k_phenol 0.218013879 7.525762e-01</span> +<span class="r-out co"><span class="r-pr">#></span> k_anisole 0.005370739 8.305299e-03</span> +<span class="r-out co"><span class="r-pr">#></span> f_T245_to_phenol 0.547559081 6.924813e-01</span> +<span class="r-out co"><span class="r-pr">#></span> f_phenol_to_anisole 0.000000000 1.000000e+00</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 1.706607296 3.322649e+00</span> +<span class="r-in"> <span class="fu"><a href="endpoints.html">endpoints</a></span><span class="op">(</span><span class="va">fit.1</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> $ff</span> +<span class="r-out co"><span class="r-pr">#></span> T245_phenol T245_sink phenol_anisole phenol_sink </span> +<span class="r-out co"><span class="r-pr">#></span> 6.227599e-01 3.772401e-01 1.000000e+00 3.773626e-10 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $distimes</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90</span> +<span class="r-out co"><span class="r-pr">#></span> T245 15.982025 53.09114</span> +<span class="r-out co"><span class="r-pr">#></span> phenol 1.711229 5.68458</span> +<span class="r-out co"><span class="r-pr">#></span> anisole 103.784093 344.76329</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"> <span class="co"># formation fraction from phenol to anisol is practically 1. As we cannot</span></span> +<span class="r-in"> <span class="co"># fix formation fractions when using the ilr transformation, we can turn of</span></span> +<span class="r-in"> <span class="co"># the sink in the model generation</span></span> +<span class="r-in"> <span class="va">SFO_SFO_SFO_2</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>T245 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"phenol"</span><span class="op">)</span>,</span> +<span class="r-in"> phenol <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"anisole"</span>, sink <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span>,</span> +<span class="r-in"> anisole <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"> <span class="va">fit.2</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO_SFO_2</span>, <span class="fu"><a href="https://rdrr.io/r/base/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">mccall81_245T</span>, <span class="va">soil</span> <span class="op">==</span> <span class="st">"Commerce"</span><span class="op">)</span>,</span> +<span class="r-in"> quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/summary.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">fit.2</span><span class="op">)</span><span class="op">$</span><span class="va">bpar</span></span> +<span class="r-out co"><span class="r-pr">#></span> Estimate se_notrans t value Pr(>t) Lower</span> +<span class="r-out co"><span class="r-pr">#></span> T245_0 1.038550e+02 2.1623653066 48.028439 4.993108e-19 99.271020284</span> +<span class="r-out co"><span class="r-pr">#></span> k_T245 4.337042e-02 0.0018343666 23.643268 3.573556e-14 0.039650976</span> +<span class="r-out co"><span class="r-pr">#></span> k_phenol 4.050582e-01 0.1177237473 3.440752 1.679254e-03 0.218746587</span> +<span class="r-out co"><span class="r-pr">#></span> k_anisole 6.678742e-03 0.0006829745 9.778903 1.872894e-08 0.005377083</span> +<span class="r-out co"><span class="r-pr">#></span> f_T245_to_phenol 6.227599e-01 0.0342197875 18.198824 2.039411e-12 0.547975637</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 2.514628e+00 0.3790944250 6.633250 2.875782e-06 1.710983655</span> +<span class="r-out co"><span class="r-pr">#></span> Upper</span> +<span class="r-out co"><span class="r-pr">#></span> T245_0 108.43904074</span> +<span class="r-out co"><span class="r-pr">#></span> k_T245 0.04743877</span> +<span class="r-out co"><span class="r-pr">#></span> k_phenol 0.75005585</span> +<span class="r-out co"><span class="r-pr">#></span> k_anisole 0.00829550</span> +<span class="r-out co"><span class="r-pr">#></span> f_T245_to_phenol 0.69212308</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 3.31827222</span> +<span class="r-in"> <span class="fu"><a href="endpoints.html">endpoints</a></span><span class="op">(</span><span class="va">fit.1</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> $ff</span> +<span class="r-out co"><span class="r-pr">#></span> T245_phenol T245_sink phenol_anisole phenol_sink </span> +<span class="r-out co"><span class="r-pr">#></span> 6.227599e-01 3.772401e-01 1.000000e+00 3.773626e-10 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $distimes</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90</span> +<span class="r-out co"><span class="r-pr">#></span> T245 15.982025 53.09114</span> +<span class="r-out co"><span class="r-pr">#></span> phenol 1.711229 5.68458</span> +<span class="r-out co"><span class="r-pr">#></span> anisole 103.784093 344.76329</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"> <span class="fu"><a href="plot.mkinfit.html">plot_sep</a></span><span class="op">(</span><span class="va">fit.2</span><span class="op">)</span></span> +<span class="r-plt img"><img src="mccall81_245T-1.png" alt="" width="700" height="433"></span> +<span class="r-in"> <span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/mean_degparms.html b/docs/reference/mean_degparms.html new file mode 100644 index 00000000..c31e310c --- /dev/null +++ b/docs/reference/mean_degparms.html @@ -0,0 +1,138 @@ +<!DOCTYPE html> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Calculate mean degradation parameters for an mmkin row object — mean_degparms • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Calculate mean degradation parameters for an mmkin row object — mean_degparms"><meta property="og:description" content="Calculate mean degradation parameters for an mmkin row object"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> +<script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> +<script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + + + <div class="container template-reference-topic"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <div class="container"> + <div class="navbar-header"> + <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> + <span class="sr-only">Toggle navigation</span> + <span class="icon-bar"></span> + <span class="icon-bar"></span> + <span class="icon-bar"></span> + </button> + <span class="navbar-brand"> + <a class="navbar-link" href="../index.html">mkin</a> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> + </span> + </div> + + <div id="navbar" class="navbar-collapse collapse"> + <ul class="nav navbar-nav"><li> + <a href="../reference/index.html">Functions and data</a> +</li> +<li class="dropdown"> + <a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-expanded="false"> + Articles + + <span class="caret"></span> + </a> + <ul class="dropdown-menu" role="menu"><li> + <a href="../articles/mkin.html">Introduction to mkin</a> + </li> + <li> + <a href="../articles/FOCUS_D.html">Example evaluation of FOCUS Example Dataset D</a> + </li> + <li> + <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> + </li> + <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> + <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> + </li> + <li> + <a href="../articles/web_only/compiled_models.html">Performance benefit by using compiled model definitions in mkin</a> + </li> + <li> + <a href="../articles/twa.html">Calculation of time weighted average concentrations with mkin</a> + </li> + <li> + <a href="../articles/web_only/NAFTA_examples.html">Example evaluation of NAFTA SOP Attachment examples</a> + </li> + <li> + <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> + </li> + </ul></li> +<li> + <a href="../news/index.html">News</a> +</li> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> + <span class="fab fa-github fa-lg"></span> + + </a> +</li> + </ul></div><!--/.nav-collapse --> + </div><!--/.container --> +</div><!--/.navbar --> + + + + </header><div class="row"> + <div class="col-md-9 contents"> + <div class="page-header"> + <h1>Calculate mean degradation parameters for an mmkin row object</h1> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/mean_degparms.R" class="external-link"><code>R/mean_degparms.R</code></a></small> + <div class="hidden name"><code>mean_degparms.Rd</code></div> + </div> + + <div class="ref-description"> + <p>Calculate mean degradation parameters for an mmkin row object</p> + </div> + + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">mean_degparms</span><span class="op">(</span><span class="va">object</span>, random <span class="op">=</span> <span class="cn">FALSE</span>, test_log_parms <span class="op">=</span> <span class="cn">FALSE</span>, conf.level <span class="op">=</span> <span class="fl">0.6</span><span class="op">)</span></code></pre></div> + </div> + + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>An mmkin row object containing several fits of the same model to different datasets</p></dd> +<dt>random</dt> +<dd><p>Should a list with fixed and random effects be returned?</p></dd> +<dt>test_log_parms</dt> +<dd><p>If TRUE, log parameters are only considered in +the mean calculations if their untransformed counterparts (most likely +rate constants) pass the t-test for significant difference from zero.</p></dd> +<dt>conf.level</dt> +<dd><p>Possibility to adjust the required confidence level +for parameter that are tested if requested by 'test_log_parms'.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>If random is FALSE (default), a named vector containing mean values +of the fitted degradation model parameters. If random is TRUE, a list with +fixed and random effects, in the format required by the start argument of +nlme for the case of a single grouping variable ds.</p> + </div> + + </div> + <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> +</div> + + + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> +</div> + +<div class="pkgdown"> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> +</div> + + </footer></div> + + + + + + + </body></html> + diff --git a/docs/reference/mixed-1.png b/docs/reference/mixed-1.png Binary files differindex 422ab6a0..54b81b70 100644 --- a/docs/reference/mixed-1.png +++ b/docs/reference/mixed-1.png diff --git a/docs/reference/mixed.html b/docs/reference/mixed.html index b3bf35bf..dc0d1681 100644 --- a/docs/reference/mixed.html +++ b/docs/reference/mixed.html @@ -1,67 +1,12 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Create a mixed effects model from an mmkin row object — mixed • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Create a mixed effects model from an mmkin row object — mixed" /> -<meta property="og:description" content="Create a mixed effects model from an mmkin row object" /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Create a mixed effects model from an mmkin row object — mixed • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Create a mixed effects model from an mmkin row object — mixed"><meta property="og:description" content="Create a mixed effects model from an mmkin row object"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -72,13 +17,12 @@ </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.5</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -87,8 +31,7 @@ <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -98,6 +41,9 @@ <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -112,34 +58,27 @@ <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Create a mixed effects model from an mmkin row object</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/mixed.mmkin.R'><code>R/mixed.mmkin.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/mixed.mmkin.R" class="external-link"><code>R/mixed.mmkin.R</code></a></small> <div class="hidden name"><code>mixed.Rd</code></div> </div> @@ -147,131 +86,126 @@ <p>Create a mixed effects model from an mmkin row object</p> </div> - <pre class="usage"><span class='fu'>mixed</span><span class='op'>(</span><span class='va'>object</span>, <span class='va'>...</span><span class='op'>)</span> - -<span class='co'># S3 method for mmkin</span> -<span class='fu'>mixed</span><span class='op'>(</span><span class='va'>object</span>, method <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"none"</span><span class='op'>)</span>, <span class='va'>...</span><span class='op'>)</span> - -<span class='co'># S3 method for mixed.mmkin</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>x</span>, digits <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/Extremes.html'>max</a></span><span class='op'>(</span><span class='fl'>3</span>, <span class='fu'><a href='https://rdrr.io/r/base/options.html'>getOption</a></span><span class='op'>(</span><span class='st'>"digits"</span><span class='op'>)</span> <span class='op'>-</span> <span class='fl'>3</span><span class='op'>)</span>, <span class='va'>...</span><span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">mixed</span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span><span class="op">)</span> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>An <a href='mmkin.html'>mmkin</a> row object</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Currently not used</p></td> - </tr> - <tr> - <th>method</th> - <td><p>The method to be used</p></td> - </tr> - <tr> - <th>x</th> - <td><p>A mixed.mmkin object to print</p></td> - </tr> - <tr> - <th>digits</th> - <td><p>Number of digits to use for printing.</p></td> - </tr> - </table> +<span class="co"># S3 method for mmkin</span> +<span class="fu">mixed</span><span class="op">(</span><span class="va">object</span>, method <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"none"</span><span class="op">)</span>, <span class="va">...</span><span class="op">)</span> +<span class="co"># S3 method for mixed.mmkin</span> +<span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">x</span>, digits <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/Extremes.html" class="external-link">max</a></span><span class="op">(</span><span class="fl">3</span>, <span class="fu"><a href="https://rdrr.io/r/base/options.html" class="external-link">getOption</a></span><span class="op">(</span><span class="st">"digits"</span><span class="op">)</span> <span class="op">-</span> <span class="fl">3</span><span class="op">)</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='va'>sampling_times</span> <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>1</span>, <span class='fl'>3</span>, <span class='fl'>7</span>, <span class='fl'>14</span>, <span class='fl'>28</span>, <span class='fl'>60</span>, <span class='fl'>90</span>, <span class='fl'>120</span><span class='op'>)</span> -<span class='va'>n_biphasic</span> <span class='op'><-</span> <span class='fl'>8</span> -<span class='va'>err_1</span> <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>const <span class='op'>=</span> <span class='fl'>1</span>, prop <span class='op'>=</span> <span class='fl'>0.07</span><span class='op'>)</span> - -<span class='va'>DFOP_SFO</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"DFOP"</span>, <span class='st'>"m1"</span><span class='op'>)</span>, - m1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, - quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - -<span class='fu'><a href='https://rdrr.io/r/base/Random.html'>set.seed</a></span><span class='op'>(</span><span class='fl'>123456</span><span class='op'>)</span> -<span class='va'>log_sd</span> <span class='op'><-</span> <span class='fl'>0.3</span> -<span class='va'>syn_biphasic_parms</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/matrix.html'>as.matrix</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/data.frame.html'>data.frame</a></span><span class='op'>(</span> - k1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/stats/Lognormal.html'>rlnorm</a></span><span class='op'>(</span><span class='va'>n_biphasic</span>, <span class='fu'><a href='https://rdrr.io/r/base/Log.html'>log</a></span><span class='op'>(</span><span class='fl'>0.05</span><span class='op'>)</span>, <span class='va'>log_sd</span><span class='op'>)</span>, - k2 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/stats/Lognormal.html'>rlnorm</a></span><span class='op'>(</span><span class='va'>n_biphasic</span>, <span class='fu'><a href='https://rdrr.io/r/base/Log.html'>log</a></span><span class='op'>(</span><span class='fl'>0.01</span><span class='op'>)</span>, <span class='va'>log_sd</span><span class='op'>)</span>, - g <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/stats/Logistic.html'>plogis</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/stats/Normal.html'>rnorm</a></span><span class='op'>(</span><span class='va'>n_biphasic</span>, <span class='fl'>0</span>, <span class='va'>log_sd</span><span class='op'>)</span><span class='op'>)</span>, - f_parent_to_m1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/stats/Logistic.html'>plogis</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/stats/Normal.html'>rnorm</a></span><span class='op'>(</span><span class='va'>n_biphasic</span>, <span class='fl'>0</span>, <span class='va'>log_sd</span><span class='op'>)</span><span class='op'>)</span>, - k_m1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/stats/Lognormal.html'>rlnorm</a></span><span class='op'>(</span><span class='va'>n_biphasic</span>, <span class='fu'><a href='https://rdrr.io/r/base/Log.html'>log</a></span><span class='op'>(</span><span class='fl'>0.002</span><span class='op'>)</span>, <span class='va'>log_sd</span><span class='op'>)</span><span class='op'>)</span><span class='op'>)</span> - -<span class='va'>ds_biphasic_mean</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/lapply.html'>lapply</a></span><span class='op'>(</span><span class='fl'>1</span><span class='op'>:</span><span class='va'>n_biphasic</span>, - <span class='kw'>function</span><span class='op'>(</span><span class='va'>i</span><span class='op'>)</span> <span class='op'>{</span> - <span class='fu'><a href='mkinpredict.html'>mkinpredict</a></span><span class='op'>(</span><span class='va'>DFOP_SFO</span>, <span class='va'>syn_biphasic_parms</span><span class='op'>[</span><span class='va'>i</span>, <span class='op'>]</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>100</span>, m1 <span class='op'>=</span> <span class='fl'>0</span><span class='op'>)</span>, <span class='va'>sampling_times</span><span class='op'>)</span> - <span class='op'>}</span> -<span class='op'>)</span> - -<span class='fu'><a href='https://rdrr.io/r/base/Random.html'>set.seed</a></span><span class='op'>(</span><span class='fl'>123456L</span><span class='op'>)</span> -<span class='va'>ds_biphasic</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/lapply.html'>lapply</a></span><span class='op'>(</span><span class='va'>ds_biphasic_mean</span>, <span class='kw'>function</span><span class='op'>(</span><span class='va'>ds</span><span class='op'>)</span> <span class='op'>{</span> - <span class='fu'><a href='add_err.html'>add_err</a></span><span class='op'>(</span><span class='va'>ds</span>, - sdfunc <span class='op'>=</span> <span class='kw'>function</span><span class='op'>(</span><span class='va'>value</span><span class='op'>)</span> <span class='fu'><a href='https://rdrr.io/r/base/MathFun.html'>sqrt</a></span><span class='op'>(</span><span class='va'>err_1</span><span class='op'>$</span><span class='va'>const</span><span class='op'>^</span><span class='fl'>2</span> <span class='op'>+</span> <span class='va'>value</span><span class='op'>^</span><span class='fl'>2</span> <span class='op'>*</span> <span class='va'>err_1</span><span class='op'>$</span><span class='va'>prop</span><span class='op'>^</span><span class='fl'>2</span><span class='op'>)</span>, - n <span class='op'>=</span> <span class='fl'>1</span>, secondary <span class='op'>=</span> <span class='st'>"m1"</span><span class='op'>)</span><span class='op'>[[</span><span class='fl'>1</span><span class='op'>]</span><span class='op'>]</span> -<span class='op'>}</span><span class='op'>)</span> - -<span class='co'># \dontrun{</span> -<span class='va'>f_mmkin</span> <span class='op'><-</span> <span class='fu'><a href='mmkin.html'>mmkin</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span><span class='st'>"DFOP-SFO"</span> <span class='op'>=</span> <span class='va'>DFOP_SFO</span><span class='op'>)</span>, <span class='va'>ds_biphasic</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>An <a href="mmkin.html">mmkin</a> row object</p></dd> +<dt>...</dt> +<dd><p>Currently not used</p></dd> +<dt>method</dt> +<dd><p>The method to be used</p></dd> +<dt>x</dt> +<dd><p>A mixed.mmkin object to print</p></dd> +<dt>digits</dt> +<dd><p>Number of digits to use for printing.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>An object of class 'mixed.mmkin' which has the observed data in a +single dataframe which is convenient for plotting</p> + </div> -<span class='va'>f_mixed</span> <span class='op'><-</span> <span class='fu'>mixed</span><span class='op'>(</span><span class='va'>f_mmkin</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>f_mixed</span><span class='op'>)</span> -</div><div class='output co'>#> Kinetic model fitted by nonlinear regression to each dataset -#> Structural model: -#> d_parent/dt = - ((k1 * g * exp(-k1 * time) + k2 * (1 - g) * exp(-k2 * -#> time)) / (g * exp(-k1 * time) + (1 - g) * exp(-k2 * time))) -#> * parent -#> d_m1/dt = + f_parent_to_m1 * ((k1 * g * exp(-k1 * time) + k2 * (1 - g) -#> * exp(-k2 * time)) / (g * exp(-k1 * time) + (1 - g) * -#> exp(-k2 * time))) * parent - k_m1 * m1 -#> -#> Data: -#> 271 observations of 2 variable(s) grouped in 8 datasets -#> -#> <mmkin> object -#> Status of individual fits: -#> -#> dataset -#> model 1 2 3 4 5 6 7 8 -#> DFOP-SFO OK OK OK OK OK OK OK OK -#> -#> OK: No warnings -#> -#> Mean fitted parameters: -#> parent_0 log_k_m1 f_parent_qlogis log_k1 log_k2 -#> 100.674757 -8.761916 -0.004347 -3.348812 -3.986853 -#> g_qlogis -#> -0.087392 </div><div class='input'><span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>f_mixed</span><span class='op'>)</span> -</div><div class='img'><img src='mixed-1.png' alt='' width='700' height='433' /></div><div class='input'><span class='co'># }</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="va">sampling_times</span> <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">1</span>, <span class="fl">3</span>, <span class="fl">7</span>, <span class="fl">14</span>, <span class="fl">28</span>, <span class="fl">60</span>, <span class="fl">90</span>, <span class="fl">120</span><span class="op">)</span></span> +<span class="r-in"><span class="va">n_biphasic</span> <span class="op"><-</span> <span class="fl">8</span></span> +<span class="r-in"><span class="va">err_1</span> <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>const <span class="op">=</span> <span class="fl">1</span>, prop <span class="op">=</span> <span class="fl">0.07</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">DFOP_SFO</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="st">"m1"</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/Random.html" class="external-link">set.seed</a></span><span class="op">(</span><span class="fl">123456</span><span class="op">)</span></span> +<span class="r-in"><span class="va">log_sd</span> <span class="op"><-</span> <span class="fl">0.3</span></span> +<span class="r-in"><span class="va">syn_biphasic_parms</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/matrix.html" class="external-link">as.matrix</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/data.frame.html" class="external-link">data.frame</a></span><span class="op">(</span></span> +<span class="r-in"> k1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/stats/Lognormal.html" class="external-link">rlnorm</a></span><span class="op">(</span><span class="va">n_biphasic</span>, <span class="fu"><a href="https://rdrr.io/r/base/Log.html" class="external-link">log</a></span><span class="op">(</span><span class="fl">0.05</span><span class="op">)</span>, <span class="va">log_sd</span><span class="op">)</span>,</span> +<span class="r-in"> k2 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/stats/Lognormal.html" class="external-link">rlnorm</a></span><span class="op">(</span><span class="va">n_biphasic</span>, <span class="fu"><a href="https://rdrr.io/r/base/Log.html" class="external-link">log</a></span><span class="op">(</span><span class="fl">0.01</span><span class="op">)</span>, <span class="va">log_sd</span><span class="op">)</span>,</span> +<span class="r-in"> g <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/stats/Logistic.html" class="external-link">plogis</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/stats/Normal.html" class="external-link">rnorm</a></span><span class="op">(</span><span class="va">n_biphasic</span>, <span class="fl">0</span>, <span class="va">log_sd</span><span class="op">)</span><span class="op">)</span>,</span> +<span class="r-in"> f_parent_to_m1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/stats/Logistic.html" class="external-link">plogis</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/stats/Normal.html" class="external-link">rnorm</a></span><span class="op">(</span><span class="va">n_biphasic</span>, <span class="fl">0</span>, <span class="va">log_sd</span><span class="op">)</span><span class="op">)</span>,</span> +<span class="r-in"> k_m1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/stats/Lognormal.html" class="external-link">rlnorm</a></span><span class="op">(</span><span class="va">n_biphasic</span>, <span class="fu"><a href="https://rdrr.io/r/base/Log.html" class="external-link">log</a></span><span class="op">(</span><span class="fl">0.002</span><span class="op">)</span>, <span class="va">log_sd</span><span class="op">)</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">ds_biphasic_mean</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="fl">1</span><span class="op">:</span><span class="va">n_biphasic</span>,</span> +<span class="r-in"> <span class="kw">function</span><span class="op">(</span><span class="va">i</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="fu"><a href="mkinpredict.html">mkinpredict</a></span><span class="op">(</span><span class="va">DFOP_SFO</span>, <span class="va">syn_biphasic_parms</span><span class="op">[</span><span class="va">i</span>, <span class="op">]</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span>, m1 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span>, <span class="va">sampling_times</span><span class="op">)</span></span> +<span class="r-in"> <span class="op">}</span></span> +<span class="r-in"><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/Random.html" class="external-link">set.seed</a></span><span class="op">(</span><span class="fl">123456L</span><span class="op">)</span></span> +<span class="r-in"><span class="va">ds_biphasic</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="va">ds_biphasic_mean</span>, <span class="kw">function</span><span class="op">(</span><span class="va">ds</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="fu"><a href="add_err.html">add_err</a></span><span class="op">(</span><span class="va">ds</span>,</span> +<span class="r-in"> sdfunc <span class="op">=</span> <span class="kw">function</span><span class="op">(</span><span class="va">value</span><span class="op">)</span> <span class="fu"><a href="https://rdrr.io/r/base/MathFun.html" class="external-link">sqrt</a></span><span class="op">(</span><span class="va">err_1</span><span class="op">$</span><span class="va">const</span><span class="op">^</span><span class="fl">2</span> <span class="op">+</span> <span class="va">value</span><span class="op">^</span><span class="fl">2</span> <span class="op">*</span> <span class="va">err_1</span><span class="op">$</span><span class="va">prop</span><span class="op">^</span><span class="fl">2</span><span class="op">)</span>,</span> +<span class="r-in"> n <span class="op">=</span> <span class="fl">1</span>, secondary <span class="op">=</span> <span class="st">"m1"</span><span class="op">)</span><span class="op">[[</span><span class="fl">1</span><span class="op">]</span><span class="op">]</span></span> +<span class="r-in"><span class="op">}</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="va">f_mmkin</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="st">"DFOP-SFO"</span> <span class="op">=</span> <span class="va">DFOP_SFO</span><span class="op">)</span>, <span class="va">ds_biphasic</span>, error_model <span class="op">=</span> <span class="st">"tc"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">f_mixed</span> <span class="op"><-</span> <span class="fu">mixed</span><span class="op">(</span><span class="va">f_mmkin</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">f_mixed</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Kinetic model fitted by nonlinear regression to each dataset</span> +<span class="r-out co"><span class="r-pr">#></span> Structural model:</span> +<span class="r-out co"><span class="r-pr">#></span> d_parent/dt = - ((k1 * g * exp(-k1 * time) + k2 * (1 - g) * exp(-k2 *</span> +<span class="r-out co"><span class="r-pr">#></span> time)) / (g * exp(-k1 * time) + (1 - g) * exp(-k2 * time)))</span> +<span class="r-out co"><span class="r-pr">#></span> * parent</span> +<span class="r-out co"><span class="r-pr">#></span> d_m1/dt = + f_parent_to_m1 * ((k1 * g * exp(-k1 * time) + k2 * (1 - g)</span> +<span class="r-out co"><span class="r-pr">#></span> * exp(-k2 * time)) / (g * exp(-k1 * time) + (1 - g) *</span> +<span class="r-out co"><span class="r-pr">#></span> exp(-k2 * time))) * parent - k_m1 * m1</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Data:</span> +<span class="r-out co"><span class="r-pr">#></span> 271 observations of 2 variable(s) grouped in 8 datasets</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> <mmkin> object</span> +<span class="r-out co"><span class="r-pr">#></span> Status of individual fits:</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> dataset</span> +<span class="r-out co"><span class="r-pr">#></span> model 1 2 3 4 5 6 7 8 </span> +<span class="r-out co"><span class="r-pr">#></span> DFOP-SFO OK OK OK OK OK OK OK OK</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> OK: No warnings</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Mean fitted parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_k_m1 f_parent_qlogis log_k1 log_k2 </span> +<span class="r-out co"><span class="r-pr">#></span> 100.674757 -8.761916 -0.004347 -3.348812 -3.986853 </span> +<span class="r-out co"><span class="r-pr">#></span> g_qlogis </span> +<span class="r-out co"><span class="r-pr">#></span> -0.087392 </span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_mixed</span><span class="op">)</span></span> +<span class="r-plt img"><img src="mixed-1.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/mkin_long_to_wide.html b/docs/reference/mkin_long_to_wide.html index c82da5dd..be37f095 100644 --- a/docs/reference/mkin_long_to_wide.html +++ b/docs/reference/mkin_long_to_wide.html @@ -1,69 +1,14 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Convert a dataframe from long to wide format — mkin_long_to_wide • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Convert a dataframe from long to wide format — mkin_long_to_wide" /> -<meta property="og:description" content="This function takes a dataframe in the long form, i.e. with a row for each +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Convert a dataframe from long to wide format — mkin_long_to_wide • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Convert a dataframe from long to wide format — mkin_long_to_wide"><meta property="og:description" content="This function takes a dataframe in the long form, i.e. with a row for each observed value, and converts it into a dataframe with one independent -variable and several dependent variables as columns." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +variable and several dependent variables as columns."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -74,13 +19,12 @@ variable and several dependent variables as columns." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -89,8 +33,7 @@ variable and several dependent variables as columns." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -100,6 +43,9 @@ variable and several dependent variables as columns." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -114,34 +60,27 @@ variable and several dependent variables as columns." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Convert a dataframe from long to wide format</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/mkin_long_to_wide.R'><code>R/mkin_long_to_wide.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/mkin_long_to_wide.R" class="external-link"><code>R/mkin_long_to_wide.R</code></a></small> <div class="hidden name"><code>mkin_long_to_wide.Rd</code></div> </div> @@ -151,87 +90,82 @@ observed value, and converts it into a dataframe with one independent variable and several dependent variables as columns.</p> </div> - <pre class="usage"><span class='fu'>mkin_long_to_wide</span><span class='op'>(</span><span class='va'>long_data</span>, time <span class='op'>=</span> <span class='st'>"time"</span>, outtime <span class='op'>=</span> <span class='st'>"time"</span><span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">mkin_long_to_wide</span><span class="op">(</span><span class="va">long_data</span>, time <span class="op">=</span> <span class="st">"time"</span>, outtime <span class="op">=</span> <span class="st">"time"</span><span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>long_data</th> - <td><p>The dataframe must contain one variable called "time" with + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>long_data</dt> +<dd><p>The dataframe must contain one variable called "time" with the time values specified by the <code>time</code> argument, one column called "name" with the grouping of the observed values, and finally one column of -observed values called "value".</p></td> - </tr> - <tr> - <th>time</th> - <td><p>The name of the time variable in the long input data.</p></td> - </tr> - <tr> - <th>outtime</th> - <td><p>The name of the time variable in the wide output data.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - +observed values called "value".</p></dd> +<dt>time</dt> +<dd><p>The name of the time variable in the long input data.</p></dd> +<dt>outtime</dt> +<dd><p>The name of the time variable in the wide output data.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>Dataframe in wide format.</p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='fu'>mkin_long_to_wide</span><span class='op'>(</span><span class='va'>FOCUS_2006_D</span><span class='op'>)</span> -</div><div class='output co'>#> time parent m1 -#> 1 0 99.46 0.00 -#> 2 0 102.04 0.00 -#> 3 1 93.50 4.84 -#> 4 1 92.50 5.64 -#> 5 3 63.23 12.91 -#> 6 3 68.99 12.96 -#> 7 7 52.32 22.97 -#> 8 7 55.13 24.47 -#> 9 14 27.27 41.69 -#> 10 14 26.64 33.21 -#> 11 21 11.50 44.37 -#> 12 21 11.64 46.44 -#> 13 35 2.85 41.22 -#> 14 35 2.91 37.95 -#> 15 50 0.69 41.19 -#> 16 50 0.63 40.01 -#> 17 75 0.05 40.09 -#> 18 75 0.06 33.85 -#> 19 100 NA 31.04 -#> 20 100 NA 33.13 -#> 21 120 NA 25.15 -#> 22 120 NA 33.31</div><div class='input'> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="fu">mkin_long_to_wide</span><span class="op">(</span><span class="va">FOCUS_2006_D</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> time parent m1</span> +<span class="r-out co"><span class="r-pr">#></span> 1 0 99.46 0.00</span> +<span class="r-out co"><span class="r-pr">#></span> 2 0 102.04 0.00</span> +<span class="r-out co"><span class="r-pr">#></span> 3 1 93.50 4.84</span> +<span class="r-out co"><span class="r-pr">#></span> 4 1 92.50 5.64</span> +<span class="r-out co"><span class="r-pr">#></span> 5 3 63.23 12.91</span> +<span class="r-out co"><span class="r-pr">#></span> 6 3 68.99 12.96</span> +<span class="r-out co"><span class="r-pr">#></span> 7 7 52.32 22.97</span> +<span class="r-out co"><span class="r-pr">#></span> 8 7 55.13 24.47</span> +<span class="r-out co"><span class="r-pr">#></span> 9 14 27.27 41.69</span> +<span class="r-out co"><span class="r-pr">#></span> 10 14 26.64 33.21</span> +<span class="r-out co"><span class="r-pr">#></span> 11 21 11.50 44.37</span> +<span class="r-out co"><span class="r-pr">#></span> 12 21 11.64 46.44</span> +<span class="r-out co"><span class="r-pr">#></span> 13 35 2.85 41.22</span> +<span class="r-out co"><span class="r-pr">#></span> 14 35 2.91 37.95</span> +<span class="r-out co"><span class="r-pr">#></span> 15 50 0.69 41.19</span> +<span class="r-out co"><span class="r-pr">#></span> 16 50 0.63 40.01</span> +<span class="r-out co"><span class="r-pr">#></span> 17 75 0.05 40.09</span> +<span class="r-out co"><span class="r-pr">#></span> 18 75 0.06 33.85</span> +<span class="r-out co"><span class="r-pr">#></span> 19 100 NA 31.04</span> +<span class="r-out co"><span class="r-pr">#></span> 20 100 NA 33.13</span> +<span class="r-out co"><span class="r-pr">#></span> 21 120 NA 25.15</span> +<span class="r-out co"><span class="r-pr">#></span> 22 120 NA 33.31</span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/mkin_wide_to_long.html b/docs/reference/mkin_wide_to_long.html index 15619fba..06bea7e7 100644 --- a/docs/reference/mkin_wide_to_long.html +++ b/docs/reference/mkin_wide_to_long.html @@ -1,69 +1,14 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Convert a dataframe with observations over time into long format — mkin_wide_to_long • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Convert a dataframe with observations over time into long format — mkin_wide_to_long" /> -<meta property="og:description" content="This function simply takes a dataframe with one independent variable and +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Convert a dataframe with observations over time into long format — mkin_wide_to_long • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Convert a dataframe with observations over time into long format — mkin_wide_to_long"><meta property="og:description" content="This function simply takes a dataframe with one independent variable and several dependent variable and converts it into the long form as required by -mkinfit." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +mkinfit."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -74,13 +19,12 @@ mkinfit." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -89,8 +33,7 @@ mkinfit." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -100,6 +43,9 @@ mkinfit." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -114,104 +60,94 @@ mkinfit." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Convert a dataframe with observations over time into long format</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/mkin_wide_to_long.R'><code>R/mkin_wide_to_long.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/mkin_wide_to_long.R" class="external-link"><code>R/mkin_wide_to_long.R</code></a></small> <div class="hidden name"><code>mkin_wide_to_long.Rd</code></div> </div> <div class="ref-description"> <p>This function simply takes a dataframe with one independent variable and several dependent variable and converts it into the long form as required by -<code><a href='mkinfit.html'>mkinfit</a></code>.</p> +<code><a href="mkinfit.html">mkinfit</a></code>.</p> </div> - <pre class="usage"><span class='fu'>mkin_wide_to_long</span><span class='op'>(</span><span class='va'>wide_data</span>, time <span class='op'>=</span> <span class='st'>"t"</span><span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">mkin_wide_to_long</span><span class="op">(</span><span class="va">wide_data</span>, time <span class="op">=</span> <span class="st">"t"</span><span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>wide_data</th> - <td><p>The dataframe must contain one variable with the time + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>wide_data</dt> +<dd><p>The dataframe must contain one variable with the time values specified by the <code>time</code> argument and usually more than one -column of observed values.</p></td> - </tr> - <tr> - <th>time</th> - <td><p>The name of the time variable.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - - <p>Dataframe in long format as needed for <code><a href='mkinfit.html'>mkinfit</a></code>.</p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - +column of observed values.</p></dd> +<dt>time</dt> +<dd><p>The name of the time variable.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>Dataframe in long format as needed for <code><a href="mkinfit.html">mkinfit</a></code>.</p> + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='va'>wide</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/data.frame.html'>data.frame</a></span><span class='op'>(</span>t <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>1</span>,<span class='fl'>2</span>,<span class='fl'>3</span><span class='op'>)</span>, x <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>1</span>,<span class='fl'>4</span>,<span class='fl'>7</span><span class='op'>)</span>, y <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>3</span>,<span class='fl'>4</span>,<span class='fl'>5</span><span class='op'>)</span><span class='op'>)</span> -<span class='fu'>mkin_wide_to_long</span><span class='op'>(</span><span class='va'>wide</span><span class='op'>)</span> -</div><div class='output co'>#> name time value -#> 1 x 1 1 -#> 2 x 2 4 -#> 3 x 3 7 -#> 4 y 1 3 -#> 5 y 2 4 -#> 6 y 3 5</div><div class='input'> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="va">wide</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/data.frame.html" class="external-link">data.frame</a></span><span class="op">(</span>t <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">1</span>,<span class="fl">2</span>,<span class="fl">3</span><span class="op">)</span>, x <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">1</span>,<span class="fl">4</span>,<span class="fl">7</span><span class="op">)</span>, y <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">3</span>,<span class="fl">4</span>,<span class="fl">5</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="fu">mkin_wide_to_long</span><span class="op">(</span><span class="va">wide</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> name time value</span> +<span class="r-out co"><span class="r-pr">#></span> 1 x 1 1</span> +<span class="r-out co"><span class="r-pr">#></span> 2 x 2 4</span> +<span class="r-out co"><span class="r-pr">#></span> 3 x 3 7</span> +<span class="r-out co"><span class="r-pr">#></span> 4 y 1 3</span> +<span class="r-out co"><span class="r-pr">#></span> 5 y 2 4</span> +<span class="r-out co"><span class="r-pr">#></span> 6 y 3 5</span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/mkinds.html b/docs/reference/mkinds.html index fe89012c..25edbf38 100644 --- a/docs/reference/mkinds.html +++ b/docs/reference/mkinds.html @@ -1,70 +1,15 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>A dataset class for mkin — mkinds • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="A dataset class for mkin — mkinds" /> -<meta property="og:description" content="At the moment this dataset class is hardly used in mkin. For example, +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>A dataset class for mkin — mkinds • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="A dataset class for mkin — mkinds"><meta property="og:description" content="At the moment this dataset class is hardly used in mkin. For example, mkinfit does not take mkinds datasets as argument, but works with dataframes such as the on contained in the data field of mkinds objects. Some datasets -provided by this package come as mkinds objects nevertheless." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +provided by this package come as mkinds objects nevertheless."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -75,13 +20,12 @@ provided by this package come as mkinds objects nevertheless." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -90,8 +34,7 @@ provided by this package come as mkinds objects nevertheless." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -101,6 +44,9 @@ provided by this package come as mkinds objects nevertheless." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -115,34 +61,27 @@ provided by this package come as mkinds objects nevertheless." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>A dataset class for mkin</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/mkinds.R'><code>R/mkinds.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/mkinds.R" class="external-link"><code>R/mkinds.R</code></a></small> <div class="hidden name"><code>mkinds.Rd</code></div> </div> @@ -153,118 +92,143 @@ such as the on contained in the data field of mkinds objects. Some datasets provided by this package come as mkinds objects nevertheless.</p> </div> - <pre class="usage"><span class='co'># S3 method for mkinds</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>x</span>, data <span class='op'>=</span> <span class='cn'>FALSE</span>, <span class='va'>...</span><span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for mkinds</span> +<span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">x</span>, data <span class="op">=</span> <span class="cn">FALSE</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>x</dt> +<dd><p>An mkinds object.</p></dd> +<dt>data</dt> +<dd><p>Should the data be printed?</p></dd> +<dt>...</dt> +<dd><p>Not used.</p></dd> +</dl></div> + <div id="public-fields"> + <h2>Public fields</h2> + <p></p><div class="r6-fields"><dl><dt><code>title</code></dt> +<dd><p>A full title for the dataset</p></dd> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>x</th> - <td><p>An mkinds object.</p></td> - </tr> - <tr> - <th>data</th> - <td><p>Should the data be printed?</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Not used.</p></td> - </tr> - </table> - <h2 class="hasAnchor" id="public-fields"><a class="anchor" href="#public-fields"></a>Public fields</h2> +<dt><code>sampling_times</code></dt> +<dd><p>The sampling times</p></dd> - <p><div class="r6-fields"></p><dl> -<dt><code>title</code></dt><dd><p>A full title for the dataset</p></dd> -<dt><code>sampling_times</code></dt><dd><p>The sampling times</p></dd> +<dt><code>time_unit</code></dt> +<dd><p>The time unit</p></dd> -<dt><code>time_unit</code></dt><dd><p>The time unit</p></dd> -<dt><code>observed</code></dt><dd><p>Names of the observed variables</p></dd> +<dt><code>observed</code></dt> +<dd><p>Names of the observed variables</p></dd> -<dt><code>unit</code></dt><dd><p>The unit of the observations</p></dd> -<dt><code>replicates</code></dt><dd><p>The maximum number of replicates per sampling time</p></dd> +<dt><code>unit</code></dt> +<dd><p>The unit of the observations</p></dd> -<dt><code>data</code></dt><dd><p>A data frame with at least the columns name, time + +<dt><code>replicates</code></dt> +<dd><p>The maximum number of replicates per sampling time</p></dd> + + +<dt><code>data</code></dt> +<dd><p>A data frame with at least the columns name, time and value in order to be compatible with mkinfit</p></dd> -</dl><p></div></p> - <h2 class="hasAnchor" id="methods"><a class="anchor" href="#methods"></a>Methods</h2> +</dl><p></p></div> + </div> + <div id="methods"> + <h2>Methods</h2> -<h3 class='hasAnchor' id='arguments'><a class='anchor' href='#arguments'></a>Public methods</h3> +<div class="section"> +<h3 id="public-methods">Public methods<a class="anchor" aria-label="anchor" href="#public-methods"></a></h3> + +<ul><li><p><a href="#method-new"><code>mkinds$new()</code></a></p></li> +<li><p><a href="#method-clone"><code>mkinds$clone()</code></a></p></li> +</ul></div><p></p><hr><a id="method-new"></a><div class="section"> +<h3 id="method-new-">Method <code>new()</code><a class="anchor" aria-label="anchor" href="#method-new-"></a></h3> +<p>Create a new mkinds object</p><div class="section"> +<h4 id="usage">Usage<a class="anchor" aria-label="anchor" href="#usage"></a></h4> +<p></p><div class="r"><div class="sourceCode"><pre><code><span class="va"><a href="../reference/mkinds.html">mkinds</a></span><span class="op">$</span><span class="fu">new</span><span class="op">(</span>title <span class="op">=</span> <span class="st">""</span>, <span class="va">data</span>, time_unit <span class="op">=</span> <span class="cn">NA</span>, unit <span class="op">=</span> <span class="cn">NA</span><span class="op">)</span></code></pre></div><p></p></div> +</div> + +<div class="section"> +<h4 id="arguments">Arguments<a class="anchor" aria-label="anchor" href="#arguments"></a></h4> +<p></p><div class="arguments"><dl><dt><code>title</code></dt> +<dd><p>The dataset title</p></dd> -<ul> -<li><p><a href='#method-new'><code>mkinds$new()</code></a></p></li> -<li><p><a href='#method-clone'><code>mkinds$clone()</code></a></p></li> -</ul> -<p><hr> -<a id="method-new"></a></p><h3 class='hasAnchor' id='arguments'><a class='anchor' href='#arguments'></a>Method <code>new()</code></h3> -<p>Create a new mkinds object</p><h4 class='hasAnchor' id='arguments'><a class='anchor' href='#arguments'></a>Usage</h4> -<p><div class="r"></p><pre><span class='va'>mkinds</span><span class='op'>$</span><span class='fu'>new</span><span class='op'>(</span>title <span class='op'>=</span> <span class='st'>""</span>, <span class='va'>data</span>, time_unit <span class='op'>=</span> <span class='cn'>NA</span>, unit <span class='op'>=</span> <span class='cn'>NA</span><span class='op'>)</span></pre><p></div></p> -<h4 class='hasAnchor' id='arguments'><a class='anchor' href='#arguments'></a>Arguments</h4> -<p><div class="arguments"></p><dl> -<dt><code>title</code></dt><dd><p>The dataset title</p></dd> +<dt><code>data</code></dt> +<dd><p>The data</p></dd> -<dt><code>data</code></dt><dd><p>The data</p></dd> -<dt><code>time_unit</code></dt><dd><p>The time unit</p></dd> +<dt><code>time_unit</code></dt> +<dd><p>The time unit</p></dd> -<dt><code>unit</code></dt><dd><p>The unit of the observations</p></dd> -</dl><p></div></p> -<p><hr> -<a id="method-clone"></a></p><h3 class='hasAnchor' id='arguments'><a class='anchor' href='#arguments'></a>Method <code>clone()</code></h3> -<p>The objects of this class are cloneable with this method.</p><h4 class='hasAnchor' id='arguments'><a class='anchor' href='#arguments'></a>Usage</h4> -<p><div class="r"></p><pre><span class='va'>mkinds</span><span class='op'>$</span><span class='fu'>clone</span><span class='op'>(</span>deep <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span></pre><p></div></p> +<dt><code>unit</code></dt> +<dd><p>The unit of the observations</p></dd> -<h4 class='hasAnchor' id='arguments'><a class='anchor' href='#arguments'></a>Arguments</h4> -<p><div class="arguments"></p><dl> -<dt><code>deep</code></dt><dd><p>Whether to make a deep clone.</p></dd> -</dl><p></div></p> +</dl><p></p></div> +</div> + +</div><p></p><hr><a id="method-clone"></a><div class="section"> +<h3 id="method-clone-">Method <code>clone()</code><a class="anchor" aria-label="anchor" href="#method-clone-"></a></h3> +<p>The objects of this class are cloneable with this method.</p><div class="section"> +<h4 id="usage-1">Usage<a class="anchor" aria-label="anchor" href="#usage-1"></a></h4> +<p></p><div class="r"><div class="sourceCode"><pre><code><span class="va">mkinds</span><span class="op">$</span><span class="fu">clone</span><span class="op">(</span>deep <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span></code></pre></div><p></p></div> +</div> + +<div class="section"> +<h4 id="arguments-1">Arguments<a class="anchor" aria-label="anchor" href="#arguments-1"></a></h4> +<p></p><div class="arguments"><dl><dt><code>deep</code></dt> +<dd><p>Whether to make a deep clone.</p></dd> + + +</dl><p></p></div> +</div> +</div> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='va'>mds</span> <span class='op'><-</span> <span class='va'>mkinds</span><span class='op'>$</span><span class='fu'>new</span><span class='op'>(</span><span class='st'>"FOCUS A"</span>, <span class='va'>FOCUS_2006_A</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>mds</span><span class='op'>)</span> -</div><div class='output co'>#> <mkinds> with $title: FOCUS A -#> Observed compounds $observed: parent -#> Sampling times $sampling_times: -#> 0, 3, 7, 14, 30, 62, 90, 118 -#> With a maximum of 1 replicates</div><div class='input'> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="va">mds</span> <span class="op"><-</span> <span class="va">mkinds</span><span class="op">$</span><span class="fu">new</span><span class="op">(</span><span class="st">"FOCUS A"</span>, <span class="va">FOCUS_2006_A</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">mds</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> <mkinds> with $title: FOCUS A </span> +<span class="r-out co"><span class="r-pr">#></span> Observed compounds $observed: parent </span> +<span class="r-out co"><span class="r-pr">#></span> Sampling times $sampling_times:</span> +<span class="r-out co"><span class="r-pr">#></span> 0, 3, 7, 14, 30, 62, 90, 118 </span> +<span class="r-out co"><span class="r-pr">#></span> With a maximum of 1 replicates</span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/mkindsg.html b/docs/reference/mkindsg.html index a9686e4c..bae7488f 100644 --- a/docs/reference/mkindsg.html +++ b/docs/reference/mkindsg.html @@ -1,70 +1,15 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>A class for dataset groups for mkin — mkindsg • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="A class for dataset groups for mkin — mkindsg" /> -<meta property="og:description" content="A container for working with datasets that share at least one compound, +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>A class for dataset groups for mkin — mkindsg • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="A class for dataset groups for mkin — mkindsg"><meta property="og:description" content="A container for working with datasets that share at least one compound, so that combined evaluations are desirable. Time normalisation factors are initialised with a value of 1 for each -dataset if no data are supplied." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +dataset if no data are supplied."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -75,13 +20,12 @@ dataset if no data are supplied." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -90,8 +34,7 @@ dataset if no data are supplied." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -101,6 +44,9 @@ dataset if no data are supplied." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -115,34 +61,27 @@ dataset if no data are supplied." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>A class for dataset groups for mkin</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/mkinds.R'><code>R/mkinds.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/mkinds.R" class="external-link"><code>R/mkinds.R</code></a></small> <div class="hidden name"><code>mkindsg.Rd</code></div> </div> @@ -153,308 +92,329 @@ so that combined evaluations are desirable.</p> dataset if no data are supplied.</p> </div> - <pre class="usage"><span class='co'># S3 method for mkindsg</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>x</span>, data <span class='op'>=</span> <span class='cn'>FALSE</span>, verbose <span class='op'>=</span> <span class='va'>data</span>, <span class='va'>...</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>x</th> - <td><p>An mkindsg object.</p></td> - </tr> - <tr> - <th>data</th> - <td><p>Should the mkinds objects be printed with their data?</p></td> - </tr> - <tr> - <th>verbose</th> - <td><p>Should the mkinds objects be printed?</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Not used.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="public-fields"><a class="anchor" href="#public-fields"></a>Public fields</h2> - - <p><div class="r6-fields"></p><dl> -<dt><code>title</code></dt><dd><p>A title for the dataset group</p></dd> - -<dt><code>ds</code></dt><dd><p>A list of mkinds objects</p></dd> - -<dt><code>observed_n</code></dt><dd><p>Occurrence counts of compounds in datasets</p></dd> - -<dt><code>f_time_norm</code></dt><dd><p>Time normalisation factors</p></dd> - -<dt><code>meta</code></dt><dd><p>A data frame with a row for each dataset, + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for mkindsg</span> +<span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">x</span>, data <span class="op">=</span> <span class="cn">FALSE</span>, verbose <span class="op">=</span> <span class="va">data</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>x</dt> +<dd><p>An mkindsg object.</p></dd> +<dt>data</dt> +<dd><p>Should the mkinds objects be printed with their data?</p></dd> +<dt>verbose</dt> +<dd><p>Should the mkinds objects be printed?</p></dd> +<dt>...</dt> +<dd><p>Not used.</p></dd> +</dl></div> + <div id="public-fields"> + <h2>Public fields</h2> + <p></p><div class="r6-fields"><dl><dt><code>title</code></dt> +<dd><p>A title for the dataset group</p></dd> + + +<dt><code>ds</code></dt> +<dd><p>A list of mkinds objects</p></dd> + + +<dt><code>observed_n</code></dt> +<dd><p>Occurrence counts of compounds in datasets</p></dd> + + +<dt><code>f_time_norm</code></dt> +<dd><p>Time normalisation factors</p></dd> + + +<dt><code>meta</code></dt> +<dd><p>A data frame with a row for each dataset, containing additional information in the form of categorical data (factors) or numerical data (e.g. temperature, moisture, or covariates like soil pH).</p></dd> -</dl><p></div></p> - <h2 class="hasAnchor" id="methods"><a class="anchor" href="#methods"></a>Methods</h2> +</dl><p></p></div> + </div> + <div id="methods"> + <h2>Methods</h2> -<h3 class='hasAnchor' id='arguments'><a class='anchor' href='#arguments'></a>Public methods</h3> - -<ul> -<li><p><a href='#method-new'><code>mkindsg$new()</code></a></p></li> -<li><p><a href='#method-clone'><code>mkindsg$clone()</code></a></p></li> -</ul> -<p><hr> -<a id="method-new"></a></p><h3 class='hasAnchor' id='arguments'><a class='anchor' href='#arguments'></a>Method <code>new()</code></h3> -<p>Create a new mkindsg object</p><h4 class='hasAnchor' id='arguments'><a class='anchor' href='#arguments'></a>Usage</h4> -<p><div class="r"></p><pre><span class='va'>mkindsg</span><span class='op'>$</span><span class='fu'>new</span><span class='op'>(</span>title <span class='op'>=</span> <span class='st'>""</span>, <span class='va'>ds</span>, f_time_norm <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/rep.html'>rep</a></span><span class='op'>(</span><span class='fl'>1</span>, <span class='fu'><a href='https://rdrr.io/r/base/length.html'>length</a></span><span class='op'>(</span><span class='va'>ds</span><span class='op'>)</span><span class='op'>)</span>, <span class='va'>meta</span><span class='op'>)</span></pre><p></div></p> - -<h4 class='hasAnchor' id='arguments'><a class='anchor' href='#arguments'></a>Arguments</h4> -<p><div class="arguments"></p><dl> -<dt><code>title</code></dt><dd><p>The title</p></dd> - -<dt><code>ds</code></dt><dd><p>A list of mkinds objects</p></dd> - -<dt><code>f_time_norm</code></dt><dd><p>Time normalisation factors</p></dd> - -<dt><code>meta</code></dt><dd><p>The meta data</p></dd> - -</dl><p></div></p> -<p><hr> -<a id="method-clone"></a></p><h3 class='hasAnchor' id='arguments'><a class='anchor' href='#arguments'></a>Method <code>clone()</code></h3> -<p>The objects of this class are cloneable with this method.</p><h4 class='hasAnchor' id='arguments'><a class='anchor' href='#arguments'></a>Usage</h4> -<p><div class="r"></p><pre><span class='va'>mkindsg</span><span class='op'>$</span><span class='fu'>clone</span><span class='op'>(</span>deep <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span></pre><p></div></p> - -<h4 class='hasAnchor' id='arguments'><a class='anchor' href='#arguments'></a>Arguments</h4> -<p><div class="arguments"></p><dl> -<dt><code>deep</code></dt><dd><p>Whether to make a deep clone.</p></dd> - -</dl><p></div></p> - - - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='va'>mdsg</span> <span class='op'><-</span> <span class='va'>mkindsg</span><span class='op'>$</span><span class='fu'>new</span><span class='op'>(</span><span class='st'>"Experimental X"</span>, <span class='va'>experimental_data_for_UBA_2019</span><span class='op'>[</span><span class='fl'>6</span><span class='op'>:</span><span class='fl'>10</span><span class='op'>]</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>mdsg</span><span class='op'>)</span> -</div><div class='output co'>#> <mkindsg> holding 5 mkinds objects -#> Title $title: Experimental X -#> Occurrence of observed compounds $observed_n: -#> parent A1 -#> 5 5 </div><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>mdsg</span>, verbose <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> <mkindsg> holding 5 mkinds objects -#> Title $title: Experimental X -#> Occurrence of observed compounds $observed_n: -#> parent A1 -#> 5 5 -#> -#> Datasets $ds: -#> <mkinds> with $title: Soil 6 -#> Observed compounds $observed: parent, A1 -#> Sampling times $sampling_times: -#> 0, 3, 6, 10, 20, 34, 55, 90, 112, 132 -#> With a maximum of 2 replicates -#> Time unit: days -#> Observation unit: \%AR -#> -#> <mkinds> with $title: Soil 7 -#> Observed compounds $observed: parent, A1 -#> Sampling times $sampling_times: -#> 0, 3, 7, 14, 30, 60, 90, 120, 180 -#> With a maximum of 2 replicates -#> Time unit: days -#> Observation unit: \%AR -#> -#> <mkinds> with $title: Soil 8 -#> Observed compounds $observed: parent, A1 -#> Sampling times $sampling_times: -#> 0, 1, 3, 8, 14, 27, 48, 70 -#> With a maximum of 2 replicates -#> Time unit: days -#> Observation unit: \%AR -#> -#> <mkinds> with $title: Soil 9 -#> Observed compounds $observed: parent, A1 -#> Sampling times $sampling_times: -#> 0, 1, 3, 8, 14, 27, 48, 70, 91, 120 -#> With a maximum of 2 replicates -#> Time unit: days -#> Observation unit: \%AR -#> -#> <mkinds> with $title: Soil 10 -#> Observed compounds $observed: parent, A1 -#> Sampling times $sampling_times: -#> 0, 8, 14, 21, 41, 63, 91, 120 -#> With a maximum of 2 replicates -#> Time unit: days -#> Observation unit: \%AR </div><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>mdsg</span>, verbose <span class='op'>=</span> <span class='cn'>TRUE</span>, data <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> <mkindsg> holding 5 mkinds objects -#> Title $title: Experimental X -#> Occurrence of observed compounds $observed_n: -#> parent A1 -#> 5 5 -#> -#> Datasets $ds: -#> <mkinds> with $title: Soil 6 -#> Observed compounds $observed: parent, A1 -#> Sampling times $sampling_times: -#> 0, 3, 6, 10, 20, 34, 55, 90, 112, 132 -#> With a maximum of 2 replicates -#> Time unit: days -#> Observation unit: \%AR -#> time parent A1 -#> 1 0 97.2 NA -#> 2 0 96.4 NA -#> 3 3 71.1 4.3 -#> 4 3 69.2 4.6 -#> 5 6 58.1 7.0 -#> 6 6 56.6 7.2 -#> 7 10 44.4 8.2 -#> 8 10 43.4 8.0 -#> 9 20 33.3 11.0 -#> 10 20 29.2 13.7 -#> 11 34 17.6 11.5 -#> 12 34 18.0 12.7 -#> 13 55 10.5 14.9 -#> 14 55 9.3 14.5 -#> 15 90 4.5 12.1 -#> 16 90 4.7 12.3 -#> 17 112 3.0 9.9 -#> 18 112 3.4 10.2 -#> 19 132 2.3 8.8 -#> 20 132 2.7 7.8 -#> -#> <mkinds> with $title: Soil 7 -#> Observed compounds $observed: parent, A1 -#> Sampling times $sampling_times: -#> 0, 3, 7, 14, 30, 60, 90, 120, 180 -#> With a maximum of 2 replicates -#> Time unit: days -#> Observation unit: \%AR -#> time parent A1 -#> 1 0 93.6 NA -#> 2 0 92.3 NA -#> 3 3 87.0 3.9 -#> 4 3 82.2 3.1 -#> 5 7 74.0 6.9 -#> 6 7 73.9 6.6 -#> 7 14 64.2 10.4 -#> 8 14 69.5 8.3 -#> 9 30 54.0 14.4 -#> 10 30 54.6 13.7 -#> 11 60 41.1 22.1 -#> 12 60 38.4 22.3 -#> 13 90 32.5 27.5 -#> 14 90 35.5 25.4 -#> 15 120 28.1 28.0 -#> 16 120 29.0 26.6 -#> 17 180 26.5 25.8 -#> 18 180 27.6 25.3 -#> -#> <mkinds> with $title: Soil 8 -#> Observed compounds $observed: parent, A1 -#> Sampling times $sampling_times: -#> 0, 1, 3, 8, 14, 27, 48, 70 -#> With a maximum of 2 replicates -#> Time unit: days -#> Observation unit: \%AR -#> time parent A1 -#> 1 0 91.9 NA -#> 2 0 90.8 NA -#> 3 1 64.9 9.6 -#> 4 1 66.2 7.7 -#> 5 3 43.5 15.0 -#> 6 3 44.1 15.1 -#> 7 8 18.3 21.2 -#> 8 8 18.1 21.1 -#> 9 14 10.2 19.7 -#> 10 14 10.8 18.9 -#> 11 27 4.9 17.5 -#> 12 27 3.3 15.9 -#> 13 48 1.6 9.5 -#> 14 48 1.5 9.8 -#> 15 70 1.1 6.2 -#> 16 70 0.9 6.1 -#> -#> <mkinds> with $title: Soil 9 -#> Observed compounds $observed: parent, A1 -#> Sampling times $sampling_times: -#> 0, 1, 3, 8, 14, 27, 48, 70, 91, 120 -#> With a maximum of 2 replicates -#> Time unit: days -#> Observation unit: \%AR -#> time parent A1 -#> 1 0 99.8 NA -#> 2 0 98.3 NA -#> 3 1 77.1 4.2 -#> 4 1 77.2 3.9 -#> 5 3 59.0 7.4 -#> 6 3 58.1 7.9 -#> 7 8 27.4 14.5 -#> 8 8 29.2 13.7 -#> 9 14 19.1 14.2 -#> 10 14 29.6 12.2 -#> 11 27 10.1 13.7 -#> 12 27 18.2 13.2 -#> 13 48 4.5 13.6 -#> 14 48 9.1 15.4 -#> 15 70 2.3 10.4 -#> 16 70 2.9 11.6 -#> 17 91 2.0 10.0 -#> 18 91 1.8 9.5 -#> 19 120 2.0 9.1 -#> 20 120 2.2 9.0 -#> -#> <mkinds> with $title: Soil 10 -#> Observed compounds $observed: parent, A1 -#> Sampling times $sampling_times: -#> 0, 8, 14, 21, 41, 63, 91, 120 -#> With a maximum of 2 replicates -#> Time unit: days -#> Observation unit: \%AR -#> time parent A1 -#> 1 0 96.1 NA -#> 2 0 94.3 NA -#> 3 8 73.9 3.3 -#> 4 8 73.9 3.4 -#> 5 14 69.4 3.9 -#> 6 14 73.1 2.9 -#> 7 21 65.6 6.4 -#> 8 21 65.3 7.2 -#> 9 41 55.9 9.1 -#> 10 41 54.4 8.5 -#> 11 63 47.0 11.7 -#> 12 63 49.3 12.0 -#> 13 91 44.7 13.3 -#> 14 91 46.7 13.2 -#> 15 120 42.1 14.3 -#> 16 120 41.3 12.1</div><div class='input'> -</div></pre> +<div class="section"> +<h3 id="public-methods">Public methods<a class="anchor" aria-label="anchor" href="#public-methods"></a></h3> + +<ul><li><p><a href="#method-new"><code>mkindsg$new()</code></a></p></li> +<li><p><a href="#method-clone"><code>mkindsg$clone()</code></a></p></li> +</ul></div><p></p><hr><a id="method-new"></a><div class="section"> +<h3 id="method-new-">Method <code>new()</code><a class="anchor" aria-label="anchor" href="#method-new-"></a></h3> +<p>Create a new mkindsg object</p><div class="section"> +<h4 id="usage">Usage<a class="anchor" aria-label="anchor" href="#usage"></a></h4> +<p></p><div class="r"><div class="sourceCode"><pre><code><span class="va"><a href="../reference/mkindsg.html">mkindsg</a></span><span class="op">$</span><span class="fu">new</span><span class="op">(</span>title <span class="op">=</span> <span class="st">""</span>, <span class="va">ds</span>, f_time_norm <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/rep.html" class="external-link">rep</a></span><span class="op">(</span><span class="fl">1</span>, <span class="fu"><a href="https://rdrr.io/r/base/length.html" class="external-link">length</a></span><span class="op">(</span><span class="va">ds</span><span class="op">)</span><span class="op">)</span>, <span class="va">meta</span><span class="op">)</span></code></pre></div><p></p></div> +</div> + +<div class="section"> +<h4 id="arguments">Arguments<a class="anchor" aria-label="anchor" href="#arguments"></a></h4> +<p></p><div class="arguments"><dl><dt><code>title</code></dt> +<dd><p>The title</p></dd> + + +<dt><code>ds</code></dt> +<dd><p>A list of mkinds objects</p></dd> + + +<dt><code>f_time_norm</code></dt> +<dd><p>Time normalisation factors</p></dd> + + +<dt><code>meta</code></dt> +<dd><p>The meta data</p></dd> + + +</dl><p></p></div> +</div> + +</div><p></p><hr><a id="method-clone"></a><div class="section"> +<h3 id="method-clone-">Method <code>clone()</code><a class="anchor" aria-label="anchor" href="#method-clone-"></a></h3> +<p>The objects of this class are cloneable with this method.</p><div class="section"> +<h4 id="usage-1">Usage<a class="anchor" aria-label="anchor" href="#usage-1"></a></h4> +<p></p><div class="r"><div class="sourceCode"><pre><code><span class="va">mkindsg</span><span class="op">$</span><span class="fu">clone</span><span class="op">(</span>deep <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span></code></pre></div><p></p></div> +</div> + +<div class="section"> +<h4 id="arguments-1">Arguments<a class="anchor" aria-label="anchor" href="#arguments-1"></a></h4> +<p></p><div class="arguments"><dl><dt><code>deep</code></dt> +<dd><p>Whether to make a deep clone.</p></dd> + + +</dl><p></p></div> +</div> + +</div> + + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="va">mdsg</span> <span class="op"><-</span> <span class="va">mkindsg</span><span class="op">$</span><span class="fu">new</span><span class="op">(</span><span class="st">"Experimental X"</span>, <span class="va">experimental_data_for_UBA_2019</span><span class="op">[</span><span class="fl">6</span><span class="op">:</span><span class="fl">10</span><span class="op">]</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">mdsg</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> <mkindsg> holding 5 mkinds objects</span> +<span class="r-out co"><span class="r-pr">#></span> Title $title: Experimental X </span> +<span class="r-out co"><span class="r-pr">#></span> Occurrence of observed compounds $observed_n:</span> +<span class="r-out co"><span class="r-pr">#></span> parent A1 </span> +<span class="r-out co"><span class="r-pr">#></span> 5 5 </span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">mdsg</span>, verbose <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> <mkindsg> holding 5 mkinds objects</span> +<span class="r-out co"><span class="r-pr">#></span> Title $title: Experimental X </span> +<span class="r-out co"><span class="r-pr">#></span> Occurrence of observed compounds $observed_n:</span> +<span class="r-out co"><span class="r-pr">#></span> parent A1 </span> +<span class="r-out co"><span class="r-pr">#></span> 5 5 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Datasets $ds:</span> +<span class="r-out co"><span class="r-pr">#></span> <mkinds> with $title: Soil 6 </span> +<span class="r-out co"><span class="r-pr">#></span> Observed compounds $observed: parent, A1 </span> +<span class="r-out co"><span class="r-pr">#></span> Sampling times $sampling_times:</span> +<span class="r-out co"><span class="r-pr">#></span> 0, 3, 6, 10, 20, 34, 55, 90, 112, 132 </span> +<span class="r-out co"><span class="r-pr">#></span> With a maximum of 2 replicates</span> +<span class="r-out co"><span class="r-pr">#></span> Time unit: days </span> +<span class="r-out co"><span class="r-pr">#></span> Observation unit: \%AR </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> <mkinds> with $title: Soil 7 </span> +<span class="r-out co"><span class="r-pr">#></span> Observed compounds $observed: parent, A1 </span> +<span class="r-out co"><span class="r-pr">#></span> Sampling times $sampling_times:</span> +<span class="r-out co"><span class="r-pr">#></span> 0, 3, 7, 14, 30, 60, 90, 120, 180 </span> +<span class="r-out co"><span class="r-pr">#></span> With a maximum of 2 replicates</span> +<span class="r-out co"><span class="r-pr">#></span> Time unit: days </span> +<span class="r-out co"><span class="r-pr">#></span> Observation unit: \%AR </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> <mkinds> with $title: Soil 8 </span> +<span class="r-out co"><span class="r-pr">#></span> Observed compounds $observed: parent, A1 </span> +<span class="r-out co"><span class="r-pr">#></span> Sampling times $sampling_times:</span> +<span class="r-out co"><span class="r-pr">#></span> 0, 1, 3, 8, 14, 27, 48, 70 </span> +<span class="r-out co"><span class="r-pr">#></span> With a maximum of 2 replicates</span> +<span class="r-out co"><span class="r-pr">#></span> Time unit: days </span> +<span class="r-out co"><span class="r-pr">#></span> Observation unit: \%AR </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> <mkinds> with $title: Soil 9 </span> +<span class="r-out co"><span class="r-pr">#></span> Observed compounds $observed: parent, A1 </span> +<span class="r-out co"><span class="r-pr">#></span> Sampling times $sampling_times:</span> +<span class="r-out co"><span class="r-pr">#></span> 0, 1, 3, 8, 14, 27, 48, 70, 91, 120 </span> +<span class="r-out co"><span class="r-pr">#></span> With a maximum of 2 replicates</span> +<span class="r-out co"><span class="r-pr">#></span> Time unit: days </span> +<span class="r-out co"><span class="r-pr">#></span> Observation unit: \%AR </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> <mkinds> with $title: Soil 10 </span> +<span class="r-out co"><span class="r-pr">#></span> Observed compounds $observed: parent, A1 </span> +<span class="r-out co"><span class="r-pr">#></span> Sampling times $sampling_times:</span> +<span class="r-out co"><span class="r-pr">#></span> 0, 8, 14, 21, 41, 63, 91, 120 </span> +<span class="r-out co"><span class="r-pr">#></span> With a maximum of 2 replicates</span> +<span class="r-out co"><span class="r-pr">#></span> Time unit: days </span> +<span class="r-out co"><span class="r-pr">#></span> Observation unit: \%AR </span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">mdsg</span>, verbose <span class="op">=</span> <span class="cn">TRUE</span>, data <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> <mkindsg> holding 5 mkinds objects</span> +<span class="r-out co"><span class="r-pr">#></span> Title $title: Experimental X </span> +<span class="r-out co"><span class="r-pr">#></span> Occurrence of observed compounds $observed_n:</span> +<span class="r-out co"><span class="r-pr">#></span> parent A1 </span> +<span class="r-out co"><span class="r-pr">#></span> 5 5 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Datasets $ds:</span> +<span class="r-out co"><span class="r-pr">#></span> <mkinds> with $title: Soil 6 </span> +<span class="r-out co"><span class="r-pr">#></span> Observed compounds $observed: parent, A1 </span> +<span class="r-out co"><span class="r-pr">#></span> Sampling times $sampling_times:</span> +<span class="r-out co"><span class="r-pr">#></span> 0, 3, 6, 10, 20, 34, 55, 90, 112, 132 </span> +<span class="r-out co"><span class="r-pr">#></span> With a maximum of 2 replicates</span> +<span class="r-out co"><span class="r-pr">#></span> Time unit: days </span> +<span class="r-out co"><span class="r-pr">#></span> Observation unit: \%AR </span> +<span class="r-out co"><span class="r-pr">#></span> time parent A1</span> +<span class="r-out co"><span class="r-pr">#></span> 1 0 97.2 NA</span> +<span class="r-out co"><span class="r-pr">#></span> 2 0 96.4 NA</span> +<span class="r-out co"><span class="r-pr">#></span> 3 3 71.1 4.3</span> +<span class="r-out co"><span class="r-pr">#></span> 4 3 69.2 4.6</span> +<span class="r-out co"><span class="r-pr">#></span> 5 6 58.1 7.0</span> +<span class="r-out co"><span class="r-pr">#></span> 6 6 56.6 7.2</span> +<span class="r-out co"><span class="r-pr">#></span> 7 10 44.4 8.2</span> +<span class="r-out co"><span class="r-pr">#></span> 8 10 43.4 8.0</span> +<span class="r-out co"><span class="r-pr">#></span> 9 20 33.3 11.0</span> +<span class="r-out co"><span class="r-pr">#></span> 10 20 29.2 13.7</span> +<span class="r-out co"><span class="r-pr">#></span> 11 34 17.6 11.5</span> +<span class="r-out co"><span class="r-pr">#></span> 12 34 18.0 12.7</span> +<span class="r-out co"><span class="r-pr">#></span> 13 55 10.5 14.9</span> +<span class="r-out co"><span class="r-pr">#></span> 14 55 9.3 14.5</span> +<span class="r-out co"><span class="r-pr">#></span> 15 90 4.5 12.1</span> +<span class="r-out co"><span class="r-pr">#></span> 16 90 4.7 12.3</span> +<span class="r-out co"><span class="r-pr">#></span> 17 112 3.0 9.9</span> +<span class="r-out co"><span class="r-pr">#></span> 18 112 3.4 10.2</span> +<span class="r-out co"><span class="r-pr">#></span> 19 132 2.3 8.8</span> +<span class="r-out co"><span class="r-pr">#></span> 20 132 2.7 7.8</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> <mkinds> with $title: Soil 7 </span> +<span class="r-out co"><span class="r-pr">#></span> Observed compounds $observed: parent, A1 </span> +<span class="r-out co"><span class="r-pr">#></span> Sampling times $sampling_times:</span> +<span class="r-out co"><span class="r-pr">#></span> 0, 3, 7, 14, 30, 60, 90, 120, 180 </span> +<span class="r-out co"><span class="r-pr">#></span> With a maximum of 2 replicates</span> +<span class="r-out co"><span class="r-pr">#></span> Time unit: days </span> +<span class="r-out co"><span class="r-pr">#></span> Observation unit: \%AR </span> +<span class="r-out co"><span class="r-pr">#></span> time parent A1</span> +<span class="r-out co"><span class="r-pr">#></span> 1 0 93.6 NA</span> +<span class="r-out co"><span class="r-pr">#></span> 2 0 92.3 NA</span> +<span class="r-out co"><span class="r-pr">#></span> 3 3 87.0 3.9</span> +<span class="r-out co"><span class="r-pr">#></span> 4 3 82.2 3.1</span> +<span class="r-out co"><span class="r-pr">#></span> 5 7 74.0 6.9</span> +<span class="r-out co"><span class="r-pr">#></span> 6 7 73.9 6.6</span> +<span class="r-out co"><span class="r-pr">#></span> 7 14 64.2 10.4</span> +<span class="r-out co"><span class="r-pr">#></span> 8 14 69.5 8.3</span> +<span class="r-out co"><span class="r-pr">#></span> 9 30 54.0 14.4</span> +<span class="r-out co"><span class="r-pr">#></span> 10 30 54.6 13.7</span> +<span class="r-out co"><span class="r-pr">#></span> 11 60 41.1 22.1</span> +<span class="r-out co"><span class="r-pr">#></span> 12 60 38.4 22.3</span> +<span class="r-out co"><span class="r-pr">#></span> 13 90 32.5 27.5</span> +<span class="r-out co"><span class="r-pr">#></span> 14 90 35.5 25.4</span> +<span class="r-out co"><span class="r-pr">#></span> 15 120 28.1 28.0</span> +<span class="r-out co"><span class="r-pr">#></span> 16 120 29.0 26.6</span> +<span class="r-out co"><span class="r-pr">#></span> 17 180 26.5 25.8</span> +<span class="r-out co"><span class="r-pr">#></span> 18 180 27.6 25.3</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> <mkinds> with $title: Soil 8 </span> +<span class="r-out co"><span class="r-pr">#></span> Observed compounds $observed: parent, A1 </span> +<span class="r-out co"><span class="r-pr">#></span> Sampling times $sampling_times:</span> +<span class="r-out co"><span class="r-pr">#></span> 0, 1, 3, 8, 14, 27, 48, 70 </span> +<span class="r-out co"><span class="r-pr">#></span> With a maximum of 2 replicates</span> +<span class="r-out co"><span class="r-pr">#></span> Time unit: days </span> +<span class="r-out co"><span class="r-pr">#></span> Observation unit: \%AR </span> +<span class="r-out co"><span class="r-pr">#></span> time parent A1</span> +<span class="r-out co"><span class="r-pr">#></span> 1 0 91.9 NA</span> +<span class="r-out co"><span class="r-pr">#></span> 2 0 90.8 NA</span> +<span class="r-out co"><span class="r-pr">#></span> 3 1 64.9 9.6</span> +<span class="r-out co"><span class="r-pr">#></span> 4 1 66.2 7.7</span> +<span class="r-out co"><span class="r-pr">#></span> 5 3 43.5 15.0</span> +<span class="r-out co"><span class="r-pr">#></span> 6 3 44.1 15.1</span> +<span class="r-out co"><span class="r-pr">#></span> 7 8 18.3 21.2</span> +<span class="r-out co"><span class="r-pr">#></span> 8 8 18.1 21.1</span> +<span class="r-out co"><span class="r-pr">#></span> 9 14 10.2 19.7</span> +<span class="r-out co"><span class="r-pr">#></span> 10 14 10.8 18.9</span> +<span class="r-out co"><span class="r-pr">#></span> 11 27 4.9 17.5</span> +<span class="r-out co"><span class="r-pr">#></span> 12 27 3.3 15.9</span> +<span class="r-out co"><span class="r-pr">#></span> 13 48 1.6 9.5</span> +<span class="r-out co"><span class="r-pr">#></span> 14 48 1.5 9.8</span> +<span class="r-out co"><span class="r-pr">#></span> 15 70 1.1 6.2</span> +<span class="r-out co"><span class="r-pr">#></span> 16 70 0.9 6.1</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> <mkinds> with $title: Soil 9 </span> +<span class="r-out co"><span class="r-pr">#></span> Observed compounds $observed: parent, A1 </span> +<span class="r-out co"><span class="r-pr">#></span> Sampling times $sampling_times:</span> +<span class="r-out co"><span class="r-pr">#></span> 0, 1, 3, 8, 14, 27, 48, 70, 91, 120 </span> +<span class="r-out co"><span class="r-pr">#></span> With a maximum of 2 replicates</span> +<span class="r-out co"><span class="r-pr">#></span> Time unit: days </span> +<span class="r-out co"><span class="r-pr">#></span> Observation unit: \%AR </span> +<span class="r-out co"><span class="r-pr">#></span> time parent A1</span> +<span class="r-out co"><span class="r-pr">#></span> 1 0 99.8 NA</span> +<span class="r-out co"><span class="r-pr">#></span> 2 0 98.3 NA</span> +<span class="r-out co"><span class="r-pr">#></span> 3 1 77.1 4.2</span> +<span class="r-out co"><span class="r-pr">#></span> 4 1 77.2 3.9</span> +<span class="r-out co"><span class="r-pr">#></span> 5 3 59.0 7.4</span> +<span class="r-out co"><span class="r-pr">#></span> 6 3 58.1 7.9</span> +<span class="r-out co"><span class="r-pr">#></span> 7 8 27.4 14.5</span> +<span class="r-out co"><span class="r-pr">#></span> 8 8 29.2 13.7</span> +<span class="r-out co"><span class="r-pr">#></span> 9 14 19.1 14.2</span> +<span class="r-out co"><span class="r-pr">#></span> 10 14 29.6 12.2</span> +<span class="r-out co"><span class="r-pr">#></span> 11 27 10.1 13.7</span> +<span class="r-out co"><span class="r-pr">#></span> 12 27 18.2 13.2</span> +<span class="r-out co"><span class="r-pr">#></span> 13 48 4.5 13.6</span> +<span class="r-out co"><span class="r-pr">#></span> 14 48 9.1 15.4</span> +<span class="r-out co"><span class="r-pr">#></span> 15 70 2.3 10.4</span> +<span class="r-out co"><span class="r-pr">#></span> 16 70 2.9 11.6</span> +<span class="r-out co"><span class="r-pr">#></span> 17 91 2.0 10.0</span> +<span class="r-out co"><span class="r-pr">#></span> 18 91 1.8 9.5</span> +<span class="r-out co"><span class="r-pr">#></span> 19 120 2.0 9.1</span> +<span class="r-out co"><span class="r-pr">#></span> 20 120 2.2 9.0</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> <mkinds> with $title: Soil 10 </span> +<span class="r-out co"><span class="r-pr">#></span> Observed compounds $observed: parent, A1 </span> +<span class="r-out co"><span class="r-pr">#></span> Sampling times $sampling_times:</span> +<span class="r-out co"><span class="r-pr">#></span> 0, 8, 14, 21, 41, 63, 91, 120 </span> +<span class="r-out co"><span class="r-pr">#></span> With a maximum of 2 replicates</span> +<span class="r-out co"><span class="r-pr">#></span> Time unit: days </span> +<span class="r-out co"><span class="r-pr">#></span> Observation unit: \%AR </span> +<span class="r-out co"><span class="r-pr">#></span> time parent A1</span> +<span class="r-out co"><span class="r-pr">#></span> 1 0 96.1 NA</span> +<span class="r-out co"><span class="r-pr">#></span> 2 0 94.3 NA</span> +<span class="r-out co"><span class="r-pr">#></span> 3 8 73.9 3.3</span> +<span class="r-out co"><span class="r-pr">#></span> 4 8 73.9 3.4</span> +<span class="r-out co"><span class="r-pr">#></span> 5 14 69.4 3.9</span> +<span class="r-out co"><span class="r-pr">#></span> 6 14 73.1 2.9</span> +<span class="r-out co"><span class="r-pr">#></span> 7 21 65.6 6.4</span> +<span class="r-out co"><span class="r-pr">#></span> 8 21 65.3 7.2</span> +<span class="r-out co"><span class="r-pr">#></span> 9 41 55.9 9.1</span> +<span class="r-out co"><span class="r-pr">#></span> 10 41 54.4 8.5</span> +<span class="r-out co"><span class="r-pr">#></span> 11 63 47.0 11.7</span> +<span class="r-out co"><span class="r-pr">#></span> 12 63 49.3 12.0</span> +<span class="r-out co"><span class="r-pr">#></span> 13 91 44.7 13.3</span> +<span class="r-out co"><span class="r-pr">#></span> 14 91 46.7 13.2</span> +<span class="r-out co"><span class="r-pr">#></span> 15 120 42.1 14.3</span> +<span class="r-out co"><span class="r-pr">#></span> 16 120 41.3 12.1</span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/mkinerrmin.html b/docs/reference/mkinerrmin.html index f22b4350..b72017fe 100644 --- a/docs/reference/mkinerrmin.html +++ b/docs/reference/mkinerrmin.html @@ -1,68 +1,13 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Calculate the minimum error to assume in order to pass the variance test — mkinerrmin • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Calculate the minimum error to assume in order to pass the variance test — mkinerrmin" /> -<meta property="og:description" content="This function finds the smallest relative error still resulting in passing -the chi-squared test as defined in the FOCUS kinetics report from 2006." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Calculate the minimum error to assume in order to pass the variance test — mkinerrmin • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Calculate the minimum error to assume in order to pass the variance test — mkinerrmin"><meta property="og:description" content="This function finds the smallest relative error still resulting in passing +the chi-squared test as defined in the FOCUS kinetics report from 2006."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -73,13 +18,12 @@ the chi-squared test as defined in the FOCUS kinetics report from 2006." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -88,8 +32,7 @@ the chi-squared test as defined in the FOCUS kinetics report from 2006." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -99,6 +42,9 @@ the chi-squared test as defined in the FOCUS kinetics report from 2006." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -113,34 +59,27 @@ the chi-squared test as defined in the FOCUS kinetics report from 2006." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Calculate the minimum error to assume in order to pass the variance test</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/mkinerrmin.R'><code>R/mkinerrmin.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/mkinerrmin.R" class="external-link"><code>R/mkinerrmin.R</code></a></small> <div class="hidden name"><code>mkinerrmin.Rd</code></div> </div> @@ -149,89 +88,94 @@ the chi-squared test as defined in the FOCUS kinetics report from 2006." /> the chi-squared test as defined in the FOCUS kinetics report from 2006.</p> </div> - <pre class="usage"><span class='fu'>mkinerrmin</span><span class='op'>(</span><span class='va'>fit</span>, alpha <span class='op'>=</span> <span class='fl'>0.05</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>fit</th> - <td><p>an object of class <code><a href='mkinfit.html'>mkinfit</a></code>.</p></td> - </tr> - <tr> - <th>alpha</th> - <td><p>The confidence level chosen for the chi-squared test.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">mkinerrmin</span><span class="op">(</span><span class="va">fit</span>, alpha <span class="op">=</span> <span class="fl">0.05</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>fit</dt> +<dd><p>an object of class <code><a href="mkinfit.html">mkinfit</a></code>.</p></dd> +<dt>alpha</dt> +<dd><p>The confidence level chosen for the chi-squared test.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>A dataframe with the following components:</p> -<dt>err.min</dt><dd><p>The -relative error, expressed as a fraction.</p></dd> <dt>n.optim</dt><dd><p>The number of -optimised parameters attributed to the data series.</p></dd> <dt>df</dt><dd><p>The number of +<dl><dt>err.min</dt> +<dd><p>The +relative error, expressed as a fraction.</p></dd> +<dt>n.optim</dt> +<dd><p>The number of +optimised parameters attributed to the data series.</p></dd> +<dt>df</dt> +<dd><p>The number of remaining degrees of freedom for the chi2 error level calculations. Note that mean values are used for the chi2 statistic and therefore every time -point with observed values in the series only counts one time.</p></dd> The +point with observed values in the series only counts one time.</p></dd> +</dl><p>The dataframe has one row for the total dataset and one further row for each -observed state variable in the model. - - <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2> - - <p>This function is used internally by <code><a href='summary.mkinfit.html'>summary.mkinfit</a></code>.</p> - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - - <p>FOCUS (2006) “Guidance Document on Estimating Persistence +observed state variable in the model.</p> + </div> + <div id="details"> + <h2>Details</h2> + <p>This function is used internally by <code><a href="summary.mkinfit.html">summary.mkinfit</a></code>.</p> + </div> + <div id="references"> + <h2>References</h2> + <p>FOCUS (2006) “Guidance Document on Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in EU -Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC +Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC Document Reference Sanco/10058/2005 version 2.0, 434 pp, -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='va'>SFO_SFO</span> <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"m1"</span><span class='op'>)</span>, - m1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, - use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> -<span class='va'>fit_FOCUS_D</span> <span class='op'>=</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_2006_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='warning'>Warning: Observations with value of zero were removed from the data</span></div><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/Round.html'>round</a></span><span class='op'>(</span><span class='fu'>mkinerrmin</span><span class='op'>(</span><span class='va'>fit_FOCUS_D</span><span class='op'>)</span>, <span class='fl'>4</span><span class='op'>)</span> -</div><div class='output co'>#> err.min n.optim df -#> All data 0.0640 4 15 -#> parent 0.0646 2 7 -#> m1 0.0469 2 8</div><div class='input'><span class='co'># \dontrun{</span> - <span class='va'>fit_FOCUS_E</span> <span class='op'>=</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_2006_E</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - <span class='fu'><a href='https://rdrr.io/r/base/Round.html'>round</a></span><span class='op'>(</span><span class='fu'>mkinerrmin</span><span class='op'>(</span><span class='va'>fit_FOCUS_E</span><span class='op'>)</span>, <span class='fl'>4</span><span class='op'>)</span> -</div><div class='output co'>#> err.min n.optim df -#> All data 0.1544 4 13 -#> parent 0.1659 2 7 -#> m1 0.1095 2 6</div><div class='input'><span class='co'># }</span> - -</div></pre> +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="va">SFO_SFO</span> <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"m1"</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">fit_FOCUS_D</span> <span class="op">=</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_2006_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/Round.html" class="external-link">round</a></span><span class="op">(</span><span class="fu">mkinerrmin</span><span class="op">(</span><span class="va">fit_FOCUS_D</span><span class="op">)</span>, <span class="fl">4</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> err.min n.optim df</span> +<span class="r-out co"><span class="r-pr">#></span> All data 0.0640 4 15</span> +<span class="r-out co"><span class="r-pr">#></span> parent 0.0646 2 7</span> +<span class="r-out co"><span class="r-pr">#></span> m1 0.0469 2 8</span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"> <span class="va">fit_FOCUS_E</span> <span class="op">=</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_2006_E</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/Round.html" class="external-link">round</a></span><span class="op">(</span><span class="fu">mkinerrmin</span><span class="op">(</span><span class="va">fit_FOCUS_E</span><span class="op">)</span>, <span class="fl">4</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> err.min n.optim df</span> +<span class="r-out co"><span class="r-pr">#></span> All data 0.1544 4 13</span> +<span class="r-out co"><span class="r-pr">#></span> parent 0.1659 2 7</span> +<span class="r-out co"><span class="r-pr">#></span> m1 0.1095 2 6</span> +<span class="r-in"><span class="co"># }</span></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/mkinerrplot-1.png b/docs/reference/mkinerrplot-1.png Binary files differindex bae6071d..49bb1c0e 100644 --- a/docs/reference/mkinerrplot-1.png +++ b/docs/reference/mkinerrplot-1.png diff --git a/docs/reference/mkinerrplot.html b/docs/reference/mkinerrplot.html index 361ce79a..5dc188fe 100644 --- a/docs/reference/mkinerrplot.html +++ b/docs/reference/mkinerrplot.html @@ -1,71 +1,16 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Function to plot squared residuals and the error model for an mkin object — mkinerrplot • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Function to plot squared residuals and the error model for an mkin object — mkinerrplot" /> -<meta property="og:description" content="This function plots the squared residuals for the specified subset of the +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Function to plot squared residuals and the error model for an mkin object — mkinerrplot • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Function to plot squared residuals and the error model for an mkin object — mkinerrplot"><meta property="og:description" content="This function plots the squared residuals for the specified subset of the observed variables from an mkinfit object. In addition, one or more dashed line(s) show the fitted error model. A combined plot of the fitted model and this error model plot can be obtained with plot.mkinfit -using the argument show_errplot = TRUE." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +using the argument show_errplot = TRUE."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -76,13 +21,12 @@ using the argument show_errplot = TRUE." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -91,8 +35,7 @@ using the argument show_errplot = TRUE." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -102,6 +45,9 @@ using the argument show_errplot = TRUE." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -116,34 +62,27 @@ using the argument show_errplot = TRUE." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Function to plot squared residuals and the error model for an mkin object</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/mkinerrplot.R'><code>R/mkinerrplot.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/mkinerrplot.R" class="external-link"><code>R/mkinerrplot.R</code></a></small> <div class="hidden name"><code>mkinerrplot.Rd</code></div> </div> @@ -151,128 +90,107 @@ using the argument show_errplot = TRUE." /> <p>This function plots the squared residuals for the specified subset of the observed variables from an mkinfit object. In addition, one or more dashed line(s) show the fitted error model. A combined plot of the fitted model -and this error model plot can be obtained with <code><a href='plot.mkinfit.html'>plot.mkinfit</a></code> +and this error model plot can be obtained with <code><a href="plot.mkinfit.html">plot.mkinfit</a></code> using the argument <code>show_errplot = TRUE</code>.</p> </div> - <pre class="usage"><span class='fu'>mkinerrplot</span><span class='op'>(</span> - <span class='va'>object</span>, - obs_vars <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/names.html'>names</a></span><span class='op'>(</span><span class='va'>object</span><span class='op'>$</span><span class='va'>mkinmod</span><span class='op'>$</span><span class='va'>map</span><span class='op'>)</span>, - xlim <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>1.1</span> <span class='op'>*</span> <span class='fu'><a href='https://rdrr.io/r/base/Extremes.html'>max</a></span><span class='op'>(</span><span class='va'>object</span><span class='op'>$</span><span class='va'>data</span><span class='op'>$</span><span class='va'>predicted</span><span class='op'>)</span><span class='op'>)</span>, - xlab <span class='op'>=</span> <span class='st'>"Predicted"</span>, - ylab <span class='op'>=</span> <span class='st'>"Squared residual"</span>, - maxy <span class='op'>=</span> <span class='st'>"auto"</span>, - legend <span class='op'>=</span> <span class='cn'>TRUE</span>, - lpos <span class='op'>=</span> <span class='st'>"topright"</span>, - col_obs <span class='op'>=</span> <span class='st'>"auto"</span>, - pch_obs <span class='op'>=</span> <span class='st'>"auto"</span>, - frame <span class='op'>=</span> <span class='cn'>TRUE</span>, - <span class='va'>...</span> -<span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">mkinerrplot</span><span class="op">(</span> + <span class="va">object</span>, + obs_vars <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">object</span><span class="op">$</span><span class="va">mkinmod</span><span class="op">$</span><span class="va">map</span><span class="op">)</span>, + xlim <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">1.1</span> <span class="op">*</span> <span class="fu"><a href="https://rdrr.io/r/base/Extremes.html" class="external-link">max</a></span><span class="op">(</span><span class="va">object</span><span class="op">$</span><span class="va">data</span><span class="op">$</span><span class="va">predicted</span><span class="op">)</span><span class="op">)</span>, + xlab <span class="op">=</span> <span class="st">"Predicted"</span>, + ylab <span class="op">=</span> <span class="st">"Squared residual"</span>, + maxy <span class="op">=</span> <span class="st">"auto"</span>, + legend <span class="op">=</span> <span class="cn">TRUE</span>, + lpos <span class="op">=</span> <span class="st">"topright"</span>, + col_obs <span class="op">=</span> <span class="st">"auto"</span>, + pch_obs <span class="op">=</span> <span class="st">"auto"</span>, + frame <span class="op">=</span> <span class="cn">TRUE</span>, + <span class="va">...</span> +<span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>A fit represented in an <code><a href='mkinfit.html'>mkinfit</a></code> object.</p></td> - </tr> - <tr> - <th>obs_vars</th> - <td><p>A character vector of names of the observed variables for + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>A fit represented in an <code><a href="mkinfit.html">mkinfit</a></code> object.</p></dd> +<dt>obs_vars</dt> +<dd><p>A character vector of names of the observed variables for which residuals should be plotted. Defaults to all observed variables in -the model</p></td> - </tr> - <tr> - <th>xlim</th> - <td><p>plot range in x direction.</p></td> - </tr> - <tr> - <th>xlab</th> - <td><p>Label for the x axis.</p></td> - </tr> - <tr> - <th>ylab</th> - <td><p>Label for the y axis.</p></td> - </tr> - <tr> - <th>maxy</th> - <td><p>Maximum value of the residuals. This is used for the scaling of -the y axis and defaults to "auto".</p></td> - </tr> - <tr> - <th>legend</th> - <td><p>Should a legend be plotted?</p></td> - </tr> - <tr> - <th>lpos</th> - <td><p>Where should the legend be placed? Default is "topright". Will -be passed on to <code><a href='https://rdrr.io/r/graphics/legend.html'>legend</a></code>.</p></td> - </tr> - <tr> - <th>col_obs</th> - <td><p>Colors for the observed variables.</p></td> - </tr> - <tr> - <th>pch_obs</th> - <td><p>Symbols to be used for the observed variables.</p></td> - </tr> - <tr> - <th>frame</th> - <td><p>Should a frame be drawn around the plots?</p></td> - </tr> - <tr> - <th>...</th> - <td><p>further arguments passed to <code><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></code>.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - +the model</p></dd> +<dt>xlim</dt> +<dd><p>plot range in x direction.</p></dd> +<dt>xlab</dt> +<dd><p>Label for the x axis.</p></dd> +<dt>ylab</dt> +<dd><p>Label for the y axis.</p></dd> +<dt>maxy</dt> +<dd><p>Maximum value of the residuals. This is used for the scaling of +the y axis and defaults to "auto".</p></dd> +<dt>legend</dt> +<dd><p>Should a legend be plotted?</p></dd> +<dt>lpos</dt> +<dd><p>Where should the legend be placed? Default is "topright". Will +be passed on to <code><a href="https://rdrr.io/r/graphics/legend.html" class="external-link">legend</a></code>.</p></dd> +<dt>col_obs</dt> +<dd><p>Colors for the observed variables.</p></dd> +<dt>pch_obs</dt> +<dd><p>Symbols to be used for the observed variables.</p></dd> +<dt>frame</dt> +<dd><p>Should a frame be drawn around the plots?</p></dd> +<dt>...</dt> +<dd><p>further arguments passed to <code><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></code>.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>Nothing is returned by this function, as it is called for its side effect, namely to produce a plot.</p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p><code><a href='mkinplot.html'>mkinplot</a></code>, for a way to plot the data and the fitted + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p><code><a href="mkinplot.html">mkinplot</a></code>, for a way to plot the data and the fitted lines of the mkinfit object.</p></div> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='co'># \dontrun{</span> -<span class='va'>model</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"m1"</span><span class='op'>)</span>, m1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'><span class='va'>fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>model</span>, <span class='va'>FOCUS_2006_D</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='warning'>Warning: Observations with value of zero were removed from the data</span></div><div class='input'><span class='fu'>mkinerrplot</span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span> -</div><div class='img'><img src='mkinerrplot-1.png' alt='' width='700' height='433' /></div><div class='input'><span class='co'># }</span> - -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="va">model</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"m1"</span><span class="op">)</span>, m1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="va">fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">model</span>, <span class="va">FOCUS_2006_D</span>, error_model <span class="op">=</span> <span class="st">"tc"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu">mkinerrplot</span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></span> +<span class="r-plt img"><img src="mkinerrplot-1.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="co"># }</span></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/mkinfit-1.png b/docs/reference/mkinfit-1.png Binary files differindex e1d0f2f4..7c51deb6 100644 --- a/docs/reference/mkinfit-1.png +++ b/docs/reference/mkinfit-1.png diff --git a/docs/reference/mkinfit.html b/docs/reference/mkinfit.html index 2c162e49..a0644947 100644 --- a/docs/reference/mkinfit.html +++ b/docs/reference/mkinfit.html @@ -1,46 +1,5 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Fit a kinetic model to data with one or more state variables — mkinfit • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Fit a kinetic model to data with one or more state variables — mkinfit" /> -<meta property="og:description" content="This function maximises the likelihood of the observed data using the Port +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Fit a kinetic model to data with one or more state variables — mkinfit • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Fit a kinetic model to data with one or more state variables — mkinfit"><meta property="og:description" content="This function maximises the likelihood of the observed data using the Port algorithm stats::nlminb(), and the specified initial or fixed parameters and starting values. In each step of the optimisation, the kinetic model is solved using the function mkinpredict(), except @@ -48,28 +7,14 @@ if an analytical solution is implemented, in which case the model is solved using the degradation function in the mkinmod object. The parameters of the selected error model are fitted simultaneously with the degradation model parameters, as both of them are arguments of the -likelihood function." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +likelihood function."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -80,13 +25,12 @@ likelihood function." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -95,8 +39,7 @@ likelihood function." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -106,6 +49,9 @@ likelihood function." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -120,91 +66,82 @@ likelihood function." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Fit a kinetic model to data with one or more state variables</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/mkinfit.R'><code>R/mkinfit.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/mkinfit.R" class="external-link"><code>R/mkinfit.R</code></a></small> <div class="hidden name"><code>mkinfit.Rd</code></div> </div> <div class="ref-description"> <p>This function maximises the likelihood of the observed data using the Port -algorithm <code><a href='https://rdrr.io/r/stats/nlminb.html'>stats::nlminb()</a></code>, and the specified initial or fixed +algorithm <code><a href="https://rdrr.io/r/stats/nlminb.html" class="external-link">stats::nlminb()</a></code>, and the specified initial or fixed parameters and starting values. In each step of the optimisation, the -kinetic model is solved using the function <code><a href='mkinpredict.html'>mkinpredict()</a></code>, except +kinetic model is solved using the function <code><a href="mkinpredict.html">mkinpredict()</a></code>, except if an analytical solution is implemented, in which case the model is solved -using the degradation function in the <a href='mkinmod.html'>mkinmod</a> object. The +using the degradation function in the <a href="mkinmod.html">mkinmod</a> object. The parameters of the selected error model are fitted simultaneously with the degradation model parameters, as both of them are arguments of the likelihood function.</p> </div> - <pre class="usage"><span class='fu'>mkinfit</span><span class='op'>(</span> - <span class='va'>mkinmod</span>, - <span class='va'>observed</span>, - parms.ini <span class='op'>=</span> <span class='st'>"auto"</span>, - state.ini <span class='op'>=</span> <span class='st'>"auto"</span>, - err.ini <span class='op'>=</span> <span class='st'>"auto"</span>, - fixed_parms <span class='op'>=</span> <span class='cn'>NULL</span>, - fixed_initials <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/names.html'>names</a></span><span class='op'>(</span><span class='va'>mkinmod</span><span class='op'>$</span><span class='va'>diffs</span><span class='op'>)</span><span class='op'>[</span><span class='op'>-</span><span class='fl'>1</span><span class='op'>]</span>, - from_max_mean <span class='op'>=</span> <span class='cn'>FALSE</span>, - solution_type <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"auto"</span>, <span class='st'>"analytical"</span>, <span class='st'>"eigen"</span>, <span class='st'>"deSolve"</span><span class='op'>)</span>, - method.ode <span class='op'>=</span> <span class='st'>"lsoda"</span>, - use_compiled <span class='op'>=</span> <span class='st'>"auto"</span>, - control <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>eval.max <span class='op'>=</span> <span class='fl'>300</span>, iter.max <span class='op'>=</span> <span class='fl'>200</span><span class='op'>)</span>, - transform_rates <span class='op'>=</span> <span class='cn'>TRUE</span>, - transform_fractions <span class='op'>=</span> <span class='cn'>TRUE</span>, - quiet <span class='op'>=</span> <span class='cn'>FALSE</span>, - atol <span class='op'>=</span> <span class='fl'>1e-08</span>, - rtol <span class='op'>=</span> <span class='fl'>1e-10</span>, - error_model <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"const"</span>, <span class='st'>"obs"</span>, <span class='st'>"tc"</span><span class='op'>)</span>, - error_model_algorithm <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"auto"</span>, <span class='st'>"d_3"</span>, <span class='st'>"direct"</span>, <span class='st'>"twostep"</span>, <span class='st'>"threestep"</span>, - <span class='st'>"fourstep"</span>, <span class='st'>"IRLS"</span>, <span class='st'>"OLS"</span><span class='op'>)</span>, - reweight.tol <span class='op'>=</span> <span class='fl'>1e-08</span>, - reweight.max.iter <span class='op'>=</span> <span class='fl'>10</span>, - trace_parms <span class='op'>=</span> <span class='cn'>FALSE</span>, - test_residuals <span class='op'>=</span> <span class='cn'>FALSE</span>, - <span class='va'>...</span> -<span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">mkinfit</span><span class="op">(</span> + <span class="va">mkinmod</span>, + <span class="va">observed</span>, + parms.ini <span class="op">=</span> <span class="st">"auto"</span>, + state.ini <span class="op">=</span> <span class="st">"auto"</span>, + err.ini <span class="op">=</span> <span class="st">"auto"</span>, + fixed_parms <span class="op">=</span> <span class="cn">NULL</span>, + fixed_initials <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">mkinmod</span><span class="op">$</span><span class="va">diffs</span><span class="op">)</span><span class="op">[</span><span class="op">-</span><span class="fl">1</span><span class="op">]</span>, + from_max_mean <span class="op">=</span> <span class="cn">FALSE</span>, + solution_type <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"auto"</span>, <span class="st">"analytical"</span>, <span class="st">"eigen"</span>, <span class="st">"deSolve"</span><span class="op">)</span>, + method.ode <span class="op">=</span> <span class="st">"lsoda"</span>, + use_compiled <span class="op">=</span> <span class="st">"auto"</span>, + control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>eval.max <span class="op">=</span> <span class="fl">300</span>, iter.max <span class="op">=</span> <span class="fl">200</span><span class="op">)</span>, + transform_rates <span class="op">=</span> <span class="cn">TRUE</span>, + transform_fractions <span class="op">=</span> <span class="cn">TRUE</span>, + quiet <span class="op">=</span> <span class="cn">FALSE</span>, + atol <span class="op">=</span> <span class="fl">1e-08</span>, + rtol <span class="op">=</span> <span class="fl">1e-10</span>, + error_model <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"const"</span>, <span class="st">"obs"</span>, <span class="st">"tc"</span><span class="op">)</span>, + error_model_algorithm <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"auto"</span>, <span class="st">"d_3"</span>, <span class="st">"direct"</span>, <span class="st">"twostep"</span>, <span class="st">"threestep"</span>, + <span class="st">"fourstep"</span>, <span class="st">"IRLS"</span>, <span class="st">"OLS"</span><span class="op">)</span>, + reweight.tol <span class="op">=</span> <span class="fl">1e-08</span>, + reweight.max.iter <span class="op">=</span> <span class="fl">10</span>, + trace_parms <span class="op">=</span> <span class="cn">FALSE</span>, + test_residuals <span class="op">=</span> <span class="cn">FALSE</span>, + <span class="va">...</span> +<span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>mkinmod</th> - <td><p>A list of class <a href='mkinmod.html'>mkinmod</a>, containing the kinetic + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>mkinmod</dt> +<dd><p>A list of class <a href="mkinmod.html">mkinmod</a>, containing the kinetic model to be fitted to the data, or one of the shorthand names ("SFO", "FOMC", "DFOP", "HS", "SFORB", "IORE"). If a shorthand name is given, a parent only degradation model is generated for the variable with the -highest value in <code>observed</code>.</p></td> - </tr> - <tr> - <th>observed</th> - <td><p>A dataframe with the observed data. The first column called +highest value in <code>observed</code>.</p></dd> +<dt>observed</dt> +<dd><p>A dataframe with the observed data. The first column called "name" must contain the name of the observed variable for each data point. The second column must contain the times of observation, named "time". The third column must be named "value" and contain the observed values. @@ -212,11 +149,9 @@ Zero values in the "value" column will be removed, with a warning, in order to avoid problems with fitting the two-component error model. This is not expected to be a problem, because in general, values of zero are not observed in degradation data, because there is a lower limit of -detection.</p></td> - </tr> - <tr> - <th>parms.ini</th> - <td><p>A named vector of initial values for the parameters, +detection.</p></dd> +<dt>parms.ini</dt> +<dd><p>A named vector of initial values for the parameters, including parameters to be optimised and potentially also fixed parameters as indicated by <code>fixed_parms</code>. If set to "auto", initial values for rate constants are set to default values. Using parameter names that are @@ -225,113 +160,83 @@ not in the model gives an error.</p> needs. You can use the parameter lists "bparms.ode" from a previously fitted model, which contains the differential equation parameters from this model. This works nicely if the models are nested. An example is -given below.</p></td> - </tr> - <tr> - <th>state.ini</th> - <td><p>A named vector of initial values for the state variables of +given below.</p></dd> +<dt>state.ini</dt> +<dd><p>A named vector of initial values for the state variables of the model. In case the observed variables are represented by more than one model variable, the names will differ from the names of the observed -variables (see <code>map</code> component of <a href='mkinmod.html'>mkinmod</a>). The default +variables (see <code>map</code> component of <a href="mkinmod.html">mkinmod</a>). The default is to set the initial value of the first model variable to the mean of the time zero values for the variable with the maximum observed value, and all others to 0. If this variable has no time zero observations, its initial -value is set to 100.</p></td> - </tr> - <tr> - <th>err.ini</th> - <td><p>A named vector of initial values for the error model +value is set to 100.</p></dd> +<dt>err.ini</dt> +<dd><p>A named vector of initial values for the error model parameters to be optimised. If set to "auto", initial values are set to default values. Otherwise, inital values for all error model parameters -must be given.</p></td> - </tr> - <tr> - <th>fixed_parms</th> - <td><p>The names of parameters that should not be optimised but +must be given.</p></dd> +<dt>fixed_parms</dt> +<dd><p>The names of parameters that should not be optimised but rather kept at the values specified in <code>parms.ini</code>. Alternatively, a named numeric vector of parameters to be fixed, regardless of the values -in parms.ini.</p></td> - </tr> - <tr> - <th>fixed_initials</th> - <td><p>The names of model variables for which the initial +in parms.ini.</p></dd> +<dt>fixed_initials</dt> +<dd><p>The names of model variables for which the initial state at time 0 should be excluded from the optimisation. Defaults to all -state variables except for the first one.</p></td> - </tr> - <tr> - <th>from_max_mean</th> - <td><p>If this is set to TRUE, and the model has only one +state variables except for the first one.</p></dd> +<dt>from_max_mean</dt> +<dd><p>If this is set to TRUE, and the model has only one observed variable, then data before the time of the maximum observed value (after averaging for each sampling time) are discarded, and this time is subtracted from all remaining time values, so the time of the maximum -observed mean value is the new time zero.</p></td> - </tr> - <tr> - <th>solution_type</th> - <td><p>If set to "eigen", the solution of the system of +observed mean value is the new time zero.</p></dd> +<dt>solution_type</dt> +<dd><p>If set to "eigen", the solution of the system of differential equations is based on the spectral decomposition of the coefficient matrix in cases that this is possible. If set to "deSolve", a -numerical <a href='https://rdrr.io/pkg/deSolve/man/ode.html'>ode solver from package deSolve</a> is used. If +numerical <a href="https://rdrr.io/pkg/deSolve/man/ode.html" class="external-link">ode solver from package deSolve</a> is used. If set to "analytical", an analytical solution of the model is used. This is only implemented for relatively simple degradation models. The default is "auto", which uses "analytical" if possible, otherwise "deSolve" if a compiler is present, and "eigen" if no compiler is present and the model -can be expressed using eigenvalues and eigenvectors.</p></td> - </tr> - <tr> - <th>method.ode</th> - <td><p>The solution method passed via <code><a href='mkinpredict.html'>mkinpredict()</a></code> -to <code><a href='https://rdrr.io/pkg/deSolve/man/ode.html'>deSolve::ode()</a></code> in case the solution type is "deSolve". The default -"lsoda" is performant, but sometimes fails to converge.</p></td> - </tr> - <tr> - <th>use_compiled</th> - <td><p>If set to <code>FALSE</code>, no compiled version of the -<a href='mkinmod.html'>mkinmod</a> model is used in the calls to <code><a href='mkinpredict.html'>mkinpredict()</a></code> even if a compiled -version is present.</p></td> - </tr> - <tr> - <th>control</th> - <td><p>A list of control arguments passed to <code><a href='https://rdrr.io/r/stats/nlminb.html'>stats::nlminb()</a></code>.</p></td> - </tr> - <tr> - <th>transform_rates</th> - <td><p>Boolean specifying if kinetic rate constants should +can be expressed using eigenvalues and eigenvectors.</p></dd> +<dt>method.ode</dt> +<dd><p>The solution method passed via <code><a href="mkinpredict.html">mkinpredict()</a></code> +to <code><a href="https://rdrr.io/pkg/deSolve/man/ode.html" class="external-link">deSolve::ode()</a></code> in case the solution type is "deSolve". The default +"lsoda" is performant, but sometimes fails to converge.</p></dd> +<dt>use_compiled</dt> +<dd><p>If set to <code>FALSE</code>, no compiled version of the +<a href="mkinmod.html">mkinmod</a> model is used in the calls to <code><a href="mkinpredict.html">mkinpredict()</a></code> even if a compiled +version is present.</p></dd> +<dt>control</dt> +<dd><p>A list of control arguments passed to <code><a href="https://rdrr.io/r/stats/nlminb.html" class="external-link">stats::nlminb()</a></code>.</p></dd> +<dt>transform_rates</dt> +<dd><p>Boolean specifying if kinetic rate constants should be transformed in the model specification used in the fitting for better compliance with the assumption of normal distribution of the estimator. If TRUE, also alpha and beta parameters of the FOMC model are log-transformed, as well as k1 and k2 rate constants for the DFOP and HS models and the break point tb of the HS model. If FALSE, zero is used as -a lower bound for the rates in the optimisation.</p></td> - </tr> - <tr> - <th>transform_fractions</th> - <td><p>Boolean specifying if formation fractions +a lower bound for the rates in the optimisation.</p></dd> +<dt>transform_fractions</dt> +<dd><p>Boolean specifying if formation fractions should be transformed in the model specification used in the fitting for better compliance with the assumption of normal distribution of the estimator. The default (TRUE) is to do transformations. If TRUE, the g parameter of the DFOP model is also transformed. Transformations -are described in <a href='transform_odeparms.html'>transform_odeparms</a>.</p></td> - </tr> - <tr> - <th>quiet</th> - <td><p>Suppress printing out the current value of the negative -log-likelihood after each improvement?</p></td> - </tr> - <tr> - <th>atol</th> - <td><p>Absolute error tolerance, passed to <code><a href='https://rdrr.io/pkg/deSolve/man/ode.html'>deSolve::ode()</a></code>. Default -is 1e-8, which is lower than the default in the <code><a href='https://rdrr.io/pkg/deSolve/man/lsoda.html'>deSolve::lsoda()</a></code> -function which is used per default.</p></td> - </tr> - <tr> - <th>rtol</th> - <td><p>Absolute error tolerance, passed to <code><a href='https://rdrr.io/pkg/deSolve/man/ode.html'>deSolve::ode()</a></code>. Default -is 1e-10, much lower than in <code><a href='https://rdrr.io/pkg/deSolve/man/lsoda.html'>deSolve::lsoda()</a></code>.</p></td> - </tr> - <tr> - <th>error_model</th> - <td><p>If the error model is "const", a constant standard +are described in <a href="transform_odeparms.html">transform_odeparms</a>.</p></dd> +<dt>quiet</dt> +<dd><p>Suppress printing out the current value of the negative +log-likelihood after each improvement?</p></dd> +<dt>atol</dt> +<dd><p>Absolute error tolerance, passed to <code><a href="https://rdrr.io/pkg/deSolve/man/ode.html" class="external-link">deSolve::ode()</a></code>. Default +is 1e-8, which is lower than the default in the <code><a href="https://rdrr.io/pkg/deSolve/man/lsoda.html" class="external-link">deSolve::lsoda()</a></code> +function which is used per default.</p></dd> +<dt>rtol</dt> +<dd><p>Absolute error tolerance, passed to <code><a href="https://rdrr.io/pkg/deSolve/man/ode.html" class="external-link">deSolve::ode()</a></code>. Default +is 1e-10, much lower than in <code><a href="https://rdrr.io/pkg/deSolve/man/lsoda.html" class="external-link">deSolve::lsoda()</a></code>.</p></dd> +<dt>error_model</dt> +<dd><p>If the error model is "const", a constant standard deviation is assumed.</p> <p>If the error model is "obs", each observed variable is assumed to have its own variance.</p> @@ -340,11 +245,9 @@ error model similar to the one described by Rocke and Lorenzato (1995) is used for setting up the likelihood function. Note that this model deviates from the model by Rocke and Lorenzato, as their model implies that the errors follow a lognormal distribution for large values, not a -normal distribution as assumed by this method.</p></td> - </tr> - <tr> - <th>error_model_algorithm</th> - <td><p>If "auto", the selected algorithm depends on +normal distribution as assumed by this method.</p></dd> +<dt>error_model_algorithm</dt> +<dd><p>If "auto", the selected algorithm depends on the error model. If the error model is "const", unweighted nonlinear least squares fitting ("OLS") is selected. If the error model is "obs", or "tc", the "d_3" algorithm is selected.</p> @@ -367,372 +270,375 @@ degradation and error model parameters.</p> unweighted least squares, and then iterates optimization of the error model parameters and subsequent optimization of the degradation model using those error model parameters, until the error model parameters -converge.</p></td> - </tr> - <tr> - <th>reweight.tol</th> - <td><p>Tolerance for the convergence criterion calculated from -the error model parameters in IRLS fits.</p></td> - </tr> - <tr> - <th>reweight.max.iter</th> - <td><p>Maximum number of iterations in IRLS fits.</p></td> - </tr> - <tr> - <th>trace_parms</th> - <td><p>Should a trace of the parameter values be listed?</p></td> - </tr> - <tr> - <th>test_residuals</th> - <td><p>Should the residuals be tested for normal distribution?</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Further arguments that will be passed on to -<code><a href='https://rdrr.io/pkg/deSolve/man/ode.html'>deSolve::ode()</a></code>.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - +converge.</p></dd> +<dt>reweight.tol</dt> +<dd><p>Tolerance for the convergence criterion calculated from +the error model parameters in IRLS fits.</p></dd> +<dt>reweight.max.iter</dt> +<dd><p>Maximum number of iterations in IRLS fits.</p></dd> +<dt>trace_parms</dt> +<dd><p>Should a trace of the parameter values be listed?</p></dd> +<dt>test_residuals</dt> +<dd><p>Should the residuals be tested for normal distribution?</p></dd> +<dt>...</dt> +<dd><p>Further arguments that will be passed on to +<code><a href="https://rdrr.io/pkg/deSolve/man/ode.html" class="external-link">deSolve::ode()</a></code>.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>A list with "mkinfit" in the class attribute.</p> - <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2> - + </div> + <div id="details"> + <h2>Details</h2> <p>Per default, parameters in the kinetic models are internally transformed in order to better satisfy the assumption of a normal distribution of their estimators.</p> - <h2 class="hasAnchor" id="note"><a class="anchor" href="#note"></a>Note</h2> - + </div> + <div id="note"> + <h2>Note</h2> <p>When using the "IORE" submodel for metabolites, fitting with "transform_rates = TRUE" (the default) often leads to failures of the numerical ODE solver. In this situation it may help to switch off the internal rate transformation.</p> - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - + </div> + <div id="references"> + <h2>References</h2> <p>Rocke DM and Lorenzato S (1995) A two-component model for measurement error in analytical chemistry. <em>Technometrics</em> 37(2), 176-184.</p> <p>Ranke J and Meinecke S (2019) Error Models for the Kinetic Evaluation of Chemical Degradation Data. <em>Environments</em> 6(12) 124 -doi: <a href='https://doi.org/10.3390/environments6120124'>10.3390/environments6120124</a> +doi: <a href="https://doi.org/10.3390/environments6120124" class="external-link">10.3390/environments6120124</a> .</p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p><a href='summary.mkinfit.html'>summary.mkinfit</a>, <a href='plot.mkinfit.html'>plot.mkinfit</a>, <a href='parms.html'>parms</a> and <a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a>.</p> + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p><a href="summary.mkinfit.html">summary.mkinfit</a>, <a href="plot.mkinfit.html">plot.mkinfit</a>, <a href="parms.html">parms</a> and <a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a>.</p> <p>Comparisons of models fitted to the same data can be made using -<code><a href='https://rdrr.io/r/stats/AIC.html'>AIC</a></code> by virtue of the method <code><a href='logLik.mkinfit.html'>logLik.mkinfit</a></code>.</p> +<code><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">AIC</a></code> by virtue of the method <code><a href="logLik.mkinfit.html">logLik.mkinfit</a></code>.</p> <p>Fitting of several models to several datasets in a single call to -<code><a href='mmkin.html'>mmkin</a></code>.</p></div> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - +<code><a href="mmkin.html">mmkin</a></code>.</p></div> + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='co'># Use shorthand notation for parent only degradation</span> -<span class='va'>fit</span> <span class='op'><-</span> <span class='fu'>mkinfit</span><span class='op'>(</span><span class='st'>"FOMC"</span>, <span class='va'>FOCUS_2006_C</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span> -</div><div class='output co'>#> mkin version used for fitting: 1.0.4 -#> R version used for fitting: 4.0.4 -#> Date of fit: Wed Mar 31 19:15:41 2021 -#> Date of summary: Wed Mar 31 19:15:41 2021 -#> -#> Equations: -#> d_parent/dt = - (alpha/beta) * 1/((time/beta) + 1) * parent -#> -#> Model predictions using solution type analytical -#> -#> Fitted using 222 model solutions performed in 0.046 s -#> -#> Error model: Constant variance -#> -#> Error model algorithm: OLS -#> -#> Starting values for parameters to be optimised: -#> value type -#> parent_0 85.1 state -#> alpha 1.0 deparm -#> beta 10.0 deparm -#> -#> Starting values for the transformed parameters actually optimised: -#> value lower upper -#> parent_0 85.100000 -Inf Inf -#> log_alpha 0.000000 -Inf Inf -#> log_beta 2.302585 -Inf Inf -#> -#> Fixed parameter values: -#> None -#> -#> Results: -#> -#> AIC BIC logLik -#> 44.68652 45.47542 -18.34326 -#> -#> Optimised, transformed parameters with symmetric confidence intervals: -#> Estimate Std. Error Lower Upper -#> parent_0 85.87000 1.8070 81.23000 90.5200 -#> log_alpha 0.05192 0.1353 -0.29580 0.3996 -#> log_beta 0.65100 0.2287 0.06315 1.2390 -#> sigma 1.85700 0.4378 0.73200 2.9830 -#> -#> Parameter correlation: -#> parent_0 log_alpha log_beta sigma -#> parent_0 1.000e+00 -1.565e-01 -3.142e-01 4.772e-08 -#> log_alpha -1.565e-01 1.000e+00 9.564e-01 1.005e-07 -#> log_beta -3.142e-01 9.564e-01 1.000e+00 8.541e-08 -#> sigma 4.772e-08 1.005e-07 8.541e-08 1.000e+00 -#> -#> Backtransformed parameters: -#> Confidence intervals for internally transformed parameters are asymmetric. -#> t-test (unrealistically) based on the assumption of normal distribution -#> for estimators of untransformed parameters. -#> Estimate t value Pr(>t) Lower Upper -#> parent_0 85.870 47.530 3.893e-08 81.2300 90.520 -#> alpha 1.053 7.393 3.562e-04 0.7439 1.491 -#> beta 1.917 4.373 3.601e-03 1.0650 3.451 -#> sigma 1.857 4.243 4.074e-03 0.7320 2.983 -#> -#> FOCUS Chi2 error levels in percent: -#> err.min n.optim df -#> All data 6.657 3 6 -#> parent 6.657 3 6 -#> -#> Estimated disappearance times: -#> DT50 DT90 DT50back -#> parent 1.785 15.15 4.56 -#> -#> Data: -#> time variable observed predicted residual -#> 0 parent 85.1 85.875 -0.7749 -#> 1 parent 57.9 55.191 2.7091 -#> 3 parent 29.9 31.845 -1.9452 -#> 7 parent 14.6 17.012 -2.4124 -#> 14 parent 9.7 9.241 0.4590 -#> 28 parent 6.6 4.754 1.8460 -#> 63 parent 4.0 2.102 1.8977 -#> 91 parent 3.9 1.441 2.4590 -#> 119 parent 0.6 1.092 -0.4919</div><div class='input'> -<span class='co'># One parent compound, one metabolite, both single first order.</span> -<span class='co'># We remove zero values from FOCUS dataset D in order to avoid warnings</span> -<span class='va'>FOCUS_D</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/subset.html'>subset</a></span><span class='op'>(</span><span class='va'>FOCUS_2006_D</span>, <span class='va'>value</span> <span class='op'>!=</span> <span class='fl'>0</span><span class='op'>)</span> -<span class='co'># Use mkinsub for convenience in model formulation. Pathway to sink included per default.</span> -<span class='va'>SFO_SFO</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"m1"</span><span class='op'>)</span>, - m1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> -<span class='co'># Fit the model quietly to the FOCUS example dataset D using defaults</span> -<span class='va'>fit</span> <span class='op'><-</span> <span class='fu'>mkinfit</span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'><a href='plot.mkinfit.html'>plot_sep</a></span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span> -</div><div class='img'><img src='mkinfit-1.png' alt='' width='700' height='433' /></div><div class='input'><span class='co'># As lower parent values appear to have lower variance, we try an alternative error model</span> -<span class='va'>fit.tc</span> <span class='op'><-</span> <span class='fu'>mkinfit</span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span><span class='op'>)</span> -<span class='co'># This avoids the warning, and the likelihood ratio test confirms it is preferable</span> -<span class='fu'><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a></span><span class='op'>(</span><span class='va'>fit.tc</span>, <span class='va'>fit</span><span class='op'>)</span> -</div><div class='output co'>#> Likelihood ratio test -#> -#> Model 1: SFO_SFO with error model tc and fixed parameter(s) m1_0 -#> Model 2: SFO_SFO with error model const and fixed parameter(s) m1_0 -#> #Df LogLik Df Chisq Pr(>Chisq) -#> 1 6 -64.983 -#> 2 5 -97.224 -1 64.483 9.737e-16 *** -#> --- -#> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</div><div class='input'><span class='co'># We can also allow for different variances of parent and metabolite as error model</span> -<span class='va'>fit.obs</span> <span class='op'><-</span> <span class='fu'>mkinfit</span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, error_model <span class='op'>=</span> <span class='st'>"obs"</span><span class='op'>)</span> -<span class='co'># The two-component error model has significantly higher likelihood</span> -<span class='fu'><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a></span><span class='op'>(</span><span class='va'>fit.obs</span>, <span class='va'>fit.tc</span><span class='op'>)</span> -</div><div class='output co'>#> Likelihood ratio test -#> -#> Model 1: SFO_SFO with error model tc and fixed parameter(s) m1_0 -#> Model 2: SFO_SFO with error model obs and fixed parameter(s) m1_0 -#> #Df LogLik Df Chisq Pr(>Chisq) -#> 1 6 -64.983 -#> 2 6 -96.936 0 63.907 < 2.2e-16 *** -#> --- -#> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</div><div class='input'><span class='fu'><a href='parms.html'>parms</a></span><span class='op'>(</span><span class='va'>fit.tc</span><span class='op'>)</span> -</div><div class='output co'>#> parent_0 k_parent k_m1 f_parent_to_m1 sigma_low -#> 1.007343e+02 1.005562e-01 5.166712e-03 5.083933e-01 3.049883e-03 -#> rsd_high -#> 7.928118e-02 </div><div class='input'><span class='fu'><a href='endpoints.html'>endpoints</a></span><span class='op'>(</span><span class='va'>fit.tc</span><span class='op'>)</span> -</div><div class='output co'>#> $ff -#> parent_m1 parent_sink -#> 0.5083933 0.4916067 -#> -#> $distimes -#> DT50 DT90 -#> parent 6.89313 22.89848 -#> m1 134.15634 445.65772 -#> </div><div class='input'> -<span class='co'># We can show a quick (only one replication) benchmark for this case, as we</span> -<span class='co'># have several alternative solution methods for the model. We skip</span> -<span class='co'># uncompiled deSolve, as it is so slow. More benchmarks are found in the</span> -<span class='co'># benchmark vignette</span> -<span class='co'># \dontrun{</span> -<span class='kw'>if</span><span class='op'>(</span><span class='kw'><a href='https://rdrr.io/r/base/library.html'>require</a></span><span class='op'>(</span><span class='va'><a href='http://rbenchmark.googlecode.com'>rbenchmark</a></span><span class='op'>)</span><span class='op'>)</span> <span class='op'>{</span> - <span class='fu'><a href='https://rdrr.io/pkg/rbenchmark/man/benchmark.html'>benchmark</a></span><span class='op'>(</span>replications <span class='op'>=</span> <span class='fl'>1</span>, order <span class='op'>=</span> <span class='st'>"relative"</span>, columns <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"test"</span>, <span class='st'>"relative"</span>, <span class='st'>"elapsed"</span><span class='op'>)</span>, - deSolve_compiled <span class='op'>=</span> <span class='fu'>mkinfit</span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span>, - solution_type <span class='op'>=</span> <span class='st'>"deSolve"</span>, use_compiled <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span>, - eigen <span class='op'>=</span> <span class='fu'>mkinfit</span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span>, - solution_type <span class='op'>=</span> <span class='st'>"eigen"</span><span class='op'>)</span>, - analytical <span class='op'>=</span> <span class='fu'>mkinfit</span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span>, - solution_type <span class='op'>=</span> <span class='st'>"analytical"</span><span class='op'>)</span><span class='op'>)</span> -<span class='op'>}</span> -</div><div class='output co'>#> <span class='message'>Loading required package: rbenchmark</span></div><div class='output co'>#> test relative elapsed -#> 3 analytical 1.000 0.547 -#> 1 deSolve_compiled 1.717 0.939 -#> 2 eigen 2.644 1.446</div><div class='input'><span class='co'># }</span> - -<span class='co'># Use stepwise fitting, using optimised parameters from parent only fit, FOMC-SFO</span> -<span class='co'># \dontrun{</span> -<span class='va'>FOMC_SFO</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"FOMC"</span>, <span class='st'>"m1"</span><span class='op'>)</span>, - m1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'><span class='va'>fit.FOMC_SFO</span> <span class='op'><-</span> <span class='fu'>mkinfit</span><span class='op'>(</span><span class='va'>FOMC_SFO</span>, <span class='va'>FOCUS_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='co'># Again, we get a warning and try a more sophisticated error model</span> -<span class='va'>fit.FOMC_SFO.tc</span> <span class='op'><-</span> <span class='fu'>mkinfit</span><span class='op'>(</span><span class='va'>FOMC_SFO</span>, <span class='va'>FOCUS_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span><span class='op'>)</span> -<span class='co'># This model has a higher likelihood, but not significantly so</span> -<span class='fu'><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a></span><span class='op'>(</span><span class='va'>fit.tc</span>, <span class='va'>fit.FOMC_SFO.tc</span><span class='op'>)</span> -</div><div class='output co'>#> Likelihood ratio test -#> -#> Model 1: FOMC_SFO with error model tc and fixed parameter(s) m1_0 -#> Model 2: SFO_SFO with error model tc and fixed parameter(s) m1_0 -#> #Df LogLik Df Chisq Pr(>Chisq) -#> 1 7 -64.829 -#> 2 6 -64.983 -1 0.3075 0.5792</div><div class='input'><span class='co'># Also, the missing standard error for log_beta and the t-tests for alpha</span> -<span class='co'># and beta indicate overparameterisation</span> -<span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>fit.FOMC_SFO.tc</span>, data <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='warning'>Warning: NaNs produced</span></div><div class='output co'>#> <span class='warning'>Warning: NaNs produced</span></div><div class='output co'>#> <span class='warning'>Warning: diag(.) had 0 or NA entries; non-finite result is doubtful</span></div><div class='output co'>#> mkin version used for fitting: 1.0.4 -#> R version used for fitting: 4.0.4 -#> Date of fit: Wed Mar 31 19:15:53 2021 -#> Date of summary: Wed Mar 31 19:15:53 2021 -#> -#> Equations: -#> d_parent/dt = - (alpha/beta) * 1/((time/beta) + 1) * parent -#> d_m1/dt = + f_parent_to_m1 * (alpha/beta) * 1/((time/beta) + 1) * -#> parent - k_m1 * m1 -#> -#> Model predictions using solution type deSolve -#> -#> Fitted using 3729 model solutions performed in 2.798 s -#> -#> Error model: Two-component variance function -#> -#> Error model algorithm: d_3 -#> Direct fitting and three-step fitting yield approximately the same likelihood -#> -#> Starting values for parameters to be optimised: -#> value type -#> parent_0 100.75 state -#> alpha 1.00 deparm -#> beta 10.00 deparm -#> k_m1 0.10 deparm -#> f_parent_to_m1 0.50 deparm -#> sigma_low 0.10 error -#> rsd_high 0.10 error -#> -#> Starting values for the transformed parameters actually optimised: -#> value lower upper -#> parent_0 100.750000 -Inf Inf -#> log_k_m1 -2.302585 -Inf Inf -#> f_parent_qlogis 0.000000 -Inf Inf -#> log_alpha 0.000000 -Inf Inf -#> log_beta 2.302585 -Inf Inf -#> sigma_low 0.100000 0 Inf -#> rsd_high 0.100000 0 Inf -#> -#> Fixed parameter values: -#> value type -#> m1_0 0 state -#> -#> Results: -#> -#> AIC BIC logLik -#> 143.658 155.1211 -64.82902 -#> -#> Optimised, transformed parameters with symmetric confidence intervals: -#> Estimate Std. Error Lower Upper -#> parent_0 101.600000 2.6400000 96.240000 107.000000 -#> log_k_m1 -5.284000 0.0929100 -5.474000 -5.095000 -#> f_parent_qlogis 0.001426 0.0767000 -0.155000 0.157800 -#> log_alpha 5.522000 0.0077320 5.506000 5.538000 -#> log_beta 7.806000 NaN NaN NaN -#> sigma_low 0.002488 0.0002431 0.001992 0.002984 -#> rsd_high 0.079210 0.0093280 0.060180 0.098230 -#> -#> Parameter correlation: -#> parent_0 log_k_m1 f_parent_qlogis log_alpha log_beta -#> parent_0 1.000000 -0.095226 -0.76678 0.70544 NaN -#> log_k_m1 -0.095226 1.000000 0.51432 -0.14387 NaN -#> f_parent_qlogis -0.766780 0.514321 1.00000 -0.61396 NaN -#> log_alpha 0.705444 -0.143872 -0.61396 1.00000 NaN -#> log_beta NaN NaN NaN NaN 1 -#> sigma_low 0.016073 0.001586 0.01548 5.87007 NaN -#> rsd_high 0.006626 -0.011700 -0.05357 0.04849 NaN -#> sigma_low rsd_high -#> parent_0 0.016073 0.006626 -#> log_k_m1 0.001586 -0.011700 -#> f_parent_qlogis 0.015476 -0.053566 -#> log_alpha 5.870075 0.048487 -#> log_beta NaN NaN -#> sigma_low 1.000000 -0.652558 -#> rsd_high -0.652558 1.000000 -#> -#> Backtransformed parameters: -#> Confidence intervals for internally transformed parameters are asymmetric. -#> t-test (unrealistically) based on the assumption of normal distribution -#> for estimators of untransformed parameters. -#> Estimate t value Pr(>t) Lower Upper -#> parent_0 1.016e+02 32.7800 6.311e-26 9.624e+01 1.070e+02 -#> k_m1 5.072e-03 10.1200 1.216e-11 4.196e-03 6.130e-03 -#> f_parent_to_m1 5.004e-01 20.8300 4.317e-20 4.613e-01 5.394e-01 -#> alpha 2.502e+02 0.5624 2.889e-01 2.463e+02 2.542e+02 -#> beta 2.455e+03 0.5549 2.915e-01 NA NA -#> sigma_low 2.488e-03 0.4843 3.158e-01 1.992e-03 2.984e-03 -#> rsd_high 7.921e-02 8.4300 8.001e-10 6.018e-02 9.823e-02 -#> -#> FOCUS Chi2 error levels in percent: -#> err.min n.optim df -#> All data 6.781 5 14 -#> parent 7.141 3 6 -#> m1 4.640 2 8 -#> -#> Resulting formation fractions: -#> ff -#> parent_m1 0.5004 -#> parent_sink 0.4996 -#> -#> Estimated disappearance times: -#> DT50 DT90 DT50back -#> parent 6.812 22.7 6.834 -#> m1 136.661 454.0 NA</div><div class='input'> -<span class='co'># We can easily use starting parameters from the parent only fit (only for illustration)</span> -<span class='va'>fit.FOMC</span> <span class='op'>=</span> <span class='fu'>mkinfit</span><span class='op'>(</span><span class='st'>"FOMC"</span>, <span class='va'>FOCUS_2006_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span><span class='op'>)</span> -<span class='va'>fit.FOMC_SFO</span> <span class='op'><-</span> <span class='fu'>mkinfit</span><span class='op'>(</span><span class='va'>FOMC_SFO</span>, <span class='va'>FOCUS_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, - parms.ini <span class='op'>=</span> <span class='va'>fit.FOMC</span><span class='op'>$</span><span class='va'>bparms.ode</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span><span class='op'>)</span> -<span class='co'># }</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="co"># Use shorthand notation for parent only degradation</span></span> +<span class="r-in"><span class="va">fit</span> <span class="op"><-</span> <span class="fu">mkinfit</span><span class="op">(</span><span class="st">"FOMC"</span>, <span class="va">FOCUS_2006_C</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/summary.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> mkin version used for fitting: 1.1.0 </span> +<span class="r-out co"><span class="r-pr">#></span> R version used for fitting: 4.1.2 </span> +<span class="r-out co"><span class="r-pr">#></span> Date of fit: Wed Mar 2 13:30:39 2022 </span> +<span class="r-out co"><span class="r-pr">#></span> Date of summary: Wed Mar 2 13:30:39 2022 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Equations:</span> +<span class="r-out co"><span class="r-pr">#></span> d_parent/dt = - (alpha/beta) * 1/((time/beta) + 1) * parent</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model predictions using solution type analytical </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fitted using 222 model solutions performed in 0.046 s</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Error model: Constant variance </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Error model algorithm: OLS </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Starting values for parameters to be optimised:</span> +<span class="r-out co"><span class="r-pr">#></span> value type</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 85.1 state</span> +<span class="r-out co"><span class="r-pr">#></span> alpha 1.0 deparm</span> +<span class="r-out co"><span class="r-pr">#></span> beta 10.0 deparm</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Starting values for the transformed parameters actually optimised:</span> +<span class="r-out co"><span class="r-pr">#></span> value lower upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 85.100000 -Inf Inf</span> +<span class="r-out co"><span class="r-pr">#></span> log_alpha 0.000000 -Inf Inf</span> +<span class="r-out co"><span class="r-pr">#></span> log_beta 2.302585 -Inf Inf</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fixed parameter values:</span> +<span class="r-out co"><span class="r-pr">#></span> None</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Results:</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> AIC BIC logLik</span> +<span class="r-out co"><span class="r-pr">#></span> 44.68652 45.47542 -18.34326</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Optimised, transformed parameters with symmetric confidence intervals:</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Std. Error Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 85.87000 1.8070 81.23000 90.5200</span> +<span class="r-out co"><span class="r-pr">#></span> log_alpha 0.05192 0.1353 -0.29580 0.3996</span> +<span class="r-out co"><span class="r-pr">#></span> log_beta 0.65100 0.2287 0.06315 1.2390</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 1.85700 0.4378 0.73200 2.9830</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Parameter correlation:</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_alpha log_beta sigma</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 1.000e+00 -1.565e-01 -3.142e-01 4.772e-08</span> +<span class="r-out co"><span class="r-pr">#></span> log_alpha -1.565e-01 1.000e+00 9.564e-01 1.005e-07</span> +<span class="r-out co"><span class="r-pr">#></span> log_beta -3.142e-01 9.564e-01 1.000e+00 8.541e-08</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 4.772e-08 1.005e-07 8.541e-08 1.000e+00</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Backtransformed parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> Confidence intervals for internally transformed parameters are asymmetric.</span> +<span class="r-out co"><span class="r-pr">#></span> t-test (unrealistically) based on the assumption of normal distribution</span> +<span class="r-out co"><span class="r-pr">#></span> for estimators of untransformed parameters.</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate t value Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 85.870 47.530 3.893e-08 81.2300 90.520</span> +<span class="r-out co"><span class="r-pr">#></span> alpha 1.053 7.393 3.562e-04 0.7439 1.491</span> +<span class="r-out co"><span class="r-pr">#></span> beta 1.917 4.373 3.601e-03 1.0650 3.451</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 1.857 4.243 4.074e-03 0.7320 2.983</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> FOCUS Chi2 error levels in percent:</span> +<span class="r-out co"><span class="r-pr">#></span> err.min n.optim df</span> +<span class="r-out co"><span class="r-pr">#></span> All data 6.657 3 6</span> +<span class="r-out co"><span class="r-pr">#></span> parent 6.657 3 6</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Estimated disappearance times:</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90 DT50back</span> +<span class="r-out co"><span class="r-pr">#></span> parent 1.785 15.15 4.56</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Data:</span> +<span class="r-out co"><span class="r-pr">#></span> time variable observed predicted residual</span> +<span class="r-out co"><span class="r-pr">#></span> 0 parent 85.1 85.875 -0.7749</span> +<span class="r-out co"><span class="r-pr">#></span> 1 parent 57.9 55.191 2.7091</span> +<span class="r-out co"><span class="r-pr">#></span> 3 parent 29.9 31.845 -1.9452</span> +<span class="r-out co"><span class="r-pr">#></span> 7 parent 14.6 17.012 -2.4124</span> +<span class="r-out co"><span class="r-pr">#></span> 14 parent 9.7 9.241 0.4590</span> +<span class="r-out co"><span class="r-pr">#></span> 28 parent 6.6 4.754 1.8460</span> +<span class="r-out co"><span class="r-pr">#></span> 63 parent 4.0 2.102 1.8977</span> +<span class="r-out co"><span class="r-pr">#></span> 91 parent 3.9 1.441 2.4590</span> +<span class="r-out co"><span class="r-pr">#></span> 119 parent 0.6 1.092 -0.4919</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># One parent compound, one metabolite, both single first order.</span></span> +<span class="r-in"><span class="co"># We remove zero values from FOCUS dataset D in order to avoid warnings</span></span> +<span class="r-in"><span class="va">FOCUS_D</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">FOCUS_2006_D</span>, <span class="va">value</span> <span class="op">!=</span> <span class="fl">0</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># Use mkinsub for convenience in model formulation. Pathway to sink included per default.</span></span> +<span class="r-in"><span class="va">SFO_SFO</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"m1"</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Fit the model quietly to the FOCUS example dataset D using defaults</span></span> +<span class="r-in"><span class="va">fit</span> <span class="op"><-</span> <span class="fu">mkinfit</span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="plot.mkinfit.html">plot_sep</a></span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></span> +<span class="r-plt img"><img src="mkinfit-1.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="co"># As lower parent values appear to have lower variance, we try an alternative error model</span></span> +<span class="r-in"><span class="va">fit.tc</span> <span class="op"><-</span> <span class="fu">mkinfit</span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"tc"</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># This avoids the warning, and the likelihood ratio test confirms it is preferable</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a></span><span class="op">(</span><span class="va">fit.tc</span>, <span class="va">fit</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Likelihood ratio test</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model 1: SFO_SFO with error model tc and fixed parameter(s) m1_0</span> +<span class="r-out co"><span class="r-pr">#></span> Model 2: SFO_SFO with error model const and fixed parameter(s) m1_0</span> +<span class="r-out co"><span class="r-pr">#></span> #Df LogLik Df Chisq Pr(>Chisq) </span> +<span class="r-out co"><span class="r-pr">#></span> 1 6 -64.983 </span> +<span class="r-out co"><span class="r-pr">#></span> 2 5 -97.224 -1 64.483 9.737e-16 ***</span> +<span class="r-out co"><span class="r-pr">#></span> ---</span> +<span class="r-out co"><span class="r-pr">#></span> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</span> +<span class="r-in"><span class="co"># We can also allow for different variances of parent and metabolite as error model</span></span> +<span class="r-in"><span class="va">fit.obs</span> <span class="op"><-</span> <span class="fu">mkinfit</span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"obs"</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># The two-component error model has significantly higher likelihood</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a></span><span class="op">(</span><span class="va">fit.obs</span>, <span class="va">fit.tc</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Likelihood ratio test</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model 1: SFO_SFO with error model tc and fixed parameter(s) m1_0</span> +<span class="r-out co"><span class="r-pr">#></span> Model 2: SFO_SFO with error model obs and fixed parameter(s) m1_0</span> +<span class="r-out co"><span class="r-pr">#></span> #Df LogLik Df Chisq Pr(>Chisq) </span> +<span class="r-out co"><span class="r-pr">#></span> 1 6 -64.983 </span> +<span class="r-out co"><span class="r-pr">#></span> 2 6 -96.936 0 63.907 < 2.2e-16 ***</span> +<span class="r-out co"><span class="r-pr">#></span> ---</span> +<span class="r-out co"><span class="r-pr">#></span> Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1</span> +<span class="r-in"><span class="fu"><a href="parms.html">parms</a></span><span class="op">(</span><span class="va">fit.tc</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 k_parent k_m1 f_parent_to_m1 sigma_low </span> +<span class="r-out co"><span class="r-pr">#></span> 1.007343e+02 1.005562e-01 5.166712e-03 5.083933e-01 3.049883e-03 </span> +<span class="r-out co"><span class="r-pr">#></span> rsd_high </span> +<span class="r-out co"><span class="r-pr">#></span> 7.928118e-02 </span> +<span class="r-in"><span class="fu"><a href="endpoints.html">endpoints</a></span><span class="op">(</span><span class="va">fit.tc</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> $ff</span> +<span class="r-out co"><span class="r-pr">#></span> parent_m1 parent_sink </span> +<span class="r-out co"><span class="r-pr">#></span> 0.5083933 0.4916067 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $distimes</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90</span> +<span class="r-out co"><span class="r-pr">#></span> parent 6.89313 22.89848</span> +<span class="r-out co"><span class="r-pr">#></span> m1 134.15634 445.65772</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># We can show a quick (only one replication) benchmark for this case, as we</span></span> +<span class="r-in"><span class="co"># have several alternative solution methods for the model. We skip</span></span> +<span class="r-in"><span class="co"># uncompiled deSolve, as it is so slow. More benchmarks are found in the</span></span> +<span class="r-in"><span class="co"># benchmark vignette</span></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="kw">if</span><span class="op">(</span><span class="kw"><a href="https://rdrr.io/r/base/library.html" class="external-link">require</a></span><span class="op">(</span><span class="va"><a href="http://rbenchmark.googlecode.com" class="external-link">rbenchmark</a></span><span class="op">)</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/pkg/rbenchmark/man/benchmark.html" class="external-link">benchmark</a></span><span class="op">(</span>replications <span class="op">=</span> <span class="fl">1</span>, order <span class="op">=</span> <span class="st">"relative"</span>, columns <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"test"</span>, <span class="st">"relative"</span>, <span class="st">"elapsed"</span><span class="op">)</span>,</span> +<span class="r-in"> deSolve_compiled <span class="op">=</span> <span class="fu">mkinfit</span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"tc"</span>,</span> +<span class="r-in"> solution_type <span class="op">=</span> <span class="st">"deSolve"</span>, use_compiled <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span>,</span> +<span class="r-in"> eigen <span class="op">=</span> <span class="fu">mkinfit</span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"tc"</span>,</span> +<span class="r-in"> solution_type <span class="op">=</span> <span class="st">"eigen"</span><span class="op">)</span>,</span> +<span class="r-in"> analytical <span class="op">=</span> <span class="fu">mkinfit</span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"tc"</span>,</span> +<span class="r-in"> solution_type <span class="op">=</span> <span class="st">"analytical"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="op">}</span></span> +<span class="r-out co"><span class="r-pr">#></span> test relative elapsed</span> +<span class="r-out co"><span class="r-pr">#></span> 3 analytical 1.000 0.699</span> +<span class="r-out co"><span class="r-pr">#></span> 1 deSolve_compiled 1.595 1.115</span> +<span class="r-out co"><span class="r-pr">#></span> 2 eigen 2.252 1.574</span> +<span class="r-in"><span class="co"># }</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Use stepwise fitting, using optimised parameters from parent only fit, FOMC-SFO</span></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="va">FOMC_SFO</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"FOMC"</span>, <span class="st">"m1"</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="va">fit.FOMC_SFO</span> <span class="op"><-</span> <span class="fu">mkinfit</span><span class="op">(</span><span class="va">FOMC_SFO</span>, <span class="va">FOCUS_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># Again, we get a warning and try a more sophisticated error model</span></span> +<span class="r-in"><span class="va">fit.FOMC_SFO.tc</span> <span class="op"><-</span> <span class="fu">mkinfit</span><span class="op">(</span><span class="va">FOMC_SFO</span>, <span class="va">FOCUS_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"tc"</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># This model has a higher likelihood, but not significantly so</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a></span><span class="op">(</span><span class="va">fit.tc</span>, <span class="va">fit.FOMC_SFO.tc</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Likelihood ratio test</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model 1: FOMC_SFO with error model tc and fixed parameter(s) m1_0</span> +<span class="r-out co"><span class="r-pr">#></span> Model 2: SFO_SFO with error model tc and fixed parameter(s) m1_0</span> +<span class="r-out co"><span class="r-pr">#></span> #Df LogLik Df Chisq Pr(>Chisq)</span> +<span class="r-out co"><span class="r-pr">#></span> 1 7 -64.829 </span> +<span class="r-out co"><span class="r-pr">#></span> 2 6 -64.983 -1 0.3075 0.5792</span> +<span class="r-in"><span class="co"># Also, the missing standard error for log_beta and the t-tests for alpha</span></span> +<span class="r-in"><span class="co"># and beta indicate overparameterisation</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/summary.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">fit.FOMC_SFO.tc</span>, data <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> mkin version used for fitting: 1.1.0 </span> +<span class="r-out co"><span class="r-pr">#></span> R version used for fitting: 4.1.2 </span> +<span class="r-out co"><span class="r-pr">#></span> Date of fit: Wed Mar 2 13:30:53 2022 </span> +<span class="r-out co"><span class="r-pr">#></span> Date of summary: Wed Mar 2 13:30:53 2022 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Equations:</span> +<span class="r-out co"><span class="r-pr">#></span> d_parent/dt = - (alpha/beta) * 1/((time/beta) + 1) * parent</span> +<span class="r-out co"><span class="r-pr">#></span> d_m1/dt = + f_parent_to_m1 * (alpha/beta) * 1/((time/beta) + 1) *</span> +<span class="r-out co"><span class="r-pr">#></span> parent - k_m1 * m1</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model predictions using solution type deSolve </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fitted using 3729 model solutions performed in 2.916 s</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Error model: Two-component variance function </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Error model algorithm: d_3 </span> +<span class="r-out co"><span class="r-pr">#></span> Direct fitting and three-step fitting yield approximately the same likelihood </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Starting values for parameters to be optimised:</span> +<span class="r-out co"><span class="r-pr">#></span> value type</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 100.75 state</span> +<span class="r-out co"><span class="r-pr">#></span> alpha 1.00 deparm</span> +<span class="r-out co"><span class="r-pr">#></span> beta 10.00 deparm</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1 0.10 deparm</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_m1 0.50 deparm</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low 0.10 error</span> +<span class="r-out co"><span class="r-pr">#></span> rsd_high 0.10 error</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Starting values for the transformed parameters actually optimised:</span> +<span class="r-out co"><span class="r-pr">#></span> value lower upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 100.750000 -Inf Inf</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_m1 -2.302585 -Inf Inf</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_qlogis 0.000000 -Inf Inf</span> +<span class="r-out co"><span class="r-pr">#></span> log_alpha 0.000000 -Inf Inf</span> +<span class="r-out co"><span class="r-pr">#></span> log_beta 2.302585 -Inf Inf</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low 0.100000 0 Inf</span> +<span class="r-out co"><span class="r-pr">#></span> rsd_high 0.100000 0 Inf</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fixed parameter values:</span> +<span class="r-out co"><span class="r-pr">#></span> value type</span> +<span class="r-out co"><span class="r-pr">#></span> m1_0 0 state</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Results:</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> AIC BIC logLik</span> +<span class="r-out co"><span class="r-pr">#></span> 143.658 155.1211 -64.82902</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Optimised, transformed parameters with symmetric confidence intervals:</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Std. Error Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 101.600000 2.6400000 96.240000 107.000000</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_m1 -5.284000 0.0929100 -5.474000 -5.095000</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_qlogis 0.001426 0.0767000 -0.155000 0.157800</span> +<span class="r-out co"><span class="r-pr">#></span> log_alpha 5.522000 0.0077320 5.506000 5.538000</span> +<span class="r-out co"><span class="r-pr">#></span> log_beta 7.806000 NaN NaN NaN</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low 0.002488 0.0002431 0.001992 0.002984</span> +<span class="r-out co"><span class="r-pr">#></span> rsd_high 0.079210 0.0093280 0.060180 0.098230</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Parameter correlation:</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_k_m1 f_parent_qlogis log_alpha log_beta</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 1.000000 -0.095226 -0.76678 0.70544 NaN</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_m1 -0.095226 1.000000 0.51432 -0.14387 NaN</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_qlogis -0.766780 0.514321 1.00000 -0.61396 NaN</span> +<span class="r-out co"><span class="r-pr">#></span> log_alpha 0.705444 -0.143872 -0.61396 1.00000 NaN</span> +<span class="r-out co"><span class="r-pr">#></span> log_beta NaN NaN NaN NaN 1</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low 0.016073 0.001586 0.01548 5.87007 NaN</span> +<span class="r-out co"><span class="r-pr">#></span> rsd_high 0.006626 -0.011700 -0.05357 0.04849 NaN</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low rsd_high</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 0.016073 0.006626</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_m1 0.001586 -0.011700</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_qlogis 0.015476 -0.053566</span> +<span class="r-out co"><span class="r-pr">#></span> log_alpha 5.870075 0.048487</span> +<span class="r-out co"><span class="r-pr">#></span> log_beta NaN NaN</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low 1.000000 -0.652558</span> +<span class="r-out co"><span class="r-pr">#></span> rsd_high -0.652558 1.000000</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Backtransformed parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> Confidence intervals for internally transformed parameters are asymmetric.</span> +<span class="r-out co"><span class="r-pr">#></span> t-test (unrealistically) based on the assumption of normal distribution</span> +<span class="r-out co"><span class="r-pr">#></span> for estimators of untransformed parameters.</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate t value Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 1.016e+02 32.7800 6.311e-26 9.624e+01 1.070e+02</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1 5.072e-03 10.1200 1.216e-11 4.196e-03 6.130e-03</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_m1 5.004e-01 20.8300 4.317e-20 4.613e-01 5.394e-01</span> +<span class="r-out co"><span class="r-pr">#></span> alpha 2.502e+02 0.5624 2.889e-01 2.463e+02 2.542e+02</span> +<span class="r-out co"><span class="r-pr">#></span> beta 2.455e+03 0.5549 2.915e-01 NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low 2.488e-03 0.4843 3.158e-01 1.992e-03 2.984e-03</span> +<span class="r-out co"><span class="r-pr">#></span> rsd_high 7.921e-02 8.4300 8.001e-10 6.018e-02 9.823e-02</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> FOCUS Chi2 error levels in percent:</span> +<span class="r-out co"><span class="r-pr">#></span> err.min n.optim df</span> +<span class="r-out co"><span class="r-pr">#></span> All data 6.781 5 14</span> +<span class="r-out co"><span class="r-pr">#></span> parent 7.141 3 6</span> +<span class="r-out co"><span class="r-pr">#></span> m1 4.640 2 8</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Resulting formation fractions:</span> +<span class="r-out co"><span class="r-pr">#></span> ff</span> +<span class="r-out co"><span class="r-pr">#></span> parent_m1 0.5004</span> +<span class="r-out co"><span class="r-pr">#></span> parent_sink 0.4996</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Estimated disappearance times:</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90 DT50back</span> +<span class="r-out co"><span class="r-pr">#></span> parent 6.812 22.7 6.834</span> +<span class="r-out co"><span class="r-pr">#></span> m1 136.661 454.0 NA</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># We can easily use starting parameters from the parent only fit (only for illustration)</span></span> +<span class="r-in"><span class="va">fit.FOMC</span> <span class="op">=</span> <span class="fu">mkinfit</span><span class="op">(</span><span class="st">"FOMC"</span>, <span class="va">FOCUS_2006_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"tc"</span><span class="op">)</span></span> +<span class="r-in"><span class="va">fit.FOMC_SFO</span> <span class="op"><-</span> <span class="fu">mkinfit</span><span class="op">(</span><span class="va">FOMC_SFO</span>, <span class="va">FOCUS_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>,</span> +<span class="r-in"> parms.ini <span class="op">=</span> <span class="va">fit.FOMC</span><span class="op">$</span><span class="va">bparms.ode</span>, error_model <span class="op">=</span> <span class="st">"tc"</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/mkinmod.html b/docs/reference/mkinmod.html index f9976c6b..a5cc3d7a 100644 --- a/docs/reference/mkinmod.html +++ b/docs/reference/mkinmod.html @@ -1,73 +1,16 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Function to set up a kinetic model with one or more state variables — mkinmod • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Function to set up a kinetic model with one or more state variables — mkinmod" /> -<meta property="og:description" content="This function is usually called using a call to mkinsub() for each observed +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Function to set up a kinetic model with one or more state variables — mkinmod • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Function to set up a kinetic model with one or more state variables — mkinmod"><meta property="og:description" content="This function is usually called using a call to mkinsub() for each observed variable, specifying the corresponding submodel as well as outgoing pathways (see examples). Print mkinmod objects in a way that the user finds his way to get to its -components. -This is a convenience function to set up the lists used as arguments for -mkinmod." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +components."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -78,13 +21,12 @@ mkinmod." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.5</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -93,8 +35,7 @@ mkinmod." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -104,6 +45,9 @@ mkinmod." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -118,34 +62,27 @@ mkinmod." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Function to set up a kinetic model with one or more state variables</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/mkinmod.R'><code>R/mkinmod.R</code></a>, <a href='https://github.com/jranke/mkin/blob/master/R/mkinsub.R'><code>R/mkinsub.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/mkinmod.R" class="external-link"><code>R/mkinmod.R</code></a>, <a href="https://github.com/jranke/mkin/blob/HEAD/R/mkinsub.R" class="external-link"><code>R/mkinsub.R</code></a></small> <div class="hidden name"><code>mkinmod.Rd</code></div> </div> @@ -155,33 +92,31 @@ variable, specifying the corresponding submodel as well as outgoing pathways (see examples).</p> <p>Print mkinmod objects in a way that the user finds his way to get to its components.</p> -<p>This is a convenience function to set up the lists used as arguments for -<code>mkinmod</code>.</p> </div> - <pre class="usage"><span class='fu'>mkinmod</span><span class='op'>(</span> - <span class='va'>...</span>, - use_of_ff <span class='op'>=</span> <span class='st'>"max"</span>, - name <span class='op'>=</span> <span class='cn'>NULL</span>, - speclist <span class='op'>=</span> <span class='cn'>NULL</span>, - quiet <span class='op'>=</span> <span class='cn'>FALSE</span>, - verbose <span class='op'>=</span> <span class='cn'>FALSE</span>, - dll_dir <span class='op'>=</span> <span class='cn'>NULL</span>, - unload <span class='op'>=</span> <span class='cn'>FALSE</span>, - overwrite <span class='op'>=</span> <span class='cn'>FALSE</span> -<span class='op'>)</span> - -<span class='co'># S3 method for mkinmod</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>x</span>, <span class='va'>...</span><span class='op'>)</span> - -<span class='fu'>mkinsub</span><span class='op'>(</span><span class='va'>submodel</span>, to <span class='op'>=</span> <span class='cn'>NULL</span>, sink <span class='op'>=</span> <span class='cn'>TRUE</span>, full_name <span class='op'>=</span> <span class='cn'>NA</span><span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">mkinmod</span><span class="op">(</span> + <span class="va">...</span>, + use_of_ff <span class="op">=</span> <span class="st">"max"</span>, + name <span class="op">=</span> <span class="cn">NULL</span>, + speclist <span class="op">=</span> <span class="cn">NULL</span>, + quiet <span class="op">=</span> <span class="cn">FALSE</span>, + verbose <span class="op">=</span> <span class="cn">FALSE</span>, + dll_dir <span class="op">=</span> <span class="cn">NULL</span>, + unload <span class="op">=</span> <span class="cn">FALSE</span>, + overwrite <span class="op">=</span> <span class="cn">FALSE</span> +<span class="op">)</span> + +<span class="co"># S3 method for mkinmod</span> +<span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">x</span>, <span class="va">...</span><span class="op">)</span> + +<span class="fu">mkinsub</span><span class="op">(</span><span class="va">submodel</span>, to <span class="op">=</span> <span class="cn">NULL</span>, sink <span class="op">=</span> <span class="cn">TRUE</span>, full_name <span class="op">=</span> <span class="cn">NA</span><span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>...</th> - <td><p>For each observed variable, a list as obtained by <code>mkinsub()</code> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>...</dt> +<dd><p>For each observed variable, a list as obtained by <code>mkinsub()</code> has to be specified as an argument (see examples). Currently, single first order kinetics "SFO", indeterminate order rate equation kinetics "IORE", or single first order with reversible binding "SFORB" are @@ -194,249 +129,234 @@ If the argument <code>use_of_ff</code> is set to "min" (default) and the model for the compartment is "SFO" or "SFORB", an additional <code>mkinsub()</code> argument can be <code>sink = FALSE</code>, effectively fixing the flux to sink to zero. -In print.mkinmod, this argument is currently not used.</p></td> - </tr> - <tr> - <th>use_of_ff</th> - <td><p>Specification of the use of formation fractions in the +In print.mkinmod, this argument is currently not used.</p></dd> +<dt>use_of_ff</dt> +<dd><p>Specification of the use of formation fractions in the model equations and, if applicable, the coefficient matrix. If "max", formation fractions are always used (default). If "min", a minimum use of formation fractions is made, i.e. each first-order pathway to a metabolite -has its own rate constant.</p></td> - </tr> - <tr> - <th>name</th> - <td><p>A name for the model. Should be a valid R object name.</p></td> - </tr> - <tr> - <th>speclist</th> - <td><p>The specification of the observed variables and their +has its own rate constant.</p></dd> +<dt>name</dt> +<dd><p>A name for the model. Should be a valid R object name.</p></dd> +<dt>speclist</dt> +<dd><p>The specification of the observed variables and their submodel types and pathways can be given as a single list using this -argument. Default is NULL.</p></td> - </tr> - <tr> - <th>quiet</th> - <td><p>Should messages be suppressed?</p></td> - </tr> - <tr> - <th>verbose</th> - <td><p>If <code>TRUE</code>, passed to <code><a href='https://rdrr.io/pkg/inline/man/cfunction.html'>inline::cfunction()</a></code> if -applicable to give detailed information about the C function being built.</p></td> - </tr> - <tr> - <th>dll_dir</th> - <td><p>Directory where an DLL object, if generated internally by -<code><a href='https://rdrr.io/pkg/inline/man/cfunction.html'>inline::cfunction()</a></code>, should be saved. The DLL will only be stored in a +argument. Default is NULL.</p></dd> +<dt>quiet</dt> +<dd><p>Should messages be suppressed?</p></dd> +<dt>verbose</dt> +<dd><p>If <code>TRUE</code>, passed to <code><a href="https://rdrr.io/pkg/inline/man/cfunction.html" class="external-link">inline::cfunction()</a></code> if +applicable to give detailed information about the C function being built.</p></dd> +<dt>dll_dir</dt> +<dd><p>Directory where an DLL object, if generated internally by +<code><a href="https://rdrr.io/pkg/inline/man/cfunction.html" class="external-link">inline::cfunction()</a></code>, should be saved. The DLL will only be stored in a permanent location for use in future sessions, if 'dll_dir' and 'name' -are specified.</p></td> - </tr> - <tr> - <th>unload</th> - <td><p>If a DLL from the target location in 'dll_dir' is already -loaded, should that be unloaded first?</p></td> - </tr> - <tr> - <th>overwrite</th> - <td><p>If a file exists at the target DLL location in 'dll_dir', -should this be overwritten?</p></td> - </tr> - <tr> - <th>x</th> - <td><p>An <code>mkinmod</code> object.</p></td> - </tr> - <tr> - <th>submodel</th> - <td><p>Character vector of length one to specify the submodel type. -See <code>mkinmod</code> for the list of allowed submodel names.</p></td> - </tr> - <tr> - <th>to</th> - <td><p>Vector of the names of the state variable to which a -transformation shall be included in the model.</p></td> - </tr> - <tr> - <th>sink</th> - <td><p>Should a pathway to sink be included in the model in addition to -the pathways to other state variables?</p></td> - </tr> - <tr> - <th>full_name</th> - <td><p>An optional name to be used e.g. for plotting fits +are specified.</p></dd> +<dt>unload</dt> +<dd><p>If a DLL from the target location in 'dll_dir' is already +loaded, should that be unloaded first?</p></dd> +<dt>overwrite</dt> +<dd><p>If a file exists at the target DLL location in 'dll_dir', +should this be overwritten?</p></dd> +<dt>x</dt> +<dd><p>An <code>mkinmod</code> object.</p></dd> +<dt>submodel</dt> +<dd><p>Character vector of length one to specify the submodel type. +See <code>mkinmod</code> for the list of allowed submodel names.</p></dd> +<dt>to</dt> +<dd><p>Vector of the names of the state variable to which a +transformation shall be included in the model.</p></dd> +<dt>sink</dt> +<dd><p>Should a pathway to sink be included in the model in addition to +the pathways to other state variables?</p></dd> +<dt>full_name</dt> +<dd><p>An optional name to be used e.g. for plotting fits performed with the model. You can use non-ASCII characters here, but then your R code will not be portable, <em>i.e.</em> may produce unintended plot -results on other operating systems or system configurations.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - - <p>A list of class <code>mkinmod</code> for use with <code><a href='mkinfit.html'>mkinfit()</a></code>, +results on other operating systems or system configurations.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>A list of class <code>mkinmod</code> for use with <code><a href="mkinfit.html">mkinfit()</a></code>, containing, among others,</p> -<dt>diffs</dt><dd><p>A vector of string representations of differential equations, one for +<dl><dt>diffs</dt> +<dd><p>A vector of string representations of differential equations, one for each modelling variable.</p></dd> -<dt>map</dt><dd><p>A list containing named character vectors for each observed variable, +<dt>map</dt> +<dd><p>A list containing named character vectors for each observed variable, specifying the modelling variables by which it is represented.</p></dd> -<dt>use_of_ff</dt><dd><p>The content of <code>use_of_ff</code> is passed on in this list component.</p></dd> -<dt>deg_func</dt><dd><p>If generated, a function containing the solution of the degradation +<dt>use_of_ff</dt> +<dd><p>The content of <code>use_of_ff</code> is passed on in this list component.</p></dd> +<dt>deg_func</dt> +<dd><p>If generated, a function containing the solution of the degradation model.</p></dd> -<dt>coefmat</dt><dd><p>The coefficient matrix, if the system of differential equations can be +<dt>coefmat</dt> +<dd><p>The coefficient matrix, if the system of differential equations can be represented by one.</p></dd> -<dt>cf</dt><dd><p>If generated, a compiled function calculating the derivatives as +<dt>cf</dt> +<dd><p>If generated, a compiled function calculating the derivatives as returned by cfunction.</p></dd> - -A list for use with mkinmod. - - <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2> - +</dl><p>A list for use with <code>mkinmod</code>.</p> + </div> + <div id="details"> + <h2>Details</h2> <p>For the definition of model types and their parameters, the equations given in the FOCUS and NAFTA guidance documents are used.</p> <p>For kinetic models with more than one observed variable, a symbolic solution of the system of differential equations is included in the resulting mkinmod object in some cases, speeding up the solution.</p> -<p>If a C compiler is found by <code><a href='https://rdrr.io/pkg/pkgbuild/man/has_compiler.html'>pkgbuild::has_compiler()</a></code> and there +<p>If a C compiler is found by <code><a href="https://rdrr.io/pkg/pkgbuild/man/has_compiler.html" class="external-link">pkgbuild::has_compiler()</a></code> and there is more than one observed variable in the specification, C code is generated for evaluating the differential equations, compiled using -<code><a href='https://rdrr.io/pkg/inline/man/cfunction.html'>inline::cfunction()</a></code> and added to the resulting mkinmod object.</p> - <h2 class="hasAnchor" id="note"><a class="anchor" href="#note"></a>Note</h2> - +<code><a href="https://rdrr.io/pkg/inline/man/cfunction.html" class="external-link">inline::cfunction()</a></code> and added to the resulting mkinmod object.</p> + </div> + <div id="note"> + <h2>Note</h2> <p>The IORE submodel is not well tested for metabolites. When using this model for metabolites, you may want to read the note in the help -page to <a href='mkinfit.html'>mkinfit</a>.</p> - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - - <p>FOCUS (2006) “Guidance Document on Estimating Persistence +page to <a href="mkinfit.html">mkinfit</a>.</p> + </div> + <div id="references"> + <h2>References</h2> + <p>FOCUS (2006) “Guidance Document on Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC Document Reference Sanco/10058/2005 version 2.0, 434 pp, -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> <p>NAFTA Technical Working Group on Pesticides (not dated) Guidance for Evaluating and Calculating Degradation Kinetics in Environmental Media</p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='co'># Specify the SFO model (this is not needed any more, as we can now mkinfit("SFO", ...)</span> -<span class='va'>SFO</span> <span class='op'><-</span> <span class='fu'>mkinmod</span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'>mkinsub</span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span> - -<span class='co'># One parent compound, one metabolite, both single first order</span> -<span class='va'>SFO_SFO</span> <span class='op'><-</span> <span class='fu'>mkinmod</span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'>mkinsub</span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"m1"</span><span class='op'>)</span>, - m1 <span class='op'>=</span> <span class='fu'>mkinsub</span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>SFO_SFO</span><span class='op'>)</span> -</div><div class='output co'>#> <mkinmod> model generated with -#> Use of formation fractions $use_of_ff: max -#> Specification $spec: -#> $parent -#> $type: SFO; $to: m1; $sink: TRUE -#> $m1 -#> $type: SFO; $sink: TRUE -#> Coefficient matrix $coefmat available -#> Compiled model $cf available -#> Differential equations: -#> d_parent/dt = - k_parent * parent -#> d_m1/dt = + f_parent_to_m1 * k_parent * parent - k_m1 * m1</div><div class='input'> -<span class='co'># \dontrun{</span> - <span class='va'>fit_sfo_sfo</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_2006_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, solution_type <span class='op'>=</span> <span class='st'>"deSolve"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='warning'>Warning: Observations with value of zero were removed from the data</span></div><div class='input'> - <span class='co'># Now supplying compound names used for plotting, and write to user defined location</span> - <span class='co'># We need to choose a path outside the session tempdir because this gets removed</span> - <span class='va'>DLL_dir</span> <span class='op'><-</span> <span class='st'>"~/.local/share/mkin"</span> - <span class='kw'>if</span> <span class='op'>(</span><span class='op'>!</span><span class='fu'><a href='https://rdrr.io/r/base/files2.html'>dir.exists</a></span><span class='op'>(</span><span class='va'>DLL_dir</span><span class='op'>)</span><span class='op'>)</span> <span class='fu'><a href='https://rdrr.io/r/base/files2.html'>dir.create</a></span><span class='op'>(</span><span class='va'>DLL_dir</span><span class='op'>)</span> - <span class='va'>SFO_SFO.2</span> <span class='op'><-</span> <span class='fu'>mkinmod</span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'>mkinsub</span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"m1"</span>, full_name <span class='op'>=</span> <span class='st'>"Test compound"</span><span class='op'>)</span>, - m1 <span class='op'>=</span> <span class='fu'>mkinsub</span><span class='op'>(</span><span class='st'>"SFO"</span>, full_name <span class='op'>=</span> <span class='st'>"Metabolite M1"</span><span class='op'>)</span>, - name <span class='op'>=</span> <span class='st'>"SFO_SFO"</span>, dll_dir <span class='op'>=</span> <span class='va'>DLL_dir</span>, unload <span class='op'>=</span> <span class='cn'>TRUE</span>, overwrite <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Copied DLL from /tmp/Rtmp1acwPp/fileb9e34769fb8fe.so to /home/jranke/.local/share/mkin/SFO_SFO.so</span></div><div class='input'><span class='co'># Now we can save the model and restore it in a new session</span> -<span class='fu'><a href='https://rdrr.io/r/base/readRDS.html'>saveRDS</a></span><span class='op'>(</span><span class='va'>SFO_SFO.2</span>, file <span class='op'>=</span> <span class='st'>"~/SFO_SFO.rds"</span><span class='op'>)</span> -<span class='co'># Terminate the R session here if you would like to check, and then do</span> -<span class='kw'><a href='https://rdrr.io/r/base/library.html'>library</a></span><span class='op'>(</span><span class='va'><a href='https://pkgdown.jrwb.de/mkin/'>mkin</a></span><span class='op'>)</span> -<span class='va'>SFO_SFO.3</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/readRDS.html'>readRDS</a></span><span class='op'>(</span><span class='st'>"~/SFO_SFO.rds"</span><span class='op'>)</span> -<span class='va'>fit_sfo_sfo</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO.3</span>, <span class='va'>FOCUS_2006_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, solution_type <span class='op'>=</span> <span class='st'>"deSolve"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='warning'>Warning: Observations with value of zero were removed from the data</span></div><div class='input'> -<span class='co'># Show details of creating the C function</span> -<span class='va'>SFO_SFO</span> <span class='op'><-</span> <span class='fu'>mkinmod</span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'>mkinsub</span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"m1"</span><span class='op'>)</span>, - m1 <span class='op'>=</span> <span class='fu'>mkinsub</span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, verbose <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> Program source: -#> 1: #include <R.h> -#> 2: -#> 3: -#> 4: static double parms [3]; -#> 5: #define k_parent parms[0] -#> 6: #define f_parent_to_m1 parms[1] -#> 7: #define k_m1 parms[2] -#> 8: -#> 9: void initpar(void (* odeparms)(int *, double *)) { -#> 10: int N = 3; -#> 11: odeparms(&N, parms); -#> 12: } -#> 13: -#> 14: -#> 15: void diffs ( int * n, double * t, double * y, double * f, double * rpar, int * ipar ) { -#> 16: -#> 17: f[0] = - k_parent * y[0]; -#> 18: f[1] = + f_parent_to_m1 * k_parent * y[0] - k_m1 * y[1]; -#> 19: }</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> -<span class='co'># The symbolic solution which is available in this case is not</span> -<span class='co'># made for human reading but for speed of computation</span> -<span class='va'>SFO_SFO</span><span class='op'>$</span><span class='va'>deg_func</span> -</div><div class='output co'>#> function (observed, odeini, odeparms) -#> { -#> predicted <- numeric(0) -#> with(as.list(odeparms), { -#> t <- observed[observed$name == "parent", "time"] -#> predicted <<- c(predicted, SFO.solution(t, odeini["parent"], -#> k_parent)) -#> t <- observed[observed$name == "m1", "time"] -#> predicted <<- c(predicted, (((k_m1 - k_parent) * odeini["m1"] - -#> f_parent_to_m1 * k_parent * odeini["parent"]) * exp(-k_m1 * -#> t) + f_parent_to_m1 * k_parent * odeini["parent"] * -#> exp(-k_parent * t))/(k_m1 - k_parent)) -#> }) -#> return(predicted) -#> } -#> <environment: 0x55555a720040></div><div class='input'> -<span class='co'># If we have several parallel metabolites</span> -<span class='co'># (compare tests/testthat/test_synthetic_data_for_UBA_2014.R)</span> -<span class='va'>m_synth_DFOP_par</span> <span class='op'><-</span> <span class='fu'>mkinmod</span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'>mkinsub</span><span class='op'>(</span><span class='st'>"DFOP"</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"M1"</span>, <span class='st'>"M2"</span><span class='op'>)</span><span class='op'>)</span>, - M1 <span class='op'>=</span> <span class='fu'>mkinsub</span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, - M2 <span class='op'>=</span> <span class='fu'>mkinsub</span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, - quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - -<span class='va'>fit_DFOP_par_c</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>m_synth_DFOP_par</span>, - <span class='va'>synthetic_data_for_UBA_2014</span><span class='op'>[[</span><span class='fl'>12</span><span class='op'>]</span><span class='op'>]</span><span class='op'>$</span><span class='va'>data</span>, - quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='co'># }</span> - -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="co"># Specify the SFO model (this is not needed any more, as we can now mkinfit("SFO", ...)</span></span> +<span class="r-in"><span class="va">SFO</span> <span class="op"><-</span> <span class="fu">mkinmod</span><span class="op">(</span>parent <span class="op">=</span> <span class="fu">mkinsub</span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># One parent compound, one metabolite, both single first order</span></span> +<span class="r-in"><span class="va">SFO_SFO</span> <span class="op"><-</span> <span class="fu">mkinmod</span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu">mkinsub</span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"m1"</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu">mkinsub</span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">SFO_SFO</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> <mkinmod> model generated with</span> +<span class="r-out co"><span class="r-pr">#></span> Use of formation fractions $use_of_ff: max </span> +<span class="r-out co"><span class="r-pr">#></span> Specification $spec:</span> +<span class="r-out co"><span class="r-pr">#></span> $parent</span> +<span class="r-out co"><span class="r-pr">#></span> $type: SFO; $to: m1; $sink: TRUE</span> +<span class="r-out co"><span class="r-pr">#></span> $m1</span> +<span class="r-out co"><span class="r-pr">#></span> $type: SFO; $sink: TRUE</span> +<span class="r-out co"><span class="r-pr">#></span> Coefficient matrix $coefmat available</span> +<span class="r-out co"><span class="r-pr">#></span> Compiled model $cf available</span> +<span class="r-out co"><span class="r-pr">#></span> Differential equations:</span> +<span class="r-out co"><span class="r-pr">#></span> d_parent/dt = - k_parent * parent</span> +<span class="r-out co"><span class="r-pr">#></span> d_m1/dt = + f_parent_to_m1 * k_parent * parent - k_m1 * m1</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"> <span class="va">fit_sfo_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_2006_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, solution_type <span class="op">=</span> <span class="st">"deSolve"</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"> <span class="co"># Now supplying compound names used for plotting, and write to user defined location</span></span> +<span class="r-in"> <span class="co"># We need to choose a path outside the session tempdir because this gets removed</span></span> +<span class="r-in"> <span class="va">DLL_dir</span> <span class="op"><-</span> <span class="st">"~/.local/share/mkin"</span></span> +<span class="r-in"> <span class="kw">if</span> <span class="op">(</span><span class="op">!</span><span class="fu"><a href="https://rdrr.io/r/base/files2.html" class="external-link">dir.exists</a></span><span class="op">(</span><span class="va">DLL_dir</span><span class="op">)</span><span class="op">)</span> <span class="fu"><a href="https://rdrr.io/r/base/files2.html" class="external-link">dir.create</a></span><span class="op">(</span><span class="va">DLL_dir</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">SFO_SFO.2</span> <span class="op"><-</span> <span class="fu">mkinmod</span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu">mkinsub</span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"m1"</span>, full_name <span class="op">=</span> <span class="st">"Test compound"</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu">mkinsub</span><span class="op">(</span><span class="st">"SFO"</span>, full_name <span class="op">=</span> <span class="st">"Metabolite M1"</span><span class="op">)</span>,</span> +<span class="r-in"> name <span class="op">=</span> <span class="st">"SFO_SFO"</span>, dll_dir <span class="op">=</span> <span class="va">DLL_dir</span>, unload <span class="op">=</span> <span class="cn">TRUE</span>, overwrite <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Copied DLL from /tmp/RtmpNObdrK/filecabc85d9446.so to /home/jranke/.local/share/mkin/SFO_SFO.so</span> +<span class="r-in"><span class="co"># Now we can save the model and restore it in a new session</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/readRDS.html" class="external-link">saveRDS</a></span><span class="op">(</span><span class="va">SFO_SFO.2</span>, file <span class="op">=</span> <span class="st">"~/SFO_SFO.rds"</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># Terminate the R session here if you would like to check, and then do</span></span> +<span class="r-in"><span class="kw"><a href="https://rdrr.io/r/base/library.html" class="external-link">library</a></span><span class="op">(</span><span class="va"><a href="https://pkgdown.jrwb.de/mkin/">mkin</a></span><span class="op">)</span></span> +<span class="r-in"><span class="va">SFO_SFO.3</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/readRDS.html" class="external-link">readRDS</a></span><span class="op">(</span><span class="st">"~/SFO_SFO.rds"</span><span class="op">)</span></span> +<span class="r-in"><span class="va">fit_sfo_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO.3</span>, <span class="va">FOCUS_2006_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, solution_type <span class="op">=</span> <span class="st">"deSolve"</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Show details of creating the C function</span></span> +<span class="r-in"><span class="va">SFO_SFO</span> <span class="op"><-</span> <span class="fu">mkinmod</span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu">mkinsub</span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"m1"</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu">mkinsub</span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>, verbose <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Program source:</span> +<span class="r-out co"><span class="r-pr">#></span> 1: #include <R.h></span> +<span class="r-out co"><span class="r-pr">#></span> 2: </span> +<span class="r-out co"><span class="r-pr">#></span> 3: </span> +<span class="r-out co"><span class="r-pr">#></span> 4: static double parms [3];</span> +<span class="r-out co"><span class="r-pr">#></span> 5: #define k_parent parms[0]</span> +<span class="r-out co"><span class="r-pr">#></span> 6: #define f_parent_to_m1 parms[1]</span> +<span class="r-out co"><span class="r-pr">#></span> 7: #define k_m1 parms[2]</span> +<span class="r-out co"><span class="r-pr">#></span> 8: </span> +<span class="r-out co"><span class="r-pr">#></span> 9: void initpar(void (* odeparms)(int *, double *)) {</span> +<span class="r-out co"><span class="r-pr">#></span> 10: int N = 3;</span> +<span class="r-out co"><span class="r-pr">#></span> 11: odeparms(&N, parms);</span> +<span class="r-out co"><span class="r-pr">#></span> 12: }</span> +<span class="r-out co"><span class="r-pr">#></span> 13: </span> +<span class="r-out co"><span class="r-pr">#></span> 14: </span> +<span class="r-out co"><span class="r-pr">#></span> 15: void diffs ( int * n, double * t, double * y, double * f, double * rpar, int * ipar ) {</span> +<span class="r-out co"><span class="r-pr">#></span> 16: </span> +<span class="r-out co"><span class="r-pr">#></span> 17: f[0] = - k_parent * y[0];</span> +<span class="r-out co"><span class="r-pr">#></span> 18: f[1] = + f_parent_to_m1 * k_parent * y[0] - k_m1 * y[1];</span> +<span class="r-out co"><span class="r-pr">#></span> 19: }</span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># The symbolic solution which is available in this case is not</span></span> +<span class="r-in"><span class="co"># made for human reading but for speed of computation</span></span> +<span class="r-in"><span class="va">SFO_SFO</span><span class="op">$</span><span class="va">deg_func</span></span> +<span class="r-out co"><span class="r-pr">#></span> function (observed, odeini, odeparms) </span> +<span class="r-out co"><span class="r-pr">#></span> {</span> +<span class="r-out co"><span class="r-pr">#></span> predicted <- numeric(0)</span> +<span class="r-out co"><span class="r-pr">#></span> with(as.list(odeparms), {</span> +<span class="r-out co"><span class="r-pr">#></span> t <- observed[observed$name == "parent", "time"]</span> +<span class="r-out co"><span class="r-pr">#></span> predicted <<- c(predicted, SFO.solution(t, odeini["parent"], </span> +<span class="r-out co"><span class="r-pr">#></span> k_parent))</span> +<span class="r-out co"><span class="r-pr">#></span> t <- observed[observed$name == "m1", "time"]</span> +<span class="r-out co"><span class="r-pr">#></span> predicted <<- c(predicted, (((k_m1 - k_parent) * odeini["m1"] - </span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_m1 * k_parent * odeini["parent"]) * exp(-k_m1 * </span> +<span class="r-out co"><span class="r-pr">#></span> t) + f_parent_to_m1 * k_parent * odeini["parent"] * </span> +<span class="r-out co"><span class="r-pr">#></span> exp(-k_parent * t))/(k_m1 - k_parent))</span> +<span class="r-out co"><span class="r-pr">#></span> })</span> +<span class="r-out co"><span class="r-pr">#></span> return(predicted)</span> +<span class="r-out co"><span class="r-pr">#></span> }</span> +<span class="r-out co"><span class="r-pr">#></span> <environment: 0x5555673b8fd0></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># If we have several parallel metabolites</span></span> +<span class="r-in"><span class="co"># (compare tests/testthat/test_synthetic_data_for_UBA_2014.R)</span></span> +<span class="r-in"><span class="va">m_synth_DFOP_par</span> <span class="op"><-</span> <span class="fu">mkinmod</span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu">mkinsub</span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"M1"</span>, <span class="st">"M2"</span><span class="op">)</span><span class="op">)</span>,</span> +<span class="r-in"> M1 <span class="op">=</span> <span class="fu">mkinsub</span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> M2 <span class="op">=</span> <span class="fu">mkinsub</span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">fit_DFOP_par_c</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">m_synth_DFOP_par</span>,</span> +<span class="r-in"> <span class="va">synthetic_data_for_UBA_2014</span><span class="op">[[</span><span class="fl">12</span><span class="op">]</span><span class="op">]</span><span class="op">$</span><span class="va">data</span>,</span> +<span class="r-in"> quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># }</span></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/mkinparplot-1.png b/docs/reference/mkinparplot-1.png Binary files differindex c9ed49eb..fff98391 100644 --- a/docs/reference/mkinparplot-1.png +++ b/docs/reference/mkinparplot-1.png diff --git a/docs/reference/mkinparplot.html b/docs/reference/mkinparplot.html index c298f5d2..2d7f6228 100644 --- a/docs/reference/mkinparplot.html +++ b/docs/reference/mkinparplot.html @@ -1,68 +1,13 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Function to plot the confidence intervals obtained using mkinfit — mkinparplot • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Function to plot the confidence intervals obtained using mkinfit — mkinparplot" /> -<meta property="og:description" content="This function plots the confidence intervals for the parameters fitted using -mkinfit." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Function to plot the confidence intervals obtained using mkinfit — mkinparplot • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Function to plot the confidence intervals obtained using mkinfit — mkinparplot"><meta property="og:description" content="This function plots the confidence intervals for the parameters fitted using +mkinfit."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -73,13 +18,12 @@ mkinfit." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -88,8 +32,7 @@ mkinfit." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -99,6 +42,9 @@ mkinfit." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -113,98 +59,90 @@ mkinfit." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Function to plot the confidence intervals obtained using mkinfit</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/mkinparplot.R'><code>R/mkinparplot.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/mkinparplot.R" class="external-link"><code>R/mkinparplot.R</code></a></small> <div class="hidden name"><code>mkinparplot.Rd</code></div> </div> <div class="ref-description"> <p>This function plots the confidence intervals for the parameters fitted using -<code><a href='mkinfit.html'>mkinfit</a></code>.</p> +<code><a href="mkinfit.html">mkinfit</a></code>.</p> </div> - <pre class="usage"><span class='fu'>mkinparplot</span><span class='op'>(</span><span class='va'>object</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>A fit represented in an <code><a href='mkinfit.html'>mkinfit</a></code> object.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">mkinparplot</span><span class="op">(</span><span class="va">object</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>A fit represented in an <code><a href="mkinfit.html">mkinfit</a></code> object.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>Nothing is returned by this function, as it is called for its side effect, namely to produce a plot.</p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='co'># \dontrun{</span> -<span class='va'>model</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span> - T245 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"phenol"</span><span class='op'>)</span>, sink <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span>, - phenol <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"anisole"</span><span class='op'>)</span><span class='op'>)</span>, - anisole <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'><span class='va'>fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>model</span>, <span class='fu'><a href='https://rdrr.io/r/base/subset.html'>subset</a></span><span class='op'>(</span><span class='va'>mccall81_245T</span>, <span class='va'>soil</span> <span class='op'>==</span> <span class='st'>"Commerce"</span><span class='op'>)</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='warning'>Warning: Observations with value of zero were removed from the data</span></div><div class='output co'>#> <span class='warning'>Warning: Optimisation did not converge:</span> -#> <span class='warning'>false convergence (8)</span></div><div class='input'><span class='fu'>mkinparplot</span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span> -</div><div class='img'><img src='mkinparplot-1.png' alt='' width='700' height='433' /></div><div class='input'><span class='co'># }</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="va">model</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> T245 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, to <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"phenol"</span><span class="op">)</span>, sink <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span>,</span> +<span class="r-in"> phenol <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, to <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"anisole"</span><span class="op">)</span><span class="op">)</span>,</span> +<span class="r-in"> anisole <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>, use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="va">fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">model</span>, <span class="fu"><a href="https://rdrr.io/r/base/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">mccall81_245T</span>, <span class="va">soil</span> <span class="op">==</span> <span class="st">"Commerce"</span><span class="op">)</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu">mkinparplot</span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></span> +<span class="r-plt img"><img src="mkinparplot-1.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/mkinplot.html b/docs/reference/mkinplot.html index b20a8c96..896c30a0 100644 --- a/docs/reference/mkinplot.html +++ b/docs/reference/mkinplot.html @@ -1,68 +1,13 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Plot the observed data and the fitted model of an mkinfit object — mkinplot • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Plot the observed data and the fitted model of an mkinfit object — mkinplot" /> -<meta property="og:description" content="Deprecated function. It now only calls the plot method -plot.mkinfit." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Plot the observed data and the fitted model of an mkinfit object — mkinplot • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Plot the observed data and the fitted model of an mkinfit object — mkinplot"><meta property="og:description" content="Deprecated function. It now only calls the plot method +plot.mkinfit."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -73,13 +18,12 @@ plot.mkinfit." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -88,8 +32,7 @@ plot.mkinfit." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -99,6 +42,9 @@ plot.mkinfit." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -113,89 +59,76 @@ plot.mkinfit." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Plot the observed data and the fitted model of an mkinfit object</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/plot.mkinfit.R'><code>R/plot.mkinfit.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/plot.mkinfit.R" class="external-link"><code>R/plot.mkinfit.R</code></a></small> <div class="hidden name"><code>mkinplot.Rd</code></div> </div> <div class="ref-description"> <p>Deprecated function. It now only calls the plot method -<code><a href='plot.mkinfit.html'>plot.mkinfit</a></code>.</p> +<code><a href="plot.mkinfit.html">plot.mkinfit</a></code>.</p> </div> - <pre class="usage"><span class='fu'>mkinplot</span><span class='op'>(</span><span class='va'>fit</span>, <span class='va'>...</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>fit</th> - <td><p>an object of class <code><a href='mkinfit.html'>mkinfit</a></code>.</p></td> - </tr> - <tr> - <th>...</th> - <td><p>further arguments passed to <code><a href='plot.mkinfit.html'>plot.mkinfit</a></code>.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">mkinplot</span><span class="op">(</span><span class="va">fit</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>fit</dt> +<dd><p>an object of class <code><a href="mkinfit.html">mkinfit</a></code>.</p></dd> +<dt>...</dt> +<dd><p>further arguments passed to <code><a href="plot.mkinfit.html">plot.mkinfit</a></code>.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The function is called for its side effect.</p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/mkinpredict.html b/docs/reference/mkinpredict.html index 5775ba62..b52d9ece 100644 --- a/docs/reference/mkinpredict.html +++ b/docs/reference/mkinpredict.html @@ -1,69 +1,14 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Produce predictions from a kinetic model using specific parameters — mkinpredict • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Produce predictions from a kinetic model using specific parameters — mkinpredict" /> -<meta property="og:description" content="This function produces a time series for all the observed variables in a +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Produce predictions from a kinetic model using specific parameters — mkinpredict • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Produce predictions from a kinetic model using specific parameters — mkinpredict"><meta property="og:description" content="This function produces a time series for all the observed variables in a kinetic model as specified by mkinmod, using a specific set of -kinetic parameters and initial values for the state variables." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +kinetic parameters and initial values for the state variables."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -74,13 +19,12 @@ kinetic parameters and initial values for the state variables." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -89,8 +33,7 @@ kinetic parameters and initial values for the state variables." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -100,6 +43,9 @@ kinetic parameters and initial values for the state variables." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -114,343 +60,325 @@ kinetic parameters and initial values for the state variables." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Produce predictions from a kinetic model using specific parameters</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/mkinpredict.R'><code>R/mkinpredict.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/mkinpredict.R" class="external-link"><code>R/mkinpredict.R</code></a></small> <div class="hidden name"><code>mkinpredict.Rd</code></div> </div> <div class="ref-description"> <p>This function produces a time series for all the observed variables in a -kinetic model as specified by <code><a href='mkinmod.html'>mkinmod</a></code>, using a specific set of +kinetic model as specified by <code><a href="mkinmod.html">mkinmod</a></code>, using a specific set of kinetic parameters and initial values for the state variables.</p> </div> - <pre class="usage"><span class='fu'>mkinpredict</span><span class='op'>(</span><span class='va'>x</span>, <span class='va'>odeparms</span>, <span class='va'>odeini</span>, <span class='va'>outtimes</span>, <span class='va'>...</span><span class='op'>)</span> - -<span class='co'># S3 method for mkinmod</span> -<span class='fu'>mkinpredict</span><span class='op'>(</span> - <span class='va'>x</span>, - odeparms <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_parent_sink <span class='op'>=</span> <span class='fl'>0.1</span><span class='op'>)</span>, - odeini <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>100</span><span class='op'>)</span>, - outtimes <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/seq.html'>seq</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>120</span>, by <span class='op'>=</span> <span class='fl'>0.1</span><span class='op'>)</span>, - solution_type <span class='op'>=</span> <span class='st'>"deSolve"</span>, - use_compiled <span class='op'>=</span> <span class='st'>"auto"</span>, - method.ode <span class='op'>=</span> <span class='st'>"lsoda"</span>, - atol <span class='op'>=</span> <span class='fl'>1e-08</span>, - rtol <span class='op'>=</span> <span class='fl'>1e-10</span>, - map_output <span class='op'>=</span> <span class='cn'>TRUE</span>, - na_stop <span class='op'>=</span> <span class='cn'>TRUE</span>, - <span class='va'>...</span> -<span class='op'>)</span> - -<span class='co'># S3 method for mkinfit</span> -<span class='fu'>mkinpredict</span><span class='op'>(</span> - <span class='va'>x</span>, - odeparms <span class='op'>=</span> <span class='va'>x</span><span class='op'>$</span><span class='va'>bparms.ode</span>, - odeini <span class='op'>=</span> <span class='va'>x</span><span class='op'>$</span><span class='va'>bparms.state</span>, - outtimes <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/seq.html'>seq</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>120</span>, by <span class='op'>=</span> <span class='fl'>0.1</span><span class='op'>)</span>, - solution_type <span class='op'>=</span> <span class='st'>"deSolve"</span>, - use_compiled <span class='op'>=</span> <span class='st'>"auto"</span>, - method.ode <span class='op'>=</span> <span class='st'>"lsoda"</span>, - atol <span class='op'>=</span> <span class='fl'>1e-08</span>, - rtol <span class='op'>=</span> <span class='fl'>1e-10</span>, - map_output <span class='op'>=</span> <span class='cn'>TRUE</span>, - <span class='va'>...</span> -<span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">mkinpredict</span><span class="op">(</span><span class="va">x</span>, <span class="va">odeparms</span>, <span class="va">odeini</span>, <span class="va">outtimes</span>, <span class="va">...</span><span class="op">)</span> + +<span class="co"># S3 method for mkinmod</span> +<span class="fu">mkinpredict</span><span class="op">(</span> + <span class="va">x</span>, + odeparms <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_parent_sink <span class="op">=</span> <span class="fl">0.1</span><span class="op">)</span>, + odeini <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span><span class="op">)</span>, + outtimes <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/seq.html" class="external-link">seq</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">120</span>, by <span class="op">=</span> <span class="fl">0.1</span><span class="op">)</span>, + solution_type <span class="op">=</span> <span class="st">"deSolve"</span>, + use_compiled <span class="op">=</span> <span class="st">"auto"</span>, + method.ode <span class="op">=</span> <span class="st">"lsoda"</span>, + atol <span class="op">=</span> <span class="fl">1e-08</span>, + rtol <span class="op">=</span> <span class="fl">1e-10</span>, + map_output <span class="op">=</span> <span class="cn">TRUE</span>, + na_stop <span class="op">=</span> <span class="cn">TRUE</span>, + <span class="va">...</span> +<span class="op">)</span> + +<span class="co"># S3 method for mkinfit</span> +<span class="fu">mkinpredict</span><span class="op">(</span> + <span class="va">x</span>, + odeparms <span class="op">=</span> <span class="va">x</span><span class="op">$</span><span class="va">bparms.ode</span>, + odeini <span class="op">=</span> <span class="va">x</span><span class="op">$</span><span class="va">bparms.state</span>, + outtimes <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/seq.html" class="external-link">seq</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">120</span>, by <span class="op">=</span> <span class="fl">0.1</span><span class="op">)</span>, + solution_type <span class="op">=</span> <span class="st">"deSolve"</span>, + use_compiled <span class="op">=</span> <span class="st">"auto"</span>, + method.ode <span class="op">=</span> <span class="st">"lsoda"</span>, + atol <span class="op">=</span> <span class="fl">1e-08</span>, + rtol <span class="op">=</span> <span class="fl">1e-10</span>, + map_output <span class="op">=</span> <span class="cn">TRUE</span>, + <span class="va">...</span> +<span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>x</th> - <td><p>A kinetic model as produced by <code><a href='mkinmod.html'>mkinmod</a></code>, or a kinetic -fit as fitted by <code><a href='mkinfit.html'>mkinfit</a></code>. In the latter case, the fitted -parameters are used for the prediction.</p></td> - </tr> - <tr> - <th>odeparms</th> - <td><p>A numeric vector specifying the parameters used in the + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>x</dt> +<dd><p>A kinetic model as produced by <code><a href="mkinmod.html">mkinmod</a></code>, or a kinetic +fit as fitted by <code><a href="mkinfit.html">mkinfit</a></code>. In the latter case, the fitted +parameters are used for the prediction.</p></dd> +<dt>odeparms</dt> +<dd><p>A numeric vector specifying the parameters used in the kinetic model, which is generally defined as a set of ordinary -differential equations.</p></td> - </tr> - <tr> - <th>odeini</th> - <td><p>A numeric vector containing the initial values of the state +differential equations.</p></dd> +<dt>odeini</dt> +<dd><p>A numeric vector containing the initial values of the state variables of the model. Note that the state variables can differ from the -observed variables, for example in the case of the SFORB model.</p></td> - </tr> - <tr> - <th>outtimes</th> - <td><p>A numeric vector specifying the time points for which model -predictions should be generated.</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Further arguments passed to the ode solver in case such a -solver is used.</p></td> - </tr> - <tr> - <th>solution_type</th> - <td><p>The method that should be used for producing the +observed variables, for example in the case of the SFORB model.</p></dd> +<dt>outtimes</dt> +<dd><p>A numeric vector specifying the time points for which model +predictions should be generated.</p></dd> +<dt>...</dt> +<dd><p>Further arguments passed to the ode solver in case such a +solver is used.</p></dd> +<dt>solution_type</dt> +<dd><p>The method that should be used for producing the predictions. This should generally be "analytical" if there is only one observed variable, and usually "deSolve" in the case of several observed variables. The third possibility "eigen" is faster but not applicable to -some models e.g. using FOMC for the parent compound.</p></td> - </tr> - <tr> - <th>use_compiled</th> - <td><p>If set to <code>FALSE</code>, no compiled version of the -<code><a href='mkinmod.html'>mkinmod</a></code> model is used, even if is present.</p></td> - </tr> - <tr> - <th>method.ode</th> - <td><p>The solution method passed via <code>mkinpredict</code> +some models e.g. using FOMC for the parent compound.</p></dd> +<dt>use_compiled</dt> +<dd><p>If set to <code>FALSE</code>, no compiled version of the +<code><a href="mkinmod.html">mkinmod</a></code> model is used, even if is present.</p></dd> +<dt>method.ode</dt> +<dd><p>The solution method passed via <code>mkinpredict</code> to <code>ode</code> in case the solution type is "deSolve". The default -"lsoda" is performant, but sometimes fails to converge.</p></td> - </tr> - <tr> - <th>atol</th> - <td><p>Absolute error tolerance, passed to <code>ode</code>. Default -is 1e-8, lower than in <code>lsoda</code>.</p></td> - </tr> - <tr> - <th>rtol</th> - <td><p>Absolute error tolerance, passed to <code>ode</code>. Default -is 1e-10, much lower than in <code>lsoda</code>.</p></td> - </tr> - <tr> - <th>map_output</th> - <td><p>Boolean to specify if the output should list values for +"lsoda" is performant, but sometimes fails to converge.</p></dd> +<dt>atol</dt> +<dd><p>Absolute error tolerance, passed to <code>ode</code>. Default +is 1e-8, lower than in <code>lsoda</code>.</p></dd> +<dt>rtol</dt> +<dd><p>Absolute error tolerance, passed to <code>ode</code>. Default +is 1e-10, much lower than in <code>lsoda</code>.</p></dd> +<dt>map_output</dt> +<dd><p>Boolean to specify if the output should list values for the observed variables (default) or for all state variables (if set to FALSE). Setting this to FALSE has no effect for analytical solutions, -as these always return mapped output.</p></td> - </tr> - <tr> - <th>na_stop</th> - <td><p>Should it be an error if deSolve::ode returns NaN values</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - +as these always return mapped output.</p></dd> +<dt>na_stop</dt> +<dd><p>Should it be an error if deSolve::ode returns NaN values</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>A matrix with the numeric solution in wide format</p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='va'>SFO</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>degradinol <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span> -<span class='co'># Compare solution types</span> -<span class='fu'>mkinpredict</span><span class='op'>(</span><span class='va'>SFO</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_degradinol <span class='op'>=</span> <span class='fl'>0.3</span><span class='op'>)</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>degradinol <span class='op'>=</span> <span class='fl'>100</span><span class='op'>)</span>, <span class='fl'>0</span><span class='op'>:</span><span class='fl'>20</span>, - solution_type <span class='op'>=</span> <span class='st'>"analytical"</span><span class='op'>)</span> -</div><div class='output co'>#> time degradinol -#> 0 0 100.0000000 -#> 1 1 74.0818221 -#> 2 2 54.8811636 -#> 3 3 40.6569660 -#> 4 4 30.1194212 -#> 5 5 22.3130160 -#> 6 6 16.5298888 -#> 7 7 12.2456428 -#> 8 8 9.0717953 -#> 9 9 6.7205513 -#> 10 10 4.9787068 -#> 11 11 3.6883167 -#> 12 12 2.7323722 -#> 13 13 2.0241911 -#> 14 14 1.4995577 -#> 15 15 1.1108997 -#> 16 16 0.8229747 -#> 17 17 0.6096747 -#> 18 18 0.4516581 -#> 19 19 0.3345965 -#> 20 20 0.2478752</div><div class='input'><span class='fu'>mkinpredict</span><span class='op'>(</span><span class='va'>SFO</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_degradinol <span class='op'>=</span> <span class='fl'>0.3</span><span class='op'>)</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>degradinol <span class='op'>=</span> <span class='fl'>100</span><span class='op'>)</span>, <span class='fl'>0</span><span class='op'>:</span><span class='fl'>20</span>, - solution_type <span class='op'>=</span> <span class='st'>"deSolve"</span><span class='op'>)</span> -</div><div class='output co'>#> time degradinol -#> 0 0 100.0000000 -#> 1 1 74.0818221 -#> 2 2 54.8811636 -#> 3 3 40.6569660 -#> 4 4 30.1194212 -#> 5 5 22.3130160 -#> 6 6 16.5298888 -#> 7 7 12.2456428 -#> 8 8 9.0717953 -#> 9 9 6.7205513 -#> 10 10 4.9787068 -#> 11 11 3.6883167 -#> 12 12 2.7323722 -#> 13 13 2.0241911 -#> 14 14 1.4995577 -#> 15 15 1.1108996 -#> 16 16 0.8229747 -#> 17 17 0.6096747 -#> 18 18 0.4516581 -#> 19 19 0.3345965 -#> 20 20 0.2478752</div><div class='input'><span class='fu'>mkinpredict</span><span class='op'>(</span><span class='va'>SFO</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_degradinol <span class='op'>=</span> <span class='fl'>0.3</span><span class='op'>)</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>degradinol <span class='op'>=</span> <span class='fl'>100</span><span class='op'>)</span>, <span class='fl'>0</span><span class='op'>:</span><span class='fl'>20</span>, - solution_type <span class='op'>=</span> <span class='st'>"deSolve"</span>, use_compiled <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span> -</div><div class='output co'>#> time degradinol -#> 0 0 100.0000000 -#> 1 1 74.0818221 -#> 2 2 54.8811636 -#> 3 3 40.6569660 -#> 4 4 30.1194212 -#> 5 5 22.3130160 -#> 6 6 16.5298888 -#> 7 7 12.2456428 -#> 8 8 9.0717953 -#> 9 9 6.7205513 -#> 10 10 4.9787068 -#> 11 11 3.6883167 -#> 12 12 2.7323722 -#> 13 13 2.0241911 -#> 14 14 1.4995577 -#> 15 15 1.1108996 -#> 16 16 0.8229747 -#> 17 17 0.6096747 -#> 18 18 0.4516581 -#> 19 19 0.3345965 -#> 20 20 0.2478752</div><div class='input'><span class='fu'>mkinpredict</span><span class='op'>(</span><span class='va'>SFO</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_degradinol <span class='op'>=</span> <span class='fl'>0.3</span><span class='op'>)</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>degradinol <span class='op'>=</span> <span class='fl'>100</span><span class='op'>)</span>, <span class='fl'>0</span><span class='op'>:</span><span class='fl'>20</span>, - solution_type <span class='op'>=</span> <span class='st'>"eigen"</span><span class='op'>)</span> -</div><div class='output co'>#> time degradinol -#> 0 0 100.0000000 -#> 1 1 74.0818221 -#> 2 2 54.8811636 -#> 3 3 40.6569660 -#> 4 4 30.1194212 -#> 5 5 22.3130160 -#> 6 6 16.5298888 -#> 7 7 12.2456428 -#> 8 8 9.0717953 -#> 9 9 6.7205513 -#> 10 10 4.9787068 -#> 11 11 3.6883167 -#> 12 12 2.7323722 -#> 13 13 2.0241911 -#> 14 14 1.4995577 -#> 15 15 1.1108997 -#> 16 16 0.8229747 -#> 17 17 0.6096747 -#> 18 18 0.4516581 -#> 19 19 0.3345965 -#> 20 20 0.2478752</div><div class='input'> -<span class='co'># Compare integration methods to analytical solution</span> -<span class='fu'>mkinpredict</span><span class='op'>(</span><span class='va'>SFO</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_degradinol <span class='op'>=</span> <span class='fl'>0.3</span><span class='op'>)</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>degradinol <span class='op'>=</span> <span class='fl'>100</span><span class='op'>)</span>, <span class='fl'>0</span><span class='op'>:</span><span class='fl'>20</span>, - solution_type <span class='op'>=</span> <span class='st'>"analytical"</span><span class='op'>)</span><span class='op'>[</span><span class='fl'>21</span>,<span class='op'>]</span> -</div><div class='output co'>#> time degradinol -#> 20.0000000 0.2478752 </div><div class='input'><span class='fu'>mkinpredict</span><span class='op'>(</span><span class='va'>SFO</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_degradinol <span class='op'>=</span> <span class='fl'>0.3</span><span class='op'>)</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>degradinol <span class='op'>=</span> <span class='fl'>100</span><span class='op'>)</span>, <span class='fl'>0</span><span class='op'>:</span><span class='fl'>20</span>, - method <span class='op'>=</span> <span class='st'>"lsoda"</span><span class='op'>)</span><span class='op'>[</span><span class='fl'>21</span>,<span class='op'>]</span> -</div><div class='output co'>#> time degradinol -#> 20.0000000 0.2478752 </div><div class='input'><span class='fu'>mkinpredict</span><span class='op'>(</span><span class='va'>SFO</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_degradinol <span class='op'>=</span> <span class='fl'>0.3</span><span class='op'>)</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>degradinol <span class='op'>=</span> <span class='fl'>100</span><span class='op'>)</span>, <span class='fl'>0</span><span class='op'>:</span><span class='fl'>20</span>, - method <span class='op'>=</span> <span class='st'>"ode45"</span><span class='op'>)</span><span class='op'>[</span><span class='fl'>21</span>,<span class='op'>]</span> -</div><div class='output co'>#> time degradinol -#> 20.0000000 0.2478752 </div><div class='input'><span class='fu'>mkinpredict</span><span class='op'>(</span><span class='va'>SFO</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_degradinol <span class='op'>=</span> <span class='fl'>0.3</span><span class='op'>)</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>degradinol <span class='op'>=</span> <span class='fl'>100</span><span class='op'>)</span>, <span class='fl'>0</span><span class='op'>:</span><span class='fl'>20</span>, - method <span class='op'>=</span> <span class='st'>"rk4"</span><span class='op'>)</span><span class='op'>[</span><span class='fl'>21</span>,<span class='op'>]</span> -</div><div class='output co'>#> time degradinol -#> 20.0000000 0.2480043 </div><div class='input'><span class='co'># rk4 is not as precise here</span> - -<span class='co'># The number of output times used to make a lot of difference until the</span> -<span class='co'># default for atol was adjusted</span> -<span class='fu'>mkinpredict</span><span class='op'>(</span><span class='va'>SFO</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_degradinol <span class='op'>=</span> <span class='fl'>0.3</span><span class='op'>)</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>degradinol <span class='op'>=</span> <span class='fl'>100</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/seq.html'>seq</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>20</span>, by <span class='op'>=</span> <span class='fl'>0.1</span><span class='op'>)</span><span class='op'>)</span><span class='op'>[</span><span class='fl'>201</span>,<span class='op'>]</span> -</div><div class='output co'>#> time degradinol -#> 20.0000000 0.2478752 </div><div class='input'><span class='fu'>mkinpredict</span><span class='op'>(</span><span class='va'>SFO</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_degradinol <span class='op'>=</span> <span class='fl'>0.3</span><span class='op'>)</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>degradinol <span class='op'>=</span> <span class='fl'>100</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/seq.html'>seq</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>20</span>, by <span class='op'>=</span> <span class='fl'>0.01</span><span class='op'>)</span><span class='op'>)</span><span class='op'>[</span><span class='fl'>2001</span>,<span class='op'>]</span> -</div><div class='output co'>#> time degradinol -#> 20.0000000 0.2478752 </div><div class='input'> -<span class='co'># Comparison of the performance of solution types</span> -<span class='va'>SFO_SFO</span> <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"m1"</span><span class='op'>)</span>, - m1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'><span class='kw'>if</span><span class='op'>(</span><span class='kw'><a href='https://rdrr.io/r/base/library.html'>require</a></span><span class='op'>(</span><span class='va'><a href='http://rbenchmark.googlecode.com'>rbenchmark</a></span><span class='op'>)</span><span class='op'>)</span> <span class='op'>{</span> - <span class='fu'><a href='https://rdrr.io/pkg/rbenchmark/man/benchmark.html'>benchmark</a></span><span class='op'>(</span>replications <span class='op'>=</span> <span class='fl'>10</span>, order <span class='op'>=</span> <span class='st'>"relative"</span>, columns <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"test"</span>, <span class='st'>"relative"</span>, <span class='st'>"elapsed"</span><span class='op'>)</span>, - eigen <span class='op'>=</span> <span class='fu'>mkinpredict</span><span class='op'>(</span><span class='va'>SFO_SFO</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_parent <span class='op'>=</span> <span class='fl'>0.15</span>, f_parent_to_m1 <span class='op'>=</span> <span class='fl'>0.5</span>, k_m1 <span class='op'>=</span> <span class='fl'>0.01</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>100</span>, m1 <span class='op'>=</span> <span class='fl'>0</span><span class='op'>)</span>, <span class='fu'><a href='https://rdrr.io/r/base/seq.html'>seq</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>20</span>, by <span class='op'>=</span> <span class='fl'>0.1</span><span class='op'>)</span>, - solution_type <span class='op'>=</span> <span class='st'>"eigen"</span><span class='op'>)</span><span class='op'>[</span><span class='fl'>201</span>,<span class='op'>]</span>, - deSolve_compiled <span class='op'>=</span> <span class='fu'>mkinpredict</span><span class='op'>(</span><span class='va'>SFO_SFO</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_parent <span class='op'>=</span> <span class='fl'>0.15</span>, f_parent_to_m1 <span class='op'>=</span> <span class='fl'>0.5</span>, k_m1 <span class='op'>=</span> <span class='fl'>0.01</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>100</span>, m1 <span class='op'>=</span> <span class='fl'>0</span><span class='op'>)</span>, <span class='fu'><a href='https://rdrr.io/r/base/seq.html'>seq</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>20</span>, by <span class='op'>=</span> <span class='fl'>0.1</span><span class='op'>)</span>, - solution_type <span class='op'>=</span> <span class='st'>"deSolve"</span><span class='op'>)</span><span class='op'>[</span><span class='fl'>201</span>,<span class='op'>]</span>, - deSolve <span class='op'>=</span> <span class='fu'>mkinpredict</span><span class='op'>(</span><span class='va'>SFO_SFO</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_parent <span class='op'>=</span> <span class='fl'>0.15</span>, f_parent_to_m1 <span class='op'>=</span> <span class='fl'>0.5</span>, k_m1 <span class='op'>=</span> <span class='fl'>0.01</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>100</span>, m1 <span class='op'>=</span> <span class='fl'>0</span><span class='op'>)</span>, <span class='fu'><a href='https://rdrr.io/r/base/seq.html'>seq</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>20</span>, by <span class='op'>=</span> <span class='fl'>0.1</span><span class='op'>)</span>, - solution_type <span class='op'>=</span> <span class='st'>"deSolve"</span>, use_compiled <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span><span class='op'>[</span><span class='fl'>201</span>,<span class='op'>]</span>, - analytical <span class='op'>=</span> <span class='fu'>mkinpredict</span><span class='op'>(</span><span class='va'>SFO_SFO</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_parent <span class='op'>=</span> <span class='fl'>0.15</span>, f_parent_to_m1 <span class='op'>=</span> <span class='fl'>0.5</span>, k_m1 <span class='op'>=</span> <span class='fl'>0.01</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>100</span>, m1 <span class='op'>=</span> <span class='fl'>0</span><span class='op'>)</span>, <span class='fu'><a href='https://rdrr.io/r/base/seq.html'>seq</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>20</span>, by <span class='op'>=</span> <span class='fl'>0.1</span><span class='op'>)</span>, - solution_type <span class='op'>=</span> <span class='st'>"analytical"</span>, use_compiled <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span><span class='op'>[</span><span class='fl'>201</span>,<span class='op'>]</span><span class='op'>)</span> -<span class='op'>}</span> -</div><div class='output co'>#> test relative elapsed -#> 2 deSolve_compiled 1.0 0.005 -#> 4 analytical 1.0 0.005 -#> 1 eigen 4.0 0.020 -#> 3 deSolve 46.2 0.231</div><div class='input'> -<span class='co'># \dontrun{</span> - <span class='co'># Predict from a fitted model</span> - <span class='va'>f</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_2006_C</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - <span class='va'>f</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_2006_C</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, solution_type <span class='op'>=</span> <span class='st'>"deSolve"</span><span class='op'>)</span> - <span class='fu'><a href='https://rdrr.io/r/utils/head.html'>head</a></span><span class='op'>(</span><span class='fu'>mkinpredict</span><span class='op'>(</span><span class='va'>f</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> time parent m1 -#> 0 0.0 82.49216 0.000000 -#> 0.1 0.1 80.00562 1.236394 -#> 0.2 0.2 77.59404 2.423201 -#> 0.3 0.3 75.25514 3.562040 -#> 0.4 0.4 72.98675 4.654478 -#> 0.5 0.5 70.78673 5.702033</div><div class='input'><span class='co'># }</span> - -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="va">SFO</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>degradinol <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># Compare solution types</span></span> +<span class="r-in"><span class="fu">mkinpredict</span><span class="op">(</span><span class="va">SFO</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_degradinol <span class="op">=</span> <span class="fl">0.3</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>degradinol <span class="op">=</span> <span class="fl">100</span><span class="op">)</span>, <span class="fl">0</span><span class="op">:</span><span class="fl">20</span>,</span> +<span class="r-in"> solution_type <span class="op">=</span> <span class="st">"analytical"</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> time degradinol</span> +<span class="r-out co"><span class="r-pr">#></span> 0 0 100.0000000</span> +<span class="r-out co"><span class="r-pr">#></span> 1 1 74.0818221</span> +<span class="r-out co"><span class="r-pr">#></span> 2 2 54.8811636</span> +<span class="r-out co"><span class="r-pr">#></span> 3 3 40.6569660</span> +<span class="r-out co"><span class="r-pr">#></span> 4 4 30.1194212</span> +<span class="r-out co"><span class="r-pr">#></span> 5 5 22.3130160</span> +<span class="r-out co"><span class="r-pr">#></span> 6 6 16.5298888</span> +<span class="r-out co"><span class="r-pr">#></span> 7 7 12.2456428</span> +<span class="r-out co"><span class="r-pr">#></span> 8 8 9.0717953</span> +<span class="r-out co"><span class="r-pr">#></span> 9 9 6.7205513</span> +<span class="r-out co"><span class="r-pr">#></span> 10 10 4.9787068</span> +<span class="r-out co"><span class="r-pr">#></span> 11 11 3.6883167</span> +<span class="r-out co"><span class="r-pr">#></span> 12 12 2.7323722</span> +<span class="r-out co"><span class="r-pr">#></span> 13 13 2.0241911</span> +<span class="r-out co"><span class="r-pr">#></span> 14 14 1.4995577</span> +<span class="r-out co"><span class="r-pr">#></span> 15 15 1.1108997</span> +<span class="r-out co"><span class="r-pr">#></span> 16 16 0.8229747</span> +<span class="r-out co"><span class="r-pr">#></span> 17 17 0.6096747</span> +<span class="r-out co"><span class="r-pr">#></span> 18 18 0.4516581</span> +<span class="r-out co"><span class="r-pr">#></span> 19 19 0.3345965</span> +<span class="r-out co"><span class="r-pr">#></span> 20 20 0.2478752</span> +<span class="r-in"><span class="fu">mkinpredict</span><span class="op">(</span><span class="va">SFO</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_degradinol <span class="op">=</span> <span class="fl">0.3</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>degradinol <span class="op">=</span> <span class="fl">100</span><span class="op">)</span>, <span class="fl">0</span><span class="op">:</span><span class="fl">20</span>,</span> +<span class="r-in"> solution_type <span class="op">=</span> <span class="st">"deSolve"</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> time degradinol</span> +<span class="r-out co"><span class="r-pr">#></span> 0 0 100.0000000</span> +<span class="r-out co"><span class="r-pr">#></span> 1 1 74.0818221</span> +<span class="r-out co"><span class="r-pr">#></span> 2 2 54.8811636</span> +<span class="r-out co"><span class="r-pr">#></span> 3 3 40.6569660</span> +<span class="r-out co"><span class="r-pr">#></span> 4 4 30.1194212</span> +<span class="r-out co"><span class="r-pr">#></span> 5 5 22.3130160</span> +<span class="r-out co"><span class="r-pr">#></span> 6 6 16.5298888</span> +<span class="r-out co"><span class="r-pr">#></span> 7 7 12.2456428</span> +<span class="r-out co"><span class="r-pr">#></span> 8 8 9.0717953</span> +<span class="r-out co"><span class="r-pr">#></span> 9 9 6.7205513</span> +<span class="r-out co"><span class="r-pr">#></span> 10 10 4.9787068</span> +<span class="r-out co"><span class="r-pr">#></span> 11 11 3.6883167</span> +<span class="r-out co"><span class="r-pr">#></span> 12 12 2.7323722</span> +<span class="r-out co"><span class="r-pr">#></span> 13 13 2.0241911</span> +<span class="r-out co"><span class="r-pr">#></span> 14 14 1.4995577</span> +<span class="r-out co"><span class="r-pr">#></span> 15 15 1.1108996</span> +<span class="r-out co"><span class="r-pr">#></span> 16 16 0.8229747</span> +<span class="r-out co"><span class="r-pr">#></span> 17 17 0.6096747</span> +<span class="r-out co"><span class="r-pr">#></span> 18 18 0.4516581</span> +<span class="r-out co"><span class="r-pr">#></span> 19 19 0.3345965</span> +<span class="r-out co"><span class="r-pr">#></span> 20 20 0.2478752</span> +<span class="r-in"><span class="fu">mkinpredict</span><span class="op">(</span><span class="va">SFO</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_degradinol <span class="op">=</span> <span class="fl">0.3</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>degradinol <span class="op">=</span> <span class="fl">100</span><span class="op">)</span>, <span class="fl">0</span><span class="op">:</span><span class="fl">20</span>,</span> +<span class="r-in"> solution_type <span class="op">=</span> <span class="st">"deSolve"</span>, use_compiled <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> time degradinol</span> +<span class="r-out co"><span class="r-pr">#></span> 0 0 100.0000000</span> +<span class="r-out co"><span class="r-pr">#></span> 1 1 74.0818221</span> +<span class="r-out co"><span class="r-pr">#></span> 2 2 54.8811636</span> +<span class="r-out co"><span class="r-pr">#></span> 3 3 40.6569660</span> +<span class="r-out co"><span class="r-pr">#></span> 4 4 30.1194212</span> +<span class="r-out co"><span class="r-pr">#></span> 5 5 22.3130160</span> +<span class="r-out co"><span class="r-pr">#></span> 6 6 16.5298888</span> +<span class="r-out co"><span class="r-pr">#></span> 7 7 12.2456428</span> +<span class="r-out co"><span class="r-pr">#></span> 8 8 9.0717953</span> +<span class="r-out co"><span class="r-pr">#></span> 9 9 6.7205513</span> +<span class="r-out co"><span class="r-pr">#></span> 10 10 4.9787068</span> +<span class="r-out co"><span class="r-pr">#></span> 11 11 3.6883167</span> +<span class="r-out co"><span class="r-pr">#></span> 12 12 2.7323722</span> +<span class="r-out co"><span class="r-pr">#></span> 13 13 2.0241911</span> +<span class="r-out co"><span class="r-pr">#></span> 14 14 1.4995577</span> +<span class="r-out co"><span class="r-pr">#></span> 15 15 1.1108996</span> +<span class="r-out co"><span class="r-pr">#></span> 16 16 0.8229747</span> +<span class="r-out co"><span class="r-pr">#></span> 17 17 0.6096747</span> +<span class="r-out co"><span class="r-pr">#></span> 18 18 0.4516581</span> +<span class="r-out co"><span class="r-pr">#></span> 19 19 0.3345965</span> +<span class="r-out co"><span class="r-pr">#></span> 20 20 0.2478752</span> +<span class="r-in"><span class="fu">mkinpredict</span><span class="op">(</span><span class="va">SFO</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_degradinol <span class="op">=</span> <span class="fl">0.3</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>degradinol <span class="op">=</span> <span class="fl">100</span><span class="op">)</span>, <span class="fl">0</span><span class="op">:</span><span class="fl">20</span>,</span> +<span class="r-in"> solution_type <span class="op">=</span> <span class="st">"eigen"</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> time degradinol</span> +<span class="r-out co"><span class="r-pr">#></span> 0 0 100.0000000</span> +<span class="r-out co"><span class="r-pr">#></span> 1 1 74.0818221</span> +<span class="r-out co"><span class="r-pr">#></span> 2 2 54.8811636</span> +<span class="r-out co"><span class="r-pr">#></span> 3 3 40.6569660</span> +<span class="r-out co"><span class="r-pr">#></span> 4 4 30.1194212</span> +<span class="r-out co"><span class="r-pr">#></span> 5 5 22.3130160</span> +<span class="r-out co"><span class="r-pr">#></span> 6 6 16.5298888</span> +<span class="r-out co"><span class="r-pr">#></span> 7 7 12.2456428</span> +<span class="r-out co"><span class="r-pr">#></span> 8 8 9.0717953</span> +<span class="r-out co"><span class="r-pr">#></span> 9 9 6.7205513</span> +<span class="r-out co"><span class="r-pr">#></span> 10 10 4.9787068</span> +<span class="r-out co"><span class="r-pr">#></span> 11 11 3.6883167</span> +<span class="r-out co"><span class="r-pr">#></span> 12 12 2.7323722</span> +<span class="r-out co"><span class="r-pr">#></span> 13 13 2.0241911</span> +<span class="r-out co"><span class="r-pr">#></span> 14 14 1.4995577</span> +<span class="r-out co"><span class="r-pr">#></span> 15 15 1.1108997</span> +<span class="r-out co"><span class="r-pr">#></span> 16 16 0.8229747</span> +<span class="r-out co"><span class="r-pr">#></span> 17 17 0.6096747</span> +<span class="r-out co"><span class="r-pr">#></span> 18 18 0.4516581</span> +<span class="r-out co"><span class="r-pr">#></span> 19 19 0.3345965</span> +<span class="r-out co"><span class="r-pr">#></span> 20 20 0.2478752</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Compare integration methods to analytical solution</span></span> +<span class="r-in"><span class="fu">mkinpredict</span><span class="op">(</span><span class="va">SFO</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_degradinol <span class="op">=</span> <span class="fl">0.3</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>degradinol <span class="op">=</span> <span class="fl">100</span><span class="op">)</span>, <span class="fl">0</span><span class="op">:</span><span class="fl">20</span>,</span> +<span class="r-in"> solution_type <span class="op">=</span> <span class="st">"analytical"</span><span class="op">)</span><span class="op">[</span><span class="fl">21</span>,<span class="op">]</span></span> +<span class="r-out co"><span class="r-pr">#></span> time degradinol </span> +<span class="r-out co"><span class="r-pr">#></span> 20.0000000 0.2478752 </span> +<span class="r-in"><span class="fu">mkinpredict</span><span class="op">(</span><span class="va">SFO</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_degradinol <span class="op">=</span> <span class="fl">0.3</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>degradinol <span class="op">=</span> <span class="fl">100</span><span class="op">)</span>, <span class="fl">0</span><span class="op">:</span><span class="fl">20</span>,</span> +<span class="r-in"> method <span class="op">=</span> <span class="st">"lsoda"</span><span class="op">)</span><span class="op">[</span><span class="fl">21</span>,<span class="op">]</span></span> +<span class="r-out co"><span class="r-pr">#></span> time degradinol </span> +<span class="r-out co"><span class="r-pr">#></span> 20.0000000 0.2478752 </span> +<span class="r-in"><span class="fu">mkinpredict</span><span class="op">(</span><span class="va">SFO</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_degradinol <span class="op">=</span> <span class="fl">0.3</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>degradinol <span class="op">=</span> <span class="fl">100</span><span class="op">)</span>, <span class="fl">0</span><span class="op">:</span><span class="fl">20</span>,</span> +<span class="r-in"> method <span class="op">=</span> <span class="st">"ode45"</span><span class="op">)</span><span class="op">[</span><span class="fl">21</span>,<span class="op">]</span></span> +<span class="r-out co"><span class="r-pr">#></span> time degradinol </span> +<span class="r-out co"><span class="r-pr">#></span> 20.0000000 0.2478752 </span> +<span class="r-in"><span class="fu">mkinpredict</span><span class="op">(</span><span class="va">SFO</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_degradinol <span class="op">=</span> <span class="fl">0.3</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>degradinol <span class="op">=</span> <span class="fl">100</span><span class="op">)</span>, <span class="fl">0</span><span class="op">:</span><span class="fl">20</span>,</span> +<span class="r-in"> method <span class="op">=</span> <span class="st">"rk4"</span><span class="op">)</span><span class="op">[</span><span class="fl">21</span>,<span class="op">]</span></span> +<span class="r-out co"><span class="r-pr">#></span> time degradinol </span> +<span class="r-out co"><span class="r-pr">#></span> 20.0000000 0.2480043 </span> +<span class="r-in"><span class="co"># rk4 is not as precise here</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># The number of output times used to make a lot of difference until the</span></span> +<span class="r-in"><span class="co"># default for atol was adjusted</span></span> +<span class="r-in"><span class="fu">mkinpredict</span><span class="op">(</span><span class="va">SFO</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_degradinol <span class="op">=</span> <span class="fl">0.3</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>degradinol <span class="op">=</span> <span class="fl">100</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/seq.html" class="external-link">seq</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">20</span>, by <span class="op">=</span> <span class="fl">0.1</span><span class="op">)</span><span class="op">)</span><span class="op">[</span><span class="fl">201</span>,<span class="op">]</span></span> +<span class="r-out co"><span class="r-pr">#></span> time degradinol </span> +<span class="r-out co"><span class="r-pr">#></span> 20.0000000 0.2478752 </span> +<span class="r-in"><span class="fu">mkinpredict</span><span class="op">(</span><span class="va">SFO</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_degradinol <span class="op">=</span> <span class="fl">0.3</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>degradinol <span class="op">=</span> <span class="fl">100</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/seq.html" class="external-link">seq</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">20</span>, by <span class="op">=</span> <span class="fl">0.01</span><span class="op">)</span><span class="op">)</span><span class="op">[</span><span class="fl">2001</span>,<span class="op">]</span></span> +<span class="r-out co"><span class="r-pr">#></span> time degradinol </span> +<span class="r-out co"><span class="r-pr">#></span> 20.0000000 0.2478752 </span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Comparison of the performance of solution types</span></span> +<span class="r-in"><span class="va">SFO_SFO</span> <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"m1"</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>, use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="kw">if</span><span class="op">(</span><span class="kw"><a href="https://rdrr.io/r/base/library.html" class="external-link">require</a></span><span class="op">(</span><span class="va"><a href="http://rbenchmark.googlecode.com" class="external-link">rbenchmark</a></span><span class="op">)</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/pkg/rbenchmark/man/benchmark.html" class="external-link">benchmark</a></span><span class="op">(</span>replications <span class="op">=</span> <span class="fl">10</span>, order <span class="op">=</span> <span class="st">"relative"</span>, columns <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"test"</span>, <span class="st">"relative"</span>, <span class="st">"elapsed"</span><span class="op">)</span>,</span> +<span class="r-in"> eigen <span class="op">=</span> <span class="fu">mkinpredict</span><span class="op">(</span><span class="va">SFO_SFO</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_parent <span class="op">=</span> <span class="fl">0.15</span>, f_parent_to_m1 <span class="op">=</span> <span class="fl">0.5</span>, k_m1 <span class="op">=</span> <span class="fl">0.01</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span>, m1 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/seq.html" class="external-link">seq</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">20</span>, by <span class="op">=</span> <span class="fl">0.1</span><span class="op">)</span>,</span> +<span class="r-in"> solution_type <span class="op">=</span> <span class="st">"eigen"</span><span class="op">)</span><span class="op">[</span><span class="fl">201</span>,<span class="op">]</span>,</span> +<span class="r-in"> deSolve_compiled <span class="op">=</span> <span class="fu">mkinpredict</span><span class="op">(</span><span class="va">SFO_SFO</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_parent <span class="op">=</span> <span class="fl">0.15</span>, f_parent_to_m1 <span class="op">=</span> <span class="fl">0.5</span>, k_m1 <span class="op">=</span> <span class="fl">0.01</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span>, m1 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/seq.html" class="external-link">seq</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">20</span>, by <span class="op">=</span> <span class="fl">0.1</span><span class="op">)</span>,</span> +<span class="r-in"> solution_type <span class="op">=</span> <span class="st">"deSolve"</span><span class="op">)</span><span class="op">[</span><span class="fl">201</span>,<span class="op">]</span>,</span> +<span class="r-in"> deSolve <span class="op">=</span> <span class="fu">mkinpredict</span><span class="op">(</span><span class="va">SFO_SFO</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_parent <span class="op">=</span> <span class="fl">0.15</span>, f_parent_to_m1 <span class="op">=</span> <span class="fl">0.5</span>, k_m1 <span class="op">=</span> <span class="fl">0.01</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span>, m1 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/seq.html" class="external-link">seq</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">20</span>, by <span class="op">=</span> <span class="fl">0.1</span><span class="op">)</span>,</span> +<span class="r-in"> solution_type <span class="op">=</span> <span class="st">"deSolve"</span>, use_compiled <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span><span class="op">[</span><span class="fl">201</span>,<span class="op">]</span>,</span> +<span class="r-in"> analytical <span class="op">=</span> <span class="fu">mkinpredict</span><span class="op">(</span><span class="va">SFO_SFO</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_parent <span class="op">=</span> <span class="fl">0.15</span>, f_parent_to_m1 <span class="op">=</span> <span class="fl">0.5</span>, k_m1 <span class="op">=</span> <span class="fl">0.01</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span>, m1 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/seq.html" class="external-link">seq</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">20</span>, by <span class="op">=</span> <span class="fl">0.1</span><span class="op">)</span>,</span> +<span class="r-in"> solution_type <span class="op">=</span> <span class="st">"analytical"</span>, use_compiled <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span><span class="op">[</span><span class="fl">201</span>,<span class="op">]</span><span class="op">)</span></span> +<span class="r-in"><span class="op">}</span></span> +<span class="r-out co"><span class="r-pr">#></span> test relative elapsed</span> +<span class="r-out co"><span class="r-pr">#></span> 4 analytical 1.0 0.005</span> +<span class="r-out co"><span class="r-pr">#></span> 2 deSolve_compiled 1.2 0.006</span> +<span class="r-out co"><span class="r-pr">#></span> 1 eigen 4.2 0.021</span> +<span class="r-out co"><span class="r-pr">#></span> 3 deSolve 40.8 0.204</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"> <span class="co"># Predict from a fitted model</span></span> +<span class="r-in"> <span class="va">f</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_2006_C</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">f</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_2006_C</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, solution_type <span class="op">=</span> <span class="st">"deSolve"</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/utils/head.html" class="external-link">head</a></span><span class="op">(</span><span class="fu">mkinpredict</span><span class="op">(</span><span class="va">f</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> time parent m1</span> +<span class="r-out co"><span class="r-pr">#></span> 0 0.0 82.49216 0.000000</span> +<span class="r-out co"><span class="r-pr">#></span> 0.1 0.1 80.00562 1.236394</span> +<span class="r-out co"><span class="r-pr">#></span> 0.2 0.2 77.59404 2.423201</span> +<span class="r-out co"><span class="r-pr">#></span> 0.3 0.3 75.25514 3.562040</span> +<span class="r-out co"><span class="r-pr">#></span> 0.4 0.4 72.98675 4.654478</span> +<span class="r-out co"><span class="r-pr">#></span> 0.5 0.5 70.78673 5.702033</span> +<span class="r-in"><span class="co"># }</span></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/mkinresplot-1.png b/docs/reference/mkinresplot-1.png Binary files differindex 963aa5b7..97ccd762 100644 --- a/docs/reference/mkinresplot-1.png +++ b/docs/reference/mkinresplot-1.png diff --git a/docs/reference/mkinresplot.html b/docs/reference/mkinresplot.html index fe3150e7..54d612ef 100644 --- a/docs/reference/mkinresplot.html +++ b/docs/reference/mkinresplot.html @@ -1,70 +1,15 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Function to plot residuals stored in an mkin object — mkinresplot • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Function to plot residuals stored in an mkin object — mkinresplot" /> -<meta property="og:description" content="This function plots the residuals for the specified subset of the observed +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Function to plot residuals stored in an mkin object — mkinresplot • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Function to plot residuals stored in an mkin object — mkinresplot"><meta property="og:description" content="This function plots the residuals for the specified subset of the observed variables from an mkinfit object. A combined plot of the fitted model and the residuals can be obtained using plot.mkinfit using the -argument show_residuals = TRUE." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +argument show_residuals = TRUE."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -75,13 +20,12 @@ argument show_residuals = TRUE." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -90,8 +34,7 @@ argument show_residuals = TRUE." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -101,6 +44,9 @@ argument show_residuals = TRUE." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -115,167 +61,137 @@ argument show_residuals = TRUE." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Function to plot residuals stored in an mkin object</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/mkinresplot.R'><code>R/mkinresplot.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/mkinresplot.R" class="external-link"><code>R/mkinresplot.R</code></a></small> <div class="hidden name"><code>mkinresplot.Rd</code></div> </div> <div class="ref-description"> <p>This function plots the residuals for the specified subset of the observed variables from an mkinfit object. A combined plot of the fitted model and -the residuals can be obtained using <code><a href='plot.mkinfit.html'>plot.mkinfit</a></code> using the +the residuals can be obtained using <code><a href="plot.mkinfit.html">plot.mkinfit</a></code> using the argument <code>show_residuals = TRUE</code>.</p> </div> - <pre class="usage"><span class='fu'>mkinresplot</span><span class='op'>(</span> - <span class='va'>object</span>, - obs_vars <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/names.html'>names</a></span><span class='op'>(</span><span class='va'>object</span><span class='op'>$</span><span class='va'>mkinmod</span><span class='op'>$</span><span class='va'>map</span><span class='op'>)</span>, - xlim <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>1.1</span> <span class='op'>*</span> <span class='fu'><a href='https://rdrr.io/r/base/Extremes.html'>max</a></span><span class='op'>(</span><span class='va'>object</span><span class='op'>$</span><span class='va'>data</span><span class='op'>$</span><span class='va'>time</span><span class='op'>)</span><span class='op'>)</span>, - standardized <span class='op'>=</span> <span class='cn'>FALSE</span>, - xlab <span class='op'>=</span> <span class='st'>"Time"</span>, - ylab <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/ifelse.html'>ifelse</a></span><span class='op'>(</span><span class='va'>standardized</span>, <span class='st'>"Standardized residual"</span>, <span class='st'>"Residual"</span><span class='op'>)</span>, - maxabs <span class='op'>=</span> <span class='st'>"auto"</span>, - legend <span class='op'>=</span> <span class='cn'>TRUE</span>, - lpos <span class='op'>=</span> <span class='st'>"topright"</span>, - col_obs <span class='op'>=</span> <span class='st'>"auto"</span>, - pch_obs <span class='op'>=</span> <span class='st'>"auto"</span>, - frame <span class='op'>=</span> <span class='cn'>TRUE</span>, - <span class='va'>...</span> -<span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">mkinresplot</span><span class="op">(</span> + <span class="va">object</span>, + obs_vars <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">object</span><span class="op">$</span><span class="va">mkinmod</span><span class="op">$</span><span class="va">map</span><span class="op">)</span>, + xlim <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">1.1</span> <span class="op">*</span> <span class="fu"><a href="https://rdrr.io/r/base/Extremes.html" class="external-link">max</a></span><span class="op">(</span><span class="va">object</span><span class="op">$</span><span class="va">data</span><span class="op">$</span><span class="va">time</span><span class="op">)</span><span class="op">)</span>, + standardized <span class="op">=</span> <span class="cn">FALSE</span>, + xlab <span class="op">=</span> <span class="st">"Time"</span>, + ylab <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/ifelse.html" class="external-link">ifelse</a></span><span class="op">(</span><span class="va">standardized</span>, <span class="st">"Standardized residual"</span>, <span class="st">"Residual"</span><span class="op">)</span>, + maxabs <span class="op">=</span> <span class="st">"auto"</span>, + legend <span class="op">=</span> <span class="cn">TRUE</span>, + lpos <span class="op">=</span> <span class="st">"topright"</span>, + col_obs <span class="op">=</span> <span class="st">"auto"</span>, + pch_obs <span class="op">=</span> <span class="st">"auto"</span>, + frame <span class="op">=</span> <span class="cn">TRUE</span>, + <span class="va">...</span> +<span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>A fit represented in an <code><a href='mkinfit.html'>mkinfit</a></code> object.</p></td> - </tr> - <tr> - <th>obs_vars</th> - <td><p>A character vector of names of the observed variables for + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>A fit represented in an <code><a href="mkinfit.html">mkinfit</a></code> object.</p></dd> +<dt>obs_vars</dt> +<dd><p>A character vector of names of the observed variables for which residuals should be plotted. Defaults to all observed variables in -the model</p></td> - </tr> - <tr> - <th>xlim</th> - <td><p>plot range in x direction.</p></td> - </tr> - <tr> - <th>standardized</th> - <td><p>Should the residuals be standardized by dividing by the -standard deviation given by the error model of the fit?</p></td> - </tr> - <tr> - <th>xlab</th> - <td><p>Label for the x axis.</p></td> - </tr> - <tr> - <th>ylab</th> - <td><p>Label for the y axis.</p></td> - </tr> - <tr> - <th>maxabs</th> - <td><p>Maximum absolute value of the residuals. This is used for the -scaling of the y axis and defaults to "auto".</p></td> - </tr> - <tr> - <th>legend</th> - <td><p>Should a legend be plotted?</p></td> - </tr> - <tr> - <th>lpos</th> - <td><p>Where should the legend be placed? Default is "topright". Will -be passed on to <code><a href='https://rdrr.io/r/graphics/legend.html'>legend</a></code>.</p></td> - </tr> - <tr> - <th>col_obs</th> - <td><p>Colors for the observed variables.</p></td> - </tr> - <tr> - <th>pch_obs</th> - <td><p>Symbols to be used for the observed variables.</p></td> - </tr> - <tr> - <th>frame</th> - <td><p>Should a frame be drawn around the plots?</p></td> - </tr> - <tr> - <th>...</th> - <td><p>further arguments passed to <code><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></code>.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - +the model</p></dd> +<dt>xlim</dt> +<dd><p>plot range in x direction.</p></dd> +<dt>standardized</dt> +<dd><p>Should the residuals be standardized by dividing by the +standard deviation given by the error model of the fit?</p></dd> +<dt>xlab</dt> +<dd><p>Label for the x axis.</p></dd> +<dt>ylab</dt> +<dd><p>Label for the y axis.</p></dd> +<dt>maxabs</dt> +<dd><p>Maximum absolute value of the residuals. This is used for the +scaling of the y axis and defaults to "auto".</p></dd> +<dt>legend</dt> +<dd><p>Should a legend be plotted?</p></dd> +<dt>lpos</dt> +<dd><p>Where should the legend be placed? Default is "topright". Will +be passed on to <code><a href="https://rdrr.io/r/graphics/legend.html" class="external-link">legend</a></code>.</p></dd> +<dt>col_obs</dt> +<dd><p>Colors for the observed variables.</p></dd> +<dt>pch_obs</dt> +<dd><p>Symbols to be used for the observed variables.</p></dd> +<dt>frame</dt> +<dd><p>Should a frame be drawn around the plots?</p></dd> +<dt>...</dt> +<dd><p>further arguments passed to <code><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></code>.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>Nothing is returned by this function, as it is called for its side effect, namely to produce a plot.</p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p><code><a href='mkinplot.html'>mkinplot</a></code>, for a way to plot the data and the fitted -lines of the mkinfit object, and <code><a href='plot.mkinfit.html'>plot_res</a></code> for a function + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p><code><a href="mkinplot.html">mkinplot</a></code>, for a way to plot the data and the fitted +lines of the mkinfit object, and <code><a href="plot.mkinfit.html">plot_res</a></code> for a function combining the plot of the fit and the residual plot.</p></div> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke and Katrin Lindenberger</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='va'>model</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"m1"</span><span class='op'>)</span>, m1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'><span class='va'>fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>model</span>, <span class='va'>FOCUS_2006_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='warning'>Warning: Observations with value of zero were removed from the data</span></div><div class='input'><span class='fu'>mkinresplot</span><span class='op'>(</span><span class='va'>fit</span>, <span class='st'>"m1"</span><span class='op'>)</span> -</div><div class='img'><img src='mkinresplot-1.png' alt='' width='700' height='433' /></div><div class='input'> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="va">model</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"m1"</span><span class="op">)</span>, m1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="va">fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">model</span>, <span class="va">FOCUS_2006_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu">mkinresplot</span><span class="op">(</span><span class="va">fit</span>, <span class="st">"m1"</span><span class="op">)</span></span> +<span class="r-plt img"><img src="mkinresplot-1.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/mmkin-1.png b/docs/reference/mmkin-1.png Binary files differindex 701a6d6a..8ad9c11d 100644 --- a/docs/reference/mmkin-1.png +++ b/docs/reference/mmkin-1.png diff --git a/docs/reference/mmkin-2.png b/docs/reference/mmkin-2.png Binary files differindex 5277b389..da2a48a8 100644 --- a/docs/reference/mmkin-2.png +++ b/docs/reference/mmkin-2.png diff --git a/docs/reference/mmkin-3.png b/docs/reference/mmkin-3.png Binary files differindex 2659cd61..10d3f35b 100644 --- a/docs/reference/mmkin-3.png +++ b/docs/reference/mmkin-3.png diff --git a/docs/reference/mmkin-4.png b/docs/reference/mmkin-4.png Binary files differindex ae16ee79..132380a8 100644 --- a/docs/reference/mmkin-4.png +++ b/docs/reference/mmkin-4.png diff --git a/docs/reference/mmkin-5.png b/docs/reference/mmkin-5.png Binary files differindex 2b9dc831..4bfcc55e 100644 --- a/docs/reference/mmkin-5.png +++ b/docs/reference/mmkin-5.png diff --git a/docs/reference/mmkin.html b/docs/reference/mmkin.html index d7989c6b..4012df67 100644 --- a/docs/reference/mmkin.html +++ b/docs/reference/mmkin.html @@ -1,70 +1,15 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Fit one or more kinetic models with one or more state variables to one or -more datasets — mmkin • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Fit one or more kinetic models with one or more state variables to one or -more datasets — mmkin" /> -<meta property="og:description" content="This function calls mkinfit on all combinations of models and -datasets specified in its first two arguments." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Fit one or more kinetic models with one or more state variables to one or +more datasets — mmkin • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Fit one or more kinetic models with one or more state variables to one or +more datasets — mmkin"><meta property="og:description" content="This function calls mkinfit on all combinations of models and +datasets specified in its first two arguments."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -75,13 +20,12 @@ datasets specified in its first two arguments." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -90,8 +34,7 @@ datasets specified in its first two arguments." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -101,6 +44,9 @@ datasets specified in its first two arguments." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -115,199 +61,191 @@ datasets specified in its first two arguments." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Fit one or more kinetic models with one or more state variables to one or more datasets</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/mmkin.R'><code>R/mmkin.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/mmkin.R" class="external-link"><code>R/mmkin.R</code></a></small> <div class="hidden name"><code>mmkin.Rd</code></div> </div> <div class="ref-description"> - <p>This function calls <code><a href='mkinfit.html'>mkinfit</a></code> on all combinations of models and + <p>This function calls <code><a href="mkinfit.html">mkinfit</a></code> on all combinations of models and datasets specified in its first two arguments.</p> </div> - <pre class="usage"><span class='fu'>mmkin</span><span class='op'>(</span> - models <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"FOMC"</span>, <span class='st'>"DFOP"</span><span class='op'>)</span>, - <span class='va'>datasets</span>, - cores <span class='op'>=</span> <span class='kw'>if</span> <span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/Sys.info.html'>Sys.info</a></span><span class='op'>(</span><span class='op'>)</span><span class='op'>[</span><span class='st'>"sysname"</span><span class='op'>]</span> <span class='op'>==</span> <span class='st'>"Windows"</span><span class='op'>)</span> <span class='fl'>1</span> <span class='kw'>else</span> <span class='fu'>parallel</span><span class='fu'>::</span><span class='fu'><a href='https://rdrr.io/r/parallel/detectCores.html'>detectCores</a></span><span class='op'>(</span><span class='op'>)</span>, - cluster <span class='op'>=</span> <span class='cn'>NULL</span>, - <span class='va'>...</span> -<span class='op'>)</span> - -<span class='co'># S3 method for mmkin</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>x</span>, <span class='va'>...</span><span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">mmkin</span><span class="op">(</span> + models <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"FOMC"</span>, <span class="st">"DFOP"</span><span class="op">)</span>, + <span class="va">datasets</span>, + cores <span class="op">=</span> <span class="kw">if</span> <span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/Sys.info.html" class="external-link">Sys.info</a></span><span class="op">(</span><span class="op">)</span><span class="op">[</span><span class="st">"sysname"</span><span class="op">]</span> <span class="op">==</span> <span class="st">"Windows"</span><span class="op">)</span> <span class="fl">1</span> <span class="kw">else</span> <span class="fu">parallel</span><span class="fu">::</span><span class="fu"><a href="https://rdrr.io/r/parallel/detectCores.html" class="external-link">detectCores</a></span><span class="op">(</span><span class="op">)</span>, + cluster <span class="op">=</span> <span class="cn">NULL</span>, + <span class="va">...</span> +<span class="op">)</span> + +<span class="co"># S3 method for mmkin</span> +<span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">x</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>models</th> - <td><p>Either a character vector of shorthand names like -<code><a href='https://rdrr.io/r/base/c.html'>c("SFO", "FOMC", "DFOP", "HS", "SFORB")</a></code>, or an optionally named -list of <code><a href='mkinmod.html'>mkinmod</a></code> objects.</p></td> - </tr> - <tr> - <th>datasets</th> - <td><p>An optionally named list of datasets suitable as observed -data for <code><a href='mkinfit.html'>mkinfit</a></code>.</p></td> - </tr> - <tr> - <th>cores</th> - <td><p>The number of cores to be used for multicore processing. This + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>models</dt> +<dd><p>Either a character vector of shorthand names like +<code>c("SFO", "FOMC", "DFOP", "HS", "SFORB")</code>, or an optionally named +list of <code><a href="mkinmod.html">mkinmod</a></code> objects.</p></dd> +<dt>datasets</dt> +<dd><p>An optionally named list of datasets suitable as observed +data for <code><a href="mkinfit.html">mkinfit</a></code>.</p></dd> +<dt>cores</dt> +<dd><p>The number of cores to be used for multicore processing. This is only used when the <code>cluster</code> argument is <code>NULL</code>. On Windows machines, cores > 1 is not supported, you need to use the <code>cluster</code> argument to use multiple logical processors. Per default, all cores -detected by <code><a href='https://rdrr.io/r/parallel/detectCores.html'>parallel::detectCores()</a></code> are used, except on Windows where -the default is 1.</p></td> - </tr> - <tr> - <th>cluster</th> - <td><p>A cluster as returned by <code>makeCluster</code> to be used -for parallel execution.</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Not used.</p></td> - </tr> - <tr> - <th>x</th> - <td><p>An mmkin object.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - - <p>A two-dimensional <code><a href='https://rdrr.io/r/base/array.html'>array</a></code> of <code><a href='mkinfit.html'>mkinfit</a></code> -objects and/or try-errors that can be indexed using the model names for the +detected by <code><a href="https://rdrr.io/r/parallel/detectCores.html" class="external-link">parallel::detectCores()</a></code> are used, except on Windows where +the default is 1.</p></dd> +<dt>cluster</dt> +<dd><p>A cluster as returned by <code><a href="https://rdrr.io/r/parallel/makeCluster.html" class="external-link">makeCluster</a></code> to be used +for parallel execution.</p></dd> +<dt>...</dt> +<dd><p>Not used.</p></dd> +<dt>x</dt> +<dd><p>An mmkin object.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>A two-dimensional <code><a href="https://rdrr.io/r/base/array.html" class="external-link">array</a></code> of <code><a href="mkinfit.html">mkinfit</a></code>objects and/or try-errors that can be indexed using the model names for the first index (row index) and the dataset names for the second index (column index).</p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p><code><a href='[.mmkin.html'>[.mmkin</a></code> for subsetting, <code><a href='plot.mmkin.html'>plot.mmkin</a></code> for + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p><code><a href="Extract.mmkin.html">[.mmkin</a></code> for subsetting, <code><a href="plot.mmkin.html">plot.mmkin</a></code> for plotting.</p></div> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='co'># \dontrun{</span> -<span class='va'>m_synth_SFO_lin</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"M1"</span><span class='op'>)</span>, - M1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"M2"</span><span class='op'>)</span>, - M2 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> -<span class='va'>m_synth_FOMC_lin</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"FOMC"</span>, <span class='st'>"M1"</span><span class='op'>)</span>, - M1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"M2"</span><span class='op'>)</span>, - M2 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> -<span class='va'>models</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>SFO_lin <span class='op'>=</span> <span class='va'>m_synth_SFO_lin</span>, FOMC_lin <span class='op'>=</span> <span class='va'>m_synth_FOMC_lin</span><span class='op'>)</span> -<span class='va'>datasets</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/lapply.html'>lapply</a></span><span class='op'>(</span><span class='va'>synthetic_data_for_UBA_2014</span><span class='op'>[</span><span class='fl'>1</span><span class='op'>:</span><span class='fl'>3</span><span class='op'>]</span>, <span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='va'>x</span><span class='op'>$</span><span class='va'>data</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/names.html'>names</a></span><span class='op'>(</span><span class='va'>datasets</span><span class='op'>)</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/paste.html'>paste</a></span><span class='op'>(</span><span class='st'>"Dataset"</span>, <span class='fl'>1</span><span class='op'>:</span><span class='fl'>3</span><span class='op'>)</span> - -<span class='va'>time_default</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/system.time.html'>system.time</a></span><span class='op'>(</span><span class='va'>fits.0</span> <span class='op'><-</span> <span class='fu'>mmkin</span><span class='op'>(</span><span class='va'>models</span>, <span class='va'>datasets</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span><span class='op'>)</span> -<span class='va'>time_1</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/system.time.html'>system.time</a></span><span class='op'>(</span><span class='va'>fits.4</span> <span class='op'><-</span> <span class='fu'>mmkin</span><span class='op'>(</span><span class='va'>models</span>, <span class='va'>datasets</span>, cores <span class='op'>=</span> <span class='fl'>1</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span><span class='op'>)</span> - -<span class='va'>time_default</span> -</div><div class='output co'>#> user system elapsed -#> 4.491 0.397 1.634 </div><div class='input'><span class='va'>time_1</span> -</div><div class='output co'>#> user system elapsed -#> 5.491 0.000 5.492 </div><div class='input'> -<span class='fu'><a href='endpoints.html'>endpoints</a></span><span class='op'>(</span><span class='va'>fits.0</span><span class='op'>[[</span><span class='st'>"SFO_lin"</span>, <span class='fl'>2</span><span class='op'>]</span><span class='op'>]</span><span class='op'>)</span> -</div><div class='output co'>#> $ff -#> parent_M1 parent_sink M1_M2 M1_sink -#> 0.7340481 0.2659519 0.7505683 0.2494317 -#> -#> $distimes -#> DT50 DT90 -#> parent 0.877769 2.915885 -#> M1 2.325744 7.725956 -#> M2 33.720100 112.015749 -#> </div><div class='input'> -<span class='co'># plot.mkinfit handles rows or columns of mmkin result objects</span> -<span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>fits.0</span><span class='op'>[</span><span class='fl'>1</span>, <span class='op'>]</span><span class='op'>)</span> -</div><div class='img'><img src='mmkin-1.png' alt='' width='700' height='433' /></div><div class='input'><span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>fits.0</span><span class='op'>[</span><span class='fl'>1</span>, <span class='op'>]</span>, obs_var <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"M1"</span>, <span class='st'>"M2"</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='img'><img src='mmkin-2.png' alt='' width='700' height='433' /></div><div class='input'><span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>fits.0</span><span class='op'>[</span>, <span class='fl'>1</span><span class='op'>]</span><span class='op'>)</span> -</div><div class='img'><img src='mmkin-3.png' alt='' width='700' height='433' /></div><div class='input'><span class='co'># Use double brackets to extract a single mkinfit object, which will be plotted</span> -<span class='co'># by plot.mkinfit and can be plotted using plot_sep</span> -<span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>fits.0</span><span class='op'>[[</span><span class='fl'>1</span>, <span class='fl'>1</span><span class='op'>]</span><span class='op'>]</span>, sep_obs <span class='op'>=</span> <span class='cn'>TRUE</span>, show_residuals <span class='op'>=</span> <span class='cn'>TRUE</span>, show_errmin <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='img'><img src='mmkin-4.png' alt='' width='700' height='433' /></div><div class='input'><span class='fu'><a href='plot.mkinfit.html'>plot_sep</a></span><span class='op'>(</span><span class='va'>fits.0</span><span class='op'>[[</span><span class='fl'>1</span>, <span class='fl'>1</span><span class='op'>]</span><span class='op'>]</span><span class='op'>)</span> -<span class='co'># Plotting with mmkin (single brackets, extracting an mmkin object) does not</span> -<span class='co'># allow to plot the observed variables separately</span> -<span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>fits.0</span><span class='op'>[</span><span class='fl'>1</span>, <span class='fl'>1</span><span class='op'>]</span><span class='op'>)</span> -</div><div class='img'><img src='mmkin-5.png' alt='' width='700' height='433' /></div><div class='input'> -<span class='co'># On Windows, we can use multiple cores by making a cluster using the parallel</span> -<span class='co'># package, which gets loaded with mkin, and passing it to mmkin, e.g.</span> -<span class='va'>cl</span> <span class='op'><-</span> <span class='fu'>makePSOCKcluster</span><span class='op'>(</span><span class='fl'>12</span><span class='op'>)</span> -<span class='va'>f</span> <span class='op'><-</span> <span class='fu'>mmkin</span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"FOMC"</span>, <span class='st'>"DFOP"</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>A <span class='op'>=</span> <span class='va'>FOCUS_2006_A</span>, B <span class='op'>=</span> <span class='va'>FOCUS_2006_B</span>, C <span class='op'>=</span> <span class='va'>FOCUS_2006_C</span>, D <span class='op'>=</span> <span class='va'>FOCUS_2006_D</span><span class='op'>)</span>, - cluster <span class='op'>=</span> <span class='va'>cl</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>f</span><span class='op'>)</span> -</div><div class='output co'>#> <mmkin> object -#> Status of individual fits: -#> -#> dataset -#> model A B C D -#> SFO OK OK OK OK -#> FOMC OK OK OK OK -#> DFOP OK OK OK OK -#> -#> OK: No warnings</div><div class='input'><span class='co'># We get false convergence for the FOMC fit to FOCUS_2006_A because this</span> -<span class='co'># dataset is really SFO, and the FOMC fit is overparameterised</span> -<span class='fu'>stopCluster</span><span class='op'>(</span><span class='va'>cl</span><span class='op'>)</span> -<span class='co'># }</span> - -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="va">m_synth_SFO_lin</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"M1"</span><span class="op">)</span>,</span> +<span class="r-in"> M1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"M2"</span><span class="op">)</span>,</span> +<span class="r-in"> M2 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>, use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">m_synth_FOMC_lin</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"FOMC"</span>, <span class="st">"M1"</span><span class="op">)</span>,</span> +<span class="r-in"> M1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"M2"</span><span class="op">)</span>,</span> +<span class="r-in"> M2 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>, use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">models</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>SFO_lin <span class="op">=</span> <span class="va">m_synth_SFO_lin</span>, FOMC_lin <span class="op">=</span> <span class="va">m_synth_FOMC_lin</span><span class="op">)</span></span> +<span class="r-in"><span class="va">datasets</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="va">synthetic_data_for_UBA_2014</span><span class="op">[</span><span class="fl">1</span><span class="op">:</span><span class="fl">3</span><span class="op">]</span>, <span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="va">x</span><span class="op">$</span><span class="va">data</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">datasets</span><span class="op">)</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste</a></span><span class="op">(</span><span class="st">"Dataset"</span>, <span class="fl">1</span><span class="op">:</span><span class="fl">3</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">time_default</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/system.time.html" class="external-link">system.time</a></span><span class="op">(</span><span class="va">fits.0</span> <span class="op"><-</span> <span class="fu">mmkin</span><span class="op">(</span><span class="va">models</span>, <span class="va">datasets</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="va">time_1</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/system.time.html" class="external-link">system.time</a></span><span class="op">(</span><span class="va">fits.4</span> <span class="op"><-</span> <span class="fu">mmkin</span><span class="op">(</span><span class="va">models</span>, <span class="va">datasets</span>, cores <span class="op">=</span> <span class="fl">1</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">time_default</span></span> +<span class="r-out co"><span class="r-pr">#></span> user system elapsed </span> +<span class="r-out co"><span class="r-pr">#></span> 6.055 1.405 2.191 </span> +<span class="r-in"><span class="va">time_1</span></span> +<span class="r-out co"><span class="r-pr">#></span> user system elapsed </span> +<span class="r-out co"><span class="r-pr">#></span> 6.746 0.004 6.750 </span> +<span class="r-in"></span> +<span class="r-in"><span class="fu"><a href="endpoints.html">endpoints</a></span><span class="op">(</span><span class="va">fits.0</span><span class="op">[[</span><span class="st">"SFO_lin"</span>, <span class="fl">2</span><span class="op">]</span><span class="op">]</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> $ff</span> +<span class="r-out co"><span class="r-pr">#></span> parent_M1 parent_sink M1_M2 M1_sink </span> +<span class="r-out co"><span class="r-pr">#></span> 0.7340481 0.2659519 0.7505683 0.2494317 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $distimes</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90</span> +<span class="r-out co"><span class="r-pr">#></span> parent 0.877769 2.915885</span> +<span class="r-out co"><span class="r-pr">#></span> M1 2.325744 7.725956</span> +<span class="r-out co"><span class="r-pr">#></span> M2 33.720100 112.015749</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># plot.mkinfit handles rows or columns of mmkin result objects</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">fits.0</span><span class="op">[</span><span class="fl">1</span>, <span class="op">]</span><span class="op">)</span></span> +<span class="r-plt img"><img src="mmkin-1.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">fits.0</span><span class="op">[</span><span class="fl">1</span>, <span class="op">]</span>, obs_var <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"M1"</span>, <span class="st">"M2"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-plt img"><img src="mmkin-2.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">fits.0</span><span class="op">[</span>, <span class="fl">1</span><span class="op">]</span><span class="op">)</span></span> +<span class="r-plt img"><img src="mmkin-3.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="co"># Use double brackets to extract a single mkinfit object, which will be plotted</span></span> +<span class="r-in"><span class="co"># by plot.mkinfit and can be plotted using plot_sep</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">fits.0</span><span class="op">[[</span><span class="fl">1</span>, <span class="fl">1</span><span class="op">]</span><span class="op">]</span>, sep_obs <span class="op">=</span> <span class="cn">TRUE</span>, show_residuals <span class="op">=</span> <span class="cn">TRUE</span>, show_errmin <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-plt img"><img src="mmkin-4.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="fu"><a href="plot.mkinfit.html">plot_sep</a></span><span class="op">(</span><span class="va">fits.0</span><span class="op">[[</span><span class="fl">1</span>, <span class="fl">1</span><span class="op">]</span><span class="op">]</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># Plotting with mmkin (single brackets, extracting an mmkin object) does not</span></span> +<span class="r-in"><span class="co"># allow to plot the observed variables separately</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">fits.0</span><span class="op">[</span><span class="fl">1</span>, <span class="fl">1</span><span class="op">]</span><span class="op">)</span></span> +<span class="r-plt img"><img src="mmkin-5.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># On Windows, we can use multiple cores by making a cluster using the parallel</span></span> +<span class="r-in"><span class="co"># package, which gets loaded with mkin, and passing it to mmkin, e.g.</span></span> +<span class="r-in"><span class="va">cl</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/parallel/makeCluster.html" class="external-link">makePSOCKcluster</a></span><span class="op">(</span><span class="fl">12</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f</span> <span class="op"><-</span> <span class="fu">mmkin</span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"FOMC"</span>, <span class="st">"DFOP"</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>A <span class="op">=</span> <span class="va">FOCUS_2006_A</span>, B <span class="op">=</span> <span class="va">FOCUS_2006_B</span>, C <span class="op">=</span> <span class="va">FOCUS_2006_C</span>, D <span class="op">=</span> <span class="va">FOCUS_2006_D</span><span class="op">)</span>,</span> +<span class="r-in"> cluster <span class="op">=</span> <span class="va">cl</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">f</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> <mmkin> object</span> +<span class="r-out co"><span class="r-pr">#></span> Status of individual fits:</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> dataset</span> +<span class="r-out co"><span class="r-pr">#></span> model A B C D </span> +<span class="r-out co"><span class="r-pr">#></span> SFO OK OK OK OK</span> +<span class="r-out co"><span class="r-pr">#></span> FOMC OK OK OK OK</span> +<span class="r-out co"><span class="r-pr">#></span> DFOP OK OK OK OK</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> OK: No warnings</span> +<span class="r-in"><span class="co"># We get false convergence for the FOMC fit to FOCUS_2006_A because this</span></span> +<span class="r-in"><span class="co"># dataset is really SFO, and the FOMC fit is overparameterised</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/parallel/makeCluster.html" class="external-link">stopCluster</a></span><span class="op">(</span><span class="va">cl</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># }</span></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/nafta-1.png b/docs/reference/nafta-1.png Binary files differindex 4f0d7833..5d2d434b 100644 --- a/docs/reference/nafta-1.png +++ b/docs/reference/nafta-1.png diff --git a/docs/reference/nafta.html b/docs/reference/nafta.html index 29e03251..28e44864 100644 --- a/docs/reference/nafta.html +++ b/docs/reference/nafta.html @@ -1,71 +1,16 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Evaluate parent kinetics using the NAFTA guidance — nafta • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Evaluate parent kinetics using the NAFTA guidance — nafta" /> -<meta property="og:description" content="The function fits the SFO, IORE and DFOP models using mmkin +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Evaluate parent kinetics using the NAFTA guidance — nafta • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Evaluate parent kinetics using the NAFTA guidance — nafta"><meta property="og:description" content="The function fits the SFO, IORE and DFOP models using mmkin and returns an object of class nafta that has methods for printing and plotting. Print nafta objects. The results for the three models are printed in the -order of increasing model complexity, i.e. SFO, then IORE, and finally DFOP." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +order of increasing model complexity, i.e. SFO, then IORE, and finally DFOP."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -76,13 +21,12 @@ order of increasing model complexity, i.e. SFO, then IORE, and finally DFOP." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -91,8 +35,7 @@ order of increasing model complexity, i.e. SFO, then IORE, and finally DFOP." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -102,6 +45,9 @@ order of increasing model complexity, i.e. SFO, then IORE, and finally DFOP." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -116,174 +62,162 @@ order of increasing model complexity, i.e. SFO, then IORE, and finally DFOP." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Evaluate parent kinetics using the NAFTA guidance</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/nafta.R'><code>R/nafta.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/nafta.R" class="external-link"><code>R/nafta.R</code></a></small> <div class="hidden name"><code>nafta.Rd</code></div> </div> <div class="ref-description"> - <p>The function fits the SFO, IORE and DFOP models using <code><a href='mmkin.html'>mmkin</a></code> + <p>The function fits the SFO, IORE and DFOP models using <code><a href="mmkin.html">mmkin</a></code> and returns an object of class <code>nafta</code> that has methods for printing and plotting.</p> <p>Print nafta objects. The results for the three models are printed in the order of increasing model complexity, i.e. SFO, then IORE, and finally DFOP.</p> </div> - <pre class="usage"><span class='fu'>nafta</span><span class='op'>(</span><span class='va'>ds</span>, title <span class='op'>=</span> <span class='cn'>NA</span>, quiet <span class='op'>=</span> <span class='cn'>FALSE</span>, <span class='va'>...</span><span class='op'>)</span> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">nafta</span><span class="op">(</span><span class="va">ds</span>, title <span class="op">=</span> <span class="cn">NA</span>, quiet <span class="op">=</span> <span class="cn">FALSE</span>, <span class="va">...</span><span class="op">)</span> -<span class='co'># S3 method for nafta</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>x</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, digits <span class='op'>=</span> <span class='fl'>3</span>, <span class='va'>...</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>ds</th> - <td><p>A dataframe that must contain one variable called "time" with the -time values specified by the <code>time</code> argument, one column called -"name" with the grouping of the observed values, and finally one column of -observed values called "value".</p></td> - </tr> - <tr> - <th>title</th> - <td><p>Optional title of the dataset</p></td> - </tr> - <tr> - <th>quiet</th> - <td><p>Should the evaluation text be shown?</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Further arguments passed to <code><a href='mmkin.html'>mmkin</a></code> (not for the -printing method).</p></td> - </tr> - <tr> - <th>x</th> - <td><p>An <code>nafta</code> object.</p></td> - </tr> - <tr> - <th>digits</th> - <td><p>Number of digits to be used for printing parameters and -dissipation times.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2> +<span class="co"># S3 method for nafta</span> +<span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">x</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, digits <span class="op">=</span> <span class="fl">3</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + <div id="source"> + <h2>Source</h2> <p>NAFTA (2011) Guidance for evaluating and calculating degradation kinetics in environmental media. NAFTA Technical Working Group on Pesticides -<a href='https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/guidance-evaluating-and-calculating-degradation'>https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/guidance-evaluating-and-calculating-degradation</a> +<a href="https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/guidance-evaluating-and-calculating-degradation" class="external-link">https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/guidance-evaluating-and-calculating-degradation</a> accessed 2019-02-22</p> <p>US EPA (2015) Standard Operating Procedure for Using the NAFTA Guidance to Calculate Representative Half-life Values and Characterizing Pesticide Degradation -<a href='https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/standard-operating-procedure-using-nafta-guidance'>https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/standard-operating-procedure-using-nafta-guidance</a></p> - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - +<a href="https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/standard-operating-procedure-using-nafta-guidance" class="external-link">https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/standard-operating-procedure-using-nafta-guidance</a></p> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>ds</dt> +<dd><p>A dataframe that must contain one variable called "time" with the +time values specified by the <code>time</code> argument, one column called +"name" with the grouping of the observed values, and finally one column of +observed values called "value".</p></dd> +<dt>title</dt> +<dd><p>Optional title of the dataset</p></dd> +<dt>quiet</dt> +<dd><p>Should the evaluation text be shown?</p></dd> +<dt>...</dt> +<dd><p>Further arguments passed to <code><a href="mmkin.html">mmkin</a></code> (not for the +printing method).</p></dd> +<dt>x</dt> +<dd><p>An <code>nafta</code> object.</p></dd> +<dt>digits</dt> +<dd><p>Number of digits to be used for printing parameters and +dissipation times.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>An list of class <code>nafta</code>. The list element named "mmkin" is the -<code><a href='mmkin.html'>mmkin</a></code> object containing the fits of the three models. The +<code><a href="mmkin.html">mmkin</a></code> object containing the fits of the three models. The list element named "title" contains the title of the dataset used. The list element "data" contains the dataset used in the fits.</p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> - <span class='va'>nafta_evaluation</span> <span class='op'><-</span> <span class='fu'>nafta</span><span class='op'>(</span><span class='va'>NAFTA_SOP_Appendix_D</span>, cores <span class='op'>=</span> <span class='fl'>1</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>The SFO model is rejected as S_SFO is equal or higher than the critical value S_c</span></div><div class='output co'>#> <span class='message'>The representative half-life of the IORE model is longer than the one corresponding</span></div><div class='output co'>#> <span class='message'>to the terminal degradation rate found with the DFOP model.</span></div><div class='output co'>#> <span class='message'>The representative half-life obtained from the DFOP model may be used</span></div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>nafta_evaluation</span><span class='op'>)</span> -</div><div class='output co'>#> Sums of squares: -#> SFO IORE DFOP -#> 1378.6832 615.7730 517.8836 -#> -#> Critical sum of squares for checking the SFO model: -#> [1] 717.4598 -#> -#> Parameters: -#> $SFO -#> Estimate Pr(>t) Lower Upper -#> parent_0 83.7558 1.80e-14 77.18268 90.3288 -#> k_parent 0.0017 7.43e-05 0.00112 0.0026 -#> sigma 8.7518 1.22e-05 5.64278 11.8608 -#> -#> $IORE -#> Estimate Pr(>t) Lower Upper -#> parent_0 9.69e+01 NA 8.88e+01 1.05e+02 -#> k__iore_parent 8.40e-14 NA 1.79e-18 3.94e-09 -#> N_parent 6.68e+00 NA 4.19e+00 9.17e+00 -#> sigma 5.85e+00 NA 3.76e+00 7.94e+00 -#> -#> $DFOP -#> Estimate Pr(>t) Lower Upper -#> parent_0 9.76e+01 1.94e-13 9.02e+01 1.05e+02 -#> k1 4.24e-02 5.92e-03 2.03e-02 8.88e-02 -#> k2 8.24e-04 6.48e-03 3.89e-04 1.75e-03 -#> g 2.88e-01 2.47e-05 1.95e-01 4.03e-01 -#> sigma 5.36e+00 2.22e-05 3.43e+00 7.30e+00 -#> -#> -#> DTx values: -#> DT50 DT90 DT50_rep -#> SFO 407 1350 407 -#> IORE 541 5190000 1560000 -#> DFOP 429 2380 841 -#> -#> Representative half-life: -#> [1] 841.41</div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>nafta_evaluation</span><span class='op'>)</span> -</div><div class='img'><img src='nafta-1.png' alt='' width='700' height='433' /></div><div class='input'> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"> <span class="va">nafta_evaluation</span> <span class="op"><-</span> <span class="fu">nafta</span><span class="op">(</span><span class="va">NAFTA_SOP_Appendix_D</span>, cores <span class="op">=</span> <span class="fl">1</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> The SFO model is rejected as S_SFO is equal or higher than the critical value S_c</span> +<span class="r-msg co"><span class="r-pr">#></span> The representative half-life of the IORE model is longer than the one corresponding</span> +<span class="r-msg co"><span class="r-pr">#></span> to the terminal degradation rate found with the DFOP model.</span> +<span class="r-msg co"><span class="r-pr">#></span> The representative half-life obtained from the DFOP model may be used</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">nafta_evaluation</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Sums of squares:</span> +<span class="r-out co"><span class="r-pr">#></span> SFO IORE DFOP </span> +<span class="r-out co"><span class="r-pr">#></span> 1378.6832 615.7730 517.8836 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Critical sum of squares for checking the SFO model:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] 717.4598</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> $SFO</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 83.7558 1.80e-14 77.18268 90.3288</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.0017 7.43e-05 0.00112 0.0026</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 8.7518 1.22e-05 5.64278 11.8608</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $IORE</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 9.69e+01 NA 8.88e+01 1.05e+02</span> +<span class="r-out co"><span class="r-pr">#></span> k__iore_parent 8.40e-14 NA 1.79e-18 3.94e-09</span> +<span class="r-out co"><span class="r-pr">#></span> N_parent 6.68e+00 NA 4.19e+00 9.17e+00</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 5.85e+00 NA 3.76e+00 7.94e+00</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $DFOP</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 9.76e+01 1.94e-13 9.02e+01 1.05e+02</span> +<span class="r-out co"><span class="r-pr">#></span> k1 4.24e-02 5.92e-03 2.03e-02 8.88e-02</span> +<span class="r-out co"><span class="r-pr">#></span> k2 8.24e-04 6.48e-03 3.89e-04 1.75e-03</span> +<span class="r-out co"><span class="r-pr">#></span> g 2.88e-01 2.47e-05 1.95e-01 4.03e-01</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 5.36e+00 2.22e-05 3.43e+00 7.30e+00</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> DTx values:</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90 DT50_rep</span> +<span class="r-out co"><span class="r-pr">#></span> SFO 407 1350 407</span> +<span class="r-out co"><span class="r-pr">#></span> IORE 541 5190000 1560000</span> +<span class="r-out co"><span class="r-pr">#></span> DFOP 429 2380 841</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Representative half-life:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] 841.41</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">nafta_evaluation</span><span class="op">)</span></span> +<span class="r-plt img"><img src="nafta-1.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/nlme-1.png b/docs/reference/nlme-1.png Binary files differindex 365aaef0..67cc7f3c 100644 --- a/docs/reference/nlme-1.png +++ b/docs/reference/nlme-1.png diff --git a/docs/reference/nlme-2.png b/docs/reference/nlme-2.png Binary files differindex 40841404..bb1e6f81 100644 --- a/docs/reference/nlme-2.png +++ b/docs/reference/nlme-2.png diff --git a/docs/reference/nlme.html b/docs/reference/nlme.html index 6821bacf..5eebecaa 100644 --- a/docs/reference/nlme.html +++ b/docs/reference/nlme.html @@ -1,70 +1,15 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Helper functions to create nlme models from mmkin row objects — nlme_function • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Helper functions to create nlme models from mmkin row objects — nlme_function" /> -<meta property="og:description" content="These functions facilitate setting up a nonlinear mixed effects model for +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Helper functions to create nlme models from mmkin row objects — nlme_function • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Helper functions to create nlme models from mmkin row objects — nlme_function"><meta property="og:description" content="These functions facilitate setting up a nonlinear mixed effects model for an mmkin row object. An mmkin row object is essentially a list of mkinfit objects that have been obtained by fitting the same model to a list of -datasets. They are used internally by the nlme.mmkin() method." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +datasets. They are used internally by the nlme.mmkin() method."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -75,13 +20,12 @@ datasets. They are used internally by the nlme.mmkin() method." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.5</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -90,8 +34,7 @@ datasets. They are used internally by the nlme.mmkin() method." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -101,6 +44,9 @@ datasets. They are used internally by the nlme.mmkin() method." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -115,34 +61,27 @@ datasets. They are used internally by the nlme.mmkin() method." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Helper functions to create nlme models from mmkin row objects</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/nlme.R'><code>R/nlme.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/nlme.R" class="external-link"><code>R/nlme.R</code></a></small> <div class="hidden name"><code>nlme.Rd</code></div> </div> @@ -150,137 +89,128 @@ datasets. They are used internally by the nlme.mmkin() method." /> <p>These functions facilitate setting up a nonlinear mixed effects model for an mmkin row object. An mmkin row object is essentially a list of mkinfit objects that have been obtained by fitting the same model to a list of -datasets. They are used internally by the <code><a href='nlme.mmkin.html'>nlme.mmkin()</a></code> method.</p> +datasets. They are used internally by the <code><a href="nlme.mmkin.html">nlme.mmkin()</a></code> method.</p> </div> - <pre class="usage"><span class='fu'>nlme_function</span><span class='op'>(</span><span class='va'>object</span><span class='op'>)</span> - -<span class='fu'>mean_degparms</span><span class='op'>(</span><span class='va'>object</span>, random <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span> - -<span class='fu'>nlme_data</span><span class='op'>(</span><span class='va'>object</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>An mmkin row object containing several fits of the same model to different datasets</p></td> - </tr> - <tr> - <th>random</th> - <td><p>Should a list with fixed and random effects be returned?</p></td> - </tr> - </table> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">nlme_function</span><span class="op">(</span><span class="va">object</span><span class="op">)</span> - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - - <p>A function that can be used with nlme</p> -<p>If random is FALSE (default), a named vector containing mean values -of the fitted degradation model parameters. If random is TRUE, a list with -fixed and random effects, in the format required by the start argument of -nlme for the case of a single grouping variable ds.</p> -<p>A <code><a href='https://rdrr.io/pkg/nlme/man/groupedData.html'>groupedData</a></code> object</p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p><code><a href='nlme.mmkin.html'>nlme.mmkin</a></code></p></div> - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='va'>sampling_times</span> <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>1</span>, <span class='fl'>3</span>, <span class='fl'>7</span>, <span class='fl'>14</span>, <span class='fl'>28</span>, <span class='fl'>60</span>, <span class='fl'>90</span>, <span class='fl'>120</span><span class='op'>)</span> -<span class='va'>m_SFO</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span> -<span class='va'>d_SFO_1</span> <span class='op'><-</span> <span class='fu'><a href='mkinpredict.html'>mkinpredict</a></span><span class='op'>(</span><span class='va'>m_SFO</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_parent <span class='op'>=</span> <span class='fl'>0.1</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>98</span><span class='op'>)</span>, <span class='va'>sampling_times</span><span class='op'>)</span> -<span class='va'>d_SFO_1_long</span> <span class='op'><-</span> <span class='fu'><a href='mkin_wide_to_long.html'>mkin_wide_to_long</a></span><span class='op'>(</span><span class='va'>d_SFO_1</span>, time <span class='op'>=</span> <span class='st'>"time"</span><span class='op'>)</span> -<span class='va'>d_SFO_2</span> <span class='op'><-</span> <span class='fu'><a href='mkinpredict.html'>mkinpredict</a></span><span class='op'>(</span><span class='va'>m_SFO</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_parent <span class='op'>=</span> <span class='fl'>0.05</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>102</span><span class='op'>)</span>, <span class='va'>sampling_times</span><span class='op'>)</span> -<span class='va'>d_SFO_2_long</span> <span class='op'><-</span> <span class='fu'><a href='mkin_wide_to_long.html'>mkin_wide_to_long</a></span><span class='op'>(</span><span class='va'>d_SFO_2</span>, time <span class='op'>=</span> <span class='st'>"time"</span><span class='op'>)</span> -<span class='va'>d_SFO_3</span> <span class='op'><-</span> <span class='fu'><a href='mkinpredict.html'>mkinpredict</a></span><span class='op'>(</span><span class='va'>m_SFO</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_parent <span class='op'>=</span> <span class='fl'>0.02</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>103</span><span class='op'>)</span>, <span class='va'>sampling_times</span><span class='op'>)</span> -<span class='va'>d_SFO_3_long</span> <span class='op'><-</span> <span class='fu'><a href='mkin_wide_to_long.html'>mkin_wide_to_long</a></span><span class='op'>(</span><span class='va'>d_SFO_3</span>, time <span class='op'>=</span> <span class='st'>"time"</span><span class='op'>)</span> - -<span class='va'>d1</span> <span class='op'><-</span> <span class='fu'><a href='add_err.html'>add_err</a></span><span class='op'>(</span><span class='va'>d_SFO_1</span>, <span class='kw'>function</span><span class='op'>(</span><span class='va'>value</span><span class='op'>)</span> <span class='fl'>3</span>, n <span class='op'>=</span> <span class='fl'>1</span><span class='op'>)</span> -<span class='va'>d2</span> <span class='op'><-</span> <span class='fu'><a href='add_err.html'>add_err</a></span><span class='op'>(</span><span class='va'>d_SFO_2</span>, <span class='kw'>function</span><span class='op'>(</span><span class='va'>value</span><span class='op'>)</span> <span class='fl'>2</span>, n <span class='op'>=</span> <span class='fl'>1</span><span class='op'>)</span> -<span class='va'>d3</span> <span class='op'><-</span> <span class='fu'><a href='add_err.html'>add_err</a></span><span class='op'>(</span><span class='va'>d_SFO_3</span>, <span class='kw'>function</span><span class='op'>(</span><span class='va'>value</span><span class='op'>)</span> <span class='fl'>4</span>, n <span class='op'>=</span> <span class='fl'>1</span><span class='op'>)</span> -<span class='va'>ds</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>d1 <span class='op'>=</span> <span class='va'>d1</span>, d2 <span class='op'>=</span> <span class='va'>d2</span>, d3 <span class='op'>=</span> <span class='va'>d3</span><span class='op'>)</span> +<span class="fu">nlme_data</span><span class="op">(</span><span class="va">object</span><span class="op">)</span></code></pre></div> + </div> -<span class='va'>f</span> <span class='op'><-</span> <span class='fu'><a href='mmkin.html'>mmkin</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='va'>ds</span>, cores <span class='op'>=</span> <span class='fl'>1</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='va'>mean_dp</span> <span class='op'><-</span> <span class='fu'>mean_degparms</span><span class='op'>(</span><span class='va'>f</span><span class='op'>)</span> -<span class='va'>grouped_data</span> <span class='op'><-</span> <span class='fu'>nlme_data</span><span class='op'>(</span><span class='va'>f</span><span class='op'>)</span> -<span class='va'>nlme_f</span> <span class='op'><-</span> <span class='fu'>nlme_function</span><span class='op'>(</span><span class='va'>f</span><span class='op'>)</span> -<span class='co'># These assignments are necessary for these objects to be</span> -<span class='co'># visible to nlme and augPred when evaluation is done by</span> -<span class='co'># pkgdown to generated the html docs.</span> -<span class='fu'><a href='https://rdrr.io/r/base/assign.html'>assign</a></span><span class='op'>(</span><span class='st'>"nlme_f"</span>, <span class='va'>nlme_f</span>, <span class='fu'><a href='https://rdrr.io/r/base/environment.html'>globalenv</a></span><span class='op'>(</span><span class='op'>)</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/assign.html'>assign</a></span><span class='op'>(</span><span class='st'>"grouped_data"</span>, <span class='va'>grouped_data</span>, <span class='fu'><a href='https://rdrr.io/r/base/environment.html'>globalenv</a></span><span class='op'>(</span><span class='op'>)</span><span class='op'>)</span> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>An mmkin row object containing several fits of the same model to different datasets</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>A function that can be used with nlme +A <code><a href="https://rdrr.io/pkg/nlme/man/groupedData.html" class="external-link">groupedData</a></code> object</p> + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p><code><a href="nlme.mmkin.html">nlme.mmkin</a></code></p></div> + </div> -<span class='kw'><a href='https://rdrr.io/r/base/library.html'>library</a></span><span class='op'>(</span><span class='va'><a href='https://svn.r-project.org/R-packages/trunk/nlme/'>nlme</a></span><span class='op'>)</span> -<span class='va'>m_nlme</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme</a></span><span class='op'>(</span><span class='va'>value</span> <span class='op'>~</span> <span class='fu'>nlme_f</span><span class='op'>(</span><span class='va'>name</span>, <span class='va'>time</span>, <span class='va'>parent_0</span>, <span class='va'>log_k_parent_sink</span><span class='op'>)</span>, - data <span class='op'>=</span> <span class='va'>grouped_data</span>, - fixed <span class='op'>=</span> <span class='va'>parent_0</span> <span class='op'>+</span> <span class='va'>log_k_parent_sink</span> <span class='op'>~</span> <span class='fl'>1</span>, - random <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/pkg/nlme/man/pdDiag.html'>pdDiag</a></span><span class='op'>(</span><span class='va'>parent_0</span> <span class='op'>+</span> <span class='va'>log_k_parent_sink</span> <span class='op'>~</span> <span class='fl'>1</span><span class='op'>)</span>, - start <span class='op'>=</span> <span class='va'>mean_dp</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>m_nlme</span><span class='op'>)</span> -</div><div class='output co'>#> Nonlinear mixed-effects model fit by maximum likelihood -#> Model: value ~ nlme_f(name, time, parent_0, log_k_parent_sink) -#> Data: grouped_data -#> AIC BIC logLik -#> 300.6824 310.2426 -145.3412 -#> -#> Random effects: -#> Formula: list(parent_0 ~ 1, log_k_parent_sink ~ 1) -#> Level: ds -#> Structure: Diagonal -#> parent_0 log_k_parent_sink Residual -#> StdDev: 1.697361 0.6801209 3.666073 -#> -#> Fixed effects: parent_0 + log_k_parent_sink ~ 1 -#> Value Std.Error DF t-value p-value -#> parent_0 100.99378 1.3890416 46 72.70753 0 -#> log_k_parent_sink -3.07521 0.4018589 46 -7.65246 0 -#> Correlation: -#> prnt_0 -#> log_k_parent_sink 0.027 -#> -#> Standardized Within-Group Residuals: -#> Min Q1 Med Q3 Max -#> -1.9942823 -0.5622565 0.1791579 0.7165038 2.0704781 -#> -#> Number of Observations: 50 -#> Number of Groups: 3 </div><div class='input'><span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/pkg/nlme/man/augPred.html'>augPred</a></span><span class='op'>(</span><span class='va'>m_nlme</span>, level <span class='op'>=</span> <span class='fl'>0</span><span class='op'>:</span><span class='fl'>1</span><span class='op'>)</span>, layout <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>3</span>, <span class='fl'>1</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='img'><img src='nlme-1.png' alt='' width='700' height='433' /></div><div class='input'><span class='co'># augPred does not work on fits with more than one state</span> -<span class='co'># variable</span> -<span class='co'>#</span> -<span class='co'># The procedure is greatly simplified by the nlme.mmkin function</span> -<span class='va'>f_nlme</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme</a></span><span class='op'>(</span><span class='va'>f</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>f_nlme</span><span class='op'>)</span> -</div><div class='img'><img src='nlme-2.png' alt='' width='700' height='433' /></div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="va">sampling_times</span> <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">1</span>, <span class="fl">3</span>, <span class="fl">7</span>, <span class="fl">14</span>, <span class="fl">28</span>, <span class="fl">60</span>, <span class="fl">90</span>, <span class="fl">120</span><span class="op">)</span></span> +<span class="r-in"><span class="va">m_SFO</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="va">d_SFO_1</span> <span class="op"><-</span> <span class="fu"><a href="mkinpredict.html">mkinpredict</a></span><span class="op">(</span><span class="va">m_SFO</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_parent <span class="op">=</span> <span class="fl">0.1</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">98</span><span class="op">)</span>, <span class="va">sampling_times</span><span class="op">)</span></span> +<span class="r-in"><span class="va">d_SFO_1_long</span> <span class="op"><-</span> <span class="fu"><a href="mkin_wide_to_long.html">mkin_wide_to_long</a></span><span class="op">(</span><span class="va">d_SFO_1</span>, time <span class="op">=</span> <span class="st">"time"</span><span class="op">)</span></span> +<span class="r-in"><span class="va">d_SFO_2</span> <span class="op"><-</span> <span class="fu"><a href="mkinpredict.html">mkinpredict</a></span><span class="op">(</span><span class="va">m_SFO</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_parent <span class="op">=</span> <span class="fl">0.05</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">102</span><span class="op">)</span>, <span class="va">sampling_times</span><span class="op">)</span></span> +<span class="r-in"><span class="va">d_SFO_2_long</span> <span class="op"><-</span> <span class="fu"><a href="mkin_wide_to_long.html">mkin_wide_to_long</a></span><span class="op">(</span><span class="va">d_SFO_2</span>, time <span class="op">=</span> <span class="st">"time"</span><span class="op">)</span></span> +<span class="r-in"><span class="va">d_SFO_3</span> <span class="op"><-</span> <span class="fu"><a href="mkinpredict.html">mkinpredict</a></span><span class="op">(</span><span class="va">m_SFO</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_parent <span class="op">=</span> <span class="fl">0.02</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">103</span><span class="op">)</span>, <span class="va">sampling_times</span><span class="op">)</span></span> +<span class="r-in"><span class="va">d_SFO_3_long</span> <span class="op"><-</span> <span class="fu"><a href="mkin_wide_to_long.html">mkin_wide_to_long</a></span><span class="op">(</span><span class="va">d_SFO_3</span>, time <span class="op">=</span> <span class="st">"time"</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">d1</span> <span class="op"><-</span> <span class="fu"><a href="add_err.html">add_err</a></span><span class="op">(</span><span class="va">d_SFO_1</span>, <span class="kw">function</span><span class="op">(</span><span class="va">value</span><span class="op">)</span> <span class="fl">3</span>, n <span class="op">=</span> <span class="fl">1</span><span class="op">)</span></span> +<span class="r-in"><span class="va">d2</span> <span class="op"><-</span> <span class="fu"><a href="add_err.html">add_err</a></span><span class="op">(</span><span class="va">d_SFO_2</span>, <span class="kw">function</span><span class="op">(</span><span class="va">value</span><span class="op">)</span> <span class="fl">2</span>, n <span class="op">=</span> <span class="fl">1</span><span class="op">)</span></span> +<span class="r-in"><span class="va">d3</span> <span class="op"><-</span> <span class="fu"><a href="add_err.html">add_err</a></span><span class="op">(</span><span class="va">d_SFO_3</span>, <span class="kw">function</span><span class="op">(</span><span class="va">value</span><span class="op">)</span> <span class="fl">4</span>, n <span class="op">=</span> <span class="fl">1</span><span class="op">)</span></span> +<span class="r-in"><span class="va">ds</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>d1 <span class="op">=</span> <span class="va">d1</span>, d2 <span class="op">=</span> <span class="va">d2</span>, d3 <span class="op">=</span> <span class="va">d3</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">f</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="va">ds</span>, cores <span class="op">=</span> <span class="fl">1</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">mean_dp</span> <span class="op"><-</span> <span class="fu"><a href="mean_degparms.html">mean_degparms</a></span><span class="op">(</span><span class="va">f</span><span class="op">)</span></span> +<span class="r-in"><span class="va">grouped_data</span> <span class="op"><-</span> <span class="fu">nlme_data</span><span class="op">(</span><span class="va">f</span><span class="op">)</span></span> +<span class="r-in"><span class="va">nlme_f</span> <span class="op"><-</span> <span class="fu">nlme_function</span><span class="op">(</span><span class="va">f</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># These assignments are necessary for these objects to be</span></span> +<span class="r-in"><span class="co"># visible to nlme and augPred when evaluation is done by</span></span> +<span class="r-in"><span class="co"># pkgdown to generate the html docs.</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/assign.html" class="external-link">assign</a></span><span class="op">(</span><span class="st">"nlme_f"</span>, <span class="va">nlme_f</span>, <span class="fu"><a href="https://rdrr.io/r/base/environment.html" class="external-link">globalenv</a></span><span class="op">(</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/assign.html" class="external-link">assign</a></span><span class="op">(</span><span class="st">"grouped_data"</span>, <span class="va">grouped_data</span>, <span class="fu"><a href="https://rdrr.io/r/base/environment.html" class="external-link">globalenv</a></span><span class="op">(</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="kw"><a href="https://rdrr.io/r/base/library.html" class="external-link">library</a></span><span class="op">(</span><span class="va"><a href="https://svn.r-project.org/R-packages/trunk/nlme/" class="external-link">nlme</a></span><span class="op">)</span></span> +<span class="r-in"><span class="va">m_nlme</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></span><span class="op">(</span><span class="va">value</span> <span class="op">~</span> <span class="fu">nlme_f</span><span class="op">(</span><span class="va">name</span>, <span class="va">time</span>, <span class="va">parent_0</span>, <span class="va">log_k_parent_sink</span><span class="op">)</span>,</span> +<span class="r-in"> data <span class="op">=</span> <span class="va">grouped_data</span>,</span> +<span class="r-in"> fixed <span class="op">=</span> <span class="va">parent_0</span> <span class="op">+</span> <span class="va">log_k_parent_sink</span> <span class="op">~</span> <span class="fl">1</span>,</span> +<span class="r-in"> random <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/pkg/nlme/man/pdDiag.html" class="external-link">pdDiag</a></span><span class="op">(</span><span class="va">parent_0</span> <span class="op">+</span> <span class="va">log_k_parent_sink</span> <span class="op">~</span> <span class="fl">1</span><span class="op">)</span>,</span> +<span class="r-in"> start <span class="op">=</span> <span class="va">mean_dp</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/summary.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">m_nlme</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Nonlinear mixed-effects model fit by maximum likelihood</span> +<span class="r-out co"><span class="r-pr">#></span> Model: value ~ nlme_f(name, time, parent_0, log_k_parent_sink) </span> +<span class="r-out co"><span class="r-pr">#></span> Data: grouped_data </span> +<span class="r-out co"><span class="r-pr">#></span> AIC BIC logLik</span> +<span class="r-out co"><span class="r-pr">#></span> 300.6824 310.2426 -145.3412</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Random effects:</span> +<span class="r-out co"><span class="r-pr">#></span> Formula: list(parent_0 ~ 1, log_k_parent_sink ~ 1)</span> +<span class="r-out co"><span class="r-pr">#></span> Level: ds</span> +<span class="r-out co"><span class="r-pr">#></span> Structure: Diagonal</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_k_parent_sink Residual</span> +<span class="r-out co"><span class="r-pr">#></span> StdDev: 1.697361 0.6801209 3.666073</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fixed effects: parent_0 + log_k_parent_sink ~ 1 </span> +<span class="r-out co"><span class="r-pr">#></span> Value Std.Error DF t-value p-value</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 100.99378 1.3890416 46 72.70753 0</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent_sink -3.07521 0.4018589 46 -7.65246 0</span> +<span class="r-out co"><span class="r-pr">#></span> Correlation: </span> +<span class="r-out co"><span class="r-pr">#></span> prnt_0</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent_sink 0.027 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Standardized Within-Group Residuals:</span> +<span class="r-out co"><span class="r-pr">#></span> Min Q1 Med Q3 Max </span> +<span class="r-out co"><span class="r-pr">#></span> -1.9942823 -0.5622565 0.1791579 0.7165038 2.0704781 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Number of Observations: 50</span> +<span class="r-out co"><span class="r-pr">#></span> Number of Groups: 3 </span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/pkg/nlme/man/augPred.html" class="external-link">augPred</a></span><span class="op">(</span><span class="va">m_nlme</span>, level <span class="op">=</span> <span class="fl">0</span><span class="op">:</span><span class="fl">1</span><span class="op">)</span>, layout <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">3</span>, <span class="fl">1</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-plt img"><img src="nlme-1.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="co"># augPred does not work on fits with more than one state</span></span> +<span class="r-in"><span class="co"># variable</span></span> +<span class="r-in"><span class="co">#</span></span> +<span class="r-in"><span class="co"># The procedure is greatly simplified by the nlme.mmkin function</span></span> +<span class="r-in"><span class="va">f_nlme</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></span><span class="op">(</span><span class="va">f</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_nlme</span><span class="op">)</span></span> +<span class="r-plt img"><img src="nlme-2.png" alt="" width="700" height="433"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/nlme.mmkin-1.png b/docs/reference/nlme.mmkin-1.png Binary files differindex 95adfafb..d93b0950 100644 --- a/docs/reference/nlme.mmkin-1.png +++ b/docs/reference/nlme.mmkin-1.png diff --git a/docs/reference/nlme.mmkin-2.png b/docs/reference/nlme.mmkin-2.png Binary files differindex 53b6fc76..5afccfbb 100644 --- a/docs/reference/nlme.mmkin-2.png +++ b/docs/reference/nlme.mmkin-2.png diff --git a/docs/reference/nlme.mmkin-3.png b/docs/reference/nlme.mmkin-3.png Binary files differindex e87d15e5..bf3aac6c 100644 --- a/docs/reference/nlme.mmkin-3.png +++ b/docs/reference/nlme.mmkin-3.png diff --git a/docs/reference/nlme.mmkin.html b/docs/reference/nlme.mmkin.html index b3052605..56770856 100644 --- a/docs/reference/nlme.mmkin.html +++ b/docs/reference/nlme.mmkin.html @@ -1,69 +1,14 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Create an nlme model for an mmkin row object — nlme.mmkin • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Create an nlme model for an mmkin row object — nlme.mmkin" /> -<meta property="og:description" content="This functions sets up a nonlinear mixed effects model for an mmkin row +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Create an nlme model for an mmkin row object — nlme.mmkin • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Create an nlme model for an mmkin row object — nlme.mmkin"><meta property="og:description" content="This functions sets up a nonlinear mixed effects model for an mmkin row object. An mmkin row object is essentially a list of mkinfit objects that -have been obtained by fitting the same model to a list of datasets." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +have been obtained by fitting the same model to a list of datasets."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -74,13 +19,12 @@ have been obtained by fitting the same model to a list of datasets." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.5</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -89,8 +33,7 @@ have been obtained by fitting the same model to a list of datasets." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -100,6 +43,9 @@ have been obtained by fitting the same model to a list of datasets." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -114,34 +60,27 @@ have been obtained by fitting the same model to a list of datasets." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Create an nlme model for an mmkin row object</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/nlme.mmkin.R'><code>R/nlme.mmkin.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/nlme.mmkin.R" class="external-link"><code>R/nlme.mmkin.R</code></a></small> <div class="hidden name"><code>nlme.mmkin.Rd</code></div> </div> @@ -151,339 +90,316 @@ object. An mmkin row object is essentially a list of mkinfit objects that have been obtained by fitting the same model to a list of datasets.</p> </div> - <pre class="usage"><span class='co'># S3 method for mmkin</span> -<span class='fu'><a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme</a></span><span class='op'>(</span> - <span class='va'>model</span>, - data <span class='op'>=</span> <span class='st'>"auto"</span>, - fixed <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/lapply.html'>lapply</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/list.html'>as.list</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/names.html'>names</a></span><span class='op'>(</span><span class='fu'><a href='nlme_function.html'>mean_degparms</a></span><span class='op'>(</span><span class='va'>model</span><span class='op'>)</span><span class='op'>)</span><span class='op'>)</span>, <span class='kw'>function</span><span class='op'>(</span><span class='va'>el</span><span class='op'>)</span> <span class='fu'><a href='https://rdrr.io/r/base/eval.html'>eval</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/parse.html'>parse</a></span><span class='op'>(</span>text <span class='op'>=</span> - <span class='fu'><a href='https://rdrr.io/r/base/paste.html'>paste</a></span><span class='op'>(</span><span class='va'>el</span>, <span class='fl'>1</span>, sep <span class='op'>=</span> <span class='st'>"~"</span><span class='op'>)</span><span class='op'>)</span><span class='op'>)</span><span class='op'>)</span>, - random <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/pkg/nlme/man/pdDiag.html'>pdDiag</a></span><span class='op'>(</span><span class='va'>fixed</span><span class='op'>)</span>, - <span class='va'>groups</span>, - start <span class='op'>=</span> <span class='fu'><a href='nlme_function.html'>mean_degparms</a></span><span class='op'>(</span><span class='va'>model</span>, random <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span>, - correlation <span class='op'>=</span> <span class='cn'>NULL</span>, - weights <span class='op'>=</span> <span class='cn'>NULL</span>, - <span class='va'>subset</span>, - method <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"ML"</span>, <span class='st'>"REML"</span><span class='op'>)</span>, - na.action <span class='op'>=</span> <span class='va'>na.fail</span>, - <span class='va'>naPattern</span>, - control <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span><span class='op'>)</span>, - verbose <span class='op'>=</span> <span class='cn'>FALSE</span> -<span class='op'>)</span> - -<span class='co'># S3 method for nlme.mmkin</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>x</span>, digits <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/Extremes.html'>max</a></span><span class='op'>(</span><span class='fl'>3</span>, <span class='fu'><a href='https://rdrr.io/r/base/options.html'>getOption</a></span><span class='op'>(</span><span class='st'>"digits"</span><span class='op'>)</span> <span class='op'>-</span> <span class='fl'>3</span><span class='op'>)</span>, <span class='va'>...</span><span class='op'>)</span> - -<span class='co'># S3 method for nlme.mmkin</span> -<span class='fu'><a href='https://rdrr.io/r/stats/update.html'>update</a></span><span class='op'>(</span><span class='va'>object</span>, <span class='va'>...</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>model</th> - <td><p>An <a href='mmkin.html'>mmkin</a> row object.</p></td> - </tr> - <tr> - <th>data</th> - <td><p>Ignored, data are taken from the mmkin model</p></td> - </tr> - <tr> - <th>fixed</th> - <td><p>Ignored, all degradation parameters fitted in the -mmkin model are used as fixed parameters</p></td> - </tr> - <tr> - <th>random</th> - <td><p>If not specified, correlated random effects are set up -for all optimised degradation model parameters using the log-Cholesky -parameterization <a href='https://rdrr.io/pkg/nlme/man/pdLogChol.html'>nlme::pdLogChol</a> that is also the default of -the generic <a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme</a> method.</p></td> - </tr> - <tr> - <th>groups</th> - <td><p>See the documentation of nlme</p></td> - </tr> - <tr> - <th>start</th> - <td><p>If not specified, mean values of the fitted degradation -parameters taken from the mmkin object are used</p></td> - </tr> - <tr> - <th>correlation</th> - <td><p>See the documentation of nlme</p></td> - </tr> - <tr> - <th>weights</th> - <td><p>passed to nlme</p></td> - </tr> - <tr> - <th>subset</th> - <td><p>passed to nlme</p></td> - </tr> - <tr> - <th>method</th> - <td><p>passed to nlme</p></td> - </tr> - <tr> - <th>na.action</th> - <td><p>passed to nlme</p></td> - </tr> - <tr> - <th>naPattern</th> - <td><p>passed to nlme</p></td> - </tr> - <tr> - <th>control</th> - <td><p>passed to nlme</p></td> - </tr> - <tr> - <th>verbose</th> - <td><p>passed to nlme</p></td> - </tr> - <tr> - <th>x</th> - <td><p>An nlme.mmkin object to print</p></td> - </tr> - <tr> - <th>digits</th> - <td><p>Number of digits to use for printing</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Update specifications passed to update.nlme</p></td> - </tr> - <tr> - <th>object</th> - <td><p>An nlme.mmkin object to update</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for mmkin</span> +<span class="fu"><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></span><span class="op">(</span> + <span class="va">model</span>, + data <span class="op">=</span> <span class="st">"auto"</span>, + fixed <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">as.list</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="fu"><a href="mean_degparms.html">mean_degparms</a></span><span class="op">(</span><span class="va">model</span><span class="op">)</span><span class="op">)</span><span class="op">)</span>, <span class="kw">function</span><span class="op">(</span><span class="va">el</span><span class="op">)</span> <span class="fu"><a href="https://rdrr.io/r/base/eval.html" class="external-link">eval</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/parse.html" class="external-link">parse</a></span><span class="op">(</span>text <span class="op">=</span> + <span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste</a></span><span class="op">(</span><span class="va">el</span>, <span class="fl">1</span>, sep <span class="op">=</span> <span class="st">"~"</span><span class="op">)</span><span class="op">)</span><span class="op">)</span><span class="op">)</span>, + random <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/pkg/nlme/man/pdDiag.html" class="external-link">pdDiag</a></span><span class="op">(</span><span class="va">fixed</span><span class="op">)</span>, + <span class="va">groups</span>, + start <span class="op">=</span> <span class="fu"><a href="mean_degparms.html">mean_degparms</a></span><span class="op">(</span><span class="va">model</span>, random <span class="op">=</span> <span class="cn">TRUE</span>, test_log_parms <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span>, + correlation <span class="op">=</span> <span class="cn">NULL</span>, + weights <span class="op">=</span> <span class="cn">NULL</span>, + <span class="va">subset</span>, + method <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"ML"</span>, <span class="st">"REML"</span><span class="op">)</span>, + na.action <span class="op">=</span> <span class="va">na.fail</span>, + <span class="va">naPattern</span>, + control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="op">)</span>, + verbose <span class="op">=</span> <span class="cn">FALSE</span> +<span class="op">)</span> + +<span class="co"># S3 method for nlme.mmkin</span> +<span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">x</span>, digits <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/Extremes.html" class="external-link">max</a></span><span class="op">(</span><span class="fl">3</span>, <span class="fu"><a href="https://rdrr.io/r/base/options.html" class="external-link">getOption</a></span><span class="op">(</span><span class="st">"digits"</span><span class="op">)</span> <span class="op">-</span> <span class="fl">3</span><span class="op">)</span>, <span class="va">...</span><span class="op">)</span> + +<span class="co"># S3 method for nlme.mmkin</span> +<span class="fu"><a href="https://rdrr.io/r/stats/update.html" class="external-link">update</a></span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>model</dt> +<dd><p>An <a href="mmkin.html">mmkin</a> row object.</p></dd> +<dt>data</dt> +<dd><p>Ignored, data are taken from the mmkin model</p></dd> +<dt>fixed</dt> +<dd><p>Ignored, all degradation parameters fitted in the +mmkin model are used as fixed parameters</p></dd> +<dt>random</dt> +<dd><p>If not specified, no correlations between random effects are +set up for the optimised degradation model parameters. This is +achieved by using the <a href="https://rdrr.io/pkg/nlme/man/pdDiag.html" class="external-link">nlme::pdDiag</a> method.</p></dd> +<dt>groups</dt> +<dd><p>See the documentation of nlme</p></dd> +<dt>start</dt> +<dd><p>If not specified, mean values of the fitted degradation +parameters taken from the mmkin object are used</p></dd> +<dt>correlation</dt> +<dd><p>See the documentation of nlme</p></dd> +<dt>weights</dt> +<dd><p>passed to nlme</p></dd> +<dt>subset</dt> +<dd><p>passed to nlme</p></dd> +<dt>method</dt> +<dd><p>passed to nlme</p></dd> +<dt>na.action</dt> +<dd><p>passed to nlme</p></dd> +<dt>naPattern</dt> +<dd><p>passed to nlme</p></dd> +<dt>control</dt> +<dd><p>passed to nlme</p></dd> +<dt>verbose</dt> +<dd><p>passed to nlme</p></dd> +<dt>x</dt> +<dd><p>An nlme.mmkin object to print</p></dd> +<dt>digits</dt> +<dd><p>Number of digits to use for printing</p></dd> +<dt>...</dt> +<dd><p>Update specifications passed to update.nlme</p></dd> +<dt>object</dt> +<dd><p>An nlme.mmkin object to update</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>Upon success, a fitted 'nlme.mmkin' object, which is an nlme object with additional elements. It also inherits from 'mixed.mmkin'.</p> - <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2> - + </div> + <div id="details"> + <h2>Details</h2> <p>Note that the convergence of the nlme algorithms depends on the quality of the data. In degradation kinetics, we often only have few datasets (e.g. data for few soils) and complicated degradation models, which may make it impossible to obtain convergence with nlme.</p> - <h2 class="hasAnchor" id="note"><a class="anchor" href="#note"></a>Note</h2> - - <p>As the object inherits from <a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme::nlme</a>, there is a wealth of + </div> + <div id="note"> + <h2>Note</h2> + <p>As the object inherits from <a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme::nlme</a>, there is a wealth of methods that will automatically work on 'nlme.mmkin' objects, such as -<code><a href='https://rdrr.io/pkg/nlme/man/intervals.html'>nlme::intervals()</a></code>, <code><a href='https://rdrr.io/pkg/nlme/man/anova.lme.html'>nlme::anova.lme()</a></code> and <code><a href='https://rdrr.io/pkg/nlme/man/coef.lme.html'>nlme::coef.lme()</a></code>.</p> - <h2 class="hasAnchor" id="see-also"><a class="anchor" href="#see-also"></a>See also</h2> - - <div class='dont-index'><p><code><a href='nlme_function.html'>nlme_function()</a></code>, <a href='plot.mixed.mmkin.html'>plot.mixed.mmkin</a>, <a href='summary.nlme.mmkin.html'>summary.nlme.mmkin</a></p></div> - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='va'>ds</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/lapply.html'>lapply</a></span><span class='op'>(</span><span class='va'>experimental_data_for_UBA_2019</span><span class='op'>[</span><span class='fl'>6</span><span class='op'>:</span><span class='fl'>10</span><span class='op'>]</span>, - <span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='fu'><a href='https://rdrr.io/r/base/subset.html'>subset</a></span><span class='op'>(</span><span class='va'>x</span><span class='op'>$</span><span class='va'>data</span><span class='op'>[</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"name"</span>, <span class='st'>"time"</span>, <span class='st'>"value"</span><span class='op'>)</span><span class='op'>]</span>, <span class='va'>name</span> <span class='op'>==</span> <span class='st'>"parent"</span><span class='op'>)</span><span class='op'>)</span> -<span class='va'>f</span> <span class='op'><-</span> <span class='fu'><a href='mmkin.html'>mmkin</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"DFOP"</span><span class='op'>)</span>, <span class='va'>ds</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, cores <span class='op'>=</span> <span class='fl'>1</span><span class='op'>)</span> -<span class='kw'><a href='https://rdrr.io/r/base/library.html'>library</a></span><span class='op'>(</span><span class='va'><a href='https://svn.r-project.org/R-packages/trunk/nlme/'>nlme</a></span><span class='op'>)</span> -<span class='va'>f_nlme_sfo</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme</a></span><span class='op'>(</span><span class='va'>f</span><span class='op'>[</span><span class='st'>"SFO"</span>, <span class='op'>]</span><span class='op'>)</span> - -<span class='co'># \dontrun{</span> - - <span class='va'>f_nlme_dfop</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme</a></span><span class='op'>(</span><span class='va'>f</span><span class='op'>[</span><span class='st'>"DFOP"</span>, <span class='op'>]</span><span class='op'>)</span> - <span class='fu'><a href='https://rdrr.io/r/stats/anova.html'>anova</a></span><span class='op'>(</span><span class='va'>f_nlme_sfo</span>, <span class='va'>f_nlme_dfop</span><span class='op'>)</span> -</div><div class='output co'>#> Model df AIC BIC logLik Test L.Ratio p-value -#> f_nlme_sfo 1 5 625.0539 637.5529 -307.5269 -#> f_nlme_dfop 2 9 495.1270 517.6253 -238.5635 1 vs 2 137.9269 <.0001</div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>f_nlme_dfop</span><span class='op'>)</span> -</div><div class='output co'>#> Kinetic nonlinear mixed-effects model fit by maximum likelihood -#> -#> Structural model: -#> d_parent/dt = - ((k1 * g * exp(-k1 * time) + k2 * (1 - g) * exp(-k2 * -#> time)) / (g * exp(-k1 * time) + (1 - g) * exp(-k2 * time))) -#> * parent -#> -#> Data: -#> 90 observations of 1 variable(s) grouped in 5 datasets -#> -#> Log-likelihood: -238.6 -#> -#> Fixed effects: -#> list(parent_0 ~ 1, log_k1 ~ 1, log_k2 ~ 1, g_qlogis ~ 1) -#> parent_0 log_k1 log_k2 g_qlogis -#> 94.1702 -1.8002 -4.1474 0.0324 -#> -#> Random effects: -#> Formula: list(parent_0 ~ 1, log_k1 ~ 1, log_k2 ~ 1, g_qlogis ~ 1) -#> Level: ds -#> Structure: Diagonal -#> parent_0 log_k1 log_k2 g_qlogis Residual -#> StdDev: 2.488 0.8447 1.33 0.4652 2.321 -#> </div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>f_nlme_dfop</span><span class='op'>)</span> -</div><div class='img'><img src='nlme.mmkin-1.png' alt='' width='700' height='433' /></div><div class='input'> <span class='fu'><a href='endpoints.html'>endpoints</a></span><span class='op'>(</span><span class='va'>f_nlme_dfop</span><span class='op'>)</span> -</div><div class='output co'>#> $distimes -#> DT50 DT90 DT50back DT50_k1 DT50_k2 -#> parent 10.79857 100.7937 30.34193 4.193938 43.85443 -#> </div><div class='input'> - <span class='va'>ds_2</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/lapply.html'>lapply</a></span><span class='op'>(</span><span class='va'>experimental_data_for_UBA_2019</span><span class='op'>[</span><span class='fl'>6</span><span class='op'>:</span><span class='fl'>10</span><span class='op'>]</span>, - <span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='va'>x</span><span class='op'>$</span><span class='va'>data</span><span class='op'>[</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"name"</span>, <span class='st'>"time"</span>, <span class='st'>"value"</span><span class='op'>)</span><span class='op'>]</span><span class='op'>)</span> - <span class='va'>m_sfo_sfo</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"A1"</span><span class='op'>)</span>, - A1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, use_of_ff <span class='op'>=</span> <span class='st'>"min"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - <span class='va'>m_sfo_sfo_ff</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"A1"</span><span class='op'>)</span>, - A1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, use_of_ff <span class='op'>=</span> <span class='st'>"max"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - <span class='va'>m_dfop_sfo</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"DFOP"</span>, <span class='st'>"A1"</span><span class='op'>)</span>, - A1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - - <span class='va'>f_2</span> <span class='op'><-</span> <span class='fu'><a href='mmkin.html'>mmkin</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span><span class='st'>"SFO-SFO"</span> <span class='op'>=</span> <span class='va'>m_sfo_sfo</span>, - <span class='st'>"SFO-SFO-ff"</span> <span class='op'>=</span> <span class='va'>m_sfo_sfo_ff</span>, - <span class='st'>"DFOP-SFO"</span> <span class='op'>=</span> <span class='va'>m_dfop_sfo</span><span class='op'>)</span>, - <span class='va'>ds_2</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - - <span class='va'>f_nlme_sfo_sfo</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme</a></span><span class='op'>(</span><span class='va'>f_2</span><span class='op'>[</span><span class='st'>"SFO-SFO"</span>, <span class='op'>]</span><span class='op'>)</span> - <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>f_nlme_sfo_sfo</span><span class='op'>)</span> -</div><div class='img'><img src='nlme.mmkin-2.png' alt='' width='700' height='433' /></div><div class='input'> - <span class='co'># With formation fractions this does not coverge with defaults</span> - <span class='co'># f_nlme_sfo_sfo_ff <- nlme(f_2["SFO-SFO-ff", ])</span> - <span class='co'>#plot(f_nlme_sfo_sfo_ff)</span> - - <span class='co'># For the following, we need to increase pnlsMaxIter and the tolerance</span> - <span class='co'># to get convergence</span> - <span class='va'>f_nlme_dfop_sfo</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme</a></span><span class='op'>(</span><span class='va'>f_2</span><span class='op'>[</span><span class='st'>"DFOP-SFO"</span>, <span class='op'>]</span>, - control <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>pnlsMaxIter <span class='op'>=</span> <span class='fl'>120</span>, tolerance <span class='op'>=</span> <span class='fl'>5e-4</span><span class='op'>)</span><span class='op'>)</span> - - <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>f_nlme_dfop_sfo</span><span class='op'>)</span> -</div><div class='img'><img src='nlme.mmkin-3.png' alt='' width='700' height='433' /></div><div class='input'> - <span class='fu'><a href='https://rdrr.io/r/stats/anova.html'>anova</a></span><span class='op'>(</span><span class='va'>f_nlme_dfop_sfo</span>, <span class='va'>f_nlme_sfo_sfo</span><span class='op'>)</span> -</div><div class='output co'>#> Model df AIC BIC logLik Test L.Ratio p-value -#> f_nlme_dfop_sfo 1 13 843.8548 884.6201 -408.9274 -#> f_nlme_sfo_sfo 2 9 1085.1821 1113.4043 -533.5910 1 vs 2 249.3273 <.0001</div><div class='input'> - <span class='fu'><a href='endpoints.html'>endpoints</a></span><span class='op'>(</span><span class='va'>f_nlme_sfo_sfo</span><span class='op'>)</span> -</div><div class='output co'>#> $ff -#> parent_sink parent_A1 A1_sink -#> 0.5912432 0.4087568 1.0000000 -#> -#> $distimes -#> DT50 DT90 -#> parent 19.13518 63.5657 -#> A1 66.02155 219.3189 -#> </div><div class='input'> <span class='fu'><a href='endpoints.html'>endpoints</a></span><span class='op'>(</span><span class='va'>f_nlme_dfop_sfo</span><span class='op'>)</span> -</div><div class='output co'>#> $ff -#> parent_A1 parent_sink -#> 0.2768575 0.7231425 -#> -#> $distimes -#> DT50 DT90 DT50back DT50_k1 DT50_k2 -#> parent 11.07091 104.6320 31.49737 4.462384 46.20825 -#> A1 162.30492 539.1653 NA NA NA -#> </div><div class='input'> - <span class='kw'>if</span> <span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/length.html'>length</a></span><span class='op'>(</span><span class='fu'>findFunction</span><span class='op'>(</span><span class='st'>"varConstProp"</span><span class='op'>)</span><span class='op'>)</span> <span class='op'>></span> <span class='fl'>0</span><span class='op'>)</span> <span class='op'>{</span> <span class='co'># tc error model for nlme available</span> - <span class='co'># Attempts to fit metabolite kinetics with the tc error model are possible,</span> - <span class='co'># but need tweeking of control values and sometimes do not converge</span> - - <span class='va'>f_tc</span> <span class='op'><-</span> <span class='fu'><a href='mmkin.html'>mmkin</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"DFOP"</span><span class='op'>)</span>, <span class='va'>ds</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span><span class='op'>)</span> - <span class='va'>f_nlme_sfo_tc</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme</a></span><span class='op'>(</span><span class='va'>f_tc</span><span class='op'>[</span><span class='st'>"SFO"</span>, <span class='op'>]</span><span class='op'>)</span> - <span class='va'>f_nlme_dfop_tc</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme</a></span><span class='op'>(</span><span class='va'>f_tc</span><span class='op'>[</span><span class='st'>"DFOP"</span>, <span class='op'>]</span><span class='op'>)</span> - <span class='fu'><a href='https://rdrr.io/r/stats/AIC.html'>AIC</a></span><span class='op'>(</span><span class='va'>f_nlme_sfo</span>, <span class='va'>f_nlme_sfo_tc</span>, <span class='va'>f_nlme_dfop</span>, <span class='va'>f_nlme_dfop_tc</span><span class='op'>)</span> - <span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>f_nlme_dfop_tc</span><span class='op'>)</span> - <span class='op'>}</span> -</div><div class='output co'>#> Kinetic nonlinear mixed-effects model fit by maximum likelihood -#> -#> Structural model: -#> d_parent/dt = - ((k1 * g * exp(-k1 * time) + k2 * (1 - g) * exp(-k2 * -#> time)) / (g * exp(-k1 * time) + (1 - g) * exp(-k2 * time))) -#> * parent -#> -#> Data: -#> 90 observations of 1 variable(s) grouped in 5 datasets -#> -#> Log-likelihood: -238.4 -#> -#> Fixed effects: -#> list(parent_0 ~ 1, log_k1 ~ 1, log_k2 ~ 1, g_qlogis ~ 1) -#> parent_0 log_k1 log_k2 g_qlogis -#> 94.04774 -1.82340 -4.16716 0.05686 -#> -#> Random effects: -#> Formula: list(parent_0 ~ 1, log_k1 ~ 1, log_k2 ~ 1, g_qlogis ~ 1) -#> Level: ds -#> Structure: Diagonal -#> parent_0 log_k1 log_k2 g_qlogis Residual -#> StdDev: 2.474 0.85 1.337 0.4659 1 -#> -#> Variance function: -#> Structure: Constant plus proportion of variance covariate -#> Formula: ~fitted(.) -#> Parameter estimates: -#> const prop -#> 2.23223147 0.01262395 </div><div class='input'> - <span class='va'>f_2_obs</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/update.html'>update</a></span><span class='op'>(</span><span class='va'>f_2</span>, error_model <span class='op'>=</span> <span class='st'>"obs"</span><span class='op'>)</span> - <span class='va'>f_nlme_sfo_sfo_obs</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme</a></span><span class='op'>(</span><span class='va'>f_2_obs</span><span class='op'>[</span><span class='st'>"SFO-SFO"</span>, <span class='op'>]</span><span class='op'>)</span> - <span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>f_nlme_sfo_sfo_obs</span><span class='op'>)</span> -</div><div class='output co'>#> Kinetic nonlinear mixed-effects model fit by maximum likelihood -#> -#> Structural model: -#> d_parent/dt = - k_parent_sink * parent - k_parent_A1 * parent -#> d_A1/dt = + k_parent_A1 * parent - k_A1_sink * A1 -#> -#> Data: -#> 170 observations of 2 variable(s) grouped in 5 datasets -#> -#> Log-likelihood: -473 -#> -#> Fixed effects: -#> list(parent_0 ~ 1, log_k_parent_sink ~ 1, log_k_parent_A1 ~ 1, log_k_A1_sink ~ 1) -#> parent_0 log_k_parent_sink log_k_parent_A1 log_k_A1_sink -#> 87.976 -3.670 -4.164 -4.645 -#> -#> Random effects: -#> Formula: list(parent_0 ~ 1, log_k_parent_sink ~ 1, log_k_parent_A1 ~ 1, log_k_A1_sink ~ 1) -#> Level: ds -#> Structure: Diagonal -#> parent_0 log_k_parent_sink log_k_parent_A1 log_k_A1_sink Residual -#> StdDev: 3.992 1.777 1.055 0.4821 6.483 -#> -#> Variance function: -#> Structure: Different standard deviations per stratum -#> Formula: ~1 | name -#> Parameter estimates: -#> parent A1 -#> 1.0000000 0.2049995 </div><div class='input'> <span class='va'>f_nlme_dfop_sfo_obs</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme</a></span><span class='op'>(</span><span class='va'>f_2_obs</span><span class='op'>[</span><span class='st'>"DFOP-SFO"</span>, <span class='op'>]</span>, - control <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>pnlsMaxIter <span class='op'>=</span> <span class='fl'>120</span>, tolerance <span class='op'>=</span> <span class='fl'>5e-4</span><span class='op'>)</span><span class='op'>)</span> - - <span class='va'>f_2_tc</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/update.html'>update</a></span><span class='op'>(</span><span class='va'>f_2</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span><span class='op'>)</span> - <span class='co'># f_nlme_sfo_sfo_tc <- nlme(f_2_tc["SFO-SFO", ]) # No convergence with 50 iterations</span> - <span class='co'># f_nlme_dfop_sfo_tc <- nlme(f_2_tc["DFOP-SFO", ],</span> - <span class='co'># control = list(pnlsMaxIter = 120, tolerance = 5e-4)) # Error in X[, fmap[[nm]]] <- gradnm</span> +<code><a href="https://rdrr.io/pkg/nlme/man/intervals.html" class="external-link">nlme::intervals()</a></code>, <code><a href="https://rdrr.io/pkg/nlme/man/anova.lme.html" class="external-link">nlme::anova.lme()</a></code> and <code><a href="https://rdrr.io/pkg/nlme/man/coef.lme.html" class="external-link">nlme::coef.lme()</a></code>.</p> + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p><code><a href="nlme.html">nlme_function()</a></code>, <a href="plot.mixed.mmkin.html">plot.mixed.mmkin</a>, <a href="summary.nlme.mmkin.html">summary.nlme.mmkin</a></p></div> + </div> - <span class='fu'><a href='https://rdrr.io/r/stats/anova.html'>anova</a></span><span class='op'>(</span><span class='va'>f_nlme_dfop_sfo</span>, <span class='va'>f_nlme_dfop_sfo_obs</span><span class='op'>)</span> -</div><div class='output co'>#> Model df AIC BIC logLik Test L.Ratio -#> f_nlme_dfop_sfo 1 13 843.8548 884.6201 -408.9274 -#> f_nlme_dfop_sfo_obs 2 14 817.5338 861.4350 -394.7669 1 vs 2 28.32093 -#> p-value -#> f_nlme_dfop_sfo -#> f_nlme_dfop_sfo_obs <.0001</div><div class='input'> -<span class='co'># }</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="va">ds</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="va">experimental_data_for_UBA_2019</span><span class="op">[</span><span class="fl">6</span><span class="op">:</span><span class="fl">10</span><span class="op">]</span>,</span> +<span class="r-in"> <span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu"><a href="https://rdrr.io/r/base/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">x</span><span class="op">$</span><span class="va">data</span><span class="op">[</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"name"</span>, <span class="st">"time"</span>, <span class="st">"value"</span><span class="op">)</span><span class="op">]</span>, <span class="va">name</span> <span class="op">==</span> <span class="st">"parent"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"DFOP"</span><span class="op">)</span>, <span class="va">ds</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, cores <span class="op">=</span> <span class="fl">1</span><span class="op">)</span></span> +<span class="r-in"><span class="kw"><a href="https://rdrr.io/r/base/library.html" class="external-link">library</a></span><span class="op">(</span><span class="va"><a href="https://svn.r-project.org/R-packages/trunk/nlme/" class="external-link">nlme</a></span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_nlme_sfo</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></span><span class="op">(</span><span class="va">f</span><span class="op">[</span><span class="st">"SFO"</span>, <span class="op">]</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"></span> +<span class="r-in"> <span class="va">f_nlme_dfop</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></span><span class="op">(</span><span class="va">f</span><span class="op">[</span><span class="st">"DFOP"</span>, <span class="op">]</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/stats/anova.html" class="external-link">anova</a></span><span class="op">(</span><span class="va">f_nlme_sfo</span>, <span class="va">f_nlme_dfop</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Model df AIC BIC logLik Test L.Ratio p-value</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlme_sfo 1 5 625.0539 637.5529 -307.5269 </span> +<span class="r-out co"><span class="r-pr">#></span> f_nlme_dfop 2 9 495.1270 517.6253 -238.5635 1 vs 2 137.9269 <.0001</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">f_nlme_dfop</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Kinetic nonlinear mixed-effects model fit by maximum likelihood</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Structural model:</span> +<span class="r-out co"><span class="r-pr">#></span> d_parent/dt = - ((k1 * g * exp(-k1 * time) + k2 * (1 - g) * exp(-k2 *</span> +<span class="r-out co"><span class="r-pr">#></span> time)) / (g * exp(-k1 * time) + (1 - g) * exp(-k2 * time)))</span> +<span class="r-out co"><span class="r-pr">#></span> * parent</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Data:</span> +<span class="r-out co"><span class="r-pr">#></span> 90 observations of 1 variable(s) grouped in 5 datasets</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Log-likelihood: -238.6</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fixed effects:</span> +<span class="r-out co"><span class="r-pr">#></span> list(parent_0 ~ 1, log_k1 ~ 1, log_k2 ~ 1, g_qlogis ~ 1) </span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_k1 log_k2 g_qlogis </span> +<span class="r-out co"><span class="r-pr">#></span> 94.1702 -1.8002 -4.1474 0.0324 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Random effects:</span> +<span class="r-out co"><span class="r-pr">#></span> Formula: list(parent_0 ~ 1, log_k1 ~ 1, log_k2 ~ 1, g_qlogis ~ 1)</span> +<span class="r-out co"><span class="r-pr">#></span> Level: ds</span> +<span class="r-out co"><span class="r-pr">#></span> Structure: Diagonal</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_k1 log_k2 g_qlogis Residual</span> +<span class="r-out co"><span class="r-pr">#></span> StdDev: 2.488 0.8447 1.33 0.4652 2.321</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_nlme_dfop</span><span class="op">)</span></span> +<span class="r-plt img"><img src="nlme.mmkin-1.png" alt="" width="700" height="433"></span> +<span class="r-in"> <span class="fu"><a href="endpoints.html">endpoints</a></span><span class="op">(</span><span class="va">f_nlme_dfop</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> $distimes</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90 DT50back DT50_k1 DT50_k2</span> +<span class="r-out co"><span class="r-pr">#></span> parent 10.79857 100.7937 30.34193 4.193938 43.85443</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"></span> +<span class="r-in"> <span class="va">ds_2</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="va">experimental_data_for_UBA_2019</span><span class="op">[</span><span class="fl">6</span><span class="op">:</span><span class="fl">10</span><span class="op">]</span>,</span> +<span class="r-in"> <span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="va">x</span><span class="op">$</span><span class="va">data</span><span class="op">[</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"name"</span>, <span class="st">"time"</span>, <span class="st">"value"</span><span class="op">)</span><span class="op">]</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">m_sfo_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"A1"</span><span class="op">)</span>,</span> +<span class="r-in"> A1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>, use_of_ff <span class="op">=</span> <span class="st">"min"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">m_sfo_sfo_ff</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"A1"</span><span class="op">)</span>,</span> +<span class="r-in"> A1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>, use_of_ff <span class="op">=</span> <span class="st">"max"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">m_dfop_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="st">"A1"</span><span class="op">)</span>,</span> +<span class="r-in"> A1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"> <span class="va">f_2</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="st">"SFO-SFO"</span> <span class="op">=</span> <span class="va">m_sfo_sfo</span>,</span> +<span class="r-in"> <span class="st">"SFO-SFO-ff"</span> <span class="op">=</span> <span class="va">m_sfo_sfo_ff</span>,</span> +<span class="r-in"> <span class="st">"DFOP-SFO"</span> <span class="op">=</span> <span class="va">m_dfop_sfo</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">ds_2</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"> <span class="va">f_nlme_sfo_sfo</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></span><span class="op">(</span><span class="va">f_2</span><span class="op">[</span><span class="st">"SFO-SFO"</span>, <span class="op">]</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_nlme_sfo_sfo</span><span class="op">)</span></span> +<span class="r-plt img"><img src="nlme.mmkin-2.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +<span class="r-in"> <span class="co"># With formation fractions this does not coverge with defaults</span></span> +<span class="r-in"> <span class="co"># f_nlme_sfo_sfo_ff <- nlme(f_2["SFO-SFO-ff", ])</span></span> +<span class="r-in"> <span class="co">#plot(f_nlme_sfo_sfo_ff)</span></span> +<span class="r-in"></span> +<span class="r-in"> <span class="co"># For the following, we need to increase pnlsMaxIter and the tolerance</span></span> +<span class="r-in"> <span class="co"># to get convergence</span></span> +<span class="r-in"> <span class="va">f_nlme_dfop_sfo</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></span><span class="op">(</span><span class="va">f_2</span><span class="op">[</span><span class="st">"DFOP-SFO"</span>, <span class="op">]</span>,</span> +<span class="r-in"> control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>pnlsMaxIter <span class="op">=</span> <span class="fl">120</span>, tolerance <span class="op">=</span> <span class="fl">5e-4</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_nlme_dfop_sfo</span><span class="op">)</span></span> +<span class="r-plt img"><img src="nlme.mmkin-3.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/stats/anova.html" class="external-link">anova</a></span><span class="op">(</span><span class="va">f_nlme_dfop_sfo</span>, <span class="va">f_nlme_sfo_sfo</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Model df AIC BIC logLik Test L.Ratio p-value</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlme_dfop_sfo 1 13 843.8547 884.6201 -408.9274 </span> +<span class="r-out co"><span class="r-pr">#></span> f_nlme_sfo_sfo 2 9 1085.1821 1113.4043 -533.5910 1 vs 2 249.3274 <.0001</span> +<span class="r-in"></span> +<span class="r-in"> <span class="fu"><a href="endpoints.html">endpoints</a></span><span class="op">(</span><span class="va">f_nlme_sfo_sfo</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> $ff</span> +<span class="r-out co"><span class="r-pr">#></span> parent_sink parent_A1 A1_sink </span> +<span class="r-out co"><span class="r-pr">#></span> 0.5912432 0.4087568 1.0000000 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $distimes</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90</span> +<span class="r-out co"><span class="r-pr">#></span> parent 19.13518 63.5657</span> +<span class="r-out co"><span class="r-pr">#></span> A1 66.02155 219.3189</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"> <span class="fu"><a href="endpoints.html">endpoints</a></span><span class="op">(</span><span class="va">f_nlme_dfop_sfo</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> $ff</span> +<span class="r-out co"><span class="r-pr">#></span> parent_A1 parent_sink </span> +<span class="r-out co"><span class="r-pr">#></span> 0.2768574 0.7231426 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $distimes</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90 DT50back DT50_k1 DT50_k2</span> +<span class="r-out co"><span class="r-pr">#></span> parent 11.07091 104.6320 31.49737 4.462383 46.20825</span> +<span class="r-out co"><span class="r-pr">#></span> A1 162.30519 539.1662 NA NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"></span> +<span class="r-in"> <span class="kw">if</span> <span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/length.html" class="external-link">length</a></span><span class="op">(</span><span class="fu">findFunction</span><span class="op">(</span><span class="st">"varConstProp"</span><span class="op">)</span><span class="op">)</span> <span class="op">></span> <span class="fl">0</span><span class="op">)</span> <span class="op">{</span> <span class="co"># tc error model for nlme available</span></span> +<span class="r-in"> <span class="co"># Attempts to fit metabolite kinetics with the tc error model are possible,</span></span> +<span class="r-in"> <span class="co"># but need tweeking of control values and sometimes do not converge</span></span> +<span class="r-in"></span> +<span class="r-in"> <span class="va">f_tc</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"DFOP"</span><span class="op">)</span>, <span class="va">ds</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"tc"</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">f_nlme_sfo_tc</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></span><span class="op">(</span><span class="va">f_tc</span><span class="op">[</span><span class="st">"SFO"</span>, <span class="op">]</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">f_nlme_dfop_tc</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></span><span class="op">(</span><span class="va">f_tc</span><span class="op">[</span><span class="st">"DFOP"</span>, <span class="op">]</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">AIC</a></span><span class="op">(</span><span class="va">f_nlme_sfo</span>, <span class="va">f_nlme_sfo_tc</span>, <span class="va">f_nlme_dfop</span>, <span class="va">f_nlme_dfop_tc</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">f_nlme_dfop_tc</span><span class="op">)</span></span> +<span class="r-in"> <span class="op">}</span></span> +<span class="r-out co"><span class="r-pr">#></span> Kinetic nonlinear mixed-effects model fit by maximum likelihood</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Structural model:</span> +<span class="r-out co"><span class="r-pr">#></span> d_parent/dt = - ((k1 * g * exp(-k1 * time) + k2 * (1 - g) * exp(-k2 *</span> +<span class="r-out co"><span class="r-pr">#></span> time)) / (g * exp(-k1 * time) + (1 - g) * exp(-k2 * time)))</span> +<span class="r-out co"><span class="r-pr">#></span> * parent</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Data:</span> +<span class="r-out co"><span class="r-pr">#></span> 90 observations of 1 variable(s) grouped in 5 datasets</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Log-likelihood: -238.4</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fixed effects:</span> +<span class="r-out co"><span class="r-pr">#></span> list(parent_0 ~ 1, log_k1 ~ 1, log_k2 ~ 1, g_qlogis ~ 1) </span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_k1 log_k2 g_qlogis </span> +<span class="r-out co"><span class="r-pr">#></span> 94.04774 -1.82340 -4.16716 0.05686 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Random effects:</span> +<span class="r-out co"><span class="r-pr">#></span> Formula: list(parent_0 ~ 1, log_k1 ~ 1, log_k2 ~ 1, g_qlogis ~ 1)</span> +<span class="r-out co"><span class="r-pr">#></span> Level: ds</span> +<span class="r-out co"><span class="r-pr">#></span> Structure: Diagonal</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_k1 log_k2 g_qlogis Residual</span> +<span class="r-out co"><span class="r-pr">#></span> StdDev: 2.474 0.85 1.337 0.4659 1</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Variance function:</span> +<span class="r-out co"><span class="r-pr">#></span> Structure: Constant plus proportion of variance covariate</span> +<span class="r-out co"><span class="r-pr">#></span> Formula: ~fitted(.) </span> +<span class="r-out co"><span class="r-pr">#></span> Parameter estimates:</span> +<span class="r-out co"><span class="r-pr">#></span> const prop </span> +<span class="r-out co"><span class="r-pr">#></span> 2.23223147 0.01262395 </span> +<span class="r-in"></span> +<span class="r-in"> <span class="va">f_2_obs</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/update.html" class="external-link">update</a></span><span class="op">(</span><span class="va">f_2</span>, error_model <span class="op">=</span> <span class="st">"obs"</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">f_nlme_sfo_sfo_obs</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></span><span class="op">(</span><span class="va">f_2_obs</span><span class="op">[</span><span class="st">"SFO-SFO"</span>, <span class="op">]</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">f_nlme_sfo_sfo_obs</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Kinetic nonlinear mixed-effects model fit by maximum likelihood</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Structural model:</span> +<span class="r-out co"><span class="r-pr">#></span> d_parent/dt = - k_parent_sink * parent - k_parent_A1 * parent</span> +<span class="r-out co"><span class="r-pr">#></span> d_A1/dt = + k_parent_A1 * parent - k_A1_sink * A1</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Data:</span> +<span class="r-out co"><span class="r-pr">#></span> 170 observations of 2 variable(s) grouped in 5 datasets</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Log-likelihood: -473</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fixed effects:</span> +<span class="r-out co"><span class="r-pr">#></span> list(parent_0 ~ 1, log_k_parent_sink ~ 1, log_k_parent_A1 ~ 1, log_k_A1_sink ~ 1) </span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_k_parent_sink log_k_parent_A1 log_k_A1_sink </span> +<span class="r-out co"><span class="r-pr">#></span> 87.976 -3.670 -4.164 -4.645 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Random effects:</span> +<span class="r-out co"><span class="r-pr">#></span> Formula: list(parent_0 ~ 1, log_k_parent_sink ~ 1, log_k_parent_A1 ~ 1, log_k_A1_sink ~ 1)</span> +<span class="r-out co"><span class="r-pr">#></span> Level: ds</span> +<span class="r-out co"><span class="r-pr">#></span> Structure: Diagonal</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_k_parent_sink log_k_parent_A1 log_k_A1_sink Residual</span> +<span class="r-out co"><span class="r-pr">#></span> StdDev: 3.992 1.777 1.055 0.4821 6.483</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Variance function:</span> +<span class="r-out co"><span class="r-pr">#></span> Structure: Different standard deviations per stratum</span> +<span class="r-out co"><span class="r-pr">#></span> Formula: ~1 | name </span> +<span class="r-out co"><span class="r-pr">#></span> Parameter estimates:</span> +<span class="r-out co"><span class="r-pr">#></span> parent A1 </span> +<span class="r-out co"><span class="r-pr">#></span> 1.0000000 0.2049995 </span> +<span class="r-in"> <span class="va">f_nlme_dfop_sfo_obs</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></span><span class="op">(</span><span class="va">f_2_obs</span><span class="op">[</span><span class="st">"DFOP-SFO"</span>, <span class="op">]</span>,</span> +<span class="r-in"> control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>pnlsMaxIter <span class="op">=</span> <span class="fl">120</span>, tolerance <span class="op">=</span> <span class="fl">5e-4</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"> <span class="va">f_2_tc</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/update.html" class="external-link">update</a></span><span class="op">(</span><span class="va">f_2</span>, error_model <span class="op">=</span> <span class="st">"tc"</span><span class="op">)</span></span> +<span class="r-in"> <span class="co"># f_nlme_sfo_sfo_tc <- nlme(f_2_tc["SFO-SFO", ]) # No convergence with 50 iterations</span></span> +<span class="r-in"> <span class="co"># f_nlme_dfop_sfo_tc <- nlme(f_2_tc["DFOP-SFO", ],</span></span> +<span class="r-in"> <span class="co"># control = list(pnlsMaxIter = 120, tolerance = 5e-4)) # Error in X[, fmap[[nm]]] <- gradnm</span></span> +<span class="r-in"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/stats/anova.html" class="external-link">anova</a></span><span class="op">(</span><span class="va">f_nlme_dfop_sfo</span>, <span class="va">f_nlme_dfop_sfo_obs</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Model df AIC BIC logLik Test L.Ratio</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlme_dfop_sfo 1 13 843.8547 884.6201 -408.9274 </span> +<span class="r-out co"><span class="r-pr">#></span> f_nlme_dfop_sfo_obs 2 14 817.5338 861.4350 -394.7669 1 vs 2 28.32091</span> +<span class="r-out co"><span class="r-pr">#></span> p-value</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlme_dfop_sfo </span> +<span class="r-out co"><span class="r-pr">#></span> f_nlme_dfop_sfo_obs <.0001</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/nlmixr.mmkin-1.png b/docs/reference/nlmixr.mmkin-1.png Binary files differnew file mode 100644 index 00000000..42a266e5 --- /dev/null +++ b/docs/reference/nlmixr.mmkin-1.png diff --git a/docs/reference/nlmixr.mmkin-2.png b/docs/reference/nlmixr.mmkin-2.png Binary files differnew file mode 100644 index 00000000..0c440fa8 --- /dev/null +++ b/docs/reference/nlmixr.mmkin-2.png diff --git a/docs/reference/nlmixr.mmkin.html b/docs/reference/nlmixr.mmkin.html new file mode 100644 index 00000000..deb8bacc --- /dev/null +++ b/docs/reference/nlmixr.mmkin.html @@ -0,0 +1,15455 @@ +<!DOCTYPE html> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Fit nonlinear mixed models using nlmixr — nlmixr.mmkin • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Fit nonlinear mixed models using nlmixr — nlmixr.mmkin"><meta property="og:description" content="This function uses nlmixr::nlmixr() as a backend for fitting nonlinear mixed +effects models created from mmkin row objects using the Stochastic Approximation +Expectation Maximisation algorithm (SAEM) or First Order Conditional +Estimation with Interaction (FOCEI)."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> +<script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> +<script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + + + <div class="container template-reference-topic"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <div class="container"> + <div class="navbar-header"> + <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> + <span class="sr-only">Toggle navigation</span> + <span class="icon-bar"></span> + <span class="icon-bar"></span> + <span class="icon-bar"></span> + </button> + <span class="navbar-brand"> + <a class="navbar-link" href="../index.html">mkin</a> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> + </span> + </div> + + <div id="navbar" class="navbar-collapse collapse"> + <ul class="nav navbar-nav"><li> + <a href="../reference/index.html">Functions and data</a> +</li> +<li class="dropdown"> + <a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-expanded="false"> + Articles + + <span class="caret"></span> + </a> + <ul class="dropdown-menu" role="menu"><li> + <a href="../articles/mkin.html">Introduction to mkin</a> + </li> + <li> + <a href="../articles/FOCUS_D.html">Example evaluation of FOCUS Example Dataset D</a> + </li> + <li> + <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> + </li> + <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> + <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> + </li> + <li> + <a href="../articles/web_only/compiled_models.html">Performance benefit by using compiled model definitions in mkin</a> + </li> + <li> + <a href="../articles/twa.html">Calculation of time weighted average concentrations with mkin</a> + </li> + <li> + <a href="../articles/web_only/NAFTA_examples.html">Example evaluation of NAFTA SOP Attachment examples</a> + </li> + <li> + <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> + </li> + </ul></li> +<li> + <a href="../news/index.html">News</a> +</li> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> + <span class="fab fa-github fa-lg"></span> + + </a> +</li> + </ul></div><!--/.nav-collapse --> + </div><!--/.container --> +</div><!--/.navbar --> + + + + </header><div class="row"> + <div class="col-md-9 contents"> + <div class="page-header"> + <h1>Fit nonlinear mixed models using nlmixr</h1> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/nlmixr.R" class="external-link"><code>R/nlmixr.R</code></a></small> + <div class="hidden name"><code>nlmixr.mmkin.Rd</code></div> + </div> + + <div class="ref-description"> + <p>This function uses <code><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr::nlmixr()</a></code> as a backend for fitting nonlinear mixed +effects models created from <a href="mmkin.html">mmkin</a> row objects using the Stochastic Approximation +Expectation Maximisation algorithm (SAEM) or First Order Conditional +Estimation with Interaction (FOCEI).</p> + </div> + + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for mmkin</span> +<span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span> + <span class="va">object</span>, + data <span class="op">=</span> <span class="cn">NULL</span>, + est <span class="op">=</span> <span class="cn">NULL</span>, + control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="op">)</span>, + table <span class="op">=</span> <span class="fu">tableControl</span><span class="op">(</span><span class="op">)</span>, + error_model <span class="op">=</span> <span class="va">object</span><span class="op">[[</span><span class="fl">1</span><span class="op">]</span><span class="op">]</span><span class="op">$</span><span class="va">err_mod</span>, + test_log_parms <span class="op">=</span> <span class="cn">TRUE</span>, + conf.level <span class="op">=</span> <span class="fl">0.6</span>, + degparms_start <span class="op">=</span> <span class="st">"auto"</span>, + eta_start <span class="op">=</span> <span class="st">"auto"</span>, + <span class="va">...</span>, + save <span class="op">=</span> <span class="cn">NULL</span>, + envir <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/sys.parent.html" class="external-link">parent.frame</a></span><span class="op">(</span><span class="op">)</span> +<span class="op">)</span> + +<span class="co"># S3 method for nlmixr.mmkin</span> +<span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">x</span>, digits <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/Extremes.html" class="external-link">max</a></span><span class="op">(</span><span class="fl">3</span>, <span class="fu"><a href="https://rdrr.io/r/base/options.html" class="external-link">getOption</a></span><span class="op">(</span><span class="st">"digits"</span><span class="op">)</span> <span class="op">-</span> <span class="fl">3</span><span class="op">)</span>, <span class="va">...</span><span class="op">)</span> + +<span class="fu">nlmixr_model</span><span class="op">(</span> + <span class="va">object</span>, + est <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"saem"</span>, <span class="st">"focei"</span><span class="op">)</span>, + degparms_start <span class="op">=</span> <span class="st">"auto"</span>, + eta_start <span class="op">=</span> <span class="st">"auto"</span>, + test_log_parms <span class="op">=</span> <span class="cn">TRUE</span>, + conf.level <span class="op">=</span> <span class="fl">0.6</span>, + error_model <span class="op">=</span> <span class="va">object</span><span class="op">[[</span><span class="fl">1</span><span class="op">]</span><span class="op">]</span><span class="op">$</span><span class="va">err_mod</span>, + add_attributes <span class="op">=</span> <span class="cn">FALSE</span> +<span class="op">)</span> + +<span class="fu">nlmixr_data</span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>An <a href="mmkin.html">mmkin</a> row object containing several fits of the same +<a href="mkinmod.html">mkinmod</a> model to different datasets</p></dd> +<dt>data</dt> +<dd><p>Not used, as the data are extracted from the mmkin row object</p></dd> +<dt>est</dt> +<dd><p>Estimation method passed to <a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr::nlmixr</a></p></dd> +<dt>control</dt> +<dd><p>Passed to <a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr::nlmixr</a></p></dd> +<dt>table</dt> +<dd><p>Passed to <a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr::nlmixr</a></p></dd> +<dt>error_model</dt> +<dd><p>Optional argument to override the error model which is +being set based on the error model used in the mmkin row object.</p></dd> +<dt>test_log_parms</dt> +<dd><p>If TRUE, an attempt is made to use more robust starting +values for population parameters fitted as log parameters in mkin (like +rate constants) by only considering rate constants that pass the t-test +when calculating mean degradation parameters using <a href="mean_degparms.html">mean_degparms</a>.</p></dd> +<dt>conf.level</dt> +<dd><p>Possibility to adjust the required confidence level +for parameter that are tested if requested by 'test_log_parms'.</p></dd> +<dt>degparms_start</dt> +<dd><p>Parameter values given as a named numeric vector will +be used to override the starting values obtained from the 'mmkin' object.</p></dd> +<dt>eta_start</dt> +<dd><p>Standard deviations on the transformed scale given as a +named numeric vector will be used to override the starting values obtained +from the 'mmkin' object.</p></dd> +<dt>...</dt> +<dd><p>Passed to nlmixr_model</p></dd> +<dt>save</dt> +<dd><p>Passed to <a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr::nlmixr</a></p></dd> +<dt>envir</dt> +<dd><p>Passed to <a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr::nlmixr</a></p></dd> +<dt>x</dt> +<dd><p>An nlmixr.mmkin object to print</p></dd> +<dt>digits</dt> +<dd><p>Number of digits to use for printing</p></dd> +<dt>add_attributes</dt> +<dd><p>Should the starting values used for degradation model +parameters and their distribution and for the error model parameters +be returned as attributes?</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>An S3 object of class 'nlmixr.mmkin', containing the fitted +<a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr::nlmixr</a> object as a list component named 'nm'. The +object also inherits from 'mixed.mmkin'. +An function defining a model suitable for fitting with <a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr::nlmixr</a>. +An dataframe suitable for use with <a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr::nlmixr</a></p> + </div> + <div id="details"> + <h2>Details</h2> + <p>An mmkin row object is essentially a list of mkinfit objects that have been +obtained by fitting the same model to a list of datasets using <a href="mkinfit.html">mkinfit</a>.</p> + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p><a href="summary.nlmixr.mmkin.html">summary.nlmixr.mmkin</a> <a href="plot.mixed.mmkin.html">plot.mixed.mmkin</a></p></div> + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="va">ds</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="va">experimental_data_for_UBA_2019</span><span class="op">[</span><span class="fl">6</span><span class="op">:</span><span class="fl">10</span><span class="op">]</span>,</span> +<span class="r-in"> <span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu"><a href="https://rdrr.io/r/base/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">x</span><span class="op">$</span><span class="va">data</span><span class="op">[</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"name"</span>, <span class="st">"time"</span>, <span class="st">"value"</span><span class="op">)</span><span class="op">]</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">ds</span><span class="op">)</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste</a></span><span class="op">(</span><span class="st">"Dataset"</span>, <span class="fl">6</span><span class="op">:</span><span class="fl">10</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">f_mmkin_parent</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"FOMC"</span>, <span class="st">"DFOP"</span>, <span class="st">"HS"</span><span class="op">)</span>, <span class="va">ds</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, cores <span class="op">=</span> <span class="fl">1</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_mmkin_parent_tc</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"FOMC"</span>, <span class="st">"DFOP"</span><span class="op">)</span>, <span class="va">ds</span>, error_model <span class="op">=</span> <span class="st">"tc"</span>,</span> +<span class="r-in"> cores <span class="op">=</span> <span class="fl">1</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="kw"><a href="https://rdrr.io/r/base/library.html" class="external-link">library</a></span><span class="op">(</span><span class="va"><a href="https://github.com/nlmixrdevelopment/nlmixr" class="external-link">nlmixr</a></span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> Attaching package: ‘nlmixr’</span> +<span class="r-msg co"><span class="r-pr">#></span> The following object is masked from ‘package:mkin’:</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> saem</span> +<span class="r-in"><span class="va">f_nlmixr_sfo_saem</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_parent</span><span class="op">[</span><span class="st">"SFO"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"saem"</span>,</span> +<span class="r-in"> control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/saemControl.html" class="external-link">saemControl</a></span><span class="op">(</span>print <span class="op">=</span> <span class="fl">0</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → generate SAEM model</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> RxODE 1.1.4 using 8 threads (see ?getRxThreads)</span> +<span class="r-msg co"><span class="r-pr">#></span> no cache: create with `rxCreateCache()`</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-in"><span class="va">f_nlmixr_sfo_focei</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_parent</span><span class="op">[</span><span class="st">"SFO"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"focei"</span>,</span> +<span class="r-in"> control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/foceiControl.html" class="external-link">foceiControl</a></span><span class="op">(</span>print <span class="op">=</span> <span class="fl">0</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-out co"><span class="r-pr">#></span> calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>initial ETAs were nudged; (can control by foceiControl(etaNudge=., etaNudge2=))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>ETAs were reset to zero during optimization; (Can control by foceiControl(resetEtaP=.))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>gradient problems with initial estimate and covariance; see $scaleInfo</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">f_nlmixr_fomc_saem</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_parent</span><span class="op">[</span><span class="st">"FOMC"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"saem"</span>,</span> +<span class="r-in"> control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/saemControl.html" class="external-link">saemControl</a></span><span class="op">(</span>print <span class="op">=</span> <span class="fl">0</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → generate SAEM model</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-in"><span class="va">f_nlmixr_fomc_focei</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_parent</span><span class="op">[</span><span class="st">"FOMC"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"focei"</span>,</span> +<span class="r-in"> control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/foceiControl.html" class="external-link">foceiControl</a></span><span class="op">(</span>print <span class="op">=</span> <span class="fl">0</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-out co"><span class="r-pr">#></span> calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>initial ETAs were nudged; (can control by foceiControl(etaNudge=., etaNudge2=))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>ETAs were reset to zero during optimization; (Can control by foceiControl(resetEtaP=.))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>last objective function was not at minimum, possible problems in optimization</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>gradient problems with initial estimate and covariance; see $scaleInfo</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">f_nlmixr_dfop_saem</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_parent</span><span class="op">[</span><span class="st">"DFOP"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"saem"</span>,</span> +<span class="r-in"> control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/saemControl.html" class="external-link">saemControl</a></span><span class="op">(</span>print <span class="op">=</span> <span class="fl">0</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → generate SAEM model</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-in"><span class="va">f_nlmixr_dfop_focei</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_parent</span><span class="op">[</span><span class="st">"DFOP"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"focei"</span>,</span> +<span class="r-in"> control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/foceiControl.html" class="external-link">foceiControl</a></span><span class="op">(</span>print <span class="op">=</span> <span class="fl">0</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-out co"><span class="r-pr">#></span> calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>initial ETAs were nudged; (can control by foceiControl(etaNudge=., etaNudge2=))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>ETAs were reset to zero during optimization; (Can control by foceiControl(resetEtaP=.))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>gradient problems with initial estimate and covariance; see $scaleInfo</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">f_nlmixr_hs_saem</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_parent</span><span class="op">[</span><span class="st">"HS"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"saem"</span>,</span> +<span class="r-in"> control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/saemControl.html" class="external-link">saemControl</a></span><span class="op">(</span>print <span class="op">=</span> <span class="fl">0</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → generate SAEM model</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-in"><span class="va">f_nlmixr_hs_focei</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_parent</span><span class="op">[</span><span class="st">"HS"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"focei"</span>,</span> +<span class="r-in"> control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/foceiControl.html" class="external-link">foceiControl</a></span><span class="op">(</span>print <span class="op">=</span> <span class="fl">0</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-out co"><span class="r-pr">#></span> calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>initial ETAs were nudged; (can control by foceiControl(etaNudge=., etaNudge2=))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>ETAs were reset to zero during optimization; (Can control by foceiControl(resetEtaP=.))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>last objective function was not at minimum, possible problems in optimization</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>using S matrix to calculate covariance, can check sandwich or R matrix with $covRS and $covR</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>gradient problems with initial estimate and covariance; see $scaleInfo</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">f_nlmixr_fomc_saem_tc</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_parent_tc</span><span class="op">[</span><span class="st">"FOMC"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"saem"</span>,</span> +<span class="r-in"> control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/saemControl.html" class="external-link">saemControl</a></span><span class="op">(</span>print <span class="op">=</span> <span class="fl">0</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-in"><span class="va">f_nlmixr_fomc_focei_tc</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_parent_tc</span><span class="op">[</span><span class="st">"FOMC"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"focei"</span>,</span> +<span class="r-in"> control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/foceiControl.html" class="external-link">foceiControl</a></span><span class="op">(</span>print <span class="op">=</span> <span class="fl">0</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>initial ETAs were nudged; (can control by foceiControl(etaNudge=., etaNudge2=))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>ETAs were reset to zero during optimization; (Can control by foceiControl(resetEtaP=.))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>last objective function was not at minimum, possible problems in optimization</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>parameter estimate near boundary; covariance not calculated:</span> +<span class="r-wrn co"><span class="r-pr">#></span> "rsd_high" </span> +<span class="r-wrn co"><span class="r-pr">#></span> use 'getVarCov' to calculate anyway</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>gradient problems with initial estimate; see $scaleInfo</span> +<span class="r-in"></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">AIC</a></span><span class="op">(</span></span> +<span class="r-in"> <span class="va">f_nlmixr_sfo_saem</span><span class="op">$</span><span class="va">nm</span>, <span class="va">f_nlmixr_sfo_focei</span><span class="op">$</span><span class="va">nm</span>,</span> +<span class="r-in"> <span class="va">f_nlmixr_fomc_saem</span><span class="op">$</span><span class="va">nm</span>, <span class="va">f_nlmixr_fomc_focei</span><span class="op">$</span><span class="va">nm</span>,</span> +<span class="r-in"> <span class="va">f_nlmixr_dfop_saem</span><span class="op">$</span><span class="va">nm</span>, <span class="va">f_nlmixr_dfop_focei</span><span class="op">$</span><span class="va">nm</span>,</span> +<span class="r-in"> <span class="va">f_nlmixr_hs_saem</span><span class="op">$</span><span class="va">nm</span>, <span class="va">f_nlmixr_hs_focei</span><span class="op">$</span><span class="va">nm</span>,</span> +<span class="r-in"> <span class="va">f_nlmixr_fomc_saem_tc</span><span class="op">$</span><span class="va">nm</span>, <span class="va">f_nlmixr_fomc_focei_tc</span><span class="op">$</span><span class="va">nm</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating -2LL by Gaussian quadrature (nnodes=3,nsd=1.6)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating -2LL by Gaussian quadrature (nnodes=3,nsd=1.6)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating -2LL by Gaussian quadrature (nnodes=3,nsd=1.6)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating -2LL by Gaussian quadrature (nnodes=3,nsd=1.6)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating -2LL by Gaussian quadrature (nnodes=3,nsd=1.6)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> df AIC</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_sfo_saem$nm 5 624.9492</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_sfo_focei$nm 5 625.0695</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_fomc_saem$nm 7 463.7577</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_fomc_focei$nm 7 468.0861</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_dfop_saem$nm 9 495.1980</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_dfop_focei$nm 9 495.1072</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_hs_saem$nm 9 531.0689</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_hs_focei$nm 9 545.6728</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_fomc_saem_tc$nm 8 462.1411</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_fomc_focei_tc$nm 8 470.0745</span> +<span class="r-in"></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">AIC</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></span><span class="op">(</span><span class="va">f_mmkin_parent</span><span class="op">[</span><span class="st">"FOMC"</span>, <span class="op">]</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 468.0781</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">AIC</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></span><span class="op">(</span><span class="va">f_mmkin_parent</span><span class="op">[</span><span class="st">"HS"</span>, <span class="op">]</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 535.609</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># The FOCEI fit of FOMC with constant variance or the tc error model is best</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_nlmixr_fomc_saem_tc</span><span class="op">)</span></span> +<span class="r-plt img"><img src="nlmixr.mmkin-1.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">sfo_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"A1"</span><span class="op">)</span>,</span> +<span class="r-in"> A1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">fomc_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"FOMC"</span>, <span class="st">"A1"</span><span class="op">)</span>,</span> +<span class="r-in"> A1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">dfop_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="st">"A1"</span><span class="op">)</span>,</span> +<span class="r-in"> A1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">f_mmkin_const</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span></span> +<span class="r-in"> <span class="st">"SFO-SFO"</span> <span class="op">=</span> <span class="va">sfo_sfo</span>, <span class="st">"FOMC-SFO"</span> <span class="op">=</span> <span class="va">fomc_sfo</span>, <span class="st">"DFOP-SFO"</span> <span class="op">=</span> <span class="va">dfop_sfo</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">ds</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"const"</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_mmkin_obs</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span></span> +<span class="r-in"> <span class="st">"SFO-SFO"</span> <span class="op">=</span> <span class="va">sfo_sfo</span>, <span class="st">"FOMC-SFO"</span> <span class="op">=</span> <span class="va">fomc_sfo</span>, <span class="st">"DFOP-SFO"</span> <span class="op">=</span> <span class="va">dfop_sfo</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">ds</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"obs"</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_mmkin_tc</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span></span> +<span class="r-in"> <span class="st">"SFO-SFO"</span> <span class="op">=</span> <span class="va">sfo_sfo</span>, <span class="st">"FOMC-SFO"</span> <span class="op">=</span> <span class="va">fomc_sfo</span>, <span class="st">"DFOP-SFO"</span> <span class="op">=</span> <span class="va">dfop_sfo</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">ds</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"tc"</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="fu">nlmixr_model</span><span class="op">(</span><span class="va">f_mmkin_const</span><span class="op">[</span><span class="st">"SFO-SFO"</span>, <span class="op">]</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Constant variance for more than one variable is not supported for est = 'saem'</span> +<span class="r-msg co"><span class="r-pr">#></span> Changing the error model to 'obs' (variance by observed variable)</span> +<span class="r-out co"><span class="r-pr">#></span> function () </span> +<span class="r-out co"><span class="r-pr">#></span> {</span> +<span class="r-out co"><span class="r-pr">#></span> ini({</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 = 87</span> +<span class="r-out co"><span class="r-pr">#></span> eta.parent_0 ~ 4.2</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent = -3.2</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_parent ~ 1.5</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_A1 = -4.6</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_A1 ~ 0.56</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_qlogis = -0.33</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_parent_qlogis ~ 1.1</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_parent = 4.3</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_A1 = 4.3</span> +<span class="r-out co"><span class="r-pr">#></span> })</span> +<span class="r-out co"><span class="r-pr">#></span> model({</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0_model = parent_0 + eta.parent_0</span> +<span class="r-out co"><span class="r-pr">#></span> parent(0) = parent_0_model</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent = exp(log_k_parent + eta.log_k_parent)</span> +<span class="r-out co"><span class="r-pr">#></span> k_A1 = exp(log_k_A1 + eta.log_k_A1)</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_A1 = expit(f_parent_qlogis + eta.f_parent_qlogis)</span> +<span class="r-out co"><span class="r-pr">#></span> d/dt(parent) = -k_parent * parent</span> +<span class="r-out co"><span class="r-pr">#></span> d/dt(A1) = +f_parent_to_A1 * k_parent * parent - k_A1 * </span> +<span class="r-out co"><span class="r-pr">#></span> A1</span> +<span class="r-out co"><span class="r-pr">#></span> parent ~ add(sigma_parent)</span> +<span class="r-out co"><span class="r-pr">#></span> A1 ~ add(sigma_A1)</span> +<span class="r-out co"><span class="r-pr">#></span> })</span> +<span class="r-out co"><span class="r-pr">#></span> }</span> +<span class="r-out co"><span class="r-pr">#></span> <environment: 0x555564a5b090></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># A single constant variance is currently only possible with est = 'focei' in nlmixr</span></span> +<span class="r-in"><span class="va">f_nlmixr_sfo_sfo_focei_const</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_const</span><span class="op">[</span><span class="st">"SFO-SFO"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"focei"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="font-weight: bold;">Key:</span> U: Unscaled Parameters; X: Back-transformed parameters; G: Gill difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> F: Forward difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> C: Central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> M: Mixed forward and central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> Unscaled parameters for Omegas=chol(solve(omega));</span> +<span class="r-out co"><span class="r-pr">#></span> Diagonals are transformed, as specified by foceiControl(diagXform=)</span> +<span class="r-out co"><span class="r-pr">#></span> |-----+---------------+-----------+-----------+-----------+-----------|</span> +<span class="r-out co"><span class="r-pr">#></span> | #| Objective Fun | parent_0 |log_k_parent | log_k_A1 |f_parent_qlogis |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| sigma | o1 | o2 | o3 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| o4 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 1</span>| 756.61847 | 1.000 | -0.9694 | -1.000 | -0.9068 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8057 | -0.8843 | -0.8798 | -0.8743 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8782 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 756.61847 | 87.00 | -3.200 | -4.600 | -0.3300 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.300 | 0.6985 | 0.9036 | 1.156 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9765 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 756.61847</span> | 87.00 | 0.04076 | 0.01005 | 0.4182 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.300 | 0.6985 | 0.9036 | 1.156 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9765 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | G| Gill Diff. | 104.1 | 0.02915 | 0.3320 | 0.4427 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -29.46 | 6.499 | 3.260 | -8.158 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -5.501 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 2</span>| 4014.8405 | 0.04387 | -0.9697 | -1.003 | -0.9108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5352 | -0.9440 | -0.9098 | -0.7994 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8277 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 4014.8405 | 3.817 | -3.200 | -4.603 | -0.3313 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.882 | 0.6569 | 0.8766 | 1.243 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.026 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 4014.8405</span> | 3.817 | 0.04075 | 0.01002 | 0.4179 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.882 | 0.6569 | 0.8766 | 1.243 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.026 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 3</span>| 784.09766 | 0.9044 | -0.9695 | -1.000 | -0.9072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7786 | -0.8903 | -0.8828 | -0.8668 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8732 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 784.09766 | 78.68 | -3.200 | -4.600 | -0.3301 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.358 | 0.6944 | 0.9009 | 1.165 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9814 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 784.09766</span> | 78.68 | 0.04076 | 0.01005 | 0.4182 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.358 | 0.6944 | 0.9009 | 1.165 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9814 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 4</span>| 755.85897 | 0.9864 | -0.9694 | -1.000 | -0.9068 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8018 | -0.8852 | -0.8803 | -0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8775 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 755.85897 | 85.82 | -3.200 | -4.600 | -0.3300 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.308 | 0.6979 | 0.9032 | 1.157 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9772 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 755.85897</span> | 85.82 | 0.04076 | 0.01005 | 0.4182 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.308 | 0.6979 | 0.9032 | 1.157 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9772 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -10.67 | 0.1182 | 0.2197 | 0.3686 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -28.82 | 3.860 | 3.200 | -8.294 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -5.254 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 5</span>| 755.50135 | 0.9911 | -0.9695 | -1.000 | -0.9070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7893 | -0.8868 | -0.8816 | -0.8697 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8752 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 755.50135 | 86.22 | -3.200 | -4.600 | -0.3301 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.335 | 0.6968 | 0.9020 | 1.161 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9794 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 755.50135</span> | 86.22 | 0.04076 | 0.01005 | 0.4182 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.335 | 0.6968 | 0.9020 | 1.161 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9794 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 6</span>| 755.34910 | 0.9966 | -0.9695 | -1.000 | -0.9072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7744 | -0.8888 | -0.8833 | -0.8654 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8725 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 755.3491 | 86.70 | -3.200 | -4.600 | -0.3301 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.367 | 0.6954 | 0.9005 | 1.166 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9820 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 755.3491</span> | 86.70 | 0.04076 | 0.01005 | 0.4182 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.367 | 0.6954 | 0.9005 | 1.166 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9820 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 73.92 | 0.04965 | 0.3063 | 0.4373 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -23.46 | 5.143 | 2.934 | -7.746 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -5.165 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 7</span>| 754.44379 | 0.9831 | -0.9697 | -1.001 | -0.9076 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7489 | -0.8930 | -0.8865 | -0.8566 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8669 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 754.44379 | 85.53 | -3.200 | -4.601 | -0.3303 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.422 | 0.6925 | 0.8975 | 1.176 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9875 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 754.44379</span> | 85.53 | 0.04075 | 0.01005 | 0.4182 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.422 | 0.6925 | 0.8975 | 1.176 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9875 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -36.39 | 0.1354 | 0.1953 | 0.3724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -19.20 | 3.020 | 2.621 | -7.506 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -4.671 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 8</span>| 753.82350 | 0.9908 | -0.9699 | -1.001 | -0.9085 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7249 | -0.8992 | -0.8910 | -0.8427 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8580 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 753.8235 | 86.20 | -3.200 | -4.601 | -0.3306 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.474 | 0.6881 | 0.8935 | 1.193 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9962 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 753.8235</span> | 86.20 | 0.04074 | 0.01004 | 0.4181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.474 | 0.6881 | 0.8935 | 1.193 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9962 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 25.33 | 0.08213 | 0.2542 | 0.4339 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -14.89 | 3.322 | 2.230 | -6.934 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -4.324 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 9</span>| 753.42397 | 0.9836 | -0.9702 | -1.002 | -0.9101 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7094 | -0.9058 | -0.8962 | -0.8215 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8457 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 753.42397 | 85.57 | -3.201 | -4.602 | -0.3311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.507 | 0.6835 | 0.8888 | 1.217 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.008 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 753.42397</span> | 85.57 | 0.04073 | 0.01003 | 0.4180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.507 | 0.6835 | 0.8888 | 1.217 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.008 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -31.38 | 0.1220 | 0.1752 | 0.4111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -12.58 | 2.402 | 1.769 | -6.044 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -3.541 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 10</span>| 753.10125 | 0.9902 | -0.9707 | -1.003 | -0.9128 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7033 | -0.9147 | -0.8999 | -0.7966 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8328 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 753.10125 | 86.15 | -3.201 | -4.603 | -0.3320 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.520 | 0.6773 | 0.8855 | 1.246 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.021 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 753.10125</span> | 86.15 | 0.04071 | 0.01002 | 0.4178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.520 | 0.6773 | 0.8855 | 1.246 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.021 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 18.19 | 0.07644 | 0.2005 | 0.4693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -11.34 | 2.660 | 1.470 | -4.866 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.908 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 11</span>| 752.83558 | 0.9856 | -0.9716 | -1.004 | -0.9194 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6931 | -0.9294 | -0.8999 | -0.7740 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8246 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.83558 | 85.75 | -3.202 | -4.604 | -0.3342 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.542 | 0.6671 | 0.8855 | 1.272 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.029 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.83558</span> | 85.75 | 0.04067 | 0.01001 | 0.4172 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.542 | 0.6671 | 0.8855 | 1.272 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.029 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -17.42 | 0.09700 | 0.1175 | 0.4453 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -9.793 | 1.829 | 1.489 | -3.997 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.337 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 12</span>| 752.64046 | 0.9898 | -0.9731 | -1.005 | -0.9331 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6718 | -0.9413 | -0.9101 | -0.7759 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8318 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.64046 | 86.12 | -3.204 | -4.605 | -0.3387 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.588 | 0.6587 | 0.8763 | 1.270 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.022 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.64046</span> | 86.12 | 0.04061 | 0.01000 | 0.4161 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.588 | 0.6587 | 0.8763 | 1.270 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.022 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 12.96 | 0.06018 | 0.1556 | 0.4415 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -6.445 | 1.822 | 0.6282 | -4.092 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.761 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 13</span>| 752.52461 | 0.9874 | -0.9741 | -1.006 | -0.9430 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6755 | -0.9483 | -0.9069 | -0.7553 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8127 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.52461 | 85.90 | -3.205 | -4.606 | -0.3420 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.580 | 0.6538 | 0.8792 | 1.294 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.040 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.52461</span> | 85.90 | 0.04057 | 0.009996 | 0.4153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.580 | 0.6538 | 0.8792 | 1.294 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.040 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.319 | 0.06758 | 0.1323 | 0.4528 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -7.018 | 1.348 | 0.9128 | -3.312 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.706 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 14</span>| 752.47650 | 0.9920 | -0.9750 | -1.008 | -0.9578 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6735 | -0.9481 | -0.9014 | -0.7293 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8100 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.4765 | 86.30 | -3.206 | -4.608 | -0.3468 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.584 | 0.6539 | 0.8841 | 1.324 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.043 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.4765</span> | 86.30 | 0.04054 | 0.009974 | 0.4142 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.584 | 0.6539 | 0.8841 | 1.324 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.043 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 26.38 | 0.03719 | 0.08701 | 0.4621 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -6.642 | 1.808 | 1.401 | -2.463 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.595 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 15</span>| 752.37074 | 0.9880 | -0.9759 | -1.009 | -0.9778 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6665 | -0.9465 | -0.9156 | -0.7192 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8239 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.37074 | 85.96 | -3.206 | -4.609 | -0.3534 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.599 | 0.6551 | 0.8713 | 1.335 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.030 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.37074</span> | 85.96 | 0.04050 | 0.009963 | 0.4125 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.599 | 0.6551 | 0.8713 | 1.335 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.030 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.8866 | 0.05090 | -0.01541 | 0.3812 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -5.712 | 1.436 | 0.1646 | -2.191 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.247 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 16</span>| 752.26949 | 0.9921 | -0.9761 | -1.009 | -0.9796 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6402 | -0.9531 | -0.9164 | -0.7091 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8135 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.26949 | 86.31 | -3.207 | -4.609 | -0.3540 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.656 | 0.6505 | 0.8706 | 1.347 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.040 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.26949</span> | 86.31 | 0.04049 | 0.009963 | 0.4124 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.656 | 0.6505 | 0.8706 | 1.347 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.040 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 26.82 | 0.02710 | 0.03892 | 0.4267 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.005 | 1.500 | 0.1022 | -1.862 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.773 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 17</span>| 752.20271 | 0.9873 | -0.9768 | -1.006 | -0.9927 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6361 | -0.9677 | -0.9007 | -0.7162 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7982 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.20271 | 85.89 | -3.207 | -4.606 | -0.3584 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.664 | 0.6403 | 0.8848 | 1.339 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.055 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.20271</span> | 85.89 | 0.04046 | 0.009992 | 0.4114 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.664 | 0.6403 | 0.8848 | 1.339 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.055 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -7.259 | 0.05081 | 0.1320 | 0.4166 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.497 | 0.4663 | 1.471 | -1.984 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.9590 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 18</span>| 752.16826 | 0.9883 | -0.9778 | -1.006 | -1.005 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6437 | -0.9795 | -0.9210 | -0.7076 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7873 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.16826 | 85.98 | -3.208 | -4.606 | -0.3626 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.648 | 0.6320 | 0.8664 | 1.349 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.16826</span> | 85.98 | 0.04042 | 0.009989 | 0.4103 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.648 | 0.6320 | 0.8664 | 1.349 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.732 | 0.03428 | 0.1666 | 0.4265 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.413 | 0.2526 | -0.2557 | -1.689 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3553 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 19</span>| 752.25223 | 0.9952 | -0.9788 | -1.010 | -1.023 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6370 | -0.9826 | -0.9156 | -0.6853 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7912 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.25223 | 86.58 | -3.209 | -4.610 | -0.3684 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.663 | 0.6299 | 0.8713 | 1.374 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.061 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.25223</span> | 86.58 | 0.04038 | 0.009949 | 0.4089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.663 | 0.6299 | 0.8713 | 1.374 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.061 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 20</span>| 752.18605 | 0.9920 | -0.9778 | -1.007 | -1.006 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6387 | -0.9801 | -0.9204 | -0.7040 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7866 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.18605 | 86.30 | -3.208 | -4.607 | -0.3629 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.659 | 0.6316 | 0.8669 | 1.353 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.18605</span> | 86.30 | 0.04042 | 0.009985 | 0.4103 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.659 | 0.6316 | 0.8669 | 1.353 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 21</span>| 752.16428 | 0.9894 | -0.9778 | -1.006 | -1.006 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6422 | -0.9797 | -0.9208 | -0.7065 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7871 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.16428 | 86.08 | -3.208 | -4.606 | -0.3627 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.651 | 0.6319 | 0.8666 | 1.350 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.16428</span> | 86.08 | 0.04042 | 0.009988 | 0.4103 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.651 | 0.6319 | 0.8666 | 1.350 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.144 | 0.02886 | 0.1726 | 0.4333 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.192 | 0.3285 | -0.2407 | -1.661 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3568 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 22</span>| 752.15919 | 0.9884 | -0.9779 | -1.007 | -1.007 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6420 | -0.9798 | -0.9206 | -0.7051 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7874 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.15919 | 85.99 | -3.208 | -4.607 | -0.3630 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.652 | 0.6319 | 0.8668 | 1.352 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.15919</span> | 85.99 | 0.04042 | 0.009985 | 0.4102 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.652 | 0.6319 | 0.8668 | 1.352 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.486 | 0.03361 | 0.1549 | 0.4244 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.177 | 0.2364 | -0.2213 | -1.616 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3570 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 23</span>| 752.15545 | 0.9894 | -0.9779 | -1.007 | -1.007 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6405 | -0.9799 | -0.9204 | -0.7040 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7872 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.15545 | 86.07 | -3.208 | -4.607 | -0.3631 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.655 | 0.6318 | 0.8669 | 1.353 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.15545</span> | 86.07 | 0.04042 | 0.009984 | 0.4102 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.655 | 0.6318 | 0.8669 | 1.353 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.936 | 0.02854 | 0.1600 | 0.4306 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.962 | 0.3065 | -0.2063 | -1.586 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3570 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 24</span>| 752.15077 | 0.9884 | -0.9779 | -1.007 | -1.008 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6403 | -0.9800 | -0.9202 | -0.7026 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7875 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.15077 | 85.99 | -3.209 | -4.607 | -0.3635 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.656 | 0.6317 | 0.8672 | 1.355 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.15077</span> | 85.99 | 0.04042 | 0.009981 | 0.4101 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.656 | 0.6317 | 0.8672 | 1.355 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.303 | 0.03292 | 0.1430 | 0.4220 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.955 | 0.2207 | -0.1874 | -1.542 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3581 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 25</span>| 752.14731 | 0.9893 | -0.9780 | -1.007 | -1.009 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6389 | -0.9801 | -0.9200 | -0.7014 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7873 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.14731 | 86.07 | -3.209 | -4.607 | -0.3637 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.659 | 0.6316 | 0.8673 | 1.356 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.14731</span> | 86.07 | 0.04042 | 0.009980 | 0.4101 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.659 | 0.6316 | 0.8673 | 1.356 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.764 | 0.02806 | 0.1473 | 0.4277 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.749 | 0.2865 | -0.1727 | -1.510 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3572 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 26</span>| 752.14299 | 0.9884 | -0.9780 | -1.007 | -1.010 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6388 | -0.9801 | -0.9198 | -0.7000 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7876 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.14299 | 85.99 | -3.209 | -4.607 | -0.3641 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.659 | 0.6316 | 0.8675 | 1.358 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.14299</span> | 85.99 | 0.04041 | 0.009978 | 0.4100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.659 | 0.6316 | 0.8675 | 1.358 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.130 | 0.03192 | 0.1311 | 0.4194 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.750 | 0.2064 | -0.1542 | -1.466 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3587 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 27</span>| 752.13982 | 0.9893 | -0.9781 | -1.008 | -1.010 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6374 | -0.9803 | -0.9196 | -0.6987 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7873 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.13982 | 86.07 | -3.209 | -4.608 | -0.3642 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.662 | 0.6315 | 0.8676 | 1.359 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.13982</span> | 86.07 | 0.04041 | 0.009977 | 0.4099 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.662 | 0.6315 | 0.8676 | 1.359 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.635 | 0.02760 | 0.1350 | 0.4248 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.550 | 0.2683 | -0.1407 | -1.433 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3557 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 28</span>| 752.13580 | 0.9884 | -0.9782 | -1.008 | -1.012 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6373 | -0.9803 | -0.9194 | -0.6973 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7876 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.1358 | 85.99 | -3.209 | -4.608 | -0.3647 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.662 | 0.6315 | 0.8678 | 1.361 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.1358</span> | 85.99 | 0.04041 | 0.009975 | 0.4098 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.662 | 0.6315 | 0.8678 | 1.361 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.9657 | 0.03147 | 0.1207 | 0.4166 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.557 | 0.1931 | -0.1227 | -1.391 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3574 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 29</span>| 752.13295 | 0.9893 | -0.9782 | -1.008 | -1.012 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6359 | -0.9805 | -0.9193 | -0.6961 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7873 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.13295 | 86.07 | -3.209 | -4.608 | -0.3648 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.665 | 0.6314 | 0.8679 | 1.362 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.13295</span> | 86.07 | 0.04041 | 0.009973 | 0.4098 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.665 | 0.6314 | 0.8679 | 1.362 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.554 | 0.02702 | 0.1245 | 0.4220 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.357 | 0.2511 | -0.1114 | -1.356 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3512 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 30</span>| 752.12919 | 0.9885 | -0.9783 | -1.008 | -1.014 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6359 | -0.9804 | -0.9191 | -0.6947 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7876 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.12919 | 86.00 | -3.209 | -4.608 | -0.3653 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.665 | 0.6314 | 0.8681 | 1.364 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.12919</span> | 86.00 | 0.04040 | 0.009972 | 0.4097 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.665 | 0.6314 | 0.8681 | 1.364 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.8077 | 0.03076 | 0.1104 | 0.4140 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.370 | 0.1799 | -0.09417 | -1.307 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3529 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 31</span>| 752.12656 | 0.9893 | -0.9783 | -1.008 | -1.014 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6345 | -0.9806 | -0.9190 | -0.6934 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7872 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.12656 | 86.07 | -3.209 | -4.608 | -0.3654 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.668 | 0.6313 | 0.8682 | 1.365 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.12656</span> | 86.07 | 0.04040 | 0.009970 | 0.4096 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.668 | 0.6313 | 0.8682 | 1.365 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.375 | 0.02651 | 0.1140 | 0.4191 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.173 | 0.2330 | -0.08481 | -1.281 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3435 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 32</span>| 752.12310 | 0.9885 | -0.9784 | -1.008 | -1.016 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6345 | -0.9806 | -0.9188 | -0.6922 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7875 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.1231 | 86.00 | -3.209 | -4.608 | -0.3659 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.668 | 0.6313 | 0.8684 | 1.367 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.1231</span> | 86.00 | 0.04040 | 0.009969 | 0.4095 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.668 | 0.6313 | 0.8684 | 1.367 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.6515 | 0.02994 | 0.1012 | 0.4113 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.192 | 0.1669 | -0.06829 | -1.233 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3455 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 33</span>| 752.12055 | 0.9892 | -0.9784 | -1.008 | -1.016 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6332 | -0.9808 | -0.9187 | -0.6908 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7871 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.12055 | 86.06 | -3.209 | -4.608 | -0.3661 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.671 | 0.6312 | 0.8685 | 1.368 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.12055</span> | 86.06 | 0.04040 | 0.009968 | 0.4095 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.671 | 0.6312 | 0.8685 | 1.368 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.998 | 0.02610 | 0.1041 | 0.4159 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.002 | 0.2127 | -0.06061 | -1.206 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3333 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 34</span>| 752.11747 | 0.9885 | -0.9785 | -1.009 | -1.018 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6332 | -0.9807 | -0.9185 | -0.6896 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7874 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.11747 | 86.00 | -3.209 | -4.609 | -0.3666 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.671 | 0.6312 | 0.8687 | 1.370 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.11747</span> | 86.00 | 0.04039 | 0.009966 | 0.4094 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.671 | 0.6312 | 0.8687 | 1.370 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.5772 | 0.02918 | 0.09258 | 0.4085 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.024 | 0.1535 | -0.04467 | -1.159 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3360 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 35</span>| 752.11522 | 0.9892 | -0.9785 | -1.009 | -1.018 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6319 | -0.9809 | -0.9185 | -0.6881 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7870 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.11522 | 86.06 | -3.209 | -4.609 | -0.3668 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.674 | 0.6311 | 0.8687 | 1.371 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.11522</span> | 86.06 | 0.04039 | 0.009965 | 0.4093 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.674 | 0.6311 | 0.8687 | 1.371 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.959 | 0.02535 | 0.09612 | 0.4130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8451 | 0.1980 | -0.03883 | -1.121 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3219 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 36</span>| 752.11234 | 0.9885 | -0.9786 | -1.009 | -1.020 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6320 | -0.9808 | -0.9183 | -0.6870 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7872 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.11234 | 86.00 | -3.209 | -4.609 | -0.3673 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.673 | 0.6311 | 0.8689 | 1.373 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.11234</span> | 86.00 | 0.04039 | 0.009964 | 0.4092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.673 | 0.6311 | 0.8689 | 1.373 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.065 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.5042 | 0.02791 | 0.08363 | 0.4056 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8741 | 0.1402 | -0.02542 | -1.088 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3257 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 37</span>| 752.11033 | 0.9892 | -0.9787 | -1.009 | -1.020 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6308 | -0.9810 | -0.9182 | -0.6855 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7868 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.11033 | 86.06 | -3.209 | -4.609 | -0.3675 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.676 | 0.6310 | 0.8689 | 1.374 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.11033</span> | 86.06 | 0.04039 | 0.009963 | 0.4091 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.676 | 0.6310 | 0.8689 | 1.374 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.874 | 0.02465 | 0.08719 | 0.4100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7032 | 0.1835 | -0.01978 | -1.047 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3084 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 38</span>| 752.10764 | 0.9885 | -0.9787 | -1.009 | -1.022 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6309 | -0.9810 | -0.9181 | -0.6844 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7870 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.10764 | 86.00 | -3.209 | -4.609 | -0.3681 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.676 | 0.6310 | 0.8691 | 1.376 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.10764</span> | 86.00 | 0.04038 | 0.009962 | 0.4090 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.676 | 0.6310 | 0.8691 | 1.376 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.4131 | 0.02699 | 0.07721 | 0.4026 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7354 | 0.1282 | -0.007503 | -1.011 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3125 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 39</span>| 752.10572 | 0.9892 | -0.9788 | -1.009 | -1.023 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6298 | -0.9812 | -0.9181 | -0.6829 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7865 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.10572 | 86.06 | -3.209 | -4.609 | -0.3683 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.678 | 0.6309 | 0.8691 | 1.377 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.10572</span> | 86.06 | 0.04038 | 0.009960 | 0.4090 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.678 | 0.6309 | 0.8691 | 1.377 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.580 | 0.02411 | 0.07834 | 0.4067 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5755 | 0.1666 | -0.003596 | -0.9604 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2924 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 40</span>| 752.10333 | 0.9885 | -0.9789 | -1.009 | -1.024 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6300 | -0.9811 | -0.9179 | -0.6819 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7867 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.10333 | 86.00 | -3.209 | -4.609 | -0.3688 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.678 | 0.6309 | 0.8692 | 1.378 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.10333</span> | 86.00 | 0.04038 | 0.009959 | 0.4088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.678 | 0.6309 | 0.8692 | 1.378 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.3772 | 0.02648 | 0.06875 | 0.3997 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6082 | 0.1162 | 0.008208 | -0.9328 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2962 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 41</span>| 752.10169 | 0.9892 | -0.9789 | -1.009 | -1.025 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6289 | -0.9813 | -0.9179 | -0.6803 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7862 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.10169 | 86.06 | -3.209 | -4.609 | -0.3691 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.680 | 0.6308 | 0.8692 | 1.380 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.10169</span> | 86.06 | 0.04038 | 0.009958 | 0.4088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.680 | 0.6308 | 0.8692 | 1.380 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.644 | 0.02338 | 0.07127 | 0.4037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4618 | 0.1554 | 0.009391 | -0.8908 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2755 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 42</span>| 752.09938 | 0.9886 | -0.9790 | -1.009 | -1.027 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6291 | -0.9812 | -0.9178 | -0.6794 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7864 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.09938 | 86.00 | -3.210 | -4.609 | -0.3697 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.680 | 0.6308 | 0.8693 | 1.381 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.09938</span> | 86.00 | 0.04037 | 0.009958 | 0.4086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.680 | 0.6308 | 0.8693 | 1.381 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.2627 | 0.02548 | 0.06256 | 0.3967 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4955 | 0.1055 | 0.02027 | -0.8653 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2789 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 43</span>| 752.09757 | 0.9890 | -0.9791 | -1.010 | -1.028 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6281 | -0.9814 | -0.9178 | -0.6778 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7859 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.09757 | 86.05 | -3.210 | -4.610 | -0.3699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.682 | 0.6307 | 0.8693 | 1.383 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.067 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.09757</span> | 86.05 | 0.04037 | 0.009956 | 0.4086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.682 | 0.6307 | 0.8693 | 1.383 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.067 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.867 | 0.02296 | 0.06369 | 0.3997 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3645 | 0.1327 | 0.01894 | -0.8216 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2549 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 44</span>| 752.09570 | 0.9886 | -0.9791 | -1.010 | -1.030 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6283 | -0.9814 | -0.9177 | -0.6770 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7861 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.0957 | 86.00 | -3.210 | -4.610 | -0.3705 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.681 | 0.6307 | 0.8694 | 1.384 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.0957</span> | 86.00 | 0.04037 | 0.009956 | 0.4084 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.681 | 0.6307 | 0.8694 | 1.384 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.066 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.2846 | 0.02474 | 0.05675 | 0.3935 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3960 | 0.09353 | 0.02976 | -0.7961 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2595 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 45</span>| 752.09434 | 0.9891 | -0.9792 | -1.010 | -1.030 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6275 | -0.9816 | -0.9177 | -0.6754 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7856 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.09434 | 86.05 | -3.210 | -4.610 | -0.3708 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.683 | 0.6306 | 0.8694 | 1.386 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.067 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.09434</span> | 86.05 | 0.04037 | 0.009955 | 0.4083 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.683 | 0.6306 | 0.8694 | 1.386 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.067 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.348 | 0.02147 | 0.05816 | 0.3967 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2833 | 0.1286 | 0.02562 | -0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2380 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 46</span>| 752.09236 | 0.9886 | -0.9793 | -1.010 | -1.032 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6277 | -0.9815 | -0.9176 | -0.6746 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7858 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.09236 | 86.01 | -3.210 | -4.610 | -0.3715 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.683 | 0.6306 | 0.8695 | 1.387 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.067 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.09236</span> | 86.01 | 0.04036 | 0.009954 | 0.4082 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.683 | 0.6306 | 0.8695 | 1.387 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.067 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.1856 | 0.02378 | 0.05144 | 0.3902 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3147 | 0.08386 | 0.03545 | -0.7433 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2408 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 47</span>| 752.09077 | 0.9890 | -0.9793 | -1.010 | -1.033 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6269 | -0.9817 | -0.9177 | -0.6729 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7852 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.09077 | 86.04 | -3.210 | -4.610 | -0.3717 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.684 | 0.6305 | 0.8694 | 1.389 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.067 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.09077</span> | 86.04 | 0.04036 | 0.009953 | 0.4081 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.684 | 0.6305 | 0.8694 | 1.389 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.067 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 48</span>| 752.08937 | 0.9892 | -0.9795 | -1.010 | -1.036 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6267 | -0.9818 | -0.9176 | -0.6714 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7852 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.08937 | 86.06 | -3.210 | -4.610 | -0.3725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.685 | 0.6304 | 0.8695 | 1.391 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.067 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.08937</span> | 86.06 | 0.04036 | 0.009952 | 0.4079 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.685 | 0.6304 | 0.8695 | 1.391 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.067 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.945 | 0.01952 | 0.05064 | 0.3906 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1866 | 0.1233 | 0.03740 | -0.6554 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2138 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 49</span>| 752.08593 | 0.9886 | -0.9796 | -1.010 | -1.040 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6271 | -0.9817 | -0.9174 | -0.6701 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7856 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.08593 | 86.01 | -3.210 | -4.610 | -0.3740 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.684 | 0.6305 | 0.8697 | 1.392 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.067 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.08593</span> | 86.01 | 0.04035 | 0.009951 | 0.4076 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.684 | 0.6305 | 0.8697 | 1.392 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.067 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.04707 | 0.02143 | 0.04311 | 0.3795 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2514 | 0.07631 | 0.05739 | -0.6184 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2313 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 50</span>| 752.08243 | 0.9889 | -0.9798 | -1.010 | -1.042 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6256 | -0.9821 | -0.9177 | -0.6665 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7842 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.08243 | 86.03 | -3.210 | -4.610 | -0.3748 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.687 | 0.6302 | 0.8694 | 1.396 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.068 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.08243</span> | 86.03 | 0.04034 | 0.009949 | 0.4074 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.687 | 0.6302 | 0.8694 | 1.396 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.068 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 51</span>| 752.07616 | 0.9895 | -0.9803 | -1.011 | -1.054 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6231 | -0.9827 | -0.9181 | -0.6582 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7817 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.07616 | 86.08 | -3.211 | -4.611 | -0.3786 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.693 | 0.6298 | 0.8690 | 1.406 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.071 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.07616</span> | 86.08 | 0.04032 | 0.009942 | 0.4065 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.693 | 0.6298 | 0.8690 | 1.406 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.071 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.128 | 0.01286 | 0.03023 | 0.3726 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2708 | 0.07184 | -0.02487 | -0.2959 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.03882 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 52</span>| 752.06706 | 0.9888 | -0.9810 | -1.011 | -1.073 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6241 | -0.9834 | -0.9174 | -0.6562 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7830 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.06706 | 86.03 | -3.212 | -4.611 | -0.3848 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.690 | 0.6293 | 0.8696 | 1.408 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.069 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.06706</span> | 86.03 | 0.04030 | 0.009938 | 0.4050 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.690 | 0.6293 | 0.8696 | 1.408 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.069 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 53</span>| 752.05726 | 0.9892 | -0.9821 | -1.012 | -1.106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6257 | -0.9847 | -0.9162 | -0.6528 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7853 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.05726 | 86.06 | -3.213 | -4.612 | -0.3958 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.687 | 0.6284 | 0.8707 | 1.412 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.067 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.05726</span> | 86.06 | 0.04025 | 0.009929 | 0.4023 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.687 | 0.6284 | 0.8707 | 1.412 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.067 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 54</span>| 752.04392 | 0.9898 | -0.9854 | -1.015 | -1.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6305 | -0.9883 | -0.9128 | -0.6430 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7918 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.04392 | 86.11 | -3.216 | -4.615 | -0.4269 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.677 | 0.6259 | 0.8738 | 1.423 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.061 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.04392</span> | 86.11 | 0.04012 | 0.009906 | 0.3949 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.677 | 0.6259 | 0.8738 | 1.423 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.061 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.566 | -0.02004 | 0.02472 | 0.1678 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6767 | -0.003606 | 0.4773 | 0.08205 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6933 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 55</span>| 752.05860 | 0.9880 | -0.9900 | -1.027 | -1.486 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6186 | -0.9338 | -0.9168 | -0.6653 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7443 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.0586 | 85.96 | -3.221 | -4.627 | -0.5212 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.702 | 0.6640 | 0.8702 | 1.398 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.0586</span> | 85.96 | 0.03993 | 0.009780 | 0.3726 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.702 | 0.6640 | 0.8702 | 1.398 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 56</span>| 752.02137 | 0.9885 | -0.9874 | -1.020 | -1.325 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6252 | -0.9645 | -0.9146 | -0.6528 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7710 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.02137 | 86.00 | -3.218 | -4.620 | -0.4681 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.688 | 0.6425 | 0.8722 | 1.412 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.081 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.02137</span> | 86.00 | 0.04004 | 0.009850 | 0.3851 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.688 | 0.6425 | 0.8722 | 1.412 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.081 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.728 | -0.02729 | 0.08518 | 0.04185 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2367 | 0.4063 | 0.2432 | 0.01436 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.07563 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 57</span>| 752.06656 | 0.9886 | -0.9792 | -1.053 | -1.433 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6165 | -1.020 | -0.9133 | -0.6801 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7607 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.06656 | 86.01 | -3.210 | -4.653 | -0.5037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.707 | 0.6037 | 0.8734 | 1.380 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.091 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.06656</span> | 86.01 | 0.04036 | 0.009533 | 0.3767 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.707 | 0.6037 | 0.8734 | 1.380 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.091 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 58</span>| 752.02137 | 0.9885 | -0.9874 | -1.020 | -1.325 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6252 | -0.9645 | -0.9146 | -0.6528 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7710 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 752.02137 | 86.00 | -3.218 | -4.620 | -0.4681 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.688 | 0.6425 | 0.8722 | 1.412 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.081 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 752.02137</span> | 86.00 | 0.04004 | 0.009850 | 0.3851 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.688 | 0.6425 | 0.8722 | 1.412 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.081 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>initial ETAs were nudged; (can control by foceiControl(etaNudge=., etaNudge2=))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>ETAs were reset to zero during optimization; (Can control by foceiControl(resetEtaP=.))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>gradient problems with initial estimate and covariance; see $scaleInfo</span> +<span class="r-in"><span class="va">f_nlmixr_fomc_sfo_focei_const</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_const</span><span class="op">[</span><span class="st">"FOMC-SFO"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"focei"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="font-weight: bold;">Key:</span> U: Unscaled Parameters; X: Back-transformed parameters; G: Gill difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> F: Forward difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> C: Central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> M: Mixed forward and central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> Unscaled parameters for Omegas=chol(solve(omega));</span> +<span class="r-out co"><span class="r-pr">#></span> Diagonals are transformed, as specified by foceiControl(diagXform=)</span> +<span class="r-out co"><span class="r-pr">#></span> |-----+---------------+-----------+-----------+-----------+-----------|</span> +<span class="r-out co"><span class="r-pr">#></span> | #| Objective Fun | parent_0 | log_k_A1 |f_parent_qlogis | log_alpha |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| log_beta | sigma | o1 | o2 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| o3 | o4 | o5 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 1</span>| 494.78160 | 1.000 | -1.000 | -0.9115 | -0.8954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8491 | -0.8592 | -0.8761 | -0.8740 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8674 | -0.8694 | -0.8683 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.7816 | 94.00 | -5.400 | -1.000 | -0.2000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.600 | 0.7598 | 0.8633 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.189 | 1.089 | 1.146 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.7816</span> | 94.00 | 0.004517 | 0.2689 | 0.8187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.166 | 1.600 | 0.7598 | 0.8633 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.189 | 1.089 | 1.146 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | G| Gill Diff. | -28.01 | 1.933 | -0.2086 | 0.01492 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1687 | -59.79 | 10.74 | 9.966 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -11.82 | -8.862 | -10.52 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 2</span>| 1353.4477 | 1.400 | -1.028 | -0.9085 | -0.8956 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8467 | -0.005584 | -1.029 | -1.016 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6987 | -0.7429 | -0.7181 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 1353.4477 | 131.6 | -5.428 | -0.9970 | -0.2002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 2.283 | 0.6433 | 0.7405 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.390 | 1.227 | 1.318 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 1353.4477</span> | 131.6 | 0.004394 | 0.2695 | 0.8186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.186 | 2.283 | 0.6433 | 0.7405 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.390 | 1.227 | 1.318 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 3</span>| 504.82409 | 1.040 | -1.003 | -0.9112 | -0.8954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8489 | -0.7738 | -0.8914 | -0.8882 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8506 | -0.8568 | -0.8533 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 504.82409 | 97.76 | -5.403 | -0.9997 | -0.2000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.668 | 0.7482 | 0.8511 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.209 | 1.103 | 1.163 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 504.82409</span> | 97.76 | 0.004504 | 0.2690 | 0.8187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.168 | 1.668 | 0.7482 | 0.8511 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.209 | 1.103 | 1.163 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 4</span>| 494.10898 | 1.008 | -1.001 | -0.9114 | -0.8954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8490 | -0.8416 | -0.8792 | -0.8769 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8640 | -0.8668 | -0.8652 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.10898 | 94.77 | -5.401 | -0.9999 | -0.2000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.614 | 0.7574 | 0.8608 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.193 | 1.092 | 1.149 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.10898</span> | 94.77 | 0.004514 | 0.2690 | 0.8187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.167 | 1.614 | 0.7574 | 0.8608 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.193 | 1.092 | 1.149 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 147.0 | 1.955 | -0.08761 | 0.06834 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.05948 | -55.61 | 11.89 | 8.304 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -12.01 | -8.510 | -10.24 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 5</span>| 492.58255 | 0.9992 | -1.001 | -0.9114 | -0.8954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8490 | -0.8245 | -0.8825 | -0.8797 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8605 | -0.8643 | -0.8621 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 492.58255 | 93.93 | -5.401 | -0.9999 | -0.2000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.628 | 0.7550 | 0.8584 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.197 | 1.095 | 1.153 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 492.58255</span> | 93.93 | 0.004511 | 0.2690 | 0.8187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.167 | 1.628 | 0.7550 | 0.8584 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.197 | 1.095 | 1.153 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -43.22 | 1.882 | -0.2206 | -0.004719 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1970 | -51.78 | 10.22 | 6.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -11.81 | -8.346 | -10.04 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 6</span>| 491.66702 | 1.006 | -1.002 | -0.9113 | -0.8954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8490 | -0.8063 | -0.8860 | -0.8822 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8565 | -0.8614 | -0.8588 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 491.66702 | 94.52 | -5.402 | -0.9998 | -0.2000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.642 | 0.7523 | 0.8562 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.202 | 1.098 | 1.157 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 491.66702</span> | 94.52 | 0.004509 | 0.2690 | 0.8187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.167 | 1.642 | 0.7523 | 0.8562 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.202 | 1.098 | 1.157 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 87.79 | 1.893 | -0.1269 | 0.04418 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.01699 | -47.85 | 10.34 | 7.758 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -11.67 | -8.213 | -9.916 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 7</span>| 490.57489 | 0.9987 | -1.002 | -0.9112 | -0.8954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8489 | -0.7885 | -0.8895 | -0.8851 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8525 | -0.8586 | -0.8553 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 490.57489 | 93.88 | -5.402 | -0.9998 | -0.2000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.657 | 0.7496 | 0.8537 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.207 | 1.101 | 1.161 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 490.57489</span> | 93.88 | 0.004506 | 0.2690 | 0.8187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.168 | 1.657 | 0.7496 | 0.8537 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.207 | 1.101 | 1.161 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -52.56 | 1.834 | -0.2285 | -0.01046 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2159 | -44.44 | 9.379 | 7.248 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -11.47 | -8.044 | -9.710 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 8</span>| 489.67804 | 1.004 | -1.003 | -0.9112 | -0.8954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8489 | -0.7706 | -0.8932 | -0.8884 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8482 | -0.8554 | -0.8516 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 489.67804 | 94.42 | -5.403 | -0.9997 | -0.2000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.671 | 0.7468 | 0.8509 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.212 | 1.105 | 1.165 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 489.67804</span> | 94.42 | 0.004503 | 0.2690 | 0.8187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.168 | 1.671 | 0.7468 | 0.8509 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.212 | 1.105 | 1.165 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 63.10 | 1.841 | -0.1396 | 0.03713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.05177 | -40.65 | 9.345 | 6.018 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -11.29 | -7.879 | -9.567 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 9</span>| 488.80457 | 0.9984 | -1.004 | -0.9111 | -0.8954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8488 | -0.7529 | -0.8970 | -0.8913 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8435 | -0.8521 | -0.8475 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 488.80457 | 93.85 | -5.404 | -0.9996 | -0.2000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.685 | 0.7439 | 0.8484 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.218 | 1.108 | 1.170 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 488.80457</span> | 93.85 | 0.004499 | 0.2690 | 0.8187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.168 | 1.685 | 0.7439 | 0.8484 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.218 | 1.108 | 1.170 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -56.52 | 1.788 | -0.2313 | -0.01570 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2287 | -37.43 | 8.740 | 5.512 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -11.08 | -7.680 | -9.353 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 10</span>| 487.98244 | 1.004 | -1.005 | -0.9110 | -0.8954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8487 | -0.7356 | -0.9012 | -0.8939 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8380 | -0.8482 | -0.8428 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 487.98244 | 94.36 | -5.405 | -0.9995 | -0.2000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.699 | 0.7407 | 0.8461 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.224 | 1.112 | 1.175 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 487.98244</span> | 94.36 | 0.004495 | 0.2690 | 0.8187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.169 | 1.699 | 0.7407 | 0.8461 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.224 | 1.112 | 1.175 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 49.57 | 1.794 | -0.1466 | 0.03517 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07178 | -34.12 | 8.494 | 6.684 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -10.82 | -7.482 | -9.140 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 11</span>| 487.23587 | 0.9987 | -1.006 | -0.9109 | -0.8954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8487 | -0.7192 | -0.9058 | -0.8980 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8316 | -0.8438 | -0.8374 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 487.23587 | 93.88 | -5.406 | -0.9994 | -0.2001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.712 | 0.7372 | 0.8426 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.232 | 1.117 | 1.181 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 487.23587</span> | 93.88 | 0.004490 | 0.2691 | 0.8187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.170 | 1.712 | 0.7372 | 0.8426 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.232 | 1.117 | 1.181 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -49.22 | 1.745 | -0.2274 | -0.009194 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2301 | -31.48 | 7.992 | 6.132 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -10.64 | -7.269 | -8.903 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 12</span>| 486.53337 | 1.004 | -1.007 | -0.9107 | -0.8954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8485 | -0.7047 | -0.9109 | -0.9037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8240 | -0.8386 | -0.8310 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 486.53337 | 94.34 | -5.407 | -0.9993 | -0.2001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 1.724 | 0.7334 | 0.8376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.241 | 1.123 | 1.189 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 486.53337</span> | 94.34 | 0.004484 | 0.2691 | 0.8187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.171 | 1.724 | 0.7334 | 0.8376 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.241 | 1.123 | 1.189 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 43.47 | 1.742 | -0.1424 | 0.02918 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07089 | -28.76 | 7.629 | 4.806 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -10.24 | -6.953 | -8.584 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 13</span>| 485.91669 | 0.9989 | -1.009 | -0.9105 | -0.8955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8484 | -0.6920 | -0.9165 | -0.9072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8145 | -0.8325 | -0.8231 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 485.91669 | 93.90 | -5.409 | -0.9991 | -0.2001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 1.734 | 0.7291 | 0.8346 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.252 | 1.130 | 1.198 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 485.91669</span> | 93.90 | 0.004476 | 0.2691 | 0.8187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.172 | 1.734 | 0.7291 | 0.8346 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.252 | 1.130 | 1.198 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -44.30 | 1.699 | -0.2182 | 0.001936 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2284 | -26.86 | 7.286 | 5.487 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -9.898 | -6.659 | -8.234 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 14</span>| 485.33976 | 1.003 | -1.011 | -0.9103 | -0.8955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8481 | -0.6819 | -0.9228 | -0.9110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8035 | -0.8257 | -0.8143 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 485.33976 | 94.29 | -5.411 | -0.9988 | -0.2001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 1.742 | 0.7243 | 0.8314 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.265 | 1.137 | 1.208 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 485.33976</span> | 94.29 | 0.004467 | 0.2692 | 0.8186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.174 | 1.742 | 0.7243 | 0.8314 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.265 | 1.137 | 1.208 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 15</span>| 484.77317 | 1.003 | -1.014 | -0.9100 | -0.8956 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8479 | -0.6718 | -0.9302 | -0.9153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7902 | -0.8175 | -0.8035 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 484.77317 | 94.32 | -5.414 | -0.9986 | -0.2002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 1.750 | 0.7187 | 0.8276 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.281 | 1.146 | 1.220 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 484.77317</span> | 94.32 | 0.004455 | 0.2692 | 0.8186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.176 | 1.750 | 0.7187 | 0.8276 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.281 | 1.146 | 1.220 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 16</span>| 483.17588 | 1.004 | -1.023 | -0.9091 | -0.8958 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8469 | -0.6384 | -0.9549 | -0.9296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7463 | -0.7903 | -0.7681 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 483.17588 | 94.41 | -5.423 | -0.9976 | -0.2004 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.777 | 0.6999 | 0.8153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.333 | 1.176 | 1.261 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 483.17588</span> | 94.41 | 0.004415 | 0.2694 | 0.8184 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.184 | 1.777 | 0.6999 | 0.8153 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.333 | 1.176 | 1.261 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 17</span>| 481.21481 | 1.006 | -1.040 | -0.9072 | -0.8961 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8451 | -0.5721 | -1.004 | -0.9579 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6592 | -0.7365 | -0.6977 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 481.21481 | 94.58 | -5.440 | -0.9958 | -0.2008 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.104 | 1.830 | 0.6628 | 0.7909 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.437 | 1.234 | 1.341 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 481.21481</span> | 94.58 | 0.004338 | 0.2698 | 0.8181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.199 | 1.830 | 0.6628 | 0.7909 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.437 | 1.234 | 1.341 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 62.86 | 1.476 | 0.06730 | 0.05792 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1123 | -8.977 | 1.055 | 2.914 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -3.044 | -1.094 | -2.299 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 18</span>| 481.29476 | 1.000 | -1.145 | -0.9129 | -0.8997 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8485 | -0.5378 | -0.8985 | -1.168 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6228 | -0.8149 | -0.6969 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 481.29476 | 94.03 | -5.545 | -1.001 | -0.2043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 1.857 | 0.7428 | 0.6099 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.480 | 1.149 | 1.342 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 481.29476</span> | 94.03 | 0.003907 | 0.2687 | 0.8152 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.171 | 1.857 | 0.7428 | 0.6099 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.480 | 1.149 | 1.342 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 19</span>| 480.77138 | 1.000 | -1.090 | -0.9099 | -0.8978 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8467 | -0.5555 | -0.9542 | -1.057 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6419 | -0.7733 | -0.6972 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.77138 | 94.01 | -5.490 | -0.9984 | -0.2025 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.843 | 0.7004 | 0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.457 | 1.194 | 1.342 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.77138</span> | 94.01 | 0.004129 | 0.2693 | 0.8167 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.186 | 1.843 | 0.7004 | 0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.457 | 1.194 | 1.342 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -25.72 | 1.151 | 0.08772 | -0.007897 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07232 | -6.930 | 3.330 | -2.491 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.626 | -3.111 | -2.500 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 20</span>| 480.61717 | 1.001 | -1.203 | -0.9227 | -0.9002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8503 | -0.5418 | -0.9405 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6281 | -0.7705 | -0.6908 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.61717 | 94.09 | -5.603 | -1.011 | -0.2049 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.854 | 0.7108 | 0.7537 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.474 | 1.197 | 1.349 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.61717</span> | 94.09 | 0.003688 | 0.2667 | 0.8147 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.156 | 1.854 | 0.7108 | 0.7537 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.474 | 1.197 | 1.349 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -10.61 | 0.9224 | -0.5881 | -0.06621 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1838 | -5.929 | 3.775 | 2.798 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.936 | -2.993 | -2.208 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 21</span>| 480.72130 | 1.009 | -1.314 | -0.9169 | -0.9003 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8494 | -0.5516 | -0.9873 | -1.003 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6340 | -0.7292 | -0.6819 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.7213 | 94.81 | -5.714 | -1.005 | -0.2049 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.846 | 0.6753 | 0.7523 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.467 | 1.242 | 1.359 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.7213</span> | 94.81 | 0.003299 | 0.2679 | 0.8147 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.163 | 1.846 | 0.6753 | 0.7523 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.467 | 1.242 | 1.359 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 22</span>| 480.86254 | 1.009 | -1.247 | -0.9202 | -0.9002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8499 | -0.5429 | -0.9605 | -1.003 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6295 | -0.7530 | -0.6863 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.86254 | 94.84 | -5.647 | -1.009 | -0.2048 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.853 | 0.6957 | 0.7520 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.472 | 1.216 | 1.354 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.86254</span> | 94.84 | 0.003530 | 0.2672 | 0.8148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.160 | 1.853 | 0.6957 | 0.7520 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.472 | 1.216 | 1.354 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 23</span>| 480.98412 | 1.009 | -1.209 | -0.9220 | -0.9002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8501 | -0.5381 | -0.9458 | -1.003 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6270 | -0.7661 | -0.6887 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.98412 | 94.85 | -5.609 | -1.010 | -0.2048 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.857 | 0.7069 | 0.7519 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.475 | 1.202 | 1.352 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.98412</span> | 94.85 | 0.003664 | 0.2669 | 0.8148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.158 | 1.857 | 0.7069 | 0.7519 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.475 | 1.202 | 1.352 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 24</span>| 480.60990 | 1.003 | -1.203 | -0.9226 | -0.9002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8503 | -0.5410 | -0.9411 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6278 | -0.7701 | -0.6905 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.6099 | 94.24 | -5.603 | -1.011 | -0.2049 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.855 | 0.7104 | 0.7534 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.474 | 1.198 | 1.350 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.6099</span> | 94.24 | 0.003688 | 0.2668 | 0.8148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.156 | 1.855 | 0.7104 | 0.7534 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.474 | 1.198 | 1.350 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 15.29 | 0.9278 | -0.5289 | -0.04762 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1043 | -5.468 | 3.876 | 0.6273 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.897 | -2.941 | -2.183 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 25</span>| 480.59557 | 1.001 | -1.204 | -0.9225 | -0.9002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8503 | -0.5407 | -0.9419 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6277 | -0.7694 | -0.6902 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.59557 | 94.13 | -5.604 | -1.011 | -0.2049 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.855 | 0.7098 | 0.7533 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.474 | 1.198 | 1.350 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.59557</span> | 94.13 | 0.003683 | 0.2668 | 0.8148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.157 | 1.855 | 0.7098 | 0.7533 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.474 | 1.198 | 1.350 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.733 | 0.9212 | -0.5619 | -0.05855 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1664 | -5.388 | 3.833 | 0.5854 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.924 | -2.927 | -2.102 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 26</span>| 480.58581 | 1.002 | -1.204 | -0.9224 | -0.9002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8502 | -0.5395 | -0.9428 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6273 | -0.7688 | -0.6897 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.58581 | 94.23 | -5.604 | -1.011 | -0.2048 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.856 | 0.7092 | 0.7532 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.475 | 1.199 | 1.351 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.58581</span> | 94.23 | 0.003683 | 0.2668 | 0.8148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.157 | 1.856 | 0.7092 | 0.7532 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.475 | 1.199 | 1.351 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 12.31 | 0.9226 | -0.5246 | -0.05019 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1134 | -5.293 | 3.771 | 0.5822 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.938 | -2.904 | -2.175 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 27</span>| 480.57360 | 1.001 | -1.205 | -0.9222 | -0.9002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8502 | -0.5392 | -0.9437 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6271 | -0.7681 | -0.6894 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.5736 | 94.13 | -5.605 | -1.011 | -0.2048 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.856 | 0.7085 | 0.7532 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.475 | 1.200 | 1.351 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.5736</span> | 94.13 | 0.003678 | 0.2668 | 0.8148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.157 | 1.856 | 0.7085 | 0.7532 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.475 | 1.200 | 1.351 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.864 | 0.9151 | -0.5515 | -0.06112 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1679 | -5.184 | 3.617 | 0.5746 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.832 | -2.849 | -2.141 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 28</span>| 480.56429 | 1.002 | -1.206 | -0.9220 | -0.9002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8502 | -0.5382 | -0.9446 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6268 | -0.7674 | -0.6889 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.56429 | 94.23 | -5.606 | -1.011 | -0.2048 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.857 | 0.7078 | 0.7531 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.475 | 1.201 | 1.351 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.56429</span> | 94.23 | 0.003676 | 0.2669 | 0.8148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.158 | 1.857 | 0.7078 | 0.7531 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.475 | 1.201 | 1.351 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 12.18 | 0.9169 | -0.5105 | -0.05061 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1125 | -5.131 | 3.532 | 0.5638 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.931 | -2.821 | -2.132 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 29</span>| 480.55246 | 1.001 | -1.207 | -0.9218 | -0.9002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8501 | -0.5380 | -0.9454 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6266 | -0.7667 | -0.6886 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.55246 | 94.13 | -5.607 | -1.010 | -0.2048 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.857 | 0.7071 | 0.7532 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.476 | 1.201 | 1.352 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.55246</span> | 94.13 | 0.003672 | 0.2669 | 0.8148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.158 | 1.857 | 0.7071 | 0.7532 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.476 | 1.201 | 1.352 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.480 | 0.9098 | -0.5353 | -0.06055 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1647 | -5.053 | 3.625 | 0.5654 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.860 | -2.782 | -2.112 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 30</span>| 480.54335 | 1.002 | -1.207 | -0.9217 | -0.9002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8501 | -0.5368 | -0.9463 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6262 | -0.7660 | -0.6881 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.54335 | 94.23 | -5.607 | -1.010 | -0.2048 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.858 | 0.7065 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.476 | 1.202 | 1.352 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.54335</span> | 94.23 | 0.003671 | 0.2669 | 0.8148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.158 | 1.858 | 0.7065 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.476 | 1.202 | 1.352 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 12.09 | 0.9120 | -0.4955 | -0.05014 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1107 | -4.912 | 3.583 | 0.5835 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.814 | -2.702 | -2.057 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 31</span>| 480.53185 | 1.001 | -1.209 | -0.9215 | -0.9002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8500 | -0.5366 | -0.9472 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6260 | -0.7654 | -0.6878 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.53185 | 94.13 | -5.609 | -1.010 | -0.2048 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.858 | 0.7058 | 0.7531 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.476 | 1.203 | 1.353 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.53185</span> | 94.13 | 0.003666 | 0.2670 | 0.8148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.158 | 1.858 | 0.7058 | 0.7531 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.476 | 1.203 | 1.353 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.509 | 0.9048 | -0.5214 | -0.06027 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1665 | -4.870 | 3.525 | 0.5641 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.813 | -2.699 | -2.069 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 32</span>| 480.52276 | 1.002 | -1.209 | -0.9214 | -0.9001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8500 | -0.5356 | -0.9481 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6256 | -0.7647 | -0.6873 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.52276 | 94.22 | -5.609 | -1.010 | -0.2048 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.859 | 0.7051 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 1.203 | 1.353 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.52276</span> | 94.22 | 0.003664 | 0.2670 | 0.8148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.159 | 1.859 | 0.7051 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.477 | 1.203 | 1.353 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 11.38 | 0.9060 | -0.4821 | -0.05014 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1110 | -4.747 | 3.479 | 0.5798 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.777 | -2.636 | -2.020 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 33</span>| 480.51194 | 1.001 | -1.211 | -0.9212 | -0.9001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8500 | -0.5355 | -0.9490 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6255 | -0.7641 | -0.6869 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.51194 | 94.13 | -5.611 | -1.010 | -0.2048 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.859 | 0.7044 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 1.204 | 1.354 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.51194</span> | 94.13 | 0.003659 | 0.2670 | 0.8148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.159 | 1.859 | 0.7044 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.477 | 1.204 | 1.354 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.485 | 0.8991 | -0.5064 | -0.06148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1643 | -4.758 | 3.403 | 0.5432 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.772 | -2.633 | -2.022 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 34</span>| 480.50302 | 1.002 | -1.211 | -0.9210 | -0.9001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8499 | -0.5345 | -0.9500 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6251 | -0.7633 | -0.6864 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.50302 | 94.22 | -5.611 | -1.010 | -0.2047 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.860 | 0.7037 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 1.205 | 1.354 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.50302</span> | 94.22 | 0.003656 | 0.2671 | 0.8149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.159 | 1.860 | 0.7037 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.477 | 1.205 | 1.354 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 10.83 | 0.8997 | -0.4680 | -0.05021 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1106 | -4.703 | 3.332 | 0.5674 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.765 | -2.559 | -1.986 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 35</span>| 480.49281 | 1.001 | -1.213 | -0.9209 | -0.9001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8499 | -0.5344 | -0.9509 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6250 | -0.7627 | -0.6860 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.49281 | 94.13 | -5.613 | -1.009 | -0.2047 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.860 | 0.7030 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.478 | 1.206 | 1.355 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.49281</span> | 94.13 | 0.003652 | 0.2671 | 0.8149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.160 | 1.860 | 0.7030 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.478 | 1.206 | 1.355 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.447 | 0.8934 | -0.4900 | -0.06030 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1577 | -4.708 | 3.266 | 0.5080 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.782 | -2.544 | -1.983 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 36</span>| 480.48415 | 1.002 | -1.213 | -0.9207 | -0.9001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8498 | -0.5335 | -0.9518 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6246 | -0.7620 | -0.6855 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.48415 | 94.22 | -5.613 | -1.009 | -0.2047 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.861 | 0.7023 | 0.7528 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.478 | 1.206 | 1.355 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.48415</span> | 94.22 | 0.003649 | 0.2671 | 0.8149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.160 | 1.861 | 0.7023 | 0.7528 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.478 | 1.206 | 1.355 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 10.47 | 0.8932 | -0.4526 | -0.04997 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1093 | -4.502 | 3.250 | 0.5653 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.769 | -2.486 | -1.944 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 37</span>| 480.47437 | 1.001 | -1.215 | -0.9205 | -0.9001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8498 | -0.5334 | -0.9527 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6244 | -0.7613 | -0.6852 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.47437 | 94.13 | -5.615 | -1.009 | -0.2047 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.861 | 0.7016 | 0.7528 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.478 | 1.207 | 1.356 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.47437</span> | 94.13 | 0.003644 | 0.2672 | 0.8149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.161 | 1.861 | 0.7016 | 0.7528 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.478 | 1.207 | 1.356 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.431 | 0.8869 | -0.4735 | -0.05983 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1554 | -4.492 | 3.189 | -0.6996 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.700 | -2.467 | -1.937 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 38</span>| 480.46651 | 1.002 | -1.216 | -0.9203 | -0.9000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8497 | -0.5326 | -0.9537 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6240 | -0.7606 | -0.6847 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.46651 | 94.21 | -5.616 | -1.009 | -0.2047 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.861 | 0.7009 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.479 | 1.208 | 1.356 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.46651</span> | 94.21 | 0.003640 | 0.2672 | 0.8149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.161 | 1.861 | 0.7009 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.479 | 1.208 | 1.356 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 9.502 | 0.8860 | -0.4381 | -0.05035 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1103 | -4.453 | 3.114 | 0.5384 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.770 | -2.407 | -1.897 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 39</span>| 480.45755 | 1.001 | -1.217 | -0.9200 | -0.9000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8497 | -0.5325 | -0.9546 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6238 | -0.7600 | -0.6843 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.45755 | 94.13 | -5.617 | -1.009 | -0.2047 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.861 | 0.7002 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.479 | 1.209 | 1.357 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.45755</span> | 94.13 | 0.003635 | 0.2673 | 0.8149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.162 | 1.861 | 0.7002 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.479 | 1.209 | 1.357 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.779 | 0.8798 | -0.4544 | -0.05816 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1541 | -4.432 | 3.060 | 0.5236 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.719 | -2.365 | -1.874 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 40</span>| 480.44943 | 1.002 | -1.218 | -0.9199 | -0.9000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8496 | -0.5319 | -0.9555 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6235 | -0.7592 | -0.6838 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.44943 | 94.21 | -5.618 | -1.008 | -0.2046 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.862 | 0.6995 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.479 | 1.209 | 1.357 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.44943</span> | 94.21 | 0.003631 | 0.2673 | 0.8149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.162 | 1.862 | 0.6995 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.479 | 1.209 | 1.357 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 8.806 | 0.8785 | -0.4202 | -0.05024 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1124 | -4.289 | 3.039 | 0.5974 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.651 | -2.322 | -1.843 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 41</span>| 480.44100 | 1.001 | -1.220 | -0.9197 | -0.9000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8496 | -0.5318 | -0.9564 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6233 | -0.7586 | -0.6835 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.441 | 94.13 | -5.620 | -1.008 | -0.2046 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.862 | 0.6988 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.480 | 1.210 | 1.358 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.441</span> | 94.13 | 0.003626 | 0.2673 | 0.8150 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.162 | 1.862 | 0.6988 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.480 | 1.210 | 1.358 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.662 | 0.8724 | -0.4382 | -0.05735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1541 | -4.192 | 3.008 | 0.5718 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.633 | -2.283 | -1.828 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 42</span>| 480.43316 | 1.002 | -1.221 | -0.9195 | -0.9000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8495 | -0.5313 | -0.9573 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6230 | -0.7579 | -0.6830 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.43316 | 94.21 | -5.621 | -1.008 | -0.2046 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.862 | 0.6981 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.480 | 1.211 | 1.358 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.43316</span> | 94.21 | 0.003622 | 0.2674 | 0.8150 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.163 | 1.862 | 0.6981 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.480 | 1.211 | 1.358 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 8.374 | 0.8709 | -0.4057 | -0.04981 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1077 | -4.274 | 2.898 | 0.5670 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.709 | -2.249 | -1.806 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 43</span>| 480.42514 | 1.001 | -1.222 | -0.9194 | -0.8999 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8495 | -0.5312 | -0.9582 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6227 | -0.7573 | -0.6826 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.42514 | 94.13 | -5.622 | -1.008 | -0.2046 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.862 | 0.6974 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.480 | 1.212 | 1.359 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.42514</span> | 94.13 | 0.003617 | 0.2674 | 0.8150 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.163 | 1.862 | 0.6974 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.480 | 1.212 | 1.359 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.560 | 0.8648 | -0.4238 | -0.05673 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1505 | -4.130 | 2.894 | 0.5588 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.637 | -2.210 | -1.785 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 44</span>| 480.41757 | 1.002 | -1.223 | -0.9192 | -0.8999 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8494 | -0.5307 | -0.9591 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6223 | -0.7566 | -0.6821 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.41757 | 94.21 | -5.623 | -1.008 | -0.2046 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.863 | 0.6967 | 0.7528 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.481 | 1.212 | 1.359 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.41757</span> | 94.21 | 0.003613 | 0.2674 | 0.8150 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.164 | 1.863 | 0.6967 | 0.7528 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.481 | 1.212 | 1.359 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 8.260 | 0.8632 | -0.3905 | -0.04898 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1050 | -4.163 | 2.793 | 0.5626 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.680 | -2.170 | -1.767 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 45</span>| 480.40986 | 1.001 | -1.225 | -0.9190 | -0.8999 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8494 | -0.5306 | -0.9600 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6221 | -0.7560 | -0.6818 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.40986 | 94.13 | -5.625 | -1.008 | -0.2045 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.863 | 0.6961 | 0.7528 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.481 | 1.213 | 1.360 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.40986</span> | 94.13 | 0.003607 | 0.2675 | 0.8150 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.164 | 1.863 | 0.6961 | 0.7528 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.481 | 1.213 | 1.360 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.433 | 0.8570 | -0.4082 | -0.05598 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1439 | -4.083 | 2.776 | -0.7191 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.623 | -2.134 | -1.744 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 46</span>| 480.40309 | 1.002 | -1.226 | -0.9188 | -0.8999 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8493 | -0.5301 | -0.9609 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6217 | -0.7553 | -0.6813 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.40309 | 94.20 | -5.626 | -1.007 | -0.2045 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.863 | 0.6954 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.481 | 1.214 | 1.360 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.40309</span> | 94.20 | 0.003603 | 0.2675 | 0.8151 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.165 | 1.863 | 0.6954 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.481 | 1.214 | 1.360 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 7.640 | 0.8551 | -0.3719 | -0.04853 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1037 | -4.111 | 2.689 | 0.5674 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.653 | -2.095 | -1.726 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 47</span>| 480.39597 | 1.001 | -1.227 | -0.9185 | -0.8998 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8492 | -0.5300 | -0.9618 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6215 | -0.7547 | -0.6809 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.39597 | 94.13 | -5.627 | -1.007 | -0.2045 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.863 | 0.6947 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.482 | 1.214 | 1.361 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.39597</span> | 94.13 | 0.003598 | 0.2676 | 0.8151 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.165 | 1.863 | 0.6947 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.482 | 1.214 | 1.361 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.827 | 0.8487 | -0.3865 | -0.05558 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1453 | -3.997 | 2.662 | 0.5449 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.580 | -2.061 | -1.701 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 48</span>| 480.38900 | 1.002 | -1.229 | -0.9184 | -0.8998 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8491 | -0.5297 | -0.9626 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6211 | -0.7540 | -0.6805 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.389 | 94.20 | -5.629 | -1.007 | -0.2044 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.864 | 0.6940 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.482 | 1.215 | 1.361 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.389</span> | 94.20 | 0.003593 | 0.2676 | 0.8151 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.166 | 1.864 | 0.6940 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.482 | 1.215 | 1.361 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 7.052 | 0.8465 | -0.3544 | -0.04836 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1022 | -3.917 | 2.636 | 0.5926 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.553 | -2.027 | -1.689 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 49</span>| 480.38219 | 1.001 | -1.230 | -0.9183 | -0.8998 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8491 | -0.5296 | -0.9634 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6209 | -0.7534 | -0.6801 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.38219 | 94.13 | -5.630 | -1.007 | -0.2044 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.864 | 0.6934 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.482 | 1.216 | 1.362 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.38219</span> | 94.13 | 0.003587 | 0.2676 | 0.8151 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.166 | 1.864 | 0.6934 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.482 | 1.216 | 1.362 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.619 | 0.8406 | -0.3725 | -0.05439 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1411 | -3.915 | 2.594 | -0.6808 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.519 | -1.986 | -1.659 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 50</span>| 480.37598 | 1.002 | -1.232 | -0.9180 | -0.8998 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8490 | -0.5292 | -0.9644 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6206 | -0.7528 | -0.6796 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.37598 | 94.20 | -5.632 | -1.007 | -0.2044 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.864 | 0.6927 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.483 | 1.216 | 1.362 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.37598</span> | 94.20 | 0.003582 | 0.2677 | 0.8152 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.167 | 1.864 | 0.6927 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.483 | 1.216 | 1.362 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 6.566 | 0.8383 | -0.3380 | -0.04700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09943 | -3.949 | 2.377 | 0.5751 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.561 | -1.951 | -1.641 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 51</span>| 480.36982 | 1.001 | -1.233 | -0.9178 | -0.8997 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8489 | -0.5291 | -0.9651 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6204 | -0.7522 | -0.6792 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.36982 | 94.12 | -5.633 | -1.006 | -0.2043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.864 | 0.6922 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.483 | 1.217 | 1.363 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.36982</span> | 94.12 | 0.003577 | 0.2677 | 0.8152 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.167 | 1.864 | 0.6922 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.483 | 1.217 | 1.363 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.243 | 0.8317 | -0.3515 | -0.05392 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1358 | -3.830 | 2.493 | 0.5823 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.510 | -1.918 | -1.620 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 52</span>| 480.36331 | 1.002 | -1.235 | -0.9176 | -0.8997 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8489 | -0.5289 | -0.9659 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6201 | -0.7516 | -0.6788 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.36331 | 94.19 | -5.635 | -1.006 | -0.2043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.864 | 0.6916 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.483 | 1.218 | 1.363 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.36331</span> | 94.19 | 0.003572 | 0.2677 | 0.8152 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.168 | 1.864 | 0.6916 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.483 | 1.218 | 1.363 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.492 | 0.8288 | -0.3226 | -0.04732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09956 | -3.829 | 2.435 | 0.5676 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.517 | -1.882 | -1.604 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 53</span>| 480.35731 | 1.001 | -1.236 | -0.9175 | -0.8996 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8488 | -0.5288 | -0.9666 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6198 | -0.7510 | -0.6783 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.35731 | 94.12 | -5.636 | -1.006 | -0.2043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.864 | 0.6910 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.484 | 1.218 | 1.364 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.35731</span> | 94.12 | 0.003566 | 0.2678 | 0.8152 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.168 | 1.864 | 0.6910 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.484 | 1.218 | 1.364 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.442 | 0.8230 | -0.3401 | -0.05270 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1329 | -3.818 | 2.394 | -0.6865 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.462 | -1.826 | -1.568 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 54</span>| 480.35158 | 1.002 | -1.238 | -0.9173 | -0.8996 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8487 | -0.5286 | -0.9675 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6197 | -0.7504 | -0.6779 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.35158 | 94.19 | -5.638 | -1.006 | -0.2042 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.864 | 0.6904 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.484 | 1.219 | 1.364 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.35158</span> | 94.19 | 0.003561 | 0.2678 | 0.8153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.169 | 1.864 | 0.6904 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.484 | 1.219 | 1.364 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.119 | 0.8198 | -0.3066 | -0.04724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1005 | -3.787 | 2.338 | 0.5896 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.465 | -1.812 | -1.559 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 55</span>| 480.34603 | 1.001 | -1.239 | -0.9170 | -0.8996 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8486 | -0.5283 | -0.9683 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6195 | -0.7499 | -0.6775 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.34603 | 94.12 | -5.639 | -1.006 | -0.2042 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.865 | 0.6897 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.484 | 1.220 | 1.364 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.34603</span> | 94.12 | 0.003555 | 0.2679 | 0.8153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.170 | 1.865 | 0.6897 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.484 | 1.220 | 1.364 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.669 | 0.8137 | -0.3182 | -0.05158 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1292 | -3.845 | 2.251 | 0.5349 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.532 | -1.781 | -1.537 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 56</span>| 480.33997 | 1.002 | -1.241 | -0.9169 | -0.8995 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8486 | -0.5282 | -0.9690 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6192 | -0.7493 | -0.6772 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.33997 | 94.19 | -5.641 | -1.005 | -0.2041 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 1.865 | 0.6892 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.484 | 1.220 | 1.365 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.33997</span> | 94.19 | 0.003550 | 0.2679 | 0.8153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.170 | 1.865 | 0.6892 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.484 | 1.220 | 1.365 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.944 | 0.8109 | -0.2900 | -0.04418 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09220 | -3.817 | 2.207 | 0.5423 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.530 | -1.750 | -1.524 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 57</span>| 480.33440 | 1.001 | -1.242 | -0.9168 | -0.8995 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8485 | -0.5280 | -0.9697 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6188 | -0.7487 | -0.6768 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.3344 | 94.12 | -5.642 | -1.005 | -0.2041 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 1.865 | 0.6887 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.485 | 1.221 | 1.365 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.3344</span> | 94.12 | 0.003544 | 0.2679 | 0.8154 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.171 | 1.865 | 0.6887 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.485 | 1.221 | 1.365 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.630 | 0.8048 | -0.3070 | -0.04965 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1246 | -3.770 | 2.179 | 0.5400 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.465 | -1.710 | -1.500 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 58</span>| 480.32852 | 1.002 | -1.244 | -0.9167 | -0.8994 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8485 | -0.5278 | -0.9703 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6184 | -0.7482 | -0.6764 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.32852 | 94.19 | -5.644 | -1.005 | -0.2041 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 1.865 | 0.6882 | 0.7528 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.485 | 1.221 | 1.366 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.32852</span> | 94.19 | 0.003538 | 0.2679 | 0.8154 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.171 | 1.865 | 0.6882 | 0.7528 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.485 | 1.221 | 1.366 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.819 | 0.8018 | -0.2789 | -0.04260 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.08823 | -3.653 | 2.177 | -0.6593 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.384 | -1.678 | -1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 59</span>| 480.32382 | 1.001 | -1.246 | -0.9164 | -0.8994 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8484 | -0.5276 | -0.9711 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6183 | -0.7477 | -0.6761 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.32382 | 94.12 | -5.646 | -1.005 | -0.2040 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 1.865 | 0.6876 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.486 | 1.222 | 1.366 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.32382</span> | 94.12 | 0.003533 | 0.2680 | 0.8155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.172 | 1.865 | 0.6876 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.486 | 1.222 | 1.366 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.225 | 0.7951 | -0.2896 | -0.04843 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1194 | -3.720 | 2.091 | -0.7072 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.430 | -1.641 | -1.454 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 60</span>| 480.31902 | 1.002 | -1.247 | -0.9160 | -0.8993 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8482 | -0.5273 | -0.9719 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6182 | -0.7473 | -0.6757 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.31902 | 94.19 | -5.647 | -1.005 | -0.2039 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 1.865 | 0.6870 | 0.7531 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.486 | 1.222 | 1.367 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.31902</span> | 94.19 | 0.003527 | 0.2681 | 0.8155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.173 | 1.865 | 0.6870 | 0.7531 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.486 | 1.222 | 1.367 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.904 | 0.7922 | -0.2469 | -0.04034 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.08539 | -3.545 | 2.094 | -0.6237 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.331 | -1.619 | -1.454 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 61</span>| 480.31471 | 1.001 | -1.249 | -0.9156 | -0.8993 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8481 | -0.5271 | -0.9727 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6181 | -0.7468 | -0.6753 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.31471 | 94.12 | -5.649 | -1.004 | -0.2039 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 1.866 | 0.6864 | 0.7533 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.486 | 1.223 | 1.367 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.31471</span> | 94.12 | 0.003522 | 0.2681 | 0.8156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.174 | 1.866 | 0.6864 | 0.7533 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.486 | 1.223 | 1.367 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.295 | 0.7853 | -0.2507 | -0.04627 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1126 | -3.760 | 1.942 | -0.7288 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.482 | -1.617 | -1.436 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 62</span>| 480.31013 | 1.002 | -1.250 | -0.9152 | -0.8992 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8480 | -0.5269 | -0.9734 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6180 | -0.7464 | -0.6750 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.31013 | 94.19 | -5.650 | -1.004 | -0.2038 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 1.866 | 0.6859 | 0.7535 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.486 | 1.223 | 1.367 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.31013</span> | 94.19 | 0.003516 | 0.2682 | 0.8156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.175 | 1.866 | 0.6859 | 0.7535 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.486 | 1.223 | 1.367 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.435 | 0.7821 | -0.2118 | -0.03855 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07590 | -3.495 | 2.000 | -0.6027 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.382 | -1.576 | -1.413 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 63</span>| 480.30581 | 1.001 | -1.252 | -0.9149 | -0.8991 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8479 | -0.5266 | -0.9741 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6178 | -0.7459 | -0.6746 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.30581 | 94.12 | -5.652 | -1.003 | -0.2037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 1.866 | 0.6854 | 0.7536 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.486 | 1.224 | 1.368 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.30581</span> | 94.12 | 0.003510 | 0.2683 | 0.8157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.176 | 1.866 | 0.6854 | 0.7536 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.486 | 1.224 | 1.368 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.315 | 0.7789 | -0.2090 | -0.03720 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09944 | -3.577 | 1.911 | -0.6518 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.378 | -1.528 | -1.376 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 64</span>| 480.30125 | 1.002 | -1.254 | -0.9146 | -0.8990 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8478 | -0.5264 | -0.9748 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6176 | -0.7454 | -0.6743 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.30125 | 94.19 | -5.654 | -1.003 | -0.2037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 1.866 | 0.6848 | 0.7538 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.486 | 1.224 | 1.368 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.30125</span> | 94.19 | 0.003505 | 0.2683 | 0.8157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.177 | 1.866 | 0.6848 | 0.7538 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.486 | 1.224 | 1.368 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.353 | 0.7723 | -0.1834 | -0.03622 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07047 | -3.672 | 1.822 | -0.6713 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.445 | -1.532 | -1.389 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 65</span>| 480.29714 | 1.001 | -1.255 | -0.9143 | -0.8990 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8476 | -0.5261 | -0.9754 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6174 | -0.7450 | -0.6740 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.29714 | 94.12 | -5.655 | -1.003 | -0.2036 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 1.866 | 0.6843 | 0.7539 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.487 | 1.225 | 1.369 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.29714</span> | 94.12 | 0.003499 | 0.2684 | 0.8158 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.178 | 1.866 | 0.6843 | 0.7539 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.487 | 1.225 | 1.369 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.435 | 0.7663 | -0.1878 | -0.03986 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1019 | -3.343 | 1.893 | 0.6711 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.269 | -1.487 | -1.354 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 66</span>| 480.29215 | 1.002 | -1.257 | -0.9143 | -0.8989 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8476 | -0.5260 | -0.9760 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6172 | -0.7444 | -0.6736 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.29215 | 94.18 | -5.657 | -1.003 | -0.2036 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.867 | 0.6839 | 0.7538 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.487 | 1.226 | 1.369 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.29215</span> | 94.18 | 0.003493 | 0.2684 | 0.8158 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.179 | 1.867 | 0.6839 | 0.7538 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.487 | 1.226 | 1.369 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.161 | 0.7621 | -0.1686 | -0.03452 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06632 | -3.552 | 1.775 | 0.6057 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.379 | -1.473 | -1.364 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 67</span>| 480.28721 | 1.001 | -1.259 | -0.9145 | -0.8989 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8476 | -0.5257 | -0.9765 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6170 | -0.7439 | -0.6732 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.28721 | 94.12 | -5.659 | -1.003 | -0.2035 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.867 | 0.6836 | 0.7537 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.487 | 1.226 | 1.369 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.28721</span> | 94.12 | 0.003487 | 0.2684 | 0.8159 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.179 | 1.867 | 0.6836 | 0.7537 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.487 | 1.226 | 1.369 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.925 | 0.7584 | -0.1913 | -0.03513 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09132 | -3.418 | 1.781 | -0.6203 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.349 | -1.417 | -1.313 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 68</span>| 480.28278 | 1.002 | -1.260 | -0.9144 | -0.8988 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8475 | -0.5255 | -0.9770 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6167 | -0.7434 | -0.6728 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.28278 | 94.19 | -5.660 | -1.003 | -0.2035 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.867 | 0.6832 | 0.7537 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.487 | 1.227 | 1.370 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.28278</span> | 94.19 | 0.003481 | 0.2684 | 0.8159 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.179 | 1.867 | 0.6832 | 0.7537 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.487 | 1.227 | 1.370 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.442 | 0.7524 | -0.1734 | -0.03276 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06267 | -3.400 | 1.746 | -0.5960 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.307 | -1.411 | -1.323 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 69</span>| 480.27897 | 1.001 | -1.262 | -0.9141 | -0.8988 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8474 | -0.5252 | -0.9776 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6165 | -0.7431 | -0.6724 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.27897 | 94.13 | -5.662 | -1.003 | -0.2034 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.867 | 0.6827 | 0.7539 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.488 | 1.227 | 1.370 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.27897</span> | 94.13 | 0.003475 | 0.2684 | 0.8159 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.180 | 1.867 | 0.6827 | 0.7539 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.488 | 1.227 | 1.370 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.732 | 0.7463 | -0.1764 | -0.03625 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.08933 | -3.375 | 1.716 | 0.6486 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.273 | -1.374 | -1.283 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 70</span>| 480.27440 | 1.002 | -1.264 | -0.9140 | -0.8987 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8473 | -0.5250 | -0.9782 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6164 | -0.7427 | -0.6721 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.2744 | 94.19 | -5.664 | -1.003 | -0.2034 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.867 | 0.6823 | 0.7538 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.488 | 1.227 | 1.371 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.2744</span> | 94.19 | 0.003469 | 0.2684 | 0.8160 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.181 | 1.867 | 0.6823 | 0.7538 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.488 | 1.227 | 1.371 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.305 | 0.7431 | -0.1535 | -0.02884 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.05624 | -3.424 | 1.641 | -0.6166 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.366 | -1.368 | -1.291 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 71</span>| 480.27043 | 1.001 | -1.266 | -0.9140 | -0.8987 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8473 | -0.5247 | -0.9786 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6161 | -0.7423 | -0.6718 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.27043 | 94.13 | -5.666 | -1.002 | -0.2033 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.868 | 0.6819 | 0.7539 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.488 | 1.228 | 1.371 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.27043</span> | 94.13 | 0.003463 | 0.2685 | 0.8160 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.181 | 1.868 | 0.6819 | 0.7539 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.488 | 1.228 | 1.371 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.306 | 0.7372 | -0.1665 | -0.03186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.08221 | -3.333 | 1.631 | -0.6040 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.265 | -1.322 | -1.255 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 72</span>| 480.26665 | 1.002 | -1.267 | -0.9136 | -0.8986 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8471 | -0.5244 | -0.9791 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6160 | -0.7419 | -0.6714 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.26665 | 94.19 | -5.667 | -1.002 | -0.2032 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.868 | 0.6815 | 0.7540 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.488 | 1.228 | 1.371 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.26665</span> | 94.19 | 0.003457 | 0.2685 | 0.8161 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.182 | 1.868 | 0.6815 | 0.7540 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.488 | 1.228 | 1.371 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.654 | 0.7327 | -0.1326 | -0.02617 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.04981 | -3.394 | 1.559 | -0.6139 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.358 | -1.341 | -1.268 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 73</span>| 480.26300 | 1.001 | -1.269 | -0.9132 | -0.8985 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8470 | -0.5241 | -0.9796 | -1.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6158 | -0.7416 | -0.6711 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.263 | 94.13 | -5.669 | -1.002 | -0.2032 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.868 | 0.6812 | 0.7542 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.488 | 1.229 | 1.372 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.263</span> | 94.13 | 0.003451 | 0.2686 | 0.8162 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.183 | 1.868 | 0.6812 | 0.7542 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.488 | 1.229 | 1.372 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.009 | 0.7258 | -0.1343 | -0.03035 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07619 | -3.164 | 1.609 | -0.5397 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.251 | -1.282 | -1.219 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 74</span>| 480.25930 | 1.002 | -1.271 | -0.9130 | -0.8985 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8469 | -0.5239 | -0.9802 | -1.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6155 | -0.7412 | -0.6708 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.2593 | 94.19 | -5.671 | -1.002 | -0.2031 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.868 | 0.6807 | 0.7543 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.489 | 1.229 | 1.372 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.2593</span> | 94.19 | 0.003445 | 0.2686 | 0.8162 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.184 | 1.868 | 0.6807 | 0.7543 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.489 | 1.229 | 1.372 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.851 | 0.7223 | -0.1045 | -0.02290 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.04316 | -3.376 | 1.478 | 0.6193 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.343 | -1.302 | -1.232 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 75</span>| 480.25486 | 1.001 | -1.273 | -0.9131 | -0.8984 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8469 | -0.5237 | -0.9805 | -1.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6152 | -0.7408 | -0.6705 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.25486 | 94.14 | -5.673 | -1.002 | -0.2030 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.868 | 0.6805 | 0.7542 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.489 | 1.230 | 1.373 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.25486</span> | 94.14 | 0.003439 | 0.2686 | 0.8162 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.184 | 1.868 | 0.6805 | 0.7542 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.489 | 1.230 | 1.373 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.282 | 0.7167 | -0.1236 | -0.02586 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06793 | -3.294 | 1.470 | 0.6693 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.247 | -1.242 | -1.194 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 76</span>| 480.25000 | 1.002 | -1.274 | -0.9134 | -0.8984 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8469 | -0.5231 | -0.9806 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6147 | -0.7402 | -0.6701 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.25 | 94.20 | -5.674 | -1.002 | -0.2030 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.869 | 0.6804 | 0.7539 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.490 | 1.230 | 1.373 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.25</span> | 94.20 | 0.003434 | 0.2686 | 0.8163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.184 | 1.869 | 0.6804 | 0.7539 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.490 | 1.230 | 1.373 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.823 | 0.7134 | -0.1173 | -0.02040 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.04062 | -3.151 | 1.491 | -0.5685 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.243 | -1.237 | -1.210 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 77</span>| 480.24598 | 1.001 | -1.276 | -0.9134 | -0.8984 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8469 | -0.5229 | -0.9809 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6145 | -0.7399 | -0.6698 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.24598 | 94.13 | -5.676 | -1.002 | -0.2030 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.869 | 0.6802 | 0.7539 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.490 | 1.231 | 1.373 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.24598</span> | 94.13 | 0.003427 | 0.2686 | 0.8163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.184 | 1.869 | 0.6802 | 0.7539 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.490 | 1.231 | 1.373 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.294 | 0.7076 | -0.1362 | -0.02383 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06566 | -3.147 | 1.461 | 0.6663 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.244 | -1.185 | -1.155 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 78</span>| 480.24152 | 1.002 | -1.278 | -0.9134 | -0.8983 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8469 | -0.5225 | -0.9813 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6142 | -0.7395 | -0.6694 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.24152 | 94.19 | -5.678 | -1.002 | -0.2030 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.869 | 0.6799 | 0.7538 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.490 | 1.231 | 1.374 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.24152</span> | 94.19 | 0.003421 | 0.2686 | 0.8163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.184 | 1.869 | 0.6799 | 0.7538 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.490 | 1.231 | 1.374 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.573 | 0.7031 | -0.1214 | -0.01999 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.04022 | -3.129 | 1.425 | 0.6287 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.274 | -1.197 | -1.174 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 79</span>| 480.23703 | 1.001 | -1.280 | -0.9136 | -0.8983 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8469 | -0.5223 | -0.9815 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6136 | -0.7392 | -0.6691 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.23703 | 94.13 | -5.680 | -1.002 | -0.2030 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.869 | 0.6797 | 0.7536 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.491 | 1.231 | 1.374 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.23703</span> | 94.13 | 0.003415 | 0.2685 | 0.8163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.184 | 1.869 | 0.6797 | 0.7536 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.491 | 1.231 | 1.374 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.496 | 0.6977 | -0.1464 | -0.02500 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06997 | -3.031 | 1.316 | 0.6455 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.198 | -1.144 | -1.124 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 80</span>| 480.23246 | 1.002 | -1.281 | -0.9138 | -0.8983 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8469 | -0.5219 | -0.9816 | -1.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6131 | -0.7387 | -0.6687 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.23246 | 94.19 | -5.681 | -1.002 | -0.2030 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.870 | 0.6796 | 0.7533 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.492 | 1.232 | 1.375 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.23246</span> | 94.19 | 0.003409 | 0.2685 | 0.8163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.184 | 1.870 | 0.6796 | 0.7533 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.492 | 1.232 | 1.375 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.825 | 0.6940 | -0.1347 | -0.01919 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.03939 | -3.118 | 1.378 | 0.5922 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.219 | -1.136 | -1.127 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 81</span>| 480.22809 | 1.001 | -1.283 | -0.9138 | -0.8983 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8469 | -0.5217 | -0.9816 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6127 | -0.7384 | -0.6684 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.22809 | 94.14 | -5.683 | -1.002 | -0.2029 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.870 | 0.6796 | 0.7531 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.492 | 1.232 | 1.375 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.22809</span> | 94.14 | 0.003403 | 0.2685 | 0.8163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.184 | 1.870 | 0.6796 | 0.7531 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.492 | 1.232 | 1.375 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.001 | 0.6885 | -0.1518 | -0.02256 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06414 | -2.892 | 1.443 | 0.6415 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.085 | -1.098 | -1.101 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 82</span>| 480.22387 | 1.002 | -1.285 | -0.9139 | -0.8983 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8469 | -0.5212 | -0.9821 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6124 | -0.7381 | -0.6680 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.22387 | 94.19 | -5.685 | -1.002 | -0.2029 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.870 | 0.6793 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.492 | 1.232 | 1.375 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.22387</span> | 94.19 | 0.003397 | 0.2685 | 0.8163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.184 | 1.870 | 0.6793 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.492 | 1.232 | 1.375 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.360 | 0.6846 | -0.1392 | -0.01938 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.04006 | -2.853 | 1.421 | -0.5715 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.064 | -1.117 | -1.118 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 83</span>| 480.22054 | 1.001 | -1.287 | -0.9139 | -0.8983 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8469 | -0.5210 | -0.9826 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6125 | -0.7380 | -0.6676 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.22054 | 94.14 | -5.687 | -1.002 | -0.2029 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.871 | 0.6789 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.492 | 1.233 | 1.376 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.22054</span> | 94.14 | 0.003391 | 0.2685 | 0.8163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.184 | 1.871 | 0.6789 | 0.7530 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.492 | 1.233 | 1.376 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.774 | 0.6781 | -0.1521 | -0.02419 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06697 | -2.800 | 1.392 | 0.6467 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.111 | -1.074 | -1.064 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 84</span>| 480.21670 | 1.002 | -1.288 | -0.9138 | -0.8983 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8469 | -0.5206 | -0.9832 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6123 | -0.7378 | -0.6672 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.2167 | 94.19 | -5.688 | -1.002 | -0.2029 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.871 | 0.6784 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.493 | 1.233 | 1.376 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.2167</span> | 94.19 | 0.003385 | 0.2685 | 0.8163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.184 | 1.871 | 0.6784 | 0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.493 | 1.233 | 1.376 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.519 | 0.6730 | -0.1351 | -0.02088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.04118 | -2.856 | 1.311 | 0.6094 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.165 | -1.062 | -1.048 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 85</span>| 480.21269 | 1.001 | -1.290 | -0.9139 | -0.8983 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8469 | -0.5205 | -0.9835 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6119 | -0.7376 | -0.6670 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.21269 | 94.14 | -5.690 | -1.002 | -0.2029 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.871 | 0.6782 | 0.7527 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.493 | 1.233 | 1.377 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.21269</span> | 94.14 | 0.003379 | 0.2685 | 0.8163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.184 | 1.871 | 0.6782 | 0.7527 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.493 | 1.233 | 1.377 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.933 | 0.6686 | -0.1517 | -0.01805 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06304 | -2.806 | 1.298 | 0.6045 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.073 | -1.045 | -1.026 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 86</span>| 480.20865 | 1.002 | -1.292 | -0.9139 | -0.8983 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8469 | -0.5201 | -0.9839 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6115 | -0.7373 | -0.6667 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.20865 | 94.19 | -5.692 | -1.002 | -0.2029 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.871 | 0.6779 | 0.7525 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.494 | 1.233 | 1.377 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.20865</span> | 94.19 | 0.003373 | 0.2685 | 0.8163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.184 | 1.871 | 0.6779 | 0.7525 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.494 | 1.233 | 1.377 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.802 | 0.6647 | -0.1367 | -0.01906 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.03994 | -2.699 | 1.311 | -0.5807 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.078 | -1.030 | -1.030 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 87</span>| 480.20558 | 1.001 | -1.294 | -0.9137 | -0.8983 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8468 | -0.5199 | -0.9842 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6113 | -0.7372 | -0.6665 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.20558 | 94.14 | -5.694 | -1.002 | -0.2029 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.871 | 0.6776 | 0.7525 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.494 | 1.233 | 1.377 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.20558</span> | 94.14 | 0.003367 | 0.2685 | 0.8163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.185 | 1.871 | 0.6776 | 0.7525 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.494 | 1.233 | 1.377 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.911 | 0.6576 | -0.1438 | -0.02051 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06613 | -2.751 | 1.246 | -0.6218 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.053 | -1.017 | -1.010 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 88</span>| 480.20291 | 1.002 | -1.296 | -0.9132 | -0.8982 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8467 | -0.5195 | -0.9848 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6112 | -0.7370 | -0.6662 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.20291 | 94.19 | -5.696 | -1.002 | -0.2029 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 1.872 | 0.6772 | 0.7527 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.494 | 1.234 | 1.377 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.20291</span> | 94.19 | 0.003361 | 0.2686 | 0.8164 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.186 | 1.872 | 0.6772 | 0.7527 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.494 | 1.234 | 1.377 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.296 | 0.6533 | -0.1055 | -0.01383 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.03435 | -2.750 | 1.192 | -0.6155 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.121 | -1.037 | -1.054 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 89</span>| 480.20010 | 1.001 | -1.297 | -0.9127 | -0.8982 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8466 | -0.5193 | -0.9850 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6110 | -0.7368 | -0.6658 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.2001 | 94.14 | -5.697 | -1.001 | -0.2028 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.103 | 1.872 | 0.6771 | 0.7528 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.494 | 1.234 | 1.378 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.2001</span> | 94.14 | 0.003355 | 0.2687 | 0.8164 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.187 | 1.872 | 0.6771 | 0.7528 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.494 | 1.234 | 1.378 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.841 | 0.6461 | -0.09617 | -0.01892 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.05600 | -2.503 | 1.255 | 0.6797 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.9587 | -1.006 | -0.9794 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 90</span>| 480.19652 | 1.002 | -1.299 | -0.9127 | -0.8982 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8466 | -0.5191 | -0.9853 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6108 | -0.7364 | -0.6653 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.19652 | 94.19 | -5.699 | -1.001 | -0.2028 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.103 | 1.872 | 0.6768 | 0.7526 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.494 | 1.234 | 1.378 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.19652</span> | 94.19 | 0.003349 | 0.2687 | 0.8164 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.187 | 1.872 | 0.6768 | 0.7526 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.494 | 1.234 | 1.378 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 91</span>| 480.19461 | 1.002 | -1.301 | -0.9128 | -0.8982 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8466 | -0.5193 | -0.9855 | -1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6107 | -0.7361 | -0.6650 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.19461 | 94.18 | -5.701 | -1.001 | -0.2028 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.103 | 1.872 | 0.6767 | 0.7526 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.494 | 1.235 | 1.379 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.19461</span> | 94.18 | 0.003342 | 0.2687 | 0.8164 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.187 | 1.872 | 0.6767 | 0.7526 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.494 | 1.235 | 1.379 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 92</span>| 480.18441 | 1.002 | -1.313 | -0.9134 | -0.8983 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8466 | -0.5209 | -0.9862 | -1.003 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6104 | -0.7344 | -0.6628 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.18441 | 94.17 | -5.713 | -1.002 | -0.2029 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.103 | 1.871 | 0.6762 | 0.7522 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.495 | 1.237 | 1.381 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.18441</span> | 94.17 | 0.003303 | 0.2686 | 0.8164 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.187 | 1.871 | 0.6762 | 0.7522 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.495 | 1.237 | 1.381 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 93</span>| 480.15712 | 1.001 | -1.360 | -0.9157 | -0.8984 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8466 | -0.5271 | -0.9890 | -1.004 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6089 | -0.7277 | -0.6540 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.15712 | 94.12 | -5.760 | -1.004 | -0.2031 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.103 | 1.866 | 0.6740 | 0.7509 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.497 | 1.244 | 1.391 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.15712</span> | 94.12 | 0.003151 | 0.2681 | 0.8162 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.187 | 1.866 | 0.6740 | 0.7509 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.497 | 1.244 | 1.391 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 94</span>| 480.23418 | 0.9997 | -1.543 | -0.9246 | -0.8991 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8465 | -0.5509 | -1.000 | -1.011 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6032 | -0.7017 | -0.6198 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.23418 | 93.97 | -5.943 | -1.013 | -0.2037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.103 | 1.847 | 0.6655 | 0.7454 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.503 | 1.272 | 1.431 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.23418</span> | 93.97 | 0.002624 | 0.2664 | 0.8157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.187 | 1.847 | 0.6655 | 0.7454 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.503 | 1.272 | 1.431 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -6.048 | 0.4781 | -0.2230 | -0.02217 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.05480 | -3.577 | 0.9301 | 0.6494 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.028 | -0.4525 | -0.4232 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 95</span>| 480.10748 | 1.002 | -1.612 | -0.8919 | -0.8955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8419 | -0.5057 | -1.005 | -1.011 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6089 | -0.7402 | -0.6757 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.10748 | 94.20 | -6.012 | -0.9804 | -0.2001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.107 | 1.883 | 0.6618 | 0.7449 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.497 | 1.230 | 1.367 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.10748</span> | 94.20 | 0.002450 | 0.2728 | 0.8186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.225 | 1.883 | 0.6618 | 0.7449 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.497 | 1.230 | 1.367 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.588 | -0.2032 | 1.050 | 0.05863 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1556 | -1.013 | -0.1797 | 0.1430 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.088 | -1.192 | -1.504 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 96</span>| 480.44664 | 1.003 | -1.804 | -0.9880 | -0.8940 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8524 | -0.4601 | -0.9127 | -1.040 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5485 | -0.7099 | -0.6226 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.44664 | 94.31 | -6.204 | -1.077 | -0.1987 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.097 | 1.919 | 0.7320 | 0.7196 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.568 | 1.263 | 1.427 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.44664</span> | 94.31 | 0.002022 | 0.2542 | 0.8198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.139 | 1.919 | 0.7320 | 0.7196 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.568 | 1.263 | 1.427 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 97</span>| 480.05051 | 1.002 | -1.657 | -0.9147 | -0.8952 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8444 | -0.4949 | -0.9832 | -1.018 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5946 | -0.7329 | -0.6630 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.05051 | 94.19 | -6.057 | -1.003 | -0.1998 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.105 | 1.891 | 0.6784 | 0.7389 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.514 | 1.238 | 1.381 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.05051</span> | 94.19 | 0.002341 | 0.2683 | 0.8189 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.205 | 1.891 | 0.6784 | 0.7389 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.514 | 1.238 | 1.381 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.048 | -0.2764 | -0.02525 | 0.07726 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1002 | 0.1555 | 1.072 | 0.1458 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5013 | -0.7465 | -0.9442 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 98</span>| 480.05873 | 1.002 | -1.641 | -0.9145 | -0.9051 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8597 | -0.5017 | -0.9961 | -1.019 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5552 | -0.7600 | -0.6392 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.05873 | 94.21 | -6.041 | -1.003 | -0.2097 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.089 | 1.886 | 0.6686 | 0.7381 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.561 | 1.209 | 1.408 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.05873</span> | 94.21 | 0.002380 | 0.2684 | 0.8108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.080 | 1.886 | 0.6686 | 0.7381 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.561 | 1.209 | 1.408 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 99</span>| 480.03299 | 1.002 | -1.650 | -0.9146 | -0.8993 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8508 | -0.4977 | -0.9887 | -1.018 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5780 | -0.7442 | -0.6529 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.03299 | 94.17 | -6.050 | -1.003 | -0.2040 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.098 | 1.889 | 0.6742 | 0.7386 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.533 | 1.226 | 1.393 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.03299</span> | 94.17 | 0.002357 | 0.2683 | 0.8155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.152 | 1.889 | 0.6742 | 0.7386 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.533 | 1.226 | 1.393 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.07884 | -0.2508 | -0.03233 | -0.02314 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1302 | 0.06288 | 0.7629 | 0.2261 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.3850 | -1.277 | -0.6610 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 100</span>| 480.00970 | 1.003 | -1.641 | -0.9125 | -0.9005 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8500 | -0.4980 | -0.9983 | -1.021 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5841 | -0.7275 | -0.6414 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.0097 | 94.26 | -6.041 | -1.001 | -0.2051 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.889 | 0.6670 | 0.7367 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.526 | 1.244 | 1.406 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.0097</span> | 94.26 | 0.002380 | 0.2687 | 0.8145 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.159 | 1.889 | 0.6670 | 0.7367 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.526 | 1.244 | 1.406 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 12.51 | -0.2151 | 0.1066 | -0.04414 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06212 | -0.2557 | 0.09002 | -0.09728 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.06582 | -0.3883 | 0.07016 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 101</span>| 480.02569 | 1.000 | -1.627 | -0.9257 | -0.9015 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8496 | -0.4974 | -1.010 | -1.023 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5876 | -0.7200 | -0.6493 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.02569 | 94.03 | -6.027 | -1.014 | -0.2061 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.889 | 0.6581 | 0.7348 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.522 | 1.252 | 1.397 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.02569</span> | 94.03 | 0.002413 | 0.2662 | 0.8138 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.162 | 1.889 | 0.6581 | 0.7348 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.522 | 1.252 | 1.397 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 102</span>| 480.01783 | 1.000 | -1.636 | -0.9171 | -0.9008 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8499 | -0.4978 | -1.002 | -1.021 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5853 | -0.7249 | -0.6441 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.01783 | 94.03 | -6.036 | -1.006 | -0.2055 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.889 | 0.6639 | 0.7361 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.525 | 1.247 | 1.403 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.01783</span> | 94.03 | 0.002392 | 0.2678 | 0.8143 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.160 | 1.889 | 0.6639 | 0.7361 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.525 | 1.247 | 1.403 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 103</span>| 480.01762 | 1.000 | -1.639 | -0.9140 | -0.9006 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8500 | -0.4979 | -0.9995 | -1.021 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5844 | -0.7266 | -0.6422 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.01762 | 94.04 | -6.039 | -1.002 | -0.2052 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.889 | 0.6660 | 0.7365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.526 | 1.245 | 1.405 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.01762</span> | 94.04 | 0.002384 | 0.2685 | 0.8145 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.159 | 1.889 | 0.6660 | 0.7365 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.526 | 1.245 | 1.405 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 104</span>| 480.00603 | 1.001 | -1.641 | -0.9125 | -0.9005 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8500 | -0.4980 | -0.9983 | -1.021 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5841 | -0.7275 | -0.6414 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.00603 | 94.12 | -6.041 | -1.001 | -0.2051 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.889 | 0.6670 | 0.7367 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.526 | 1.244 | 1.406 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.00603</span> | 94.12 | 0.002380 | 0.2687 | 0.8145 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.159 | 1.889 | 0.6670 | 0.7367 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.526 | 1.244 | 1.406 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -6.885 | -0.2187 | 0.06031 | -0.05864 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1316 | -0.6942 | -0.07940 | 0.7419 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2628 | -0.6303 | -0.1748 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 105</span>| 480.00355 | 1.002 | -1.640 | -0.9125 | -0.9004 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8497 | -0.4981 | -0.9983 | -1.021 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5835 | -0.7267 | -0.6420 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.00355 | 94.17 | -6.040 | -1.001 | -0.2050 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.099 | 1.889 | 0.6669 | 0.7366 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.527 | 1.245 | 1.405 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.00355</span> | 94.17 | 0.002382 | 0.2687 | 0.8147 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.162 | 1.889 | 0.6669 | 0.7366 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.527 | 1.245 | 1.405 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.1332 | -0.2152 | 0.07761 | -0.04946 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09731 | -0.07704 | 0.1258 | 0.9492 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.08309 | -0.3432 | 0.03979 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 106</span>| 480.00003 | 1.002 | -1.640 | -0.9126 | -0.9003 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8495 | -0.4980 | -0.9985 | -1.022 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5836 | -0.7262 | -0.6420 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.00003 | 94.19 | -6.040 | -1.001 | -0.2049 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 1.889 | 0.6668 | 0.7355 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.527 | 1.245 | 1.405 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.00003</span> | 94.19 | 0.002382 | 0.2687 | 0.8147 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.163 | 1.889 | 0.6668 | 0.7355 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.527 | 1.245 | 1.405 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.294 | -0.2073 | 0.08146 | -0.04541 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07807 | -0.2293 | 0.05730 | 0.8075 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.008164 | -0.3171 | 0.03808 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 107</span>| 479.99578 | 1.002 | -1.638 | -0.9109 | -0.8997 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8483 | -0.4984 | -0.9975 | -1.023 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5809 | -0.7230 | -0.6440 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.99578 | 94.17 | -6.038 | -0.9994 | -0.2043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 1.889 | 0.6675 | 0.7343 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.530 | 1.249 | 1.403 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.99578</span> | 94.17 | 0.002387 | 0.2691 | 0.8152 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.172 | 1.889 | 0.6675 | 0.7343 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.530 | 1.249 | 1.403 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 108</span>| 479.99301 | 1.002 | -1.632 | -0.9055 | -0.8980 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8447 | -0.4999 | -0.9947 | -1.027 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5728 | -0.7134 | -0.6498 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.99301 | 94.16 | -6.032 | -0.9941 | -0.2026 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.104 | 1.887 | 0.6697 | 0.7310 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.540 | 1.259 | 1.396 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.99301</span> | 94.16 | 0.002402 | 0.2701 | 0.8166 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.202 | 1.887 | 0.6697 | 0.7310 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.540 | 1.259 | 1.396 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.5972 | -0.1625 | 0.4650 | 0.009686 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08636 | -1.694 | -0.1652 | -1.042 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1517 | 0.4204 | -0.3659 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 109</span>| 479.98697 | 1.002 | -1.611 | -0.9101 | -0.8945 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8385 | -0.4966 | -0.9980 | -1.027 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5750 | -0.7140 | -0.6459 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.98697 | 94.17 | -6.011 | -0.9986 | -0.1991 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.111 | 1.890 | 0.6672 | 0.7309 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.537 | 1.259 | 1.401 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.98697</span> | 94.17 | 0.002451 | 0.2692 | 0.8195 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.253 | 1.890 | 0.6672 | 0.7309 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.537 | 1.259 | 1.401 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.005684 | -0.1115 | 0.2082 | 0.08938 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3008 | 0.01411 | 0.1052 | -0.7061 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.4111 | 0.4010 | -0.1199 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 110</span>| 479.98697 | 1.002 | -1.611 | -0.9101 | -0.8945 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8385 | -0.4966 | -0.9980 | -1.027 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5750 | -0.7140 | -0.6459 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.98697 | 94.17 | -6.011 | -0.9986 | -0.1991 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.111 | 1.890 | 0.6672 | 0.7309 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.537 | 1.259 | 1.401 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.98697</span> | 94.17 | 0.002451 | 0.2692 | 0.8195 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.253 | 1.890 | 0.6672 | 0.7309 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.537 | 1.259 | 1.401 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>initial ETAs were nudged; (can control by foceiControl(etaNudge=., etaNudge2=))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>ETAs were reset to zero during optimization; (Can control by foceiControl(resetEtaP=.))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>gradient problems with initial estimate and covariance; see $scaleInfo</span> +<span class="r-in"><span class="va">f_nlmixr_dfop_sfo_focei_const</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_const</span><span class="op">[</span><span class="st">"DFOP-SFO"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"focei"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="font-weight: bold;">Key:</span> U: Unscaled Parameters; X: Back-transformed parameters; G: Gill difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> F: Forward difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> C: Central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> M: Mixed forward and central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> Unscaled parameters for Omegas=chol(solve(omega));</span> +<span class="r-out co"><span class="r-pr">#></span> Diagonals are transformed, as specified by foceiControl(diagXform=)</span> +<span class="r-out co"><span class="r-pr">#></span> |-----+---------------+-----------+-----------+-----------+-----------|</span> +<span class="r-out co"><span class="r-pr">#></span> | #| Objective Fun | parent_0 | log_k_A1 |f_parent_qlogis | log_k1 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| log_k2 | g_qlogis | sigma | o1 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| o2 | o3 | o4 | o5 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| o6 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 1</span>| 517.20934 | 1.000 | -1.000 | -0.9109 | -0.9296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9779 | -0.8885 | -0.8592 | -0.8766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8740 | -0.8675 | -0.8712 | -0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8680 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 517.20934 | 94.00 | -5.400 | -0.9700 | -1.900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.300 | 0.1400 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 517.20934</span> | 94.00 | 0.004517 | 0.2749 | 0.1496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01357 | 0.5349 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | G| Gill Diff. | 64.43 | 1.648 | -0.07882 | -0.2050 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4304 | 0.05992 | -56.51 | 17.73 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.983 | -11.00 | -3.771 | 3.593 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -10.58 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 2</span>| 2737.3115 | 0.2806 | -1.018 | -0.9100 | -0.9273 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9731 | -0.8892 | -0.2282 | -1.075 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9854 | -0.7447 | -0.8291 | -0.9136 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7499 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 2737.3115 | 26.38 | -5.418 | -0.9691 | -1.898 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.295 | 0.1399 | 2.105 | 0.5864 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7671 | 1.329 | 1.042 | 0.8535 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.298 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 2737.3115</span> | 26.38 | 0.004434 | 0.2751 | 0.1499 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01363 | 0.5349 | 2.105 | 0.5864 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7671 | 1.329 | 1.042 | 0.8535 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.298 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 3</span>| 569.57476 | 0.9281 | -1.002 | -0.9108 | -0.9293 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9774 | -0.8886 | -0.7961 | -0.8964 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8851 | -0.8553 | -0.8670 | -0.8775 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8562 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 569.57476 | 87.24 | -5.402 | -0.9699 | -1.900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.300 | 0.1400 | 1.650 | 0.7166 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8537 | 1.198 | 1.004 | 0.8856 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.175 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 569.57476</span> | 87.24 | 0.004508 | 0.2749 | 0.1496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01358 | 0.5349 | 1.650 | 0.7166 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8537 | 1.198 | 1.004 | 0.8856 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.175 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 4</span>| 531.41065 | 0.9928 | -1.000 | -0.9109 | -0.9296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9778 | -0.8885 | -0.8528 | -0.8786 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8751 | -0.8663 | -0.8708 | -0.8739 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8668 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 531.41065 | 93.32 | -5.400 | -0.9700 | -1.900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.300 | 0.1400 | 1.605 | 0.7297 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8624 | 1.185 | 1.000 | 0.8888 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.163 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 531.41065</span> | 93.32 | 0.004516 | 0.2749 | 0.1496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01357 | 0.5349 | 1.605 | 0.7297 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8624 | 1.185 | 1.000 | 0.8888 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.163 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 5</span>| 531.74000 | 0.9993 | -1.000 | -0.9109 | -0.9296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9779 | -0.8885 | -0.8585 | -0.8768 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8741 | -0.8674 | -0.8712 | -0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8679 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 531.74 | 93.93 | -5.400 | -0.9700 | -1.900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.300 | 0.1400 | 1.601 | 0.7310 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8632 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 531.74</span> | 93.93 | 0.004516 | 0.2749 | 0.1496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01357 | 0.5349 | 1.601 | 0.7310 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8632 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 6</span>| 531.81753 | 0.9999 | -1.000 | -0.9109 | -0.9296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9779 | -0.8885 | -0.8591 | -0.8767 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8740 | -0.8675 | -0.8712 | -0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8680 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 531.81753 | 93.99 | -5.400 | -0.9700 | -1.900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.300 | 0.1400 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 531.81753</span> | 93.99 | 0.004517 | 0.2749 | 0.1496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01357 | 0.5349 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 7</span>| 531.82573 | 1.000 | -1.000 | -0.9109 | -0.9296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9779 | -0.8885 | -0.8591 | -0.8766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8740 | -0.8675 | -0.8712 | -0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8680 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 531.82573 | 94.00 | -5.400 | -0.9700 | -1.900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.300 | 0.1400 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 531.82573</span> | 94.00 | 0.004517 | 0.2749 | 0.1496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01357 | 0.5349 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 8</span>| 531.82668 | 1.000 | -1.000 | -0.9109 | -0.9296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9779 | -0.8885 | -0.8592 | -0.8766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8740 | -0.8675 | -0.8712 | -0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8680 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 531.82668 | 94.00 | -5.400 | -0.9700 | -1.900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.300 | 0.1400 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 531.82668</span> | 94.00 | 0.004517 | 0.2749 | 0.1496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01357 | 0.5349 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 9</span>| 531.82678 | 1.000 | -1.000 | -0.9109 | -0.9296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9779 | -0.8885 | -0.8592 | -0.8766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8740 | -0.8675 | -0.8712 | -0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8680 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 531.82678 | 94.00 | -5.400 | -0.9700 | -1.900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.300 | 0.1400 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 531.82678</span> | 94.00 | 0.004517 | 0.2749 | 0.1496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01357 | 0.5349 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 10</span>| 531.82679 | 1.000 | -1.000 | -0.9109 | -0.9296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9779 | -0.8885 | -0.8592 | -0.8766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8740 | -0.8675 | -0.8712 | -0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8680 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 531.82679 | 94.00 | -5.400 | -0.9700 | -1.900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.300 | 0.1400 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 531.82679</span> | 94.00 | 0.004517 | 0.2749 | 0.1496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01357 | 0.5349 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 11</span>| 531.82679 | 1.000 | -1.000 | -0.9109 | -0.9296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9779 | -0.8885 | -0.8592 | -0.8766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8740 | -0.8675 | -0.8712 | -0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8680 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 531.82679 | 94.00 | -5.400 | -0.9700 | -1.900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.300 | 0.1400 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 531.82679</span> | 94.00 | 0.004517 | 0.2749 | 0.1496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01357 | 0.5349 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 12</span>| 531.82678 | 1.000 | -1.000 | -0.9109 | -0.9296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9779 | -0.8885 | -0.8592 | -0.8766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8740 | -0.8675 | -0.8712 | -0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8680 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 531.82678 | 94.00 | -5.400 | -0.9700 | -1.900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.300 | 0.1400 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 531.82678</span> | 94.00 | 0.004517 | 0.2749 | 0.1496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01357 | 0.5349 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 13</span>| 531.82679 | 1.000 | -1.000 | -0.9109 | -0.9296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9779 | -0.8885 | -0.8592 | -0.8766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8740 | -0.8675 | -0.8712 | -0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8680 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 531.82679 | 94.00 | -5.400 | -0.9700 | -1.900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.300 | 0.1400 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 531.82679</span> | 94.00 | 0.004517 | 0.2749 | 0.1496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01357 | 0.5349 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 14</span>| 531.82679 | 1.000 | -1.000 | -0.9109 | -0.9296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9779 | -0.8885 | -0.8592 | -0.8766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8740 | -0.8675 | -0.8712 | -0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8680 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 531.82679 | 94.00 | -5.400 | -0.9700 | -1.900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.300 | 0.1400 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 531.82679</span> | 94.00 | 0.004517 | 0.2749 | 0.1496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01357 | 0.5349 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 15</span>| 531.82679 | 1.000 | -1.000 | -0.9109 | -0.9296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9779 | -0.8885 | -0.8592 | -0.8766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8740 | -0.8675 | -0.8712 | -0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8680 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 531.82679 | 94.00 | -5.400 | -0.9700 | -1.900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.300 | 0.1400 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 531.82679</span> | 94.00 | 0.004517 | 0.2749 | 0.1496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01357 | 0.5349 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 16</span>| 531.82679 | 1.000 | -1.000 | -0.9109 | -0.9296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9779 | -0.8885 | -0.8592 | -0.8766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8740 | -0.8675 | -0.8712 | -0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8680 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 531.82679 | 94.00 | -5.400 | -0.9700 | -1.900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.300 | 0.1400 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 531.82679</span> | 94.00 | 0.004517 | 0.2749 | 0.1496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01357 | 0.5349 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 17</span>| 531.82679 | 1.000 | -1.000 | -0.9109 | -0.9296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9779 | -0.8885 | -0.8592 | -0.8766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8740 | -0.8675 | -0.8712 | -0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8680 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 531.82679 | 94.00 | -5.400 | -0.9700 | -1.900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.300 | 0.1400 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 531.82679</span> | 94.00 | 0.004517 | 0.2749 | 0.1496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01357 | 0.5349 | 1.600 | 0.7311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8633 | 1.183 | 1.000 | 0.8891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.161 |...........|...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>initial ETAs were nudged; (can control by foceiControl(etaNudge=., etaNudge2=))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>last objective function was not at minimum, possible problems in optimization</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>using R matrix to calculate covariance, can check sandwich or S matrix with $covRS and $covS</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>gradient problems with initial estimate and covariance; see $scaleInfo</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Variance by variable is supported by 'saem' and 'focei'</span></span> +<span class="r-in"><span class="va">f_nlmixr_fomc_sfo_saem_obs</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_obs</span><span class="op">[</span><span class="st">"FOMC-SFO"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"saem"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → generate SAEM model</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-out co"><span class="r-pr">#></span> 1: 93.4067 -5.7935 -0.0604 2.2993 -1.1624 2.9450 1.7342 0.6650 0.5890 0.4750 14.5215 9.1023</span> +<span class="r-out co"><span class="r-pr">#></span> 2: 93.8811 -5.7873 -0.0289 2.3640 -1.0762 2.7977 2.0710 0.6317 0.5595 0.4512 11.1033 4.6425</span> +<span class="r-out co"><span class="r-pr">#></span> 3: 94.0397 -5.9934 0.0119 2.4035 -1.0703 3.0693 2.4524 0.6124 0.5316 0.4287 10.0698 3.4243</span> +<span class="r-out co"><span class="r-pr">#></span> 4: 93.8834 -6.0401 0.0041 2.3944 -1.0097 2.9159 3.1645 0.6120 0.5050 0.4073 9.2013 3.2162</span> +<span class="r-out co"><span class="r-pr">#></span> 5: 94.0163 -5.8381 -0.0267 2.3580 -1.0239 2.7701 3.0063 0.5814 0.4797 0.3869 9.0330 3.0330</span> +<span class="r-out co"><span class="r-pr">#></span> 6: 93.9753 -5.8371 -0.0315 2.3598 -1.0052 2.6316 2.8559 0.5708 0.4558 0.3675 8.6051 2.6518</span> +<span class="r-out co"><span class="r-pr">#></span> 7: 93.6109 -5.8741 -0.0401 2.3570 -1.0025 2.5000 2.7131 0.5691 0.4330 0.3492 8.4407 2.4701</span> +<span class="r-out co"><span class="r-pr">#></span> 8: 93.2480 -6.0361 -0.0523 2.3504 -1.0028 2.3750 3.1584 0.5407 0.4113 0.3317 8.6121 2.2437</span> +<span class="r-out co"><span class="r-pr">#></span> 9: 93.2245 -6.0431 -0.0503 2.3552 -0.9828 2.2562 3.9790 0.5395 0.3908 0.3151 8.6609 2.1129</span> +<span class="r-out co"><span class="r-pr">#></span> 10: 93.3040 -6.1080 -0.0503 2.3613 -0.9784 2.1434 4.8606 0.5401 0.3712 0.2994 8.6497 2.0865</span> +<span class="r-out co"><span class="r-pr">#></span> 11: 93.4509 -5.9532 -0.0503 2.3444 -0.9823 3.0948 4.6176 0.5679 0.3527 0.2844 8.1651 2.0310</span> +<span class="r-out co"><span class="r-pr">#></span> 12: 93.5099 -6.1699 -0.0503 2.3408 -0.9746 3.2814 4.3867 0.5679 0.3350 0.2702 8.1716 1.9862</span> +<span class="r-out co"><span class="r-pr">#></span> 13: 93.8052 -6.1984 -0.0474 2.3233 -0.9922 3.1173 4.6967 0.5644 0.3183 0.2567 8.2982 2.0040</span> +<span class="r-out co"><span class="r-pr">#></span> 14: 93.6510 -6.0090 -0.0429 2.3601 -0.9885 2.9615 4.4618 0.5526 0.3024 0.2438 8.3254 2.0605</span> +<span class="r-out co"><span class="r-pr">#></span> 15: 93.8952 -6.3354 -0.0394 2.3580 -0.9792 2.8134 5.2117 0.5657 0.2872 0.2316 8.1329 2.0520</span> +<span class="r-out co"><span class="r-pr">#></span> 16: 93.4703 -6.0722 -0.0434 2.3386 -1.0026 2.6727 4.9512 0.5781 0.2729 0.2201 8.0866 2.0994</span> +<span class="r-out co"><span class="r-pr">#></span> 17: 93.4238 -6.2132 -0.0755 2.3120 -1.0119 2.5391 4.7036 0.5495 0.2592 0.2091 7.5958 2.2864</span> +<span class="r-out co"><span class="r-pr">#></span> 18: 93.5288 -6.2747 -0.0616 2.3223 -1.0105 2.4121 4.4684 0.5467 0.2463 0.1986 7.1910 1.9828</span> +<span class="r-out co"><span class="r-pr">#></span> 19: 93.2607 -6.3635 -0.0631 2.3206 -1.0045 3.6271 4.8142 0.5405 0.2340 0.1928 7.3672 1.8187</span> +<span class="r-out co"><span class="r-pr">#></span> 20: 93.3918 -6.3241 -0.0742 2.2941 -1.0140 3.4457 4.9242 0.5596 0.2223 0.1950 7.1427 1.8754</span> +<span class="r-out co"><span class="r-pr">#></span> 21: 93.6794 -6.1336 -0.0758 2.3000 -1.0048 3.2734 4.6780 0.5565 0.2111 0.1852 7.0989 1.9232</span> +<span class="r-out co"><span class="r-pr">#></span> 22: 94.0006 -6.1882 -0.0800 2.3099 -1.0252 3.1098 4.4441 0.5354 0.2006 0.1870 7.0038 1.9920</span> +<span class="r-out co"><span class="r-pr">#></span> 23: 93.6433 -6.2626 -0.0841 2.2791 -1.0183 4.8893 4.4476 0.5276 0.1906 0.1798 6.3698 1.8787</span> +<span class="r-out co"><span class="r-pr">#></span> 24: 93.9545 -6.3772 -0.0816 2.2887 -1.0019 4.6448 5.1698 0.5293 0.1810 0.1779 6.5903 1.9474</span> +<span class="r-out co"><span class="r-pr">#></span> 25: 94.2280 -6.3235 -0.0839 2.2600 -0.9932 5.2801 4.9113 0.5262 0.1720 0.1806 6.5267 1.9807</span> +<span class="r-out co"><span class="r-pr">#></span> 26: 94.2022 -6.2830 -0.0883 2.2643 -1.0012 5.9595 4.6658 0.5225 0.1634 0.1795 6.3678 1.9659</span> +<span class="r-out co"><span class="r-pr">#></span> 27: 94.4398 -6.1769 -0.0894 2.2564 -1.0177 9.0771 4.4325 0.5207 0.1552 0.1880 6.4522 1.8590</span> +<span class="r-out co"><span class="r-pr">#></span> 28: 94.2586 -6.1652 -0.0882 2.2574 -1.0226 8.6233 4.2108 0.5158 0.1475 0.1881 6.3701 1.7882</span> +<span class="r-out co"><span class="r-pr">#></span> 29: 94.3490 -6.1505 -0.0854 2.2615 -1.0081 9.6333 4.0003 0.5109 0.1423 0.1833 6.3601 1.8485</span> +<span class="r-out co"><span class="r-pr">#></span> 30: 94.6929 -6.0285 -0.0909 2.2610 -1.0082 9.1517 3.8003 0.5117 0.1401 0.2097 6.2461 1.8606</span> +<span class="r-out co"><span class="r-pr">#></span> 31: 94.2553 -6.0390 -0.0896 2.2625 -1.0078 8.6941 3.6103 0.5072 0.1378 0.2088 6.3337 1.8220</span> +<span class="r-out co"><span class="r-pr">#></span> 32: 94.3096 -5.7252 -0.0886 2.2677 -0.9967 9.0244 3.4298 0.5051 0.1325 0.2015 6.4601 1.8880</span> +<span class="r-out co"><span class="r-pr">#></span> 33: 94.8327 -5.8775 -0.0865 2.2684 -0.9976 8.6305 3.2583 0.4920 0.1333 0.1993 6.4804 1.8203</span> +<span class="r-out co"><span class="r-pr">#></span> 34: 94.3527 -5.9488 -0.0826 2.2879 -0.9989 8.1989 3.1538 0.4969 0.1388 0.1984 6.4201 1.7696</span> +<span class="r-out co"><span class="r-pr">#></span> 35: 94.4411 -6.1171 -0.0826 2.2913 -0.9964 8.4377 3.7937 0.4969 0.1387 0.1972 6.3878 1.7612</span> +<span class="r-out co"><span class="r-pr">#></span> 36: 94.2058 -6.1151 -0.0844 2.2920 -1.0069 8.0158 3.7963 0.4962 0.1395 0.1938 6.2469 1.6680</span> +<span class="r-out co"><span class="r-pr">#></span> 37: 93.7449 -6.1251 -0.0925 2.2736 -1.0019 7.6150 3.8477 0.5101 0.1325 0.1841 6.1375 1.7472</span> +<span class="r-out co"><span class="r-pr">#></span> 38: 93.6861 -6.0575 -0.0934 2.2803 -1.0097 7.2343 3.6553 0.5119 0.1259 0.1862 6.0729 1.7608</span> +<span class="r-out co"><span class="r-pr">#></span> 39: 93.9767 -6.0314 -0.0999 2.2548 -1.0231 6.8726 3.4725 0.5195 0.1234 0.1951 6.1947 1.8276</span> +<span class="r-out co"><span class="r-pr">#></span> 40: 94.0297 -6.1559 -0.0989 2.2440 -1.0374 6.5290 3.8559 0.5199 0.1279 0.1891 6.0195 1.8906</span> +<span class="r-out co"><span class="r-pr">#></span> 41: 94.2069 -6.3055 -0.0820 2.2710 -1.0275 6.2025 4.7866 0.5304 0.1215 0.1858 6.1777 1.8541</span> +<span class="r-out co"><span class="r-pr">#></span> 42: 94.2400 -6.3179 -0.0790 2.2783 -1.0379 5.8924 4.6915 0.5253 0.1154 0.1794 6.0530 1.8960</span> +<span class="r-out co"><span class="r-pr">#></span> 43: 93.9851 -6.4096 -0.0784 2.2832 -1.0341 5.5978 5.0608 0.5163 0.1097 0.1773 6.0057 1.8136</span> +<span class="r-out co"><span class="r-pr">#></span> 44: 94.1440 -6.2214 -0.0746 2.2969 -1.0262 5.3179 4.8077 0.5130 0.1079 0.1851 6.1182 1.8390</span> +<span class="r-out co"><span class="r-pr">#></span> 45: 93.8847 -6.3883 -0.0745 2.3059 -1.0132 6.8202 5.1378 0.5130 0.1174 0.1769 6.1000 1.8391</span> +<span class="r-out co"><span class="r-pr">#></span> 46: 93.7228 -6.3305 -0.0794 2.3033 -1.0107 6.4792 4.8809 0.5095 0.1196 0.1783 6.2794 1.7304</span> +<span class="r-out co"><span class="r-pr">#></span> 47: 93.7031 -6.4232 -0.0796 2.3006 -1.0028 6.1552 5.5756 0.5092 0.1243 0.1887 6.1716 1.7279</span> +<span class="r-out co"><span class="r-pr">#></span> 48: 93.5210 -6.2770 -0.0794 2.2948 -1.0122 5.8475 5.2968 0.5098 0.1247 0.1863 5.9847 1.7994</span> +<span class="r-out co"><span class="r-pr">#></span> 49: 93.3676 -6.4486 -0.0754 2.3079 -1.0061 5.5551 5.4356 0.5018 0.1198 0.1858 6.1108 1.7598</span> +<span class="r-out co"><span class="r-pr">#></span> 50: 93.8573 -6.3944 -0.0755 2.3057 -1.0038 5.2773 5.2487 0.5063 0.1193 0.1843 6.0935 1.7725</span> +<span class="r-out co"><span class="r-pr">#></span> 51: 93.7004 -6.2783 -0.0854 2.2836 -1.0074 5.0135 4.9863 0.4932 0.1269 0.1858 6.1630 1.8063</span> +<span class="r-out co"><span class="r-pr">#></span> 52: 93.4843 -6.3763 -0.0962 2.2731 -1.0073 4.7628 5.0969 0.4815 0.1345 0.1924 6.0823 1.8013</span> +<span class="r-out co"><span class="r-pr">#></span> 53: 93.6971 -6.5002 -0.0887 2.2774 -1.0111 4.5246 5.7428 0.4726 0.1346 0.1982 6.1744 1.7695</span> +<span class="r-out co"><span class="r-pr">#></span> 54: 93.6176 -6.4928 -0.0917 2.2648 -1.0220 4.2984 5.4557 0.4765 0.1419 0.2017 6.3732 1.8195</span> +<span class="r-out co"><span class="r-pr">#></span> 55: 93.7072 -6.5760 -0.0833 2.2865 -1.0282 4.0835 5.9775 0.4732 0.1434 0.1963 6.3653 1.7028</span> +<span class="r-out co"><span class="r-pr">#></span> 56: 94.1360 -6.6854 -0.0901 2.2941 -1.0244 3.8793 7.2562 0.4637 0.1393 0.1935 6.3001 1.7878</span> +<span class="r-out co"><span class="r-pr">#></span> 57: 93.4627 -6.6255 -0.1049 2.2502 -1.0233 3.6854 6.8934 0.4847 0.1323 0.1878 6.2357 1.8480</span> +<span class="r-out co"><span class="r-pr">#></span> 58: 93.8066 -6.6603 -0.1049 2.2362 -1.0280 3.5011 6.9334 0.4847 0.1397 0.1872 6.3582 1.7787</span> +<span class="r-out co"><span class="r-pr">#></span> 59: 93.8599 -6.7837 -0.1046 2.2450 -1.0274 3.3260 8.4672 0.4853 0.1332 0.1833 6.1248 1.8066</span> +<span class="r-out co"><span class="r-pr">#></span> 60: 93.6190 -6.5618 -0.1055 2.2381 -1.0244 3.1597 8.0438 0.4742 0.1390 0.1858 6.2589 1.7881</span> +<span class="r-out co"><span class="r-pr">#></span> 61: 93.7045 -6.6482 -0.1159 2.2413 -1.0272 3.2942 7.8485 0.4655 0.1406 0.1827 5.8425 1.7744</span> +<span class="r-out co"><span class="r-pr">#></span> 62: 93.5232 -6.5027 -0.1168 2.2418 -1.0187 3.3810 7.4560 0.4766 0.1414 0.1790 5.9349 1.7717</span> +<span class="r-out co"><span class="r-pr">#></span> 63: 93.4884 -6.4221 -0.1164 2.2505 -1.0062 3.2119 7.0832 0.4768 0.1422 0.1752 6.0193 1.7434</span> +<span class="r-out co"><span class="r-pr">#></span> 64: 93.2305 -6.4456 -0.1153 2.2573 -1.0062 4.1468 6.7291 0.4776 0.1395 0.1753 5.8355 1.7529</span> +<span class="r-out co"><span class="r-pr">#></span> 65: 93.3743 -6.3237 -0.1227 2.2484 -1.0102 3.9395 6.3926 0.4864 0.1374 0.1800 5.6731 1.7808</span> +<span class="r-out co"><span class="r-pr">#></span> 66: 93.7132 -6.3178 -0.1186 2.2389 -0.9894 4.0557 6.0730 0.4909 0.1426 0.1807 5.7099 1.7283</span> +<span class="r-out co"><span class="r-pr">#></span> 67: 93.7490 -6.3514 -0.1155 2.2445 -0.9946 3.8529 5.7693 0.4938 0.1379 0.1830 5.7366 1.7847</span> +<span class="r-out co"><span class="r-pr">#></span> 68: 93.7617 -6.1181 -0.1251 2.2487 -0.9841 3.7650 5.4809 0.4816 0.1549 0.1769 5.6569 1.7415</span> +<span class="r-out co"><span class="r-pr">#></span> 69: 93.4342 -6.3588 -0.1301 2.2350 -0.9813 4.5688 5.2068 0.4745 0.1624 0.1736 5.5771 1.7091</span> +<span class="r-out co"><span class="r-pr">#></span> 70: 93.5303 -6.3266 -0.1330 2.2384 -0.9753 4.3404 4.9465 0.4734 0.1563 0.1699 5.5332 1.7256</span> +<span class="r-out co"><span class="r-pr">#></span> 71: 93.4733 -6.2859 -0.1364 2.2170 -0.9781 4.1234 4.6992 0.4701 0.1604 0.1649 5.6661 1.7335</span> +<span class="r-out co"><span class="r-pr">#></span> 72: 93.3055 -6.2502 -0.1462 2.2156 -0.9724 3.9172 4.7693 0.4519 0.1607 0.1582 5.4776 1.7679</span> +<span class="r-out co"><span class="r-pr">#></span> 73: 93.3010 -6.6844 -0.1490 2.2262 -0.9777 3.7213 6.9975 0.4426 0.1848 0.1640 5.7066 1.7588</span> +<span class="r-out co"><span class="r-pr">#></span> 74: 93.1104 -6.6720 -0.1484 2.2079 -0.9982 3.5353 6.7811 0.4436 0.1807 0.1732 5.7700 1.7343</span> +<span class="r-out co"><span class="r-pr">#></span> 75: 93.4534 -6.9644 -0.1480 2.2078 -0.9930 3.3585 8.7027 0.4497 0.1717 0.1708 5.5371 1.7098</span> +<span class="r-out co"><span class="r-pr">#></span> 76: 93.5886 -6.3503 -0.1491 2.1958 -0.9884 3.7136 8.2676 0.4509 0.1731 0.1706 5.3943 1.7340</span> +<span class="r-out co"><span class="r-pr">#></span> 77: 93.4345 -6.4976 -0.1531 2.1831 -0.9928 4.5945 7.8542 0.4592 0.1741 0.1703 5.5564 1.7164</span> +<span class="r-out co"><span class="r-pr">#></span> 78: 93.6007 -6.4885 -0.1538 2.1850 -0.9919 4.3647 7.4615 0.4607 0.1803 0.1692 5.4698 1.7354</span> +<span class="r-out co"><span class="r-pr">#></span> 79: 93.2897 -7.0329 -0.1518 2.1935 -0.9863 4.6922 10.9870 0.4569 0.1790 0.1608 5.3799 1.7484</span> +<span class="r-out co"><span class="r-pr">#></span> 80: 93.4130 -6.6634 -0.1531 2.1865 -0.9839 5.4720 10.4377 0.4585 0.1852 0.1543 5.4298 1.7237</span> +<span class="r-out co"><span class="r-pr">#></span> 81: 93.5828 -6.7204 -0.1563 2.1914 -0.9882 5.1984 9.9158 0.4548 0.1973 0.1600 5.4425 1.7741</span> +<span class="r-out co"><span class="r-pr">#></span> 82: 93.4450 -6.7357 -0.1537 2.1964 -0.9958 4.9384 10.1331 0.4577 0.1874 0.1632 5.6874 1.7789</span> +<span class="r-out co"><span class="r-pr">#></span> 83: 93.6109 -6.9249 -0.1493 2.2061 -0.9945 4.6915 11.1537 0.4474 0.1781 0.1686 5.4249 1.7317</span> +<span class="r-out co"><span class="r-pr">#></span> 84: 93.7133 -6.8029 -0.1493 2.2016 -0.9886 4.4569 10.9568 0.4474 0.1715 0.1689 5.5426 1.7227</span> +<span class="r-out co"><span class="r-pr">#></span> 85: 93.8040 -6.6434 -0.1483 2.2032 -0.9861 5.4991 10.4090 0.4330 0.1749 0.1726 5.4570 1.7332</span> +<span class="r-out co"><span class="r-pr">#></span> 86: 93.9029 -6.7750 -0.1472 2.2066 -0.9892 5.2241 11.7325 0.4352 0.1819 0.1644 5.5652 1.6802</span> +<span class="r-out co"><span class="r-pr">#></span> 87: 93.8127 -6.7015 -0.1499 2.2019 -0.9891 4.9629 11.1459 0.4292 0.1977 0.1661 5.7122 1.6713</span> +<span class="r-out co"><span class="r-pr">#></span> 88: 93.6777 -6.7044 -0.1440 2.2074 -1.0050 4.7148 10.5886 0.4379 0.1878 0.1750 5.6084 1.7096</span> +<span class="r-out co"><span class="r-pr">#></span> 89: 94.0481 -6.2990 -0.1443 2.2085 -0.9869 4.4790 10.0591 0.4355 0.1951 0.1688 5.4280 1.8093</span> +<span class="r-out co"><span class="r-pr">#></span> 90: 93.6399 -6.3965 -0.1429 2.2138 -0.9737 5.1306 9.5562 0.4367 0.1917 0.1604 5.5652 1.7458</span> +<span class="r-out co"><span class="r-pr">#></span> 91: 93.8670 -6.3075 -0.1426 2.2128 -0.9856 5.1368 9.0784 0.4427 0.1993 0.1546 5.3927 1.8246</span> +<span class="r-out co"><span class="r-pr">#></span> 92: 93.7332 -6.4793 -0.1426 2.2091 -0.9835 5.0102 8.6245 0.4427 0.1986 0.1585 5.4463 1.7343</span> +<span class="r-out co"><span class="r-pr">#></span> 93: 93.8211 -6.3270 -0.1416 2.2123 -0.9941 4.7597 8.1932 0.4431 0.1908 0.1689 5.5213 1.7093</span> +<span class="r-out co"><span class="r-pr">#></span> 94: 93.7499 -6.0880 -0.1390 2.2158 -0.9960 5.1992 7.7836 0.4444 0.1958 0.1733 5.5329 1.7880</span> +<span class="r-out co"><span class="r-pr">#></span> 95: 93.6253 -6.2196 -0.1436 2.2126 -1.0053 4.9392 7.3944 0.4383 0.2011 0.1717 5.6042 1.7460</span> +<span class="r-out co"><span class="r-pr">#></span> 96: 93.8862 -6.1475 -0.1408 2.2211 -0.9922 4.6923 7.0247 0.4347 0.2077 0.1669 5.6807 1.6943</span> +<span class="r-out co"><span class="r-pr">#></span> 97: 93.7610 -6.2409 -0.1368 2.2281 -0.9864 4.4576 6.6734 0.4313 0.2084 0.1723 5.5387 1.7075</span> +<span class="r-out co"><span class="r-pr">#></span> 98: 93.5362 -6.3378 -0.1368 2.2294 -0.9813 4.2348 6.3398 0.4313 0.2127 0.1877 5.5850 1.6627</span> +<span class="r-out co"><span class="r-pr">#></span> 99: 93.5044 -6.2557 -0.1311 2.2282 -0.9993 4.0230 6.0228 0.4461 0.2167 0.1879 5.6437 1.7076</span> +<span class="r-out co"><span class="r-pr">#></span> 100: 93.3102 -6.3602 -0.1311 2.2368 -1.0040 3.8219 5.7216 0.4461 0.2139 0.1875 5.8029 1.7592</span> +<span class="r-out co"><span class="r-pr">#></span> 101: 93.4687 -6.0385 -0.1241 2.2347 -1.0031 3.6308 5.4356 0.4483 0.2035 0.1816 6.0097 1.7002</span> +<span class="r-out co"><span class="r-pr">#></span> 102: 93.6536 -6.2867 -0.1299 2.2421 -1.0002 3.4492 5.1743 0.4434 0.1993 0.1872 5.8540 1.7162</span> +<span class="r-out co"><span class="r-pr">#></span> 103: 93.9532 -6.2261 -0.1277 2.2361 -0.9931 3.2768 5.0546 0.4450 0.2069 0.1884 5.6688 1.7324</span> +<span class="r-out co"><span class="r-pr">#></span> 104: 93.9839 -6.1980 -0.1287 2.2286 -1.0081 3.1129 5.0671 0.4475 0.1997 0.1985 5.7690 1.7636</span> +<span class="r-out co"><span class="r-pr">#></span> 105: 94.1682 -6.1671 -0.1283 2.2217 -1.0154 2.9573 4.8137 0.4481 0.1976 0.1965 5.9277 1.7386</span> +<span class="r-out co"><span class="r-pr">#></span> 106: 94.2778 -6.1839 -0.1243 2.2323 -1.0022 3.5381 4.5730 0.4707 0.1980 0.1932 5.7059 1.7184</span> +<span class="r-out co"><span class="r-pr">#></span> 107: 94.3667 -5.9941 -0.1182 2.2283 -1.0191 3.3612 4.3444 0.4753 0.1984 0.1986 5.7813 1.7446</span> +<span class="r-out co"><span class="r-pr">#></span> 108: 94.2722 -6.1869 -0.1171 2.2293 -1.0027 3.6659 4.6329 0.4742 0.1986 0.2011 5.7827 1.7074</span> +<span class="r-out co"><span class="r-pr">#></span> 109: 94.1997 -6.2385 -0.1172 2.2241 -1.0083 3.4826 4.7954 0.4721 0.2027 0.2020 5.8339 1.7650</span> +<span class="r-out co"><span class="r-pr">#></span> 110: 94.3017 -6.3774 -0.1291 2.2229 -0.9857 3.7634 5.8516 0.4810 0.2126 0.1984 5.7961 1.6706</span> +<span class="r-out co"><span class="r-pr">#></span> 111: 93.9803 -6.0240 -0.1258 2.2273 -0.9879 3.5752 5.5590 0.4749 0.2060 0.1976 5.6243 1.7082</span> +<span class="r-out co"><span class="r-pr">#></span> 112: 94.1307 -6.0036 -0.1253 2.2365 -0.9886 4.0368 5.2810 0.4760 0.2060 0.1975 5.5732 1.7063</span> +<span class="r-out co"><span class="r-pr">#></span> 113: 93.8676 -6.2496 -0.1118 2.2600 -1.0080 3.8350 5.0170 0.4855 0.2109 0.2006 5.6406 1.7357</span> +<span class="r-out co"><span class="r-pr">#></span> 114: 93.5949 -6.3200 -0.1044 2.2449 -1.0172 3.6472 4.7661 0.4868 0.2095 0.2131 5.7690 1.7428</span> +<span class="r-out co"><span class="r-pr">#></span> 115: 93.6997 -6.3282 -0.1046 2.2567 -1.0135 3.4648 4.8622 0.4876 0.2264 0.2134 5.8853 1.7823</span> +<span class="r-out co"><span class="r-pr">#></span> 116: 93.8191 -6.0802 -0.1087 2.2535 -1.0011 3.4347 4.6191 0.4786 0.2176 0.2108 5.6553 1.7802</span> +<span class="r-out co"><span class="r-pr">#></span> 117: 93.8575 -6.0930 -0.1022 2.2498 -0.9898 3.3071 4.3881 0.4822 0.2163 0.2075 5.7806 1.8150</span> +<span class="r-out co"><span class="r-pr">#></span> 118: 93.9164 -5.9787 -0.1133 2.2535 -0.9861 4.2578 4.1687 0.4687 0.2198 0.2088 5.4441 1.8411</span> +<span class="r-out co"><span class="r-pr">#></span> 119: 93.8748 -6.0108 -0.1165 2.2488 -0.9775 4.0449 3.9603 0.4653 0.2271 0.2032 5.6119 1.7501</span> +<span class="r-out co"><span class="r-pr">#></span> 120: 93.6001 -6.0447 -0.1144 2.2477 -0.9821 3.8426 3.7623 0.4641 0.2223 0.2055 5.6454 1.7244</span> +<span class="r-out co"><span class="r-pr">#></span> 121: 93.6712 -5.9851 -0.1195 2.2484 -0.9917 3.6505 3.5742 0.4600 0.2143 0.2010 5.4083 1.7965</span> +<span class="r-out co"><span class="r-pr">#></span> 122: 93.6859 -6.0390 -0.1145 2.2497 -0.9888 3.4680 3.5595 0.4618 0.2136 0.1986 5.4111 1.7519</span> +<span class="r-out co"><span class="r-pr">#></span> 123: 93.6014 -5.8383 -0.1145 2.2584 -0.9893 3.6047 3.3815 0.4618 0.2155 0.2045 5.3624 1.7023</span> +<span class="r-out co"><span class="r-pr">#></span> 124: 93.6333 -5.7861 -0.1131 2.2556 -0.9872 3.4245 3.2125 0.4621 0.2153 0.2025 5.3930 1.7036</span> +<span class="r-out co"><span class="r-pr">#></span> 125: 93.4504 -5.9483 -0.1154 2.2531 -0.9924 3.2533 3.0518 0.4640 0.2175 0.2030 5.5097 1.6830</span> +<span class="r-out co"><span class="r-pr">#></span> 126: 93.5693 -5.8818 -0.1120 2.2506 -0.9960 3.0906 2.8992 0.4606 0.2267 0.2016 5.4583 1.6650</span> +<span class="r-out co"><span class="r-pr">#></span> 127: 93.7074 -5.8191 -0.1178 2.2412 -0.9891 2.9361 2.7543 0.4688 0.2234 0.2039 5.4861 1.8125</span> +<span class="r-out co"><span class="r-pr">#></span> 128: 93.5959 -5.8842 -0.1179 2.2544 -0.9985 3.0224 2.6166 0.4700 0.2237 0.2019 5.6417 1.8454</span> +<span class="r-out co"><span class="r-pr">#></span> 129: 93.5600 -5.8683 -0.1161 2.2365 -0.9987 3.4186 2.4857 0.4721 0.2182 0.1918 5.4391 1.8145</span> +<span class="r-out co"><span class="r-pr">#></span> 130: 93.4104 -5.8226 -0.1126 2.2355 -0.9892 3.3648 2.4231 0.4763 0.2212 0.1873 5.3999 1.7457</span> +<span class="r-out co"><span class="r-pr">#></span> 131: 93.5045 -5.7255 -0.1118 2.2486 -0.9918 4.1951 2.3020 0.4776 0.2121 0.1927 5.4342 1.7744</span> +<span class="r-out co"><span class="r-pr">#></span> 132: 93.2626 -5.8379 -0.1097 2.2510 -0.9933 3.9853 2.5572 0.4763 0.2114 0.1966 5.2979 1.7239</span> +<span class="r-out co"><span class="r-pr">#></span> 133: 93.4370 -5.9097 -0.1049 2.2578 -0.9939 4.2190 2.8246 0.4738 0.2036 0.2020 5.2853 1.6765</span> +<span class="r-out co"><span class="r-pr">#></span> 134: 93.8665 -5.9439 -0.1035 2.2654 -0.9832 4.0081 3.1228 0.4756 0.2102 0.1961 5.3467 1.7177</span> +<span class="r-out co"><span class="r-pr">#></span> 135: 93.6301 -5.8062 -0.1031 2.2702 -0.9737 3.9024 2.9667 0.4748 0.2101 0.2003 5.3053 1.6977</span> +<span class="r-out co"><span class="r-pr">#></span> 136: 93.7744 -5.9328 -0.1055 2.2685 -0.9764 3.7072 2.9952 0.4721 0.2096 0.1949 5.4319 1.6864</span> +<span class="r-out co"><span class="r-pr">#></span> 137: 93.6734 -5.9886 -0.1107 2.2517 -0.9732 3.8811 3.4962 0.4642 0.2204 0.1924 5.4294 1.6684</span> +<span class="r-out co"><span class="r-pr">#></span> 138: 93.7128 -5.9927 -0.1119 2.2517 -0.9775 3.6870 3.4543 0.4667 0.2204 0.1953 5.3912 1.7060</span> +<span class="r-out co"><span class="r-pr">#></span> 139: 93.6530 -6.1296 -0.1210 2.2456 -0.9929 3.5027 4.6472 0.4527 0.2296 0.1855 5.4953 1.7242</span> +<span class="r-out co"><span class="r-pr">#></span> 140: 93.9344 -6.2519 -0.1384 2.2304 -0.9970 3.6814 4.4707 0.4337 0.2182 0.1762 5.5643 1.7596</span> +<span class="r-out co"><span class="r-pr">#></span> 141: 93.7356 -6.2804 -0.1296 2.2549 -0.9921 3.9811 4.4876 0.4218 0.2361 0.1674 5.3531 1.7175</span> +<span class="r-out co"><span class="r-pr">#></span> 142: 93.7399 -6.0023 -0.1098 2.2611 -0.9815 3.7821 4.2632 0.4395 0.2421 0.1807 5.3139 1.7191</span> +<span class="r-out co"><span class="r-pr">#></span> 143: 93.4732 -6.0376 -0.1108 2.2689 -0.9734 3.5930 4.0500 0.4396 0.2541 0.1718 5.2930 1.6229</span> +<span class="r-out co"><span class="r-pr">#></span> 144: 93.4900 -5.9517 -0.1093 2.2876 -0.9675 3.4133 3.8475 0.4337 0.2542 0.1711 5.4258 1.5660</span> +<span class="r-out co"><span class="r-pr">#></span> 145: 93.4090 -5.9596 -0.1000 2.2942 -0.9756 3.2426 3.6551 0.4274 0.2422 0.1671 5.3539 1.6971</span> +<span class="r-out co"><span class="r-pr">#></span> 146: 93.4142 -5.9549 -0.0982 2.2846 -0.9704 3.0805 3.6092 0.4226 0.2339 0.1745 5.5092 1.6696</span> +<span class="r-out co"><span class="r-pr">#></span> 147: 93.4409 -6.0720 -0.0971 2.2942 -0.9891 2.9265 3.9922 0.4224 0.2373 0.1781 5.5599 1.6080</span> +<span class="r-out co"><span class="r-pr">#></span> 148: 93.4504 -6.2201 -0.0980 2.2855 -0.9832 2.7802 4.6985 0.4104 0.2464 0.1856 5.5016 1.5877</span> +<span class="r-out co"><span class="r-pr">#></span> 149: 93.4240 -6.2122 -0.1005 2.2728 -0.9881 3.7659 4.7755 0.4082 0.2642 0.1885 5.4942 1.5534</span> +<span class="r-out co"><span class="r-pr">#></span> 150: 93.5094 -6.1295 -0.1087 2.2717 -0.9941 3.5776 4.5367 0.4109 0.2611 0.1928 5.3468 1.5585</span> +<span class="r-out co"><span class="r-pr">#></span> 151: 93.4038 -6.2751 -0.1130 2.2643 -0.9892 3.3987 4.9866 0.4172 0.2638 0.1905 5.4955 1.6256</span> +<span class="r-out co"><span class="r-pr">#></span> 152: 93.5072 -6.3361 -0.1147 2.2627 -0.9988 2.3580 5.3824 0.4175 0.2656 0.1819 5.7685 1.6126</span> +<span class="r-out co"><span class="r-pr">#></span> 153: 93.3582 -6.2019 -0.1227 2.2526 -0.9929 2.5874 4.7052 0.4348 0.2621 0.1810 5.5149 1.6181</span> +<span class="r-out co"><span class="r-pr">#></span> 154: 93.1890 -6.3537 -0.1263 2.2446 -0.9871 2.4073 5.7070 0.4351 0.2586 0.1829 5.3136 1.6272</span> +<span class="r-out co"><span class="r-pr">#></span> 155: 93.1706 -6.4117 -0.1260 2.2484 -0.9845 2.3035 6.0004 0.4463 0.2586 0.1781 5.4260 1.6494</span> +<span class="r-out co"><span class="r-pr">#></span> 156: 93.3240 -6.3931 -0.1259 2.2469 -0.9824 2.5659 5.7375 0.4466 0.2781 0.1754 5.6202 1.6591</span> +<span class="r-out co"><span class="r-pr">#></span> 157: 93.3239 -6.1812 -0.1242 2.2541 -0.9743 1.6054 4.5906 0.4478 0.2657 0.1758 5.6806 1.6367</span> +<span class="r-out co"><span class="r-pr">#></span> 158: 93.3756 -6.2562 -0.1264 2.2706 -0.9888 1.5329 4.6790 0.4458 0.2532 0.1728 5.7756 1.6248</span> +<span class="r-out co"><span class="r-pr">#></span> 159: 93.3034 -6.3291 -0.1217 2.2524 -0.9954 1.7774 5.7204 0.4532 0.2642 0.1715 5.8189 1.6830</span> +<span class="r-out co"><span class="r-pr">#></span> 160: 93.4387 -6.5115 -0.1196 2.2488 -0.9846 2.2219 6.4960 0.4555 0.2728 0.1689 5.5273 1.6332</span> +<span class="r-out co"><span class="r-pr">#></span> 161: 93.7646 -6.3820 -0.1231 2.2520 -0.9837 2.8322 5.7269 0.4498 0.2712 0.1730 5.3659 1.5787</span> +<span class="r-out co"><span class="r-pr">#></span> 162: 93.6252 -6.4563 -0.1243 2.2472 -0.9867 2.8322 5.9119 0.4502 0.2671 0.1726 5.4519 1.5819</span> +<span class="r-out co"><span class="r-pr">#></span> 163: 93.6787 -6.6444 -0.1292 2.2366 -0.9899 2.0520 7.4835 0.4556 0.2705 0.1689 5.4095 1.5883</span> +<span class="r-out co"><span class="r-pr">#></span> 164: 93.7458 -6.9330 -0.1257 2.2430 -0.9872 1.7825 9.4340 0.4495 0.2701 0.1593 5.4517 1.6116</span> +<span class="r-out co"><span class="r-pr">#></span> 165: 93.7370 -6.9118 -0.1250 2.2421 -0.9832 1.9949 10.6549 0.4499 0.2685 0.1622 5.6272 1.6075</span> +<span class="r-out co"><span class="r-pr">#></span> 166: 94.0889 -6.8704 -0.1276 2.2409 -0.9872 1.5618 10.4435 0.4482 0.2608 0.1648 5.5891 1.6208</span> +<span class="r-out co"><span class="r-pr">#></span> 167: 94.1319 -7.2779 -0.1206 2.2505 -0.9894 1.5063 13.4312 0.4393 0.2549 0.1661 5.6013 1.6043</span> +<span class="r-out co"><span class="r-pr">#></span> 168: 93.8341 -6.9310 -0.1140 2.2495 -0.9844 1.7329 11.3224 0.4463 0.2540 0.1629 5.8366 1.6765</span> +<span class="r-out co"><span class="r-pr">#></span> 169: 93.8923 -6.6547 -0.1173 2.2620 -0.9872 1.4531 8.4608 0.4419 0.2414 0.1666 5.8784 1.6268</span> +<span class="r-out co"><span class="r-pr">#></span> 170: 94.0072 -6.3970 -0.1173 2.2606 -0.9861 1.4164 6.9237 0.4419 0.2468 0.1656 5.8793 1.6387</span> +<span class="r-out co"><span class="r-pr">#></span> 171: 93.8690 -6.5151 -0.1079 2.2482 -0.9880 1.9225 7.7681 0.4547 0.2404 0.1523 6.0158 1.6281</span> +<span class="r-out co"><span class="r-pr">#></span> 172: 93.6847 -6.3416 -0.1095 2.2438 -0.9849 2.0143 5.5739 0.4498 0.2450 0.1534 6.1355 1.6422</span> +<span class="r-out co"><span class="r-pr">#></span> 173: 93.4817 -6.3165 -0.1115 2.2573 -0.9885 1.6855 5.5626 0.4440 0.2471 0.1542 6.1343 1.6337</span> +<span class="r-out co"><span class="r-pr">#></span> 174: 93.6781 -6.2722 -0.1113 2.2521 -0.9958 1.9186 5.3383 0.4471 0.2427 0.1565 6.1081 1.6358</span> +<span class="r-out co"><span class="r-pr">#></span> 175: 93.7764 -6.1664 -0.1113 2.2468 -0.9864 1.6286 4.6233 0.4471 0.2426 0.1596 5.8892 1.6375</span> +<span class="r-out co"><span class="r-pr">#></span> 176: 93.9246 -6.2164 -0.1160 2.2529 -0.9853 1.0357 4.8013 0.4422 0.2471 0.1756 5.7340 1.6016</span> +<span class="r-out co"><span class="r-pr">#></span> 177: 93.9711 -6.1274 -0.1112 2.2540 -0.9883 1.2079 4.1536 0.4415 0.2492 0.1783 5.8399 1.6291</span> +<span class="r-out co"><span class="r-pr">#></span> 178: 93.9212 -6.0532 -0.1116 2.2593 -0.9742 1.2409 3.6443 0.4489 0.2458 0.1683 5.8422 1.6290</span> +<span class="r-out co"><span class="r-pr">#></span> 179: 94.0137 -6.0739 -0.1095 2.2664 -0.9778 1.5060 3.9878 0.4506 0.2370 0.1746 6.0349 1.6326</span> +<span class="r-out co"><span class="r-pr">#></span> 180: 93.9247 -6.0681 -0.1130 2.2660 -0.9934 1.9619 3.9582 0.4474 0.2328 0.1773 5.8082 1.6740</span> +<span class="r-out co"><span class="r-pr">#></span> 181: 93.7150 -6.0191 -0.1153 2.2558 -0.9915 2.6849 3.7075 0.4491 0.2283 0.1759 5.7187 1.6842</span> +<span class="r-out co"><span class="r-pr">#></span> 182: 93.5908 -6.1098 -0.1111 2.2769 -0.9942 3.0096 3.9325 0.4643 0.2275 0.1736 5.9243 1.6466</span> +<span class="r-out co"><span class="r-pr">#></span> 183: 93.3386 -6.0987 -0.1131 2.2630 -0.9962 3.5457 4.1285 0.4693 0.2373 0.1751 5.6948 1.7222</span> +<span class="r-out co"><span class="r-pr">#></span> 184: 93.4889 -6.3097 -0.1134 2.2660 -0.9720 3.0855 5.2642 0.4648 0.2255 0.1585 5.6827 1.7444</span> +<span class="r-out co"><span class="r-pr">#></span> 185: 93.6387 -6.1883 -0.1188 2.2622 -0.9603 3.3568 4.8291 0.4554 0.2223 0.1681 5.7089 1.8164</span> +<span class="r-out co"><span class="r-pr">#></span> 186: 93.3420 -6.2909 -0.1195 2.2656 -0.9835 3.2124 4.8317 0.4541 0.2286 0.1531 5.7574 1.7708</span> +<span class="r-out co"><span class="r-pr">#></span> 187: 93.4395 -6.0358 -0.1165 2.2528 -0.9917 3.8299 3.3301 0.4518 0.2370 0.1593 5.8508 1.6988</span> +<span class="r-out co"><span class="r-pr">#></span> 188: 93.5358 -6.0105 -0.1161 2.2540 -0.9813 5.1249 3.3448 0.4522 0.2361 0.1660 5.8700 1.6525</span> +<span class="r-out co"><span class="r-pr">#></span> 189: 93.4932 -6.1199 -0.1129 2.2636 -0.9812 4.5430 4.3213 0.4428 0.2359 0.1907 5.6970 1.7268</span> +<span class="r-out co"><span class="r-pr">#></span> 190: 93.4754 -5.9088 -0.1171 2.2564 -0.9614 4.6253 3.2590 0.4410 0.2399 0.1864 5.7116 1.8140</span> +<span class="r-out co"><span class="r-pr">#></span> 191: 93.4709 -5.9676 -0.1171 2.2568 -0.9748 4.8326 3.6704 0.4410 0.2428 0.1812 5.5925 1.7267</span> +<span class="r-out co"><span class="r-pr">#></span> 192: 93.3895 -5.9940 -0.1191 2.2523 -0.9691 4.3019 3.5174 0.4360 0.2484 0.1591 5.4631 1.7057</span> +<span class="r-out co"><span class="r-pr">#></span> 193: 93.4904 -6.0400 -0.1173 2.2519 -0.9697 4.6476 3.6255 0.4389 0.2388 0.1694 5.5362 1.7174</span> +<span class="r-out co"><span class="r-pr">#></span> 194: 93.4591 -5.9642 -0.1245 2.2626 -0.9559 5.3125 3.8133 0.4297 0.2550 0.1660 5.7591 1.7344</span> +<span class="r-out co"><span class="r-pr">#></span> 195: 93.6610 -6.2211 -0.1226 2.2580 -0.9669 5.2051 4.9271 0.4318 0.2414 0.1811 5.7010 1.7710</span> +<span class="r-out co"><span class="r-pr">#></span> 196: 93.4249 -5.9570 -0.1068 2.2735 -0.9727 5.1049 3.4872 0.4442 0.2429 0.1815 5.7753 1.7379</span> +<span class="r-out co"><span class="r-pr">#></span> 197: 93.4082 -6.0568 -0.1054 2.2754 -0.9865 5.2827 3.9305 0.4554 0.2408 0.1925 5.7514 1.7163</span> +<span class="r-out co"><span class="r-pr">#></span> 198: 93.3856 -5.8616 -0.1087 2.2708 -0.9686 4.1369 3.0197 0.4530 0.2473 0.1878 5.6920 1.7043</span> +<span class="r-out co"><span class="r-pr">#></span> 199: 93.5488 -6.0494 -0.1167 2.2682 -0.9719 3.8010 3.8897 0.4600 0.2445 0.1860 5.7126 1.6605</span> +<span class="r-out co"><span class="r-pr">#></span> 200: 93.3779 -5.9779 -0.1110 2.2761 -0.9780 3.5955 3.4721 0.4595 0.2468 0.1941 5.7539 1.6736</span> +<span class="r-out co"><span class="r-pr">#></span> 201: 93.4946 -6.0259 -0.1102 2.2676 -0.9755 3.0583 3.7305 0.4592 0.2554 0.1921 5.8877 1.6730</span> +<span class="r-out co"><span class="r-pr">#></span> 202: 93.4698 -6.0522 -0.1110 2.2685 -0.9703 2.9421 3.8718 0.4579 0.2595 0.1906 5.8527 1.6701</span> +<span class="r-out co"><span class="r-pr">#></span> 203: 93.4625 -6.0744 -0.1132 2.2642 -0.9696 3.1854 4.0983 0.4589 0.2596 0.1886 5.7532 1.6655</span> +<span class="r-out co"><span class="r-pr">#></span> 204: 93.4984 -6.0853 -0.1138 2.2589 -0.9718 3.2826 4.1667 0.4581 0.2588 0.1851 5.7274 1.6694</span> +<span class="r-out co"><span class="r-pr">#></span> 205: 93.5279 -6.1054 -0.1151 2.2562 -0.9742 3.3257 4.2680 0.4569 0.2584 0.1832 5.6976 1.6777</span> +<span class="r-out co"><span class="r-pr">#></span> 206: 93.6025 -6.1087 -0.1174 2.2518 -0.9767 3.2399 4.2443 0.4582 0.2589 0.1822 5.6809 1.6775</span> +<span class="r-out co"><span class="r-pr">#></span> 207: 93.6382 -6.0990 -0.1204 2.2481 -0.9801 3.2768 4.1473 0.4579 0.2591 0.1823 5.6460 1.6819</span> +<span class="r-out co"><span class="r-pr">#></span> 208: 93.6250 -6.0878 -0.1224 2.2438 -0.9812 3.1815 4.0872 0.4579 0.2577 0.1818 5.6256 1.6887</span> +<span class="r-out co"><span class="r-pr">#></span> 209: 93.6102 -6.0740 -0.1255 2.2394 -0.9803 3.1716 3.9968 0.4561 0.2573 0.1812 5.6063 1.6886</span> +<span class="r-out co"><span class="r-pr">#></span> 210: 93.6005 -6.0571 -0.1277 2.2348 -0.9799 3.2408 3.8923 0.4548 0.2572 0.1798 5.5849 1.6912</span> +<span class="r-out co"><span class="r-pr">#></span> 211: 93.6270 -6.0425 -0.1306 2.2292 -0.9807 3.3500 3.8267 0.4538 0.2586 0.1792 5.5578 1.6992</span> +<span class="r-out co"><span class="r-pr">#></span> 212: 93.6641 -6.0403 -0.1331 2.2253 -0.9806 3.4487 3.8366 0.4529 0.2596 0.1786 5.5422 1.7022</span> +<span class="r-out co"><span class="r-pr">#></span> 213: 93.6743 -6.0344 -0.1354 2.2214 -0.9800 3.5484 3.8260 0.4518 0.2606 0.1781 5.5250 1.7069</span> +<span class="r-out co"><span class="r-pr">#></span> 214: 93.6719 -6.0405 -0.1377 2.2179 -0.9804 3.5538 3.8785 0.4506 0.2612 0.1769 5.5148 1.7087</span> +<span class="r-out co"><span class="r-pr">#></span> 215: 93.6743 -6.0403 -0.1396 2.2146 -0.9801 3.5578 3.9180 0.4496 0.2615 0.1761 5.5118 1.7094</span> +<span class="r-out co"><span class="r-pr">#></span> 216: 93.6666 -6.0436 -0.1413 2.2115 -0.9796 3.5848 3.9484 0.4488 0.2624 0.1755 5.5015 1.7116</span> +<span class="r-out co"><span class="r-pr">#></span> 217: 93.6715 -6.0438 -0.1430 2.2086 -0.9794 3.6188 3.9603 0.4478 0.2631 0.1748 5.4884 1.7132</span> +<span class="r-out co"><span class="r-pr">#></span> 218: 93.6765 -6.0488 -0.1441 2.2060 -0.9796 3.6126 3.9885 0.4471 0.2632 0.1746 5.4714 1.7156</span> +<span class="r-out co"><span class="r-pr">#></span> 219: 93.6714 -6.0557 -0.1453 2.2038 -0.9798 3.6603 4.0118 0.4463 0.2632 0.1735 5.4593 1.7235</span> +<span class="r-out co"><span class="r-pr">#></span> 220: 93.6728 -6.0711 -0.1462 2.2027 -0.9794 3.7244 4.0910 0.4457 0.2639 0.1730 5.4531 1.7241</span> +<span class="r-out co"><span class="r-pr">#></span> 221: 93.6723 -6.0822 -0.1470 2.2015 -0.9788 3.7754 4.1554 0.4450 0.2647 0.1724 5.4511 1.7247</span> +<span class="r-out co"><span class="r-pr">#></span> 222: 93.6789 -6.0745 -0.1480 2.1998 -0.9780 3.8735 4.1186 0.4442 0.2662 0.1718 5.4419 1.7258</span> +<span class="r-out co"><span class="r-pr">#></span> 223: 93.6891 -6.0700 -0.1488 2.1984 -0.9778 3.9353 4.0998 0.4434 0.2681 0.1715 5.4375 1.7251</span> +<span class="r-out co"><span class="r-pr">#></span> 224: 93.7125 -6.0705 -0.1496 2.1976 -0.9774 4.0220 4.0861 0.4427 0.2697 0.1711 5.4378 1.7230</span> +<span class="r-out co"><span class="r-pr">#></span> 225: 93.7332 -6.0695 -0.1502 2.1966 -0.9775 4.0553 4.0669 0.4422 0.2712 0.1711 5.4355 1.7205</span> +<span class="r-out co"><span class="r-pr">#></span> 226: 93.7631 -6.0712 -0.1508 2.1951 -0.9779 4.0755 4.0572 0.4417 0.2728 0.1712 5.4347 1.7190</span> +<span class="r-out co"><span class="r-pr">#></span> 227: 93.7912 -6.0687 -0.1512 2.1938 -0.9785 4.0621 4.0439 0.4409 0.2742 0.1716 5.4325 1.7189</span> +<span class="r-out co"><span class="r-pr">#></span> 228: 93.8077 -6.0644 -0.1517 2.1927 -0.9791 4.0246 4.0190 0.4400 0.2755 0.1722 5.4269 1.7193</span> +<span class="r-out co"><span class="r-pr">#></span> 229: 93.8255 -6.0661 -0.1521 2.1909 -0.9796 3.9958 4.0166 0.4392 0.2769 0.1725 5.4214 1.7214</span> +<span class="r-out co"><span class="r-pr">#></span> 230: 93.8403 -6.0766 -0.1530 2.1895 -0.9802 4.0152 4.0548 0.4380 0.2788 0.1730 5.4214 1.7232</span> +<span class="r-out co"><span class="r-pr">#></span> 231: 93.8549 -6.0768 -0.1541 2.1877 -0.9810 4.0690 4.0542 0.4368 0.2803 0.1734 5.4157 1.7236</span> +<span class="r-out co"><span class="r-pr">#></span> 232: 93.8666 -6.0728 -0.1550 2.1858 -0.9816 4.0852 4.0337 0.4356 0.2818 0.1736 5.4136 1.7224</span> +<span class="r-out co"><span class="r-pr">#></span> 233: 93.8728 -6.0672 -0.1557 2.1844 -0.9820 4.1001 4.0000 0.4346 0.2828 0.1738 5.4028 1.7243</span> +<span class="r-out co"><span class="r-pr">#></span> 234: 93.8862 -6.0646 -0.1563 2.1830 -0.9825 4.1303 3.9850 0.4337 0.2838 0.1737 5.3924 1.7222</span> +<span class="r-out co"><span class="r-pr">#></span> 235: 93.8862 -6.0632 -0.1570 2.1819 -0.9827 4.1149 3.9735 0.4329 0.2847 0.1737 5.3846 1.7225</span> +<span class="r-out co"><span class="r-pr">#></span> 236: 93.8827 -6.0639 -0.1577 2.1814 -0.9834 4.1004 3.9711 0.4322 0.2852 0.1739 5.3838 1.7220</span> +<span class="r-out co"><span class="r-pr">#></span> 237: 93.8729 -6.0680 -0.1582 2.1808 -0.9840 4.0606 3.9866 0.4316 0.2857 0.1741 5.3806 1.7213</span> +<span class="r-out co"><span class="r-pr">#></span> 238: 93.8739 -6.0733 -0.1587 2.1806 -0.9845 4.0331 4.0011 0.4311 0.2859 0.1742 5.3775 1.7199</span> +<span class="r-out co"><span class="r-pr">#></span> 239: 93.8732 -6.0729 -0.1591 2.1802 -0.9853 3.9850 3.9892 0.4307 0.2859 0.1744 5.3782 1.7216</span> +<span class="r-out co"><span class="r-pr">#></span> 240: 93.8760 -6.0754 -0.1595 2.1796 -0.9854 3.9349 3.9867 0.4303 0.2858 0.1747 5.3781 1.7232</span> +<span class="r-out co"><span class="r-pr">#></span> 241: 93.8779 -6.0749 -0.1599 2.1791 -0.9853 3.9241 3.9801 0.4299 0.2858 0.1748 5.3757 1.7228</span> +<span class="r-out co"><span class="r-pr">#></span> 242: 93.8842 -6.0716 -0.1602 2.1786 -0.9852 3.9394 3.9651 0.4297 0.2859 0.1749 5.3726 1.7224</span> +<span class="r-out co"><span class="r-pr">#></span> 243: 93.8884 -6.0719 -0.1606 2.1778 -0.9851 3.9310 3.9741 0.4295 0.2857 0.1750 5.3705 1.7224</span> +<span class="r-out co"><span class="r-pr">#></span> 244: 93.8910 -6.0712 -0.1610 2.1771 -0.9850 3.9173 3.9819 0.4294 0.2856 0.1749 5.3700 1.7222</span> +<span class="r-out co"><span class="r-pr">#></span> 245: 93.9054 -6.0736 -0.1614 2.1764 -0.9854 3.9106 3.9984 0.4293 0.2856 0.1748 5.3711 1.7217</span> +<span class="r-out co"><span class="r-pr">#></span> 246: 93.9209 -6.0753 -0.1617 2.1757 -0.9859 3.9080 4.0071 0.4291 0.2852 0.1746 5.3711 1.7215</span> +<span class="r-out co"><span class="r-pr">#></span> 247: 93.9273 -6.0846 -0.1621 2.1752 -0.9861 3.8790 4.0580 0.4286 0.2851 0.1745 5.3755 1.7206</span> +<span class="r-out co"><span class="r-pr">#></span> 248: 93.9265 -6.0884 -0.1625 2.1749 -0.9865 3.8613 4.0784 0.4286 0.2848 0.1744 5.3760 1.7198</span> +<span class="r-out co"><span class="r-pr">#></span> 249: 93.9286 -6.0926 -0.1627 2.1746 -0.9872 3.8663 4.1008 0.4287 0.2845 0.1745 5.3755 1.7195</span> +<span class="r-out co"><span class="r-pr">#></span> 250: 93.9287 -6.0968 -0.1629 2.1744 -0.9878 3.8822 4.1269 0.4289 0.2844 0.1743 5.3755 1.7201</span> +<span class="r-out co"><span class="r-pr">#></span> 251: 93.9314 -6.1017 -0.1630 2.1739 -0.9882 3.8878 4.1495 0.4291 0.2843 0.1744 5.3729 1.7200</span> +<span class="r-out co"><span class="r-pr">#></span> 252: 93.9351 -6.1036 -0.1632 2.1734 -0.9885 3.8908 4.1545 0.4293 0.2843 0.1746 5.3684 1.7191</span> +<span class="r-out co"><span class="r-pr">#></span> 253: 93.9415 -6.1053 -0.1634 2.1729 -0.9889 3.8727 4.1602 0.4294 0.2842 0.1747 5.3650 1.7196</span> +<span class="r-out co"><span class="r-pr">#></span> 254: 93.9473 -6.1088 -0.1636 2.1723 -0.9891 3.8657 4.1769 0.4296 0.2843 0.1749 5.3666 1.7190</span> +<span class="r-out co"><span class="r-pr">#></span> 255: 93.9505 -6.1087 -0.1639 2.1717 -0.9888 3.8457 4.1720 0.4298 0.2841 0.1749 5.3617 1.7191</span> +<span class="r-out co"><span class="r-pr">#></span> 256: 93.9497 -6.1054 -0.1642 2.1715 -0.9885 3.8395 4.1559 0.4299 0.2839 0.1749 5.3598 1.7192</span> +<span class="r-out co"><span class="r-pr">#></span> 257: 93.9477 -6.1008 -0.1643 2.1713 -0.9882 3.8383 4.1360 0.4299 0.2836 0.1749 5.3567 1.7196</span> +<span class="r-out co"><span class="r-pr">#></span> 258: 93.9402 -6.0998 -0.1645 2.1713 -0.9880 3.8516 4.1288 0.4300 0.2832 0.1749 5.3565 1.7190</span> +<span class="r-out co"><span class="r-pr">#></span> 259: 93.9318 -6.0979 -0.1646 2.1711 -0.9879 3.8396 4.1182 0.4301 0.2829 0.1750 5.3583 1.7188</span> +<span class="r-out co"><span class="r-pr">#></span> 260: 93.9277 -6.1002 -0.1646 2.1713 -0.9879 3.8173 4.1273 0.4304 0.2826 0.1751 5.3611 1.7186</span> +<span class="r-out co"><span class="r-pr">#></span> 261: 93.9251 -6.0973 -0.1646 2.1714 -0.9879 3.8140 4.1105 0.4306 0.2822 0.1750 5.3588 1.7192</span> +<span class="r-out co"><span class="r-pr">#></span> 262: 93.9186 -6.1009 -0.1647 2.1715 -0.9880 3.8177 4.1303 0.4308 0.2822 0.1750 5.3604 1.7194</span> +<span class="r-out co"><span class="r-pr">#></span> 263: 93.9130 -6.1033 -0.1646 2.1715 -0.9880 3.8029 4.1529 0.4309 0.2822 0.1748 5.3647 1.7188</span> +<span class="r-out co"><span class="r-pr">#></span> 264: 93.9040 -6.1077 -0.1645 2.1717 -0.9879 3.7950 4.1820 0.4310 0.2822 0.1747 5.3699 1.7184</span> +<span class="r-out co"><span class="r-pr">#></span> 265: 93.9012 -6.1071 -0.1645 2.1714 -0.9879 3.7834 4.1895 0.4310 0.2822 0.1746 5.3755 1.7191</span> +<span class="r-out co"><span class="r-pr">#></span> 266: 93.8988 -6.1051 -0.1644 2.1714 -0.9879 3.7788 4.1822 0.4311 0.2822 0.1745 5.3765 1.7203</span> +<span class="r-out co"><span class="r-pr">#></span> 267: 93.8964 -6.1059 -0.1643 2.1714 -0.9877 3.7774 4.1896 0.4311 0.2822 0.1744 5.3792 1.7197</span> +<span class="r-out co"><span class="r-pr">#></span> 268: 93.8901 -6.1092 -0.1643 2.1715 -0.9876 3.7790 4.2198 0.4310 0.2822 0.1742 5.3811 1.7200</span> +<span class="r-out co"><span class="r-pr">#></span> 269: 93.8842 -6.1105 -0.1643 2.1717 -0.9875 3.7620 4.2336 0.4310 0.2823 0.1742 5.3838 1.7193</span> +<span class="r-out co"><span class="r-pr">#></span> 270: 93.8760 -6.1125 -0.1643 2.1721 -0.9874 3.7668 4.2483 0.4308 0.2823 0.1741 5.3852 1.7181</span> +<span class="r-out co"><span class="r-pr">#></span> 271: 93.8705 -6.1149 -0.1643 2.1722 -0.9873 3.7785 4.2625 0.4306 0.2823 0.1742 5.3853 1.7172</span> +<span class="r-out co"><span class="r-pr">#></span> 272: 93.8674 -6.1149 -0.1643 2.1723 -0.9871 3.7829 4.2581 0.4304 0.2823 0.1743 5.3836 1.7162</span> +<span class="r-out co"><span class="r-pr">#></span> 273: 93.8644 -6.1159 -0.1642 2.1725 -0.9870 3.7910 4.2631 0.4303 0.2825 0.1743 5.3818 1.7154</span> +<span class="r-out co"><span class="r-pr">#></span> 274: 93.8585 -6.1158 -0.1640 2.1728 -0.9869 3.7926 4.2612 0.4302 0.2825 0.1743 5.3816 1.7147</span> +<span class="r-out co"><span class="r-pr">#></span> 275: 93.8564 -6.1151 -0.1639 2.1732 -0.9867 3.8053 4.2581 0.4301 0.2826 0.1743 5.3804 1.7143</span> +<span class="r-out co"><span class="r-pr">#></span> 276: 93.8564 -6.1132 -0.1638 2.1736 -0.9866 3.7958 4.2486 0.4300 0.2827 0.1745 5.3810 1.7144</span> +<span class="r-out co"><span class="r-pr">#></span> 277: 93.8564 -6.1120 -0.1637 2.1741 -0.9867 3.7952 4.2426 0.4298 0.2829 0.1747 5.3808 1.7148</span> +<span class="r-out co"><span class="r-pr">#></span> 278: 93.8528 -6.1113 -0.1636 2.1743 -0.9867 3.7922 4.2352 0.4297 0.2832 0.1750 5.3819 1.7144</span> +<span class="r-out co"><span class="r-pr">#></span> 279: 93.8503 -6.1124 -0.1636 2.1744 -0.9867 3.7930 4.2390 0.4298 0.2834 0.1753 5.3826 1.7144</span> +<span class="r-out co"><span class="r-pr">#></span> 280: 93.8466 -6.1146 -0.1636 2.1743 -0.9867 3.7946 4.2470 0.4299 0.2838 0.1755 5.3832 1.7142</span> +<span class="r-out co"><span class="r-pr">#></span> 281: 93.8435 -6.1165 -0.1638 2.1743 -0.9867 3.7994 4.2552 0.4298 0.2840 0.1756 5.3828 1.7140</span> +<span class="r-out co"><span class="r-pr">#></span> 282: 93.8421 -6.1162 -0.1639 2.1741 -0.9868 3.7967 4.2496 0.4296 0.2843 0.1758 5.3816 1.7137</span> +<span class="r-out co"><span class="r-pr">#></span> 283: 93.8382 -6.1146 -0.1641 2.1740 -0.9866 3.7957 4.2387 0.4294 0.2845 0.1760 5.3796 1.7135</span> +<span class="r-out co"><span class="r-pr">#></span> 284: 93.8356 -6.1131 -0.1641 2.1740 -0.9865 3.7904 4.2263 0.4292 0.2848 0.1762 5.3776 1.7127</span> +<span class="r-out co"><span class="r-pr">#></span> 285: 93.8349 -6.1113 -0.1642 2.1740 -0.9865 3.7841 4.2129 0.4291 0.2850 0.1765 5.3763 1.7130</span> +<span class="r-out co"><span class="r-pr">#></span> 286: 93.8372 -6.1095 -0.1643 2.1741 -0.9864 3.7801 4.2035 0.4289 0.2853 0.1769 5.3779 1.7130</span> +<span class="r-out co"><span class="r-pr">#></span> 287: 93.8393 -6.1077 -0.1643 2.1741 -0.9864 3.7804 4.1908 0.4287 0.2857 0.1771 5.3785 1.7132</span> +<span class="r-out co"><span class="r-pr">#></span> 288: 93.8395 -6.1071 -0.1644 2.1740 -0.9866 3.7714 4.1834 0.4284 0.2859 0.1772 5.3798 1.7120</span> +<span class="r-out co"><span class="r-pr">#></span> 289: 93.8398 -6.1065 -0.1645 2.1738 -0.9865 3.7635 4.1765 0.4282 0.2861 0.1774 5.3821 1.7111</span> +<span class="r-out co"><span class="r-pr">#></span> 290: 93.8376 -6.1089 -0.1647 2.1737 -0.9865 3.7495 4.1853 0.4281 0.2863 0.1776 5.3852 1.7106</span> +<span class="r-out co"><span class="r-pr">#></span> 291: 93.8341 -6.1091 -0.1647 2.1738 -0.9863 3.7340 4.1854 0.4278 0.2865 0.1776 5.3868 1.7098</span> +<span class="r-out co"><span class="r-pr">#></span> 292: 93.8329 -6.1080 -0.1647 2.1741 -0.9863 3.7189 4.1760 0.4275 0.2868 0.1777 5.3885 1.7091</span> +<span class="r-out co"><span class="r-pr">#></span> 293: 93.8312 -6.1065 -0.1647 2.1743 -0.9862 3.7091 4.1651 0.4272 0.2871 0.1778 5.3896 1.7086</span> +<span class="r-out co"><span class="r-pr">#></span> 294: 93.8310 -6.1042 -0.1647 2.1745 -0.9861 3.6946 4.1521 0.4269 0.2874 0.1780 5.3908 1.7077</span> +<span class="r-out co"><span class="r-pr">#></span> 295: 93.8299 -6.1033 -0.1648 2.1747 -0.9861 3.6968 4.1433 0.4265 0.2880 0.1781 5.3904 1.7066</span> +<span class="r-out co"><span class="r-pr">#></span> 296: 93.8276 -6.1027 -0.1648 2.1749 -0.9862 3.7072 4.1361 0.4261 0.2885 0.1782 5.3910 1.7056</span> +<span class="r-out co"><span class="r-pr">#></span> 297: 93.8212 -6.1015 -0.1647 2.1750 -0.9859 3.7253 4.1278 0.4256 0.2891 0.1783 5.3927 1.7051</span> +<span class="r-out co"><span class="r-pr">#></span> 298: 93.8173 -6.0980 -0.1647 2.1751 -0.9858 3.7552 4.1115 0.4251 0.2897 0.1784 5.3932 1.7045</span> +<span class="r-out co"><span class="r-pr">#></span> 299: 93.8168 -6.0984 -0.1646 2.1754 -0.9856 3.7687 4.1143 0.4246 0.2902 0.1786 5.3949 1.7037</span> +<span class="r-out co"><span class="r-pr">#></span> 300: 93.8154 -6.0967 -0.1646 2.1756 -0.9855 3.7888 4.1072 0.4241 0.2906 0.1788 5.3962 1.7030</span> +<span class="r-out co"><span class="r-pr">#></span> 301: 93.8129 -6.0946 -0.1646 2.1757 -0.9852 3.8097 4.1006 0.4236 0.2911 0.1791 5.3971 1.7026</span> +<span class="r-out co"><span class="r-pr">#></span> 302: 93.8120 -6.0932 -0.1646 2.1759 -0.9849 3.8403 4.0955 0.4231 0.2917 0.1792 5.3971 1.7021</span> +<span class="r-out co"><span class="r-pr">#></span> 303: 93.8115 -6.0942 -0.1646 2.1762 -0.9850 3.8602 4.1004 0.4227 0.2922 0.1795 5.3976 1.7020</span> +<span class="r-out co"><span class="r-pr">#></span> 304: 93.8106 -6.0979 -0.1645 2.1765 -0.9850 3.8898 4.1217 0.4222 0.2926 0.1798 5.3975 1.7024</span> +<span class="r-out co"><span class="r-pr">#></span> 305: 93.8091 -6.1009 -0.1644 2.1767 -0.9851 3.9165 4.1374 0.4218 0.2931 0.1801 5.3989 1.7024</span> +<span class="r-out co"><span class="r-pr">#></span> 306: 93.8090 -6.1043 -0.1644 2.1770 -0.9850 3.9485 4.1617 0.4214 0.2936 0.1803 5.3998 1.7021</span> +<span class="r-out co"><span class="r-pr">#></span> 307: 93.8082 -6.1063 -0.1644 2.1772 -0.9850 3.9730 4.1797 0.4210 0.2940 0.1803 5.3998 1.7017</span> +<span class="r-out co"><span class="r-pr">#></span> 308: 93.8093 -6.1090 -0.1644 2.1775 -0.9850 3.9874 4.2026 0.4205 0.2945 0.1804 5.3996 1.7006</span> +<span class="r-out co"><span class="r-pr">#></span> 309: 93.8092 -6.1122 -0.1643 2.1777 -0.9849 3.9948 4.2297 0.4201 0.2948 0.1804 5.4001 1.6998</span> +<span class="r-out co"><span class="r-pr">#></span> 310: 93.8080 -6.1142 -0.1642 2.1780 -0.9850 3.9976 4.2436 0.4197 0.2951 0.1803 5.4016 1.6989</span> +<span class="r-out co"><span class="r-pr">#></span> 311: 93.8094 -6.1164 -0.1641 2.1784 -0.9851 4.0015 4.2552 0.4194 0.2952 0.1803 5.4033 1.6978</span> +<span class="r-out co"><span class="r-pr">#></span> 312: 93.8107 -6.1184 -0.1640 2.1788 -0.9851 4.0006 4.2628 0.4190 0.2954 0.1802 5.4042 1.6972</span> +<span class="r-out co"><span class="r-pr">#></span> 313: 93.8118 -6.1190 -0.1640 2.1789 -0.9851 3.9991 4.2638 0.4186 0.2955 0.1802 5.4053 1.6967</span> +<span class="r-out co"><span class="r-pr">#></span> 314: 93.8139 -6.1188 -0.1639 2.1791 -0.9851 4.0019 4.2619 0.4183 0.2956 0.1802 5.4049 1.6966</span> +<span class="r-out co"><span class="r-pr">#></span> 315: 93.8152 -6.1173 -0.1639 2.1792 -0.9851 4.0111 4.2553 0.4179 0.2957 0.1802 5.4052 1.6966</span> +<span class="r-out co"><span class="r-pr">#></span> 316: 93.8178 -6.1158 -0.1639 2.1792 -0.9851 4.0073 4.2498 0.4175 0.2957 0.1802 5.4050 1.6966</span> +<span class="r-out co"><span class="r-pr">#></span> 317: 93.8205 -6.1155 -0.1639 2.1792 -0.9851 3.9999 4.2491 0.4172 0.2957 0.1802 5.4048 1.6963</span> +<span class="r-out co"><span class="r-pr">#></span> 318: 93.8216 -6.1145 -0.1639 2.1792 -0.9850 3.9961 4.2438 0.4168 0.2957 0.1802 5.4031 1.6961</span> +<span class="r-out co"><span class="r-pr">#></span> 319: 93.8241 -6.1143 -0.1639 2.1792 -0.9849 4.0009 4.2412 0.4164 0.2958 0.1801 5.4004 1.6956</span> +<span class="r-out co"><span class="r-pr">#></span> 320: 93.8257 -6.1142 -0.1639 2.1792 -0.9849 4.0018 4.2380 0.4160 0.2958 0.1801 5.3986 1.6952</span> +<span class="r-out co"><span class="r-pr">#></span> 321: 93.8280 -6.1134 -0.1639 2.1792 -0.9849 4.0055 4.2339 0.4156 0.2959 0.1802 5.3966 1.6950</span> +<span class="r-out co"><span class="r-pr">#></span> 322: 93.8299 -6.1122 -0.1639 2.1793 -0.9848 4.0075 4.2274 0.4152 0.2959 0.1802 5.3969 1.6948</span> +<span class="r-out co"><span class="r-pr">#></span> 323: 93.8318 -6.1123 -0.1639 2.1794 -0.9848 4.0087 4.2257 0.4149 0.2960 0.1802 5.3980 1.6941</span> +<span class="r-out co"><span class="r-pr">#></span> 324: 93.8352 -6.1098 -0.1639 2.1795 -0.9848 4.0123 4.2136 0.4145 0.2960 0.1802 5.3988 1.6936</span> +<span class="r-out co"><span class="r-pr">#></span> 325: 93.8374 -6.1072 -0.1638 2.1796 -0.9848 4.0230 4.2005 0.4142 0.2961 0.1802 5.3991 1.6933</span> +<span class="r-out co"><span class="r-pr">#></span> 326: 93.8410 -6.1050 -0.1637 2.1796 -0.9849 4.0327 4.1891 0.4139 0.2963 0.1802 5.4004 1.6927</span> +<span class="r-out co"><span class="r-pr">#></span> 327: 93.8457 -6.1023 -0.1637 2.1796 -0.9849 4.0327 4.1767 0.4135 0.2964 0.1802 5.4013 1.6922</span> +<span class="r-out co"><span class="r-pr">#></span> 328: 93.8493 -6.1017 -0.1637 2.1797 -0.9850 4.0440 4.1730 0.4131 0.2964 0.1802 5.4019 1.6915</span> +<span class="r-out co"><span class="r-pr">#></span> 329: 93.8515 -6.1001 -0.1637 2.1799 -0.9851 4.0556 4.1648 0.4128 0.2963 0.1803 5.4017 1.6912</span> +<span class="r-out co"><span class="r-pr">#></span> 330: 93.8541 -6.1001 -0.1636 2.1800 -0.9852 4.0606 4.1631 0.4124 0.2962 0.1804 5.4025 1.6912</span> +<span class="r-out co"><span class="r-pr">#></span> 331: 93.8539 -6.0994 -0.1635 2.1801 -0.9854 4.0654 4.1584 0.4120 0.2961 0.1805 5.4025 1.6907</span> +<span class="r-out co"><span class="r-pr">#></span> 332: 93.8536 -6.0999 -0.1634 2.1803 -0.9854 4.0696 4.1601 0.4116 0.2960 0.1808 5.4027 1.6904</span> +<span class="r-out co"><span class="r-pr">#></span> 333: 93.8531 -6.1002 -0.1633 2.1806 -0.9853 4.0682 4.1646 0.4112 0.2960 0.1810 5.4038 1.6893</span> +<span class="r-out co"><span class="r-pr">#></span> 334: 93.8543 -6.1005 -0.1632 2.1809 -0.9852 4.0771 4.1690 0.4108 0.2960 0.1812 5.4040 1.6883</span> +<span class="r-out co"><span class="r-pr">#></span> 335: 93.8552 -6.1010 -0.1631 2.1813 -0.9851 4.0888 4.1775 0.4104 0.2960 0.1813 5.4044 1.6878</span> +<span class="r-out co"><span class="r-pr">#></span> 336: 93.8555 -6.1016 -0.1630 2.1817 -0.9850 4.0969 4.1858 0.4099 0.2961 0.1814 5.4046 1.6873</span> +<span class="r-out co"><span class="r-pr">#></span> 337: 93.8553 -6.1025 -0.1628 2.1820 -0.9849 4.1152 4.1921 0.4094 0.2962 0.1815 5.4070 1.6863</span> +<span class="r-out co"><span class="r-pr">#></span> 338: 93.8553 -6.1018 -0.1626 2.1824 -0.9848 4.1314 4.1904 0.4090 0.2963 0.1816 5.4080 1.6852</span> +<span class="r-out co"><span class="r-pr">#></span> 339: 93.8567 -6.1004 -0.1625 2.1828 -0.9847 4.1449 4.1855 0.4087 0.2964 0.1817 5.4087 1.6841</span> +<span class="r-out co"><span class="r-pr">#></span> 340: 93.8582 -6.0987 -0.1623 2.1832 -0.9846 4.1603 4.1799 0.4083 0.2965 0.1819 5.4086 1.6832</span> +<span class="r-out co"><span class="r-pr">#></span> 341: 93.8589 -6.0962 -0.1620 2.1836 -0.9844 4.1692 4.1694 0.4079 0.2965 0.1820 5.4102 1.6828</span> +<span class="r-out co"><span class="r-pr">#></span> 342: 93.8583 -6.0932 -0.1618 2.1841 -0.9844 4.1729 4.1563 0.4075 0.2966 0.1821 5.4117 1.6821</span> +<span class="r-out co"><span class="r-pr">#></span> 343: 93.8590 -6.0906 -0.1615 2.1845 -0.9844 4.1840 4.1447 0.4071 0.2966 0.1822 5.4125 1.6819</span> +<span class="r-out co"><span class="r-pr">#></span> 344: 93.8582 -6.0890 -0.1613 2.1851 -0.9845 4.1860 4.1347 0.4068 0.2968 0.1826 5.4135 1.6814</span> +<span class="r-out co"><span class="r-pr">#></span> 345: 93.8576 -6.0876 -0.1610 2.1857 -0.9846 4.1889 4.1252 0.4064 0.2969 0.1829 5.4143 1.6810</span> +<span class="r-out co"><span class="r-pr">#></span> 346: 93.8549 -6.0853 -0.1608 2.1862 -0.9845 4.1925 4.1121 0.4061 0.2969 0.1832 5.4157 1.6803</span> +<span class="r-out co"><span class="r-pr">#></span> 347: 93.8540 -6.0829 -0.1605 2.1867 -0.9845 4.2031 4.0990 0.4058 0.2970 0.1834 5.4158 1.6803</span> +<span class="r-out co"><span class="r-pr">#></span> 348: 93.8516 -6.0814 -0.1602 2.1873 -0.9845 4.2169 4.0885 0.4055 0.2971 0.1836 5.4174 1.6801</span> +<span class="r-out co"><span class="r-pr">#></span> 349: 93.8505 -6.0797 -0.1600 2.1879 -0.9845 4.2253 4.0779 0.4052 0.2971 0.1837 5.4190 1.6799</span> +<span class="r-out co"><span class="r-pr">#></span> 350: 93.8512 -6.0773 -0.1597 2.1885 -0.9845 4.2268 4.0657 0.4049 0.2972 0.1839 5.4209 1.6797</span> +<span class="r-out co"><span class="r-pr">#></span> 351: 93.8507 -6.0754 -0.1595 2.1890 -0.9845 4.2245 4.0559 0.4046 0.2972 0.1840 5.4230 1.6794</span> +<span class="r-out co"><span class="r-pr">#></span> 352: 93.8490 -6.0736 -0.1592 2.1896 -0.9845 4.2296 4.0474 0.4044 0.2973 0.1841 5.4252 1.6790</span> +<span class="r-out co"><span class="r-pr">#></span> 353: 93.8460 -6.0718 -0.1589 2.1901 -0.9845 4.2356 4.0374 0.4042 0.2973 0.1843 5.4272 1.6790</span> +<span class="r-out co"><span class="r-pr">#></span> 354: 93.8437 -6.0695 -0.1586 2.1906 -0.9845 4.2408 4.0255 0.4041 0.2973 0.1844 5.4303 1.6787</span> +<span class="r-out co"><span class="r-pr">#></span> 355: 93.8420 -6.0679 -0.1584 2.1912 -0.9844 4.2428 4.0166 0.4040 0.2973 0.1845 5.4342 1.6785</span> +<span class="r-out co"><span class="r-pr">#></span> 356: 93.8413 -6.0666 -0.1581 2.1916 -0.9843 4.2418 4.0072 0.4040 0.2973 0.1845 5.4348 1.6792</span> +<span class="r-out co"><span class="r-pr">#></span> 357: 93.8406 -6.0650 -0.1578 2.1921 -0.9844 4.2531 3.9973 0.4040 0.2973 0.1846 5.4350 1.6798</span> +<span class="r-out co"><span class="r-pr">#></span> 358: 93.8404 -6.0639 -0.1575 2.1926 -0.9844 4.2596 3.9901 0.4040 0.2973 0.1846 5.4357 1.6805</span> +<span class="r-out co"><span class="r-pr">#></span> 359: 93.8373 -6.0630 -0.1572 2.1931 -0.9845 4.2724 3.9820 0.4039 0.2973 0.1848 5.4368 1.6816</span> +<span class="r-out co"><span class="r-pr">#></span> 360: 93.8347 -6.0622 -0.1569 2.1936 -0.9845 4.2788 3.9747 0.4039 0.2973 0.1849 5.4377 1.6824</span> +<span class="r-out co"><span class="r-pr">#></span> 361: 93.8327 -6.0626 -0.1566 2.1942 -0.9846 4.2919 3.9749 0.4038 0.2973 0.1850 5.4382 1.6831</span> +<span class="r-out co"><span class="r-pr">#></span> 362: 93.8326 -6.0629 -0.1562 2.1947 -0.9846 4.2989 3.9737 0.4038 0.2973 0.1850 5.4408 1.6838</span> +<span class="r-out co"><span class="r-pr">#></span> 363: 93.8316 -6.0629 -0.1559 2.1953 -0.9846 4.3007 3.9725 0.4037 0.2972 0.1850 5.4420 1.6842</span> +<span class="r-out co"><span class="r-pr">#></span> 364: 93.8317 -6.0629 -0.1556 2.1957 -0.9846 4.2910 3.9739 0.4038 0.2971 0.1850 5.4430 1.6840</span> +<span class="r-out co"><span class="r-pr">#></span> 365: 93.8317 -6.0629 -0.1553 2.1962 -0.9846 4.2878 3.9759 0.4040 0.2967 0.1849 5.4441 1.6839</span> +<span class="r-out co"><span class="r-pr">#></span> 366: 93.8319 -6.0633 -0.1549 2.1966 -0.9845 4.2870 3.9823 0.4042 0.2963 0.1849 5.4461 1.6839</span> +<span class="r-out co"><span class="r-pr">#></span> 367: 93.8320 -6.0636 -0.1546 2.1971 -0.9845 4.2828 3.9850 0.4042 0.2959 0.1849 5.4479 1.6843</span> +<span class="r-out co"><span class="r-pr">#></span> 368: 93.8312 -6.0635 -0.1544 2.1975 -0.9844 4.2781 3.9859 0.4043 0.2955 0.1849 5.4475 1.6841</span> +<span class="r-out co"><span class="r-pr">#></span> 369: 93.8301 -6.0640 -0.1541 2.1979 -0.9844 4.2760 3.9891 0.4043 0.2953 0.1850 5.4472 1.6835</span> +<span class="r-out co"><span class="r-pr">#></span> 370: 93.8306 -6.0651 -0.1539 2.1983 -0.9844 4.2690 3.9967 0.4042 0.2950 0.1850 5.4484 1.6829</span> +<span class="r-out co"><span class="r-pr">#></span> 371: 93.8312 -6.0669 -0.1536 2.1988 -0.9845 4.2613 4.0111 0.4042 0.2947 0.1851 5.4494 1.6822</span> +<span class="r-out co"><span class="r-pr">#></span> 372: 93.8312 -6.0681 -0.1533 2.1992 -0.9845 4.2585 4.0252 0.4042 0.2945 0.1852 5.4513 1.6817</span> +<span class="r-out co"><span class="r-pr">#></span> 373: 93.8307 -6.0681 -0.1531 2.1996 -0.9846 4.2605 4.0284 0.4042 0.2943 0.1853 5.4523 1.6815</span> +<span class="r-out co"><span class="r-pr">#></span> 374: 93.8305 -6.0678 -0.1529 2.1999 -0.9846 4.2676 4.0279 0.4040 0.2942 0.1853 5.4533 1.6816</span> +<span class="r-out co"><span class="r-pr">#></span> 375: 93.8313 -6.0673 -0.1528 2.2002 -0.9846 4.2708 4.0232 0.4038 0.2940 0.1854 5.4543 1.6813</span> +<span class="r-out co"><span class="r-pr">#></span> 376: 93.8310 -6.0672 -0.1527 2.2004 -0.9846 4.2775 4.0214 0.4037 0.2938 0.1855 5.4538 1.6809</span> +<span class="r-out co"><span class="r-pr">#></span> 377: 93.8298 -6.0666 -0.1526 2.2007 -0.9846 4.2787 4.0166 0.4035 0.2937 0.1856 5.4532 1.6806</span> +<span class="r-out co"><span class="r-pr">#></span> 378: 93.8276 -6.0664 -0.1525 2.2009 -0.9846 4.2781 4.0135 0.4033 0.2935 0.1857 5.4538 1.6801</span> +<span class="r-out co"><span class="r-pr">#></span> 379: 93.8262 -6.0671 -0.1524 2.2012 -0.9846 4.2800 4.0157 0.4031 0.2932 0.1857 5.4530 1.6803</span> +<span class="r-out co"><span class="r-pr">#></span> 380: 93.8243 -6.0675 -0.1523 2.2015 -0.9846 4.2735 4.0168 0.4029 0.2929 0.1857 5.4523 1.6803</span> +<span class="r-out co"><span class="r-pr">#></span> 381: 93.8233 -6.0677 -0.1522 2.2017 -0.9845 4.2670 4.0189 0.4027 0.2926 0.1858 5.4517 1.6798</span> +<span class="r-out co"><span class="r-pr">#></span> 382: 93.8229 -6.0674 -0.1521 2.2019 -0.9845 4.2655 4.0211 0.4025 0.2924 0.1858 5.4510 1.6794</span> +<span class="r-out co"><span class="r-pr">#></span> 383: 93.8196 -6.0681 -0.1521 2.2021 -0.9843 4.2696 4.0291 0.4023 0.2922 0.1859 5.4504 1.6788</span> +<span class="r-out co"><span class="r-pr">#></span> 384: 93.8174 -6.0688 -0.1520 2.2023 -0.9842 4.2851 4.0333 0.4021 0.2919 0.1860 5.4500 1.6783</span> +<span class="r-out co"><span class="r-pr">#></span> 385: 93.8156 -6.0682 -0.1518 2.2028 -0.9840 4.3056 4.0305 0.4019 0.2920 0.1862 5.4503 1.6774</span> +<span class="r-out co"><span class="r-pr">#></span> 386: 93.8145 -6.0684 -0.1516 2.2032 -0.9838 4.3195 4.0302 0.4016 0.2920 0.1863 5.4499 1.6765</span> +<span class="r-out co"><span class="r-pr">#></span> 387: 93.8121 -6.0679 -0.1514 2.2036 -0.9837 4.3290 4.0272 0.4014 0.2920 0.1864 5.4501 1.6756</span> +<span class="r-out co"><span class="r-pr">#></span> 388: 93.8105 -6.0676 -0.1513 2.2040 -0.9835 4.3393 4.0267 0.4011 0.2920 0.1865 5.4509 1.6751</span> +<span class="r-out co"><span class="r-pr">#></span> 389: 93.8089 -6.0664 -0.1510 2.2045 -0.9833 4.3458 4.0224 0.4009 0.2920 0.1865 5.4512 1.6746</span> +<span class="r-out co"><span class="r-pr">#></span> 390: 93.8080 -6.0658 -0.1508 2.2049 -0.9832 4.3422 4.0199 0.4007 0.2920 0.1866 5.4514 1.6744</span> +<span class="r-out co"><span class="r-pr">#></span> 391: 93.8077 -6.0669 -0.1507 2.2053 -0.9831 4.3500 4.0277 0.4007 0.2920 0.1867 5.4511 1.6740</span> +<span class="r-out co"><span class="r-pr">#></span> 392: 93.8069 -6.0676 -0.1505 2.2056 -0.9831 4.3525 4.0326 0.4006 0.2920 0.1868 5.4500 1.6733</span> +<span class="r-out co"><span class="r-pr">#></span> 393: 93.8072 -6.0678 -0.1504 2.2059 -0.9830 4.3562 4.0344 0.4005 0.2920 0.1868 5.4491 1.6725</span> +<span class="r-out co"><span class="r-pr">#></span> 394: 93.8083 -6.0684 -0.1503 2.2061 -0.9829 4.3577 4.0386 0.4004 0.2920 0.1869 5.4493 1.6716</span> +<span class="r-out co"><span class="r-pr">#></span> 395: 93.8086 -6.0685 -0.1501 2.2064 -0.9828 4.3574 4.0394 0.4003 0.2920 0.1869 5.4493 1.6709</span> +<span class="r-out co"><span class="r-pr">#></span> 396: 93.8078 -6.0677 -0.1500 2.2067 -0.9827 4.3591 4.0355 0.4002 0.2921 0.1870 5.4493 1.6707</span> +<span class="r-out co"><span class="r-pr">#></span> 397: 93.8064 -6.0668 -0.1499 2.2071 -0.9825 4.3621 4.0317 0.4000 0.2922 0.1871 5.4495 1.6704</span> +<span class="r-out co"><span class="r-pr">#></span> 398: 93.8058 -6.0661 -0.1499 2.2073 -0.9823 4.3701 4.0285 0.3999 0.2923 0.1872 5.4491 1.6699</span> +<span class="r-out co"><span class="r-pr">#></span> 399: 93.8057 -6.0651 -0.1498 2.2075 -0.9822 4.3803 4.0243 0.3997 0.2924 0.1872 5.4485 1.6699</span> +<span class="r-out co"><span class="r-pr">#></span> 400: 93.8057 -6.0647 -0.1498 2.2076 -0.9820 4.3854 4.0225 0.3996 0.2924 0.1872 5.4488 1.6699</span> +<span class="r-out co"><span class="r-pr">#></span> 401: 93.8059 -6.0635 -0.1498 2.2078 -0.9819 4.3939 4.0178 0.3995 0.2925 0.1873 5.4491 1.6702</span> +<span class="r-out co"><span class="r-pr">#></span> 402: 93.8063 -6.0621 -0.1498 2.2079 -0.9818 4.4033 4.0120 0.3993 0.2926 0.1875 5.4492 1.6704</span> +<span class="r-out co"><span class="r-pr">#></span> 403: 93.8055 -6.0609 -0.1498 2.2080 -0.9816 4.4098 4.0069 0.3992 0.2926 0.1876 5.4494 1.6703</span> +<span class="r-out co"><span class="r-pr">#></span> 404: 93.8040 -6.0608 -0.1499 2.2081 -0.9815 4.4153 4.0050 0.3991 0.2927 0.1877 5.4494 1.6701</span> +<span class="r-out co"><span class="r-pr">#></span> 405: 93.8030 -6.0604 -0.1499 2.2082 -0.9814 4.4181 4.0047 0.3990 0.2928 0.1879 5.4491 1.6700</span> +<span class="r-out co"><span class="r-pr">#></span> 406: 93.8002 -6.0597 -0.1499 2.2083 -0.9812 4.4257 4.0025 0.3989 0.2928 0.1880 5.4498 1.6702</span> +<span class="r-out co"><span class="r-pr">#></span> 407: 93.7969 -6.0593 -0.1500 2.2085 -0.9810 4.4343 3.9994 0.3988 0.2928 0.1881 5.4514 1.6703</span> +<span class="r-out co"><span class="r-pr">#></span> 408: 93.7947 -6.0582 -0.1499 2.2087 -0.9809 4.4509 3.9936 0.3987 0.2927 0.1882 5.4526 1.6704</span> +<span class="r-out co"><span class="r-pr">#></span> 409: 93.7929 -6.0579 -0.1499 2.2088 -0.9807 4.4584 3.9918 0.3987 0.2926 0.1882 5.4537 1.6707</span> +<span class="r-out co"><span class="r-pr">#></span> 410: 93.7896 -6.0593 -0.1499 2.2089 -0.9807 4.4664 4.0002 0.3987 0.2925 0.1883 5.4560 1.6705</span> +<span class="r-out co"><span class="r-pr">#></span> 411: 93.7875 -6.0601 -0.1499 2.2090 -0.9807 4.4626 4.0057 0.3987 0.2924 0.1883 5.4567 1.6705</span> +<span class="r-out co"><span class="r-pr">#></span> 412: 93.7862 -6.0602 -0.1499 2.2091 -0.9808 4.4574 4.0095 0.3986 0.2923 0.1884 5.4565 1.6706</span> +<span class="r-out co"><span class="r-pr">#></span> 413: 93.7858 -6.0606 -0.1498 2.2092 -0.9808 4.4527 4.0146 0.3986 0.2922 0.1885 5.4561 1.6708</span> +<span class="r-out co"><span class="r-pr">#></span> 414: 93.7859 -6.0615 -0.1498 2.2093 -0.9808 4.4451 4.0211 0.3987 0.2921 0.1885 5.4574 1.6708</span> +<span class="r-out co"><span class="r-pr">#></span> 415: 93.7864 -6.0629 -0.1498 2.2092 -0.9808 4.4443 4.0298 0.3986 0.2921 0.1885 5.4576 1.6707</span> +<span class="r-out co"><span class="r-pr">#></span> 416: 93.7851 -6.0639 -0.1498 2.2092 -0.9808 4.4462 4.0362 0.3985 0.2920 0.1884 5.4575 1.6706</span> +<span class="r-out co"><span class="r-pr">#></span> 417: 93.7820 -6.0644 -0.1499 2.2092 -0.9808 4.4425 4.0387 0.3985 0.2920 0.1884 5.4577 1.6703</span> +<span class="r-out co"><span class="r-pr">#></span> 418: 93.7801 -6.0652 -0.1499 2.2093 -0.9808 4.4365 4.0420 0.3985 0.2920 0.1883 5.4589 1.6702</span> +<span class="r-out co"><span class="r-pr">#></span> 419: 93.7799 -6.0648 -0.1499 2.2094 -0.9807 4.4303 4.0418 0.3984 0.2921 0.1883 5.4596 1.6703</span> +<span class="r-out co"><span class="r-pr">#></span> 420: 93.7797 -6.0641 -0.1498 2.2095 -0.9807 4.4216 4.0383 0.3983 0.2921 0.1884 5.4607 1.6702</span> +<span class="r-out co"><span class="r-pr">#></span> 421: 93.7803 -6.0641 -0.1498 2.2096 -0.9808 4.4120 4.0396 0.3983 0.2922 0.1885 5.4621 1.6702</span> +<span class="r-out co"><span class="r-pr">#></span> 422: 93.7806 -6.0638 -0.1498 2.2097 -0.9809 4.4017 4.0373 0.3981 0.2923 0.1885 5.4635 1.6702</span> +<span class="r-out co"><span class="r-pr">#></span> 423: 93.7800 -6.0636 -0.1498 2.2098 -0.9810 4.3948 4.0339 0.3981 0.2923 0.1885 5.4640 1.6701</span> +<span class="r-out co"><span class="r-pr">#></span> 424: 93.7789 -6.0638 -0.1498 2.2099 -0.9810 4.3884 4.0336 0.3980 0.2924 0.1885 5.4651 1.6700</span> +<span class="r-out co"><span class="r-pr">#></span> 425: 93.7774 -6.0628 -0.1498 2.2101 -0.9810 4.3814 4.0271 0.3978 0.2925 0.1884 5.4666 1.6699</span> +<span class="r-out co"><span class="r-pr">#></span> 426: 93.7755 -6.0619 -0.1498 2.2102 -0.9811 4.3841 4.0221 0.3977 0.2925 0.1884 5.4693 1.6697</span> +<span class="r-out co"><span class="r-pr">#></span> 427: 93.7753 -6.0612 -0.1498 2.2103 -0.9810 4.3785 4.0167 0.3975 0.2926 0.1883 5.4712 1.6696</span> +<span class="r-out co"><span class="r-pr">#></span> 428: 93.7741 -6.0613 -0.1498 2.2104 -0.9810 4.3767 4.0161 0.3973 0.2926 0.1882 5.4729 1.6696</span> +<span class="r-out co"><span class="r-pr">#></span> 429: 93.7717 -6.0613 -0.1498 2.2105 -0.9810 4.3744 4.0158 0.3971 0.2926 0.1880 5.4743 1.6694</span> +<span class="r-out co"><span class="r-pr">#></span> 430: 93.7690 -6.0619 -0.1498 2.2106 -0.9809 4.3744 4.0189 0.3969 0.2926 0.1879 5.4753 1.6692</span> +<span class="r-out co"><span class="r-pr">#></span> 431: 93.7668 -6.0615 -0.1498 2.2107 -0.9809 4.3709 4.0174 0.3967 0.2925 0.1878 5.4762 1.6691</span> +<span class="r-out co"><span class="r-pr">#></span> 432: 93.7656 -6.0619 -0.1498 2.2108 -0.9809 4.3710 4.0173 0.3966 0.2926 0.1878 5.4770 1.6688</span> +<span class="r-out co"><span class="r-pr">#></span> 433: 93.7632 -6.0625 -0.1498 2.2108 -0.9809 4.3689 4.0204 0.3964 0.2926 0.1877 5.4774 1.6687</span> +<span class="r-out co"><span class="r-pr">#></span> 434: 93.7624 -6.0621 -0.1498 2.2109 -0.9808 4.3687 4.0178 0.3962 0.2926 0.1876 5.4774 1.6683</span> +<span class="r-out co"><span class="r-pr">#></span> 435: 93.7608 -6.0622 -0.1497 2.2111 -0.9808 4.3714 4.0182 0.3961 0.2927 0.1875 5.4777 1.6679</span> +<span class="r-out co"><span class="r-pr">#></span> 436: 93.7586 -6.0622 -0.1498 2.2112 -0.9808 4.3695 4.0178 0.3959 0.2928 0.1874 5.4784 1.6679</span> +<span class="r-out co"><span class="r-pr">#></span> 437: 93.7558 -6.0622 -0.1498 2.2114 -0.9809 4.3658 4.0167 0.3957 0.2928 0.1873 5.4795 1.6678</span> +<span class="r-out co"><span class="r-pr">#></span> 438: 93.7519 -6.0627 -0.1499 2.2115 -0.9808 4.3601 4.0183 0.3955 0.2928 0.1872 5.4807 1.6674</span> +<span class="r-out co"><span class="r-pr">#></span> 439: 93.7478 -6.0618 -0.1499 2.2115 -0.9807 4.3538 4.0133 0.3952 0.2928 0.1871 5.4814 1.6672</span> +<span class="r-out co"><span class="r-pr">#></span> 440: 93.7449 -6.0612 -0.1499 2.2117 -0.9805 4.3504 4.0103 0.3951 0.2928 0.1870 5.4820 1.6669</span> +<span class="r-out co"><span class="r-pr">#></span> 441: 93.7433 -6.0608 -0.1499 2.2117 -0.9805 4.3438 4.0077 0.3949 0.2928 0.1869 5.4818 1.6666</span> +<span class="r-out co"><span class="r-pr">#></span> 442: 93.7417 -6.0604 -0.1500 2.2118 -0.9805 4.3354 4.0058 0.3947 0.2927 0.1868 5.4824 1.6666</span> +<span class="r-out co"><span class="r-pr">#></span> 443: 93.7407 -6.0604 -0.1500 2.2119 -0.9805 4.3281 4.0046 0.3946 0.2927 0.1867 5.4832 1.6667</span> +<span class="r-out co"><span class="r-pr">#></span> 444: 93.7397 -6.0608 -0.1500 2.2118 -0.9805 4.3180 4.0069 0.3944 0.2928 0.1866 5.4857 1.6664</span> +<span class="r-out co"><span class="r-pr">#></span> 445: 93.7387 -6.0613 -0.1501 2.2118 -0.9805 4.3092 4.0085 0.3942 0.2929 0.1866 5.4866 1.6663</span> +<span class="r-out co"><span class="r-pr">#></span> 446: 93.7376 -6.0612 -0.1502 2.2117 -0.9805 4.3022 4.0075 0.3939 0.2930 0.1865 5.4866 1.6660</span> +<span class="r-out co"><span class="r-pr">#></span> 447: 93.7375 -6.0613 -0.1503 2.2116 -0.9806 4.2981 4.0076 0.3937 0.2931 0.1865 5.4863 1.6658</span> +<span class="r-out co"><span class="r-pr">#></span> 448: 93.7388 -6.0617 -0.1504 2.2115 -0.9806 4.2970 4.0087 0.3935 0.2932 0.1864 5.4870 1.6658</span> +<span class="r-out co"><span class="r-pr">#></span> 449: 93.7400 -6.0617 -0.1504 2.2115 -0.9807 4.2904 4.0069 0.3933 0.2933 0.1864 5.4880 1.6655</span> +<span class="r-out co"><span class="r-pr">#></span> 450: 93.7414 -6.0623 -0.1505 2.2113 -0.9808 4.2829 4.0095 0.3930 0.2935 0.1863 5.4880 1.6653</span> +<span class="r-out co"><span class="r-pr">#></span> 451: 93.7426 -6.0634 -0.1506 2.2112 -0.9808 4.2797 4.0146 0.3928 0.2936 0.1863 5.4877 1.6655</span> +<span class="r-out co"><span class="r-pr">#></span> 452: 93.7447 -6.0642 -0.1507 2.2110 -0.9809 4.2770 4.0171 0.3926 0.2938 0.1862 5.4876 1.6657</span> +<span class="r-out co"><span class="r-pr">#></span> 453: 93.7465 -6.0644 -0.1508 2.2108 -0.9810 4.2698 4.0184 0.3924 0.2940 0.1862 5.4877 1.6652</span> +<span class="r-out co"><span class="r-pr">#></span> 454: 93.7478 -6.0645 -0.1509 2.2106 -0.9810 4.2657 4.0182 0.3922 0.2941 0.1861 5.4874 1.6648</span> +<span class="r-out co"><span class="r-pr">#></span> 455: 93.7486 -6.0650 -0.1511 2.2104 -0.9811 4.2656 4.0203 0.3921 0.2943 0.1861 5.4871 1.6644</span> +<span class="r-out co"><span class="r-pr">#></span> 456: 93.7485 -6.0659 -0.1512 2.2102 -0.9812 4.2646 4.0240 0.3920 0.2945 0.1860 5.4869 1.6641</span> +<span class="r-out co"><span class="r-pr">#></span> 457: 93.7487 -6.0668 -0.1514 2.2099 -0.9813 4.2613 4.0277 0.3919 0.2946 0.1860 5.4866 1.6640</span> +<span class="r-out co"><span class="r-pr">#></span> 458: 93.7484 -6.0667 -0.1515 2.2097 -0.9812 4.2586 4.0263 0.3918 0.2947 0.1859 5.4854 1.6639</span> +<span class="r-out co"><span class="r-pr">#></span> 459: 93.7468 -6.0661 -0.1517 2.2095 -0.9812 4.2565 4.0225 0.3917 0.2948 0.1858 5.4853 1.6639</span> +<span class="r-out co"><span class="r-pr">#></span> 460: 93.7458 -6.0652 -0.1518 2.2093 -0.9812 4.2548 4.0171 0.3916 0.2950 0.1858 5.4843 1.6638</span> +<span class="r-out co"><span class="r-pr">#></span> 461: 93.7435 -6.0645 -0.1519 2.2091 -0.9811 4.2554 4.0121 0.3914 0.2951 0.1858 5.4843 1.6637</span> +<span class="r-out co"><span class="r-pr">#></span> 462: 93.7421 -6.0637 -0.1521 2.2089 -0.9811 4.2509 4.0079 0.3913 0.2953 0.1857 5.4840 1.6638</span> +<span class="r-out co"><span class="r-pr">#></span> 463: 93.7406 -6.0630 -0.1522 2.2088 -0.9810 4.2534 4.0036 0.3912 0.2955 0.1857 5.4834 1.6640</span> +<span class="r-out co"><span class="r-pr">#></span> 464: 93.7406 -6.0622 -0.1524 2.2086 -0.9810 4.2548 3.9986 0.3911 0.2956 0.1857 5.4828 1.6639</span> +<span class="r-out co"><span class="r-pr">#></span> 465: 93.7404 -6.0617 -0.1525 2.2084 -0.9810 4.2511 3.9955 0.3910 0.2958 0.1857 5.4828 1.6638</span> +<span class="r-out co"><span class="r-pr">#></span> 466: 93.7414 -6.0610 -0.1527 2.2080 -0.9809 4.2468 3.9918 0.3910 0.2959 0.1857 5.4812 1.6640</span> +<span class="r-out co"><span class="r-pr">#></span> 467: 93.7419 -6.0606 -0.1529 2.2077 -0.9810 4.2446 3.9885 0.3909 0.2960 0.1858 5.4799 1.6642</span> +<span class="r-out co"><span class="r-pr">#></span> 468: 93.7427 -6.0604 -0.1531 2.2074 -0.9809 4.2473 3.9872 0.3909 0.2961 0.1858 5.4790 1.6643</span> +<span class="r-out co"><span class="r-pr">#></span> 469: 93.7435 -6.0608 -0.1532 2.2073 -0.9810 4.2457 3.9891 0.3907 0.2963 0.1858 5.4789 1.6641</span> +<span class="r-out co"><span class="r-pr">#></span> 470: 93.7442 -6.0611 -0.1533 2.2071 -0.9811 4.2443 3.9895 0.3905 0.2965 0.1858 5.4785 1.6640</span> +<span class="r-out co"><span class="r-pr">#></span> 471: 93.7443 -6.0618 -0.1534 2.2070 -0.9812 4.2415 3.9932 0.3903 0.2967 0.1858 5.4773 1.6639</span> +<span class="r-out co"><span class="r-pr">#></span> 472: 93.7433 -6.0624 -0.1535 2.2069 -0.9812 4.2414 3.9958 0.3901 0.2969 0.1858 5.4765 1.6637</span> +<span class="r-out co"><span class="r-pr">#></span> 473: 93.7421 -6.0621 -0.1536 2.2067 -0.9811 4.2330 3.9962 0.3899 0.2970 0.1858 5.4762 1.6637</span> +<span class="r-out co"><span class="r-pr">#></span> 474: 93.7415 -6.0621 -0.1537 2.2066 -0.9812 4.2263 3.9968 0.3897 0.2972 0.1858 5.4755 1.6638</span> +<span class="r-out co"><span class="r-pr">#></span> 475: 93.7396 -6.0621 -0.1538 2.2066 -0.9812 4.2261 3.9956 0.3895 0.2973 0.1859 5.4751 1.6637</span> +<span class="r-out co"><span class="r-pr">#></span> 476: 93.7373 -6.0626 -0.1539 2.2065 -0.9811 4.2265 3.9976 0.3893 0.2975 0.1859 5.4743 1.6634</span> +<span class="r-out co"><span class="r-pr">#></span> 477: 93.7357 -6.0623 -0.1540 2.2063 -0.9811 4.2222 3.9953 0.3891 0.2976 0.1859 5.4741 1.6635</span> +<span class="r-out co"><span class="r-pr">#></span> 478: 93.7345 -6.0620 -0.1541 2.2062 -0.9811 4.2165 3.9939 0.3889 0.2978 0.1860 5.4745 1.6638</span> +<span class="r-out co"><span class="r-pr">#></span> 479: 93.7341 -6.0615 -0.1542 2.2062 -0.9812 4.2122 3.9916 0.3887 0.2979 0.1860 5.4751 1.6637</span> +<span class="r-out co"><span class="r-pr">#></span> 480: 93.7338 -6.0619 -0.1543 2.2061 -0.9812 4.2084 3.9932 0.3885 0.2980 0.1860 5.4753 1.6635</span> +<span class="r-out co"><span class="r-pr">#></span> 481: 93.7336 -6.0618 -0.1544 2.2060 -0.9812 4.2066 3.9945 0.3883 0.2981 0.1860 5.4748 1.6637</span> +<span class="r-out co"><span class="r-pr">#></span> 482: 93.7340 -6.0622 -0.1545 2.2058 -0.9812 4.2069 3.9969 0.3882 0.2983 0.1860 5.4741 1.6636</span> +<span class="r-out co"><span class="r-pr">#></span> 483: 93.7328 -6.0627 -0.1547 2.2057 -0.9813 4.2062 3.9992 0.3879 0.2985 0.1861 5.4739 1.6636</span> +<span class="r-out co"><span class="r-pr">#></span> 484: 93.7323 -6.0629 -0.1547 2.2056 -0.9813 4.2075 3.9995 0.3877 0.2987 0.1861 5.4730 1.6638</span> +<span class="r-out co"><span class="r-pr">#></span> 485: 93.7326 -6.0634 -0.1548 2.2055 -0.9814 4.2045 4.0013 0.3875 0.2989 0.1862 5.4727 1.6637</span> +<span class="r-out co"><span class="r-pr">#></span> 486: 93.7320 -6.0632 -0.1549 2.2055 -0.9814 4.2084 3.9989 0.3872 0.2991 0.1863 5.4718 1.6635</span> +<span class="r-out co"><span class="r-pr">#></span> 487: 93.7321 -6.0625 -0.1549 2.2054 -0.9814 4.2105 3.9949 0.3870 0.2993 0.1864 5.4712 1.6634</span> +<span class="r-out co"><span class="r-pr">#></span> 488: 93.7326 -6.0623 -0.1550 2.2054 -0.9814 4.2104 3.9935 0.3868 0.2996 0.1865 5.4721 1.6635</span> +<span class="r-out co"><span class="r-pr">#></span> 489: 93.7342 -6.0615 -0.1551 2.2054 -0.9815 4.2103 3.9893 0.3866 0.2998 0.1866 5.4725 1.6635</span> +<span class="r-out co"><span class="r-pr">#></span> 490: 93.7360 -6.0610 -0.1551 2.2053 -0.9815 4.2116 3.9857 0.3864 0.3001 0.1867 5.4730 1.6636</span> +<span class="r-out co"><span class="r-pr">#></span> 491: 93.7374 -6.0601 -0.1551 2.2052 -0.9815 4.2128 3.9804 0.3862 0.3003 0.1868 5.4722 1.6638</span> +<span class="r-out co"><span class="r-pr">#></span> 492: 93.7386 -6.0597 -0.1552 2.2050 -0.9816 4.2171 3.9774 0.3861 0.3006 0.1869 5.4714 1.6642</span> +<span class="r-out co"><span class="r-pr">#></span> 493: 93.7399 -6.0597 -0.1553 2.2049 -0.9816 4.2262 3.9766 0.3859 0.3008 0.1869 5.4712 1.6643</span> +<span class="r-out co"><span class="r-pr">#></span> 494: 93.7404 -6.0596 -0.1553 2.2047 -0.9816 4.2347 3.9746 0.3857 0.3011 0.1870 5.4711 1.6646</span> +<span class="r-out co"><span class="r-pr">#></span> 495: 93.7406 -6.0590 -0.1554 2.2046 -0.9817 4.2395 3.9711 0.3855 0.3014 0.1871 5.4705 1.6650</span> +<span class="r-out co"><span class="r-pr">#></span> 496: 93.7416 -6.0582 -0.1554 2.2045 -0.9817 4.2456 3.9660 0.3853 0.3017 0.1871 5.4707 1.6656</span> +<span class="r-out co"><span class="r-pr">#></span> 497: 93.7433 -6.0575 -0.1555 2.2044 -0.9818 4.2511 3.9631 0.3851 0.3020 0.1871 5.4714 1.6658</span> +<span class="r-out co"><span class="r-pr">#></span> 498: 93.7444 -6.0574 -0.1556 2.2042 -0.9817 4.2516 3.9632 0.3848 0.3023 0.1871 5.4721 1.6660</span> +<span class="r-out co"><span class="r-pr">#></span> 499: 93.7457 -6.0576 -0.1557 2.2041 -0.9817 4.2518 3.9660 0.3846 0.3025 0.1871 5.4728 1.6660</span> +<span class="r-out co"><span class="r-pr">#></span> 500: 93.7469 -6.0586 -0.1557 2.2040 -0.9817 4.2481 3.9757 0.3844 0.3028 0.1871 5.4738 1.6661</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-in"><span class="va">f_nlmixr_fomc_sfo_focei_obs</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_obs</span><span class="op">[</span><span class="st">"FOMC-SFO"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"focei"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="font-weight: bold;">Key:</span> U: Unscaled Parameters; X: Back-transformed parameters; G: Gill difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> F: Forward difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> C: Central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> M: Mixed forward and central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> Unscaled parameters for Omegas=chol(solve(omega));</span> +<span class="r-out co"><span class="r-pr">#></span> Diagonals are transformed, as specified by foceiControl(diagXform=)</span> +<span class="r-out co"><span class="r-pr">#></span> |-----+---------------+-----------+-----------+-----------+-----------|</span> +<span class="r-out co"><span class="r-pr">#></span> | #| Objective Fun | parent_0 | log_k_A1 |f_parent_qlogis | log_alpha |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| log_beta |sigma_parent | sigma_A1 | o1 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| o2 | o3 | o4 | o5 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 1</span>| 468.02617 | 1.000 | -1.000 | -0.9113 | -0.8954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8491 | -0.8511 | -0.8672 | -0.8762 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8737 | -0.8674 | -0.8694 | -0.8687 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.02617 | 94.00 | -5.400 | -0.9900 | -0.2000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 2.000 | 1.200 | 0.7536 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8758 | 1.189 | 1.093 | 1.127 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.02617</span> | 94.00 | 0.004517 | 0.2709 | 0.8187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.166 | 2.000 | 1.200 | 0.7536 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8758 | 1.189 | 1.093 | 1.127 |</span> +<span class="r-out co"><span class="r-pr">#></span> | G| Gill Diff. | 49.30 | 2.016 | -0.2473 | -0.3737 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.227 | -27.89 | -10.29 | 8.753 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 11.17 | -12.52 | -9.819 | -8.910 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 2</span>| 4021.4865 | 0.2059 | -1.032 | -0.9073 | -0.8894 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8293 | -0.4019 | -0.7014 | -1.017 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.054 | -0.6658 | -0.7112 | -0.7251 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 4021.4865 | 19.35 | -5.432 | -0.9861 | -0.1940 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.120 | 2.449 | 1.299 | 0.6474 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7182 | 1.429 | 1.266 | 1.289 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 4021.4865</span> | 19.35 | 0.004372 | 0.2717 | 0.8237 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.329 | 2.449 | 1.299 | 0.6474 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7182 | 1.429 | 1.266 | 1.289 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 3</span>| 518.20369 | 0.9206 | -1.003 | -0.9109 | -0.8948 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8471 | -0.8062 | -0.8506 | -0.8903 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8917 | -0.8473 | -0.8535 | -0.8543 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 518.20369 | 86.53 | -5.403 | -0.9896 | -0.1994 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 2.045 | 1.210 | 0.7430 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8600 | 1.213 | 1.111 | 1.143 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 518.20369</span> | 86.53 | 0.004502 | 0.2710 | 0.8192 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.182 | 2.045 | 1.210 | 0.7430 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8600 | 1.213 | 1.111 | 1.143 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 4</span>| 467.99742 | 0.9921 | -1.000 | -0.9112 | -0.8953 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8489 | -0.8466 | -0.8655 | -0.8776 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8755 | -0.8654 | -0.8678 | -0.8672 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.99742 | 93.25 | -5.400 | -0.9900 | -0.1999 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 2.004 | 1.201 | 0.7526 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8742 | 1.192 | 1.095 | 1.129 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.99742</span> | 93.25 | 0.004515 | 0.2709 | 0.8188 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.168 | 2.004 | 1.201 | 0.7526 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8742 | 1.192 | 1.095 | 1.129 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -98.28 | 1.929 | -0.4044 | -0.4503 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.484 | -29.27 | -9.987 | 8.922 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.417 | -11.79 | -9.521 | -8.343 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 5</span>| 467.67344 | 0.9967 | -1.000 | -0.9112 | -0.8953 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8488 | -0.8452 | -0.8651 | -0.8780 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8760 | -0.8648 | -0.8673 | -0.8668 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.67344 | 93.69 | -5.400 | -0.9899 | -0.1999 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 2.006 | 1.201 | 0.7523 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8738 | 1.192 | 1.095 | 1.129 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.67344</span> | 93.69 | 0.004515 | 0.2709 | 0.8188 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.168 | 2.006 | 1.201 | 0.7523 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8738 | 1.192 | 1.095 | 1.129 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -11.92 | 1.963 | -0.3242 | -0.4184 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.350 | -28.16 | -10.02 | 8.541 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.305 | -11.80 | -9.512 | -8.408 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 6</span>| 467.50396 | 0.9983 | -1.001 | -0.9112 | -0.8952 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8487 | -0.8416 | -0.8638 | -0.8791 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8771 | -0.8633 | -0.8661 | -0.8658 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.50396 | 93.84 | -5.401 | -0.9899 | -0.1999 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.100 | 2.010 | 1.202 | 0.7514 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8729 | 1.194 | 1.097 | 1.130 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.50396</span> | 93.84 | 0.004514 | 0.2709 | 0.8188 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.170 | 2.010 | 1.202 | 0.7514 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8729 | 1.194 | 1.097 | 1.130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 7</span>| 467.27231 | 1.003 | -1.001 | -0.9110 | -0.8951 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8481 | -0.8306 | -0.8599 | -0.8825 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8803 | -0.8587 | -0.8624 | -0.8625 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.27231 | 94.27 | -5.401 | -0.9898 | -0.1997 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.101 | 2.021 | 1.204 | 0.7489 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8700 | 1.200 | 1.101 | 1.134 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.27231</span> | 94.27 | 0.004510 | 0.2710 | 0.8190 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.174 | 2.021 | 1.204 | 0.7489 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8700 | 1.200 | 1.101 | 1.134 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 101.6 | 1.991 | -0.1997 | -0.3688 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.177 | -25.72 | -9.853 | 9.249 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.335 | -11.58 | -9.288 | -8.277 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 8</span>| 466.36087 | 0.9961 | -1.002 | -0.9109 | -0.8949 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8474 | -0.8165 | -0.8547 | -0.8873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8853 | -0.8526 | -0.8575 | -0.8582 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.36087 | 93.63 | -5.402 | -0.9896 | -0.1995 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 2.035 | 1.207 | 0.7453 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8657 | 1.207 | 1.106 | 1.139 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.36087</span> | 93.63 | 0.004506 | 0.2710 | 0.8191 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.180 | 2.035 | 1.207 | 0.7453 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8657 | 1.207 | 1.106 | 1.139 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -21.78 | 1.909 | -0.3215 | -0.4291 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.401 | -25.38 | -9.315 | 7.655 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 10.17 | -11.26 | -9.035 | -7.894 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 9</span>| 465.79764 | 1.000 | -1.004 | -0.9107 | -0.8946 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8467 | -0.8024 | -0.8495 | -0.8920 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8917 | -0.8462 | -0.8524 | -0.8537 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 465.79764 | 94.04 | -5.404 | -0.9895 | -0.1993 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.102 | 2.049 | 1.211 | 0.7417 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8600 | 1.214 | 1.112 | 1.144 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 465.79764</span> | 94.04 | 0.004501 | 0.2710 | 0.8193 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.186 | 2.049 | 1.211 | 0.7417 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8600 | 1.214 | 1.112 | 1.144 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 54.81 | 1.910 | -0.2489 | -0.4009 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.285 | -22.17 | -8.389 | 8.020 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 7.340 | -11.02 | -8.786 | -7.720 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 10</span>| 465.18897 | 0.9945 | -1.005 | -0.9105 | -0.8943 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8457 | -0.7893 | -0.8445 | -0.8971 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8975 | -0.8390 | -0.8467 | -0.8487 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 465.18897 | 93.48 | -5.405 | -0.9893 | -0.1990 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.103 | 2.062 | 1.214 | 0.7379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8549 | 1.223 | 1.118 | 1.149 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 465.18897</span> | 93.48 | 0.004495 | 0.2711 | 0.8196 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.194 | 2.062 | 1.214 | 0.7379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8549 | 1.223 | 1.118 | 1.149 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -47.52 | 1.834 | -0.3684 | -0.4503 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.489 | -22.39 | -7.996 | 7.294 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.249 | -10.90 | -8.741 | -7.575 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 11</span>| 464.56229 | 0.9983 | -1.006 | -0.9102 | -0.8940 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8445 | -0.7772 | -0.8401 | -0.9030 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9029 | -0.8305 | -0.8400 | -0.8430 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 464.56229 | 93.84 | -5.406 | -0.9890 | -0.1986 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.105 | 2.074 | 1.216 | 0.7334 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8503 | 1.233 | 1.125 | 1.156 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 464.56229</span> | 93.84 | 0.004488 | 0.2711 | 0.8199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.204 | 2.074 | 1.216 | 0.7334 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8503 | 1.233 | 1.125 | 1.156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 12</span>| 463.71730 | 0.9982 | -1.009 | -0.9098 | -0.8933 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8424 | -0.7583 | -0.8332 | -0.9128 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9112 | -0.8167 | -0.8291 | -0.8337 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 463.7173 | 93.83 | -5.409 | -0.9885 | -0.1980 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.107 | 2.093 | 1.220 | 0.7260 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8430 | 1.249 | 1.137 | 1.166 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 463.7173</span> | 93.83 | 0.004478 | 0.2712 | 0.8204 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.221 | 2.093 | 1.220 | 0.7260 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8430 | 1.249 | 1.137 | 1.166 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 13</span>| 461.03699 | 0.9978 | -1.018 | -0.9080 | -0.8909 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8343 | -0.6839 | -0.8059 | -0.9516 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9441 | -0.7622 | -0.7862 | -0.7969 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 461.03699 | 93.79 | -5.418 | -0.9868 | -0.1955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.115 | 2.167 | 1.237 | 0.6968 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8141 | 1.314 | 1.184 | 1.208 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 461.03699</span> | 93.79 | 0.004435 | 0.2716 | 0.8224 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.288 | 2.167 | 1.237 | 0.6968 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8141 | 1.314 | 1.184 | 1.208 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 14</span>| 458.83693 | 0.9972 | -1.033 | -0.9052 | -0.8871 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8218 | -0.5692 | -0.7639 | -1.011 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9948 | -0.6782 | -0.7201 | -0.7403 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.83693 | 93.74 | -5.433 | -0.9840 | -0.1917 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.127 | 2.282 | 1.262 | 0.6519 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7697 | 1.414 | 1.256 | 1.272 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.83693</span> | 93.74 | 0.004371 | 0.2721 | 0.8255 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.393 | 2.282 | 1.262 | 0.6519 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7697 | 1.414 | 1.256 | 1.272 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 0.05416 | 1.397 | -0.2200 | -0.5344 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.585 | -3.387 | -1.306 | -0.2250 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.392 | -3.452 | -2.065 | -1.405 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 15</span>| 459.30045 | 0.9957 | -1.166 | -0.8845 | -0.8313 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6584 | -0.5528 | -0.7505 | -0.8569 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.017 | -0.4560 | -0.6245 | -0.7036 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 459.30045 | 93.60 | -5.566 | -0.9635 | -0.1360 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.291 | 2.298 | 1.270 | 0.7682 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7505 | 1.678 | 1.361 | 1.313 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 459.30045</span> | 93.60 | 0.003827 | 0.2762 | 0.8729 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.881 | 2.298 | 1.270 | 0.7682 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7505 | 1.678 | 1.361 | 1.313 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 16</span>| 458.36319 | 0.9960 | -1.071 | -0.8992 | -0.8719 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7770 | -0.5045 | -0.7383 | -0.9927 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.023 | -0.5931 | -0.6727 | -0.7107 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.36319 | 93.63 | -5.471 | -0.9780 | -0.1766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.172 | 2.347 | 1.277 | 0.6658 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7452 | 1.515 | 1.308 | 1.305 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.36319</span> | 93.63 | 0.004206 | 0.2733 | 0.8381 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.777 | 2.347 | 1.277 | 0.6658 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7452 | 1.515 | 1.308 | 1.305 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -12.30 | 1.214 | 0.06343 | -0.2616 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6069 | 0.08029 | 0.4273 | 0.07297 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3937 | 0.3470 | 0.5201 | 0.09241 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 17</span>| 458.37724 | 0.9977 | -1.183 | -0.9046 | -0.8476 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7196 | -0.4765 | -0.7567 | -1.014 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9850 | -0.5955 | -0.6985 | -0.7030 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.37724 | 93.79 | -5.583 | -0.9834 | -0.1522 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.229 | 2.375 | 1.266 | 0.6497 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7783 | 1.513 | 1.280 | 1.314 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.37724</span> | 93.79 | 0.003762 | 0.2722 | 0.8588 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.295 | 2.375 | 1.266 | 0.6497 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7783 | 1.513 | 1.280 | 1.314 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 18</span>| 458.32800 | 0.9976 | -1.124 | -0.9017 | -0.8605 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7499 | -0.4913 | -0.7470 | -1.003 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.005 | -0.5943 | -0.6849 | -0.7071 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.328 | 93.78 | -5.524 | -0.9806 | -0.1651 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.199 | 2.360 | 1.272 | 0.6583 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7608 | 1.514 | 1.295 | 1.309 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.328</span> | 93.78 | 0.003990 | 0.2728 | 0.8478 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.017 | 2.360 | 1.272 | 0.6583 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7608 | 1.514 | 1.295 | 1.309 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 9.757 | 1.093 | -0.06310 | 0.02237 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.09811 | 0.3115 | -0.3381 | -0.2098 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8196 | 0.7052 | 0.04425 | 0.2610 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 19</span>| 458.25889 | 0.9968 | -1.183 | -0.9011 | -0.8543 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7363 | -0.4871 | -0.7422 | -1.003 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.023 | -0.6115 | -0.6911 | -0.7106 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.25889 | 93.70 | -5.583 | -0.9799 | -0.1589 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.213 | 2.364 | 1.275 | 0.6583 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7450 | 1.494 | 1.288 | 1.305 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.25889</span> | 93.70 | 0.003760 | 0.2729 | 0.8531 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.141 | 2.364 | 1.275 | 0.6583 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7450 | 1.494 | 1.288 | 1.305 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.6125 | 0.8824 | -0.01905 | 0.1697 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4368 | 0.4743 | 0.05191 | -0.6440 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4868 | -0.9136 | -0.3225 | -0.06220 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 20</span>| 458.18570 | 0.9978 | -1.246 | -0.9006 | -0.8585 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7495 | -0.4978 | -0.7385 | -0.9895 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.024 | -0.6046 | -0.6874 | -0.7124 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.1857 | 93.79 | -5.646 | -0.9794 | -0.1632 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.200 | 2.353 | 1.277 | 0.6683 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7440 | 1.502 | 1.292 | 1.303 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.1857</span> | 93.79 | 0.003532 | 0.2730 | 0.8495 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.022 | 2.353 | 1.277 | 0.6683 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7440 | 1.502 | 1.292 | 1.303 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 21</span>| 458.13464 | 0.9963 | -1.435 | -0.8992 | -0.8705 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7875 | -0.5278 | -0.7264 | -0.9531 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.031 | -0.5901 | -0.6784 | -0.7184 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.13464 | 93.65 | -5.835 | -0.9781 | -0.1751 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.162 | 2.323 | 1.284 | 0.6957 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7378 | 1.519 | 1.302 | 1.296 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.13464</span> | 93.65 | 0.002922 | 0.2733 | 0.8394 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.685 | 2.323 | 1.284 | 0.6957 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7378 | 1.519 | 1.302 | 1.296 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -15.15 | 0.2290 | 0.2476 | -0.1455 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7111 | -1.138 | 0.8895 | 1.880 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.837 | 0.2029 | 0.3485 | -0.6531 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 22</span>| 458.67841 | 0.9992 | -1.651 | -0.9027 | -0.9245 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8733 | -0.5209 | -0.7232 | -1.036 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.001 | -0.6164 | -0.6125 | -0.6771 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.67841 | 93.92 | -6.051 | -0.9815 | -0.2291 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.076 | 2.330 | 1.286 | 0.6333 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7647 | 1.488 | 1.374 | 1.343 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.67841</span> | 93.92 | 0.002355 | 0.2726 | 0.7952 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 7.971 | 2.330 | 1.286 | 0.6333 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7647 | 1.488 | 1.374 | 1.343 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 23</span>| 458.25487 | 1.002 | -1.469 | -0.8998 | -0.8789 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8006 | -0.5263 | -0.7262 | -0.9666 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5942 | -0.6683 | -0.7117 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.25487 | 94.17 | -5.869 | -0.9787 | -0.1835 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.148 | 2.325 | 1.285 | 0.6855 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7425 | 1.514 | 1.313 | 1.304 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.25487</span> | 94.17 | 0.002825 | 0.2732 | 0.8324 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.572 | 2.325 | 1.285 | 0.6855 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7425 | 1.514 | 1.313 | 1.304 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 24</span>| 458.28425 | 1.002 | -1.442 | -0.8994 | -0.8721 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7899 | -0.5271 | -0.7267 | -0.9564 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.030 | -0.5910 | -0.6765 | -0.7168 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.28425 | 94.21 | -5.842 | -0.9783 | -0.1768 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.159 | 2.324 | 1.284 | 0.6932 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7392 | 1.518 | 1.304 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.28425</span> | 94.21 | 0.002902 | 0.2732 | 0.8380 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.664 | 2.324 | 1.284 | 0.6932 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7392 | 1.518 | 1.304 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 25</span>| 458.13208 | 0.9983 | -1.435 | -0.8993 | -0.8705 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7874 | -0.5276 | -0.7266 | -0.9533 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.031 | -0.5901 | -0.6785 | -0.7183 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.13208 | 93.84 | -5.835 | -0.9781 | -0.1751 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.162 | 2.323 | 1.284 | 0.6955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7380 | 1.519 | 1.302 | 1.296 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.13208</span> | 93.84 | 0.002922 | 0.2733 | 0.8394 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.686 | 2.323 | 1.284 | 0.6955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7380 | 1.519 | 1.302 | 1.296 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 13.75 | 0.2391 | 0.3431 | -0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6079 | -1.684 | 0.2301 | 1.587 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9924 | -0.4675 | 0.3927 | -0.7567 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 26</span>| 458.12484 | 0.9973 | -1.435 | -0.8993 | -0.8705 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7874 | -0.5275 | -0.7266 | -0.9535 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.031 | -0.5900 | -0.6785 | -0.7182 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.12484 | 93.75 | -5.835 | -0.9782 | -0.1751 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.162 | 2.324 | 1.284 | 0.6954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7379 | 1.519 | 1.302 | 1.297 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.12484</span> | 93.75 | 0.002922 | 0.2733 | 0.8394 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.686 | 2.324 | 1.284 | 0.6954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7379 | 1.519 | 1.302 | 1.297 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.4576 | 0.2336 | 0.2904 | -0.1274 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6585 | -1.014 | 0.9040 | 1.932 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.695 | 0.2950 | 0.3980 | -0.7211 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 27</span>| 458.12349 | 0.9975 | -1.436 | -0.8994 | -0.8704 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7872 | -0.5272 | -0.7269 | -0.9542 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.031 | -0.5901 | -0.6787 | -0.7180 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.12349 | 93.76 | -5.836 | -0.9783 | -0.1751 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.162 | 2.324 | 1.284 | 0.6949 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7384 | 1.519 | 1.302 | 1.297 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.12349</span> | 93.76 | 0.002922 | 0.2732 | 0.8394 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.688 | 2.324 | 1.284 | 0.6949 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7384 | 1.519 | 1.302 | 1.297 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.734 | 0.2328 | 0.2907 | -0.1244 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6480 | -0.5259 | 1.203 | 2.086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.687 | 0.2714 | 0.3976 | -0.7167 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 28</span>| 458.12069 | 0.9972 | -1.436 | -0.8995 | -0.8704 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7868 | -0.5270 | -0.7278 | -0.9557 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.030 | -0.5902 | -0.6785 | -0.7174 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.12069 | 93.74 | -5.836 | -0.9784 | -0.1750 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.162 | 2.324 | 1.284 | 0.6937 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7392 | 1.519 | 1.302 | 1.297 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.12069</span> | 93.74 | 0.002921 | 0.2732 | 0.8394 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.691 | 2.324 | 1.284 | 0.6937 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7392 | 1.519 | 1.302 | 1.297 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.995 | 0.2265 | 0.2648 | -0.1319 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6577 | -1.056 | 0.5532 | 1.629 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4851 | 0.2582 | 0.3806 | -0.6784 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 29</span>| 458.12793 | 0.9986 | -1.436 | -0.8997 | -0.8703 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7863 | -0.5263 | -0.7282 | -0.9568 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.029 | -0.5904 | -0.6788 | -0.7169 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.12793 | 93.87 | -5.836 | -0.9785 | -0.1749 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.163 | 2.325 | 1.283 | 0.6929 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7395 | 1.519 | 1.302 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.12793</span> | 93.87 | 0.002920 | 0.2732 | 0.8395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.695 | 2.325 | 1.283 | 0.6929 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7395 | 1.519 | 1.302 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 30</span>| 458.12002 | 0.9975 | -1.436 | -0.8996 | -0.8704 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7866 | -0.5269 | -0.7279 | -0.9559 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.030 | -0.5903 | -0.6786 | -0.7173 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.12002 | 93.77 | -5.836 | -0.9784 | -0.1750 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.162 | 2.324 | 1.284 | 0.6935 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7392 | 1.519 | 1.302 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.12002</span> | 93.77 | 0.002921 | 0.2732 | 0.8395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.692 | 2.324 | 1.284 | 0.6935 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7392 | 1.519 | 1.302 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.647 | 0.2293 | 0.2815 | -0.1267 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6372 | -0.9129 | 0.8290 | 1.823 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.624 | 0.2659 | 0.4184 | -0.6478 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 31</span>| 458.11922 | 0.9973 | -1.436 | -0.8996 | -0.8704 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7866 | -0.5268 | -0.7280 | -0.9563 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.029 | -0.5903 | -0.6786 | -0.7171 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.11922 | 93.74 | -5.836 | -0.9784 | -0.1750 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.163 | 2.324 | 1.284 | 0.6933 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7394 | 1.519 | 1.302 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.11922</span> | 93.74 | 0.002920 | 0.2732 | 0.8395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.693 | 2.324 | 1.284 | 0.6933 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7394 | 1.519 | 1.302 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.8024 | 0.2274 | 0.2665 | -0.1307 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6475 | -1.019 | 0.5594 | 1.618 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.681 | 0.3232 | 0.3907 | -0.6658 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 32</span>| 458.11869 | 0.9974 | -1.436 | -0.8996 | -0.8703 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7864 | -0.5266 | -0.7281 | -0.9565 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.029 | -0.5904 | -0.6787 | -0.7170 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.11869 | 93.76 | -5.836 | -0.9785 | -0.1750 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.163 | 2.324 | 1.283 | 0.6931 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7397 | 1.519 | 1.302 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.11869</span> | 93.76 | 0.002920 | 0.2732 | 0.8395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.694 | 2.324 | 1.283 | 0.6931 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7397 | 1.519 | 1.302 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.112 | 0.2271 | 0.2694 | -0.1286 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6401 | -1.529 | 0.3516 | 1.832 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3653 | 0.2635 | 0.3774 | -0.6589 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 33</span>| 458.11797 | 0.9972 | -1.436 | -0.8997 | -0.8703 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7863 | -0.5263 | -0.7282 | -0.9569 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.029 | -0.5904 | -0.6788 | -0.7169 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.11797 | 93.74 | -5.836 | -0.9785 | -0.1749 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.163 | 2.325 | 1.283 | 0.6928 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7397 | 1.519 | 1.302 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.11797</span> | 93.74 | 0.002920 | 0.2732 | 0.8395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.695 | 2.325 | 1.283 | 0.6928 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7397 | 1.519 | 1.302 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.528 | 0.2260 | 0.2581 | -0.1311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6478 | -1.074 | 0.7096 | 1.705 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.609 | 0.2690 | 0.3809 | -0.6419 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 34</span>| 458.11744 | 0.9975 | -1.436 | -0.8997 | -0.8703 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7862 | -0.5262 | -0.7283 | -0.9571 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.029 | -0.5904 | -0.6788 | -0.7168 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.11744 | 93.76 | -5.836 | -0.9786 | -0.1749 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.163 | 2.325 | 1.283 | 0.6926 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7399 | 1.519 | 1.302 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.11744</span> | 93.76 | 0.002920 | 0.2732 | 0.8395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.696 | 2.325 | 1.283 | 0.6926 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7399 | 1.519 | 1.302 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.737 | 0.2262 | 0.2659 | -0.1276 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6346 | -0.9458 | 0.5100 | 1.567 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.640 | 0.3111 | 0.3526 | -0.6225 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 35</span>| 458.11714 | 0.9972 | -1.436 | -0.8998 | -0.8703 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7861 | -0.5260 | -0.7284 | -0.9574 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.029 | -0.5905 | -0.6789 | -0.7167 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.11714 | 93.74 | -5.836 | -0.9786 | -0.1749 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.163 | 2.325 | 1.283 | 0.6924 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7402 | 1.519 | 1.302 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.11714</span> | 93.74 | 0.002920 | 0.2732 | 0.8395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.697 | 2.325 | 1.283 | 0.6924 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7402 | 1.519 | 1.302 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.976 | 0.2241 | 0.2491 | -0.1309 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6467 | -0.8649 | 0.8521 | 1.757 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.585 | 0.2641 | 0.3618 | -0.6092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 36</span>| 458.11663 | 0.9975 | -1.436 | -0.8998 | -0.8703 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7860 | -0.5259 | -0.7285 | -0.9576 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.028 | -0.5905 | -0.6789 | -0.7166 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.11663 | 93.76 | -5.836 | -0.9787 | -0.1749 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.163 | 2.325 | 1.283 | 0.6923 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7404 | 1.518 | 1.301 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.11663</span> | 93.76 | 0.002920 | 0.2732 | 0.8396 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.698 | 2.325 | 1.283 | 0.6923 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7404 | 1.518 | 1.301 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.001 | 0.2249 | 0.2609 | -0.1271 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6310 | -0.8317 | 0.8110 | 1.745 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3162 | 0.2564 | 0.3586 | -0.6097 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 37</span>| 458.11610 | 0.9971 | -1.436 | -0.8999 | -0.8702 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7859 | -0.5258 | -0.7286 | -0.9579 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.028 | -0.5906 | -0.6790 | -0.7165 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.1161 | 93.73 | -5.836 | -0.9787 | -0.1749 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.163 | 2.325 | 1.283 | 0.6920 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7404 | 1.518 | 1.301 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.1161</span> | 93.73 | 0.002920 | 0.2732 | 0.8396 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.699 | 2.325 | 1.283 | 0.6920 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7404 | 1.518 | 1.301 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.471 | 0.2228 | 0.2417 | -0.1310 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6447 | -1.605 | 0.009434 | 1.531 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.615 | 0.2909 | 0.3664 | -0.6093 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 38</span>| 458.11531 | 0.9974 | -1.436 | -0.8999 | -0.8702 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7859 | -0.5256 | -0.7287 | -0.9582 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.028 | -0.5905 | -0.6791 | -0.7164 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.11531 | 93.76 | -5.836 | -0.9788 | -0.1749 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.163 | 2.326 | 1.283 | 0.6918 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7405 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.11531</span> | 93.76 | 0.002919 | 0.2731 | 0.8396 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.699 | 2.326 | 1.283 | 0.6918 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7405 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.540 | 0.2236 | 0.2522 | -0.1268 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6308 | -0.9638 | 0.7239 | 1.714 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.540 | 0.2567 | 0.3599 | -0.5942 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 39</span>| 458.11496 | 0.9972 | -1.436 | -0.8999 | -0.8702 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7858 | -0.5254 | -0.7288 | -0.9585 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.028 | -0.5906 | -0.6791 | -0.7163 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.11496 | 93.74 | -5.836 | -0.9788 | -0.1748 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.163 | 2.326 | 1.283 | 0.6916 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7408 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.11496</span> | 93.74 | 0.002919 | 0.2731 | 0.8396 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.700 | 2.326 | 1.283 | 0.6916 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7408 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.772 | 0.2217 | 0.2376 | -0.1305 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6412 | -1.736 | 0.1210 | 1.307 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.540 | 0.2780 | 0.3483 | -0.5916 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 40</span>| 458.11458 | 0.9975 | -1.436 | -0.9000 | -0.8702 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7857 | -0.5252 | -0.7289 | -0.9587 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.028 | -0.5906 | -0.6792 | -0.7163 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.11458 | 93.76 | -5.836 | -0.9788 | -0.1748 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.163 | 2.326 | 1.283 | 0.6915 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7410 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.11458</span> | 93.76 | 0.002919 | 0.2731 | 0.8396 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.701 | 2.326 | 1.283 | 0.6915 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7410 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.896 | 0.2223 | 0.2476 | -0.1262 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6268 | -0.4531 | 0.7600 | 1.698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.483 | 0.2984 | 0.3374 | -0.6006 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 41</span>| 458.11430 | 0.9972 | -1.436 | -0.9000 | -0.8702 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7856 | -0.5251 | -0.7290 | -0.9589 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.5907 | -0.6792 | -0.7162 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.1143 | 93.73 | -5.836 | -0.9789 | -0.1748 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.164 | 2.326 | 1.283 | 0.6913 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7412 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.1143</span> | 93.73 | 0.002919 | 0.2731 | 0.8396 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.702 | 2.326 | 1.283 | 0.6913 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7412 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.121 | 0.2201 | 0.2306 | -0.1307 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6392 | -0.8820 | 0.4853 | 1.475 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.568 | 0.2856 | 0.3442 | -0.5942 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 42</span>| 458.11392 | 0.9975 | -1.437 | -0.9001 | -0.8702 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7855 | -0.5250 | -0.7290 | -0.9592 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.5907 | -0.6793 | -0.7161 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.11392 | 93.76 | -5.837 | -0.9789 | -0.1748 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.164 | 2.326 | 1.283 | 0.6911 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7414 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.11392</span> | 93.76 | 0.002919 | 0.2731 | 0.8396 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.702 | 2.326 | 1.283 | 0.6911 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7414 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.218 | 0.2203 | 0.2415 | -0.1269 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6242 | -1.700 | -0.1298 | 1.090 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.097 | -0.4639 | 0.3406 | -0.5940 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 43</span>| 458.11292 | 0.9972 | -1.437 | -0.9001 | -0.8702 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7854 | -0.5247 | -0.7291 | -0.9594 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.5906 | -0.6794 | -0.7160 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.11292 | 93.74 | -5.837 | -0.9790 | -0.1748 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.164 | 2.326 | 1.283 | 0.6909 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7412 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.11292</span> | 93.74 | 0.002919 | 0.2731 | 0.8396 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.703 | 2.326 | 1.283 | 0.6909 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7412 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.114 | 0.2202 | 0.2288 | -0.1307 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6328 | -0.7727 | 0.7964 | 1.664 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2569 | 0.2827 | 0.3132 | -0.5835 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 44</span>| 458.11219 | 0.9975 | -1.437 | -0.9002 | -0.8701 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7853 | -0.5246 | -0.7293 | -0.9597 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.5907 | -0.6795 | -0.7158 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.11219 | 93.76 | -5.837 | -0.9790 | -0.1748 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.164 | 2.327 | 1.283 | 0.6907 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7413 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.11219</span> | 93.76 | 0.002919 | 0.2731 | 0.8397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.704 | 2.327 | 1.283 | 0.6907 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7413 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.924 | 0.2207 | 0.2357 | -0.1254 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6202 | -0.4451 | 0.8288 | 1.643 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.561 | 0.2786 | 0.3167 | -0.5797 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 45</span>| 458.11161 | 0.9972 | -1.437 | -0.9002 | -0.8701 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7852 | -0.5246 | -0.7295 | -0.9601 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.5907 | -0.6795 | -0.7157 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.11161 | 93.74 | -5.837 | -0.9791 | -0.1747 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.164 | 2.327 | 1.283 | 0.6904 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7414 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.11161</span> | 93.74 | 0.002918 | 0.2731 | 0.8397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.705 | 2.327 | 1.283 | 0.6904 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7414 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.221 | 0.2188 | 0.2217 | -0.1291 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6301 | -1.629 | 0.1332 | 1.223 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.491 | 0.2969 | 0.3215 | -0.5516 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 46</span>| 458.11130 | 0.9974 | -1.437 | -0.9003 | -0.8701 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7851 | -0.5243 | -0.7295 | -0.9603 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.5907 | -0.6796 | -0.7156 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.1113 | 93.76 | -5.837 | -0.9791 | -0.1747 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.164 | 2.327 | 1.283 | 0.6902 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7416 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.1113</span> | 93.76 | 0.002918 | 0.2731 | 0.8397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.706 | 2.327 | 1.283 | 0.6902 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7416 | 1.518 | 1.301 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.605 | 0.2188 | 0.2279 | -0.1262 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6191 | -1.596 | 0.1216 | 1.254 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.158 | -0.4084 | 0.3005 | -0.5648 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 47</span>| 458.11059 | 0.9972 | -1.437 | -0.9003 | -0.8701 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7850 | -0.5240 | -0.7295 | -0.9605 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.5906 | -0.6796 | -0.7155 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.11059 | 93.73 | -5.837 | -0.9791 | -0.1747 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.164 | 2.327 | 1.283 | 0.6901 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7415 | 1.518 | 1.301 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.11059</span> | 93.73 | 0.002918 | 0.2731 | 0.8397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.707 | 2.327 | 1.283 | 0.6901 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7415 | 1.518 | 1.301 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.022 | 0.2179 | 0.2140 | -0.1317 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6294 | -0.4112 | 0.8588 | 1.629 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.524 | 0.3410 | 0.3226 | -0.5400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 48</span>| 458.10995 | 0.9975 | -1.437 | -0.9003 | -0.8701 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7849 | -0.5239 | -0.7297 | -0.9608 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.5906 | -0.6797 | -0.7154 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10995 | 93.76 | -5.837 | -0.9792 | -0.1747 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.164 | 2.327 | 1.283 | 0.6899 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7416 | 1.518 | 1.301 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10995</span> | 93.76 | 0.002918 | 0.2731 | 0.8397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.708 | 2.327 | 1.283 | 0.6899 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7416 | 1.518 | 1.301 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.872 | 0.2188 | 0.2245 | -0.1278 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6141 | -1.055 | 0.5121 | 1.433 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.504 | 0.3641 | 0.3235 | -0.5302 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 49</span>| 458.10978 | 0.9972 | -1.437 | -0.9004 | -0.8700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7848 | -0.5238 | -0.7297 | -0.9610 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.5907 | -0.6797 | -0.7153 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10978 | 93.73 | -5.837 | -0.9792 | -0.1747 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.164 | 2.327 | 1.282 | 0.6897 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7418 | 1.518 | 1.301 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10978</span> | 93.73 | 0.002918 | 0.2730 | 0.8397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.709 | 2.327 | 1.282 | 0.6897 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7418 | 1.518 | 1.301 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -2.410 | 0.2142 | 0.1743 | -0.1457 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6441 | -0.7806 | 0.7426 | 1.188 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06181 | -0.3659 | 0.5158 | -0.5913 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 50</span>| 458.10914 | 0.9975 | -1.437 | -0.9004 | -0.8700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7847 | -0.5236 | -0.7299 | -0.9612 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.5906 | -0.6798 | -0.7152 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10914 | 93.77 | -5.837 | -0.9792 | -0.1747 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.164 | 2.327 | 1.282 | 0.6895 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7418 | 1.518 | 1.300 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10914</span> | 93.77 | 0.002918 | 0.2730 | 0.8397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.709 | 2.327 | 1.282 | 0.6895 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7418 | 1.518 | 1.300 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.690 | 0.2171 | 0.2203 | -0.1291 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6099 | -0.7940 | 0.4528 | 1.377 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.452 | 0.2831 | 0.2911 | -0.5300 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 51</span>| 458.10832 | 0.9972 | -1.437 | -0.9004 | -0.8700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7846 | -0.5235 | -0.7300 | -0.9615 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.5905 | -0.6799 | -0.7151 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10832 | 93.74 | -5.837 | -0.9793 | -0.1747 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.164 | 2.328 | 1.282 | 0.6893 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7418 | 1.518 | 1.300 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10832</span> | 93.74 | 0.002918 | 0.2730 | 0.8397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.710 | 2.328 | 1.282 | 0.6893 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7418 | 1.518 | 1.300 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.386 | 0.2164 | 0.2066 | -0.1317 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6210 | -0.6390 | 0.8493 | 1.598 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.491 | 0.2964 | 0.2278 | -0.4988 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 52</span>| 458.10801 | 0.9974 | -1.437 | -0.9005 | -0.8700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7845 | -0.5234 | -0.7302 | -0.9618 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5906 | -0.6800 | -0.7150 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10801 | 93.76 | -5.837 | -0.9793 | -0.1746 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.165 | 2.328 | 1.282 | 0.6891 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.518 | 1.300 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10801</span> | 93.76 | 0.002918 | 0.2730 | 0.8398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.711 | 2.328 | 1.282 | 0.6891 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.518 | 1.300 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.854 | 0.2167 | 0.2150 | -0.1282 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6083 | -0.7461 | 0.7029 | 1.539 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1981 | 0.2733 | 0.2717 | -0.5257 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 53</span>| 458.10765 | 0.9971 | -1.437 | -0.9005 | -0.8700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7844 | -0.5232 | -0.7303 | -0.9621 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5906 | -0.6800 | -0.7149 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10765 | 93.73 | -5.837 | -0.9794 | -0.1746 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.165 | 2.328 | 1.282 | 0.6889 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.518 | 1.300 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10765</span> | 93.73 | 0.002917 | 0.2730 | 0.8398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.712 | 2.328 | 1.282 | 0.6889 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.518 | 1.300 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.678 | 0.2148 | 0.1964 | -0.1329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6222 | -0.7140 | 0.5004 | 1.353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2647 | 0.3470 | 0.3026 | -0.5041 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 54</span>| 458.10677 | 0.9974 | -1.437 | -0.9006 | -0.8700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7843 | -0.5231 | -0.7305 | -0.9624 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5907 | -0.6801 | -0.7148 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10677 | 93.76 | -5.837 | -0.9794 | -0.1746 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.165 | 2.328 | 1.282 | 0.6887 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.518 | 1.300 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10677</span> | 93.76 | 0.002917 | 0.2730 | 0.8398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.713 | 2.328 | 1.282 | 0.6887 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.518 | 1.300 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.911 | 0.2164 | 0.2105 | -0.1281 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6034 | -0.7920 | 0.6471 | 1.488 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2445 | 0.2110 | 0.2380 | -0.4469 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 55</span>| 458.10609 | 0.9972 | -1.437 | -0.9006 | -0.8700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7842 | -0.5230 | -0.7306 | -0.9627 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5907 | -0.6801 | -0.7147 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10609 | 93.74 | -5.837 | -0.9794 | -0.1746 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.165 | 2.328 | 1.282 | 0.6884 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.518 | 1.300 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10609</span> | 93.74 | 0.002917 | 0.2730 | 0.8398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.714 | 2.328 | 1.282 | 0.6884 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.518 | 1.300 | 1.300 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.589 | 0.2148 | 0.1951 | -0.1322 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6145 | -0.8575 | 0.5942 | 1.427 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.492 | 0.2699 | 0.1872 | -0.4796 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 56</span>| 458.10567 | 0.9974 | -1.437 | -0.9006 | -0.8699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7841 | -0.5228 | -0.7308 | -0.9630 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5907 | -0.6801 | -0.7146 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10567 | 93.76 | -5.837 | -0.9795 | -0.1746 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.165 | 2.328 | 1.282 | 0.6882 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7422 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10567</span> | 93.76 | 0.002917 | 0.2730 | 0.8398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.715 | 2.328 | 1.282 | 0.6882 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7422 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.760 | 0.2153 | 0.2043 | -0.1283 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6005 | -0.7529 | 0.6292 | 1.454 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2107 | 0.2534 | 0.2280 | -0.4318 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 57</span>| 458.10540 | 0.9971 | -1.437 | -0.9007 | -0.8699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7840 | -0.5227 | -0.7309 | -0.9633 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5907 | -0.6801 | -0.7146 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.1054 | 93.73 | -5.837 | -0.9795 | -0.1745 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.165 | 2.328 | 1.282 | 0.6880 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.1054</span> | 93.73 | 0.002917 | 0.2730 | 0.8398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.716 | 2.328 | 1.282 | 0.6880 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.789 | 0.2130 | 0.1850 | -0.1339 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6160 | -0.6903 | 0.7130 | 1.481 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1975 | 0.2824 | 0.2646 | -0.4868 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 58</span>| 458.10444 | 0.9974 | -1.437 | -0.9007 | -0.8699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7839 | -0.5226 | -0.7311 | -0.9636 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5907 | -0.6801 | -0.7145 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10444 | 93.76 | -5.837 | -0.9796 | -0.1745 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.165 | 2.329 | 1.282 | 0.6878 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10444</span> | 93.76 | 0.002916 | 0.2730 | 0.8398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.717 | 2.329 | 1.282 | 0.6878 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.285 | 0.2143 | 0.1972 | -0.1290 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5987 | -0.7355 | 0.6064 | 1.421 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.460 | 0.2526 | 0.2188 | -0.4206 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 59</span>| 458.10435 | 0.9972 | -1.437 | -0.9008 | -0.8699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7838 | -0.5224 | -0.7312 | -0.9638 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5908 | -0.6802 | -0.7144 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10435 | 93.73 | -5.837 | -0.9796 | -0.1745 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.165 | 2.329 | 1.282 | 0.6876 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7425 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10435</span> | 93.73 | 0.002916 | 0.2730 | 0.8399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.718 | 2.329 | 1.282 | 0.6876 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7425 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -2.184 | 0.2097 | 0.1486 | -0.1446 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6255 | -0.7028 | 0.6444 | 1.495 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.416 | 0.3010 | 0.4942 | -0.5303 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 60</span>| 458.10393 | 0.9975 | -1.438 | -0.9008 | -0.8699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7837 | -0.5223 | -0.7313 | -0.9641 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5908 | -0.6802 | -0.7143 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10393 | 93.76 | -5.838 | -0.9796 | -0.1745 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.165 | 2.329 | 1.282 | 0.6873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7426 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10393</span> | 93.76 | 0.002916 | 0.2730 | 0.8399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.718 | 2.329 | 1.282 | 0.6873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7426 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.045 | 0.2119 | 0.1940 | -0.1305 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5955 | -0.7252 | 0.6285 | 1.413 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2070 | 0.2194 | 0.2208 | -0.3980 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 61</span>| 458.10364 | 0.9971 | -1.438 | -0.9008 | -0.8699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7836 | -0.5222 | -0.7314 | -0.9644 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5908 | -0.6803 | -0.7142 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10364 | 93.73 | -5.838 | -0.9796 | -0.1745 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.166 | 2.329 | 1.281 | 0.6871 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7427 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10364</span> | 93.73 | 0.002916 | 0.2730 | 0.8399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.719 | 2.329 | 1.281 | 0.6871 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7427 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.727 | 0.2108 | 0.1771 | -0.1339 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6094 | -0.7304 | 0.6317 | 1.376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.443 | 0.2644 | 0.2580 | -0.4629 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 62</span>| 458.10286 | 0.9974 | -1.438 | -0.9008 | -0.8699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7835 | -0.5221 | -0.7316 | -0.9647 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5908 | -0.6803 | -0.7141 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10286 | 93.75 | -5.838 | -0.9796 | -0.1745 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.166 | 2.329 | 1.281 | 0.6869 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7427 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10286</span> | 93.75 | 0.002915 | 0.2730 | 0.8399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.720 | 2.329 | 1.281 | 0.6869 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7427 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.225 | 0.2118 | 0.1898 | -0.1294 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5932 | -0.6493 | 0.6517 | 1.411 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1402 | 0.3233 | 0.2428 | -0.3732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 63</span>| 458.10253 | 0.9971 | -1.438 | -0.9009 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7834 | -0.5219 | -0.7318 | -0.9650 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5909 | -0.6803 | -0.7141 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10253 | 93.73 | -5.838 | -0.9797 | -0.1745 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.166 | 2.329 | 1.281 | 0.6867 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7428 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10253</span> | 93.73 | 0.002915 | 0.2730 | 0.8399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.721 | 2.329 | 1.281 | 0.6867 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7428 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.449 | 0.2099 | 0.1736 | -0.1338 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6049 | -0.7015 | 0.6330 | 1.384 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1863 | 0.2615 | 0.2563 | -0.4532 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 64</span>| 458.10167 | 0.9974 | -1.438 | -0.9009 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7832 | -0.5218 | -0.7320 | -0.9653 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5909 | -0.6804 | -0.7140 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10167 | 93.76 | -5.838 | -0.9797 | -0.1744 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.166 | 2.329 | 1.281 | 0.6864 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7427 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10167</span> | 93.76 | 0.002915 | 0.2729 | 0.8399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.722 | 2.329 | 1.281 | 0.6864 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7427 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.422 | 0.2110 | 0.1849 | -0.1293 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5889 | -0.5964 | 0.6731 | 1.405 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1535 | 0.3114 | 0.2496 | -0.4521 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 65</span>| 458.10133 | 0.9971 | -1.438 | -0.9009 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7831 | -0.5217 | -0.7321 | -0.9657 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5909 | -0.6804 | -0.7139 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10133 | 93.73 | -5.838 | -0.9798 | -0.1744 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.166 | 2.329 | 1.281 | 0.6862 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7428 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10133</span> | 93.73 | 0.002915 | 0.2729 | 0.8400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.723 | 2.329 | 1.281 | 0.6862 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7428 | 1.518 | 1.300 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.461 | 0.2094 | 0.1688 | -0.1332 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6003 | -0.7109 | 0.5914 | 1.349 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.404 | 0.2951 | 0.2552 | -0.4331 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 66</span>| 458.10059 | 0.9974 | -1.438 | -0.9009 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7830 | -0.5215 | -0.7323 | -0.9660 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5909 | -0.6804 | -0.7138 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10059 | 93.75 | -5.838 | -0.9798 | -0.1744 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.166 | 2.330 | 1.281 | 0.6860 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7428 | 1.518 | 1.300 | 1.302 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10059</span> | 93.75 | 0.002915 | 0.2729 | 0.8400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.724 | 2.330 | 1.281 | 0.6860 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7428 | 1.518 | 1.300 | 1.302 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.228 | 0.2101 | 0.1802 | -0.1294 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5857 | -0.2287 | 0.9339 | 1.558 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.376 | 0.3488 | 0.2665 | -0.4324 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 67</span>| 458.10050 | 0.9972 | -1.438 | -0.9010 | -0.8697 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7829 | -0.5215 | -0.7325 | -0.9663 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.025 | -0.5910 | -0.6804 | -0.7137 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.1005 | 93.73 | -5.838 | -0.9798 | -0.1744 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.166 | 2.330 | 1.281 | 0.6857 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7430 | 1.518 | 1.300 | 1.302 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.1005</span> | 93.73 | 0.002915 | 0.2729 | 0.8400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.725 | 2.330 | 1.281 | 0.6857 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7430 | 1.518 | 1.300 | 1.302 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -2.045 | 0.2058 | 0.1327 | -0.1461 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6105 | -0.6040 | 0.6130 | 0.9518 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01902 | 0.3702 | 0.4676 | -0.4886 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 68</span>| 458.10013 | 0.9974 | -1.438 | -0.9010 | -0.8697 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7829 | -0.5214 | -0.7325 | -0.9664 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.025 | -0.5910 | -0.6805 | -0.7136 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10013 | 93.75 | -5.838 | -0.9798 | -0.1744 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.166 | 2.330 | 1.281 | 0.6857 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7430 | 1.518 | 1.300 | 1.302 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10013</span> | 93.75 | 0.002914 | 0.2729 | 0.8400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.725 | 2.330 | 1.281 | 0.6857 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7430 | 1.518 | 1.300 | 1.302 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 0.8557 | 0.2088 | 0.1747 | -0.1300 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5847 | -0.2393 | 0.9114 | 1.536 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.367 | 0.3016 | 0.2557 | -0.4123 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 69</span>| 458.10002 | 0.9973 | -1.438 | -0.9010 | -0.8697 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7828 | -0.5214 | -0.7326 | -0.9665 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.025 | -0.5911 | -0.6805 | -0.7136 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.10002 | 93.74 | -5.838 | -0.9798 | -0.1744 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.166 | 2.330 | 1.281 | 0.6856 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7432 | 1.518 | 1.300 | 1.302 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.10002</span> | 93.74 | 0.002914 | 0.2729 | 0.8400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.726 | 2.330 | 1.281 | 0.6856 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7432 | 1.518 | 1.300 | 1.302 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -0.5131 | 0.2058 | 0.1358 | -0.1441 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6029 | -0.6262 | 0.5998 | 1.158 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.373 | 0.3470 | 0.4566 | -0.4872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 70</span>| 458.09992 | 0.9973 | -1.438 | -0.9010 | -0.8697 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7827 | -0.5214 | -0.7327 | -0.9666 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.025 | -0.5911 | -0.6806 | -0.7135 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.09992 | 93.75 | -5.838 | -0.9799 | -0.1743 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.166 | 2.330 | 1.281 | 0.6855 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7433 | 1.518 | 1.300 | 1.302 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.09992</span> | 93.75 | 0.002914 | 0.2729 | 0.8400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.726 | 2.330 | 1.281 | 0.6855 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7433 | 1.518 | 1.300 | 1.302 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 0.2584 | 0.2056 | 0.1371 | -0.1438 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5991 | -0.6198 | 0.6082 | 0.9676 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.295 | 0.3221 | 0.4533 | -0.4750 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 71</span>| 458.09944 | 0.9973 | -1.438 | -0.9010 | -0.8697 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7827 | -0.5213 | -0.7328 | -0.9668 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.025 | -0.5911 | -0.6806 | -0.7135 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.09944 | 93.75 | -5.838 | -0.9799 | -0.1743 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.166 | 2.330 | 1.281 | 0.6854 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7431 | 1.518 | 1.300 | 1.302 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.09944</span> | 93.75 | 0.002914 | 0.2729 | 0.8400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.727 | 2.330 | 1.281 | 0.6854 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7431 | 1.518 | 1.300 | 1.302 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 72</span>| 458.09825 | 0.9974 | -1.438 | -0.9011 | -0.8697 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7824 | -0.5210 | -0.7332 | -0.9672 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.025 | -0.5911 | -0.6808 | -0.7131 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.09825 | 93.76 | -5.838 | -0.9799 | -0.1743 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.167 | 2.330 | 1.280 | 0.6851 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7430 | 1.518 | 1.299 | 1.302 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.09825</span> | 93.76 | 0.002914 | 0.2729 | 0.8401 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.729 | 2.330 | 1.280 | 0.6851 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7430 | 1.518 | 1.299 | 1.302 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 73</span>| 458.09793 | 0.9981 | -1.438 | -0.9013 | -0.8695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7815 | -0.5202 | -0.7349 | -0.9686 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5909 | -0.6812 | -0.7117 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.09793 | 93.82 | -5.838 | -0.9801 | -0.1741 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.168 | 2.331 | 1.279 | 0.6840 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7428 | 1.518 | 1.299 | 1.304 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.09793</span> | 93.82 | 0.002913 | 0.2729 | 0.8402 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.737 | 2.331 | 1.279 | 0.6840 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7428 | 1.518 | 1.299 | 1.304 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 10.76 | 0.2116 | 0.1923 | -0.1162 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5255 | -0.5796 | 0.3777 | 1.210 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.409 | 0.2855 | 0.1875 | -0.3085 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 74</span>| 458.08987 | 0.9971 | -1.438 | -0.9013 | -0.8695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7808 | -0.5187 | -0.7369 | -0.9692 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5907 | -0.6832 | -0.7095 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08987 | 93.72 | -5.838 | -0.9802 | -0.1741 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.168 | 2.332 | 1.278 | 0.6836 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7427 | 1.518 | 1.297 | 1.306 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08987</span> | 93.72 | 0.002914 | 0.2729 | 0.8402 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.743 | 2.332 | 1.278 | 0.6836 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7427 | 1.518 | 1.297 | 1.306 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.512 | 0.2078 | 0.1434 | -0.1372 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5667 | -0.8061 | 0.1467 | 1.033 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.202 | -0.4065 | 0.09417 | -0.1935 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 75</span>| 458.08564 | 0.9973 | -1.438 | -0.9016 | -0.8695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7801 | -0.5170 | -0.7384 | -0.9704 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5898 | -0.6859 | -0.7082 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08564 | 93.74 | -5.838 | -0.9804 | -0.1741 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.169 | 2.334 | 1.277 | 0.6827 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7424 | 1.519 | 1.294 | 1.308 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08564</span> | 93.74 | 0.002914 | 0.2728 | 0.8402 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.749 | 2.334 | 1.277 | 0.6827 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7424 | 1.519 | 1.294 | 1.308 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 76</span>| 458.08078 | 0.9972 | -1.438 | -0.9021 | -0.8695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7788 | -0.5136 | -0.7416 | -0.9727 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.5879 | -0.6916 | -0.7053 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08078 | 93.73 | -5.838 | -0.9809 | -0.1742 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.170 | 2.338 | 1.275 | 0.6809 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7420 | 1.522 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08078</span> | 93.73 | 0.002915 | 0.2727 | 0.8402 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.761 | 2.338 | 1.275 | 0.6809 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7420 | 1.522 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.8456 | 0.2109 | 0.1052 | -0.1453 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5381 | -0.2225 | -0.1274 | 0.8336 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2653 | 0.4698 | -0.4321 | 0.07917 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 77</span>| 458.08109 | 0.9983 | -1.445 | -0.9066 | -0.8702 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7727 | -0.5143 | -0.7362 | -0.9770 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.5885 | -0.6915 | -0.7058 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08109 | 93.84 | -5.845 | -0.9853 | -0.1748 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.176 | 2.337 | 1.279 | 0.6777 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7418 | 1.521 | 1.288 | 1.310 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08109</span> | 93.84 | 0.002894 | 0.2718 | 0.8396 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.815 | 2.337 | 1.279 | 0.6777 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7418 | 1.521 | 1.288 | 1.310 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 78</span>| 458.08775 | 0.9985 | -1.441 | -0.9040 | -0.8696 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7757 | -0.5136 | -0.7393 | -0.9753 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5887 | -0.6911 | -0.7056 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08775 | 93.86 | -5.841 | -0.9828 | -0.1743 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.173 | 2.338 | 1.277 | 0.6789 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08775</span> | 93.86 | 0.002906 | 0.2723 | 0.8401 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.788 | 2.338 | 1.277 | 0.6789 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 79</span>| 458.08407 | 0.9980 | -1.438 | -0.9022 | -0.8694 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7783 | -0.5133 | -0.7415 | -0.9736 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5884 | -0.6912 | -0.7054 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08407 | 93.81 | -5.838 | -0.9810 | -0.1740 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6802 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7422 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08407</span> | 93.81 | 0.002915 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.766 | 2.338 | 1.275 | 0.6802 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7422 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 80</span>| 458.08069 | 0.9973 | -1.438 | -0.9021 | -0.8695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7787 | -0.5135 | -0.7416 | -0.9729 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5880 | -0.6915 | -0.7053 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08069 | 93.75 | -5.838 | -0.9809 | -0.1741 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.170 | 2.338 | 1.275 | 0.6807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7420 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08069</span> | 93.75 | 0.002915 | 0.2727 | 0.8402 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.762 | 2.338 | 1.275 | 0.6807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7420 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.424 | 0.2112 | 0.1114 | -0.1426 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5267 | -0.3290 | -0.02249 | 0.9218 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.516 | 0.4273 | -0.4325 | 0.09748 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 81</span>| 458.08076 | 0.9972 | -1.438 | -0.9021 | -0.8695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7786 | -0.5134 | -0.7416 | -0.9730 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5880 | -0.6914 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08076 | 93.74 | -5.838 | -0.9810 | -0.1741 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.170 | 2.338 | 1.275 | 0.6807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08076</span> | 93.74 | 0.002915 | 0.2727 | 0.8402 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.763 | 2.338 | 1.275 | 0.6807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 82</span>| 458.08078 | 0.9973 | -1.438 | -0.9021 | -0.8695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7787 | -0.5135 | -0.7416 | -0.9730 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5880 | -0.6915 | -0.7053 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08078 | 93.74 | -5.838 | -0.9809 | -0.1741 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.170 | 2.338 | 1.275 | 0.6807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08078</span> | 93.74 | 0.002915 | 0.2727 | 0.8402 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.762 | 2.338 | 1.275 | 0.6807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 83</span>| 458.08068 | 0.9973 | -1.438 | -0.9021 | -0.8695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7787 | -0.5135 | -0.7416 | -0.9729 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5880 | -0.6915 | -0.7053 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08068 | 93.75 | -5.838 | -0.9809 | -0.1741 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.170 | 2.338 | 1.275 | 0.6807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7420 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08068</span> | 93.75 | 0.002915 | 0.2727 | 0.8402 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.762 | 2.338 | 1.275 | 0.6807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7420 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 0.7458 | 0.2086 | 0.07146 | -0.1568 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5453 | -0.1723 | 0.1066 | 0.6006 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.05957 | 0.1717 | -0.3314 | 0.06442 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 84</span>| 458.08065 | 0.9973 | -1.438 | -0.9021 | -0.8695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7787 | -0.5135 | -0.7416 | -0.9729 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5880 | -0.6915 | -0.7053 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08065 | 93.74 | -5.838 | -0.9809 | -0.1741 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.170 | 2.338 | 1.275 | 0.6807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7420 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08065</span> | 93.74 | 0.002915 | 0.2727 | 0.8402 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.762 | 2.338 | 1.275 | 0.6807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7420 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 0.5271 | 0.2085 | 0.07055 | -0.1570 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5454 | -0.3138 | 0.09492 | 0.7765 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.192 | 0.4934 | -0.3382 | 0.1071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 85</span>| 458.08062 | 0.9973 | -1.438 | -0.9021 | -0.8695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7786 | -0.5135 | -0.7416 | -0.9730 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5880 | -0.6915 | -0.7054 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08062 | 93.74 | -5.838 | -0.9809 | -0.1741 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.170 | 2.338 | 1.275 | 0.6807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7420 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08062</span> | 93.74 | 0.002915 | 0.2727 | 0.8402 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.762 | 2.338 | 1.275 | 0.6807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7420 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 0.1077 | 0.2083 | 0.06880 | -0.1572 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5469 | -0.1727 | 0.1219 | 0.9565 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.457 | 0.5128 | -0.3399 | 0.1022 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 86</span>| 458.08061 | 0.9972 | -1.438 | -0.9021 | -0.8695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7786 | -0.5135 | -0.7416 | -0.9730 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5881 | -0.6914 | -0.7054 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08061 | 93.74 | -5.838 | -0.9809 | -0.1741 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.170 | 2.338 | 1.275 | 0.6807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08061</span> | 93.74 | 0.002915 | 0.2727 | 0.8402 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.763 | 2.338 | 1.275 | 0.6807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -0.6930 | 0.2078 | 0.06712 | -0.1577 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5484 | -0.1767 | 0.1148 | 0.9863 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2038 | 0.5855 | -0.3296 | 0.1002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 87</span>| 458.08058 | 0.9972 | -1.438 | -0.9021 | -0.8695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7786 | -0.5135 | -0.7416 | -0.9731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5881 | -0.6914 | -0.7054 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08058 | 93.74 | -5.838 | -0.9809 | -0.1741 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6806 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08058</span> | 93.74 | 0.002915 | 0.2727 | 0.8402 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.763 | 2.338 | 1.275 | 0.6806 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -0.3701 | 0.2079 | 0.06808 | -0.1573 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5470 | -0.1729 | 0.005725 | 0.9526 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.465 | 0.5101 | -0.1466 | -0.02770 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 88</span>| 458.08052 | 0.9973 | -1.438 | -0.9021 | -0.8695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7785 | -0.5135 | -0.7416 | -0.9731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5881 | -0.6914 | -0.7053 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08052 | 93.74 | -5.838 | -0.9809 | -0.1741 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6806 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08052</span> | 93.74 | 0.002915 | 0.2727 | 0.8402 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.763 | 2.338 | 1.275 | 0.6806 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 0.2062 | 0.2080 | 0.06837 | -0.1566 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5439 | -0.1704 | 0.09858 | 0.5928 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.05984 | 0.5131 | -0.3447 | 0.06046 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 89</span>| 458.08047 | 0.9972 | -1.438 | -0.9021 | -0.8694 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7785 | -0.5134 | -0.7416 | -0.9732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5882 | -0.6914 | -0.7054 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08047 | 93.74 | -5.838 | -0.9809 | -0.1741 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6805 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08047</span> | 93.74 | 0.002915 | 0.2727 | 0.8402 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.764 | 2.338 | 1.275 | 0.6805 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -0.06148 | 0.2077 | 0.06828 | -0.1566 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5434 | -0.1748 | 0.1045 | 0.7316 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7607 | 0.4924 | -0.3350 | 0.1046 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 90</span>| 458.08041 | 0.9972 | -1.438 | -0.9021 | -0.8694 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7784 | -0.5134 | -0.7417 | -0.9733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5883 | -0.6913 | -0.7054 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08041 | 93.74 | -5.838 | -0.9810 | -0.1740 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6804 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08041</span> | 93.74 | 0.002915 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.765 | 2.338 | 1.275 | 0.6804 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7421 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -0.5076 | 0.2073 | 0.06528 | -0.1564 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5454 | -0.1802 | 0.1061 | 0.9740 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1992 | 0.5430 | -0.2714 | 0.1031 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 91</span>| 458.08026 | 0.9972 | -1.438 | -0.9022 | -0.8694 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7782 | -0.5133 | -0.7417 | -0.9736 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5884 | -0.6912 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08026 | 93.74 | -5.838 | -0.9810 | -0.1740 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6802 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7422 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08026</span> | 93.74 | 0.002914 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.766 | 2.338 | 1.275 | 0.6802 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7422 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -0.3779 | 0.2092 | 0.07455 | -0.1547 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5349 | 0.4172 | -0.5362 | 0.7903 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.451 | 0.5182 | -0.2163 | -0.4361 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 92</span>| 458.08039 | 0.9975 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7778 | -0.5133 | -0.7416 | -0.9742 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5887 | -0.6910 | -0.7056 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08039 | 93.76 | -5.838 | -0.9811 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6798 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7424 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08039</span> | 93.76 | 0.002914 | 0.2727 | 0.8404 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.769 | 2.338 | 1.275 | 0.6798 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7424 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 93</span>| 458.08025 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08025 | 93.75 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08025</span> | 93.75 | 0.002914 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 1.019 | 0.2066 | 0.06601 | -0.1530 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5270 | -0.1637 | 0.1163 | 0.9184 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.439 | 0.4715 | -0.2217 | 0.03756 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 94</span>| 458.08029 | 0.9972 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08029 | 93.74 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7424 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08029</span> | 93.74 | 0.002914 | 0.2727 | 0.8404 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7424 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 95</span>| 458.08025 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08025 | 93.74 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7424 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08025</span> | 93.74 | 0.002914 | 0.2727 | 0.8404 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7424 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 96</span>| 458.08029 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08029 | 93.75 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08029</span> | 93.75 | 0.002914 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 97</span>| 458.08024 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08024 | 93.75 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08024</span> | 93.75 | 0.002914 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 0.9275 | 0.2065 | 0.06562 | -0.1530 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5278 | -0.1682 | 0.1168 | 0.9523 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1838 | 0.4888 | -0.3154 | 0.09539 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 98</span>| 458.08024 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08024 | 93.75 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08024</span> | 93.75 | 0.002914 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 0.8715 | 0.2065 | 0.06540 | -0.1531 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5308 | -0.07756 | 0.1164 | 0.5595 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.04465 | -0.2577 | -0.3240 | 0.1066 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 99</span>| 458.08023 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08023 | 93.75 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08023</span> | 93.75 | 0.002914 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 100</span>| 458.08013 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08013 | 93.75 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08013</span> | 93.75 | 0.002914 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 0.7255 | 0.2064 | 0.06482 | -0.1531 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5283 | -0.1617 | 0.1081 | 0.9192 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.441 | 0.4906 | -0.2900 | 0.1161 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 101</span>| 458.08017 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5885 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08017 | 93.74 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08017</span> | 93.74 | 0.002914 | 0.2727 | 0.8404 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 102</span>| 458.08021 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08021 | 93.74 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08021</span> | 93.74 | 0.002914 | 0.2727 | 0.8404 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 103</span>| 458.08029 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08029 | 93.75 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08029</span> | 93.75 | 0.002914 | 0.2727 | 0.8404 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 104</span>| 458.08032 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08032 | 93.75 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08032</span> | 93.75 | 0.002914 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 105</span>| 458.08033 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08033 | 93.75 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08033</span> | 93.75 | 0.002914 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 106</span>| 458.08032 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08032 | 93.75 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08032</span> | 93.75 | 0.002914 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 107</span>| 458.08032 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08032 | 93.75 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08032</span> | 93.75 | 0.002914 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 108</span>| 458.08032 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08032 | 93.75 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08032</span> | 93.75 | 0.002914 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 109</span>| 458.08032 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08032 | 93.75 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08032</span> | 93.75 | 0.002914 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 110</span>| 458.08032 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08032 | 93.75 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08032</span> | 93.75 | 0.002914 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 111</span>| 458.08032 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08032 | 93.75 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08032</span> | 93.75 | 0.002914 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 112</span>| 458.08032 | 0.9973 | -1.438 | -0.9022 | -0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7780 | -0.5133 | -0.7416 | -0.9739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.5886 | -0.6911 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.08032 | 93.75 | -5.838 | -0.9810 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.171 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.08032</span> | 93.75 | 0.002914 | 0.2727 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.768 | 2.338 | 1.275 | 0.6800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7423 | 1.521 | 1.288 | 1.311 |</span> +<span class="r-out co"><span class="r-pr">#></span> calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>initial ETAs were nudged; (can control by foceiControl(etaNudge=., etaNudge2=))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>ETAs were reset to zero during optimization; (Can control by foceiControl(resetEtaP=.))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>last objective function was not at minimum, possible problems in optimization</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>gradient problems with initial estimate and covariance; see $scaleInfo</span> +<span class="r-in"><span class="va">f_nlmixr_dfop_sfo_saem_obs</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_obs</span><span class="op">[</span><span class="st">"DFOP-SFO"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"saem"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → generate SAEM model</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-out co"><span class="r-pr">#></span> 1: 93.0952 -5.6337 -1.8988 -4.1294 -1.2035 0.1038 5.2152 1.6150 1.0450 2.6377 0.5035 0.5225 20.0768 11.4566</span> +<span class="r-out co"><span class="r-pr">#></span> 2: 93.1464 -5.6948 -1.8729 -4.2029 -1.1302 0.1295 5.5478 1.5342 0.9927 2.5059 0.4783 0.5147 11.2089 8.1577</span> +<span class="r-out co"><span class="r-pr">#></span> 3: 93.1719 -5.7029 -1.8810 -4.2024 -1.0686 0.1063 5.2764 1.5217 0.9431 2.3806 0.4544 0.5587 9.3753 5.7166</span> +<span class="r-out co"><span class="r-pr">#></span> 4: 92.8647 -5.8139 -1.8979 -4.1992 -1.0168 0.1122 5.4892 1.7893 0.8960 2.2615 0.4317 0.5307 9.4134 4.7166</span> +<span class="r-out co"><span class="r-pr">#></span> 5: 92.7759 -5.8627 -1.8873 -4.1402 -1.0347 0.1243 6.2028 2.1819 0.8795 2.1485 0.4101 0.5042 9.5964 4.7340</span> +<span class="r-out co"><span class="r-pr">#></span> 6: 92.8080 -5.8954 -1.9186 -4.1772 -0.9727 0.1311 5.8926 2.0728 0.8633 2.0410 0.3896 0.4790 8.7334 4.1957</span> +<span class="r-out co"><span class="r-pr">#></span> 7: 92.9042 -5.9034 -1.9603 -4.1854 -0.9717 0.1630 5.5980 2.2068 0.8672 1.9390 0.3701 0.4550 8.7213 3.3409</span> +<span class="r-out co"><span class="r-pr">#></span> 8: 92.9302 -5.8545 -1.9240 -4.2343 -0.9748 0.1686 5.3181 2.3934 0.8239 1.9533 0.3516 0.4323 7.6950 2.9174</span> +<span class="r-out co"><span class="r-pr">#></span> 9: 92.9518 -5.5561 -1.9734 -4.1856 -0.9322 0.2129 5.0522 2.2738 0.7830 2.0138 0.3340 0.4689 7.9230 2.1930</span> +<span class="r-out co"><span class="r-pr">#></span> 10: 93.0672 -5.5564 -1.9633 -4.1456 -0.9343 0.2049 4.7996 2.1601 0.7438 2.0517 0.3173 0.4771 8.0644 2.0682</span> +<span class="r-out co"><span class="r-pr">#></span> 11: 92.6849 -5.6187 -1.9773 -4.1793 -0.9342 0.2290 4.5596 2.0521 0.7123 2.0774 0.3015 0.5052 8.2355 1.9349</span> +<span class="r-out co"><span class="r-pr">#></span> 12: 92.6425 -5.6989 -2.0144 -4.1395 -0.9342 0.2669 4.3316 2.2634 0.7142 2.3008 0.2864 0.5728 7.5188 1.8028</span> +<span class="r-out co"><span class="r-pr">#></span> 13: 92.2996 -5.6700 -1.9885 -4.0443 -0.9202 0.2750 4.5787 2.1608 0.7019 2.7515 0.2721 0.6641 7.0744 1.8958</span> +<span class="r-out co"><span class="r-pr">#></span> 14: 92.2457 -5.5825 -2.0314 -3.9788 -0.9142 0.2908 6.3744 2.0527 0.7018 3.2703 0.2585 0.6387 6.9499 1.8421</span> +<span class="r-out co"><span class="r-pr">#></span> 15: 92.1741 -5.5333 -2.0318 -3.9664 -0.9059 0.2894 6.0557 1.9501 0.7179 3.2869 0.2455 0.6068 7.0951 1.6824</span> +<span class="r-out co"><span class="r-pr">#></span> 16: 92.5772 -5.4982 -2.0352 -3.9471 -0.9063 0.2930 5.7529 1.8526 0.7244 3.6994 0.2333 0.5764 7.2138 1.7042</span> +<span class="r-out co"><span class="r-pr">#></span> 17: 92.7024 -5.4902 -2.0438 -4.0347 -0.9079 0.2959 5.4652 1.7600 0.7393 3.5144 0.2216 0.5765 7.0258 1.6793</span> +<span class="r-out co"><span class="r-pr">#></span> 18: 92.0240 -5.5539 -2.0520 -3.9601 -0.9079 0.2884 6.5142 1.9232 0.7320 3.9052 0.2157 0.5521 7.2568 1.6151</span> +<span class="r-out co"><span class="r-pr">#></span> 19: 92.6532 -5.6325 -2.0456 -3.9091 -0.9179 0.3047 6.5743 2.3363 0.7405 4.5825 0.2049 0.5425 7.6201 1.6565</span> +<span class="r-out co"><span class="r-pr">#></span> 20: 92.3488 -5.6617 -2.0554 -3.9501 -0.9216 0.3056 6.7080 2.7562 0.7218 4.7569 0.2083 0.5432 7.3481 1.8059</span> +<span class="r-out co"><span class="r-pr">#></span> 21: 92.5679 -5.7469 -2.0614 -4.0829 -0.8890 0.3158 6.6510 3.1993 0.7136 4.5191 0.1978 0.5281 7.3723 1.7461</span> +<span class="r-out co"><span class="r-pr">#></span> 22: 92.4785 -5.9527 -2.0657 -4.0580 -0.8971 0.3084 6.3184 4.1791 0.7144 4.2931 0.1929 0.5157 7.1922 1.6984</span> +<span class="r-out co"><span class="r-pr">#></span> 23: 92.5594 -5.8590 -2.0723 -4.0580 -0.9020 0.2952 6.0025 3.9702 0.7335 4.0784 0.1833 0.5129 7.7560 1.6302</span> +<span class="r-out co"><span class="r-pr">#></span> 24: 92.6152 -5.9488 -2.0658 -4.1187 -0.9050 0.2997 5.7024 4.5381 0.7215 3.8745 0.1875 0.5129 7.6182 1.6362</span> +<span class="r-out co"><span class="r-pr">#></span> 25: 92.4658 -5.8715 -2.0791 -4.0949 -0.8922 0.3074 6.1428 4.3112 0.7353 3.6808 0.1896 0.5157 7.2703 1.5633</span> +<span class="r-out co"><span class="r-pr">#></span> 26: 92.2507 -5.9797 -2.0707 -4.0834 -0.8868 0.3266 6.4124 4.7125 0.7334 3.5368 0.1851 0.5217 7.3085 1.5828</span> +<span class="r-out co"><span class="r-pr">#></span> 27: 92.7055 -5.9792 -2.0779 -4.2066 -0.8887 0.2993 6.0918 4.8624 0.7659 3.7456 0.1841 0.4956 7.3534 1.5240</span> +<span class="r-out co"><span class="r-pr">#></span> 28: 92.3971 -6.0253 -2.0648 -4.1406 -0.9042 0.2897 5.7872 4.7690 0.7449 3.5583 0.1823 0.4709 7.2479 1.5008</span> +<span class="r-out co"><span class="r-pr">#></span> 29: 92.4045 -5.9045 -2.0730 -4.1407 -0.8969 0.3103 5.6683 4.5306 0.7349 3.3816 0.1849 0.5054 7.1719 1.6004</span> +<span class="r-out co"><span class="r-pr">#></span> 30: 92.1714 -5.8598 -2.0645 -4.0913 -0.8964 0.2743 5.3849 4.3040 0.7538 3.3509 0.1757 0.4801 7.3739 1.5736</span> +<span class="r-out co"><span class="r-pr">#></span> 31: 91.9134 -5.7867 -2.0367 -4.0563 -0.8957 0.2280 5.1156 4.0888 0.7299 3.3452 0.1749 0.4673 6.5991 1.5909</span> +<span class="r-out co"><span class="r-pr">#></span> 32: 92.3743 -5.9967 -2.0255 -4.0668 -0.9025 0.2247 4.8599 4.6666 0.7256 3.3271 0.1714 0.5008 6.4693 1.5458</span> +<span class="r-out co"><span class="r-pr">#></span> 33: 92.5239 -5.9301 -2.0387 -4.0365 -0.9033 0.2558 4.6169 4.4333 0.7492 3.6109 0.1688 0.5424 6.7730 1.5771</span> +<span class="r-out co"><span class="r-pr">#></span> 34: 92.6892 -6.1135 -2.0587 -4.0280 -0.8993 0.2430 4.3860 6.0227 0.7798 3.5725 0.1672 0.5153 6.8110 1.5417</span> +<span class="r-out co"><span class="r-pr">#></span> 35: 92.7276 -6.0815 -2.0629 -4.0833 -0.8943 0.2375 4.6811 5.7216 0.8010 3.3939 0.1715 0.4895 6.6812 1.5478</span> +<span class="r-out co"><span class="r-pr">#></span> 36: 92.7316 -6.0691 -2.0882 -4.0626 -0.9030 0.2405 4.4614 5.4355 0.8355 3.2242 0.1789 0.4650 6.8443 1.4806</span> +<span class="r-out co"><span class="r-pr">#></span> 37: 92.6685 -5.7905 -2.0666 -4.0663 -0.8998 0.2784 5.1916 5.1637 0.7937 3.0641 0.1823 0.4418 6.5421 1.6284</span> +<span class="r-out co"><span class="r-pr">#></span> 38: 93.0325 -5.6829 -2.0674 -4.0772 -0.9167 0.2499 4.9320 4.9055 0.7768 3.1213 0.1887 0.4290 6.8220 1.5224</span> +<span class="r-out co"><span class="r-pr">#></span> 39: 93.0378 -5.5554 -2.0743 -4.0772 -0.9189 0.2361 4.6854 4.6603 0.7822 3.1213 0.1813 0.4242 7.1137 1.5021</span> +<span class="r-out co"><span class="r-pr">#></span> 40: 93.3297 -5.6270 -2.0591 -4.1200 -0.9167 0.2035 4.4511 4.4272 0.8128 2.9653 0.1829 0.4030 7.3894 1.5064</span> +<span class="r-out co"><span class="r-pr">#></span> 41: 93.3408 -5.5437 -2.0344 -4.1042 -0.9078 0.1744 4.2286 4.2059 0.8228 2.8170 0.1881 0.3829 7.2734 1.5519</span> +<span class="r-out co"><span class="r-pr">#></span> 42: 93.1691 -5.4436 -2.0551 -4.1048 -0.8984 0.1732 4.0172 3.9956 0.7816 2.6762 0.1853 0.3637 6.9712 1.5332</span> +<span class="r-out co"><span class="r-pr">#></span> 43: 93.2443 -5.5247 -2.0722 -4.0980 -0.8992 0.1756 3.8163 3.7958 0.7781 2.7200 0.1956 0.3455 6.7012 1.5344</span> +<span class="r-out co"><span class="r-pr">#></span> 44: 92.9509 -5.5020 -2.0495 -4.0961 -0.8964 0.1777 3.6255 3.6060 0.7555 2.8172 0.1994 0.3283 6.2180 1.6137</span> +<span class="r-out co"><span class="r-pr">#></span> 45: 92.8898 -5.4913 -2.0462 -4.1079 -0.9003 0.1701 4.1177 3.4257 0.7491 2.8491 0.1989 0.3372 6.2876 1.6205</span> +<span class="r-out co"><span class="r-pr">#></span> 46: 92.6044 -5.6429 -2.0499 -4.1079 -0.9069 0.1999 4.2103 3.2544 0.7657 2.8491 0.1921 0.3532 6.2261 1.6435</span> +<span class="r-out co"><span class="r-pr">#></span> 47: 92.7740 -5.6128 -2.0804 -4.1186 -0.8976 0.1864 5.2188 3.0917 0.7381 2.9036 0.2030 0.3391 6.6803 1.6177</span> +<span class="r-out co"><span class="r-pr">#></span> 48: 92.4691 -5.6645 -2.0600 -4.1288 -0.8796 0.1913 6.2045 2.9371 0.7774 2.9223 0.1966 0.3396 6.7169 1.6215</span> +<span class="r-out co"><span class="r-pr">#></span> 49: 92.4128 -5.7079 -2.0802 -4.1166 -0.8798 0.1741 5.8943 3.1446 0.7854 2.8715 0.1935 0.3369 6.9151 1.4834</span> +<span class="r-out co"><span class="r-pr">#></span> 50: 91.8883 -5.7713 -2.0932 -4.0899 -0.8886 0.1758 5.5996 3.5478 0.8033 2.8192 0.2014 0.3201 7.0775 1.4635</span> +<span class="r-out co"><span class="r-pr">#></span> 51: 92.1187 -5.7306 -2.0903 -4.0878 -0.8923 0.2024 5.3196 3.6534 0.7823 2.7891 0.1969 0.3140 6.9879 1.5430</span> +<span class="r-out co"><span class="r-pr">#></span> 52: 92.3209 -5.7897 -2.0903 -4.1622 -0.9072 0.2261 5.3781 3.4707 0.8001 3.0801 0.2063 0.3088 6.7047 1.4499</span> +<span class="r-out co"><span class="r-pr">#></span> 53: 92.4318 -5.6954 -2.0950 -4.1866 -0.9082 0.2131 7.1200 3.2972 0.7711 3.3398 0.2034 0.3186 6.6152 1.5123</span> +<span class="r-out co"><span class="r-pr">#></span> 54: 92.5380 -5.6975 -2.0782 -4.2394 -0.8976 0.2118 6.7640 3.1323 0.7744 3.5385 0.2175 0.3296 6.4402 1.5403</span> +<span class="r-out co"><span class="r-pr">#></span> 55: 92.7213 -5.6663 -2.0427 -4.3288 -0.9028 0.2032 8.1796 2.9757 0.7748 4.4495 0.2142 0.3316 6.4111 1.5369</span> +<span class="r-out co"><span class="r-pr">#></span> 56: 92.7219 -5.6865 -2.0557 -4.3434 -0.9084 0.2021 7.7706 2.8269 0.7989 4.6691 0.2174 0.3433 6.4256 1.4639</span> +<span class="r-out co"><span class="r-pr">#></span> 57: 92.8932 -5.5736 -2.0497 -4.3955 -0.9216 0.1694 7.3821 2.6856 0.8205 4.9791 0.2142 0.3500 6.5378 1.5406</span> +<span class="r-out co"><span class="r-pr">#></span> 58: 92.9219 -5.5789 -2.0547 -4.3094 -0.9183 0.1838 7.0130 2.5513 0.7958 4.7302 0.2193 0.3495 6.2662 1.4940</span> +<span class="r-out co"><span class="r-pr">#></span> 59: 93.0432 -5.6201 -2.0395 -4.2527 -0.9199 0.2302 6.6623 2.4237 0.8241 4.4937 0.2241 0.3321 5.8693 1.6176</span> +<span class="r-out co"><span class="r-pr">#></span> 60: 92.9724 -5.5971 -2.0537 -4.3509 -0.9219 0.2118 7.5905 2.3026 0.8418 4.4546 0.2177 0.3155 5.5960 1.5040</span> +<span class="r-out co"><span class="r-pr">#></span> 61: 93.1235 -5.6332 -2.0671 -4.3572 -0.9219 0.1917 7.2521 2.3037 0.8527 4.5707 0.2230 0.2997 5.8136 1.4516</span> +<span class="r-out co"><span class="r-pr">#></span> 62: 93.5431 -5.6373 -2.0371 -4.3384 -0.9276 0.1997 8.5187 2.3895 0.8575 4.4378 0.2258 0.3041 5.5746 1.4572</span> +<span class="r-out co"><span class="r-pr">#></span> 63: 93.5009 -5.5634 -2.0224 -4.3560 -0.9339 0.2167 8.0927 2.2700 0.8462 4.4449 0.2266 0.3162 5.4922 1.5233</span> +<span class="r-out co"><span class="r-pr">#></span> 64: 93.7369 -5.6032 -2.0362 -4.2323 -0.9355 0.2159 9.6684 2.1949 0.8514 4.2227 0.2300 0.3318 5.7597 1.4866</span> +<span class="r-out co"><span class="r-pr">#></span> 65: 93.5021 -5.5769 -2.0311 -4.3204 -0.9375 0.1927 9.5537 2.0852 0.8559 4.6151 0.2208 0.3550 5.6975 1.5031</span> +<span class="r-out co"><span class="r-pr">#></span> 66: 93.4211 -5.7184 -2.0384 -4.3041 -0.9228 0.2121 9.0760 2.6390 0.8430 4.3843 0.2098 0.3755 5.8990 1.5133</span> +<span class="r-out co"><span class="r-pr">#></span> 67: 93.3435 -5.6579 -2.0456 -4.2222 -0.9183 0.1825 8.6222 2.5071 0.8719 4.1651 0.2152 0.3567 5.9004 1.4874</span> +<span class="r-out co"><span class="r-pr">#></span> 68: 93.3914 -5.6554 -2.0420 -4.1618 -0.9303 0.1714 8.1911 2.3817 0.8856 3.9569 0.2272 0.3388 6.1793 1.4917</span> +<span class="r-out co"><span class="r-pr">#></span> 69: 93.5112 -5.6834 -2.0349 -4.1591 -0.9331 0.1759 8.9900 2.5191 0.9184 3.7590 0.2236 0.3219 6.1618 1.4697</span> +<span class="r-out co"><span class="r-pr">#></span> 70: 93.4289 -5.6576 -2.0273 -4.1763 -0.9399 0.1738 8.5405 2.4302 0.8725 3.5711 0.2149 0.3288 6.5324 1.5410</span> +<span class="r-out co"><span class="r-pr">#></span> 71: 93.2936 -5.6699 -2.0256 -4.1405 -0.9370 0.1922 8.1134 2.3831 0.8289 3.3925 0.2080 0.3548 5.9794 1.5904</span> +<span class="r-out co"><span class="r-pr">#></span> 72: 92.9152 -5.6742 -2.0382 -4.1523 -0.9411 0.1991 7.7078 2.4322 0.7875 3.2916 0.2007 0.3456 6.0999 1.6022</span> +<span class="r-out co"><span class="r-pr">#></span> 73: 92.8129 -5.8099 -2.0372 -4.1735 -0.9377 0.1605 8.2752 2.8931 0.7737 3.4015 0.2057 0.3283 6.0140 1.5472</span> +<span class="r-out co"><span class="r-pr">#></span> 74: 92.7806 -5.7269 -2.0315 -4.1877 -0.9399 0.1675 8.4688 2.7484 0.7773 3.4620 0.2174 0.3249 5.8495 1.5779</span> +<span class="r-out co"><span class="r-pr">#></span> 75: 92.9128 -5.8680 -2.0304 -4.1459 -0.9387 0.1567 8.0454 3.2365 0.7681 3.2935 0.2198 0.3187 5.8539 1.5815</span> +<span class="r-out co"><span class="r-pr">#></span> 76: 92.8931 -5.8483 -2.0253 -4.1815 -0.9387 0.1540 9.6800 3.0747 0.8007 3.5838 0.2198 0.3291 5.9005 1.5053</span> +<span class="r-out co"><span class="r-pr">#></span> 77: 92.7474 -5.7995 -2.0202 -4.1904 -0.9333 0.1724 10.0488 2.9210 0.7841 3.7255 0.2148 0.3465 5.9418 1.5569</span> +<span class="r-out co"><span class="r-pr">#></span> 78: 92.8150 -5.9608 -2.0025 -4.1583 -0.9511 0.1566 9.5464 3.5249 0.7858 3.6988 0.2246 0.3292 5.7737 1.5904</span> +<span class="r-out co"><span class="r-pr">#></span> 79: 92.6663 -6.0485 -2.0245 -4.1437 -0.9446 0.1786 9.0690 4.1252 0.7803 3.6526 0.2155 0.3335 5.9109 1.5521</span> +<span class="r-out co"><span class="r-pr">#></span> 80: 92.5932 -6.1001 -2.0304 -4.1969 -0.9409 0.1424 8.6156 4.6478 0.8007 4.0379 0.2114 0.3168 6.1732 1.5544</span> +<span class="r-out co"><span class="r-pr">#></span> 81: 92.6789 -6.3510 -2.0062 -4.2272 -0.9541 0.1360 8.3363 5.9861 0.7719 3.8800 0.2202 0.3010 5.6841 1.6317</span> +<span class="r-out co"><span class="r-pr">#></span> 82: 92.9996 -6.5680 -2.0048 -4.1609 -0.9578 0.1367 10.6901 7.4391 0.7962 3.6860 0.2092 0.2859 5.7335 1.6391</span> +<span class="r-out co"><span class="r-pr">#></span> 83: 93.1087 -6.5298 -1.9757 -4.1694 -0.9596 0.1323 10.5524 7.4660 0.8237 3.8009 0.2134 0.2716 5.9664 1.6316</span> +<span class="r-out co"><span class="r-pr">#></span> 84: 93.1929 -6.5844 -2.0191 -4.2021 -0.9616 0.1384 10.0248 7.7313 0.8230 3.6109 0.2110 0.2580 5.7854 1.5609</span> +<span class="r-out co"><span class="r-pr">#></span> 85: 92.9161 -6.4934 -2.0281 -4.2008 -0.9600 0.1107 9.5236 7.4269 0.8448 3.5630 0.2110 0.2451 5.6111 1.5333</span> +<span class="r-out co"><span class="r-pr">#></span> 86: 92.9816 -6.5397 -2.0234 -4.1830 -0.9694 0.1111 9.1945 7.4382 0.8481 3.3849 0.2166 0.2329 5.8375 1.5263</span> +<span class="r-out co"><span class="r-pr">#></span> 87: 93.0930 -6.5749 -2.0168 -4.1986 -0.9816 0.0926 8.7348 8.4431 0.8646 3.3032 0.2155 0.2212 5.7542 1.5736</span> +<span class="r-out co"><span class="r-pr">#></span> 88: 93.0765 -6.4914 -2.0274 -4.2274 -0.9870 0.1148 8.4666 8.0209 0.8666 3.5292 0.2048 0.2102 5.8988 1.5329</span> +<span class="r-out co"><span class="r-pr">#></span> 89: 92.8699 -6.6431 -2.0199 -4.2175 -0.9463 0.1011 8.4648 7.7973 0.8908 3.3980 0.1945 0.2102 5.6876 1.5177</span> +<span class="r-out co"><span class="r-pr">#></span> 90: 92.8225 -6.6932 -2.0211 -4.2175 -0.9505 0.0887 10.1862 8.7787 0.8730 3.3980 0.1877 0.1997 5.9135 1.4821</span> +<span class="r-out co"><span class="r-pr">#></span> 91: 92.7874 -6.7007 -2.0420 -4.2936 -0.9468 0.0927 11.2275 8.3397 0.8600 3.9490 0.1885 0.2147 6.1108 1.4315</span> +<span class="r-out co"><span class="r-pr">#></span> 92: 93.2320 -6.8088 -2.0341 -4.2817 -0.9582 0.1270 12.4029 9.6204 0.8503 3.7516 0.1950 0.2070 5.9434 1.5251</span> +<span class="r-out co"><span class="r-pr">#></span> 93: 93.8996 -6.5471 -2.0440 -4.2123 -0.9543 0.1140 11.7828 9.1394 0.8493 3.5640 0.1988 0.2017 6.1302 1.5568</span> +<span class="r-out co"><span class="r-pr">#></span> 94: 93.4416 -6.4623 -2.0448 -4.2188 -0.9595 0.1174 12.1277 8.6824 0.8568 3.3858 0.1975 0.1938 5.9173 1.5204</span> +<span class="r-out co"><span class="r-pr">#></span> 95: 93.2953 -6.1521 -2.0477 -4.2216 -0.9551 0.1152 11.5213 8.2483 0.8356 3.2165 0.1979 0.1855 5.8298 1.5357</span> +<span class="r-out co"><span class="r-pr">#></span> 96: 92.9577 -6.0477 -2.0579 -4.2534 -0.9465 0.1284 10.9452 7.8359 0.8202 3.3357 0.1937 0.1917 5.8590 1.5738</span> +<span class="r-out co"><span class="r-pr">#></span> 97: 92.8703 -6.1037 -2.0745 -4.1960 -0.9405 0.1417 10.4858 7.4441 0.8488 3.1690 0.1969 0.2016 5.7948 1.4759</span> +<span class="r-out co"><span class="r-pr">#></span> 98: 92.9728 -6.3534 -2.0868 -4.2155 -0.9444 0.1069 9.9615 7.1788 0.8736 3.1913 0.1998 0.2114 5.6533 1.4322</span> +<span class="r-out co"><span class="r-pr">#></span> 99: 93.4116 -6.1712 -2.0837 -4.2280 -0.9473 0.1197 9.4634 6.8198 0.8959 3.1806 0.1899 0.2167 5.9149 1.3768</span> +<span class="r-out co"><span class="r-pr">#></span> 100: 93.2598 -6.1345 -2.0645 -4.2237 -0.9575 0.1099 8.9903 6.4788 0.9204 3.2429 0.1903 0.2058 5.7085 1.4133</span> +<span class="r-out co"><span class="r-pr">#></span> 101: 93.3082 -6.1574 -2.0474 -4.2315 -0.9619 0.1161 9.0819 6.1549 0.8744 3.2049 0.1891 0.2278 5.6493 1.4894</span> +<span class="r-out co"><span class="r-pr">#></span> 102: 93.5741 -6.2923 -2.0484 -4.2853 -0.9665 0.1325 10.4108 5.8522 0.8804 3.5370 0.2024 0.2324 5.6995 1.4594</span> +<span class="r-out co"><span class="r-pr">#></span> 103: 92.9199 -6.1797 -2.0522 -4.2940 -0.9568 0.1289 9.8903 5.5596 0.8722 3.6682 0.1975 0.2398 5.5536 1.4510</span> +<span class="r-out co"><span class="r-pr">#></span> 104: 93.1139 -6.1630 -2.0546 -4.2912 -0.9613 0.1115 9.3958 5.2816 0.8648 3.6673 0.2010 0.2278 5.5768 1.4812</span> +<span class="r-out co"><span class="r-pr">#></span> 105: 93.4085 -6.0359 -2.0450 -4.2889 -0.9591 0.1258 8.9260 5.0175 0.8412 3.7286 0.1917 0.2171 5.6780 1.5203</span> +<span class="r-out co"><span class="r-pr">#></span> 106: 93.3103 -6.1029 -2.0425 -4.2948 -0.9579 0.0934 8.4797 4.7667 0.8539 3.6947 0.1947 0.2234 5.7210 1.4760</span> +<span class="r-out co"><span class="r-pr">#></span> 107: 93.6389 -5.9750 -2.0309 -4.2630 -0.9660 0.1110 8.0557 4.5283 0.8470 3.5100 0.2044 0.2299 5.6280 1.5525</span> +<span class="r-out co"><span class="r-pr">#></span> 108: 93.8641 -5.8551 -2.0360 -4.2311 -0.9629 0.0900 7.6529 4.3019 0.8567 3.3345 0.2014 0.2302 5.7841 1.5978</span> +<span class="r-out co"><span class="r-pr">#></span> 109: 93.6274 -6.0268 -2.0445 -4.3047 -0.9488 0.0979 7.2703 4.7807 0.8565 3.7665 0.1929 0.2271 5.7941 1.5580</span> +<span class="r-out co"><span class="r-pr">#></span> 110: 93.6320 -5.8321 -2.0413 -4.2855 -0.9477 0.1143 6.9068 4.5417 0.8412 3.6165 0.1901 0.2199 5.8169 1.5477</span> +<span class="r-out co"><span class="r-pr">#></span> 111: 93.6245 -5.8256 -2.0157 -4.2797 -0.9612 0.0940 6.5774 4.3146 0.8460 3.5782 0.1837 0.2182 5.6157 1.6424</span> +<span class="r-out co"><span class="r-pr">#></span> 112: 93.8512 -5.9045 -2.0116 -4.2409 -0.9708 0.0883 6.2486 4.0989 0.8658 3.5059 0.1761 0.2073 5.8852 1.6073</span> +<span class="r-out co"><span class="r-pr">#></span> 113: 93.7080 -5.9935 -2.0306 -4.1884 -0.9690 0.0740 5.9361 4.0088 0.9072 3.3400 0.1957 0.2169 6.3792 1.4770</span> +<span class="r-out co"><span class="r-pr">#></span> 114: 93.8574 -5.9185 -2.0233 -4.2030 -0.9588 0.1137 5.6393 3.8084 0.9322 3.2878 0.1939 0.2098 5.8891 1.5325</span> +<span class="r-out co"><span class="r-pr">#></span> 115: 93.7414 -5.8789 -2.0183 -4.2256 -0.9701 0.1105 5.6148 3.6180 0.9222 3.5507 0.1921 0.1993 5.6441 1.5458</span> +<span class="r-out co"><span class="r-pr">#></span> 116: 93.4104 -5.9704 -2.0428 -4.2091 -0.9807 0.1099 5.3341 4.1157 0.9363 3.4004 0.1968 0.2134 5.7764 1.4617</span> +<span class="r-out co"><span class="r-pr">#></span> 117: 93.5239 -5.9057 -2.0518 -4.2494 -0.9812 0.1127 6.8839 3.9099 0.9151 3.6604 0.1921 0.2095 5.4753 1.4249</span> +<span class="r-out co"><span class="r-pr">#></span> 118: 93.7599 -5.9418 -2.0482 -4.2272 -0.9822 0.1094 6.8133 3.7144 0.9198 3.5160 0.1971 0.2039 5.6467 1.4116</span> +<span class="r-out co"><span class="r-pr">#></span> 119: 93.6617 -6.0020 -2.0483 -4.2146 -0.9816 0.1003 6.4727 3.8251 0.9103 3.4716 0.1950 0.2109 5.8513 1.4268</span> +<span class="r-out co"><span class="r-pr">#></span> 120: 93.5436 -5.9804 -2.0458 -4.1906 -0.9819 0.1065 6.1490 3.6756 0.9088 3.2980 0.1989 0.2123 5.8268 1.4689</span> +<span class="r-out co"><span class="r-pr">#></span> 121: 93.4880 -5.9047 -2.0452 -4.1957 -0.9640 0.1349 5.8416 3.4918 0.8824 3.2437 0.1889 0.2017 5.7152 1.4382</span> +<span class="r-out co"><span class="r-pr">#></span> 122: 93.7406 -5.9844 -2.0596 -4.2328 -0.9558 0.1563 5.5495 3.7606 0.8489 3.3043 0.1795 0.2015 5.5095 1.5112</span> +<span class="r-out co"><span class="r-pr">#></span> 123: 93.6728 -6.0394 -2.0372 -4.2812 -0.9592 0.1507 5.2720 4.2004 0.8341 3.5274 0.1817 0.2008 5.6936 1.6011</span> +<span class="r-out co"><span class="r-pr">#></span> 124: 93.9591 -6.0483 -2.0280 -4.2613 -0.9594 0.1463 5.3846 4.1913 0.8351 3.4341 0.1870 0.2193 5.5694 1.5684</span> +<span class="r-out co"><span class="r-pr">#></span> 125: 94.0201 -5.9102 -2.0507 -4.2686 -0.9697 0.1455 5.1154 3.9818 0.8512 3.3475 0.1859 0.2165 5.6224 1.5643</span> +<span class="r-out co"><span class="r-pr">#></span> 126: 93.8825 -5.8970 -2.0543 -4.2569 -0.9663 0.1493 4.9144 3.7827 0.8907 3.3030 0.1876 0.2180 5.7351 1.4722</span> +<span class="r-out co"><span class="r-pr">#></span> 127: 93.9893 -5.8955 -2.0624 -4.2430 -0.9802 0.1476 7.2413 3.5935 0.8915 3.2740 0.1851 0.2110 5.7614 1.4305</span> +<span class="r-out co"><span class="r-pr">#></span> 128: 94.1849 -5.9123 -2.0624 -4.2385 -0.9786 0.1523 7.9575 3.4139 0.9094 3.2656 0.1807 0.2198 5.7366 1.4264</span> +<span class="r-out co"><span class="r-pr">#></span> 129: 94.0812 -6.0044 -2.0696 -4.3056 -0.9770 0.1693 8.7809 3.7526 0.9111 3.6172 0.1859 0.2255 5.8064 1.4718</span> +<span class="r-out co"><span class="r-pr">#></span> 130: 93.6046 -6.1387 -2.0718 -4.3056 -0.9821 0.1477 8.3419 4.3029 0.9177 3.6172 0.1867 0.2143 5.8893 1.4447</span> +<span class="r-out co"><span class="r-pr">#></span> 131: 93.5216 -6.1347 -2.0740 -4.3114 -0.9766 0.1288 8.2937 4.3407 0.9250 3.5298 0.1881 0.2293 5.8054 1.4219</span> +<span class="r-out co"><span class="r-pr">#></span> 132: 93.6142 -6.2789 -2.0786 -4.3297 -0.9716 0.1288 8.3731 5.1225 0.9236 3.6683 0.1929 0.2295 5.8064 1.4194</span> +<span class="r-out co"><span class="r-pr">#></span> 133: 93.4410 -5.9177 -2.0916 -4.3557 -0.9798 0.1066 7.9544 4.8663 0.9537 3.7076 0.1937 0.2279 5.9844 1.4297</span> +<span class="r-out co"><span class="r-pr">#></span> 134: 93.4716 -5.9152 -2.0838 -4.3611 -0.9818 0.1332 7.5567 4.6230 0.9161 3.7833 0.2017 0.2308 6.0611 1.5717</span> +<span class="r-out co"><span class="r-pr">#></span> 135: 93.3787 -6.0381 -2.0728 -4.2627 -0.9719 0.1051 7.2396 4.3919 0.8970 3.5941 0.1916 0.2193 5.8837 1.6057</span> +<span class="r-out co"><span class="r-pr">#></span> 136: 93.4339 -5.9876 -2.0801 -4.3002 -0.9690 0.1214 6.8776 4.1723 0.8888 3.4144 0.2002 0.2227 6.0141 1.5231</span> +<span class="r-out co"><span class="r-pr">#></span> 137: 93.7639 -6.0411 -2.0803 -4.2799 -0.9646 0.1484 6.5337 3.9765 0.8969 3.2437 0.1995 0.2115 5.9404 1.6402</span> +<span class="r-out co"><span class="r-pr">#></span> 138: 93.6414 -6.0122 -2.0714 -4.2666 -0.9755 0.1506 7.4057 3.7962 0.9242 3.1524 0.1934 0.2010 6.0666 1.5001</span> +<span class="r-out co"><span class="r-pr">#></span> 139: 93.7743 -5.7966 -2.0613 -4.2289 -0.9722 0.1383 7.9358 3.6064 0.9015 2.9948 0.1946 0.2029 5.9655 1.5250</span> +<span class="r-out co"><span class="r-pr">#></span> 140: 93.1082 -5.7994 -2.0388 -4.2289 -0.9659 0.1382 8.0282 3.4261 0.9053 2.9079 0.1909 0.2138 5.9183 1.5191</span> +<span class="r-out co"><span class="r-pr">#></span> 141: 93.2122 -6.0181 -2.0396 -4.2398 -0.9587 0.1016 8.9769 3.9426 0.9028 2.9136 0.1941 0.2195 6.1560 1.4902</span> +<span class="r-out co"><span class="r-pr">#></span> 142: 93.4684 -6.1438 -2.0273 -4.2541 -0.9508 0.0848 8.5281 4.8727 0.9056 2.9875 0.1901 0.2233 6.2546 1.4695</span> +<span class="r-out co"><span class="r-pr">#></span> 143: 93.0059 -6.0964 -2.0145 -4.2760 -0.9563 0.0826 8.1017 4.6291 0.9312 3.1063 0.1850 0.2138 6.5768 1.4391</span> +<span class="r-out co"><span class="r-pr">#></span> 144: 93.0612 -6.1127 -1.9951 -4.2589 -0.9539 0.0904 7.6966 4.6160 0.9623 3.1681 0.1824 0.2032 6.1506 1.4497</span> +<span class="r-out co"><span class="r-pr">#></span> 145: 93.5170 -6.1066 -1.9951 -4.3574 -0.9478 0.1040 7.3118 4.6263 0.9639 3.6914 0.1986 0.2292 5.9389 1.4867</span> +<span class="r-out co"><span class="r-pr">#></span> 146: 93.4915 -6.3235 -2.0006 -4.3866 -0.9579 0.1202 6.9462 6.0529 0.9514 3.9899 0.1887 0.2335 5.9265 1.4978</span> +<span class="r-out co"><span class="r-pr">#></span> 147: 93.8963 -6.1119 -2.0055 -4.3446 -0.9682 0.1242 7.1711 5.7503 0.9315 3.7904 0.1923 0.2332 5.9346 1.5021</span> +<span class="r-out co"><span class="r-pr">#></span> 148: 93.6758 -5.9705 -2.0137 -4.2906 -0.9614 0.1125 6.8125 5.4628 0.9506 3.6009 0.1913 0.2371 6.2579 1.4384</span> +<span class="r-out co"><span class="r-pr">#></span> 149: 93.6499 -6.0049 -2.0246 -4.2730 -0.9776 0.0996 6.4719 5.1896 0.9736 3.4209 0.1817 0.2252 6.3224 1.3878</span> +<span class="r-out co"><span class="r-pr">#></span> 150: 94.0242 -5.9760 -2.0176 -4.2182 -0.9773 0.1032 6.1483 4.9301 0.9944 3.2498 0.1807 0.2290 6.5662 1.3618</span> +<span class="r-out co"><span class="r-pr">#></span> 151: 93.9234 -5.8772 -2.0132 -4.2362 -0.9651 0.1058 7.2453 4.6836 0.9824 3.4860 0.1806 0.2175 6.2575 1.4370</span> +<span class="r-out co"><span class="r-pr">#></span> 152: 94.2513 -5.9391 -2.0814 -4.2278 -0.9753 0.1221 4.9753 3.4013 0.9808 3.3265 0.1836 0.1897 6.6966 1.3457</span> +<span class="r-out co"><span class="r-pr">#></span> 153: 93.9434 -6.1294 -2.0570 -4.2447 -0.9761 0.1527 5.0454 4.3115 0.9494 3.3663 0.1684 0.1680 5.9106 1.4777</span> +<span class="r-out co"><span class="r-pr">#></span> 154: 93.8141 -6.2749 -2.0366 -4.2383 -0.9835 0.1440 5.5466 5.3351 0.9320 3.3337 0.1731 0.1913 5.8842 1.4325</span> +<span class="r-out co"><span class="r-pr">#></span> 155: 94.1987 -6.1029 -2.0252 -4.2520 -0.9780 0.1132 7.1508 4.2713 0.9457 3.3428 0.1727 0.1691 6.1632 1.4658</span> +<span class="r-out co"><span class="r-pr">#></span> 156: 94.0626 -6.2640 -2.0263 -4.2461 -0.9854 0.1346 5.6296 5.1645 0.9423 3.3987 0.1697 0.1778 5.9631 1.4483</span> +<span class="r-out co"><span class="r-pr">#></span> 157: 93.9319 -6.1392 -2.0388 -4.2294 -0.9921 0.1265 5.6768 4.7366 0.9210 3.3673 0.1733 0.1789 5.9114 1.4976</span> +<span class="r-out co"><span class="r-pr">#></span> 158: 93.9123 -6.1970 -2.0165 -4.2241 -0.9924 0.1540 7.2552 4.7537 0.9369 3.2727 0.1805 0.1923 5.9324 1.5351</span> +<span class="r-out co"><span class="r-pr">#></span> 159: 93.9704 -6.4018 -2.0455 -4.2127 -0.9919 0.1413 7.7561 6.0732 0.9802 3.3376 0.1806 0.2260 6.4511 1.4227</span> +<span class="r-out co"><span class="r-pr">#></span> 160: 94.1967 -6.2985 -2.0412 -4.2264 -0.9795 0.1206 8.3836 6.1319 0.9689 3.4685 0.1792 0.2150 6.5116 1.4706</span> +<span class="r-out co"><span class="r-pr">#></span> 161: 94.3500 -6.1427 -2.0189 -4.2242 -1.0022 0.0837 8.0282 4.5505 0.9524 3.3269 0.1859 0.1816 6.0642 1.4746</span> +<span class="r-out co"><span class="r-pr">#></span> 162: 94.2711 -5.9578 -2.0215 -4.2078 -1.0110 0.0946 7.8634 3.3072 0.9559 3.2374 0.1876 0.1791 6.0798 1.4903</span> +<span class="r-out co"><span class="r-pr">#></span> 163: 93.9824 -5.8794 -2.0409 -4.2367 -0.9970 0.1150 9.3872 3.0498 0.9830 3.3179 0.1880 0.1828 5.8091 1.4852</span> +<span class="r-out co"><span class="r-pr">#></span> 164: 94.2013 -5.8651 -2.0122 -4.2257 -0.9906 0.1267 7.1953 3.0510 0.9697 3.2713 0.1871 0.1832 5.8741 1.5313</span> +<span class="r-out co"><span class="r-pr">#></span> 165: 94.1804 -5.7868 -2.0200 -4.2053 -0.9812 0.1219 6.7375 2.4769 0.9688 3.2706 0.1910 0.1859 5.7890 1.5188</span> +<span class="r-out co"><span class="r-pr">#></span> 166: 93.9790 -5.8156 -2.0311 -4.2438 -0.9784 0.1247 5.7617 2.6907 0.9533 3.5342 0.1953 0.1872 5.8816 1.5243</span> +<span class="r-out co"><span class="r-pr">#></span> 167: 93.2524 -5.8603 -2.0497 -4.2594 -0.9787 0.1265 4.7086 2.9121 0.9117 3.4696 0.1943 0.1832 5.9672 1.4567</span> +<span class="r-out co"><span class="r-pr">#></span> 168: 93.2924 -6.0371 -2.0528 -4.2607 -0.9727 0.1201 5.5273 4.0286 0.9177 3.4501 0.1918 0.1908 5.7790 1.4701</span> +<span class="r-out co"><span class="r-pr">#></span> 169: 93.4838 -6.1497 -2.0389 -4.2716 -0.9639 0.1127 5.4524 4.2700 0.9544 3.4329 0.1940 0.1871 5.7795 1.4575</span> +<span class="r-out co"><span class="r-pr">#></span> 170: 93.3951 -6.2298 -2.0438 -4.4133 -0.9939 0.1088 6.1460 4.6552 0.9645 4.5240 0.1978 0.2091 5.7549 1.5233</span> +<span class="r-out co"><span class="r-pr">#></span> 171: 93.4113 -6.1187 -2.0536 -4.4019 -0.9771 0.0899 6.8123 4.0073 0.9531 4.4290 0.1878 0.1970 5.9067 1.4857</span> +<span class="r-out co"><span class="r-pr">#></span> 172: 93.1140 -5.9515 -2.0530 -4.3250 -0.9723 0.1094 5.1247 3.4502 0.9572 3.8504 0.1954 0.1944 5.8583 1.4867</span> +<span class="r-out co"><span class="r-pr">#></span> 173: 92.9782 -6.0415 -2.0633 -4.2887 -0.9608 0.1081 4.1020 3.8967 0.9478 3.7222 0.1890 0.1812 5.9473 1.4583</span> +<span class="r-out co"><span class="r-pr">#></span> 174: 92.9661 -5.9295 -2.0457 -4.2907 -0.9626 0.0991 5.7954 3.3581 0.9785 3.7311 0.1867 0.2026 5.8087 1.4797</span> +<span class="r-out co"><span class="r-pr">#></span> 175: 93.2577 -5.8895 -2.0281 -4.2845 -0.9560 0.0829 7.3434 3.1501 0.9975 3.6334 0.1920 0.2151 5.4717 1.4832</span> +<span class="r-out co"><span class="r-pr">#></span> 176: 93.1210 -5.9567 -2.0370 -4.2848 -0.9488 0.0787 6.8946 3.4999 0.9983 3.6159 0.1922 0.2233 5.8426 1.4096</span> +<span class="r-out co"><span class="r-pr">#></span> 177: 92.5456 -6.1797 -2.0319 -4.2684 -0.9401 0.0873 6.9744 5.2939 0.9928 3.4880 0.1989 0.2213 5.9613 1.4367</span> +<span class="r-out co"><span class="r-pr">#></span> 178: 92.6854 -6.1483 -2.0278 -4.2705 -0.9504 0.0630 5.0582 5.0622 0.9953 3.4915 0.1930 0.2238 5.9775 1.4263</span> +<span class="r-out co"><span class="r-pr">#></span> 179: 93.1323 -6.1739 -2.0353 -4.2590 -0.9455 0.0584 4.9914 4.7898 0.9817 3.4163 0.1899 0.2124 5.9579 1.4242</span> +<span class="r-out co"><span class="r-pr">#></span> 180: 93.0611 -6.2228 -2.0441 -4.2977 -0.9387 0.0320 4.0323 5.5685 0.9890 3.7202 0.1940 0.2335 6.2224 1.4194</span> +<span class="r-out co"><span class="r-pr">#></span> 181: 92.7741 -6.1462 -2.0477 -4.3335 -0.9454 0.1011 3.7007 5.1590 0.9807 3.8469 0.1939 0.2463 5.9703 1.4343</span> +<span class="r-out co"><span class="r-pr">#></span> 182: 93.0775 -6.0640 -2.0496 -4.3171 -0.9444 0.0897 5.0266 4.5597 0.9792 3.7741 0.1931 0.2186 5.6727 1.4858</span> +<span class="r-out co"><span class="r-pr">#></span> 183: 93.2566 -6.1757 -2.0368 -4.2888 -0.9560 0.0809 5.8284 5.2504 0.9636 3.7078 0.1939 0.2262 5.5170 1.4560</span> +<span class="r-out co"><span class="r-pr">#></span> 184: 93.0357 -6.1158 -2.0217 -4.3111 -0.9453 0.0901 6.7209 5.4048 0.9503 3.8949 0.1967 0.2209 5.3578 1.4704</span> +<span class="r-out co"><span class="r-pr">#></span> 185: 93.0173 -6.1998 -2.0371 -4.3713 -0.9451 0.0752 6.1040 5.8272 0.9333 4.4038 0.1951 0.2238 5.5896 1.4202</span> +<span class="r-out co"><span class="r-pr">#></span> 186: 93.2835 -6.1217 -2.0383 -4.3308 -0.9574 0.1110 6.0519 4.7669 0.9400 4.0265 0.1972 0.2274 5.4560 1.4602</span> +<span class="r-out co"><span class="r-pr">#></span> 187: 93.5312 -6.3356 -2.0253 -4.3418 -0.9583 0.1166 6.7561 5.8784 0.9346 4.0264 0.2038 0.2281 5.5024 1.4994</span> +<span class="r-out co"><span class="r-pr">#></span> 188: 93.6460 -5.8426 -2.0237 -4.4519 -0.9594 0.1283 6.3492 3.4189 0.9091 4.9358 0.2086 0.2348 5.4301 1.5893</span> +<span class="r-out co"><span class="r-pr">#></span> 189: 93.8538 -6.0183 -2.0178 -4.3911 -0.9797 0.1262 8.7939 3.7358 0.9008 4.4894 0.2125 0.2199 5.6613 1.5073</span> +<span class="r-out co"><span class="r-pr">#></span> 190: 93.1543 -6.1364 -2.0451 -4.4389 -0.9708 0.1584 9.9803 4.2747 0.8922 4.8507 0.2084 0.2607 5.9136 1.4572</span> +<span class="r-out co"><span class="r-pr">#></span> 191: 93.4334 -6.1466 -2.0389 -4.4661 -0.9678 0.1565 7.8390 4.4393 0.9022 4.7857 0.2105 0.2634 5.7161 1.5325</span> +<span class="r-out co"><span class="r-pr">#></span> 192: 93.3623 -6.0940 -2.0240 -4.4569 -0.9673 0.1420 8.0856 4.3185 0.8895 4.4721 0.2113 0.2350 5.5282 1.5221</span> +<span class="r-out co"><span class="r-pr">#></span> 193: 93.1990 -5.9864 -2.0301 -4.4538 -0.9563 0.1515 8.4425 3.7598 0.8814 4.4376 0.2013 0.2257 5.4205 1.4820</span> +<span class="r-out co"><span class="r-pr">#></span> 194: 93.3165 -6.0045 -2.0353 -4.4314 -0.9525 0.1486 8.2370 3.6742 0.8947 4.4594 0.1960 0.2248 5.4579 1.4767</span> +<span class="r-out co"><span class="r-pr">#></span> 195: 93.1288 -6.1006 -2.0551 -4.5184 -0.9503 0.1583 9.6259 4.2294 0.9040 5.1981 0.1950 0.1962 5.5602 1.4254</span> +<span class="r-out co"><span class="r-pr">#></span> 196: 93.1943 -5.9871 -2.0607 -4.4728 -0.9446 0.1482 9.3401 3.5579 0.8925 4.7901 0.1892 0.1879 5.7296 1.4172</span> +<span class="r-out co"><span class="r-pr">#></span> 197: 93.5803 -5.9131 -2.0522 -4.3675 -0.9476 0.1571 7.2599 3.4241 0.8857 3.8551 0.1886 0.1793 5.4832 1.6006</span> +<span class="r-out co"><span class="r-pr">#></span> 198: 93.5703 -5.9980 -2.0550 -4.3578 -0.9519 0.1491 7.0416 3.8805 0.8563 3.7930 0.1882 0.1896 5.4355 1.5402</span> +<span class="r-out co"><span class="r-pr">#></span> 199: 93.2909 -5.8288 -2.0532 -4.3605 -0.9518 0.1692 8.3926 3.0173 0.8566 3.8610 0.1902 0.2033 5.5735 1.5647</span> +<span class="r-out co"><span class="r-pr">#></span> 200: 93.4049 -5.7474 -2.0447 -4.3548 -0.9517 0.1812 7.4977 2.8256 0.8520 3.8236 0.1897 0.2060 5.5092 1.5699</span> +<span class="r-out co"><span class="r-pr">#></span> 201: 93.3386 -5.8209 -2.0398 -4.4174 -0.9597 0.1738 6.3555 3.0871 0.8431 4.3211 0.1853 0.2062 5.5460 1.5925</span> +<span class="r-out co"><span class="r-pr">#></span> 202: 93.3397 -5.8313 -2.0387 -4.4364 -0.9580 0.1669 6.0946 3.1018 0.8460 4.5093 0.1821 0.2068 5.6622 1.5740</span> +<span class="r-out co"><span class="r-pr">#></span> 203: 93.3071 -5.8276 -2.0384 -4.4758 -0.9571 0.1639 5.7815 3.0575 0.8608 4.9441 0.1826 0.2052 5.6855 1.5570</span> +<span class="r-out co"><span class="r-pr">#></span> 204: 93.3138 -5.8477 -2.0368 -4.4714 -0.9541 0.1658 5.7526 3.1322 0.8704 4.9129 0.1816 0.2057 5.6642 1.5606</span> +<span class="r-out co"><span class="r-pr">#></span> 205: 93.3066 -5.8537 -2.0395 -4.4842 -0.9521 0.1642 5.6045 3.1633 0.8748 5.0053 0.1805 0.2036 5.6633 1.5550</span> +<span class="r-out co"><span class="r-pr">#></span> 206: 93.3042 -5.8790 -2.0453 -4.4977 -0.9501 0.1633 5.7219 3.3320 0.8807 5.1121 0.1793 0.1999 5.6888 1.5413</span> +<span class="r-out co"><span class="r-pr">#></span> 207: 93.3281 -5.9005 -2.0504 -4.5109 -0.9480 0.1629 5.8004 3.4696 0.8865 5.2248 0.1789 0.1961 5.7206 1.5357</span> +<span class="r-out co"><span class="r-pr">#></span> 208: 93.3437 -5.8972 -2.0569 -4.5200 -0.9452 0.1641 5.7523 3.4604 0.8875 5.2848 0.1787 0.1933 5.7450 1.5288</span> +<span class="r-out co"><span class="r-pr">#></span> 209: 93.3265 -5.8864 -2.0628 -4.5092 -0.9440 0.1639 5.5355 3.4138 0.8882 5.1586 0.1791 0.1916 5.7744 1.5283</span> +<span class="r-out co"><span class="r-pr">#></span> 210: 93.3087 -5.8812 -2.0671 -4.5004 -0.9426 0.1677 5.3488 3.3975 0.8895 5.0589 0.1798 0.1924 5.7781 1.5307</span> +<span class="r-out co"><span class="r-pr">#></span> 211: 93.2807 -5.8760 -2.0703 -4.5009 -0.9413 0.1709 5.2654 3.3770 0.8894 5.0377 0.1805 0.1927 5.7808 1.5282</span> +<span class="r-out co"><span class="r-pr">#></span> 212: 93.2815 -5.8637 -2.0711 -4.4955 -0.9409 0.1708 5.3028 3.3250 0.8914 4.9702 0.1819 0.1941 5.7827 1.5274</span> +<span class="r-out co"><span class="r-pr">#></span> 213: 93.2828 -5.8481 -2.0709 -4.4895 -0.9396 0.1702 5.3840 3.2614 0.8913 4.9108 0.1826 0.1953 5.7744 1.5301</span> +<span class="r-out co"><span class="r-pr">#></span> 214: 93.2645 -5.8422 -2.0704 -4.4882 -0.9384 0.1710 5.3939 3.2358 0.8931 4.8944 0.1828 0.1955 5.7797 1.5351</span> +<span class="r-out co"><span class="r-pr">#></span> 215: 93.2591 -5.8519 -2.0709 -4.4858 -0.9380 0.1713 5.5142 3.2959 0.8953 4.8587 0.1822 0.1960 5.7853 1.5369</span> +<span class="r-out co"><span class="r-pr">#></span> 216: 93.2595 -5.8523 -2.0715 -4.4827 -0.9376 0.1723 5.5563 3.3077 0.8964 4.8306 0.1817 0.1973 5.7975 1.5396</span> +<span class="r-out co"><span class="r-pr">#></span> 217: 93.2503 -5.8512 -2.0732 -4.4737 -0.9373 0.1734 5.5036 3.3182 0.8959 4.7582 0.1817 0.1992 5.7940 1.5365</span> +<span class="r-out co"><span class="r-pr">#></span> 218: 93.2345 -5.8463 -2.0749 -4.4639 -0.9372 0.1747 5.5046 3.2959 0.8959 4.6771 0.1817 0.2008 5.7889 1.5340</span> +<span class="r-out co"><span class="r-pr">#></span> 219: 93.2264 -5.8439 -2.0757 -4.4549 -0.9364 0.1759 5.4970 3.2802 0.8966 4.6015 0.1819 0.2027 5.7804 1.5321</span> +<span class="r-out co"><span class="r-pr">#></span> 220: 93.2259 -5.8464 -2.0758 -4.4493 -0.9363 0.1771 5.4793 3.2944 0.8950 4.5498 0.1823 0.2049 5.7745 1.5344</span> +<span class="r-out co"><span class="r-pr">#></span> 221: 93.2243 -5.8505 -2.0768 -4.4443 -0.9367 0.1785 5.5360 3.3132 0.8924 4.5028 0.1829 0.2068 5.7556 1.5329</span> +<span class="r-out co"><span class="r-pr">#></span> 222: 93.2385 -5.8603 -2.0776 -4.4371 -0.9376 0.1800 5.5401 3.3878 0.8903 4.4416 0.1834 0.2096 5.7522 1.5317</span> +<span class="r-out co"><span class="r-pr">#></span> 223: 93.2339 -5.8634 -2.0780 -4.4309 -0.9377 0.1803 5.5522 3.4132 0.8882 4.3844 0.1838 0.2118 5.7457 1.5323</span> +<span class="r-out co"><span class="r-pr">#></span> 224: 93.2379 -5.8686 -2.0778 -4.4262 -0.9374 0.1803 5.5469 3.4421 0.8848 4.3375 0.1842 0.2137 5.7429 1.5323</span> +<span class="r-out co"><span class="r-pr">#></span> 225: 93.2329 -5.8654 -2.0784 -4.4222 -0.9373 0.1811 5.5553 3.4255 0.8843 4.2952 0.1848 0.2160 5.7452 1.5295</span> +<span class="r-out co"><span class="r-pr">#></span> 226: 93.2330 -5.8621 -2.0789 -4.4182 -0.9366 0.1816 5.5838 3.4123 0.8838 4.2565 0.1858 0.2176 5.7453 1.5284</span> +<span class="r-out co"><span class="r-pr">#></span> 227: 93.2309 -5.8549 -2.0794 -4.4153 -0.9365 0.1823 5.6720 3.3787 0.8827 4.2227 0.1866 0.2181 5.7339 1.5287</span> +<span class="r-out co"><span class="r-pr">#></span> 228: 93.2248 -5.8556 -2.0794 -4.4116 -0.9372 0.1832 5.7344 3.3780 0.8830 4.1863 0.1873 0.2200 5.7232 1.5308</span> +<span class="r-out co"><span class="r-pr">#></span> 229: 93.2215 -5.8615 -2.0798 -4.4081 -0.9373 0.1844 5.8478 3.4087 0.8821 4.1558 0.1878 0.2217 5.7174 1.5283</span> +<span class="r-out co"><span class="r-pr">#></span> 230: 93.2122 -5.8646 -2.0807 -4.4053 -0.9372 0.1858 5.8987 3.4233 0.8800 4.1288 0.1881 0.2233 5.7073 1.5272</span> +<span class="r-out co"><span class="r-pr">#></span> 231: 93.2080 -5.8665 -2.0816 -4.4025 -0.9372 0.1872 5.9544 3.4381 0.8782 4.1008 0.1883 0.2250 5.7006 1.5283</span> +<span class="r-out co"><span class="r-pr">#></span> 232: 93.1921 -5.8677 -2.0829 -4.3997 -0.9370 0.1887 5.9768 3.4440 0.8770 4.0748 0.1883 0.2268 5.7012 1.5261</span> +<span class="r-out co"><span class="r-pr">#></span> 233: 93.1794 -5.8674 -2.0840 -4.3972 -0.9363 0.1892 6.0074 3.4397 0.8757 4.0495 0.1884 0.2281 5.6997 1.5235</span> +<span class="r-out co"><span class="r-pr">#></span> 234: 93.1623 -5.8677 -2.0853 -4.3959 -0.9358 0.1898 5.9759 3.4442 0.8750 4.0330 0.1887 0.2295 5.7000 1.5223</span> +<span class="r-out co"><span class="r-pr">#></span> 235: 93.1499 -5.8709 -2.0862 -4.3918 -0.9356 0.1900 5.9951 3.4709 0.8747 4.0020 0.1891 0.2309 5.7002 1.5219</span> +<span class="r-out co"><span class="r-pr">#></span> 236: 93.1408 -5.8764 -2.0875 -4.3879 -0.9349 0.1898 6.0359 3.5027 0.8752 3.9720 0.1895 0.2321 5.7098 1.5196</span> +<span class="r-out co"><span class="r-pr">#></span> 237: 93.1307 -5.8766 -2.0887 -4.3843 -0.9344 0.1896 6.0589 3.5108 0.8755 3.9437 0.1900 0.2330 5.7176 1.5174</span> +<span class="r-out co"><span class="r-pr">#></span> 238: 93.1233 -5.8767 -2.0889 -4.3806 -0.9341 0.1891 6.0959 3.5158 0.8745 3.9173 0.1907 0.2339 5.7198 1.5169</span> +<span class="r-out co"><span class="r-pr">#></span> 239: 93.1245 -5.8810 -2.0889 -4.3775 -0.9337 0.1885 6.1196 3.5614 0.8746 3.8935 0.1915 0.2349 5.7177 1.5172</span> +<span class="r-out co"><span class="r-pr">#></span> 240: 93.1180 -5.8836 -2.0893 -4.3745 -0.9332 0.1883 6.1647 3.6004 0.8741 3.8709 0.1921 0.2360 5.7150 1.5192</span> +<span class="r-out co"><span class="r-pr">#></span> 241: 93.1096 -5.8838 -2.0898 -4.3714 -0.9327 0.1883 6.2283 3.6196 0.8743 3.8487 0.1927 0.2366 5.7177 1.5202</span> +<span class="r-out co"><span class="r-pr">#></span> 242: 93.1058 -5.8804 -2.0912 -4.3684 -0.9320 0.1888 6.2553 3.6018 0.8723 3.8274 0.1933 0.2378 5.7265 1.5198</span> +<span class="r-out co"><span class="r-pr">#></span> 243: 93.0953 -5.8762 -2.0924 -4.3668 -0.9315 0.1892 6.2692 3.5785 0.8705 3.8130 0.1940 0.2391 5.7353 1.5205</span> +<span class="r-out co"><span class="r-pr">#></span> 244: 93.0840 -5.8758 -2.0928 -4.3658 -0.9310 0.1889 6.2702 3.5746 0.8695 3.8007 0.1947 0.2401 5.7382 1.5205</span> +<span class="r-out co"><span class="r-pr">#></span> 245: 93.0720 -5.8795 -2.0933 -4.3647 -0.9306 0.1895 6.3022 3.5971 0.8685 3.7886 0.1953 0.2407 5.7367 1.5192</span> +<span class="r-out co"><span class="r-pr">#></span> 246: 93.0626 -5.8798 -2.0933 -4.3637 -0.9301 0.1898 6.2987 3.5992 0.8680 3.7781 0.1957 0.2410 5.7331 1.5184</span> +<span class="r-out co"><span class="r-pr">#></span> 247: 93.0526 -5.8805 -2.0934 -4.3610 -0.9298 0.1903 6.3067 3.6060 0.8682 3.7618 0.1963 0.2414 5.7329 1.5189</span> +<span class="r-out co"><span class="r-pr">#></span> 248: 93.0481 -5.8780 -2.0933 -4.3583 -0.9296 0.1911 6.3135 3.6007 0.8683 3.7460 0.1967 0.2420 5.7344 1.5191</span> +<span class="r-out co"><span class="r-pr">#></span> 249: 93.0483 -5.8762 -2.0933 -4.3558 -0.9294 0.1913 6.3095 3.5961 0.8685 3.7298 0.1970 0.2422 5.7414 1.5179</span> +<span class="r-out co"><span class="r-pr">#></span> 250: 93.0520 -5.8768 -2.0931 -4.3538 -0.9292 0.1912 6.2900 3.6003 0.8692 3.7176 0.1973 0.2424 5.7547 1.5148</span> +<span class="r-out co"><span class="r-pr">#></span> 251: 93.0430 -5.8769 -2.0930 -4.3516 -0.9291 0.1905 6.2815 3.6041 0.8704 3.7045 0.1975 0.2427 5.7653 1.5123</span> +<span class="r-out co"><span class="r-pr">#></span> 252: 93.0300 -5.8743 -2.0928 -4.3490 -0.9291 0.1901 6.2896 3.5885 0.8716 3.6919 0.1978 0.2428 5.7797 1.5106</span> +<span class="r-out co"><span class="r-pr">#></span> 253: 93.0217 -5.8740 -2.0926 -4.3468 -0.9289 0.1898 6.3238 3.5875 0.8731 3.6817 0.1981 0.2429 5.7885 1.5102</span> +<span class="r-out co"><span class="r-pr">#></span> 254: 93.0147 -5.8729 -2.0924 -4.3439 -0.9289 0.1892 6.3418 3.5857 0.8732 3.6683 0.1980 0.2426 5.7912 1.5102</span> +<span class="r-out co"><span class="r-pr">#></span> 255: 93.0144 -5.8743 -2.0922 -4.3407 -0.9290 0.1885 6.3755 3.5933 0.8735 3.6580 0.1979 0.2420 5.7932 1.5086</span> +<span class="r-out co"><span class="r-pr">#></span> 256: 93.0136 -5.8778 -2.0919 -4.3376 -0.9290 0.1876 6.3932 3.6240 0.8741 3.6481 0.1980 0.2418 5.7969 1.5066</span> +<span class="r-out co"><span class="r-pr">#></span> 257: 93.0116 -5.8792 -2.0917 -4.3345 -0.9291 0.1862 6.4096 3.6459 0.8744 3.6385 0.1980 0.2414 5.7990 1.5065</span> +<span class="r-out co"><span class="r-pr">#></span> 258: 93.0084 -5.8812 -2.0913 -4.3319 -0.9290 0.1842 6.4231 3.6686 0.8753 3.6281 0.1980 0.2414 5.8024 1.5050</span> +<span class="r-out co"><span class="r-pr">#></span> 259: 93.0090 -5.8866 -2.0909 -4.3293 -0.9287 0.1825 6.4361 3.7063 0.8762 3.6181 0.1981 0.2413 5.8106 1.5030</span> +<span class="r-out co"><span class="r-pr">#></span> 260: 93.0067 -5.8911 -2.0902 -4.3265 -0.9283 0.1811 6.4128 3.7384 0.8765 3.6076 0.1981 0.2412 5.8102 1.5026</span> +<span class="r-out co"><span class="r-pr">#></span> 261: 93.0060 -5.8933 -2.0894 -4.3237 -0.9284 0.1799 6.4253 3.7604 0.8765 3.5968 0.1981 0.2410 5.8080 1.5026</span> +<span class="r-out co"><span class="r-pr">#></span> 262: 93.0051 -5.8934 -2.0884 -4.3208 -0.9285 0.1789 6.4008 3.7597 0.8762 3.5855 0.1981 0.2412 5.8046 1.5020</span> +<span class="r-out co"><span class="r-pr">#></span> 263: 93.0019 -5.8945 -2.0875 -4.3182 -0.9287 0.1781 6.3788 3.7644 0.8758 3.5756 0.1982 0.2411 5.8048 1.5023</span> +<span class="r-out co"><span class="r-pr">#></span> 264: 93.0021 -5.8959 -2.0870 -4.3158 -0.9293 0.1773 6.3614 3.7682 0.8749 3.5667 0.1983 0.2410 5.8017 1.5021</span> +<span class="r-out co"><span class="r-pr">#></span> 265: 93.0053 -5.8989 -2.0866 -4.3130 -0.9296 0.1766 6.3506 3.7814 0.8739 3.5567 0.1982 0.2409 5.7995 1.5018</span> +<span class="r-out co"><span class="r-pr">#></span> 266: 93.0061 -5.8992 -2.0864 -4.3104 -0.9300 0.1757 6.3307 3.7730 0.8733 3.5471 0.1982 0.2408 5.7994 1.5012</span> +<span class="r-out co"><span class="r-pr">#></span> 267: 93.0098 -5.9009 -2.0861 -4.3077 -0.9302 0.1749 6.3326 3.7738 0.8730 3.5388 0.1983 0.2407 5.7964 1.5004</span> +<span class="r-out co"><span class="r-pr">#></span> 268: 93.0144 -5.9000 -2.0853 -4.3054 -0.9304 0.1740 6.3487 3.7623 0.8729 3.5290 0.1985 0.2405 5.7897 1.5014</span> +<span class="r-out co"><span class="r-pr">#></span> 269: 93.0146 -5.8984 -2.0847 -4.3032 -0.9306 0.1731 6.3716 3.7485 0.8735 3.5197 0.1985 0.2402 5.7867 1.5016</span> +<span class="r-out co"><span class="r-pr">#></span> 270: 93.0159 -5.8950 -2.0842 -4.3013 -0.9307 0.1722 6.3630 3.7266 0.8743 3.5098 0.1986 0.2400 5.7837 1.5016</span> +<span class="r-out co"><span class="r-pr">#></span> 271: 93.0161 -5.8925 -2.0837 -4.2995 -0.9309 0.1715 6.3539 3.7068 0.8744 3.5001 0.1986 0.2400 5.7843 1.5020</span> +<span class="r-out co"><span class="r-pr">#></span> 272: 93.0195 -5.8919 -2.0837 -4.2977 -0.9314 0.1710 6.3430 3.6964 0.8744 3.4922 0.1985 0.2400 5.7859 1.5031</span> +<span class="r-out co"><span class="r-pr">#></span> 273: 93.0184 -5.8923 -2.0837 -4.2961 -0.9318 0.1705 6.3531 3.6914 0.8743 3.4854 0.1984 0.2402 5.7880 1.5030</span> +<span class="r-out co"><span class="r-pr">#></span> 274: 93.0178 -5.8927 -2.0834 -4.2951 -0.9320 0.1701 6.3818 3.6865 0.8749 3.4824 0.1984 0.2403 5.7928 1.5020</span> +<span class="r-out co"><span class="r-pr">#></span> 275: 93.0204 -5.8937 -2.0833 -4.2942 -0.9324 0.1700 6.3961 3.6842 0.8754 3.4790 0.1984 0.2402 5.7949 1.5011</span> +<span class="r-out co"><span class="r-pr">#></span> 276: 93.0228 -5.8958 -2.0833 -4.2932 -0.9327 0.1699 6.3965 3.6870 0.8760 3.4752 0.1984 0.2402 5.7934 1.5002</span> +<span class="r-out co"><span class="r-pr">#></span> 277: 93.0251 -5.9000 -2.0833 -4.2921 -0.9329 0.1695 6.4076 3.7032 0.8766 3.4712 0.1985 0.2400 5.7979 1.4989</span> +<span class="r-out co"><span class="r-pr">#></span> 278: 93.0297 -5.9021 -2.0833 -4.2912 -0.9331 0.1690 6.4279 3.7073 0.8771 3.4671 0.1986 0.2399 5.7978 1.4981</span> +<span class="r-out co"><span class="r-pr">#></span> 279: 93.0273 -5.9021 -2.0832 -4.2902 -0.9332 0.1684 6.4349 3.7003 0.8779 3.4622 0.1988 0.2400 5.7993 1.4972</span> +<span class="r-out co"><span class="r-pr">#></span> 280: 93.0236 -5.9030 -2.0831 -4.2892 -0.9334 0.1674 6.4776 3.6986 0.8787 3.4576 0.1990 0.2401 5.8026 1.4963</span> +<span class="r-out co"><span class="r-pr">#></span> 281: 93.0172 -5.9037 -2.0829 -4.2881 -0.9337 0.1665 6.4942 3.6984 0.8797 3.4536 0.1992 0.2402 5.8056 1.4955</span> +<span class="r-out co"><span class="r-pr">#></span> 282: 93.0147 -5.9055 -2.0827 -4.2872 -0.9339 0.1656 6.4861 3.7031 0.8810 3.4492 0.1992 0.2403 5.8107 1.4954</span> +<span class="r-out co"><span class="r-pr">#></span> 283: 93.0138 -5.9053 -2.0824 -4.2865 -0.9341 0.1646 6.4962 3.6967 0.8822 3.4451 0.1993 0.2406 5.8142 1.4959</span> +<span class="r-out co"><span class="r-pr">#></span> 284: 93.0132 -5.9067 -2.0821 -4.2864 -0.9343 0.1636 6.5021 3.7013 0.8838 3.4437 0.1993 0.2406 5.8146 1.4955</span> +<span class="r-out co"><span class="r-pr">#></span> 285: 93.0138 -5.9081 -2.0819 -4.2859 -0.9343 0.1628 6.5037 3.7043 0.8851 3.4406 0.1994 0.2406 5.8146 1.4945</span> +<span class="r-out co"><span class="r-pr">#></span> 286: 93.0119 -5.9086 -2.0815 -4.2858 -0.9342 0.1620 6.5068 3.7037 0.8864 3.4395 0.1994 0.2404 5.8133 1.4936</span> +<span class="r-out co"><span class="r-pr">#></span> 287: 93.0122 -5.9089 -2.0813 -4.2860 -0.9342 0.1614 6.5202 3.7044 0.8872 3.4399 0.1997 0.2401 5.8096 1.4929</span> +<span class="r-out co"><span class="r-pr">#></span> 288: 93.0104 -5.9083 -2.0812 -4.2858 -0.9342 0.1609 6.5237 3.6997 0.8876 3.4376 0.1999 0.2398 5.8041 1.4924</span> +<span class="r-out co"><span class="r-pr">#></span> 289: 93.0076 -5.9066 -2.0812 -4.2854 -0.9342 0.1604 6.5121 3.6893 0.8881 3.4342 0.1999 0.2394 5.8021 1.4922</span> +<span class="r-out co"><span class="r-pr">#></span> 290: 93.0064 -5.9052 -2.0813 -4.2851 -0.9343 0.1602 6.5106 3.6772 0.8886 3.4309 0.2000 0.2389 5.7988 1.4915</span> +<span class="r-out co"><span class="r-pr">#></span> 291: 93.0071 -5.9031 -2.0813 -4.2849 -0.9345 0.1601 6.5031 3.6628 0.8891 3.4284 0.2000 0.2384 5.7959 1.4908</span> +<span class="r-out co"><span class="r-pr">#></span> 292: 93.0114 -5.9023 -2.0809 -4.2841 -0.9346 0.1594 6.4930 3.6538 0.8894 3.4237 0.2001 0.2383 5.7923 1.4902</span> +<span class="r-out co"><span class="r-pr">#></span> 293: 93.0148 -5.9032 -2.0807 -4.2834 -0.9348 0.1589 6.4836 3.6542 0.8898 3.4206 0.2002 0.2380 5.7893 1.4893</span> +<span class="r-out co"><span class="r-pr">#></span> 294: 93.0161 -5.9026 -2.0806 -4.2826 -0.9349 0.1582 6.4719 3.6469 0.8901 3.4176 0.2005 0.2375 5.7898 1.4886</span> +<span class="r-out co"><span class="r-pr">#></span> 295: 93.0212 -5.9008 -2.0806 -4.2817 -0.9350 0.1576 6.4649 3.6372 0.8904 3.4145 0.2007 0.2370 5.7885 1.4890</span> +<span class="r-out co"><span class="r-pr">#></span> 296: 93.0270 -5.8989 -2.0805 -4.2809 -0.9351 0.1569 6.4835 3.6279 0.8911 3.4124 0.2010 0.2366 5.7886 1.4884</span> +<span class="r-out co"><span class="r-pr">#></span> 297: 93.0291 -5.8969 -2.0803 -4.2800 -0.9352 0.1560 6.5014 3.6177 0.8915 3.4094 0.2012 0.2364 5.7873 1.4880</span> +<span class="r-out co"><span class="r-pr">#></span> 298: 93.0332 -5.8963 -2.0801 -4.2790 -0.9352 0.1551 6.5168 3.6111 0.8919 3.4065 0.2014 0.2361 5.7855 1.4875</span> +<span class="r-out co"><span class="r-pr">#></span> 299: 93.0339 -5.8961 -2.0799 -4.2782 -0.9352 0.1542 6.5288 3.6081 0.8927 3.4038 0.2015 0.2358 5.7844 1.4869</span> +<span class="r-out co"><span class="r-pr">#></span> 300: 93.0335 -5.8971 -2.0797 -4.2772 -0.9351 0.1533 6.5409 3.6097 0.8937 3.4009 0.2017 0.2356 5.7844 1.4859</span> +<span class="r-out co"><span class="r-pr">#></span> 301: 93.0320 -5.8979 -2.0796 -4.2762 -0.9350 0.1522 6.5553 3.6126 0.8945 3.3977 0.2020 0.2354 5.7898 1.4847</span> +<span class="r-out co"><span class="r-pr">#></span> 302: 93.0321 -5.8997 -2.0795 -4.2751 -0.9351 0.1513 6.5737 3.6195 0.8956 3.3943 0.2023 0.2351 5.7917 1.4835</span> +<span class="r-out co"><span class="r-pr">#></span> 303: 93.0328 -5.8984 -2.0792 -4.2739 -0.9351 0.1504 6.5888 3.6111 0.8964 3.3912 0.2025 0.2350 5.7915 1.4825</span> +<span class="r-out co"><span class="r-pr">#></span> 304: 93.0357 -5.8969 -2.0790 -4.2728 -0.9350 0.1494 6.5907 3.6018 0.8975 3.3882 0.2026 0.2348 5.7929 1.4813</span> +<span class="r-out co"><span class="r-pr">#></span> 305: 93.0351 -5.8953 -2.0786 -4.2718 -0.9349 0.1484 6.5764 3.5916 0.8986 3.3858 0.2027 0.2345 5.7937 1.4816</span> +<span class="r-out co"><span class="r-pr">#></span> 306: 93.0352 -5.8950 -2.0784 -4.2707 -0.9350 0.1475 6.5727 3.5890 0.8999 3.3835 0.2028 0.2341 5.7981 1.4810</span> +<span class="r-out co"><span class="r-pr">#></span> 307: 93.0354 -5.8947 -2.0784 -4.2699 -0.9351 0.1466 6.5759 3.5853 0.9010 3.3820 0.2030 0.2339 5.8028 1.4799</span> +<span class="r-out co"><span class="r-pr">#></span> 308: 93.0336 -5.8938 -2.0783 -4.2690 -0.9351 0.1459 6.5855 3.5776 0.9022 3.3809 0.2031 0.2333 5.8014 1.4788</span> +<span class="r-out co"><span class="r-pr">#></span> 309: 93.0311 -5.8931 -2.0780 -4.2683 -0.9351 0.1452 6.5799 3.5717 0.9038 3.3805 0.2033 0.2328 5.8048 1.4779</span> +<span class="r-out co"><span class="r-pr">#></span> 310: 93.0303 -5.8915 -2.0778 -4.2675 -0.9352 0.1447 6.5716 3.5609 0.9046 3.3797 0.2033 0.2323 5.8060 1.4774</span> +<span class="r-out co"><span class="r-pr">#></span> 311: 93.0275 -5.8915 -2.0776 -4.2668 -0.9352 0.1441 6.5679 3.5581 0.9052 3.3788 0.2034 0.2319 5.8056 1.4770</span> +<span class="r-out co"><span class="r-pr">#></span> 312: 93.0258 -5.8920 -2.0775 -4.2659 -0.9352 0.1435 6.5573 3.5571 0.9058 3.3775 0.2033 0.2314 5.8053 1.4766</span> +<span class="r-out co"><span class="r-pr">#></span> 313: 93.0234 -5.8928 -2.0773 -4.2649 -0.9353 0.1431 6.5510 3.5573 0.9065 3.3761 0.2033 0.2309 5.8046 1.4757</span> +<span class="r-out co"><span class="r-pr">#></span> 314: 93.0237 -5.8937 -2.0771 -4.2639 -0.9355 0.1425 6.5488 3.5578 0.9074 3.3747 0.2033 0.2303 5.8029 1.4751</span> +<span class="r-out co"><span class="r-pr">#></span> 315: 93.0237 -5.8940 -2.0769 -4.2629 -0.9357 0.1420 6.5480 3.5565 0.9081 3.3730 0.2034 0.2299 5.8010 1.4746</span> +<span class="r-out co"><span class="r-pr">#></span> 316: 93.0218 -5.8936 -2.0767 -4.2617 -0.9358 0.1413 6.5424 3.5517 0.9087 3.3705 0.2034 0.2296 5.7992 1.4741</span> +<span class="r-out co"><span class="r-pr">#></span> 317: 93.0218 -5.8932 -2.0766 -4.2606 -0.9359 0.1406 6.5576 3.5474 0.9091 3.3679 0.2034 0.2292 5.7965 1.4736</span> +<span class="r-out co"><span class="r-pr">#></span> 318: 93.0215 -5.8927 -2.0765 -4.2597 -0.9361 0.1402 6.5884 3.5420 0.9096 3.3661 0.2034 0.2288 5.7960 1.4727</span> +<span class="r-out co"><span class="r-pr">#></span> 319: 93.0201 -5.8938 -2.0764 -4.2588 -0.9361 0.1397 6.6095 3.5439 0.9101 3.3642 0.2034 0.2283 5.7943 1.4719</span> +<span class="r-out co"><span class="r-pr">#></span> 320: 93.0188 -5.8926 -2.0763 -4.2579 -0.9361 0.1392 6.6170 3.5368 0.9103 3.3622 0.2034 0.2282 5.7930 1.4711</span> +<span class="r-out co"><span class="r-pr">#></span> 321: 93.0155 -5.8908 -2.0762 -4.2569 -0.9361 0.1385 6.6328 3.5268 0.9105 3.3598 0.2033 0.2282 5.7921 1.4702</span> +<span class="r-out co"><span class="r-pr">#></span> 322: 93.0133 -5.8894 -2.0760 -4.2561 -0.9360 0.1378 6.6415 3.5192 0.9110 3.3580 0.2032 0.2282 5.7903 1.4698</span> +<span class="r-out co"><span class="r-pr">#></span> 323: 93.0089 -5.8888 -2.0759 -4.2555 -0.9360 0.1372 6.6480 3.5131 0.9107 3.3563 0.2031 0.2285 5.7915 1.4691</span> +<span class="r-out co"><span class="r-pr">#></span> 324: 93.0038 -5.8881 -2.0758 -4.2547 -0.9359 0.1364 6.6639 3.5076 0.9106 3.3547 0.2029 0.2287 5.7912 1.4687</span> +<span class="r-out co"><span class="r-pr">#></span> 325: 93.0011 -5.8871 -2.0756 -4.2540 -0.9359 0.1361 6.6587 3.5005 0.9102 3.3531 0.2028 0.2289 5.7896 1.4686</span> +<span class="r-out co"><span class="r-pr">#></span> 326: 93.0033 -5.8874 -2.0755 -4.2535 -0.9360 0.1360 6.6621 3.4995 0.9098 3.3510 0.2026 0.2294 5.7883 1.4686</span> +<span class="r-out co"><span class="r-pr">#></span> 327: 93.0039 -5.8885 -2.0754 -4.2532 -0.9361 0.1359 6.6589 3.5051 0.9093 3.3497 0.2025 0.2297 5.7869 1.4687</span> +<span class="r-out co"><span class="r-pr">#></span> 328: 93.0061 -5.8896 -2.0753 -4.2529 -0.9362 0.1355 6.6671 3.5132 0.9088 3.3484 0.2024 0.2299 5.7854 1.4687</span> +<span class="r-out co"><span class="r-pr">#></span> 329: 93.0077 -5.8915 -2.0755 -4.2525 -0.9363 0.1352 6.6719 3.5255 0.9085 3.3464 0.2024 0.2301 5.7850 1.4682</span> +<span class="r-out co"><span class="r-pr">#></span> 330: 93.0061 -5.8942 -2.0757 -4.2518 -0.9365 0.1351 6.6696 3.5399 0.9083 3.3438 0.2023 0.2302 5.7840 1.4680</span> +<span class="r-out co"><span class="r-pr">#></span> 331: 93.0032 -5.8953 -2.0759 -4.2513 -0.9366 0.1348 6.6554 3.5433 0.9080 3.3411 0.2022 0.2302 5.7839 1.4677</span> +<span class="r-out co"><span class="r-pr">#></span> 332: 93.0013 -5.8956 -2.0761 -4.2507 -0.9367 0.1347 6.6298 3.5423 0.9079 3.3385 0.2021 0.2302 5.7851 1.4672</span> +<span class="r-out co"><span class="r-pr">#></span> 333: 93.0026 -5.8950 -2.0764 -4.2502 -0.9368 0.1346 6.6207 3.5365 0.9078 3.3357 0.2021 0.2303 5.7849 1.4667</span> +<span class="r-out co"><span class="r-pr">#></span> 334: 93.0019 -5.8933 -2.0767 -4.2497 -0.9369 0.1348 6.6145 3.5259 0.9077 3.3330 0.2021 0.2302 5.7856 1.4662</span> +<span class="r-out co"><span class="r-pr">#></span> 335: 93.0038 -5.8930 -2.0768 -4.2492 -0.9370 0.1348 6.6200 3.5227 0.9078 3.3307 0.2020 0.2303 5.7845 1.4654</span> +<span class="r-out co"><span class="r-pr">#></span> 336: 93.0038 -5.8923 -2.0765 -4.2488 -0.9371 0.1348 6.6316 3.5180 0.9081 3.3291 0.2019 0.2304 5.7837 1.4654</span> +<span class="r-out co"><span class="r-pr">#></span> 337: 93.0074 -5.8927 -2.0764 -4.2485 -0.9373 0.1349 6.6509 3.5187 0.9083 3.3275 0.2018 0.2304 5.7808 1.4655</span> +<span class="r-out co"><span class="r-pr">#></span> 338: 93.0117 -5.8950 -2.0761 -4.2483 -0.9377 0.1349 6.6559 3.5291 0.9087 3.3263 0.2018 0.2303 5.7770 1.4657</span> +<span class="r-out co"><span class="r-pr">#></span> 339: 93.0172 -5.8960 -2.0759 -4.2482 -0.9380 0.1349 6.6610 3.5304 0.9090 3.3260 0.2017 0.2302 5.7744 1.4657</span> +<span class="r-out co"><span class="r-pr">#></span> 340: 93.0179 -5.8977 -2.0757 -4.2481 -0.9383 0.1349 6.6583 3.5340 0.9093 3.3263 0.2017 0.2301 5.7749 1.4650</span> +<span class="r-out co"><span class="r-pr">#></span> 341: 93.0201 -5.8986 -2.0755 -4.2484 -0.9386 0.1348 6.6603 3.5337 0.9092 3.3283 0.2018 0.2300 5.7738 1.4650</span> +<span class="r-out co"><span class="r-pr">#></span> 342: 93.0245 -5.8990 -2.0752 -4.2484 -0.9389 0.1348 6.6680 3.5324 0.9093 3.3297 0.2018 0.2300 5.7727 1.4649</span> +<span class="r-out co"><span class="r-pr">#></span> 343: 93.0302 -5.9006 -2.0751 -4.2484 -0.9391 0.1347 6.6715 3.5367 0.9093 3.3313 0.2017 0.2300 5.7729 1.4645</span> +<span class="r-out co"><span class="r-pr">#></span> 344: 93.0340 -5.9026 -2.0749 -4.2484 -0.9394 0.1346 6.6793 3.5438 0.9093 3.3326 0.2017 0.2301 5.7709 1.4646</span> +<span class="r-out co"><span class="r-pr">#></span> 345: 93.0372 -5.9049 -2.0746 -4.2484 -0.9397 0.1347 6.6874 3.5515 0.9090 3.3340 0.2017 0.2301 5.7688 1.4648</span> +<span class="r-out co"><span class="r-pr">#></span> 346: 93.0372 -5.9063 -2.0743 -4.2483 -0.9399 0.1348 6.6963 3.5592 0.9090 3.3348 0.2018 0.2299 5.7680 1.4656</span> +<span class="r-out co"><span class="r-pr">#></span> 347: 93.0383 -5.9075 -2.0742 -4.2481 -0.9402 0.1350 6.7101 3.5658 0.9093 3.3353 0.2018 0.2299 5.7672 1.4649</span> +<span class="r-out co"><span class="r-pr">#></span> 348: 93.0412 -5.9084 -2.0742 -4.2479 -0.9405 0.1351 6.7183 3.5707 0.9095 3.3356 0.2019 0.2297 5.7657 1.4645</span> +<span class="r-out co"><span class="r-pr">#></span> 349: 93.0436 -5.9097 -2.0742 -4.2477 -0.9407 0.1351 6.7143 3.5783 0.9098 3.3359 0.2019 0.2295 5.7646 1.4643</span> +<span class="r-out co"><span class="r-pr">#></span> 350: 93.0476 -5.9105 -2.0742 -4.2474 -0.9409 0.1351 6.7239 3.5808 0.9100 3.3354 0.2019 0.2294 5.7628 1.4639</span> +<span class="r-out co"><span class="r-pr">#></span> 351: 93.0506 -5.9113 -2.0741 -4.2473 -0.9411 0.1352 6.7270 3.5825 0.9103 3.3356 0.2019 0.2292 5.7604 1.4637</span> +<span class="r-out co"><span class="r-pr">#></span> 352: 93.0529 -5.9127 -2.0740 -4.2471 -0.9413 0.1353 6.7312 3.5886 0.9107 3.3358 0.2019 0.2290 5.7594 1.4634</span> +<span class="r-out co"><span class="r-pr">#></span> 353: 93.0580 -5.9139 -2.0739 -4.2470 -0.9415 0.1354 6.7315 3.5922 0.9111 3.3357 0.2019 0.2288 5.7571 1.4636</span> +<span class="r-out co"><span class="r-pr">#></span> 354: 93.0639 -5.9129 -2.0738 -4.2468 -0.9417 0.1354 6.7390 3.5876 0.9112 3.3356 0.2018 0.2286 5.7541 1.4642</span> +<span class="r-out co"><span class="r-pr">#></span> 355: 93.0671 -5.9131 -2.0737 -4.2467 -0.9417 0.1353 6.7348 3.5906 0.9113 3.3354 0.2017 0.2284 5.7520 1.4648</span> +<span class="r-out co"><span class="r-pr">#></span> 356: 93.0682 -5.9134 -2.0737 -4.2465 -0.9418 0.1352 6.7329 3.5962 0.9113 3.3353 0.2017 0.2283 5.7505 1.4649</span> +<span class="r-out co"><span class="r-pr">#></span> 357: 93.0698 -5.9128 -2.0738 -4.2471 -0.9418 0.1354 6.7397 3.5933 0.9115 3.3388 0.2016 0.2280 5.7512 1.4651</span> +<span class="r-out co"><span class="r-pr">#></span> 358: 93.0709 -5.9129 -2.0740 -4.2475 -0.9419 0.1355 6.7379 3.5915 0.9119 3.3416 0.2016 0.2278 5.7526 1.4644</span> +<span class="r-out co"><span class="r-pr">#></span> 359: 93.0718 -5.9128 -2.0742 -4.2478 -0.9419 0.1358 6.7428 3.5886 0.9123 3.3432 0.2015 0.2275 5.7516 1.4641</span> +<span class="r-out co"><span class="r-pr">#></span> 360: 93.0693 -5.9136 -2.0743 -4.2481 -0.9419 0.1360 6.7385 3.5930 0.9125 3.3443 0.2015 0.2272 5.7511 1.4636</span> +<span class="r-out co"><span class="r-pr">#></span> 361: 93.0674 -5.9148 -2.0744 -4.2484 -0.9419 0.1361 6.7230 3.6002 0.9127 3.3458 0.2015 0.2270 5.7514 1.4634</span> +<span class="r-out co"><span class="r-pr">#></span> 362: 93.0660 -5.9168 -2.0745 -4.2486 -0.9420 0.1361 6.7313 3.6117 0.9130 3.3473 0.2014 0.2270 5.7506 1.4636</span> +<span class="r-out co"><span class="r-pr">#></span> 363: 93.0635 -5.9196 -2.0746 -4.2490 -0.9421 0.1360 6.7388 3.6275 0.9132 3.3500 0.2014 0.2269 5.7493 1.4636</span> +<span class="r-out co"><span class="r-pr">#></span> 364: 93.0631 -5.9210 -2.0747 -4.2497 -0.9421 0.1361 6.7383 3.6323 0.9135 3.3548 0.2015 0.2268 5.7483 1.4634</span> +<span class="r-out co"><span class="r-pr">#></span> 365: 93.0635 -5.9219 -2.0747 -4.2504 -0.9421 0.1361 6.7402 3.6341 0.9137 3.3590 0.2015 0.2268 5.7461 1.4635</span> +<span class="r-out co"><span class="r-pr">#></span> 366: 93.0640 -5.9232 -2.0746 -4.2511 -0.9422 0.1362 6.7477 3.6409 0.9142 3.3624 0.2015 0.2267 5.7451 1.4641</span> +<span class="r-out co"><span class="r-pr">#></span> 367: 93.0616 -5.9247 -2.0746 -4.2518 -0.9422 0.1364 6.7557 3.6473 0.9148 3.3653 0.2015 0.2269 5.7472 1.4640</span> +<span class="r-out co"><span class="r-pr">#></span> 368: 93.0601 -5.9247 -2.0746 -4.2522 -0.9422 0.1366 6.7632 3.6452 0.9150 3.3678 0.2015 0.2270 5.7482 1.4639</span> +<span class="r-out co"><span class="r-pr">#></span> 369: 93.0583 -5.9240 -2.0748 -4.2527 -0.9423 0.1369 6.7737 3.6395 0.9148 3.3695 0.2015 0.2273 5.7499 1.4636</span> +<span class="r-out co"><span class="r-pr">#></span> 370: 93.0591 -5.9236 -2.0752 -4.2532 -0.9423 0.1373 6.7721 3.6352 0.9145 3.3718 0.2015 0.2276 5.7513 1.4636</span> +<span class="r-out co"><span class="r-pr">#></span> 371: 93.0607 -5.9235 -2.0755 -4.2540 -0.9424 0.1378 6.7682 3.6330 0.9143 3.3754 0.2015 0.2280 5.7535 1.4635</span> +<span class="r-out co"><span class="r-pr">#></span> 372: 93.0615 -5.9229 -2.0759 -4.2549 -0.9424 0.1382 6.7640 3.6288 0.9142 3.3795 0.2014 0.2284 5.7553 1.4633</span> +<span class="r-out co"><span class="r-pr">#></span> 373: 93.0612 -5.9237 -2.0763 -4.2557 -0.9424 0.1385 6.7641 3.6327 0.9140 3.3832 0.2012 0.2288 5.7570 1.4629</span> +<span class="r-out co"><span class="r-pr">#></span> 374: 93.0611 -5.9240 -2.0766 -4.2565 -0.9424 0.1389 6.7701 3.6341 0.9137 3.3872 0.2011 0.2293 5.7599 1.4625</span> +<span class="r-out co"><span class="r-pr">#></span> 375: 93.0615 -5.9247 -2.0770 -4.2573 -0.9424 0.1393 6.7729 3.6362 0.9134 3.3912 0.2009 0.2296 5.7629 1.4620</span> +<span class="r-out co"><span class="r-pr">#></span> 376: 93.0621 -5.9248 -2.0772 -4.2578 -0.9425 0.1397 6.7732 3.6371 0.9132 3.3931 0.2008 0.2298 5.7654 1.4613</span> +<span class="r-out co"><span class="r-pr">#></span> 377: 93.0622 -5.9255 -2.0774 -4.2582 -0.9426 0.1401 6.7681 3.6389 0.9130 3.3953 0.2007 0.2300 5.7678 1.4607</span> +<span class="r-out co"><span class="r-pr">#></span> 378: 93.0609 -5.9256 -2.0775 -4.2585 -0.9426 0.1402 6.7705 3.6381 0.9128 3.3972 0.2006 0.2301 5.7673 1.4602</span> +<span class="r-out co"><span class="r-pr">#></span> 379: 93.0590 -5.9262 -2.0776 -4.2589 -0.9426 0.1404 6.7777 3.6382 0.9127 3.3991 0.2005 0.2303 5.7668 1.4599</span> +<span class="r-out co"><span class="r-pr">#></span> 380: 93.0607 -5.9258 -2.0777 -4.2595 -0.9427 0.1407 6.7836 3.6350 0.9127 3.4031 0.2004 0.2305 5.7665 1.4598</span> +<span class="r-out co"><span class="r-pr">#></span> 381: 93.0617 -5.9251 -2.0777 -4.2596 -0.9427 0.1410 6.7880 3.6294 0.9125 3.4030 0.2003 0.2307 5.7651 1.4601</span> +<span class="r-out co"><span class="r-pr">#></span> 382: 93.0631 -5.9252 -2.0777 -4.2599 -0.9428 0.1413 6.7912 3.6278 0.9123 3.4038 0.2002 0.2310 5.7649 1.4606</span> +<span class="r-out co"><span class="r-pr">#></span> 383: 93.0621 -5.9253 -2.0778 -4.2602 -0.9429 0.1415 6.7834 3.6279 0.9119 3.4053 0.2000 0.2312 5.7657 1.4607</span> +<span class="r-out co"><span class="r-pr">#></span> 384: 93.0614 -5.9254 -2.0779 -4.2604 -0.9430 0.1416 6.7853 3.6280 0.9115 3.4066 0.1999 0.2313 5.7662 1.4608</span> +<span class="r-out co"><span class="r-pr">#></span> 385: 93.0613 -5.9259 -2.0780 -4.2605 -0.9430 0.1418 6.7757 3.6301 0.9112 3.4066 0.1997 0.2315 5.7678 1.4609</span> +<span class="r-out co"><span class="r-pr">#></span> 386: 93.0614 -5.9264 -2.0780 -4.2607 -0.9431 0.1418 6.7610 3.6331 0.9110 3.4073 0.1995 0.2317 5.7696 1.4612</span> +<span class="r-out co"><span class="r-pr">#></span> 387: 93.0631 -5.9276 -2.0780 -4.2610 -0.9432 0.1420 6.7595 3.6397 0.9108 3.4085 0.1993 0.2318 5.7716 1.4612</span> +<span class="r-out co"><span class="r-pr">#></span> 388: 93.0650 -5.9282 -2.0779 -4.2613 -0.9433 0.1421 6.7552 3.6445 0.9106 3.4092 0.1992 0.2318 5.7731 1.4612</span> +<span class="r-out co"><span class="r-pr">#></span> 389: 93.0644 -5.9286 -2.0779 -4.2616 -0.9434 0.1422 6.7488 3.6471 0.9104 3.4098 0.1991 0.2317 5.7724 1.4614</span> +<span class="r-out co"><span class="r-pr">#></span> 390: 93.0653 -5.9297 -2.0778 -4.2619 -0.9435 0.1423 6.7412 3.6524 0.9101 3.4103 0.1990 0.2317 5.7722 1.4615</span> +<span class="r-out co"><span class="r-pr">#></span> 391: 93.0647 -5.9297 -2.0778 -4.2623 -0.9435 0.1425 6.7508 3.6524 0.9101 3.4115 0.1989 0.2317 5.7729 1.4621</span> +<span class="r-out co"><span class="r-pr">#></span> 392: 93.0637 -5.9293 -2.0778 -4.2624 -0.9436 0.1427 6.7572 3.6498 0.9102 3.4109 0.1988 0.2317 5.7727 1.4623</span> +<span class="r-out co"><span class="r-pr">#></span> 393: 93.0657 -5.9294 -2.0778 -4.2632 -0.9436 0.1429 6.7607 3.6496 0.9104 3.4148 0.1987 0.2318 5.7719 1.4621</span> +<span class="r-out co"><span class="r-pr">#></span> 394: 93.0689 -5.9293 -2.0779 -4.2635 -0.9438 0.1431 6.7635 3.6489 0.9108 3.4141 0.1987 0.2318 5.7724 1.4623</span> +<span class="r-out co"><span class="r-pr">#></span> 395: 93.0705 -5.9295 -2.0780 -4.2640 -0.9438 0.1433 6.7753 3.6500 0.9110 3.4145 0.1986 0.2319 5.7724 1.4622</span> +<span class="r-out co"><span class="r-pr">#></span> 396: 93.0704 -5.9296 -2.0780 -4.2648 -0.9438 0.1435 6.7793 3.6511 0.9112 3.4175 0.1985 0.2319 5.7720 1.4618</span> +<span class="r-out co"><span class="r-pr">#></span> 397: 93.0715 -5.9302 -2.0781 -4.2656 -0.9438 0.1437 6.7782 3.6530 0.9114 3.4206 0.1985 0.2320 5.7706 1.4617</span> +<span class="r-out co"><span class="r-pr">#></span> 398: 93.0719 -5.9297 -2.0781 -4.2666 -0.9438 0.1439 6.7774 3.6510 0.9120 3.4258 0.1984 0.2319 5.7709 1.4616</span> +<span class="r-out co"><span class="r-pr">#></span> 399: 93.0720 -5.9296 -2.0781 -4.2678 -0.9438 0.1441 6.7819 3.6526 0.9126 3.4317 0.1984 0.2319 5.7717 1.4615</span> +<span class="r-out co"><span class="r-pr">#></span> 400: 93.0730 -5.9296 -2.0783 -4.2691 -0.9438 0.1443 6.7786 3.6538 0.9129 3.4389 0.1983 0.2319 5.7716 1.4614</span> +<span class="r-out co"><span class="r-pr">#></span> 401: 93.0728 -5.9292 -2.0783 -4.2706 -0.9437 0.1445 6.7731 3.6521 0.9133 3.4478 0.1982 0.2319 5.7701 1.4615</span> +<span class="r-out co"><span class="r-pr">#></span> 402: 93.0732 -5.9289 -2.0784 -4.2718 -0.9438 0.1447 6.7698 3.6517 0.9137 3.4542 0.1981 0.2319 5.7689 1.4618</span> +<span class="r-out co"><span class="r-pr">#></span> 403: 93.0732 -5.9301 -2.0785 -4.2730 -0.9438 0.1450 6.7640 3.6576 0.9142 3.4593 0.1980 0.2320 5.7693 1.4615</span> +<span class="r-out co"><span class="r-pr">#></span> 404: 93.0710 -5.9316 -2.0787 -4.2740 -0.9439 0.1453 6.7544 3.6647 0.9147 3.4644 0.1979 0.2320 5.7708 1.4611</span> +<span class="r-out co"><span class="r-pr">#></span> 405: 93.0687 -5.9322 -2.0788 -4.2750 -0.9440 0.1454 6.7547 3.6663 0.9153 3.4693 0.1978 0.2322 5.7714 1.4608</span> +<span class="r-out co"><span class="r-pr">#></span> 406: 93.0673 -5.9337 -2.0789 -4.2760 -0.9440 0.1456 6.7563 3.6726 0.9163 3.4742 0.1977 0.2324 5.7718 1.4603</span> +<span class="r-out co"><span class="r-pr">#></span> 407: 93.0653 -5.9345 -2.0791 -4.2769 -0.9440 0.1456 6.7601 3.6756 0.9169 3.4786 0.1976 0.2327 5.7732 1.4598</span> +<span class="r-out co"><span class="r-pr">#></span> 408: 93.0640 -5.9357 -2.0793 -4.2779 -0.9440 0.1455 6.7547 3.6821 0.9177 3.4838 0.1974 0.2329 5.7751 1.4592</span> +<span class="r-out co"><span class="r-pr">#></span> 409: 93.0646 -5.9371 -2.0795 -4.2784 -0.9440 0.1456 6.7486 3.6915 0.9184 3.4863 0.1973 0.2330 5.7766 1.4588</span> +<span class="r-out co"><span class="r-pr">#></span> 410: 93.0639 -5.9391 -2.0797 -4.2791 -0.9441 0.1457 6.7523 3.7048 0.9192 3.4889 0.1972 0.2329 5.7770 1.4582</span> +<span class="r-out co"><span class="r-pr">#></span> 411: 93.0628 -5.9401 -2.0799 -4.2799 -0.9442 0.1457 6.7529 3.7113 0.9199 3.4929 0.1972 0.2329 5.7761 1.4580</span> +<span class="r-out co"><span class="r-pr">#></span> 412: 93.0620 -5.9402 -2.0801 -4.2808 -0.9443 0.1458 6.7502 3.7099 0.9207 3.4972 0.1971 0.2328 5.7767 1.4577</span> +<span class="r-out co"><span class="r-pr">#></span> 413: 93.0628 -5.9403 -2.0804 -4.2816 -0.9443 0.1461 6.7466 3.7091 0.9214 3.5007 0.1970 0.2326 5.7771 1.4572</span> +<span class="r-out co"><span class="r-pr">#></span> 414: 93.0627 -5.9405 -2.0807 -4.2825 -0.9443 0.1463 6.7480 3.7089 0.9221 3.5048 0.1969 0.2325 5.7774 1.4567</span> +<span class="r-out co"><span class="r-pr">#></span> 415: 93.0614 -5.9402 -2.0810 -4.2836 -0.9443 0.1465 6.7474 3.7066 0.9226 3.5098 0.1969 0.2323 5.7780 1.4564</span> +<span class="r-out co"><span class="r-pr">#></span> 416: 93.0610 -5.9408 -2.0813 -4.2848 -0.9443 0.1469 6.7544 3.7116 0.9229 3.5157 0.1968 0.2321 5.7786 1.4559</span> +<span class="r-out co"><span class="r-pr">#></span> 417: 93.0601 -5.9413 -2.0815 -4.2860 -0.9443 0.1471 6.7592 3.7158 0.9234 3.5206 0.1967 0.2319 5.7793 1.4556</span> +<span class="r-out co"><span class="r-pr">#></span> 418: 93.0606 -5.9424 -2.0817 -4.2868 -0.9444 0.1473 6.7589 3.7214 0.9238 3.5237 0.1966 0.2318 5.7787 1.4553</span> +<span class="r-out co"><span class="r-pr">#></span> 419: 93.0605 -5.9433 -2.0818 -4.2877 -0.9444 0.1476 6.7641 3.7253 0.9242 3.5274 0.1965 0.2316 5.7780 1.4552</span> +<span class="r-out co"><span class="r-pr">#></span> 420: 93.0623 -5.9427 -2.0819 -4.2886 -0.9445 0.1478 6.7593 3.7216 0.9246 3.5310 0.1965 0.2314 5.7772 1.4551</span> +<span class="r-out co"><span class="r-pr">#></span> 421: 93.0630 -5.9418 -2.0819 -4.2895 -0.9445 0.1480 6.7489 3.7166 0.9250 3.5337 0.1964 0.2312 5.7764 1.4552</span> +<span class="r-out co"><span class="r-pr">#></span> 422: 93.0626 -5.9410 -2.0820 -4.2900 -0.9445 0.1482 6.7452 3.7124 0.9253 3.5350 0.1963 0.2311 5.7758 1.4549</span> +<span class="r-out co"><span class="r-pr">#></span> 423: 93.0629 -5.9407 -2.0822 -4.2906 -0.9446 0.1484 6.7409 3.7095 0.9256 3.5360 0.1963 0.2309 5.7753 1.4546</span> +<span class="r-out co"><span class="r-pr">#></span> 424: 93.0637 -5.9404 -2.0821 -4.2912 -0.9446 0.1485 6.7387 3.7073 0.9258 3.5370 0.1962 0.2308 5.7733 1.4546</span> +<span class="r-out co"><span class="r-pr">#></span> 425: 93.0625 -5.9402 -2.0821 -4.2917 -0.9447 0.1486 6.7330 3.7061 0.9258 3.5381 0.1961 0.2306 5.7722 1.4548</span> +<span class="r-out co"><span class="r-pr">#></span> 426: 93.0624 -5.9399 -2.0820 -4.2921 -0.9447 0.1487 6.7256 3.7034 0.9259 3.5387 0.1961 0.2304 5.7719 1.4545</span> +<span class="r-out co"><span class="r-pr">#></span> 427: 93.0606 -5.9397 -2.0821 -4.2925 -0.9447 0.1488 6.7139 3.7010 0.9257 3.5394 0.1961 0.2301 5.7730 1.4545</span> +<span class="r-out co"><span class="r-pr">#></span> 428: 93.0601 -5.9394 -2.0822 -4.2929 -0.9447 0.1489 6.7062 3.6984 0.9256 3.5405 0.1961 0.2298 5.7723 1.4543</span> +<span class="r-out co"><span class="r-pr">#></span> 429: 93.0615 -5.9391 -2.0821 -4.2933 -0.9447 0.1490 6.7040 3.6956 0.9254 3.5412 0.1960 0.2297 5.7714 1.4544</span> +<span class="r-out co"><span class="r-pr">#></span> 430: 93.0654 -5.9389 -2.0820 -4.2934 -0.9448 0.1491 6.7016 3.6934 0.9253 3.5412 0.1960 0.2295 5.7710 1.4546</span> +<span class="r-out co"><span class="r-pr">#></span> 431: 93.0674 -5.9392 -2.0819 -4.2936 -0.9449 0.1491 6.6946 3.6935 0.9252 3.5414 0.1960 0.2294 5.7699 1.4547</span> +<span class="r-out co"><span class="r-pr">#></span> 432: 93.0683 -5.9401 -2.0818 -4.2938 -0.9450 0.1491 6.6895 3.6960 0.9250 3.5417 0.1961 0.2292 5.7687 1.4549</span> +<span class="r-out co"><span class="r-pr">#></span> 433: 93.0693 -5.9411 -2.0815 -4.2942 -0.9451 0.1491 6.6826 3.7003 0.9254 3.5433 0.1961 0.2291 5.7679 1.4549</span> +<span class="r-out co"><span class="r-pr">#></span> 434: 93.0720 -5.9410 -2.0813 -4.2945 -0.9452 0.1491 6.6842 3.6998 0.9258 3.5440 0.1960 0.2290 5.7662 1.4548</span> +<span class="r-out co"><span class="r-pr">#></span> 435: 93.0735 -5.9417 -2.0811 -4.2947 -0.9453 0.1490 6.6907 3.7029 0.9261 3.5446 0.1960 0.2290 5.7651 1.4548</span> +<span class="r-out co"><span class="r-pr">#></span> 436: 93.0752 -5.9430 -2.0809 -4.2949 -0.9454 0.1489 6.6939 3.7083 0.9266 3.5459 0.1959 0.2290 5.7638 1.4547</span> +<span class="r-out co"><span class="r-pr">#></span> 437: 93.0774 -5.9442 -2.0807 -4.2952 -0.9455 0.1487 6.7016 3.7147 0.9270 3.5474 0.1960 0.2290 5.7624 1.4550</span> +<span class="r-out co"><span class="r-pr">#></span> 438: 93.0795 -5.9453 -2.0805 -4.2954 -0.9456 0.1485 6.7089 3.7212 0.9275 3.5491 0.1959 0.2291 5.7614 1.4551</span> +<span class="r-out co"><span class="r-pr">#></span> 439: 93.0816 -5.9467 -2.0802 -4.2956 -0.9457 0.1484 6.7230 3.7291 0.9281 3.5503 0.1959 0.2293 5.7616 1.4551</span> +<span class="r-out co"><span class="r-pr">#></span> 440: 93.0834 -5.9475 -2.0800 -4.2957 -0.9458 0.1480 6.7306 3.7340 0.9287 3.5512 0.1960 0.2295 5.7631 1.4551</span> +<span class="r-out co"><span class="r-pr">#></span> 441: 93.0855 -5.9480 -2.0797 -4.2961 -0.9459 0.1478 6.7436 3.7373 0.9292 3.5534 0.1960 0.2299 5.7642 1.4553</span> +<span class="r-out co"><span class="r-pr">#></span> 442: 93.0885 -5.9488 -2.0793 -4.2963 -0.9460 0.1474 6.7533 3.7419 0.9297 3.5546 0.1960 0.2304 5.7630 1.4554</span> +<span class="r-out co"><span class="r-pr">#></span> 443: 93.0907 -5.9497 -2.0789 -4.2967 -0.9461 0.1471 6.7641 3.7469 0.9304 3.5570 0.1960 0.2308 5.7616 1.4554</span> +<span class="r-out co"><span class="r-pr">#></span> 444: 93.0905 -5.9504 -2.0785 -4.2972 -0.9462 0.1467 6.7570 3.7486 0.9312 3.5601 0.1960 0.2311 5.7604 1.4553</span> +<span class="r-out co"><span class="r-pr">#></span> 445: 93.0903 -5.9515 -2.0782 -4.2977 -0.9462 0.1462 6.7547 3.7543 0.9319 3.5635 0.1960 0.2314 5.7595 1.4550</span> +<span class="r-out co"><span class="r-pr">#></span> 446: 93.0902 -5.9530 -2.0778 -4.2982 -0.9462 0.1459 6.7562 3.7615 0.9325 3.5664 0.1960 0.2316 5.7580 1.4548</span> +<span class="r-out co"><span class="r-pr">#></span> 447: 93.0905 -5.9541 -2.0775 -4.2990 -0.9463 0.1455 6.7639 3.7668 0.9333 3.5719 0.1960 0.2318 5.7574 1.4543</span> +<span class="r-out co"><span class="r-pr">#></span> 448: 93.0912 -5.9555 -2.0772 -4.2999 -0.9463 0.1452 6.7671 3.7736 0.9340 3.5783 0.1960 0.2322 5.7572 1.4540</span> +<span class="r-out co"><span class="r-pr">#></span> 449: 93.0918 -5.9570 -2.0769 -4.3004 -0.9464 0.1448 6.7824 3.7802 0.9345 3.5809 0.1960 0.2326 5.7561 1.4537</span> +<span class="r-out co"><span class="r-pr">#></span> 450: 93.0901 -5.9579 -2.0766 -4.3011 -0.9464 0.1444 6.7866 3.7829 0.9351 3.5853 0.1959 0.2329 5.7551 1.4536</span> +<span class="r-out co"><span class="r-pr">#></span> 451: 93.0899 -5.9594 -2.0763 -4.3016 -0.9465 0.1439 6.7875 3.7896 0.9356 3.5888 0.1959 0.2332 5.7550 1.4537</span> +<span class="r-out co"><span class="r-pr">#></span> 452: 93.0902 -5.9603 -2.0759 -4.3023 -0.9465 0.1435 6.7953 3.7926 0.9363 3.5927 0.1958 0.2335 5.7537 1.4538</span> +<span class="r-out co"><span class="r-pr">#></span> 453: 93.0906 -5.9615 -2.0755 -4.3026 -0.9465 0.1430 6.7996 3.7982 0.9372 3.5950 0.1958 0.2338 5.7531 1.4539</span> +<span class="r-out co"><span class="r-pr">#></span> 454: 93.0909 -5.9614 -2.0751 -4.3029 -0.9465 0.1425 6.8016 3.7969 0.9381 3.5976 0.1958 0.2340 5.7532 1.4540</span> +<span class="r-out co"><span class="r-pr">#></span> 455: 93.0909 -5.9610 -2.0749 -4.3035 -0.9464 0.1420 6.8022 3.7940 0.9391 3.6022 0.1957 0.2342 5.7532 1.4539</span> +<span class="r-out co"><span class="r-pr">#></span> 456: 93.0916 -5.9600 -2.0746 -4.3045 -0.9463 0.1416 6.7942 3.7893 0.9398 3.6104 0.1957 0.2344 5.7540 1.4537</span> +<span class="r-out co"><span class="r-pr">#></span> 457: 93.0905 -5.9595 -2.0744 -4.3058 -0.9463 0.1411 6.7931 3.7866 0.9407 3.6210 0.1956 0.2345 5.7551 1.4534</span> +<span class="r-out co"><span class="r-pr">#></span> 458: 93.0905 -5.9597 -2.0742 -4.3071 -0.9462 0.1407 6.7877 3.7882 0.9416 3.6327 0.1955 0.2347 5.7566 1.4532</span> +<span class="r-out co"><span class="r-pr">#></span> 459: 93.0895 -5.9598 -2.0741 -4.3078 -0.9461 0.1402 6.7884 3.7889 0.9425 3.6383 0.1955 0.2349 5.7601 1.4527</span> +<span class="r-out co"><span class="r-pr">#></span> 460: 93.0871 -5.9602 -2.0741 -4.3086 -0.9460 0.1398 6.7889 3.7912 0.9434 3.6439 0.1954 0.2350 5.7619 1.4522</span> +<span class="r-out co"><span class="r-pr">#></span> 461: 93.0854 -5.9613 -2.0739 -4.3091 -0.9459 0.1393 6.7813 3.7973 0.9440 3.6481 0.1953 0.2351 5.7620 1.4520</span> +<span class="r-out co"><span class="r-pr">#></span> 462: 93.0838 -5.9623 -2.0737 -4.3093 -0.9458 0.1388 6.7791 3.8037 0.9445 3.6498 0.1953 0.2353 5.7616 1.4518</span> +<span class="r-out co"><span class="r-pr">#></span> 463: 93.0816 -5.9629 -2.0734 -4.3095 -0.9457 0.1384 6.7733 3.8070 0.9451 3.6508 0.1952 0.2355 5.7626 1.4519</span> +<span class="r-out co"><span class="r-pr">#></span> 464: 93.0792 -5.9631 -2.0731 -4.3095 -0.9457 0.1379 6.7697 3.8081 0.9460 3.6507 0.1951 0.2358 5.7638 1.4518</span> +<span class="r-out co"><span class="r-pr">#></span> 465: 93.0775 -5.9633 -2.0728 -4.3095 -0.9456 0.1374 6.7717 3.8095 0.9466 3.6506 0.1950 0.2361 5.7647 1.4519</span> +<span class="r-out co"><span class="r-pr">#></span> 466: 93.0774 -5.9640 -2.0725 -4.3097 -0.9455 0.1368 6.7686 3.8141 0.9473 3.6516 0.1949 0.2363 5.7662 1.4516</span> +<span class="r-out co"><span class="r-pr">#></span> 467: 93.0773 -5.9646 -2.0722 -4.3100 -0.9454 0.1364 6.7668 3.8172 0.9480 3.6535 0.1948 0.2366 5.7671 1.4516</span> +<span class="r-out co"><span class="r-pr">#></span> 468: 93.0777 -5.9653 -2.0719 -4.3106 -0.9453 0.1358 6.7648 3.8226 0.9487 3.6566 0.1947 0.2371 5.7681 1.4514</span> +<span class="r-out co"><span class="r-pr">#></span> 469: 93.0778 -5.9657 -2.0717 -4.3112 -0.9453 0.1353 6.7617 3.8253 0.9495 3.6588 0.1947 0.2375 5.7686 1.4510</span> +<span class="r-out co"><span class="r-pr">#></span> 470: 93.0769 -5.9663 -2.0715 -4.3117 -0.9452 0.1347 6.7650 3.8278 0.9503 3.6613 0.1947 0.2379 5.7688 1.4506</span> +<span class="r-out co"><span class="r-pr">#></span> 471: 93.0749 -5.9664 -2.0714 -4.3123 -0.9451 0.1342 6.7708 3.8280 0.9510 3.6643 0.1947 0.2383 5.7699 1.4505</span> +<span class="r-out co"><span class="r-pr">#></span> 472: 93.0721 -5.9668 -2.0713 -4.3127 -0.9450 0.1337 6.7756 3.8284 0.9517 3.6665 0.1947 0.2386 5.7710 1.4501</span> +<span class="r-out co"><span class="r-pr">#></span> 473: 93.0696 -5.9670 -2.0713 -4.3133 -0.9449 0.1333 6.7784 3.8280 0.9522 3.6698 0.1947 0.2388 5.7716 1.4498</span> +<span class="r-out co"><span class="r-pr">#></span> 474: 93.0674 -5.9673 -2.0714 -4.3138 -0.9448 0.1329 6.7761 3.8281 0.9527 3.6731 0.1947 0.2390 5.7729 1.4496</span> +<span class="r-out co"><span class="r-pr">#></span> 475: 93.0655 -5.9679 -2.0714 -4.3143 -0.9447 0.1324 6.7779 3.8302 0.9531 3.6762 0.1947 0.2391 5.7743 1.4493</span> +<span class="r-out co"><span class="r-pr">#></span> 476: 93.0643 -5.9682 -2.0713 -4.3144 -0.9447 0.1321 6.7776 3.8314 0.9536 3.6768 0.1946 0.2391 5.7762 1.4492</span> +<span class="r-out co"><span class="r-pr">#></span> 477: 93.0631 -5.9684 -2.0714 -4.3146 -0.9446 0.1317 6.7725 3.8326 0.9540 3.6787 0.1945 0.2392 5.7768 1.4492</span> +<span class="r-out co"><span class="r-pr">#></span> 478: 93.0630 -5.9693 -2.0715 -4.3148 -0.9447 0.1314 6.7626 3.8365 0.9543 3.6788 0.1944 0.2395 5.7785 1.4492</span> +<span class="r-out co"><span class="r-pr">#></span> 479: 93.0634 -5.9710 -2.0714 -4.3148 -0.9447 0.1310 6.7499 3.8462 0.9547 3.6778 0.1943 0.2399 5.7798 1.4490</span> +<span class="r-out co"><span class="r-pr">#></span> 480: 93.0651 -5.9732 -2.0715 -4.3147 -0.9447 0.1307 6.7463 3.8616 0.9548 3.6770 0.1943 0.2403 5.7810 1.4488</span> +<span class="r-out co"><span class="r-pr">#></span> 481: 93.0664 -5.9747 -2.0715 -4.3149 -0.9447 0.1304 6.7442 3.8722 0.9550 3.6780 0.1941 0.2409 5.7811 1.4487</span> +<span class="r-out co"><span class="r-pr">#></span> 482: 93.0647 -5.9762 -2.0714 -4.3151 -0.9447 0.1300 6.7389 3.8834 0.9554 3.6784 0.1941 0.2414 5.7816 1.4484</span> +<span class="r-out co"><span class="r-pr">#></span> 483: 93.0628 -5.9778 -2.0714 -4.3153 -0.9447 0.1295 6.7352 3.8943 0.9557 3.6783 0.1940 0.2419 5.7820 1.4483</span> +<span class="r-out co"><span class="r-pr">#></span> 484: 93.0614 -5.9787 -2.0715 -4.3153 -0.9447 0.1291 6.7314 3.8999 0.9559 3.6774 0.1939 0.2424 5.7819 1.4481</span> +<span class="r-out co"><span class="r-pr">#></span> 485: 93.0593 -5.9789 -2.0715 -4.3153 -0.9447 0.1288 6.7293 3.9007 0.9561 3.6765 0.1938 0.2430 5.7815 1.4480</span> +<span class="r-out co"><span class="r-pr">#></span> 486: 93.0575 -5.9793 -2.0716 -4.3152 -0.9447 0.1284 6.7331 3.9021 0.9563 3.6753 0.1938 0.2434 5.7806 1.4480</span> +<span class="r-out co"><span class="r-pr">#></span> 487: 93.0555 -5.9796 -2.0716 -4.3152 -0.9447 0.1281 6.7342 3.9036 0.9566 3.6741 0.1937 0.2439 5.7805 1.4479</span> +<span class="r-out co"><span class="r-pr">#></span> 488: 93.0545 -5.9795 -2.0716 -4.3152 -0.9447 0.1277 6.7365 3.9024 0.9569 3.6729 0.1937 0.2444 5.7795 1.4480</span> +<span class="r-out co"><span class="r-pr">#></span> 489: 93.0550 -5.9800 -2.0716 -4.3152 -0.9447 0.1274 6.7336 3.9046 0.9571 3.6719 0.1937 0.2448 5.7778 1.4481</span> +<span class="r-out co"><span class="r-pr">#></span> 490: 93.0571 -5.9793 -2.0715 -4.3152 -0.9447 0.1272 6.7331 3.9009 0.9573 3.6704 0.1936 0.2450 5.7767 1.4484</span> +<span class="r-out co"><span class="r-pr">#></span> 491: 93.0584 -5.9787 -2.0714 -4.3151 -0.9447 0.1270 6.7280 3.8980 0.9575 3.6688 0.1936 0.2452 5.7764 1.4487</span> +<span class="r-out co"><span class="r-pr">#></span> 492: 93.0589 -5.9786 -2.0714 -4.3150 -0.9447 0.1267 6.7264 3.8971 0.9578 3.6675 0.1936 0.2455 5.7759 1.4489</span> +<span class="r-out co"><span class="r-pr">#></span> 493: 93.0593 -5.9790 -2.0711 -4.3149 -0.9447 0.1265 6.7273 3.8982 0.9584 3.6660 0.1935 0.2456 5.7759 1.4490</span> +<span class="r-out co"><span class="r-pr">#></span> 494: 93.0594 -5.9805 -2.0710 -4.3149 -0.9448 0.1263 6.7291 3.9066 0.9590 3.6650 0.1935 0.2457 5.7758 1.4489</span> +<span class="r-out co"><span class="r-pr">#></span> 495: 93.0596 -5.9816 -2.0709 -4.3148 -0.9448 0.1261 6.7281 3.9123 0.9593 3.6639 0.1936 0.2459 5.7745 1.4490</span> +<span class="r-out co"><span class="r-pr">#></span> 496: 93.0590 -5.9829 -2.0707 -4.3148 -0.9448 0.1259 6.7319 3.9227 0.9597 3.6628 0.1936 0.2461 5.7740 1.4491</span> +<span class="r-out co"><span class="r-pr">#></span> 497: 93.0580 -5.9842 -2.0706 -4.3148 -0.9448 0.1257 6.7388 3.9326 0.9600 3.6623 0.1936 0.2463 5.7732 1.4492</span> +<span class="r-out co"><span class="r-pr">#></span> 498: 93.0578 -5.9848 -2.0705 -4.3148 -0.9448 0.1255 6.7447 3.9368 0.9605 3.6618 0.1936 0.2464 5.7726 1.4494</span> +<span class="r-out co"><span class="r-pr">#></span> 499: 93.0568 -5.9843 -2.0704 -4.3147 -0.9447 0.1253 6.7475 3.9341 0.9609 3.6612 0.1937 0.2467 5.7718 1.4495</span> +<span class="r-out co"><span class="r-pr">#></span> 500: 93.0563 -5.9831 -2.0703 -4.3147 -0.9447 0.1251 6.7500 3.9292 0.9614 3.6607 0.1937 0.2469 5.7712 1.4496</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-in"><span class="va">f_nlmixr_dfop_sfo_focei_obs</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_obs</span><span class="op">[</span><span class="st">"DFOP-SFO"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"focei"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="font-weight: bold;">Key:</span> U: Unscaled Parameters; X: Back-transformed parameters; G: Gill difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> F: Forward difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> C: Central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> M: Mixed forward and central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> Unscaled parameters for Omegas=chol(solve(omega));</span> +<span class="r-out co"><span class="r-pr">#></span> Diagonals are transformed, as specified by foceiControl(diagXform=)</span> +<span class="r-out co"><span class="r-pr">#></span> |-----+---------------+-----------+-----------+-----------+-----------|</span> +<span class="r-out co"><span class="r-pr">#></span> | #| Objective Fun | parent_0 | log_k_A1 |f_parent_qlogis | log_k1 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| log_k2 | g_qlogis |sigma_parent | sigma_A1 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| o1 | o2 | o3 | o4 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| o5 | o6 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 1</span>| 488.98943 | 1.000 | -1.000 | -0.9115 | -0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9817 | -0.8883 | -0.8515 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8775 | -0.8743 | -0.8683 | -0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8746 | -0.8685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 488.98943 | 93.00 | -5.300 | -0.9500 | -2.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.400 | 0.1900 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 488.98943</span> | 93.00 | 0.004992 | 0.2789 | 0.1353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01228 | 0.5474 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | G| Gill Diff. | -27.68 | 2.403 | -0.1248 | -0.3242 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3705 | 0.07384 | -31.92 | -15.13 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 14.74 | 13.03 | -12.01 | -2.072 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 5.553 | -10.09 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 2</span>| 1205.4696 | 1.534 | -1.046 | -0.9091 | -0.9266 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9745 | -0.8897 | -0.2358 | -0.5780 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.162 | -1.126 | -0.6367 | -0.8323 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.9817 | -0.6738 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 1205.4696 | 142.6 | -5.346 | -0.9477 | -1.994 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.393 | 0.1897 | 2.616 | 1.260 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.5160 | 0.6557 | 1.444 | 1.015 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7709 | 1.387 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 1205.4696</span> | 142.6 | 0.004766 | 0.2793 | 0.1362 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01237 | 0.5473 | 2.616 | 1.260 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.5160 | 0.6557 | 1.444 | 1.015 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7709 | 1.387 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 3</span>| 510.70816 | 1.053 | -1.005 | -0.9113 | -0.9322 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9810 | -0.8884 | -0.7899 | -0.8406 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9059 | -0.8995 | -0.8452 | -0.8683 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8853 | -0.8491 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 510.70816 | 97.96 | -5.305 | -0.9498 | -1.999 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.399 | 0.1900 | 2.062 | 1.116 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7005 | 0.8538 | 1.199 | 0.9804 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8541 | 1.184 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 510.70816</span> | 97.96 | 0.004969 | 0.2789 | 0.1354 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01229 | 0.5474 | 2.062 | 1.116 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7005 | 0.8538 | 1.199 | 0.9804 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8541 | 1.184 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 4</span>| 494.11470 | 1.005 | -1.000 | -0.9115 | -0.9328 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9816 | -0.8883 | -0.8453 | -0.8669 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8803 | -0.8769 | -0.8660 | -0.8719 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8757 | -0.8666 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.1147 | 93.50 | -5.300 | -0.9500 | -2.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.400 | 0.1900 | 2.006 | 1.102 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7190 | 0.8736 | 1.175 | 0.9768 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8624 | 1.163 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.1147</span> | 93.50 | 0.004989 | 0.2789 | 0.1353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01228 | 0.5474 | 2.006 | 1.102 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7190 | 0.8736 | 1.175 | 0.9768 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8624 | 1.163 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 5</span>| 494.35784 | 1.001 | -1.000 | -0.9115 | -0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9817 | -0.8883 | -0.8509 | -0.8695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8778 | -0.8746 | -0.8681 | -0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8747 | -0.8683 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.35784 | 93.05 | -5.300 | -0.9500 | -2.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.400 | 0.1900 | 2.001 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7208 | 0.8755 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8632 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.35784</span> | 93.05 | 0.004991 | 0.2789 | 0.1353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01228 | 0.5474 | 2.001 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7208 | 0.8755 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8632 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 6</span>| 494.40319 | 1.000 | -1.000 | -0.9115 | -0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9817 | -0.8883 | -0.8514 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8775 | -0.8744 | -0.8683 | -0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8746 | -0.8685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.40319 | 93.00 | -5.300 | -0.9500 | -2.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.400 | 0.1900 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8757 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.40319</span> | 93.00 | 0.004992 | 0.2789 | 0.1353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01228 | 0.5474 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8757 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 7</span>| 494.40793 | 1.000 | -1.000 | -0.9115 | -0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9817 | -0.8883 | -0.8515 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8775 | -0.8744 | -0.8683 | -0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8746 | -0.8685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.40793 | 93.00 | -5.300 | -0.9500 | -2.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.400 | 0.1900 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.40793</span> | 93.00 | 0.004992 | 0.2789 | 0.1353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01228 | 0.5474 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 8</span>| 494.40830 | 1.000 | -1.000 | -0.9115 | -0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9817 | -0.8883 | -0.8515 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8775 | -0.8743 | -0.8683 | -0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8746 | -0.8685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.4083 | 93.00 | -5.300 | -0.9500 | -2.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.400 | 0.1900 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.4083</span> | 93.00 | 0.004992 | 0.2789 | 0.1353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01228 | 0.5474 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 9</span>| 494.40832 | 1.000 | -1.000 | -0.9115 | -0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9817 | -0.8883 | -0.8515 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8775 | -0.8743 | -0.8683 | -0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8746 | -0.8685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.40832 | 93.00 | -5.300 | -0.9500 | -2.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.400 | 0.1900 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.40832</span> | 93.00 | 0.004992 | 0.2789 | 0.1353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01228 | 0.5474 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 10</span>| 494.40832 | 1.000 | -1.000 | -0.9115 | -0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9817 | -0.8883 | -0.8515 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8775 | -0.8743 | -0.8683 | -0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8746 | -0.8685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.40832 | 93.00 | -5.300 | -0.9500 | -2.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.400 | 0.1900 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.40832</span> | 93.00 | 0.004992 | 0.2789 | 0.1353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01228 | 0.5474 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 11</span>| 494.40832 | 1.000 | -1.000 | -0.9115 | -0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9817 | -0.8883 | -0.8515 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8775 | -0.8743 | -0.8683 | -0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8746 | -0.8685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.40832 | 93.00 | -5.300 | -0.9500 | -2.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.400 | 0.1900 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.40832</span> | 93.00 | 0.004992 | 0.2789 | 0.1353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01228 | 0.5474 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 12</span>| 494.40832 | 1.000 | -1.000 | -0.9115 | -0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9817 | -0.8883 | -0.8515 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8775 | -0.8743 | -0.8683 | -0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8746 | -0.8685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.40832 | 93.00 | -5.300 | -0.9500 | -2.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.400 | 0.1900 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.40832</span> | 93.00 | 0.004992 | 0.2789 | 0.1353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01228 | 0.5474 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 13</span>| 494.40832 | 1.000 | -1.000 | -0.9115 | -0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9817 | -0.8883 | -0.8515 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8775 | -0.8743 | -0.8683 | -0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8746 | -0.8685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.40832 | 93.00 | -5.300 | -0.9500 | -2.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.400 | 0.1900 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.40832</span> | 93.00 | 0.004992 | 0.2789 | 0.1353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01228 | 0.5474 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 14</span>| 494.40832 | 1.000 | -1.000 | -0.9115 | -0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9817 | -0.8883 | -0.8515 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8775 | -0.8743 | -0.8683 | -0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8746 | -0.8685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.40832 | 93.00 | -5.300 | -0.9500 | -2.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.400 | 0.1900 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.40832</span> | 93.00 | 0.004992 | 0.2789 | 0.1353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01228 | 0.5474 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 15</span>| 494.40832 | 1.000 | -1.000 | -0.9115 | -0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9817 | -0.8883 | -0.8515 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8775 | -0.8743 | -0.8683 | -0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8746 | -0.8685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.40832 | 93.00 | -5.300 | -0.9500 | -2.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.400 | 0.1900 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.40832</span> | 93.00 | 0.004992 | 0.2789 | 0.1353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01228 | 0.5474 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 16</span>| 494.40832 | 1.000 | -1.000 | -0.9115 | -0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9817 | -0.8883 | -0.8515 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8775 | -0.8743 | -0.8683 | -0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8746 | -0.8685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.40832 | 93.00 | -5.300 | -0.9500 | -2.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.400 | 0.1900 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.40832</span> | 93.00 | 0.004992 | 0.2789 | 0.1353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01228 | 0.5474 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 17</span>| 494.40832 | 1.000 | -1.000 | -0.9115 | -0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9817 | -0.8883 | -0.8515 | -0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8775 | -0.8743 | -0.8683 | -0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8746 | -0.8685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.40832 | 93.00 | -5.300 | -0.9500 | -2.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.400 | 0.1900 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.40832</span> | 93.00 | 0.004992 | 0.2789 | 0.1353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01228 | 0.5474 | 2.000 | 1.100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7210 | 0.8758 | 1.172 | 0.9765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>initial ETAs were nudged; (can control by foceiControl(etaNudge=., etaNudge2=))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>last objective function was not at minimum, possible problems in optimization</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>using R matrix to calculate covariance, can check sandwich or S matrix with $covRS and $covS</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>gradient problems with initial estimate and covariance; see $scaleInfo</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Identical two-component error for all variables is only possible with</span></span> +<span class="r-in"><span class="co"># est = 'focei' in nlmixr</span></span> +<span class="r-in"><span class="va">f_nlmixr_fomc_sfo_focei_tc</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_tc</span><span class="op">[</span><span class="st">"FOMC-SFO"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"focei"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="font-weight: bold;">Key:</span> U: Unscaled Parameters; X: Back-transformed parameters; G: Gill difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> F: Forward difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> C: Central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> M: Mixed forward and central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> Unscaled parameters for Omegas=chol(solve(omega));</span> +<span class="r-out co"><span class="r-pr">#></span> Diagonals are transformed, as specified by foceiControl(diagXform=)</span> +<span class="r-out co"><span class="r-pr">#></span> |-----+---------------+-----------+-----------+-----------+-----------|</span> +<span class="r-out co"><span class="r-pr">#></span> | #| Objective Fun | parent_0 | log_k_A1 |f_parent_qlogis | log_alpha |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| log_beta | sigma_low | rsd_high | o1 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| o2 | o3 | o4 | o5 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 1</span>| 500.20030 | 1.000 | -1.000 | -0.9113 | -0.8944 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.8678 | -0.8916 | -0.8767 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8743 | -0.8675 | -0.8704 | -0.8704 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 500.2003 | 93.00 | -5.300 | -0.9400 | -0.1100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.200 | 0.03000 | 0.7598 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8758 | 1.214 | 1.068 | 1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 500.2003</span> | 93.00 | 0.004992 | 0.2809 | 0.8958 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.200 | 0.03000 | 0.7598 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8758 | 1.214 | 1.068 | 1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> | G| Gill Diff. | 48.88 | 2.383 | 0.1231 | 0.1986 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1571 | -64.31 | -21.89 | 0.6250 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 11.41 | -12.48 | -9.903 | -10.91 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 2</span>| 2909.4393 | 0.4361 | -1.027 | -0.9127 | -0.8967 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8472 | -0.1258 | -0.6390 | -0.8839 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.006 | -0.7235 | -0.7562 | -0.7445 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 2909.4393 | 40.56 | -5.327 | -0.9413 | -0.1123 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.298 | 1.645 | 0.03379 | 0.7544 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7605 | 1.389 | 1.189 | 1.206 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 2909.4393</span> | 40.56 | 0.004856 | 0.2806 | 0.8938 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.956 | 1.645 | 0.03379 | 0.7544 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7605 | 1.389 | 1.189 | 1.206 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 3</span>| 515.24373 | 0.9436 | -1.003 | -0.9114 | -0.8946 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8456 | -0.7936 | -0.8663 | -0.8774 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8875 | -0.8531 | -0.8590 | -0.8578 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 515.24373 | 87.76 | -5.303 | -0.9401 | -0.1102 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.245 | 0.03038 | 0.7593 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8642 | 1.232 | 1.080 | 1.084 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 515.24373</span> | 87.76 | 0.004978 | 0.2809 | 0.8956 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.972 | 1.245 | 0.03038 | 0.7593 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8642 | 1.232 | 1.080 | 1.084 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 4</span>| 499.40695 | 0.9897 | -1.001 | -0.9113 | -0.8944 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.8542 | -0.8869 | -0.8768 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8768 | -0.8648 | -0.8684 | -0.8681 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 499.40695 | 92.04 | -5.301 | -0.9400 | -0.1100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.208 | 0.03007 | 0.7597 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8737 | 1.217 | 1.070 | 1.073 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 499.40695</span> | 92.04 | 0.004989 | 0.2809 | 0.8958 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.208 | 0.03007 | 0.7597 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8737 | 1.217 | 1.070 | 1.073 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -99.71 | 2.245 | -0.1707 | 0.1202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1546 | -61.69 | -22.54 | 1.475 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 7.677 | -11.72 | -9.584 | -10.53 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 5</span>| 498.17135 | 1.001 | -1.001 | -0.9113 | -0.8945 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.8410 | -0.8822 | -0.8771 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8786 | -0.8623 | -0.8663 | -0.8658 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 498.17135 | 93.06 | -5.301 | -0.9400 | -0.1101 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.216 | 0.03014 | 0.7595 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8720 | 1.221 | 1.072 | 1.076 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 498.17135</span> | 93.06 | 0.004987 | 0.2809 | 0.8958 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.216 | 0.03014 | 0.7595 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8720 | 1.221 | 1.072 | 1.076 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 55.25 | 2.349 | 0.1359 | 0.2180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1993 | -60.48 | -20.28 | 1.106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.662 | -11.74 | -9.501 | -10.55 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 6</span>| 497.33758 | 0.9906 | -1.002 | -0.9113 | -0.8945 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.8273 | -0.8776 | -0.8773 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8808 | -0.8596 | -0.8642 | -0.8634 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 497.33758 | 92.12 | -5.302 | -0.9400 | -0.1101 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.224 | 0.03021 | 0.7594 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8701 | 1.224 | 1.074 | 1.078 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 497.33758</span> | 92.12 | 0.004984 | 0.2809 | 0.8957 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.224 | 0.03021 | 0.7594 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8701 | 1.224 | 1.074 | 1.078 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -88.13 | 2.220 | -0.1371 | 0.1382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1101 | -57.44 | -20.90 | 1.111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 7.358 | -11.52 | -9.371 | -10.34 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 7</span>| 496.20963 | 1.001 | -1.002 | -0.9113 | -0.8946 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.8137 | -0.8728 | -0.8776 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8827 | -0.8569 | -0.8620 | -0.8610 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 496.20963 | 93.07 | -5.302 | -0.9400 | -0.1102 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.232 | 0.03028 | 0.7592 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8684 | 1.227 | 1.077 | 1.081 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 496.20963</span> | 93.07 | 0.004981 | 0.2809 | 0.8957 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.232 | 0.03028 | 0.7592 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8684 | 1.227 | 1.077 | 1.081 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 55.31 | 2.316 | 0.1573 | 0.2363 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2327 | -56.27 | -18.79 | 0.9054 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.277 | -11.53 | -9.283 | -10.35 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 8</span>| 495.35926 | 0.9914 | -1.003 | -0.9113 | -0.8946 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.7996 | -0.8680 | -0.8778 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8850 | -0.8541 | -0.8597 | -0.8584 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 495.35926 | 92.20 | -5.303 | -0.9401 | -0.1102 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.241 | 0.03035 | 0.7590 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8664 | 1.231 | 1.079 | 1.084 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 495.35926</span> | 92.20 | 0.004979 | 0.2809 | 0.8956 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.241 | 0.03035 | 0.7590 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8664 | 1.231 | 1.079 | 1.084 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -77.78 | 2.194 | -0.1077 | 0.1552 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06714 | -52.97 | -19.27 | 0.8916 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 7.037 | -11.29 | -9.130 | -10.15 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 9</span>| 494.33654 | 1.001 | -1.003 | -0.9113 | -0.8947 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.7857 | -0.8631 | -0.8780 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8870 | -0.8511 | -0.8573 | -0.8558 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.33654 | 93.09 | -5.303 | -0.9400 | -0.1103 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.249 | 0.03043 | 0.7588 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8647 | 1.234 | 1.082 | 1.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.33654</span> | 93.09 | 0.004976 | 0.2809 | 0.8956 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.249 | 0.03043 | 0.7588 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8647 | 1.234 | 1.082 | 1.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 55.95 | 2.282 | 0.1850 | 0.2507 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2656 | -51.81 | -17.28 | 0.8212 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 7.543 | -11.27 | -9.029 | -10.13 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 10</span>| 493.47922 | 0.9922 | -1.004 | -0.9114 | -0.8947 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.7714 | -0.8582 | -0.8782 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8891 | -0.8480 | -0.8548 | -0.8530 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 493.47922 | 92.28 | -5.304 | -0.9401 | -0.1103 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.258 | 0.03050 | 0.7587 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8629 | 1.238 | 1.084 | 1.090 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 493.47922</span> | 92.28 | 0.004973 | 0.2809 | 0.8955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.258 | 0.03050 | 0.7587 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8629 | 1.238 | 1.084 | 1.090 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -67.18 | 2.173 | -0.07166 | 0.1818 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.01313 | -49.19 | -17.69 | 0.7047 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.114 | -11.03 | -8.882 | -9.923 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 11</span>| 492.53845 | 1.001 | -1.004 | -0.9114 | -0.8948 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8456 | -0.7572 | -0.8532 | -0.8784 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8914 | -0.8448 | -0.8522 | -0.8501 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 492.53845 | 93.09 | -5.304 | -0.9401 | -0.1104 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.266 | 0.03057 | 0.7585 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8608 | 1.242 | 1.087 | 1.093 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 492.53845</span> | 93.09 | 0.004969 | 0.2809 | 0.8955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.972 | 1.266 | 0.03057 | 0.7585 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8608 | 1.242 | 1.087 | 1.093 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 53.38 | 2.243 | 0.1941 | 0.2566 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2879 | -47.96 | -15.83 | 0.7595 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.537 | -10.98 | -8.771 | -9.890 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 12</span>| 491.72645 | 0.9926 | -1.005 | -0.9114 | -0.8949 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8456 | -0.7429 | -0.8484 | -0.8786 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8941 | -0.8415 | -0.8496 | -0.8471 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 491.72645 | 92.31 | -5.305 | -0.9401 | -0.1105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.275 | 0.03065 | 0.7584 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8584 | 1.246 | 1.090 | 1.096 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 491.72645</span> | 92.31 | 0.004966 | 0.2809 | 0.8954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.972 | 1.275 | 0.03065 | 0.7584 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8584 | 1.246 | 1.090 | 1.096 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -63.56 | 2.131 | -0.05387 | 0.1833 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.0009134 | -45.55 | -16.30 | 0.3872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.447 | -10.76 | -8.612 | -9.684 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 13</span>| 490.83850 | 1.001 | -1.006 | -0.9114 | -0.8949 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8457 | -0.7286 | -0.8435 | -0.8787 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8974 | -0.8380 | -0.8468 | -0.8440 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 490.8385 | 93.07 | -5.306 | -0.9401 | -0.1105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.283 | 0.03072 | 0.7583 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8556 | 1.250 | 1.093 | 1.099 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 490.8385</span> | 93.07 | 0.004963 | 0.2809 | 0.8954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.971 | 1.283 | 0.03072 | 0.7583 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8556 | 1.250 | 1.093 | 1.099 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 49.01 | 2.198 | 0.2057 | 0.2666 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3102 | -44.06 | -14.52 | 0.5614 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.039 | -10.72 | -8.482 | -9.628 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 14</span>| 490.09324 | 0.9928 | -1.007 | -0.9115 | -0.8950 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8458 | -0.7143 | -0.8387 | -0.8788 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9004 | -0.8343 | -0.8439 | -0.8407 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 490.09324 | 92.33 | -5.307 | -0.9402 | -0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.292 | 0.03079 | 0.7582 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8529 | 1.254 | 1.096 | 1.103 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 490.09324</span> | 92.33 | 0.004959 | 0.2809 | 0.8953 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.970 | 1.292 | 0.03079 | 0.7582 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8529 | 1.254 | 1.096 | 1.103 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -62.13 | 2.095 | -0.03472 | 0.1999 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03562 | -41.55 | -14.84 | 0.5236 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 7.264 | -10.46 | -8.310 | -9.412 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 15</span>| 489.25271 | 1.001 | -1.007 | -0.9115 | -0.8951 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8458 | -0.7001 | -0.8338 | -0.8789 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9032 | -0.8304 | -0.8408 | -0.8372 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 489.25271 | 93.06 | -5.307 | -0.9402 | -0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.301 | 0.03087 | 0.7581 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8505 | 1.259 | 1.099 | 1.107 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 489.25271</span> | 93.06 | 0.004955 | 0.2809 | 0.8952 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.970 | 1.301 | 0.03087 | 0.7581 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8505 | 1.259 | 1.099 | 1.107 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 44.98 | 2.155 | 0.2191 | 0.2769 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3339 | -40.42 | -13.24 | 0.4473 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 7.595 | -10.35 | -8.165 | -9.335 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 16</span>| 488.54089 | 0.9934 | -1.008 | -0.9116 | -0.8952 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8459 | -0.6857 | -0.8290 | -0.8790 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9061 | -0.8262 | -0.8376 | -0.8335 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 488.54089 | 92.38 | -5.308 | -0.9403 | -0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.299 | 1.309 | 0.03094 | 0.7581 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8479 | 1.264 | 1.103 | 1.111 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 488.54089</span> | 92.38 | 0.004951 | 0.2808 | 0.8951 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.968 | 1.309 | 0.03094 | 0.7581 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8479 | 1.264 | 1.103 | 1.111 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -55.81 | 2.061 | -0.02096 | 0.2050 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.07367 | -38.08 | -13.50 | 0.4111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 6.904 | -10.08 | -7.981 | -9.106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 17</span>| 487.77387 | 1.001 | -1.009 | -0.9116 | -0.8953 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8461 | -0.6716 | -0.8243 | -0.8791 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9092 | -0.8218 | -0.8341 | -0.8294 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 487.77387 | 93.07 | -5.309 | -0.9403 | -0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.299 | 1.318 | 0.03101 | 0.7580 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8453 | 1.270 | 1.106 | 1.115 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 487.77387</span> | 93.07 | 0.004946 | 0.2808 | 0.8950 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.967 | 1.318 | 0.03101 | 0.7580 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8453 | 1.270 | 1.106 | 1.115 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 43.45 | 2.114 | 0.2402 | 0.2940 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3672 | -36.87 | -12.03 | 0.3081 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 7.143 | -10.02 | -7.799 | -9.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 18</span>| 487.09815 | 0.9939 | -1.010 | -0.9118 | -0.8955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8463 | -0.6575 | -0.8197 | -0.8791 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9124 | -0.8169 | -0.8304 | -0.8251 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 487.09815 | 92.43 | -5.310 | -0.9404 | -0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.299 | 1.326 | 0.03108 | 0.7580 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8425 | 1.276 | 1.110 | 1.120 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 487.09815</span> | 92.43 | 0.004941 | 0.2808 | 0.8948 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.965 | 1.326 | 0.03108 | 0.7580 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8425 | 1.276 | 1.110 | 1.120 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -50.03 | 2.024 | 0.005993 | 0.2193 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1119 | -34.69 | -12.26 | 0.2072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 6.453 | -9.722 | -7.597 | -8.758 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 19</span>| 486.39882 | 1.001 | -1.011 | -0.9119 | -0.8957 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8465 | -0.6438 | -0.8151 | -0.8789 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9156 | -0.8116 | -0.8264 | -0.8203 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 486.39882 | 93.07 | -5.311 | -0.9405 | -0.1113 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.299 | 1.334 | 0.03115 | 0.7582 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8396 | 1.282 | 1.114 | 1.125 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 486.39882</span> | 93.07 | 0.004935 | 0.2808 | 0.8947 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.963 | 1.334 | 0.03115 | 0.7582 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8396 | 1.282 | 1.114 | 1.125 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 41.24 | 2.069 | 0.2581 | 0.3038 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3965 | -33.71 | -10.93 | 0.1523 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 5.279 | -9.597 | -7.397 | -8.617 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 20</span>| 485.77269 | 0.9943 | -1.013 | -0.9120 | -0.8959 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8467 | -0.6301 | -0.8107 | -0.8786 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9175 | -0.8058 | -0.8222 | -0.8151 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 485.77269 | 92.47 | -5.313 | -0.9407 | -0.1115 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.299 | 1.343 | 0.03121 | 0.7584 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8380 | 1.289 | 1.119 | 1.130 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 485.77269</span> | 92.47 | 0.004928 | 0.2808 | 0.8945 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.960 | 1.343 | 0.03121 | 0.7584 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8380 | 1.289 | 1.119 | 1.130 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -45.38 | 1.992 | 0.03513 | 0.2356 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1513 | -31.62 | -11.12 | 0.08802 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 6.113 | -9.278 | -7.167 | -8.332 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 21</span>| 485.13787 | 1.001 | -1.014 | -0.9122 | -0.8962 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8471 | -0.6169 | -0.8065 | -0.8780 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9196 | -0.7993 | -0.8176 | -0.8094 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 485.13787 | 93.06 | -5.314 | -0.9409 | -0.1118 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.298 | 1.351 | 0.03128 | 0.7588 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8361 | 1.297 | 1.124 | 1.136 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 485.13787</span> | 93.06 | 0.004921 | 0.2807 | 0.8942 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.957 | 1.351 | 0.03128 | 0.7588 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8361 | 1.297 | 1.124 | 1.136 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 37.95 | 2.033 | 0.2726 | 0.3147 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4223 | -30.68 | -9.906 | 0.05100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.975 | -9.039 | -6.928 | -8.144 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 22</span>| 484.56781 | 0.9947 | -1.016 | -0.9125 | -0.8965 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8476 | -0.6040 | -0.8026 | -0.8774 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9219 | -0.7925 | -0.8127 | -0.8032 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 484.56781 | 92.51 | -5.316 | -0.9411 | -0.1121 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.298 | 1.358 | 0.03133 | 0.7593 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8341 | 1.305 | 1.129 | 1.143 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 484.56781</span> | 92.51 | 0.004912 | 0.2807 | 0.8939 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.952 | 1.358 | 0.03133 | 0.7593 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8341 | 1.305 | 1.129 | 1.143 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -42.28 | 1.959 | 0.05438 | 0.2483 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1829 | -28.95 | -10.12 | -0.04344 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.379 | -8.677 | -6.653 | -7.817 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 23</span>| 484.00832 | 1.000 | -1.018 | -0.9128 | -0.8970 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8481 | -0.5915 | -0.7988 | -0.8764 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9214 | -0.7852 | -0.8076 | -0.7966 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 484.00832 | 93.05 | -5.318 | -0.9414 | -0.1125 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.297 | 1.366 | 0.03139 | 0.7601 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8346 | 1.314 | 1.135 | 1.150 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 484.00832</span> | 93.05 | 0.004901 | 0.2806 | 0.8936 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.947 | 1.366 | 0.03139 | 0.7601 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8346 | 1.314 | 1.135 | 1.150 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 34.54 | 2.001 | 0.2786 | 0.3182 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4381 | -28.02 | -9.026 | -0.09975 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 6.146 | -8.496 | -6.417 | -7.602 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 24</span>| 483.48726 | 0.9952 | -1.021 | -0.9132 | -0.8975 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8489 | -0.5798 | -0.7955 | -0.8750 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9256 | -0.7775 | -0.8025 | -0.7898 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 483.48726 | 92.55 | -5.321 | -0.9418 | -0.1131 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.296 | 1.373 | 0.03144 | 0.7611 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8309 | 1.323 | 1.140 | 1.157 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 483.48726</span> | 92.55 | 0.004889 | 0.2805 | 0.8931 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.939 | 1.373 | 0.03144 | 0.7611 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8309 | 1.323 | 1.140 | 1.157 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -37.52 | 1.926 | 0.07054 | 0.2526 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2102 | -26.43 | -9.184 | -0.1123 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 5.591 | -8.057 | -6.119 | -7.239 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 25</span>| 482.99669 | 1.001 | -1.023 | -0.9136 | -0.8980 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8497 | -0.5700 | -0.7928 | -0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9342 | -0.7702 | -0.7978 | -0.7834 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 482.99669 | 93.05 | -5.323 | -0.9422 | -0.1136 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.296 | 1.379 | 0.03148 | 0.7623 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8234 | 1.332 | 1.145 | 1.164 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 482.99669</span> | 93.05 | 0.004876 | 0.2805 | 0.8926 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.932 | 1.379 | 0.03148 | 0.7623 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8234 | 1.332 | 1.145 | 1.164 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 33.56 | 1.934 | 0.3091 | 0.3219 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4700 | -25.85 | -8.255 | -0.09267 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 5.467 | -7.833 | -5.883 | -7.031 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 26</span>| 482.53338 | 0.9957 | -1.027 | -0.9143 | -0.8987 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8507 | -0.5600 | -0.7904 | -0.8719 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9423 | -0.7626 | -0.7931 | -0.7767 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 482.53338 | 92.60 | -5.327 | -0.9428 | -0.1143 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.295 | 1.385 | 0.03152 | 0.7635 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8163 | 1.342 | 1.150 | 1.171 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 482.53338</span> | 92.60 | 0.004861 | 0.2803 | 0.8920 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.921 | 1.385 | 0.03152 | 0.7635 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8163 | 1.342 | 1.150 | 1.171 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -33.71 | 1.852 | 0.1405 | 0.2615 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2476 | -24.53 | -8.462 | -0.2274 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.657 | -7.455 | -5.599 | -6.689 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 27</span>| 482.07760 | 1.001 | -1.030 | -0.9154 | -0.8996 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8522 | -0.5495 | -0.7881 | -0.8694 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9481 | -0.7546 | -0.7885 | -0.7696 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 482.0776 | 93.06 | -5.330 | -0.9439 | -0.1152 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.293 | 1.391 | 0.03155 | 0.7654 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8112 | 1.351 | 1.155 | 1.179 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 482.0776</span> | 93.06 | 0.004842 | 0.2801 | 0.8912 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.906 | 1.391 | 0.03155 | 0.7654 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8112 | 1.351 | 1.155 | 1.179 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 31.51 | 1.862 | 0.3171 | 0.3253 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4890 | -23.74 | -7.570 | -0.1627 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.673 | -7.176 | -5.365 | -6.441 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 28</span>| 481.65018 | 0.9960 | -1.035 | -0.9168 | -0.9007 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8541 | -0.5386 | -0.7859 | -0.8662 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9515 | -0.7465 | -0.7840 | -0.7624 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 481.65018 | 92.63 | -5.335 | -0.9452 | -0.1163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.291 | 1.398 | 0.03158 | 0.7678 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8082 | 1.361 | 1.160 | 1.187 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 481.65018</span> | 92.63 | 0.004820 | 0.2799 | 0.8902 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.887 | 1.398 | 0.03158 | 0.7678 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8082 | 1.361 | 1.160 | 1.187 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -31.18 | 1.794 | 0.1244 | 0.2518 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2479 | -22.54 | -7.736 | -0.2537 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.155 | -6.794 | -5.094 | -6.088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 29</span>| 481.23911 | 1.000 | -1.041 | -0.9182 | -0.9020 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8564 | -0.5274 | -0.7840 | -0.8624 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9539 | -0.7386 | -0.7800 | -0.7556 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 481.23911 | 93.04 | -5.341 | -0.9465 | -0.1176 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.289 | 1.404 | 0.03161 | 0.7707 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8061 | 1.371 | 1.164 | 1.194 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 481.23911</span> | 93.04 | 0.004792 | 0.2796 | 0.8890 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.865 | 1.404 | 0.03161 | 0.7707 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8061 | 1.371 | 1.164 | 1.194 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 30</span>| 480.84332 | 1.001 | -1.048 | -0.9201 | -0.9037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8593 | -0.5164 | -0.7829 | -0.8573 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9562 | -0.7293 | -0.7754 | -0.7475 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.84332 | 93.06 | -5.348 | -0.9483 | -0.1193 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.286 | 1.411 | 0.03163 | 0.7746 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8041 | 1.382 | 1.169 | 1.203 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.84332</span> | 93.06 | 0.004757 | 0.2792 | 0.8875 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.836 | 1.411 | 0.03163 | 0.7746 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8041 | 1.382 | 1.169 | 1.203 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 31</span>| 479.47395 | 1.001 | -1.077 | -0.9274 | -0.9105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8708 | -0.4737 | -0.7785 | -0.8375 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9655 | -0.6927 | -0.7575 | -0.7158 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.47395 | 93.12 | -5.377 | -0.9551 | -0.1261 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.275 | 1.436 | 0.03170 | 0.7896 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7959 | 1.426 | 1.188 | 1.237 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.47395</span> | 93.12 | 0.004620 | 0.2779 | 0.8816 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.723 | 1.436 | 0.03170 | 0.7896 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7959 | 1.426 | 1.188 | 1.237 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 32</span>| 477.01144 | 1.003 | -1.162 | -0.9485 | -0.9300 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9044 | -0.3493 | -0.7656 | -0.7799 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9925 | -0.5865 | -0.7057 | -0.6237 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 477.01144 | 93.31 | -5.462 | -0.9750 | -0.1456 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.241 | 1.511 | 0.03189 | 0.8334 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7723 | 1.555 | 1.243 | 1.335 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 477.01144</span> | 93.31 | 0.004245 | 0.2739 | 0.8645 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.403 | 1.511 | 0.03189 | 0.8334 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7723 | 1.555 | 1.243 | 1.335 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 48.38 | 1.353 | -0.3553 | -0.05530 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.006768 | -8.661 | -2.325 | -0.1540 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.503 | -0.2811 | -0.6438 | -0.5229 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 33</span>| 477.99463 | 1.002 | -1.284 | -0.8933 | -0.9162 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8846 | -0.1951 | -0.7385 | -0.7367 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.093 | -0.7697 | -0.8046 | -0.7596 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 477.99463 | 93.20 | -5.584 | -0.9231 | -0.1318 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.261 | 1.604 | 0.03230 | 0.8662 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6840 | 1.333 | 1.138 | 1.190 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 477.99463</span> | 93.20 | 0.003757 | 0.2843 | 0.8766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.591 | 1.604 | 0.03230 | 0.8662 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6840 | 1.333 | 1.138 | 1.190 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 34</span>| 476.67952 | 1.000 | -1.201 | -0.9310 | -0.9256 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8981 | -0.3000 | -0.7569 | -0.7662 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.025 | -0.6445 | -0.7370 | -0.6668 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.67952 | 93.04 | -5.501 | -0.9585 | -0.1412 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.247 | 1.541 | 0.03202 | 0.8438 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7442 | 1.485 | 1.210 | 1.289 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.67952</span> | 93.04 | 0.004084 | 0.2772 | 0.8683 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.462 | 1.541 | 0.03202 | 0.8438 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7442 | 1.485 | 1.210 | 1.289 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.308 | 1.138 | 0.3206 | 0.007327 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.005220 | -6.420 | -1.952 | -0.8085 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4295 | -3.531 | -2.349 | -2.485 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 35</span>| 477.00015 | 0.9939 | -1.268 | -0.9234 | -0.9152 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8823 | -0.2647 | -0.7585 | -0.7168 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9725 | -0.6365 | -0.7310 | -0.6853 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 477.00015 | 92.43 | -5.568 | -0.9514 | -0.1308 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.263 | 1.562 | 0.03200 | 0.8813 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7898 | 1.495 | 1.216 | 1.269 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 477.00015</span> | 92.43 | 0.003818 | 0.2786 | 0.8774 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.613 | 1.562 | 0.03200 | 0.8813 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7898 | 1.495 | 1.216 | 1.269 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 36</span>| 476.87328 | 0.9941 | -1.216 | -0.9300 | -0.9236 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8950 | -0.2832 | -0.7542 | -0.7554 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.014 | -0.6375 | -0.7322 | -0.6666 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.87328 | 92.45 | -5.516 | -0.9576 | -0.1392 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.250 | 1.551 | 0.03206 | 0.8520 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7536 | 1.493 | 1.215 | 1.289 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.87328</span> | 92.45 | 0.004024 | 0.2774 | 0.8700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.491 | 1.551 | 0.03206 | 0.8520 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7536 | 1.493 | 1.215 | 1.289 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 37</span>| 476.68202 | 0.9977 | -1.202 | -0.9313 | -0.9256 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8981 | -0.2947 | -0.7553 | -0.7655 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.024 | -0.6416 | -0.7351 | -0.6648 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.68202 | 92.79 | -5.502 | -0.9588 | -0.1412 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.247 | 1.544 | 0.03204 | 0.8443 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7445 | 1.488 | 1.212 | 1.291 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.68202</span> | 92.79 | 0.004080 | 0.2771 | 0.8683 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.462 | 1.544 | 0.03204 | 0.8443 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7445 | 1.488 | 1.212 | 1.291 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 38</span>| 476.66620 | 0.9991 | -1.201 | -0.9311 | -0.9256 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8981 | -0.2974 | -0.7561 | -0.7659 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.024 | -0.6431 | -0.7361 | -0.6658 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.6662 | 92.92 | -5.501 | -0.9587 | -0.1412 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.247 | 1.542 | 0.03203 | 0.8441 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7443 | 1.487 | 1.211 | 1.290 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.6662</span> | 92.92 | 0.004082 | 0.2771 | 0.8683 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.462 | 1.542 | 0.03203 | 0.8441 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7443 | 1.487 | 1.211 | 1.290 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -16.67 | 1.127 | 0.2138 | -0.01630 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1134 | -4.869 | -1.703 | -0.03057 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.03000 | -2.848 | -2.302 | -2.432 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 39</span>| 476.65034 | 1.001 | -1.204 | -0.9308 | -0.9253 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8974 | -0.2967 | -0.7561 | -0.7660 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.024 | -0.6432 | -0.7350 | -0.6655 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.65034 | 93.06 | -5.504 | -0.9584 | -0.1409 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.248 | 1.543 | 0.03203 | 0.8440 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7448 | 1.487 | 1.212 | 1.290 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.65034</span> | 93.06 | 0.004070 | 0.2772 | 0.8686 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.468 | 1.543 | 0.03203 | 0.8440 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7448 | 1.487 | 1.212 | 1.290 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 7.111 | 1.131 | 0.3498 | 0.02199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03596 | -6.336 | -1.893 | -0.8646 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4089 | -3.511 | -2.253 | -2.437 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 40</span>| 476.63921 | 0.9998 | -1.207 | -0.9306 | -0.9249 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8968 | -0.2957 | -0.7561 | -0.7661 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.024 | -0.6430 | -0.7338 | -0.6650 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.63921 | 92.98 | -5.507 | -0.9581 | -0.1405 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.249 | 1.543 | 0.03203 | 0.8439 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7451 | 1.487 | 1.213 | 1.291 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.63921</span> | 92.98 | 0.004058 | 0.2773 | 0.8689 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.474 | 1.543 | 0.03203 | 0.8439 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7451 | 1.487 | 1.213 | 1.291 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -6.837 | 1.116 | 0.2875 | 0.01149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.02542 | -4.741 | -1.572 | 0.01643 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.427 | -2.805 | -2.162 | -2.393 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 41</span>| 476.63321 | 1.001 | -1.209 | -0.9304 | -0.9247 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8965 | -0.2943 | -0.7557 | -0.7669 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.022 | -0.6432 | -0.7330 | -0.6644 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.63321 | 93.07 | -5.509 | -0.9580 | -0.1403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.249 | 1.544 | 0.03204 | 0.8433 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7468 | 1.487 | 1.214 | 1.292 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.63321</span> | 93.07 | 0.004050 | 0.2773 | 0.8691 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.477 | 1.544 | 0.03204 | 0.8433 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7468 | 1.487 | 1.214 | 1.292 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 8.780 | 1.119 | 0.3715 | 0.03544 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06786 | -4.773 | -1.470 | -0.02124 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.265 | -2.850 | -2.132 | -2.390 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 42</span>| 476.62737 | 0.9998 | -1.211 | -0.9303 | -0.9246 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8963 | -0.2932 | -0.7554 | -0.7683 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.020 | -0.6436 | -0.7322 | -0.6637 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.62737 | 92.98 | -5.511 | -0.9578 | -0.1402 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.249 | 1.545 | 0.03204 | 0.8422 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7485 | 1.486 | 1.215 | 1.292 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.62737</span> | 92.98 | 0.004043 | 0.2773 | 0.8692 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.479 | 1.545 | 0.03204 | 0.8422 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7485 | 1.486 | 1.215 | 1.292 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.468 | 1.108 | 0.2964 | 0.01787 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.01029 | -4.584 | -1.512 | -0.04750 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.233 | -2.839 | -2.097 | -2.338 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 43</span>| 476.62183 | 1.001 | -1.213 | -0.9301 | -0.9245 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8960 | -0.2918 | -0.7549 | -0.7696 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.018 | -0.6438 | -0.7313 | -0.6628 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.62183 | 93.07 | -5.513 | -0.9577 | -0.1401 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.249 | 1.546 | 0.03205 | 0.8412 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7501 | 1.486 | 1.216 | 1.293 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.62183</span> | 93.07 | 0.004035 | 0.2773 | 0.8693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.481 | 1.546 | 0.03205 | 0.8412 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7501 | 1.486 | 1.216 | 1.293 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 8.726 | 1.111 | 0.3721 | 0.03969 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.07339 | -4.588 | -1.391 | -0.04583 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.059 | -2.851 | -2.052 | -2.306 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 44</span>| 476.61645 | 0.9998 | -1.215 | -0.9300 | -0.9243 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8958 | -0.2908 | -0.7546 | -0.7711 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.016 | -0.6442 | -0.7306 | -0.6621 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.61645 | 92.98 | -5.515 | -0.9576 | -0.1399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.250 | 1.546 | 0.03205 | 0.8401 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7517 | 1.485 | 1.217 | 1.294 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.61645</span> | 92.98 | 0.004027 | 0.2774 | 0.8694 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.484 | 1.546 | 0.03205 | 0.8401 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7517 | 1.485 | 1.217 | 1.294 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.224 | 1.099 | 0.2980 | 0.02349 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.002638 | -4.438 | -1.447 | -0.09166 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4490 | -2.896 | -2.021 | -2.267 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 45</span>| 476.60491 | 1.001 | -1.217 | -0.9300 | -0.9242 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8956 | -0.2899 | -0.7543 | -0.7729 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.016 | -0.6437 | -0.7294 | -0.6608 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.60491 | 93.08 | -5.517 | -0.9576 | -0.1398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.250 | 1.547 | 0.03206 | 0.8387 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7514 | 1.486 | 1.218 | 1.295 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.60491</span> | 93.08 | 0.004018 | 0.2774 | 0.8695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.485 | 1.547 | 0.03206 | 0.8387 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7514 | 1.486 | 1.218 | 1.295 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 9.891 | 1.101 | 0.3805 | 0.04781 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.09121 | -4.602 | -1.355 | -0.1211 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9908 | -2.875 | -1.954 | -2.212 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 46</span>| 476.59275 | 0.9999 | -1.219 | -0.9301 | -0.9241 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8954 | -0.2896 | -0.7542 | -0.7748 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.017 | -0.6434 | -0.7284 | -0.6597 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.59275 | 92.99 | -5.519 | -0.9576 | -0.1397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.250 | 1.547 | 0.03206 | 0.8373 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7512 | 1.486 | 1.219 | 1.297 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.59275</span> | 92.99 | 0.004009 | 0.2774 | 0.8696 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.487 | 1.547 | 0.03206 | 0.8373 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7512 | 1.486 | 1.219 | 1.297 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.741 | 1.086 | 0.3018 | 0.02978 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01334 | -4.300 | -1.393 | -0.08082 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4335 | -2.821 | -1.884 | -2.156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 47</span>| 476.58049 | 1.001 | -1.222 | -0.9302 | -0.9241 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8953 | -0.2889 | -0.7541 | -0.7767 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.017 | -0.6427 | -0.7275 | -0.6585 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.58049 | 93.06 | -5.522 | -0.9577 | -0.1397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.250 | 1.547 | 0.03206 | 0.8359 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7507 | 1.487 | 1.220 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.58049</span> | 93.06 | 0.003999 | 0.2773 | 0.8697 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.488 | 1.547 | 0.03206 | 0.8359 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7507 | 1.487 | 1.220 | 1.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 48</span>| 476.57085 | 1.001 | -1.225 | -0.9302 | -0.9239 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8951 | -0.2891 | -0.7542 | -0.7796 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.018 | -0.6424 | -0.7265 | -0.6573 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.57085 | 93.06 | -5.525 | -0.9578 | -0.1395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.250 | 1.547 | 0.03206 | 0.8336 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7502 | 1.488 | 1.221 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.57085</span> | 93.06 | 0.003985 | 0.2773 | 0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.490 | 1.547 | 0.03206 | 0.8336 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7502 | 1.488 | 1.221 | 1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 49</span>| 476.52700 | 1.000 | -1.243 | -0.9306 | -0.9233 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8940 | -0.2898 | -0.7549 | -0.7948 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.021 | -0.6409 | -0.7216 | -0.6509 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.527 | 93.02 | -5.543 | -0.9582 | -0.1389 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.251 | 1.547 | 0.03205 | 0.8221 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7475 | 1.489 | 1.226 | 1.306 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.527</span> | 93.02 | 0.003915 | 0.2772 | 0.8703 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.501 | 1.547 | 0.03205 | 0.8221 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7475 | 1.489 | 1.226 | 1.306 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 50</span>| 476.45166 | 0.9988 | -1.314 | -0.9321 | -0.9209 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8895 | -0.2927 | -0.7576 | -0.8554 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.033 | -0.6351 | -0.7022 | -0.6254 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.45166 | 92.89 | -5.614 | -0.9596 | -0.1365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.256 | 1.545 | 0.03201 | 0.7760 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7365 | 1.496 | 1.247 | 1.333 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.45166</span> | 92.89 | 0.003648 | 0.2770 | 0.8724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.543 | 1.545 | 0.03201 | 0.7760 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7365 | 1.496 | 1.247 | 1.333 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -21.31 | 0.8191 | 0.2022 | 0.1018 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1327 | -4.505 | -1.303 | -1.202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.080 | -2.304 | -0.3706 | -0.4948 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 51</span>| 476.56836 | 1.004 | -1.424 | -0.9336 | -0.9183 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8856 | -0.2810 | -0.7637 | -0.9206 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.004 | -0.6303 | -0.6962 | -0.6148 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.56836 | 93.36 | -5.724 | -0.9609 | -0.1338 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.260 | 1.552 | 0.03192 | 0.7265 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7619 | 1.502 | 1.254 | 1.345 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.56836</span> | 93.36 | 0.003266 | 0.2767 | 0.8747 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.581 | 1.552 | 0.03192 | 0.7265 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7619 | 1.502 | 1.254 | 1.345 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 52</span>| 476.44457 | 1.002 | -1.351 | -0.9326 | -0.9200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8882 | -0.2885 | -0.7595 | -0.8773 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.024 | -0.6333 | -0.7001 | -0.6218 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.44457 | 93.15 | -5.651 | -0.9600 | -0.1356 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.257 | 1.548 | 0.03198 | 0.7594 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7451 | 1.499 | 1.249 | 1.337 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.44457</span> | 93.15 | 0.003514 | 0.2769 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.556 | 1.548 | 0.03198 | 0.7594 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7451 | 1.499 | 1.249 | 1.337 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 15.82 | 0.7276 | 0.3571 | 0.1746 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4004 | -4.436 | -0.9222 | -1.572 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.287 | -2.164 | -0.2873 | -0.3883 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 53</span>| 476.40417 | 1.000 | -1.371 | -0.9349 | -0.9209 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8904 | -0.2869 | -0.7634 | -0.8782 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.024 | -0.6262 | -0.7046 | -0.6250 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.40417 | 93.02 | -5.671 | -0.9622 | -0.1365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.255 | 1.549 | 0.03192 | 0.7587 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7444 | 1.507 | 1.245 | 1.334 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.40417</span> | 93.02 | 0.003446 | 0.2764 | 0.8724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.535 | 1.549 | 0.03192 | 0.7587 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7444 | 1.507 | 1.245 | 1.334 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 54</span>| 476.37918 | 1.000 | -1.391 | -0.9372 | -0.9218 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8927 | -0.2856 | -0.7675 | -0.8792 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.025 | -0.6191 | -0.7092 | -0.6283 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.37918 | 93.03 | -5.691 | -0.9644 | -0.1374 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.253 | 1.549 | 0.03186 | 0.7580 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7434 | 1.516 | 1.240 | 1.330 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.37918</span> | 93.03 | 0.003376 | 0.2760 | 0.8716 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.513 | 1.549 | 0.03186 | 0.7580 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7434 | 1.516 | 1.240 | 1.330 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 55</span>| 476.33357 | 1.001 | -1.461 | -0.9453 | -0.9249 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9004 | -0.2814 | -0.7818 | -0.8827 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.029 | -0.5944 | -0.7253 | -0.6399 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.33357 | 93.07 | -5.761 | -0.9719 | -0.1405 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.245 | 1.552 | 0.03165 | 0.7553 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7403 | 1.546 | 1.222 | 1.318 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.33357</span> | 93.07 | 0.003146 | 0.2745 | 0.8689 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.440 | 1.552 | 0.03165 | 0.7553 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7403 | 1.546 | 1.222 | 1.318 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.553 | 0.4475 | -0.2195 | 0.07220 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.05655 | -4.350 | -1.061 | -1.750 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1436 | -0.4527 | -1.673 | -1.245 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 56</span>| 476.20746 | 1.002 | -1.571 | -0.9452 | -0.9313 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9123 | -0.2680 | -0.8139 | -0.8382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.032 | -0.6009 | -0.7081 | -0.6381 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.20746 | 93.20 | -5.871 | -0.9719 | -0.1469 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.233 | 1.560 | 0.03117 | 0.7891 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7373 | 1.538 | 1.241 | 1.320 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.20746</span> | 93.20 | 0.002821 | 0.2745 | 0.8634 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.328 | 1.560 | 0.03117 | 0.7891 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7373 | 1.538 | 1.241 | 1.320 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 12.15 | 0.1791 | -0.01894 | -0.004675 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06593 | -5.850 | -1.512 | -1.794 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.396 | -1.647 | -0.7085 | -1.309 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 57</span>| 476.15444 | 1.000 | -1.669 | -0.9317 | -0.9229 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8889 | -0.2480 | -0.8424 | -0.7961 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.030 | -0.6117 | -0.7275 | -0.5959 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.15444 | 93.03 | -5.969 | -0.9591 | -0.1385 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.256 | 1.572 | 0.03074 | 0.8211 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7395 | 1.525 | 1.220 | 1.365 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.15444</span> | 93.03 | 0.002558 | 0.2771 | 0.8707 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.549 | 1.572 | 0.03074 | 0.8211 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7395 | 1.525 | 1.220 | 1.365 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -13.97 | -0.09883 | 0.5245 | 0.1410 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.5845 | -3.407 | -1.272 | -0.2800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9652 | -1.487 | -1.684 | 0.3572 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 58</span>| 476.18235 | 1.000 | -1.690 | -0.9781 | -0.8961 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8818 | -0.1915 | -0.8548 | -0.7635 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.041 | -0.6068 | -0.6702 | -0.6625 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.18235 | 93.04 | -5.990 | -1.003 | -0.1117 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.264 | 1.606 | 0.03055 | 0.8458 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7299 | 1.531 | 1.281 | 1.294 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.18235</span> | 93.04 | 0.002505 | 0.2684 | 0.8943 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.617 | 1.606 | 0.03055 | 0.8458 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7299 | 1.531 | 1.281 | 1.294 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 59</span>| 476.08231 | 1.003 | -1.678 | -0.9530 | -0.9107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8858 | -0.2215 | -0.8479 | -0.7811 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.035 | -0.6092 | -0.7010 | -0.6265 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.08231 | 93.25 | -5.978 | -0.9792 | -0.1263 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.260 | 1.588 | 0.03066 | 0.8325 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7350 | 1.528 | 1.248 | 1.332 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.08231</span> | 93.25 | 0.002533 | 0.2730 | 0.8814 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.579 | 1.588 | 0.03066 | 0.8325 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7350 | 1.528 | 1.248 | 1.332 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 18.25 | -0.08933 | -0.2508 | 0.5157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8830 | -3.835 | -1.133 | -1.026 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.010 | -2.153 | -0.2439 | -1.007 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 60</span>| 476.03808 | 1.001 | -1.672 | -0.9320 | -0.9310 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9291 | -0.2079 | -0.8419 | -0.7733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.039 | -0.6026 | -0.6913 | -0.6380 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.03808 | 93.13 | -5.972 | -0.9594 | -0.1466 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.216 | 1.596 | 0.03074 | 0.8384 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7314 | 1.536 | 1.259 | 1.320 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.03808</span> | 93.13 | 0.002548 | 0.2770 | 0.8636 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.173 | 1.596 | 0.03074 | 0.8384 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7314 | 1.536 | 1.259 | 1.320 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.407 | -0.06545 | 0.6727 | 0.05373 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4541 | -1.330 | -0.5709 | -0.1224 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8702 | -1.228 | 0.2640 | -1.506 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 61</span>| 476.03300 | 1.003 | -1.664 | -0.9621 | -0.9598 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9520 | -0.2020 | -0.8337 | -0.7650 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.042 | -0.6106 | -0.7076 | -0.6154 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.033 | 93.29 | -5.964 | -0.9878 | -0.1754 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.193 | 1.599 | 0.03087 | 0.8447 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7289 | 1.526 | 1.241 | 1.344 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.033</span> | 93.29 | 0.002569 | 0.2714 | 0.8391 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.966 | 1.599 | 0.03087 | 0.8447 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7289 | 1.526 | 1.241 | 1.344 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 15.25 | -0.008049 | -0.5780 | -0.5632 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9601 | -0.9870 | -0.1614 | -0.08306 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3446 | -1.564 | -0.5735 | -0.5777 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 62</span>| 475.98457 | 1.001 | -1.657 | -0.9620 | -0.9650 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9284 | -0.2016 | -0.8312 | -0.7567 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.045 | -0.6004 | -0.7091 | -0.6133 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.98457 | 93.13 | -5.957 | -0.9877 | -0.1806 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.217 | 1.600 | 0.03091 | 0.8511 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7262 | 1.538 | 1.240 | 1.346 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.98457</span> | 93.13 | 0.002588 | 0.2714 | 0.8347 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.180 | 1.600 | 0.03091 | 0.8511 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7262 | 1.538 | 1.240 | 1.346 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 63</span>| 475.96536 | 1.003 | -1.649 | -0.9620 | -0.9705 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9043 | -0.2014 | -0.8286 | -0.7480 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.048 | -0.5903 | -0.7109 | -0.6113 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.96536 | 93.24 | -5.949 | -0.9876 | -0.1861 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.241 | 1.600 | 0.03094 | 0.8576 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7235 | 1.551 | 1.238 | 1.349 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.96536</span> | 93.24 | 0.002608 | 0.2714 | 0.8302 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.403 | 1.600 | 0.03094 | 0.8576 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7235 | 1.551 | 1.238 | 1.349 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 64</span>| 476.05821 | 1.003 | -1.627 | -0.9618 | -0.9866 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8332 | -0.2007 | -0.8211 | -0.7226 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.057 | -0.5602 | -0.7159 | -0.6052 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.05821 | 93.28 | -5.927 | -0.9874 | -0.2022 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.312 | 1.600 | 0.03106 | 0.8769 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7156 | 1.587 | 1.233 | 1.355 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.05821</span> | 93.28 | 0.002666 | 0.2714 | 0.8169 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 10.10 | 1.600 | 0.03106 | 0.8769 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7156 | 1.587 | 1.233 | 1.355 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 11.90 | 0.05098 | -0.6601 | -0.8657 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4347 | -0.9523 | -0.3178 | -0.1283 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1024 | -0.7800 | -0.7284 | -0.4981 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 65</span>| 476.00714 | 1.001 | -1.643 | -0.9512 | -0.8390 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8932 | -0.2051 | -0.7956 | -0.7365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.045 | -0.5599 | -0.7127 | -0.5744 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.00714 | 93.11 | -5.943 | -0.9775 | -0.05460 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.252 | 1.598 | 0.03144 | 0.8663 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7264 | 1.588 | 1.236 | 1.388 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.00714</span> | 93.11 | 0.002624 | 0.2734 | 0.9469 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.508 | 1.598 | 0.03144 | 0.8663 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7264 | 1.588 | 1.236 | 1.388 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 66</span>| 475.93814 | 1.000 | -1.647 | -0.9575 | -0.9171 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8999 | -0.2027 | -0.8152 | -0.7434 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.047 | -0.5779 | -0.7115 | -0.5963 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.93814 | 93.01 | -5.947 | -0.9834 | -0.1327 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.245 | 1.599 | 0.03115 | 0.8612 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7247 | 1.566 | 1.237 | 1.365 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.93814</span> | 93.01 | 0.002614 | 0.2722 | 0.8757 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.445 | 1.599 | 0.03115 | 0.8612 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7247 | 1.566 | 1.237 | 1.365 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -23.67 | 0.03897 | -0.7058 | 0.2979 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2507 | -0.5051 | -0.4675 | -0.05050 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.329 | -0.1594 | -0.7628 | 0.1885 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 67</span>| 475.98668 | 1.003 | -1.653 | -0.9119 | -0.8938 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8940 | -0.2050 | -0.7980 | -0.7479 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.040 | -0.5617 | -0.7056 | -0.5853 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.98668 | 93.26 | -5.953 | -0.9406 | -0.1094 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.251 | 1.598 | 0.03140 | 0.8577 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7310 | 1.586 | 1.243 | 1.376 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.98668</span> | 93.26 | 0.002598 | 0.2808 | 0.8964 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.501 | 1.598 | 0.03140 | 0.8577 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7310 | 1.586 | 1.243 | 1.376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 68</span>| 475.93401 | 1.003 | -1.649 | -0.9419 | -0.9092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8979 | -0.2035 | -0.8093 | -0.7449 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.044 | -0.5723 | -0.7094 | -0.5925 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.93401 | 93.26 | -5.949 | -0.9687 | -0.1248 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.247 | 1.599 | 0.03123 | 0.8600 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7270 | 1.573 | 1.239 | 1.369 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.93401</span> | 93.26 | 0.002609 | 0.2751 | 0.8827 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.464 | 1.599 | 0.03123 | 0.8600 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7270 | 1.573 | 1.239 | 1.369 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 21.62 | 0.03755 | 0.3553 | 0.5344 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.5780 | -0.8226 | -0.2181 | -0.2167 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.049 | 0.002537 | -0.7279 | 0.2347 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 69</span>| 475.92580 | 1.001 | -1.653 | -0.9417 | -0.9124 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8966 | -0.2037 | -0.8058 | -0.7501 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.041 | -0.5739 | -0.7048 | -0.5926 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.9258 | 93.12 | -5.953 | -0.9686 | -0.1280 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.249 | 1.598 | 0.03129 | 0.8560 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7297 | 1.571 | 1.244 | 1.369 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.9258</span> | 93.12 | 0.002598 | 0.2752 | 0.8798 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.476 | 1.598 | 0.03129 | 0.8560 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7297 | 1.571 | 1.244 | 1.369 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.238 | 0.003180 | 0.2025 | 0.4289 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4493 | -0.2935 | -0.2270 | -0.1209 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3327 | -0.04065 | -0.4864 | 0.2705 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 70</span>| 475.92421 | 1.002 | -1.655 | -0.9475 | -0.9180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8971 | -0.2051 | -0.8017 | -0.7499 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.041 | -0.5760 | -0.7024 | -0.5951 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.92421 | 93.14 | -5.955 | -0.9740 | -0.1336 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.248 | 1.598 | 0.03135 | 0.8562 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7299 | 1.568 | 1.247 | 1.366 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.92421</span> | 93.14 | 0.002593 | 0.2741 | 0.8749 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.472 | 1.598 | 0.03135 | 0.8562 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7299 | 1.568 | 1.247 | 1.366 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.572 | 0.0005078 | -0.07939 | 0.3039 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4520 | -0.5123 | -0.2298 | -0.1955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3506 | -0.1759 | -0.3471 | 0.1717 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 71</span>| 475.91356 | 1.001 | -1.654 | -0.9476 | -0.9223 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8992 | -0.2071 | -0.7965 | -0.7440 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.043 | -0.5749 | -0.7035 | -0.5974 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.91356 | 93.12 | -5.954 | -0.9741 | -0.1379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.246 | 1.596 | 0.03143 | 0.8607 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7278 | 1.569 | 1.246 | 1.363 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.91356</span> | 93.12 | 0.002596 | 0.2741 | 0.8712 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.452 | 1.596 | 0.03143 | 0.8607 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7278 | 1.569 | 1.246 | 1.363 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 72</span>| 475.89054 | 1.001 | -1.650 | -0.9479 | -0.9349 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9054 | -0.2136 | -0.7808 | -0.7261 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.051 | -0.5716 | -0.7071 | -0.6043 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.89054 | 93.11 | -5.950 | -0.9744 | -0.1505 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.240 | 1.592 | 0.03166 | 0.8742 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7214 | 1.574 | 1.242 | 1.356 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.89054</span> | 93.11 | 0.002606 | 0.2740 | 0.8602 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.393 | 1.592 | 0.03166 | 0.8742 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7214 | 1.574 | 1.242 | 1.356 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.467 | 0.05330 | -0.1133 | -0.1045 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1362 | -0.3304 | -0.2172 | 0.04726 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.416 | 0.08323 | -0.4566 | -0.2851 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 73</span>| 476.06529 | 1.002 | -1.688 | -0.8959 | -0.9784 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9076 | -0.2354 | -0.6823 | -0.7302 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.035 | -0.5603 | -0.6700 | -0.6079 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.06529 | 93.20 | -5.988 | -0.9255 | -0.1940 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.238 | 1.579 | 0.03314 | 0.8712 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7347 | 1.587 | 1.281 | 1.352 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.06529</span> | 93.20 | 0.002510 | 0.2838 | 0.8236 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.372 | 1.579 | 0.03314 | 0.8712 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7347 | 1.587 | 1.281 | 1.352 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 74</span>| 475.89054 | 1.001 | -1.650 | -0.9479 | -0.9349 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9054 | -0.2136 | -0.7808 | -0.7261 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.051 | -0.5716 | -0.7071 | -0.6043 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.89054 | 93.11 | -5.950 | -0.9744 | -0.1505 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.240 | 1.592 | 0.03166 | 0.8742 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7214 | 1.574 | 1.242 | 1.356 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.89054</span> | 93.11 | 0.002606 | 0.2740 | 0.8602 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.393 | 1.592 | 0.03166 | 0.8742 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7214 | 1.574 | 1.242 | 1.356 |</span> +<span class="r-out co"><span class="r-pr">#></span> calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>initial ETAs were nudged; (can control by foceiControl(etaNudge=., etaNudge2=))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>ETAs were reset to zero during optimization; (Can control by foceiControl(resetEtaP=.))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>gradient problems with initial estimate and covariance; see $scaleInfo</span> +<span class="r-in"><span class="va">f_nlmixr_dfop_sfo_focei_tc</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_tc</span><span class="op">[</span><span class="st">"DFOP-SFO"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"focei"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="font-weight: bold;">Key:</span> U: Unscaled Parameters; X: Back-transformed parameters; G: Gill difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> F: Forward difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> C: Central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> M: Mixed forward and central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> Unscaled parameters for Omegas=chol(solve(omega));</span> +<span class="r-out co"><span class="r-pr">#></span> Diagonals are transformed, as specified by foceiControl(diagXform=)</span> +<span class="r-out co"><span class="r-pr">#></span> |-----+---------------+-----------+-----------+-----------+-----------|</span> +<span class="r-out co"><span class="r-pr">#></span> | #| Objective Fun | parent_0 | log_k_A1 |f_parent_qlogis | log_k1 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| log_k2 | g_qlogis | sigma_low | rsd_high |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| o1 | o2 | o3 | o4 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| o5 | o6 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 1</span>| 495.48573 | 1.000 | -1.000 | -0.9104 | -0.9376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9875 | -0.8823 | -0.8746 | -0.8907 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8767 | -0.8731 | -0.8673 | -0.8720 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8739 | -0.8666 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 495.48573 | 91.00 | -5.200 | -0.8900 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.600 | 0.4600 | 0.8300 | 0.05800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7311 | 0.9036 | 1.183 | 0.9554 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.214 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 495.48573</span> | 91.00 | 0.005517 | 0.2911 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01005 | 0.6130 | 0.8300 | 0.05800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7311 | 0.9036 | 1.183 | 0.9554 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8633 | 1.214 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | G| Gill Diff. | -0.9650 | 2.223 | -0.3153 | -0.01817 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3350 | 0.6789 | -29.17 | -19.58 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9642 | 9.851 | -11.94 | -1.319 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 8.578 | -12.45 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 2</span>| 487.27153 | 1.023 | -1.054 | -0.9028 | -0.9372 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9794 | -0.8987 | -0.1695 | -0.4175 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9000 | -1.111 | -0.5788 | -0.8401 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.081 | -0.5657 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 487.27153 | 93.12 | -5.254 | -0.8832 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.592 | 0.4525 | 1.123 | 0.07172 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7141 | 0.6884 | 1.525 | 0.9859 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6843 | 1.580 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 487.27153</span> | 93.12 | 0.005228 | 0.2925 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01013 | 0.6112 | 1.123 | 0.07172 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7141 | 0.6884 | 1.525 | 0.9859 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6843 | 1.580 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 131.2 | 1.375 | 2.844 | -0.2311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2724 | 0.4206 | 9.234 | 14.82 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3432 | -1.547 | -2.137 | 2.699 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -4.845 | -6.389 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 3</span>| 3806.3530 | 0.1967 | -1.082 | -0.9181 | -0.9356 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9782 | -0.9073 | 0.02635 | -0.3409 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9062 | -1.204 | -0.4610 | -0.8458 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.125 | -0.4164 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 3806.353 | 17.90 | -5.282 | -0.8969 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.591 | 0.4485 | 1.204 | 0.07394 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7095 | 0.6043 | 1.664 | 0.9805 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6463 | 1.761 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 3806.353</span> | 17.90 | 0.005083 | 0.2897 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01015 | 0.6103 | 1.204 | 0.07394 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7095 | 0.6043 | 1.664 | 0.9805 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6463 | 1.761 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 4</span>| 498.29847 | 0.9363 | -1.055 | -0.9047 | -0.9370 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9796 | -0.8990 | -0.1756 | -0.4273 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8998 | -1.110 | -0.5773 | -0.8419 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.078 | -0.5615 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 498.29847 | 85.20 | -5.255 | -0.8849 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.592 | 0.4523 | 1.120 | 0.07144 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7142 | 0.6894 | 1.526 | 0.9842 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6871 | 1.585 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 498.29847</span> | 85.20 | 0.005223 | 0.2922 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01013 | 0.6112 | 1.120 | 0.07144 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7142 | 0.6894 | 1.526 | 0.9842 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6871 | 1.585 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 5</span>| 485.66266 | 1.001 | -1.054 | -0.9033 | -0.9372 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9795 | -0.8988 | -0.1711 | -0.4200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8999 | -1.111 | -0.5784 | -0.8406 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.080 | -0.5646 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 485.66266 | 91.08 | -5.254 | -0.8836 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.592 | 0.4524 | 1.122 | 0.07165 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7141 | 0.6887 | 1.525 | 0.9855 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6850 | 1.581 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 485.66266</span> | 91.08 | 0.005227 | 0.2924 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01013 | 0.6112 | 1.122 | 0.07165 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7141 | 0.6887 | 1.525 | 0.9855 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6850 | 1.581 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.221 | 1.276 | 0.8286 | 0.07146 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3378 | 0.6177 | 8.950 | 14.42 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.232 | -2.934 | -2.090 | 2.822 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -4.031 | -6.085 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 6</span>| 485.32609 | 0.9950 | -1.055 | -0.9042 | -0.9372 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9799 | -0.8995 | -0.1813 | -0.4364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8974 | -1.108 | -0.5760 | -0.8438 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.076 | -0.5577 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 485.32609 | 90.54 | -5.255 | -0.8845 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.592 | 0.4521 | 1.118 | 0.07117 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7160 | 0.6917 | 1.528 | 0.9824 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6890 | 1.589 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 485.32609</span> | 90.54 | 0.005219 | 0.2922 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01013 | 0.6111 | 1.118 | 0.07117 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7160 | 0.6917 | 1.528 | 0.9824 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6890 | 1.589 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -30.72 | 1.256 | 0.2407 | 0.1468 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3576 | 0.6982 | 8.550 | 13.79 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.152 | -3.092 | -1.869 | 2.672 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -3.399 | -5.827 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 7</span>| 484.94767 | 1.003 | -1.055 | -0.9045 | -0.9373 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9801 | -0.8996 | -0.1956 | -0.4497 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8963 | -1.103 | -0.5795 | -0.8455 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.071 | -0.5595 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 484.94767 | 91.28 | -5.255 | -0.8848 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.593 | 0.4521 | 1.112 | 0.07079 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7168 | 0.6961 | 1.524 | 0.9808 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6930 | 1.587 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 484.94767</span> | 91.28 | 0.005220 | 0.2922 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01013 | 0.6111 | 1.112 | 0.07079 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7168 | 0.6961 | 1.524 | 0.9808 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6930 | 1.587 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 16.95 | 1.308 | 0.9181 | 0.03760 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3308 | 0.6549 | 8.124 | 13.74 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.975 | -2.369 | -2.107 | 2.437 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -3.334 | -5.928 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 8</span>| 484.63747 | 0.9965 | -1.055 | -0.9051 | -0.9373 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9805 | -0.8998 | -0.2100 | -0.4642 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8952 | -1.098 | -0.5823 | -0.8472 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.5602 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 484.63747 | 90.68 | -5.255 | -0.8853 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.593 | 0.4520 | 1.106 | 0.07037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7176 | 0.7002 | 1.521 | 0.9792 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6968 | 1.586 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 484.63747</span> | 90.68 | 0.005220 | 0.2921 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01012 | 0.6111 | 1.106 | 0.07037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7176 | 0.7002 | 1.521 | 0.9792 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6968 | 1.586 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -22.67 | 1.288 | 0.2773 | 0.1211 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3459 | 0.7203 | 8.028 | 13.24 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.967 | -2.555 | -2.117 | 2.333 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.789 | -5.812 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 9</span>| 484.31288 | 1.003 | -1.055 | -0.9054 | -0.9374 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9808 | -0.9000 | -0.2248 | -0.4783 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8942 | -1.094 | -0.5856 | -0.8486 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.063 | -0.5617 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 484.31288 | 91.27 | -5.255 | -0.8855 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.593 | 0.4519 | 1.100 | 0.06996 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7183 | 0.7043 | 1.517 | 0.9778 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7003 | 1.585 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 484.31288</span> | 91.27 | 0.005220 | 0.2920 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01012 | 0.6111 | 1.100 | 0.06996 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7183 | 0.7043 | 1.517 | 0.9778 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7003 | 1.585 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 16.32 | 1.333 | 0.8110 | 0.03416 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3225 | 0.6774 | 7.502 | 12.95 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.990 | -1.849 | -2.190 | 2.193 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.714 | -5.891 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 10</span>| 484.03445 | 0.9966 | -1.055 | -0.9058 | -0.9374 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9811 | -0.9003 | -0.2393 | -0.4932 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8929 | -1.090 | -0.5881 | -0.8501 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.059 | -0.5620 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 484.03445 | 90.69 | -5.255 | -0.8859 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.594 | 0.4517 | 1.094 | 0.06953 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7192 | 0.7079 | 1.514 | 0.9764 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7034 | 1.584 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 484.03445</span> | 90.69 | 0.005219 | 0.2919 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01012 | 0.6110 | 1.094 | 0.06953 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7192 | 0.7079 | 1.514 | 0.9764 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7034 | 1.584 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -23.34 | 1.311 | 0.1997 | 0.1136 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3397 | 0.7422 | 7.043 | 12.17 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.843 | -2.075 | -2.300 | 2.141 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.235 | -5.778 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 11</span>| 483.72794 | 1.003 | -1.056 | -0.9061 | -0.9374 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9815 | -0.9008 | -0.2540 | -0.5081 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8918 | -1.086 | -0.5906 | -0.8514 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.056 | -0.5623 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 483.72794 | 91.28 | -5.256 | -0.8861 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.594 | 0.4515 | 1.088 | 0.06909 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7200 | 0.7113 | 1.511 | 0.9751 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7061 | 1.584 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 483.72794</span> | 91.28 | 0.005217 | 0.2919 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01011 | 0.6110 | 1.088 | 0.06909 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7200 | 0.7113 | 1.511 | 0.9751 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7061 | 1.584 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 16.56 | 1.355 | 0.7367 | 0.03002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3166 | 0.7021 | 6.528 | 11.89 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.880 | -1.512 | -2.404 | 1.917 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.215 | -5.846 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 12</span>| 483.44272 | 0.9974 | -1.057 | -0.9064 | -0.9375 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9820 | -0.9016 | -0.2678 | -0.5243 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8904 | -1.083 | -0.5914 | -0.8528 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.054 | -0.5601 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 483.44272 | 90.76 | -5.257 | -0.8865 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.594 | 0.4511 | 1.082 | 0.06862 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7211 | 0.7141 | 1.510 | 0.9738 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7081 | 1.587 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 483.44272</span> | 90.76 | 0.005212 | 0.2918 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01011 | 0.6109 | 1.082 | 0.06862 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7211 | 0.7141 | 1.510 | 0.9738 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7081 | 1.587 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -19.50 | 1.332 | 0.2061 | 0.1022 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3336 | 0.7519 | 5.944 | 11.09 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.878 | -1.675 | -2.404 | 1.054 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.833 | -5.715 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 13</span>| 483.13758 | 1.003 | -1.059 | -0.9067 | -0.9375 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9826 | -0.9029 | -0.2791 | -0.5415 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8881 | -1.081 | -0.5896 | -0.8508 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.053 | -0.5541 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 483.13758 | 91.30 | -5.259 | -0.8867 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.595 | 0.4505 | 1.077 | 0.06813 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7227 | 0.7157 | 1.512 | 0.9758 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7089 | 1.594 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 483.13758</span> | 91.30 | 0.005202 | 0.2918 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01010 | 0.6108 | 1.077 | 0.06813 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7227 | 0.7157 | 1.512 | 0.9758 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7089 | 1.594 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 16.83 | 1.368 | 0.7006 | 0.02276 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3159 | 0.7144 | 5.487 | 10.74 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.773 | -1.125 | -2.251 | 1.956 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.882 | -5.671 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 14</span>| 482.85180 | 0.9981 | -1.062 | -0.9072 | -0.9376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9834 | -0.9050 | -0.2850 | -0.5582 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8853 | -1.082 | -0.5852 | -0.8503 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.053 | -0.5428 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 482.8518 | 90.83 | -5.262 | -0.8872 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.596 | 0.4496 | 1.075 | 0.06764 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7248 | 0.7152 | 1.517 | 0.9762 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7084 | 1.607 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 482.8518</span> | 90.83 | 0.005184 | 0.2917 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01009 | 0.6105 | 1.075 | 0.06764 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7248 | 0.7152 | 1.517 | 0.9762 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7084 | 1.607 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -16.64 | 1.337 | 0.2421 | 0.09047 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3389 | 0.7643 | 5.051 | 10.06 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.787 | -1.445 | -2.047 | 2.073 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.627 | -5.410 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 15</span>| 482.60290 | 1.003 | -1.066 | -0.9079 | -0.9377 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9844 | -0.9075 | -0.2858 | -0.5723 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8822 | -1.083 | -0.5806 | -0.8571 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.055 | -0.5294 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 482.6029 | 91.28 | -5.266 | -0.8878 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.597 | 0.4484 | 1.074 | 0.06723 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7271 | 0.7136 | 1.523 | 0.9697 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7072 | 1.624 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 482.6029</span> | 91.28 | 0.005162 | 0.2916 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01008 | 0.6103 | 1.074 | 0.06723 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7271 | 0.7136 | 1.523 | 0.9697 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7072 | 1.624 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 14.50 | 1.352 | 0.6742 | 0.02192 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3317 | 0.7297 | 4.803 | 9.894 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.694 | -1.220 | -2.031 | 1.506 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.722 | -5.269 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 16</span>| 482.37953 | 0.9987 | -1.071 | -0.9090 | -0.9377 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9857 | -0.9106 | -0.2840 | -0.5862 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8787 | -1.084 | -0.5758 | -0.8611 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.056 | -0.5150 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 482.37953 | 90.88 | -5.271 | -0.8888 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.598 | 0.4470 | 1.075 | 0.06683 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7296 | 0.7132 | 1.528 | 0.9659 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7058 | 1.641 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 482.37953</span> | 90.88 | 0.005137 | 0.2914 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01007 | 0.6099 | 1.075 | 0.06683 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7296 | 0.7132 | 1.528 | 0.9659 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7058 | 1.641 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 17</span>| 482.17662 | 0.9986 | -1.077 | -0.9102 | -0.9378 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9871 | -0.9141 | -0.2800 | -0.5994 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8750 | -1.085 | -0.5707 | -0.8654 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.059 | -0.4996 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 482.17662 | 90.88 | -5.277 | -0.8898 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.600 | 0.4454 | 1.077 | 0.06645 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7323 | 0.7123 | 1.534 | 0.9618 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7037 | 1.660 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 482.17662</span> | 90.88 | 0.005108 | 0.2911 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01006 | 0.6095 | 1.077 | 0.06645 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7323 | 0.7123 | 1.534 | 0.9618 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7037 | 1.660 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 18</span>| 481.54428 | 0.9984 | -1.097 | -0.9142 | -0.9379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9921 | -0.9262 | -0.2660 | -0.6456 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8623 | -1.088 | -0.5530 | -0.8805 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.068 | -0.4457 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 481.54428 | 90.86 | -5.297 | -0.8934 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.605 | 0.4398 | 1.083 | 0.06511 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7417 | 0.7091 | 1.555 | 0.9473 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6961 | 1.725 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 481.54428</span> | 90.86 | 0.005009 | 0.2904 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01001 | 0.6082 | 1.083 | 0.06511 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7417 | 0.7091 | 1.555 | 0.9473 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6961 | 1.725 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 19</span>| 480.42060 | 0.9980 | -1.149 | -0.9249 | -0.9384 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.006 | -0.9588 | -0.2285 | -0.7695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8280 | -1.098 | -0.5055 | -0.9211 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.091 | -0.3011 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.4206 | 90.81 | -5.349 | -0.9029 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.618 | 0.4248 | 1.098 | 0.06151 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7667 | 0.7005 | 1.611 | 0.9085 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6759 | 1.901 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.4206</span> | 90.81 | 0.004753 | 0.2885 | 0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009872 | 0.6046 | 1.098 | 0.06151 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7667 | 0.7005 | 1.611 | 0.9085 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6759 | 1.901 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -36.54 | 1.160 | -0.4282 | 0.02550 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4248 | 0.7330 | 2.572 | 4.769 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.047 | -1.982 | 1.244 | -3.305 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.792 | -2.494 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 20</span>| 480.52888 | 1.003 | -1.232 | -0.9300 | -0.9345 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.037 | -1.013 | -0.2660 | -0.9542 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7770 | -1.021 | -0.6177 | -0.7306 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.035 | -0.1927 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.52888 | 91.28 | -5.432 | -0.9075 | -2.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.649 | 0.3997 | 1.083 | 0.05616 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8040 | 0.7699 | 1.479 | 1.091 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7247 | 2.033 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.52888</span> | 91.28 | 0.004374 | 0.2875 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009571 | 0.5986 | 1.083 | 0.05616 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8040 | 0.7699 | 1.479 | 1.091 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7247 | 2.033 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 21</span>| 479.69850 | 1.004 | -1.189 | -0.9273 | -0.9365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.020 | -0.9850 | -0.2467 | -0.8583 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8035 | -1.061 | -0.5593 | -0.8297 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.064 | -0.2490 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.6985 | 91.34 | -5.389 | -0.9050 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.633 | 0.4128 | 1.091 | 0.05894 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7846 | 0.7338 | 1.548 | 0.9959 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6994 | 1.964 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.6985</span> | 91.34 | 0.004567 | 0.2880 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009727 | 0.6018 | 1.091 | 0.05894 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7846 | 0.7338 | 1.548 | 0.9959 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6994 | 1.964 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.264 | 1.163 | -0.05494 | -0.06753 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3641 | 0.6248 | 0.1998 | 1.877 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5696 | 0.3809 | 0.8989 | 3.758 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2123 | -1.578 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 22</span>| 479.87893 | 1.001 | -1.256 | -0.9150 | -0.9312 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.045 | -1.024 | -0.2268 | -0.8946 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7799 | -1.052 | -0.6825 | -0.8629 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.056 | -0.2060 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.87893 | 91.06 | -5.456 | -0.8941 | -2.194 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.658 | 0.3949 | 1.099 | 0.05789 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8019 | 0.7416 | 1.402 | 0.9642 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7063 | 2.016 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.87893</span> | 91.06 | 0.004269 | 0.2903 | 0.1115 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009490 | 0.5975 | 1.099 | 0.05789 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8019 | 0.7416 | 1.402 | 0.9642 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7063 | 2.016 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 23</span>| 479.70356 | 0.9996 | -1.214 | -0.9229 | -0.9346 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.029 | -0.9992 | -0.2397 | -0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7947 | -1.058 | -0.6038 | -0.8437 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.061 | -0.2328 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.70356 | 90.96 | -5.414 | -0.9011 | -2.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.642 | 0.4062 | 1.093 | 0.05853 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7910 | 0.7364 | 1.495 | 0.9825 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7017 | 1.984 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.70356</span> | 90.96 | 0.004455 | 0.2888 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009639 | 0.6002 | 1.093 | 0.05853 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7910 | 0.7364 | 1.495 | 0.9825 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7017 | 1.984 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 24</span>| 479.71523 | 0.9993 | -1.201 | -0.9253 | -0.9356 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.025 | -0.9918 | -0.2436 | -0.8656 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7992 | -1.060 | -0.5801 | -0.8379 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.063 | -0.2408 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.71523 | 90.93 | -5.401 | -0.9032 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.637 | 0.4096 | 1.092 | 0.05873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7877 | 0.7349 | 1.523 | 0.9880 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7004 | 1.974 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.71523</span> | 90.93 | 0.004513 | 0.2884 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009685 | 0.6010 | 1.092 | 0.05873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7877 | 0.7349 | 1.523 | 0.9880 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.7004 | 1.974 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 25</span>| 479.73471 | 0.9991 | -1.194 | -0.9266 | -0.9362 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.022 | -0.9877 | -0.2457 | -0.8619 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8017 | -1.061 | -0.5670 | -0.8347 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.064 | -0.2453 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.73471 | 90.92 | -5.394 | -0.9044 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.635 | 0.4115 | 1.091 | 0.05884 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7859 | 0.7340 | 1.539 | 0.9911 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6996 | 1.969 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.73471</span> | 90.92 | 0.004545 | 0.2881 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009710 | 0.6015 | 1.091 | 0.05884 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7859 | 0.7340 | 1.539 | 0.9911 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6996 | 1.969 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 26</span>| 479.71271 | 1.001 | -1.190 | -0.9273 | -0.9365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.021 | -0.9854 | -0.2468 | -0.8594 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8032 | -1.061 | -0.5599 | -0.8320 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.064 | -0.2481 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.71271 | 91.05 | -5.390 | -0.9050 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.633 | 0.4126 | 1.091 | 0.05891 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7849 | 0.7336 | 1.547 | 0.9937 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6993 | 1.965 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.71271</span> | 91.05 | 0.004564 | 0.2880 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009725 | 0.6017 | 1.091 | 0.05891 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7849 | 0.7336 | 1.547 | 0.9937 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6993 | 1.965 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 27</span>| 479.69386 | 1.003 | -1.189 | -0.9273 | -0.9365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.020 | -0.9851 | -0.2467 | -0.8587 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8034 | -1.061 | -0.5595 | -0.8305 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.064 | -0.2487 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.69386 | 91.24 | -5.389 | -0.9050 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.633 | 0.4127 | 1.091 | 0.05893 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7847 | 0.7338 | 1.548 | 0.9951 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6994 | 1.965 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.69386</span> | 91.24 | 0.004566 | 0.2880 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009726 | 0.6017 | 1.091 | 0.05893 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7847 | 0.7338 | 1.548 | 0.9951 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6994 | 1.965 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.722 | 1.155 | -0.1645 | -0.05121 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3669 | 0.6376 | 0.06785 | 1.772 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5854 | 0.2936 | 0.9229 | 3.709 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2520 | -1.579 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 28</span>| 479.68901 | 1.004 | -1.189 | -0.9273 | -0.9365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.021 | -0.9853 | -0.2467 | -0.8591 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8033 | -1.061 | -0.5597 | -0.8314 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.064 | -0.2483 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.68901 | 91.32 | -5.389 | -0.9050 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.633 | 0.4126 | 1.091 | 0.05892 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7848 | 0.7337 | 1.547 | 0.9942 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6993 | 1.965 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.68901</span> | 91.32 | 0.004565 | 0.2880 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009725 | 0.6017 | 1.091 | 0.05892 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7848 | 0.7337 | 1.547 | 0.9942 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6993 | 1.965 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.772 | 1.160 | -0.07003 | -0.06455 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3646 | 0.6238 | 0.08418 | 1.806 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5672 | 0.3711 | 0.9250 | 3.651 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2161 | -1.579 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 29</span>| 479.68474 | 1.003 | -1.190 | -0.9272 | -0.9365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.021 | -0.9854 | -0.2468 | -0.8595 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8031 | -1.061 | -0.5600 | -0.8323 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.064 | -0.2479 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.68474 | 91.24 | -5.390 | -0.9050 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.633 | 0.4126 | 1.091 | 0.05890 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7849 | 0.7336 | 1.547 | 0.9934 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6993 | 1.966 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.68474</span> | 91.24 | 0.004563 | 0.2880 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009724 | 0.6017 | 1.091 | 0.05890 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7849 | 0.7336 | 1.547 | 0.9934 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6993 | 1.966 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.834 | 1.153 | -0.1599 | -0.05010 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3669 | 0.6355 | 0.09191 | 1.764 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5796 | 0.2889 | 1.006 | 3.561 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2610 | -1.565 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 30</span>| 479.68016 | 1.004 | -1.190 | -0.9272 | -0.9365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.021 | -0.9856 | -0.2468 | -0.8600 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8030 | -1.061 | -0.5602 | -0.8332 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.064 | -0.2475 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.68016 | 91.32 | -5.390 | -0.9050 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.633 | 0.4125 | 1.091 | 0.05889 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7850 | 0.7336 | 1.547 | 0.9926 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6992 | 1.966 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.68016</span> | 91.32 | 0.004562 | 0.2880 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009723 | 0.6017 | 1.091 | 0.05889 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7850 | 0.7336 | 1.547 | 0.9926 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6992 | 1.966 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.891 | 1.158 | -0.06530 | -0.06447 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3645 | 0.6207 | 0.1821 | 1.812 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5486 | 0.3656 | 1.002 | 3.562 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2233 | -1.574 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 31</span>| 479.67614 | 1.003 | -1.190 | -0.9272 | -0.9365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.021 | -0.9857 | -0.2468 | -0.8604 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8028 | -1.061 | -0.5604 | -0.8341 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.064 | -0.2472 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.67614 | 91.24 | -5.390 | -0.9049 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.633 | 0.4124 | 1.091 | 0.05888 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7851 | 0.7335 | 1.546 | 0.9917 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6992 | 1.966 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.67614</span> | 91.24 | 0.004561 | 0.2880 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009722 | 0.6017 | 1.091 | 0.05888 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7851 | 0.7335 | 1.546 | 0.9917 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6992 | 1.966 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.915 | 1.151 | -0.1574 | -0.04977 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3672 | 0.6321 | 0.06058 | 1.705 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5691 | 0.2601 | 0.8724 | 3.420 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2638 | -1.562 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 32</span>| 479.67180 | 1.004 | -1.191 | -0.9271 | -0.9364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.021 | -0.9859 | -0.2469 | -0.8608 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8027 | -1.061 | -0.5607 | -0.8349 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.064 | -0.2468 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.6718 | 91.33 | -5.391 | -0.9049 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.633 | 0.4124 | 1.091 | 0.05887 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7852 | 0.7334 | 1.546 | 0.9909 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6991 | 1.967 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.6718</span> | 91.33 | 0.004560 | 0.2880 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009722 | 0.6017 | 1.091 | 0.05887 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7852 | 0.7334 | 1.546 | 0.9909 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6991 | 1.967 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.074 | 1.157 | -0.05990 | -0.06452 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3645 | 0.6170 | 0.1286 | 1.744 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5576 | 0.3161 | 0.9007 | 3.345 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2216 | -1.572 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 33</span>| 479.66809 | 1.003 | -1.191 | -0.9271 | -0.9364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.021 | -0.9860 | -0.2469 | -0.8613 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8026 | -1.062 | -0.5609 | -0.8357 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.064 | -0.2464 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.66809 | 91.23 | -5.391 | -0.9049 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.634 | 0.4123 | 1.091 | 0.05885 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7853 | 0.7334 | 1.546 | 0.9901 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6991 | 1.967 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.66809</span> | 91.23 | 0.004558 | 0.2880 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009721 | 0.6016 | 1.091 | 0.05885 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7853 | 0.7334 | 1.546 | 0.9901 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6991 | 1.967 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.161 | 1.149 | -0.1570 | -0.04911 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3674 | 0.6293 | 0.04215 | 1.668 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5621 | 0.2625 | 0.8940 | 3.313 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2611 | -1.561 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 34</span>| 479.66397 | 1.004 | -1.191 | -0.9271 | -0.9364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.021 | -0.9862 | -0.2469 | -0.8617 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8024 | -1.062 | -0.5611 | -0.8366 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.064 | -0.2460 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.66397 | 91.33 | -5.391 | -0.9049 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.634 | 0.4122 | 1.091 | 0.05884 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7854 | 0.7333 | 1.546 | 0.9893 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6990 | 1.968 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.66397</span> | 91.33 | 0.004557 | 0.2881 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009720 | 0.6016 | 1.091 | 0.05884 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7854 | 0.7333 | 1.546 | 0.9893 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6990 | 1.968 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.197 | 1.155 | -0.05534 | -0.06448 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3644 | 0.6140 | 0.1526 | 1.765 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5340 | 0.3555 | 0.9900 | 3.325 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2199 | -1.571 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 35</span>| 479.66043 | 1.003 | -1.191 | -0.9271 | -0.9364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.021 | -0.9863 | -0.2469 | -0.8621 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8023 | -1.062 | -0.5613 | -0.8374 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.064 | -0.2456 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.66043 | 91.23 | -5.391 | -0.9048 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.634 | 0.4122 | 1.090 | 0.05883 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7855 | 0.7332 | 1.545 | 0.9886 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6989 | 1.968 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.66043</span> | 91.23 | 0.004556 | 0.2881 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009719 | 0.6016 | 1.090 | 0.05883 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7855 | 0.7332 | 1.545 | 0.9886 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6989 | 1.968 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.161 | 1.147 | -0.1538 | -0.04891 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3674 | 0.6262 | 0.06581 | 1.677 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5453 | 0.2828 | 1.029 | 3.251 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2683 | -1.555 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 36</span>| 479.65652 | 1.004 | -1.192 | -0.9270 | -0.9364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.021 | -0.9865 | -0.2469 | -0.8625 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8022 | -1.062 | -0.5616 | -0.8382 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.064 | -0.2452 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.65652 | 91.33 | -5.392 | -0.9048 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.634 | 0.4121 | 1.090 | 0.05882 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7856 | 0.7332 | 1.545 | 0.9878 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6989 | 1.969 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.65652</span> | 91.33 | 0.004554 | 0.2881 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009718 | 0.6016 | 1.090 | 0.05882 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7856 | 0.7332 | 1.545 | 0.9878 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6989 | 1.969 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.221 | 1.153 | -0.05203 | -0.06424 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3643 | 0.6104 | 0.04854 | 1.680 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5365 | 0.2999 | 0.7877 | 3.080 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2284 | -1.566 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 37</span>| 479.65328 | 1.003 | -1.192 | -0.9270 | -0.9364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.021 | -0.9866 | -0.2470 | -0.8629 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8020 | -1.062 | -0.5618 | -0.8389 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.064 | -0.2448 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.65328 | 91.23 | -5.392 | -0.9048 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.634 | 0.4120 | 1.090 | 0.05880 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7857 | 0.7331 | 1.545 | 0.9871 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6988 | 1.969 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.65328</span> | 91.23 | 0.004553 | 0.2881 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009717 | 0.6016 | 1.090 | 0.05880 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7857 | 0.7331 | 1.545 | 0.9871 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6988 | 1.969 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.438 | 1.145 | -0.1538 | -0.04822 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3675 | 0.6235 | 0.0004265 | 1.625 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5487 | 0.2329 | 0.8499 | 3.058 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2658 | -1.554 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 38</span>| 479.64923 | 1.004 | -1.192 | -0.9270 | -0.9364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.022 | -0.9868 | -0.2469 | -0.8633 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8019 | -1.062 | -0.5621 | -0.8396 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.065 | -0.2444 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.64923 | 91.32 | -5.392 | -0.9048 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.634 | 0.4119 | 1.091 | 0.05879 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7858 | 0.7330 | 1.544 | 0.9864 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6988 | 1.970 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.64923</span> | 91.32 | 0.004551 | 0.2881 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009716 | 0.6015 | 1.091 | 0.05879 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7858 | 0.7330 | 1.544 | 0.9864 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6988 | 1.970 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.878 | 1.150 | -0.05277 | -0.06333 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3643 | 0.6074 | 0.07271 | 1.651 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5369 | 0.2992 | 0.8896 | 2.970 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2314 | -1.562 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 39</span>| 479.64621 | 1.003 | -1.193 | -0.9270 | -0.9363 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.022 | -0.9870 | -0.2469 | -0.8638 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8017 | -1.062 | -0.5623 | -0.8404 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.065 | -0.2440 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.64621 | 91.23 | -5.393 | -0.9047 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.634 | 0.4119 | 1.091 | 0.05878 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7859 | 0.7330 | 1.544 | 0.9856 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6987 | 1.970 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.64621</span> | 91.23 | 0.004550 | 0.2881 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009715 | 0.6015 | 1.091 | 0.05878 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7859 | 0.7330 | 1.544 | 0.9856 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6987 | 1.970 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.471 | 1.143 | -0.1506 | -0.04802 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3674 | 0.6203 | -0.003354 | 1.603 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5429 | 0.2243 | 0.9025 | 2.920 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2732 | -1.548 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 40</span>| 479.64228 | 1.004 | -1.193 | -0.9269 | -0.9363 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.022 | -0.9872 | -0.2468 | -0.8642 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8016 | -1.062 | -0.5627 | -0.8411 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.065 | -0.2435 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.64228 | 91.32 | -5.393 | -0.9047 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.634 | 0.4118 | 1.091 | 0.05877 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7860 | 0.7329 | 1.544 | 0.9850 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6987 | 1.971 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.64228</span> | 91.32 | 0.004548 | 0.2881 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009714 | 0.6015 | 1.091 | 0.05877 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7860 | 0.7329 | 1.544 | 0.9850 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6987 | 1.971 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.744 | 1.148 | -0.05088 | -0.06289 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3642 | 0.6037 | 0.03047 | 1.629 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5287 | 0.2733 | 0.8334 | 2.850 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2290 | -1.558 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 41</span>| 479.63935 | 1.003 | -1.193 | -0.9269 | -0.9363 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.022 | -0.9874 | -0.2468 | -0.8646 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8014 | -1.062 | -0.5630 | -0.8419 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.065 | -0.2431 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.63935 | 91.23 | -5.393 | -0.9047 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.634 | 0.4117 | 1.091 | 0.05876 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7861 | 0.7329 | 1.543 | 0.9843 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6986 | 1.971 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.63935</span> | 91.23 | 0.004547 | 0.2881 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009713 | 0.6015 | 1.091 | 0.05876 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7861 | 0.7329 | 1.543 | 0.9843 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6986 | 1.971 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.432 | 1.140 | -0.1464 | -0.04798 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3672 | 0.6157 | -0.06295 | 1.547 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5341 | 0.1919 | 0.7582 | 2.801 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2698 | -1.544 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 42</span>| 479.63543 | 1.004 | -1.194 | -0.9268 | -0.9363 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.022 | -0.9876 | -0.2467 | -0.8650 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8013 | -1.062 | -0.5633 | -0.8425 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.065 | -0.2426 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.63543 | 91.32 | -5.394 | -0.9046 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.634 | 0.4116 | 1.091 | 0.05874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7863 | 0.7328 | 1.543 | 0.9837 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6985 | 1.972 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.63543</span> | 91.32 | 0.004545 | 0.2881 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009712 | 0.6015 | 1.091 | 0.05874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7863 | 0.7328 | 1.543 | 0.9837 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6985 | 1.972 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.612 | 1.146 | -0.04876 | -0.06242 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3640 | 0.6002 | 0.04743 | 1.619 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5199 | 0.2573 | 0.7734 | 2.739 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2298 | -1.553 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 43</span>| 479.63248 | 1.003 | -1.194 | -0.9268 | -0.9363 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.022 | -0.9878 | -0.2466 | -0.8655 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8011 | -1.062 | -0.5636 | -0.8432 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.065 | -0.2421 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.63248 | 91.23 | -5.394 | -0.9046 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.635 | 0.4115 | 1.091 | 0.05873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7864 | 0.7328 | 1.543 | 0.9830 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6985 | 1.973 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.63248</span> | 91.23 | 0.004543 | 0.2881 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009710 | 0.6014 | 1.091 | 0.05873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7864 | 0.7328 | 1.543 | 0.9830 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6985 | 1.973 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.237 | 1.138 | -0.1400 | -0.04830 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3668 | 0.6108 | -0.07665 | 1.521 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5353 | 0.1893 | 0.7456 | 2.704 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2668 | -1.543 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 44</span>| 479.62869 | 1.004 | -1.195 | -0.9268 | -0.9362 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.022 | -0.9880 | -0.2464 | -0.8659 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8009 | -1.062 | -0.5639 | -0.8438 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.065 | -0.2415 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.62869 | 91.32 | -5.395 | -0.9046 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.635 | 0.4114 | 1.091 | 0.05872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7865 | 0.7327 | 1.542 | 0.9824 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6984 | 1.973 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.62869</span> | 91.32 | 0.004541 | 0.2881 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009709 | 0.6014 | 1.091 | 0.05872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7865 | 0.7327 | 1.542 | 0.9824 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6984 | 1.973 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.552 | 1.143 | -0.04554 | -0.06221 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3637 | 0.5952 | -0.01323 | 1.563 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3448 | 0.2470 | 0.7924 | 2.643 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2272 | -1.550 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 45</span>| 479.62584 | 1.003 | -1.195 | -0.9268 | -0.9362 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.022 | -0.9883 | -0.2463 | -0.8663 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8008 | -1.062 | -0.5642 | -0.8446 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.065 | -0.2410 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.62584 | 91.24 | -5.395 | -0.9046 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.635 | 0.4113 | 1.091 | 0.05871 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7866 | 0.7326 | 1.542 | 0.9817 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6983 | 1.974 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.62584</span> | 91.24 | 0.004539 | 0.2881 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009708 | 0.6014 | 1.091 | 0.05871 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7866 | 0.7326 | 1.542 | 0.9817 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6983 | 1.974 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.148 | 1.135 | -0.1348 | -0.04846 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3664 | 0.6063 | -0.009834 | 1.510 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5271 | 0.1803 | 0.7932 | 2.587 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2684 | -1.536 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 46</span>| 479.62216 | 1.004 | -1.195 | -0.9267 | -0.9362 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.023 | -0.9885 | -0.2462 | -0.8667 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8007 | -1.062 | -0.5646 | -0.8451 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.065 | -0.2404 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.62216 | 91.32 | -5.395 | -0.9045 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.635 | 0.4112 | 1.091 | 0.05870 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7867 | 0.7326 | 1.541 | 0.9811 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6983 | 1.975 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.62216</span> | 91.32 | 0.004537 | 0.2881 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009706 | 0.6014 | 1.091 | 0.05870 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7867 | 0.7326 | 1.541 | 0.9811 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6983 | 1.975 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.404 | 1.140 | -0.04564 | -0.06187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3633 | 0.5903 | -0.01970 | 1.541 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5054 | 0.2303 | 0.6483 | 2.528 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2288 | -1.542 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 47</span>| 479.61938 | 1.003 | -1.196 | -0.9267 | -0.9362 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.023 | -0.9887 | -0.2461 | -0.8672 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8005 | -1.062 | -0.5649 | -0.8458 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.065 | -0.2398 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.61938 | 91.24 | -5.396 | -0.9045 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.635 | 0.4111 | 1.091 | 0.05868 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7868 | 0.7325 | 1.541 | 0.9805 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6982 | 1.975 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.61938</span> | 91.24 | 0.004535 | 0.2881 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009705 | 0.6013 | 1.091 | 0.05868 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7868 | 0.7325 | 1.541 | 0.9805 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6982 | 1.975 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.197 | 1.132 | -0.1312 | -0.04839 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3660 | 0.6012 | 0.05916 | 1.560 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4869 | 0.2015 | 0.8305 | 2.573 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2666 | -1.531 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 48</span>| 479.61563 | 1.003 | -1.196 | -0.9266 | -0.9361 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.023 | -0.9890 | -0.2459 | -0.8676 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8003 | -1.062 | -0.5653 | -0.8464 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.065 | -0.2392 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.61563 | 91.32 | -5.396 | -0.9044 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.635 | 0.4109 | 1.091 | 0.05867 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7870 | 0.7325 | 1.541 | 0.9799 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6981 | 1.976 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.61563</span> | 91.32 | 0.004533 | 0.2881 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009703 | 0.6013 | 1.091 | 0.05867 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7870 | 0.7325 | 1.541 | 0.9799 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6981 | 1.976 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.024 | 1.137 | -0.04591 | -0.06118 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3629 | 0.5856 | 0.004035 | 1.536 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4978 | 0.2329 | 0.6617 | 2.436 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2318 | -1.535 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 49</span>| 479.61337 | 1.003 | -1.197 | -0.9266 | -0.9361 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.023 | -0.9892 | -0.2459 | -0.8680 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8001 | -1.063 | -0.5655 | -0.8471 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.065 | -0.2388 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.61337 | 91.23 | -5.397 | -0.9044 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.635 | 0.4109 | 1.091 | 0.05866 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7871 | 0.7324 | 1.540 | 0.9792 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6980 | 1.977 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.61337</span> | 91.23 | 0.004531 | 0.2881 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009702 | 0.6013 | 1.091 | 0.05866 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7871 | 0.7324 | 1.540 | 0.9792 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6980 | 1.977 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.815 | 1.129 | -0.1342 | -0.04706 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3660 | 0.5971 | -0.07697 | 1.438 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5059 | 0.1462 | 0.6633 | 2.381 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2676 | -1.522 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 50</span>| 479.60932 | 1.003 | -1.197 | -0.9266 | -0.9361 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.023 | -0.9894 | -0.2456 | -0.8684 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8000 | -1.063 | -0.5659 | -0.8476 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.066 | -0.2381 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.60932 | 91.31 | -5.397 | -0.9044 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.636 | 0.4107 | 1.091 | 0.05865 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7872 | 0.7324 | 1.540 | 0.9788 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6979 | 1.977 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.60932</span> | 91.31 | 0.004529 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009700 | 0.6013 | 1.091 | 0.05865 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7872 | 0.7324 | 1.540 | 0.9788 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6979 | 1.977 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.699 | 1.134 | -0.04549 | -0.06017 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3630 | 0.5814 | -0.04512 | 1.484 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4915 | 0.2556 | 0.7248 | 2.322 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2317 | -1.529 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 51</span>| 479.60706 | 1.003 | -1.198 | -0.9265 | -0.9361 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.023 | -0.9896 | -0.2455 | -0.8689 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7998 | -1.063 | -0.5661 | -0.8484 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.066 | -0.2376 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.60706 | 91.23 | -5.398 | -0.9044 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.636 | 0.4106 | 1.091 | 0.05863 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7873 | 0.7323 | 1.540 | 0.9781 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6979 | 1.978 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.60706</span> | 91.23 | 0.004527 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009699 | 0.6012 | 1.091 | 0.05863 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7873 | 0.7323 | 1.540 | 0.9781 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6979 | 1.978 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.618 | 1.127 | -0.1276 | -0.04760 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3656 | 0.5915 | -0.08622 | 1.415 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5531 | 0.1512 | 0.6569 | 2.298 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2620 | -1.540 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 52</span>| 479.60314 | 1.003 | -1.198 | -0.9265 | -0.9360 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.023 | -0.9899 | -0.2452 | -0.8692 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7996 | -1.063 | -0.5665 | -0.8488 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.066 | -0.2369 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.60314 | 91.31 | -5.398 | -0.9043 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.636 | 0.4105 | 1.091 | 0.05862 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7875 | 0.7322 | 1.539 | 0.9776 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6978 | 1.979 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.60314</span> | 91.31 | 0.004525 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009698 | 0.6012 | 1.091 | 0.05862 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7875 | 0.7322 | 1.539 | 0.9776 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6978 | 1.979 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.641 | 1.131 | -0.04213 | -0.06002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3627 | 0.5770 | -0.05114 | 1.464 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4913 | 0.1735 | 0.5980 | 2.238 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2116 | -1.521 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 53</span>| 479.60093 | 1.003 | -1.199 | -0.9265 | -0.9360 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.024 | -0.9901 | -0.2452 | -0.8697 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7994 | -1.063 | -0.5667 | -0.8495 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.066 | -0.2363 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.60093 | 91.23 | -5.399 | -0.9043 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.636 | 0.4104 | 1.091 | 0.05861 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7876 | 0.7322 | 1.539 | 0.9769 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6977 | 1.980 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.60093</span> | 91.23 | 0.004523 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009696 | 0.6012 | 1.091 | 0.05861 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7876 | 0.7322 | 1.539 | 0.9769 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6977 | 1.980 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.657 | 1.124 | -0.1240 | -0.04721 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3655 | 0.5872 | -0.09119 | 1.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4948 | 0.1646 | 0.6965 | 2.186 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2747 | -1.512 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 54</span>| 479.59701 | 1.003 | -1.199 | -0.9264 | -0.9360 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.024 | -0.9904 | -0.2448 | -0.8700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7992 | -1.063 | -0.5670 | -0.8499 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.066 | -0.2356 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.59701 | 91.31 | -5.399 | -0.9043 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.636 | 0.4103 | 1.091 | 0.05860 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7877 | 0.7321 | 1.539 | 0.9766 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6976 | 1.980 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.59701</span> | 91.31 | 0.004520 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009695 | 0.6012 | 1.091 | 0.05860 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7877 | 0.7321 | 1.539 | 0.9766 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6976 | 1.980 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.447 | 1.128 | -0.03826 | -0.05934 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3628 | 0.5721 | -0.04376 | 1.440 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4844 | 0.2233 | -0.3355 | 1.410 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3677 | -1.539 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 55</span>| 479.59436 | 1.003 | -1.200 | -0.9264 | -0.9360 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.024 | -0.9907 | -0.2446 | -0.8705 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7990 | -1.063 | -0.5669 | -0.8504 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.066 | -0.2349 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.59436 | 91.23 | -5.400 | -0.9042 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.636 | 0.4102 | 1.091 | 0.05858 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7879 | 0.7320 | 1.539 | 0.9761 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6977 | 1.981 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.59436</span> | 91.23 | 0.004518 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009693 | 0.6011 | 1.091 | 0.05858 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7879 | 0.7320 | 1.539 | 0.9761 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6977 | 1.981 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.478 | 1.121 | -0.1165 | -0.04761 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3651 | 0.5835 | -0.09604 | 1.373 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4943 | 0.1086 | -0.4551 | 1.395 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3088 | -1.502 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 56</span>| 479.58979 | 1.003 | -1.200 | -0.9263 | -0.9359 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.024 | -0.9910 | -0.2442 | -0.8708 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7988 | -1.063 | -0.5665 | -0.8506 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.066 | -0.2341 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.58979 | 91.30 | -5.400 | -0.9042 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.637 | 0.4100 | 1.092 | 0.05858 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7880 | 0.7319 | 1.539 | 0.9759 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6978 | 1.982 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.58979</span> | 91.30 | 0.004516 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009691 | 0.6011 | 1.092 | 0.05858 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7880 | 0.7319 | 1.539 | 0.9759 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6978 | 1.982 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.813 | 1.125 | -0.03904 | -0.05862 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3624 | 0.5728 | -0.008587 | 1.448 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2657 | 0.1639 | 0.6610 | 2.108 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2622 | -1.501 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 57</span>| 479.58727 | 1.003 | -1.201 | -0.9263 | -0.9359 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.024 | -0.9912 | -0.2441 | -0.8713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7987 | -1.063 | -0.5668 | -0.8514 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.066 | -0.2335 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.58727 | 91.24 | -5.401 | -0.9042 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.637 | 0.4099 | 1.092 | 0.05856 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7881 | 0.7318 | 1.539 | 0.9751 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6978 | 1.983 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.58727</span> | 91.24 | 0.004513 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009690 | 0.6011 | 1.092 | 0.05856 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7881 | 0.7318 | 1.539 | 0.9751 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6978 | 1.983 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.987 | 1.119 | -0.1055 | -0.04878 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3644 | 0.5797 | -0.03160 | 1.359 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4809 | 0.09403 | -0.4184 | 1.337 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2770 | -1.489 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 58</span>| 479.58366 | 1.004 | -1.201 | -0.9263 | -0.9359 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.024 | -0.9915 | -0.2438 | -0.8717 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7986 | -1.063 | -0.5667 | -0.8517 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.066 | -0.2327 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.58366 | 91.32 | -5.401 | -0.9041 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.637 | 0.4098 | 1.092 | 0.05855 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7882 | 0.7317 | 1.539 | 0.9749 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6978 | 1.984 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.58366</span> | 91.32 | 0.004511 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009688 | 0.6010 | 1.092 | 0.05855 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7882 | 0.7317 | 1.539 | 0.9749 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6978 | 1.984 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.434 | 1.122 | -0.01954 | -0.06326 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3597 | 0.5645 | -0.03484 | 1.404 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4782 | 0.1697 | -0.05991 | 1.573 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2504 | -1.489 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 59</span>| 479.57994 | 1.003 | -1.202 | -0.9262 | -0.9358 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.025 | -0.9918 | -0.2433 | -0.8720 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7984 | -1.063 | -0.5664 | -0.8520 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.066 | -0.2319 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.57994 | 91.26 | -5.402 | -0.9041 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.637 | 0.4096 | 1.092 | 0.05854 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7884 | 0.7316 | 1.539 | 0.9746 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6977 | 1.985 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.57994</span> | 91.26 | 0.004508 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009686 | 0.6010 | 1.092 | 0.05854 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7884 | 0.7316 | 1.539 | 0.9746 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6977 | 1.985 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.328 | 1.117 | -0.07952 | -0.05137 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3636 | 0.5738 | 0.02815 | 1.418 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4669 | 0.1345 | 0.7258 | 2.078 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2949 | -1.476 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 60</span>| 479.57683 | 1.004 | -1.202 | -0.9262 | -0.9358 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.025 | -0.9921 | -0.2431 | -0.8724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7982 | -1.064 | -0.5667 | -0.8526 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.066 | -0.2311 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.57683 | 91.32 | -5.402 | -0.9041 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.637 | 0.4095 | 1.092 | 0.05853 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7885 | 0.7315 | 1.539 | 0.9740 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6976 | 1.986 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.57683</span> | 91.32 | 0.004505 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009684 | 0.6010 | 1.092 | 0.05853 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7885 | 0.7315 | 1.539 | 0.9740 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6976 | 1.986 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.369 | 1.121 | -0.01236 | -0.06033 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3618 | 0.5608 | -0.009614 | 1.424 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4677 | 0.1416 | 0.6194 | 1.932 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2634 | -1.483 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 61</span>| 479.57433 | 1.003 | -1.203 | -0.9262 | -0.9358 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.025 | -0.9924 | -0.2429 | -0.8728 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7980 | -1.064 | -0.5671 | -0.8530 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.066 | -0.2304 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.57433 | 91.25 | -5.403 | -0.9041 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.637 | 0.4094 | 1.092 | 0.05852 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7886 | 0.7315 | 1.539 | 0.9736 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6975 | 1.987 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.57433</span> | 91.25 | 0.004503 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009683 | 0.6009 | 1.092 | 0.05852 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7886 | 0.7315 | 1.539 | 0.9736 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6975 | 1.987 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.507 | 1.111 | -0.09183 | -0.05192 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3614 | 0.5665 | -0.03887 | 1.349 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4753 | 0.07826 | 0.5528 | 1.905 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2844 | -1.468 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 62</span>| 479.57116 | 1.003 | -1.204 | -0.9262 | -0.9357 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.025 | -0.9927 | -0.2425 | -0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7978 | -1.064 | -0.5674 | -0.8534 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.066 | -0.2297 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.57116 | 91.32 | -5.404 | -0.9040 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.638 | 0.4092 | 1.092 | 0.05851 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7888 | 0.7315 | 1.538 | 0.9732 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6973 | 1.988 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.57116</span> | 91.32 | 0.004500 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009681 | 0.6009 | 1.092 | 0.05851 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7888 | 0.7315 | 1.538 | 0.9732 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6973 | 1.988 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.953 | 1.117 | -0.01332 | -0.05913 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3618 | 0.5550 | -0.01942 | 1.377 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4588 | 0.1396 | 0.5378 | 1.901 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2564 | -1.475 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 63</span>| 479.56857 | 1.003 | -1.204 | -0.9261 | -0.9357 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.025 | -0.9930 | -0.2422 | -0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7976 | -1.064 | -0.5677 | -0.8539 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.066 | -0.2289 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.56857 | 91.25 | -5.404 | -0.9040 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.638 | 0.4091 | 1.092 | 0.05850 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7889 | 0.7314 | 1.538 | 0.9728 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6972 | 1.989 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.56857</span> | 91.25 | 0.004497 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009679 | 0.6009 | 1.092 | 0.05850 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7889 | 0.7314 | 1.538 | 0.9728 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6972 | 1.989 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.279 | 1.109 | -0.08378 | -0.05051 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3625 | 0.5609 | -0.06234 | 1.320 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5093 | 0.06989 | -1.266 | 1.852 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2753 | -1.463 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 64</span>| 479.56430 | 1.003 | -1.205 | -0.9261 | -0.9357 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.9933 | -0.2419 | -0.8738 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7974 | -1.064 | -0.5672 | -0.8543 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2281 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.5643 | 91.31 | -5.405 | -0.9040 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.638 | 0.4090 | 1.093 | 0.05849 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7891 | 0.7314 | 1.538 | 0.9724 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6971 | 1.990 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.5643</span> | 91.31 | 0.004495 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009677 | 0.6008 | 1.093 | 0.05849 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7891 | 0.7314 | 1.538 | 0.9724 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6971 | 1.990 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.181 | 1.113 | -0.01711 | -0.05862 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3610 | 0.5490 | -0.06295 | 1.399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4495 | 0.1474 | 0.6781 | 1.913 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2455 | -1.468 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 65</span>| 479.56239 | 1.003 | -1.205 | -0.9261 | -0.9356 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.9935 | -0.2417 | -0.8744 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7972 | -1.064 | -0.5674 | -0.8549 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2275 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.56239 | 91.24 | -5.405 | -0.9040 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.638 | 0.4089 | 1.093 | 0.05847 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7892 | 0.7313 | 1.538 | 0.9718 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6970 | 1.990 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.56239</span> | 91.24 | 0.004493 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009675 | 0.6008 | 1.093 | 0.05847 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7892 | 0.7313 | 1.538 | 0.9718 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6970 | 1.990 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.516 | 1.106 | -0.09308 | -0.04714 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3636 | 0.5580 | -0.04406 | 1.488 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4662 | 0.05187 | 0.6104 | 1.787 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2769 | -1.453 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 66</span>| 479.55877 | 1.003 | -1.206 | -0.9261 | -0.9356 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.9938 | -0.2414 | -0.8747 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7970 | -1.064 | -0.5678 | -0.8553 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2268 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.55877 | 91.31 | -5.406 | -0.9039 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.638 | 0.4087 | 1.093 | 0.05846 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7894 | 0.7313 | 1.538 | 0.9714 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6969 | 1.991 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.55877</span> | 91.31 | 0.004490 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009674 | 0.6008 | 1.093 | 0.05846 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7894 | 0.7313 | 1.538 | 0.9714 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6969 | 1.991 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.254 | 1.111 | -0.01255 | -0.05783 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3613 | 0.5437 | -0.01079 | 1.366 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4954 | 0.1048 | 0.5565 | 1.745 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2417 | -1.458 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 67</span>| 479.55696 | 1.003 | -1.206 | -0.9261 | -0.9356 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.9940 | -0.2413 | -0.8753 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7968 | -1.064 | -0.5681 | -0.8559 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2262 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.55696 | 91.24 | -5.406 | -0.9039 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.639 | 0.4086 | 1.093 | 0.05845 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7895 | 0.7312 | 1.537 | 0.9708 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6968 | 1.992 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.55696</span> | 91.24 | 0.004488 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009672 | 0.6008 | 1.093 | 0.05845 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7895 | 0.7312 | 1.537 | 0.9708 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6968 | 1.992 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.420 | 1.104 | -0.08938 | -0.04652 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3638 | 0.5524 | -0.03600 | 1.474 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4537 | 0.08714 | 0.5943 | 1.686 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2777 | -1.443 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 68</span>| 479.55331 | 1.003 | -1.207 | -0.9260 | -0.9356 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.9943 | -0.2409 | -0.8756 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7966 | -1.064 | -0.5684 | -0.8562 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2254 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.55331 | 91.31 | -5.407 | -0.9039 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.639 | 0.4085 | 1.093 | 0.05844 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7897 | 0.7312 | 1.537 | 0.9706 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6966 | 1.993 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.55331</span> | 91.31 | 0.004485 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009670 | 0.6007 | 1.093 | 0.05844 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7897 | 0.7312 | 1.537 | 0.9706 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6966 | 1.993 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.940 | 1.107 | -0.01326 | -0.05734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3610 | 0.5380 | -0.03050 | 1.334 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4419 | 0.09953 | 0.4758 | 1.660 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2363 | -1.448 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 69</span>| 479.55178 | 1.003 | -1.208 | -0.9260 | -0.9355 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.9945 | -0.2409 | -0.8762 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7964 | -1.064 | -0.5686 | -0.8569 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2248 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.55178 | 91.23 | -5.408 | -0.9039 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.639 | 0.4084 | 1.093 | 0.05842 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7898 | 0.7311 | 1.537 | 0.9699 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6965 | 1.994 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.55178</span> | 91.23 | 0.004483 | 0.2882 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009668 | 0.6007 | 1.093 | 0.05842 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7898 | 0.7311 | 1.537 | 0.9699 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6965 | 1.994 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.846 | 1.100 | -0.09130 | -0.04553 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3638 | 0.5474 | -0.02936 | 1.430 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4494 | 0.05105 | 0.6245 | 1.611 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2724 | -1.435 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 70</span>| 479.54790 | 1.003 | -1.208 | -0.9260 | -0.9355 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.9948 | -0.2405 | -0.8765 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7962 | -1.064 | -0.5690 | -0.8571 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2240 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.5479 | 91.30 | -5.408 | -0.9039 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.639 | 0.4083 | 1.093 | 0.05841 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7899 | 0.7311 | 1.536 | 0.9697 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6964 | 1.995 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.5479</span> | 91.30 | 0.004480 | 0.2883 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009667 | 0.6007 | 1.093 | 0.05841 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7899 | 0.7311 | 1.536 | 0.9697 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6964 | 1.995 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.570 | 1.104 | -0.01594 | -0.05674 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3607 | 0.5327 | -0.02577 | 1.253 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4401 | 0.07544 | -0.5163 | 0.8741 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3456 | -1.445 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 71</span>| 479.54587 | 1.003 | -1.209 | -0.9260 | -0.9355 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.9951 | -0.2405 | -0.8771 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7960 | -1.064 | -0.5687 | -0.8576 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2233 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.54587 | 91.23 | -5.409 | -0.9039 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.639 | 0.4081 | 1.093 | 0.05839 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7901 | 0.7310 | 1.537 | 0.9693 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6965 | 1.995 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.54587</span> | 91.23 | 0.004478 | 0.2883 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009665 | 0.6006 | 1.093 | 0.05839 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7901 | 0.7310 | 1.537 | 0.9693 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6965 | 1.995 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.902 | 1.097 | -0.08880 | -0.04568 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3633 | 0.5436 | -0.03820 | 1.421 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4438 | 0.04451 | 0.5507 | 1.558 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2862 | -1.423 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 72</span>| 479.54157 | 1.003 | -1.209 | -0.9260 | -0.9354 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.9954 | -0.2399 | -0.8773 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7958 | -1.064 | -0.5687 | -0.8577 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2225 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.54157 | 91.30 | -5.409 | -0.9038 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.639 | 0.4080 | 1.093 | 0.05839 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7902 | 0.7309 | 1.537 | 0.9691 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6965 | 1.996 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.54157</span> | 91.30 | 0.004475 | 0.2883 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009663 | 0.6006 | 1.093 | 0.05839 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7902 | 0.7309 | 1.537 | 0.9691 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6965 | 1.996 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.063 | 1.100 | -0.01768 | -0.05631 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3603 | 0.5311 | -0.05904 | 1.468 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4400 | 0.06384 | 0.5216 | 1.564 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2548 | -1.433 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 73</span>| 479.53906 | 1.003 | -1.210 | -0.9259 | -0.9354 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.9956 | -0.2399 | -0.8780 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7956 | -1.064 | -0.5689 | -0.8584 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2218 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.53906 | 91.25 | -5.410 | -0.9038 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.640 | 0.4079 | 1.093 | 0.05837 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7904 | 0.7309 | 1.536 | 0.9684 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6964 | 1.997 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.53906</span> | 91.25 | 0.004472 | 0.2883 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009661 | 0.6006 | 1.093 | 0.05837 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7904 | 0.7309 | 1.536 | 0.9684 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6964 | 1.997 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.131 | 1.095 | -0.06506 | -0.04908 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3620 | 0.5356 | -0.007514 | 1.441 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4274 | 0.08578 | -0.3543 | 0.8441 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2944 | -1.418 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 74</span>| 479.53616 | 1.004 | -1.210 | -0.9259 | -0.9354 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.027 | -0.9959 | -0.2396 | -0.8785 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7954 | -1.064 | -0.5688 | -0.8586 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2210 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.53616 | 91.33 | -5.410 | -0.9038 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.640 | 0.4077 | 1.094 | 0.05835 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7905 | 0.7308 | 1.537 | 0.9682 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6965 | 1.998 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.53616</span> | 91.33 | 0.004470 | 0.2883 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009659 | 0.6005 | 1.094 | 0.05835 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7905 | 0.7308 | 1.537 | 0.9682 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6965 | 1.998 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.979 | 1.099 | 0.01619 | -0.06233 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3580 | 0.5217 | -0.09749 | 1.245 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4289 | 0.1115 | -0.5282 | 0.7580 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3266 | -1.417 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 75</span>| 479.53242 | 1.003 | -1.211 | -0.9259 | -0.9353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.028 | -0.9962 | -0.2391 | -0.8787 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7953 | -1.065 | -0.5685 | -0.8588 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2202 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.53242 | 91.27 | -5.411 | -0.9038 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.640 | 0.4076 | 1.094 | 0.05835 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7906 | 0.7307 | 1.537 | 0.9681 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6966 | 1.999 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.53242</span> | 91.27 | 0.004467 | 0.2883 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009657 | 0.6005 | 1.094 | 0.05835 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7906 | 0.7307 | 1.537 | 0.9681 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6966 | 1.999 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.679 | 1.093 | -0.04308 | -0.05224 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3605 | 0.5318 | -0.002555 | 1.446 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4215 | 0.05786 | 0.6079 | 1.538 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2997 | -1.401 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 76</span>| 479.52958 | 1.004 | -1.212 | -0.9259 | -0.9353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.028 | -0.9965 | -0.2388 | -0.8793 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7951 | -1.065 | -0.5686 | -0.8593 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2194 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.52958 | 91.33 | -5.412 | -0.9038 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.640 | 0.4075 | 1.094 | 0.05833 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7908 | 0.7306 | 1.537 | 0.9676 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6965 | 2.000 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.52958</span> | 91.33 | 0.004464 | 0.2883 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009655 | 0.6005 | 1.094 | 0.05833 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7908 | 0.7306 | 1.537 | 0.9676 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6965 | 2.000 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.139 | 1.094 | 0.01046 | -0.06226 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3570 | 0.5194 | -0.09592 | 1.421 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4323 | 0.06052 | -0.5454 | 0.7071 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2962 | -1.410 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 77</span>| 479.52646 | 1.003 | -1.212 | -0.9259 | -0.9353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.028 | -0.9968 | -0.2384 | -0.8797 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7949 | -1.065 | -0.5684 | -0.8594 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2186 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.52646 | 91.26 | -5.412 | -0.9038 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.640 | 0.4073 | 1.094 | 0.05832 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7909 | 0.7304 | 1.537 | 0.9675 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6966 | 2.001 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.52646</span> | 91.26 | 0.004461 | 0.2883 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009653 | 0.6005 | 1.094 | 0.05832 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7909 | 0.7304 | 1.537 | 0.9675 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6966 | 2.001 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.758 | 1.088 | -0.05217 | -0.05158 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3593 | 0.5291 | -0.05980 | 1.185 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4227 | -2.218 | -0.3659 | 0.8223 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2423 | -1.392 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 78</span>| 479.52294 | 1.003 | -1.213 | -0.9258 | -0.9352 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.028 | -0.9971 | -0.2379 | -0.8800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7947 | -1.064 | -0.5681 | -0.8596 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2178 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.52294 | 91.30 | -5.413 | -0.9037 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.641 | 0.4072 | 1.094 | 0.05831 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7910 | 0.7311 | 1.537 | 0.9673 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6967 | 2.002 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.52294</span> | 91.30 | 0.004458 | 0.2883 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009652 | 0.6004 | 1.094 | 0.05831 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7910 | 0.7311 | 1.537 | 0.9673 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6967 | 2.002 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 0.7571 | 1.091 | -0.01328 | -0.05733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3573 | 0.5211 | 0.006105 | 1.423 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4119 | 0.1268 | 0.6771 | 1.465 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.3146 | -1.386 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 79</span>| 479.52041 | 1.003 | -1.213 | -0.9258 | -0.9352 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.028 | -0.9973 | -0.2380 | -0.8807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7945 | -1.064 | -0.5684 | -0.8604 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2172 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.52041 | 91.27 | -5.413 | -0.9037 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.641 | 0.4071 | 1.094 | 0.05829 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7912 | 0.7311 | 1.537 | 0.9666 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6965 | 2.003 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.52041</span> | 91.27 | 0.004456 | 0.2883 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009650 | 0.6004 | 1.094 | 0.05829 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7912 | 0.7311 | 1.537 | 0.9666 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6965 | 2.003 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.400 | 1.087 | -0.04852 | -0.05189 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3585 | 0.5236 | -0.05100 | 1.183 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4319 | 0.01564 | 0.3566 | 1.324 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.3221 | -1.379 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 80</span>| 479.51911 | 1.004 | -1.214 | -0.9258 | -0.9352 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.029 | -0.9976 | -0.2379 | -0.8812 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7944 | -1.064 | -0.5686 | -0.8609 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2166 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.51911 | 91.35 | -5.414 | -0.9037 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.641 | 0.4070 | 1.094 | 0.05828 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7913 | 0.7310 | 1.537 | 0.9661 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6964 | 2.004 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.51911</span> | 91.35 | 0.004454 | 0.2883 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009648 | 0.6004 | 1.094 | 0.05828 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7913 | 0.7310 | 1.537 | 0.9661 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6964 | 2.004 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.458 | 1.092 | 0.04306 | -0.06507 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3552 | 0.5068 | -0.06807 | 1.418 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4090 | 0.1358 | -0.5109 | 0.5676 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2804 | -1.390 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 81</span>| 479.51487 | 1.003 | -1.215 | -0.9258 | -0.9352 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.029 | -0.9978 | -0.2377 | -0.8817 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7942 | -1.064 | -0.5685 | -0.8612 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2158 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.51487 | 91.27 | -5.415 | -0.9037 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.641 | 0.4069 | 1.094 | 0.05826 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7914 | 0.7307 | 1.537 | 0.9658 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6963 | 2.005 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.51487</span> | 91.27 | 0.004451 | 0.2883 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009647 | 0.6003 | 1.094 | 0.05826 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7914 | 0.7307 | 1.537 | 0.9658 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6963 | 2.005 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.582 | 1.084 | -0.03533 | -0.05340 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3581 | 0.5175 | -0.06480 | 1.157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4224 | 0.03489 | -0.5536 | 0.6041 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2386 | -1.371 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 82</span>| 479.51208 | 1.004 | -1.215 | -0.9258 | -0.9351 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.029 | -0.9981 | -0.2375 | -0.8823 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7939 | -1.065 | -0.5682 | -0.8615 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2150 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.51208 | 91.34 | -5.415 | -0.9037 | -2.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.641 | 0.4067 | 1.094 | 0.05824 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7916 | 0.7306 | 1.537 | 0.9655 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6964 | 2.006 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.51208</span> | 91.34 | 0.004449 | 0.2883 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009645 | 0.6003 | 1.094 | 0.05824 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7916 | 0.7306 | 1.537 | 0.9655 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6964 | 2.006 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.943 | 1.087 | 0.02817 | -0.06279 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3555 | 0.5065 | -0.06060 | 1.305 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4115 | 0.06912 | 0.4865 | 1.240 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2990 | -1.371 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 83</span>| 479.50842 | 1.003 | -1.216 | -0.9258 | -0.9351 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.029 | -0.9984 | -0.2372 | -0.8827 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7937 | -1.065 | -0.5683 | -0.8618 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2141 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.50842 | 91.29 | -5.416 | -0.9037 | -2.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.642 | 0.4066 | 1.095 | 0.05823 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7918 | 0.7302 | 1.537 | 0.9652 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6962 | 2.007 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.50842</span> | 91.29 | 0.004446 | 0.2883 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009643 | 0.6003 | 1.095 | 0.05823 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7918 | 0.7302 | 1.537 | 0.9652 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6962 | 2.007 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.7463 | 1.081 | -0.02105 | -0.05532 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3572 | 0.5118 | -0.07839 | 1.134 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4206 | 0.01709 | -0.5616 | 0.5218 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2429 | -1.361 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 84</span>| 479.50515 | 1.004 | -1.216 | -0.9258 | -0.9351 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.029 | -0.9987 | -0.2372 | -0.8834 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7935 | -1.065 | -0.5680 | -0.8621 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2133 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.50515 | 91.33 | -5.416 | -0.9037 | -2.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.642 | 0.4065 | 1.095 | 0.05821 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7919 | 0.7302 | 1.537 | 0.9649 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6964 | 2.008 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.50515</span> | 91.33 | 0.004443 | 0.2883 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009641 | 0.6002 | 1.095 | 0.05821 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7919 | 0.7302 | 1.537 | 0.9649 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6964 | 2.008 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 85</span>| 479.49887 | 1.004 | -1.219 | -0.9257 | -0.9350 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.030 | -0.9997 | -0.2363 | -0.8851 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7928 | -1.066 | -0.5675 | -0.8630 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2104 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.49887 | 91.39 | -5.419 | -0.9037 | -2.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.642 | 0.4060 | 1.095 | 0.05816 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7925 | 0.7293 | 1.538 | 0.9641 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6963 | 2.011 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.49887</span> | 91.39 | 0.004434 | 0.2883 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009634 | 0.6001 | 1.095 | 0.05816 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7925 | 0.7293 | 1.538 | 0.9641 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6963 | 2.011 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 8.922 | 1.081 | 0.1004 | -0.07252 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3520 | 0.4871 | 0.2543 | 1.578 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3854 | 0.03465 | -0.5794 | 0.4083 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2550 | -1.344 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 86</span>| 479.48147 | 1.003 | -1.221 | -0.9257 | -0.9348 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.031 | -1.001 | -0.2344 | -0.8861 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7921 | -1.067 | -0.5658 | -0.8636 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2068 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.48147 | 91.29 | -5.421 | -0.9036 | -2.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.643 | 0.4054 | 1.096 | 0.05813 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7930 | 0.7283 | 1.540 | 0.9635 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6963 | 2.016 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.48147</span> | 91.29 | 0.004421 | 0.2883 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009626 | 0.6000 | 1.096 | 0.05813 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7930 | 0.7283 | 1.540 | 0.9635 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6963 | 2.016 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 87</span>| 479.46291 | 1.003 | -1.226 | -0.9256 | -0.9345 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.032 | -1.003 | -0.2312 | -0.8874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7910 | -1.069 | -0.5631 | -0.8644 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.2012 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.46291 | 91.29 | -5.426 | -0.9035 | -2.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.645 | 0.4045 | 1.097 | 0.05809 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7937 | 0.7267 | 1.543 | 0.9627 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6964 | 2.022 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.46291</span> | 91.29 | 0.004402 | 0.2883 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009612 | 0.5998 | 1.097 | 0.05809 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7937 | 0.7267 | 1.543 | 0.9627 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6964 | 2.022 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 88</span>| 479.38653 | 1.003 | -1.248 | -0.9250 | -0.9332 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.039 | -1.013 | -0.2154 | -0.8940 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7859 | -1.078 | -0.5497 | -0.8687 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.067 | -0.1734 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.38653 | 91.26 | -5.448 | -0.9030 | -2.196 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.652 | 0.4000 | 1.104 | 0.05790 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7975 | 0.7188 | 1.559 | 0.9587 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6966 | 2.056 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.38653</span> | 91.26 | 0.004306 | 0.2884 | 0.1113 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009547 | 0.5987 | 1.104 | 0.05790 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7975 | 0.7188 | 1.559 | 0.9587 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6966 | 2.056 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 89</span>| 479.33405 | 1.002 | -1.333 | -0.9226 | -0.9281 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.066 | -1.051 | -0.1533 | -0.9198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7659 | -1.112 | -0.4971 | -0.8853 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.066 | -0.06439 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.33405 | 91.15 | -5.533 | -0.9008 | -2.190 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.678 | 0.3823 | 1.129 | 0.05715 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8121 | 0.6876 | 1.621 | 0.9427 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6975 | 2.188 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.33405</span> | 91.15 | 0.003953 | 0.2889 | 0.1119 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009294 | 0.5944 | 1.129 | 0.05715 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8121 | 0.6876 | 1.621 | 0.9427 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6975 | 2.188 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -22.35 | 0.8049 | 0.3265 | -0.06456 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3038 | 0.2091 | 1.763 | 1.473 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5535 | -2.463 | 1.244 | -0.6274 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.702 | -0.2760 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 90</span>| 479.70817 | 1.005 | -1.492 | -0.9504 | -0.9122 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.121 | -1.106 | -0.1774 | -0.9510 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7305 | -1.145 | -0.4385 | -0.8800 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.177 | -0.01012 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.70817 | 91.47 | -5.692 | -0.9256 | -2.175 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.734 | 0.3572 | 1.119 | 0.05625 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8380 | 0.6579 | 1.691 | 0.9478 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6020 | 2.254 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.70817</span> | 91.47 | 0.003371 | 0.2838 | 0.1137 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008794 | 0.5884 | 1.119 | 0.05625 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8380 | 0.6579 | 1.691 | 0.9478 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6020 | 2.254 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 91</span>| 479.27063 | 1.005 | -1.375 | -0.9298 | -0.9240 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.080 | -1.065 | -0.1597 | -0.9281 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7567 | -1.120 | -0.4820 | -0.8839 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.095 | -0.05030 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.27063 | 91.42 | -5.575 | -0.9073 | -2.186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.693 | 0.3758 | 1.127 | 0.05692 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8189 | 0.6801 | 1.639 | 0.9441 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6726 | 2.206 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.27063</span> | 91.42 | 0.003793 | 0.2876 | 0.1123 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009162 | 0.5929 | 1.127 | 0.05692 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8189 | 0.6801 | 1.639 | 0.9441 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6726 | 2.206 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.862 | 0.7516 | 0.3576 | -0.07893 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2806 | -0.4298 | 1.369 | 1.213 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5227 | -2.562 | 2.801 | -1.010 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.234 | -0.5388 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 92</span>| 479.18239 | 1.005 | -1.423 | -0.9401 | -0.9189 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.098 | -1.064 | -0.1729 | -0.9195 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7414 | -1.117 | -0.4967 | -0.8806 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04375 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.18239 | 91.43 | -5.623 | -0.9165 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.710 | 0.3764 | 1.121 | 0.05716 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8300 | 0.6834 | 1.622 | 0.9472 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6830 | 2.213 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.18239</span> | 91.43 | 0.003613 | 0.2857 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009001 | 0.5930 | 1.121 | 0.05716 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8300 | 0.6834 | 1.622 | 0.9472 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6830 | 2.213 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.797 | 0.6564 | -0.1913 | -0.04289 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2359 | -0.3012 | 1.209 | 1.124 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4349 | -2.322 | 2.160 | -0.7215 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1578 | -0.4171 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 93</span>| 479.53483 | 0.9938 | -1.508 | -0.8927 | -0.9141 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.127 | -1.054 | -0.1802 | -0.9016 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7110 | -1.089 | -0.5260 | -0.8567 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.093 | -0.01567 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.53483 | 90.44 | -5.708 | -0.8742 | -2.177 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.740 | 0.3812 | 1.118 | 0.05768 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8523 | 0.7081 | 1.587 | 0.9700 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6741 | 2.248 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.53483</span> | 90.44 | 0.003320 | 0.2944 | 0.1134 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008741 | 0.5942 | 1.118 | 0.05768 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8523 | 0.7081 | 1.587 | 0.9700 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6741 | 2.248 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 94</span>| 479.57437 | 0.9943 | -1.436 | -0.9336 | -0.9181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.102 | -1.062 | -0.1777 | -0.9209 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7362 | -1.106 | -0.5073 | -0.8753 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.084 | -0.03890 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.57437 | 90.49 | -5.636 | -0.9106 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.715 | 0.3775 | 1.119 | 0.05712 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8338 | 0.6933 | 1.609 | 0.9523 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6824 | 2.219 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.57437</span> | 90.49 | 0.003567 | 0.2869 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008961 | 0.5933 | 1.119 | 0.05712 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8338 | 0.6933 | 1.609 | 0.9523 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6824 | 2.219 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 95</span>| 479.18328 | 1.003 | -1.424 | -0.9400 | -0.9189 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.098 | -1.064 | -0.1736 | -0.9201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7412 | -1.115 | -0.4980 | -0.8802 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04351 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.18328 | 91.28 | -5.624 | -0.9164 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.711 | 0.3765 | 1.121 | 0.05715 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8302 | 0.6847 | 1.620 | 0.9476 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6831 | 2.214 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.18328</span> | 91.28 | 0.003612 | 0.2857 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009000 | 0.5930 | 1.121 | 0.05715 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8302 | 0.6847 | 1.620 | 0.9476 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6831 | 2.214 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 96</span>| 479.17990 | 1.004 | -1.423 | -0.9401 | -0.9189 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.098 | -1.064 | -0.1732 | -0.9198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7413 | -1.116 | -0.4973 | -0.8805 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04364 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.1799 | 91.36 | -5.623 | -0.9164 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.710 | 0.3764 | 1.121 | 0.05716 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8301 | 0.6840 | 1.621 | 0.9474 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6831 | 2.214 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.1799</span> | 91.36 | 0.003612 | 0.2857 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009001 | 0.5930 | 1.121 | 0.05716 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8301 | 0.6840 | 1.621 | 0.9474 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6831 | 2.214 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.933 | 0.6514 | -0.2757 | -0.03244 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2382 | -0.2823 | 1.183 | 1.090 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4397 | -2.345 | 2.145 | -0.7620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1240 | -0.3947 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 97</span>| 479.17667 | 1.005 | -1.424 | -0.9399 | -0.9189 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.098 | -1.064 | -0.1735 | -0.9200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7411 | -1.116 | -0.4978 | -0.8802 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04350 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.17667 | 91.44 | -5.624 | -0.9162 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.711 | 0.3765 | 1.121 | 0.05715 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8302 | 0.6845 | 1.621 | 0.9476 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6831 | 2.214 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.17667</span> | 91.44 | 0.003611 | 0.2857 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009000 | 0.5930 | 1.121 | 0.05715 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8302 | 0.6845 | 1.621 | 0.9476 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6831 | 2.214 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.521 | 0.6547 | -0.1751 | -0.04313 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2353 | -0.2995 | 1.118 | 1.121 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4506 | -2.323 | 2.084 | -0.7259 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1653 | -0.4503 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 98</span>| 479.17418 | 1.004 | -1.424 | -0.9398 | -0.9188 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.098 | -1.064 | -0.1738 | -0.9202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7410 | -1.115 | -0.4983 | -0.8800 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04335 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.17418 | 91.36 | -5.624 | -0.9161 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.711 | 0.3765 | 1.121 | 0.05714 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8303 | 0.6850 | 1.620 | 0.9478 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6831 | 2.214 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.17418</span> | 91.36 | 0.003610 | 0.2857 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008999 | 0.5930 | 1.121 | 0.05714 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8303 | 0.6850 | 1.620 | 0.9478 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6831 | 2.214 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.859 | 0.6491 | -0.2708 | -0.03145 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2380 | -0.2786 | 1.113 | 1.074 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4387 | -2.285 | 2.045 | -0.7498 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1354 | -0.4011 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 99</span>| 479.17107 | 1.005 | -1.424 | -0.9396 | -0.9188 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.098 | -1.064 | -0.1740 | -0.9204 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7408 | -1.114 | -0.4988 | -0.8798 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04320 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.17107 | 91.44 | -5.624 | -0.9160 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.711 | 0.3766 | 1.121 | 0.05714 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8305 | 0.6855 | 1.619 | 0.9480 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6831 | 2.214 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.17107</span> | 91.44 | 0.003609 | 0.2858 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008997 | 0.5930 | 1.121 | 0.05714 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8305 | 0.6855 | 1.619 | 0.9480 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6831 | 2.214 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.569 | 0.6522 | -0.1642 | -0.04243 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2349 | -0.2958 | 1.101 | 1.106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4222 | -2.201 | 1.058 | -0.2096 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2358 | -0.4015 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 100</span>| 479.16873 | 1.004 | -1.425 | -0.9393 | -0.9188 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.099 | -1.064 | -0.1743 | -0.9206 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7406 | -1.114 | -0.4991 | -0.8797 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04303 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.16873 | 91.36 | -5.625 | -0.9158 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.711 | 0.3766 | 1.121 | 0.05713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8306 | 0.6860 | 1.619 | 0.9481 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6830 | 2.214 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.16873</span> | 91.36 | 0.003607 | 0.2858 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008996 | 0.5931 | 1.121 | 0.05713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8306 | 0.6860 | 1.619 | 0.9481 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6830 | 2.214 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.833 | 0.6464 | -0.2551 | -0.03020 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2388 | -0.2745 | 1.092 | 1.036 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4378 | -2.238 | 1.100 | -0.2036 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2823 | -0.3907 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 101</span>| 479.16547 | 1.005 | -1.426 | -0.9390 | -0.9187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.099 | -1.063 | -0.1745 | -0.9206 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7403 | -1.113 | -0.4993 | -0.8795 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04283 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.16547 | 91.42 | -5.626 | -0.9155 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.711 | 0.3767 | 1.121 | 0.05713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8308 | 0.6865 | 1.619 | 0.9483 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6830 | 2.215 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.16547</span> | 91.42 | 0.003605 | 0.2859 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008994 | 0.5931 | 1.121 | 0.05713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8308 | 0.6865 | 1.619 | 0.9483 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6830 | 2.215 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.367 | 0.6482 | -0.1602 | -0.03907 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2347 | -0.2874 | 1.147 | 1.057 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4142 | -2.141 | 1.081 | -0.1748 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2414 | -0.4049 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 102</span>| 479.16316 | 1.004 | -1.426 | -0.9389 | -0.9187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.099 | -1.063 | -0.1748 | -0.9208 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7401 | -1.113 | -0.4996 | -0.8794 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04264 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.16316 | 91.36 | -5.626 | -0.9154 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.711 | 0.3768 | 1.120 | 0.05713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8310 | 0.6872 | 1.618 | 0.9484 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6829 | 2.215 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.16316</span> | 91.36 | 0.003603 | 0.2859 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008992 | 0.5931 | 1.120 | 0.05713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8310 | 0.6872 | 1.618 | 0.9484 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6829 | 2.215 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.810 | 0.6431 | -0.2376 | -0.02872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2384 | -0.2689 | 1.073 | 1.021 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4195 | -2.179 | 2.025 | -0.6985 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1403 | -0.3873 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 103</span>| 479.15976 | 1.005 | -1.427 | -0.9385 | -0.9187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.099 | -1.063 | -0.1751 | -0.9208 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7399 | -1.112 | -0.5000 | -0.8792 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04242 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.15976 | 91.41 | -5.627 | -0.9150 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.712 | 0.3768 | 1.120 | 0.05713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8311 | 0.6876 | 1.618 | 0.9486 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6829 | 2.215 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.15976</span> | 91.41 | 0.003601 | 0.2860 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008990 | 0.5931 | 1.120 | 0.05713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8311 | 0.6876 | 1.618 | 0.9486 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6829 | 2.215 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.385 | 0.6444 | -0.1513 | -0.03575 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2363 | -0.2788 | 1.057 | 1.037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4304 | -2.135 | 1.940 | -0.6607 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1552 | -0.4034 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 104</span>| 479.15697 | 1.004 | -1.427 | -0.9385 | -0.9187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.099 | -1.063 | -0.1754 | -0.9212 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7397 | -1.111 | -0.5007 | -0.8790 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04228 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.15697 | 91.37 | -5.627 | -0.9150 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.712 | 0.3769 | 1.120 | 0.05712 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8312 | 0.6883 | 1.617 | 0.9488 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6829 | 2.215 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.15697</span> | 91.37 | 0.003600 | 0.2860 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008990 | 0.5931 | 1.120 | 0.05712 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8312 | 0.6883 | 1.617 | 0.9488 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6829 | 2.215 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.828 | 0.6406 | -0.2090 | -0.02895 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2376 | -0.2659 | 1.059 | 0.9695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4112 | -2.078 | 1.041 | -0.1304 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2608 | -0.3859 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 105</span>| 479.15524 | 1.005 | -1.427 | -0.9384 | -0.9187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.099 | -1.063 | -0.1758 | -0.9215 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7396 | -1.111 | -0.5010 | -0.8789 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04216 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.15524 | 91.45 | -5.627 | -0.9149 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.712 | 0.3769 | 1.120 | 0.05711 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8313 | 0.6888 | 1.617 | 0.9489 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6828 | 2.215 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.15524</span> | 91.45 | 0.003599 | 0.2860 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008989 | 0.5931 | 1.120 | 0.05711 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8313 | 0.6888 | 1.617 | 0.9489 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6828 | 2.215 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.191 | 0.6447 | -0.1017 | -0.04048 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2348 | -0.2858 | 1.095 | 1.009 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3975 | -1.983 | 1.956 | -0.5702 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1591 | -0.3996 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 106</span>| 479.15192 | 1.004 | -1.428 | -0.9381 | -0.9186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.100 | -1.063 | -0.1760 | -0.9214 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7393 | -1.110 | -0.5013 | -0.8787 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04194 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.15192 | 91.38 | -5.628 | -0.9146 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.712 | 0.3770 | 1.120 | 0.05711 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8315 | 0.6892 | 1.616 | 0.9490 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6828 | 2.216 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.15192</span> | 91.38 | 0.003597 | 0.2861 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008987 | 0.5932 | 1.120 | 0.05711 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8315 | 0.6892 | 1.616 | 0.9490 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6828 | 2.216 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.012 | 0.6390 | -0.1711 | -0.03027 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2366 | -0.2653 | 1.098 | 0.9640 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4101 | -2.024 | 0.9749 | -0.1142 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2645 | -0.3871 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 107</span>| 479.14897 | 1.005 | -1.428 | -0.9380 | -0.9186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.100 | -1.063 | -0.1764 | -0.9218 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7392 | -1.110 | -0.5017 | -0.8787 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04178 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.14897 | 91.42 | -5.628 | -0.9146 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.712 | 0.3771 | 1.120 | 0.05710 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8317 | 0.6900 | 1.616 | 0.9491 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6827 | 2.216 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.14897</span> | 91.42 | 0.003596 | 0.2861 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008986 | 0.5932 | 1.120 | 0.05710 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8317 | 0.6900 | 1.616 | 0.9491 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6827 | 2.216 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 108</span>| 479.14773 | 1.005 | -1.428 | -0.9379 | -0.9186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.100 | -1.062 | -0.1770 | -0.9223 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7390 | -1.109 | -0.5022 | -0.8786 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04159 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.14773 | 91.47 | -5.628 | -0.9145 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.712 | 0.3771 | 1.120 | 0.05708 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8318 | 0.6909 | 1.615 | 0.9491 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6826 | 2.216 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.14773</span> | 91.47 | 0.003595 | 0.2861 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008985 | 0.5932 | 1.120 | 0.05708 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8318 | 0.6909 | 1.615 | 0.9491 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6826 | 2.216 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 7.333 | 0.6414 | -0.06030 | -0.04156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2338 | -0.2836 | 1.014 | 1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3897 | -1.922 | 0.8816 | -0.1288 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.1940 | -0.4011 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 109</span>| 479.14119 | 1.004 | -1.430 | -0.9374 | -0.9185 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.100 | -1.062 | -0.1775 | -0.9218 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7383 | -1.108 | -0.5019 | -0.8783 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04112 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.14119 | 91.39 | -5.630 | -0.9140 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.713 | 0.3774 | 1.119 | 0.05710 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8323 | 0.6917 | 1.616 | 0.9495 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6826 | 2.217 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.14119</span> | 91.39 | 0.003588 | 0.2862 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008979 | 0.5933 | 1.119 | 0.05710 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8323 | 0.6917 | 1.616 | 0.9495 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6826 | 2.217 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.4299 | 0.6321 | -0.1435 | -0.02760 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2360 | -0.2479 | 1.019 | 0.9518 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3967 | -1.860 | 1.900 | -0.5922 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1599 | -0.3806 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 110</span>| 479.13501 | 1.005 | -1.431 | -0.9373 | -0.9185 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.101 | -1.062 | -0.1783 | -0.9226 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7379 | -1.106 | -0.5035 | -0.8778 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04080 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.13501 | 91.42 | -5.631 | -0.9139 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.713 | 0.3775 | 1.119 | 0.05707 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8326 | 0.6932 | 1.614 | 0.9500 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6827 | 2.217 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.13501</span> | 91.42 | 0.003586 | 0.2862 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008977 | 0.5933 | 1.119 | 0.05707 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8326 | 0.6932 | 1.614 | 0.9500 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6827 | 2.217 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.960 | 0.6324 | -0.1010 | -0.03176 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2344 | -0.2516 | 0.9454 | 0.8792 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3822 | -1.742 | 0.9146 | -0.04263 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2425 | -0.3771 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 111</span>| 479.13244 | 1.004 | -1.432 | -0.9368 | -0.9184 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.101 | -1.061 | -0.1790 | -0.9224 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7372 | -1.105 | -0.5036 | -0.8775 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.04025 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.13244 | 91.33 | -5.632 | -0.9135 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.714 | 0.3778 | 1.119 | 0.05708 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8331 | 0.6941 | 1.614 | 0.9502 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6825 | 2.218 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.13244</span> | 91.33 | 0.003580 | 0.2863 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008971 | 0.5933 | 1.119 | 0.05708 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8331 | 0.6941 | 1.614 | 0.9502 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6825 | 2.218 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.808 | 0.6219 | -0.1958 | -0.01683 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2369 | -0.2179 | 0.9347 | 0.8364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3987 | -1.797 | 0.8150 | -0.05765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2618 | -0.3704 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 112</span>| 479.12666 | 1.004 | -1.434 | -0.9365 | -0.9183 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.102 | -1.060 | -0.1796 | -0.9220 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7365 | -1.104 | -0.5033 | -0.8772 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.03975 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.12666 | 91.40 | -5.634 | -0.9132 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.714 | 0.3782 | 1.118 | 0.05709 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8336 | 0.6951 | 1.614 | 0.9505 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6824 | 2.218 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.12666</span> | 91.40 | 0.003574 | 0.2863 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008965 | 0.5934 | 1.118 | 0.05709 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8336 | 0.6951 | 1.614 | 0.9505 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6824 | 2.218 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 0.9955 | 0.6218 | -0.09617 | -0.02448 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2342 | -0.2176 | 0.9924 | 0.8560 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3772 | -1.645 | 1.883 | -0.4422 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1320 | -0.3750 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 113</span>| 479.12255 | 1.004 | -1.436 | -0.9361 | -0.9182 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.103 | -1.060 | -0.1805 | -0.9221 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7358 | -1.103 | -0.5043 | -0.8768 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.03920 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.12255 | 91.34 | -5.636 | -0.9129 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.715 | 0.3784 | 1.118 | 0.05709 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8341 | 0.6962 | 1.613 | 0.9509 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6824 | 2.219 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.12255</span> | 91.34 | 0.003569 | 0.2864 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008960 | 0.5935 | 1.118 | 0.05709 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8341 | 0.6962 | 1.613 | 0.9509 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6824 | 2.219 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.522 | 0.6133 | -0.1571 | -0.01492 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2353 | -0.1923 | 0.9045 | 0.7846 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3572 | -1.629 | 0.8508 | 0.03564 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2811 | -0.3561 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 114</span>| 479.11855 | 1.005 | -1.437 | -0.9356 | -0.9182 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.103 | -1.059 | -0.1812 | -0.9217 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7351 | -1.102 | -0.5043 | -0.8766 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.084 | -0.03859 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.11855 | 91.41 | -5.637 | -0.9124 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.716 | 0.3787 | 1.118 | 0.05710 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8346 | 0.6968 | 1.613 | 0.9510 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6823 | 2.220 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.11855</span> | 91.41 | 0.003562 | 0.2865 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008953 | 0.5936 | 1.118 | 0.05710 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8346 | 0.6968 | 1.613 | 0.9510 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6823 | 2.220 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.813 | 0.6131 | -0.03713 | -0.02450 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2319 | -0.1976 | 0.8863 | 0.8390 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3589 | -1.516 | 0.8806 | -0.4426 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1647 | -0.3784 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 115</span>| 479.11487 | 1.004 | -1.439 | -0.9352 | -0.9181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.104 | -1.058 | -0.1819 | -0.9213 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7344 | -1.101 | -0.5040 | -0.8763 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.084 | -0.03810 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.11487 | 91.37 | -5.639 | -0.9121 | -2.180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.716 | 0.3790 | 1.117 | 0.05711 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8352 | 0.6977 | 1.613 | 0.9514 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6823 | 2.220 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.11487</span> | 91.37 | 0.003555 | 0.2866 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008947 | 0.5936 | 1.117 | 0.05711 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8352 | 0.6977 | 1.613 | 0.9514 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6823 | 2.220 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.684 | 0.6054 | -0.08346 | -0.01559 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2328 | -0.1708 | 0.9518 | 0.8099 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3621 | -1.485 | 0.9267 | -0.3776 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1041 | -0.3537 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 116</span>| 479.11139 | 1.005 | -1.441 | -0.9347 | -0.9181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.105 | -1.058 | -0.1829 | -0.9211 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7337 | -1.100 | -0.5039 | -0.8760 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.083 | -0.03771 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.11139 | 91.41 | -5.641 | -0.9117 | -2.180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.717 | 0.3792 | 1.117 | 0.05712 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8357 | 0.6988 | 1.613 | 0.9517 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6824 | 2.221 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.11139</span> | 91.41 | 0.003549 | 0.2867 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008941 | 0.5937 | 1.117 | 0.05712 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8357 | 0.6988 | 1.613 | 0.9517 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6824 | 2.221 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.241 | 0.6036 | 0.0009951 | -0.02154 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2300 | -0.1727 | 0.8524 | 0.8311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3642 | -1.386 | 1.866 | -0.3472 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1024 | -0.3634 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 117</span>| 479.10851 | 1.004 | -1.443 | -0.9342 | -0.9180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.105 | -1.058 | -0.1837 | -0.9207 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7329 | -1.100 | -0.5043 | -0.8759 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.084 | -0.03710 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.10851 | 91.37 | -5.643 | -0.9112 | -2.180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.718 | 0.3794 | 1.117 | 0.05713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8363 | 0.6988 | 1.613 | 0.9517 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6823 | 2.222 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.10851</span> | 91.37 | 0.003542 | 0.2868 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008933 | 0.5937 | 1.117 | 0.05713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8363 | 0.6988 | 1.613 | 0.9517 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6823 | 2.222 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.500 | 0.5956 | -0.03344 | -0.01385 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2306 | -0.1498 | 0.8910 | 0.8240 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3570 | -1.405 | 0.8461 | -0.3572 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.08808 | -0.3487 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 118</span>| 479.10606 | 1.005 | -1.445 | -0.9338 | -0.9180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.106 | -1.057 | -0.1846 | -0.9207 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7320 | -1.099 | -0.5047 | -0.8757 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.084 | -0.03650 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.10606 | 91.43 | -5.645 | -0.9108 | -2.180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.719 | 0.3796 | 1.116 | 0.05713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8369 | 0.6994 | 1.612 | 0.9519 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6822 | 2.222 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.10606</span> | 91.43 | 0.003535 | 0.2868 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008927 | 0.5938 | 1.116 | 0.05713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8369 | 0.6994 | 1.612 | 0.9519 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6822 | 2.222 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.260 | 0.5953 | 0.07226 | -0.02302 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2275 | -0.1573 | 0.8150 | 0.8159 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3410 | -1.340 | 0.8208 | 0.1422 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2750 | -0.3500 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 119</span>| 479.10199 | 1.004 | -1.447 | -0.9337 | -0.9181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.107 | -1.057 | -0.1854 | -0.9204 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7311 | -1.099 | -0.5045 | -0.8757 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.084 | -0.03604 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.10199 | 91.37 | -5.647 | -0.9107 | -2.180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.720 | 0.3799 | 1.116 | 0.05714 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8375 | 0.6999 | 1.613 | 0.9520 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6821 | 2.223 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.10199</span> | 91.37 | 0.003528 | 0.2869 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008919 | 0.5938 | 1.116 | 0.05714 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8375 | 0.6999 | 1.613 | 0.9520 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6821 | 2.223 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.7698 | 0.5858 | -0.004343 | -0.01418 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2278 | -0.1298 | 0.8244 | 0.7686 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3575 | -1.372 | 0.8320 | -0.3359 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2977 | -0.3384 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 120</span>| 479.09844 | 1.005 | -1.448 | -0.9337 | -0.9180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.108 | -1.056 | -0.1863 | -0.9208 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7304 | -1.097 | -0.5051 | -0.8752 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.084 | -0.03534 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.09844 | 91.43 | -5.648 | -0.9108 | -2.180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.720 | 0.3801 | 1.116 | 0.05713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8381 | 0.7011 | 1.612 | 0.9524 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6817 | 2.224 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.09844</span> | 91.43 | 0.003523 | 0.2868 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008914 | 0.5939 | 1.116 | 0.05713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8381 | 0.7011 | 1.612 | 0.9524 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6817 | 2.224 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.894 | 0.5851 | 0.05981 | -0.02077 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2261 | -0.1389 | 0.7622 | 0.7617 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3411 | -1.236 | 0.7863 | 0.1583 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2091 | -0.3951 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 121</span>| 479.09485 | 1.004 | -1.450 | -0.9338 | -0.9180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.108 | -1.056 | -0.1867 | -0.9202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7295 | -1.097 | -0.5051 | -0.8750 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.085 | -0.03445 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.09485 | 91.37 | -5.650 | -0.9108 | -2.180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.721 | 0.3803 | 1.116 | 0.05714 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8388 | 0.7016 | 1.612 | 0.9526 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6813 | 2.225 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.09485</span> | 91.37 | 0.003517 | 0.2868 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008907 | 0.5939 | 1.116 | 0.05714 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8388 | 0.7016 | 1.612 | 0.9526 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6813 | 2.225 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.077 | 0.5762 | -0.02502 | -0.01122 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2275 | -0.1137 | 0.7953 | 0.7347 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3473 | -1.249 | 0.8683 | 0.1895 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2333 | -0.3625 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 122</span>| 479.09211 | 1.005 | -1.452 | -0.9337 | -0.9180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.109 | -1.055 | -0.1878 | -0.9202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7286 | -1.096 | -0.5055 | -0.8752 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.085 | -0.03372 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.09211 | 91.41 | -5.652 | -0.9107 | -2.180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.722 | 0.3805 | 1.115 | 0.05714 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8394 | 0.7021 | 1.612 | 0.9524 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6810 | 2.226 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.09211</span> | 91.41 | 0.003510 | 0.2868 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008900 | 0.5940 | 1.115 | 0.05714 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8394 | 0.7021 | 1.612 | 0.9524 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6810 | 2.226 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.651 | 0.5754 | 0.04071 | -0.01634 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2261 | -0.1150 | 0.8084 | 0.7089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3268 | -1.156 | 0.8610 | 0.1793 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2137 | -0.3471 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 123</span>| 479.08947 | 1.004 | -1.454 | -0.9335 | -0.9181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.110 | -1.055 | -0.1890 | -0.9199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7277 | -1.096 | -0.5056 | -0.8754 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.085 | -0.03307 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.08947 | 91.37 | -5.654 | -0.9105 | -2.180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.722 | 0.3808 | 1.115 | 0.05715 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8401 | 0.7021 | 1.611 | 0.9522 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6809 | 2.226 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.08947</span> | 91.37 | 0.003504 | 0.2869 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008893 | 0.5941 | 1.115 | 0.05715 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8401 | 0.7021 | 1.611 | 0.9522 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6809 | 2.226 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.8529 | 0.5679 | -0.006947 | -0.009666 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2263 | -0.09399 | 0.7582 | 0.6848 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3382 | -1.232 | 0.7736 | -0.3452 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1950 | -0.3796 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 124</span>| 479.08673 | 1.005 | -1.456 | -0.9331 | -0.9181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.111 | -1.054 | -0.1901 | -0.9198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7269 | -1.095 | -0.5060 | -0.8751 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.085 | -0.03242 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.08673 | 91.42 | -5.656 | -0.9102 | -2.180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.723 | 0.3808 | 1.114 | 0.05716 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8406 | 0.7030 | 1.611 | 0.9525 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6810 | 2.227 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.08673</span> | 91.42 | 0.003498 | 0.2870 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008887 | 0.5941 | 1.114 | 0.05716 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8406 | 0.7030 | 1.611 | 0.9525 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6810 | 2.227 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.055 | 0.5667 | 0.07240 | -0.01542 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2241 | -0.1033 | 0.7160 | 0.6904 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3260 | -1.123 | 0.7675 | 0.1856 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.1986 | -0.4973 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 125</span>| 479.08385 | 1.004 | -1.457 | -0.9328 | -0.9181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.112 | -1.054 | -0.1908 | -0.9191 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7261 | -1.095 | -0.5059 | -0.8749 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.085 | -0.03140 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.08385 | 91.37 | -5.657 | -0.9100 | -2.180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.724 | 0.3808 | 1.114 | 0.05718 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8412 | 0.7034 | 1.611 | 0.9527 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6808 | 2.228 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.08385</span> | 91.37 | 0.003491 | 0.2870 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008879 | 0.5941 | 1.114 | 0.05718 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8412 | 0.7034 | 1.611 | 0.9527 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6808 | 2.228 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.7735 | 0.5583 | 0.01997 | -0.008335 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2243 | -0.08958 | 0.6952 | 0.6337 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3199 | -1.102 | 0.8222 | 0.2014 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2310 | -0.4538 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 126</span>| 479.08143 | 1.005 | -1.459 | -0.9328 | -0.9181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.112 | -1.054 | -0.1918 | -0.9191 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7254 | -1.094 | -0.5066 | -0.8749 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.086 | -0.03018 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.08143 | 91.42 | -5.659 | -0.9100 | -2.180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.725 | 0.3810 | 1.113 | 0.05718 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8417 | 0.7042 | 1.610 | 0.9527 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6804 | 2.230 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.08143</span> | 91.42 | 0.003486 | 0.2870 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008874 | 0.5941 | 1.113 | 0.05718 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8417 | 0.7042 | 1.610 | 0.9527 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6804 | 2.230 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.589 | 0.5568 | 0.08446 | -0.01637 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2217 | -0.09943 | 0.6530 | 0.6713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3160 | -1.044 | 0.6971 | -0.3035 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2323 | -0.3746 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 127</span>| 479.07858 | 1.004 | -1.461 | -0.9326 | -0.9181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.113 | -1.054 | -0.1923 | -0.9184 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7246 | -1.093 | -0.5066 | -0.8747 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.086 | -0.02916 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.07858 | 91.36 | -5.661 | -0.9098 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.725 | 0.3811 | 1.113 | 0.05720 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8423 | 0.7045 | 1.610 | 0.9529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6802 | 2.231 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.07858</span> | 91.36 | 0.003479 | 0.2870 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008866 | 0.5941 | 1.113 | 0.05720 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8423 | 0.7045 | 1.610 | 0.9529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6802 | 2.231 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.147 | 0.5485 | 0.01974 | -0.006990 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2231 | -0.08394 | 0.6583 | 0.6424 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3232 | -1.114 | 0.8219 | 0.1886 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.1911 | -0.3375 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 128</span>| 479.07618 | 1.004 | -1.463 | -0.9323 | -0.9182 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.114 | -1.054 | -0.1929 | -0.9181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7237 | -1.093 | -0.5068 | -0.8746 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.086 | -0.02850 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.07618 | 91.40 | -5.663 | -0.9095 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.726 | 0.3811 | 1.113 | 0.05721 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8430 | 0.7050 | 1.610 | 0.9530 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6800 | 2.232 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.07618</span> | 91.40 | 0.003472 | 0.2871 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008858 | 0.5941 | 1.113 | 0.05721 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8430 | 0.7050 | 1.610 | 0.9530 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6800 | 2.232 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.586 | 0.5458 | 0.07904 | -0.01251 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2203 | -0.08960 | 0.6458 | 0.6586 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3031 | -0.9906 | 0.7687 | 0.2646 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.1721 | -0.3284 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 129</span>| 479.07405 | 1.004 | -1.465 | -0.9322 | -0.9183 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.115 | -1.053 | -0.1937 | -0.9179 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7228 | -1.093 | -0.5070 | -0.8747 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.087 | -0.02798 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.07405 | 91.36 | -5.665 | -0.9094 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.727 | 0.3813 | 1.113 | 0.05721 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8437 | 0.7050 | 1.610 | 0.9529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6797 | 2.233 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.07405</span> | 91.36 | 0.003465 | 0.2871 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008850 | 0.5942 | 1.113 | 0.05721 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8437 | 0.7050 | 1.610 | 0.9529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6797 | 2.233 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.296 | 0.5389 | 0.03360 | -0.006173 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2208 | -0.07255 | 0.6853 | 0.5995 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2906 | -1.015 | 0.7685 | 0.2327 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.1765 | -0.3245 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 130</span>| 479.07209 | 1.004 | -1.467 | -0.9321 | -0.9183 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.116 | -1.053 | -0.1949 | -0.9178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7220 | -1.093 | -0.5073 | -0.8750 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.087 | -0.02746 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.07209 | 91.39 | -5.667 | -0.9093 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.728 | 0.3814 | 1.112 | 0.05721 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8442 | 0.7050 | 1.609 | 0.9526 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6796 | 2.233 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.07209</span> | 91.39 | 0.003458 | 0.2871 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008841 | 0.5942 | 1.112 | 0.05721 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8442 | 0.7050 | 1.609 | 0.9526 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6796 | 2.233 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.160 | 0.5372 | 0.08826 | -0.01153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2184 | -0.07756 | 0.6386 | 0.6404 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2977 | -0.9812 | 0.7463 | 0.2047 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.1647 | -0.3238 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 131</span>| 479.07029 | 1.004 | -1.469 | -0.9320 | -0.9184 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.117 | -1.053 | -0.1960 | -0.9175 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7213 | -1.093 | -0.5075 | -0.8752 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.087 | -0.02689 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.07029 | 91.35 | -5.669 | -0.9092 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.729 | 0.3815 | 1.112 | 0.05722 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8447 | 0.7049 | 1.609 | 0.9524 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6795 | 2.234 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.07029</span> | 91.35 | 0.003451 | 0.2872 | 0.1130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008833 | 0.5942 | 1.112 | 0.05722 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8447 | 0.7049 | 1.609 | 0.9524 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6795 | 2.234 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.487 | 0.5301 | 0.04502 | -0.006786 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2180 | -0.06576 | 0.6433 | 0.5523 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2822 | -1.039 | 1.637 | -0.2973 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2152 | -0.3175 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 132</span>| 479.06833 | 1.004 | -1.471 | -0.9316 | -0.9185 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.118 | -1.053 | -0.1965 | -0.9170 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7207 | -1.093 | -0.5082 | -0.8751 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.087 | -0.02616 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.06833 | 91.38 | -5.671 | -0.9088 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.730 | 0.3814 | 1.111 | 0.05724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8452 | 0.7048 | 1.608 | 0.9525 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6792 | 2.235 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.06833</span> | 91.38 | 0.003444 | 0.2872 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008825 | 0.5942 | 1.111 | 0.05724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8452 | 0.7048 | 1.608 | 0.9525 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6792 | 2.235 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 0.6466 | 0.5255 | 0.09166 | -0.01288 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2142 | -0.07904 | 0.5622 | 0.5865 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2779 | -1.008 | 0.7011 | 0.1998 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.1404 | -0.3181 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 133</span>| 479.06868 | 1.003 | -1.472 | -0.9317 | -0.9185 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.118 | -1.053 | -0.1973 | -0.9180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7202 | -1.092 | -0.5093 | -0.8754 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.087 | -0.02567 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.06868 | 91.29 | -5.672 | -0.9090 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.731 | 0.3814 | 1.111 | 0.05721 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8455 | 0.7062 | 1.607 | 0.9522 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6790 | 2.235 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.06868</span> | 91.29 | 0.003441 | 0.2872 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008822 | 0.5942 | 1.111 | 0.05721 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8455 | 0.7062 | 1.607 | 0.9522 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6790 | 2.235 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 134</span>| 479.06735 | 1.004 | -1.472 | -0.9316 | -0.9185 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.118 | -1.053 | -0.1969 | -0.9175 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7205 | -1.092 | -0.5087 | -0.8753 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.087 | -0.02593 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.06735 | 91.33 | -5.672 | -0.9089 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.730 | 0.3814 | 1.111 | 0.05722 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8453 | 0.7054 | 1.608 | 0.9523 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6791 | 2.235 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.06735</span> | 91.33 | 0.003443 | 0.2872 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008823 | 0.5942 | 1.111 | 0.05722 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8453 | 0.7054 | 1.608 | 0.9523 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6791 | 2.235 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.476 | 0.5223 | 0.03269 | -0.003763 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2173 | -0.06616 | 0.5281 | 0.5229 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3041 | -1.023 | 1.607 | -0.2773 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2325 | -0.3192 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 135</span>| 479.06543 | 1.004 | -1.472 | -0.9319 | -0.9185 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.118 | -1.053 | -0.1968 | -0.9175 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7201 | -1.092 | -0.5088 | -0.8751 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.088 | -0.02567 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.06543 | 91.36 | -5.672 | -0.9091 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.731 | 0.3815 | 1.111 | 0.05722 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8456 | 0.7056 | 1.608 | 0.9525 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6790 | 2.235 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.06543</span> | 91.36 | 0.003439 | 0.2872 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008820 | 0.5942 | 1.111 | 0.05722 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8456 | 0.7056 | 1.608 | 0.9525 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6790 | 2.235 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 136</span>| 479.06390 | 1.004 | -1.474 | -0.9324 | -0.9185 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.119 | -1.053 | -0.1965 | -0.9174 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7194 | -1.092 | -0.5089 | -0.8750 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.088 | -0.02528 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.0639 | 91.36 | -5.674 | -0.9095 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.732 | 0.3816 | 1.111 | 0.05723 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8461 | 0.7059 | 1.607 | 0.9526 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6786 | 2.236 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.0639</span> | 91.36 | 0.003434 | 0.2871 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008813 | 0.5943 | 1.111 | 0.05723 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8461 | 0.7059 | 1.607 | 0.9526 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6786 | 2.236 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 137</span>| 479.05708 | 1.004 | -1.481 | -0.9346 | -0.9186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.123 | -1.051 | -0.1952 | -0.9171 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7164 | -1.090 | -0.5089 | -0.8741 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.090 | -0.02338 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.05708 | 91.37 | -5.681 | -0.9115 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.735 | 0.3824 | 1.112 | 0.05724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8483 | 0.7072 | 1.607 | 0.9535 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6769 | 2.238 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.05708</span> | 91.37 | 0.003409 | 0.2867 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008783 | 0.5944 | 1.112 | 0.05724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8483 | 0.7072 | 1.607 | 0.9535 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6769 | 2.238 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 138</span>| 479.03987 | 1.004 | -1.510 | -0.9434 | -0.9188 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.136 | -1.045 | -0.1899 | -0.9157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7043 | -1.085 | -0.5092 | -0.8705 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.098 | -0.01577 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.03987 | 91.37 | -5.710 | -0.9193 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.749 | 0.3852 | 1.114 | 0.05728 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8571 | 0.7123 | 1.607 | 0.9569 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6702 | 2.247 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.03987</span> | 91.37 | 0.003311 | 0.2851 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008662 | 0.5951 | 1.114 | 0.05728 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8571 | 0.7123 | 1.607 | 0.9569 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6702 | 2.247 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.3651 | 0.4285 | -0.5283 | -0.001988 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1991 | 0.06799 | 0.8278 | 0.7155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2362 | -0.3851 | 0.6274 | 0.1204 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.9270 | -0.3308 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 139</span>| 479.01407 | 1.005 | -1.553 | -0.9371 | -0.9187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.158 | -1.041 | -0.1978 | -0.9162 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6881 | -1.086 | -0.5088 | -0.8721 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.097 | -0.01436 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.01407 | 91.44 | -5.753 | -0.9138 | -2.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.770 | 0.3869 | 1.111 | 0.05726 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8690 | 0.7117 | 1.608 | 0.9554 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6704 | 2.249 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.01407</span> | 91.44 | 0.003172 | 0.2862 | 0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008479 | 0.5955 | 1.111 | 0.05726 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8690 | 0.7117 | 1.608 | 0.9554 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6704 | 2.249 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 7.322 | 0.3385 | -0.09736 | -0.005783 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1607 | 0.1322 | 0.5556 | 0.5176 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1562 | -0.2690 | 1.549 | -0.03161 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8578 | -0.3240 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 140</span>| 478.99946 | 1.003 | -1.595 | -0.9294 | -0.9194 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.179 | -1.045 | -0.1992 | -0.9136 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6715 | -1.093 | -0.5132 | -0.8724 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.100 | -0.009543 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.99946 | 91.31 | -5.795 | -0.9069 | -2.182 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.791 | 0.3851 | 1.110 | 0.05734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8811 | 0.7049 | 1.602 | 0.9551 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6678 | 2.255 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.99946</span> | 91.31 | 0.003042 | 0.2876 | 0.1128 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008303 | 0.5951 | 1.110 | 0.05734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8811 | 0.7049 | 1.602 | 0.9551 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6678 | 2.255 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.440 | 0.2525 | 0.1677 | 0.001517 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1272 | 0.05864 | 0.6253 | 0.4352 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1457 | -0.7321 | 1.353 | 0.0009973 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.018 | -0.3498 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 141</span>| 479.00064 | 1.004 | -1.626 | -0.9429 | -0.9240 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.201 | -1.064 | -0.2165 | -0.9169 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6612 | -1.100 | -0.5189 | -0.8809 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.100 | -0.001744 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.00064 | 91.38 | -5.826 | -0.9189 | -2.186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.814 | 0.3763 | 1.103 | 0.05724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8887 | 0.6986 | 1.596 | 0.9470 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6683 | 2.264 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.00064</span> | 91.38 | 0.002950 | 0.2852 | 0.1123 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008117 | 0.5930 | 1.103 | 0.05724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8887 | 0.6986 | 1.596 | 0.9470 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6683 | 2.264 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 142</span>| 478.99385 | 1.004 | -1.610 | -0.9359 | -0.9216 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.190 | -1.054 | -0.2077 | -0.9152 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6665 | -1.096 | -0.5161 | -0.8765 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.100 | -0.005738 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.99385 | 91.39 | -5.810 | -0.9127 | -2.184 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.802 | 0.3808 | 1.107 | 0.05729 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8848 | 0.7019 | 1.599 | 0.9512 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6681 | 2.260 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.99385</span> | 91.39 | 0.002997 | 0.2864 | 0.1126 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008212 | 0.5941 | 1.107 | 0.05729 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8848 | 0.7019 | 1.599 | 0.9512 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6681 | 2.260 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.499 | 0.2382 | -0.03703 | -0.03958 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.09629 | -0.2111 | 0.3210 | 0.2393 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1233 | -0.7892 | 1.126 | -0.4047 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.051 | -0.3984 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 143</span>| 478.98455 | 1.004 | -1.625 | -0.9347 | -0.9200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.200 | -1.054 | -0.2131 | -0.9088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6653 | -1.094 | -0.5167 | -0.8757 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.099 | 0.008183 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.98455 | 91.36 | -5.825 | -0.9116 | -2.182 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.813 | 0.3812 | 1.105 | 0.05748 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8857 | 0.7042 | 1.598 | 0.9520 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6689 | 2.277 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.98455</span> | 91.36 | 0.002951 | 0.2867 | 0.1128 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008125 | 0.5942 | 1.105 | 0.05748 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8857 | 0.7042 | 1.598 | 0.9520 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6689 | 2.277 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.2799 | 0.1926 | -0.02074 | -0.02333 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08052 | -0.1468 | 0.2817 | 0.3348 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1470 | -0.6425 | 1.062 | -0.3208 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8181 | -0.3186 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 144</span>| 478.97736 | 1.005 | -1.639 | -0.9325 | -0.9174 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.210 | -1.043 | -0.2100 | -0.9166 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6557 | -1.093 | -0.5206 | -0.8754 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.097 | 0.01446 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.97736 | 91.42 | -5.839 | -0.9097 | -2.180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.822 | 0.3861 | 1.106 | 0.05725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8927 | 0.7053 | 1.594 | 0.9522 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6711 | 2.284 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.97736</span> | 91.42 | 0.002912 | 0.2871 | 0.1131 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008047 | 0.5953 | 1.106 | 0.05725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8927 | 0.7053 | 1.594 | 0.9522 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6711 | 2.284 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.719 | 0.1644 | 0.1764 | 0.0002018 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06754 | 0.1935 | -0.08189 | -0.1310 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.08678 | -2.826 | 0.8338 | -0.2552 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4561 | -0.1956 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 145</span>| 478.97194 | 1.004 | -1.652 | -0.9304 | -0.9153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.221 | -1.039 | -0.2044 | -0.9254 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6443 | -1.087 | -0.5238 | -0.8740 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.092 | 0.01749 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.97194 | 91.40 | -5.852 | -0.9078 | -2.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.833 | 0.3880 | 1.108 | 0.05699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9010 | 0.7106 | 1.590 | 0.9536 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.97194</span> | 91.40 | 0.002874 | 0.2875 | 0.1133 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.007961 | 0.5958 | 1.108 | 0.05699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9010 | 0.7106 | 1.590 | 0.9536 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.925 | 0.1117 | 0.2312 | 0.02461 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.04286 | 0.3818 | 0.1548 | -0.1592 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.04325 | -0.1382 | 0.7430 | -0.2262 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.01070 | -0.1316 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 146</span>| 479.08778 | 0.9990 | -1.662 | -0.9298 | -0.9158 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.224 | -1.050 | -0.2095 | -0.9175 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6325 | -1.087 | -0.5258 | -0.8715 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.094 | 0.02816 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.08778 | 90.91 | -5.862 | -0.9073 | -2.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.836 | 0.3828 | 1.106 | 0.05722 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9096 | 0.7103 | 1.587 | 0.9559 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6733 | 2.301 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.08778</span> | 90.91 | 0.002845 | 0.2876 | 0.1132 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.007936 | 0.5946 | 1.106 | 0.05722 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9096 | 0.7103 | 1.587 | 0.9559 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6733 | 2.301 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 147</span>| 478.99303 | 1.002 | -1.652 | -0.9306 | -0.9153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.221 | -1.039 | -0.2045 | -0.9253 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6442 | -1.087 | -0.5244 | -0.8738 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.092 | 0.01760 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.99303 | 91.18 | -5.852 | -0.9080 | -2.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.833 | 0.3879 | 1.108 | 0.05700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9011 | 0.7107 | 1.589 | 0.9537 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.99303</span> | 91.18 | 0.002874 | 0.2874 | 0.1133 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.007961 | 0.5958 | 1.108 | 0.05700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9011 | 0.7107 | 1.589 | 0.9537 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 148</span>| 478.97158 | 1.004 | -1.652 | -0.9304 | -0.9153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.221 | -1.039 | -0.2044 | -0.9254 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6443 | -1.087 | -0.5239 | -0.8740 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.092 | 0.01751 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.97158 | 91.37 | -5.852 | -0.9078 | -2.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.833 | 0.3880 | 1.108 | 0.05699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9010 | 0.7106 | 1.590 | 0.9536 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.97158</span> | 91.37 | 0.002874 | 0.2874 | 0.1133 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.007961 | 0.5958 | 1.108 | 0.05699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9010 | 0.7106 | 1.590 | 0.9536 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.1518 | 0.1094 | 0.1916 | 0.02921 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.04385 | 0.3896 | -0.2077 | -0.4379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.03471 | -2.421 | 0.7262 | -0.1589 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.01110 | -0.1305 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 149</span>| 478.97152 | 1.004 | -1.652 | -0.9304 | -0.9153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.221 | -1.039 | -0.2044 | -0.9254 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6443 | -1.086 | -0.5240 | -0.8739 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.092 | 0.01753 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.97152 | 91.37 | -5.852 | -0.9078 | -2.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.833 | 0.3880 | 1.108 | 0.05699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9010 | 0.7109 | 1.590 | 0.9536 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.97152</span> | 91.37 | 0.002874 | 0.2874 | 0.1133 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.007961 | 0.5958 | 1.108 | 0.05699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9010 | 0.7109 | 1.590 | 0.9536 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -0.2246 | 0.1050 | 0.1574 | 0.02036 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.04103 | 0.3470 | -0.3387 | -0.1919 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1172 | -0.1870 | 0.6243 | -0.2341 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.06769 | -0.1265 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 150</span>| 478.97142 | 1.004 | -1.652 | -0.9305 | -0.9153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.221 | -1.039 | -0.2042 | -0.9253 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6442 | -1.086 | -0.5242 | -0.8739 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.092 | 0.01757 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.97142 | 91.38 | -5.852 | -0.9079 | -2.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.833 | 0.3879 | 1.108 | 0.05700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9011 | 0.7110 | 1.589 | 0.9537 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.97142</span> | 91.38 | 0.002874 | 0.2874 | 0.1133 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.007961 | 0.5958 | 1.108 | 0.05700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9011 | 0.7110 | 1.589 | 0.9537 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 0.5593 | 0.1052 | 0.1640 | 0.01900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.04052 | 0.3419 | -0.3227 | -0.1646 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1158 | -0.1768 | 0.1839 | -0.2151 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.04116 | -0.1006 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 151</span>| 478.97143 | 1.004 | -1.652 | -0.9306 | -0.9153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.221 | -1.039 | -0.2041 | -0.9252 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6442 | -1.086 | -0.5243 | -0.8738 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.092 | 0.01761 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.97143 | 91.36 | -5.852 | -0.9079 | -2.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.833 | 0.3879 | 1.108 | 0.05700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9011 | 0.7110 | 1.589 | 0.9538 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.97143</span> | 91.36 | 0.002874 | 0.2874 | 0.1133 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.007961 | 0.5958 | 1.108 | 0.05700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9011 | 0.7110 | 1.589 | 0.9538 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 152</span>| 478.97137 | 1.004 | -1.652 | -0.9305 | -0.9153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.221 | -1.039 | -0.2042 | -0.9253 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6442 | -1.086 | -0.5242 | -0.8738 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.092 | 0.01759 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.97137 | 91.37 | -5.852 | -0.9079 | -2.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.833 | 0.3879 | 1.108 | 0.05700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9011 | 0.7110 | 1.589 | 0.9537 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.97137</span> | 91.37 | 0.002874 | 0.2874 | 0.1133 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.007961 | 0.5958 | 1.108 | 0.05700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9011 | 0.7110 | 1.589 | 0.9537 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -0.4660 | 0.1043 | 0.1497 | 0.02048 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.04080 | 0.3434 | -0.3050 | -0.1804 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2015 | -1.954 | 0.1460 | -0.2263 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.03239 | -0.1147 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 153</span>| 478.97135 | 1.004 | -1.652 | -0.9305 | -0.9153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.221 | -1.039 | -0.2041 | -0.9253 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6441 | -1.086 | -0.5242 | -0.8738 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.092 | 0.01760 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.97135 | 91.36 | -5.852 | -0.9079 | -2.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.833 | 0.3879 | 1.108 | 0.05700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9012 | 0.7110 | 1.589 | 0.9538 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.97135</span> | 91.36 | 0.002874 | 0.2874 | 0.1133 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.007961 | 0.5958 | 1.108 | 0.05700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9012 | 0.7110 | 1.589 | 0.9538 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -0.8144 | 0.1038 | 0.1446 | 0.02101 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.04083 | 0.3431 | -0.3133 | -0.1844 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.05440 | -1.096 | 0.1463 | -0.2004 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.2780 | -0.1269 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 154</span>| 478.97125 | 1.004 | -1.652 | -0.9305 | -0.9153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.221 | -1.039 | -0.2041 | -0.9252 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6441 | -1.086 | -0.5243 | -0.8738 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.092 | 0.01762 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.97125 | 91.37 | -5.852 | -0.9079 | -2.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.833 | 0.3879 | 1.108 | 0.05700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9012 | 0.7111 | 1.589 | 0.9538 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.97125</span> | 91.37 | 0.002874 | 0.2874 | 0.1133 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.007961 | 0.5958 | 1.108 | 0.05700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9012 | 0.7111 | 1.589 | 0.9538 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 0.03985 | 0.1039 | 0.1540 | 0.01970 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.04056 | 0.3392 | -0.3415 | -0.1666 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1386 | -0.1574 | 0.08901 | -0.2003 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.04000 | -0.1187 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 155</span>| 478.97118 | 1.004 | -1.652 | -0.9306 | -0.9153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.221 | -1.039 | -0.2040 | -0.9252 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6440 | -1.086 | -0.5243 | -0.8737 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.092 | 0.01765 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.97118 | 91.37 | -5.852 | -0.9080 | -2.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.833 | 0.3878 | 1.108 | 0.05700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9012 | 0.7112 | 1.589 | 0.9538 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.97118</span> | 91.37 | 0.002874 | 0.2874 | 0.1133 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.007961 | 0.5958 | 1.108 | 0.05700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9012 | 0.7112 | 1.589 | 0.9538 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -0.05720 | 0.1036 | 0.1507 | 0.01972 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.04048 | 0.3375 | -0.2940 | -0.1684 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1979 | -1.920 | 0.1339 | -0.2027 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.04399 | -0.1216 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 156</span>| 478.97118 | 1.004 | -1.652 | -0.9306 | -0.9153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.221 | -1.039 | -0.2040 | -0.9252 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6440 | -1.086 | -0.5243 | -0.8737 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.092 | 0.01765 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.97118 | 91.37 | -5.852 | -0.9080 | -2.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.833 | 0.3878 | 1.108 | 0.05700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9012 | 0.7112 | 1.589 | 0.9538 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.97118</span> | 91.37 | 0.002874 | 0.2874 | 0.1133 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.007961 | 0.5958 | 1.108 | 0.05700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9012 | 0.7112 | 1.589 | 0.9538 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.6749 | 2.288 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>initial ETAs were nudged; (can control by foceiControl(etaNudge=., etaNudge2=))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>ETAs were reset to zero during optimization; (Can control by foceiControl(resetEtaP=.))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>last objective function was not at minimum, possible problems in optimization</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>using R matrix to calculate covariance, can check sandwich or S matrix with $covRS and $covS</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>gradient problems with initial estimate and covariance; see $scaleInfo</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Two-component error by variable is possible with both estimation methods</span></span> +<span class="r-in"><span class="co"># Variance by variable is supported by 'saem' and 'focei'</span></span> +<span class="r-in"><span class="va">f_nlmixr_fomc_sfo_saem_obs_tc</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_tc</span><span class="op">[</span><span class="st">"FOMC-SFO"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"saem"</span>,</span> +<span class="r-in"> error_model <span class="op">=</span> <span class="st">"obs_tc"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> 1: 92.0624 -5.2854 0.1952 1.9494 -1.9431 2.8500 1.6150 0.7315 0.7220 0.4370 6.8425 0.4265 7.3797 0.5659</span> +<span class="r-out co"><span class="r-pr">#></span> 2: 92.7371 -5.3819 0.0345 2.0839 -2.0310 2.7075 1.5342 0.6949 0.8358 0.4151 7.2043 0.0003 8.1096 0.0003</span> +<span class="r-out co"><span class="r-pr">#></span> 3: 9.2941e+01 -5.7880e+00 1.0336e-01 2.5772e+00 -1.5152e+00 2.5721e+00 1.4575e+00 6.6018e-01 7.9403e-01 3.9439e-01 4.5749e+00 1.5986e-05 5.1354e+00 2.8796e-05</span> +<span class="r-out co"><span class="r-pr">#></span> 4: 92.6277 -5.8599 0.0858 2.5068 -1.3253 2.4435 1.3847 0.6272 0.7543 0.3747 3.4165 0.0001 3.9071 0.0016</span> +<span class="r-out co"><span class="r-pr">#></span> 5: 93.0289 -6.0258 0.0528 2.4932 -1.1961 2.3213 1.3154 0.5958 0.7166 0.3559 3.2552 0.0069 3.3744 0.0170</span> +<span class="r-out co"><span class="r-pr">#></span> 6: 93.2107 -6.2881 0.0143 2.4052 -1.1930 2.2053 2.2853 0.5660 0.6808 0.3381 2.8020 0.0086 3.1436 0.0256</span> +<span class="r-out co"><span class="r-pr">#></span> 7: 93.0563 -6.3624 -0.0104 2.3989 -1.1521 2.0950 2.4414 0.5377 0.6467 0.3212 2.6528 0.0209 2.8462 0.0289</span> +<span class="r-out co"><span class="r-pr">#></span> 8: 93.0567 -6.2699 -0.0303 2.3700 -1.0941 1.9903 2.5004 0.5204 0.6144 0.3052 2.3448 0.0314 2.5026 0.0349</span> +<span class="r-out co"><span class="r-pr">#></span> 9: 92.8366 -6.2013 -0.0507 2.3798 -1.0963 1.8907 2.6552 0.4943 0.5837 0.2899 2.2219 0.0368 2.2604 0.0448</span> +<span class="r-out co"><span class="r-pr">#></span> 10: 92.9069 -6.2499 -0.1116 2.3100 -1.0557 1.9625 3.9231 0.4696 0.5545 0.2754 2.0980 0.0359 2.1413 0.0325</span> +<span class="r-out co"><span class="r-pr">#></span> 11: 92.9942 -6.2134 -0.1037 2.3109 -1.0441 1.8643 3.7270 0.4755 0.5268 0.2616 1.9711 0.0372 1.9901 0.0355</span> +<span class="r-out co"><span class="r-pr">#></span> 12: 92.9262 -6.2511 -0.1133 2.2707 -1.0465 1.8430 4.3304 0.4697 0.5004 0.2486 1.8083 0.0346 1.9184 0.0356</span> +<span class="r-out co"><span class="r-pr">#></span> 13: 93.0761 -6.3559 -0.1106 2.2534 -1.0162 2.4826 5.2857 0.4685 0.4754 0.2361 1.7896 0.0331 1.9865 0.0342</span> +<span class="r-out co"><span class="r-pr">#></span> 14: 93.0929 -6.1852 -0.1058 2.2972 -1.0175 2.9964 5.0214 0.4451 0.4516 0.2243 1.8316 0.0309 1.9112 0.0348</span> +<span class="r-out co"><span class="r-pr">#></span> 15: 93.3343 -6.3408 -0.1025 2.2905 -0.9962 3.1132 4.9630 0.4594 0.4291 0.2131 1.8198 0.0338 1.9154 0.0372</span> +<span class="r-out co"><span class="r-pr">#></span> 16: 92.9959 -6.2227 -0.1016 2.2869 -1.0103 3.3338 4.7149 0.4598 0.4076 0.2025 1.8726 0.0327 1.9617 0.0361</span> +<span class="r-out co"><span class="r-pr">#></span> 17: 93.0394 -6.2586 -0.1027 2.2932 -0.9991 3.1671 4.8730 0.4591 0.3872 0.1923 1.8405 0.0336 2.0192 0.0242</span> +<span class="r-out co"><span class="r-pr">#></span> 18: 93.2374 -6.3410 -0.1110 2.2965 -0.9689 3.0087 5.4325 0.4632 0.3679 0.1827 1.9051 0.0351 1.9247 0.0277</span> +<span class="r-out co"><span class="r-pr">#></span> 19: 93.0557 -6.4503 -0.1011 2.2941 -0.9884 2.8583 6.2872 0.4742 0.3495 0.1736 1.8054 0.0345 1.9173 0.0260</span> +<span class="r-out co"><span class="r-pr">#></span> 20: 92.9280 -6.4945 -0.1018 2.2902 -0.9864 3.5934 6.8737 0.4751 0.3320 0.1649 1.7097 0.0372 1.9483 0.0225</span> +<span class="r-out co"><span class="r-pr">#></span> 21: 93.2023 -6.3418 -0.1033 2.2846 -0.9863 3.4138 6.5300 0.4710 0.3154 0.1567 1.7507 0.0318 1.9030 0.0249</span> +<span class="r-out co"><span class="r-pr">#></span> 22: 93.5494 -6.1985 -0.1078 2.2991 -1.0171 3.2431 6.2035 0.4475 0.2996 0.1488 1.7370 0.0342 1.8124 0.0282</span> +<span class="r-out co"><span class="r-pr">#></span> 23: 93.3588 -6.2577 -0.1084 2.2654 -0.9956 3.0809 5.8933 0.4393 0.2869 0.1481 1.6928 0.0380 1.8288 0.0254</span> +<span class="r-out co"><span class="r-pr">#></span> 24: 93.5705 -6.4876 -0.1083 2.2606 -1.0062 3.7095 6.7801 0.4459 0.2726 0.1684 1.7001 0.0377 1.9012 0.0249</span> +<span class="r-out co"><span class="r-pr">#></span> 25: 93.9726 -6.5638 -0.1239 2.2374 -1.0071 5.1357 6.6571 0.4608 0.2755 0.1600 1.6615 0.0382 1.8846 0.0213</span> +<span class="r-out co"><span class="r-pr">#></span> 26: 93.8894 -6.5073 -0.1120 2.2645 -1.0327 4.8789 6.3243 0.4473 0.3014 0.1520 1.7152 0.0340 1.8990 0.0254</span> +<span class="r-out co"><span class="r-pr">#></span> 27: 94.5348 -6.3868 -0.0891 2.3139 -1.0361 5.3856 6.0081 0.4250 0.3080 0.1453 1.7028 0.0385 1.7853 0.0304</span> +<span class="r-out co"><span class="r-pr">#></span> 28: 93.9221 -6.1747 -0.1039 2.3013 -1.0087 5.1163 5.7077 0.4214 0.3136 0.1634 1.6823 0.0340 1.7487 0.0353</span> +<span class="r-out co"><span class="r-pr">#></span> 29: 93.4946 -6.0264 -0.0940 2.3124 -1.0166 5.3744 5.4223 0.4404 0.3114 0.1813 1.6310 0.0370 1.7646 0.0367</span> +<span class="r-out co"><span class="r-pr">#></span> 30: 93.9287 -5.9114 -0.0967 2.3078 -1.0090 5.2017 5.1512 0.4381 0.3048 0.2091 1.5825 0.0393 1.7431 0.0312</span> +<span class="r-out co"><span class="r-pr">#></span> 31: 93.7065 -6.0174 -0.0928 2.2917 -0.9880 5.1935 4.8936 0.4352 0.3109 0.1986 1.5876 0.0392 1.8465 0.0280</span> +<span class="r-out co"><span class="r-pr">#></span> 32: 93.7675 -5.6444 -0.0918 2.3145 -0.9664 4.9338 4.6489 0.4332 0.3090 0.1918 1.6874 0.0332 1.7501 0.0331</span> +<span class="r-out co"><span class="r-pr">#></span> 33: 94.2589 -5.7637 -0.0865 2.3130 -0.9733 4.6871 4.4165 0.4235 0.2935 0.1865 1.7173 0.0355 1.7365 0.0334</span> +<span class="r-out co"><span class="r-pr">#></span> 34: 94.0788 -5.7432 -0.1022 2.3049 -0.9681 4.4528 4.1957 0.4319 0.2962 0.1772 1.6357 0.0361 1.4755 0.0574</span> +<span class="r-out co"><span class="r-pr">#></span> 35: 94.0798 -5.8549 -0.0929 2.2856 -0.9849 4.2301 3.9859 0.4391 0.2937 0.1734 1.6460 0.0275 1.7739 0.0379</span> +<span class="r-out co"><span class="r-pr">#></span> 36: 93.9997 -5.8708 -0.0890 2.2870 -1.0134 4.0186 3.7866 0.4268 0.2819 0.1840 1.5830 0.0258 1.8922 0.0320</span> +<span class="r-out co"><span class="r-pr">#></span> 37: 93.8186 -5.8979 -0.0973 2.2807 -1.0197 3.8177 3.5973 0.4280 0.2778 0.1799 1.5783 0.0282 1.7697 0.0404</span> +<span class="r-out co"><span class="r-pr">#></span> 38: 94.0728 -5.9601 -0.0936 2.3011 -1.0381 3.6268 3.4174 0.4186 0.2944 0.1864 1.5780 0.0294 1.5210 0.0558</span> +<span class="r-out co"><span class="r-pr">#></span> 39: 94.0504 -5.8302 -0.0995 2.2847 -1.0418 3.4455 3.2465 0.4240 0.2796 0.1771 1.6888 0.0242 1.7744 0.0366</span> +<span class="r-out co"><span class="r-pr">#></span> 40: 93.8918 -5.9418 -0.0988 2.2925 -1.0613 3.2732 3.0842 0.4144 0.2672 0.1837 1.7275 0.0232 1.7840 0.0357</span> +<span class="r-out co"><span class="r-pr">#></span> 41: 93.7961 -6.0741 -0.0896 2.2932 -1.0359 3.1095 3.2890 0.4236 0.2606 0.1782 1.7591 0.0212 1.8920 0.0273</span> +<span class="r-out co"><span class="r-pr">#></span> 42: 93.9458 -6.0319 -0.0909 2.3114 -1.0281 3.0544 3.1246 0.4196 0.2598 0.1839 1.6854 0.0310 1.7586 0.0308</span> +<span class="r-out co"><span class="r-pr">#></span> 43: 93.7623 -6.0165 -0.1056 2.2837 -1.0378 3.9092 3.2100 0.4298 0.2468 0.1747 1.7064 0.0286 1.6676 0.0397</span> +<span class="r-out co"><span class="r-pr">#></span> 44: 93.4300 -5.9019 -0.1114 2.2716 -1.0167 4.4100 3.0495 0.4476 0.2345 0.1687 1.7989 0.0253 1.7741 0.0299</span> +<span class="r-out co"><span class="r-pr">#></span> 45: 93.3475 -5.9962 -0.1231 2.2546 -1.0007 6.4879 3.3965 0.4528 0.2452 0.1602 1.7283 0.0276 1.7219 0.0379</span> +<span class="r-out co"><span class="r-pr">#></span> 46: 93.3100 -6.0073 -0.1255 2.2483 -0.9962 6.6009 3.5942 0.4520 0.2533 0.1568 1.6991 0.0258 1.1783 0.0706</span> +<span class="r-out co"><span class="r-pr">#></span> 47: 93.4422 -5.8442 -0.1286 2.2578 -0.9819 6.2709 3.4145 0.4492 0.2637 0.1694 1.6754 0.0317 1.3442 0.0599</span> +<span class="r-out co"><span class="r-pr">#></span> 48: 93.0996 -5.5881 -0.1307 2.2541 -0.9882 5.9573 3.2438 0.4480 0.2665 0.1695 1.7040 0.0285 1.6825 0.0426</span> +<span class="r-out co"><span class="r-pr">#></span> 49: 93.3649 -5.8011 -0.1260 2.2595 -0.9704 5.7230 3.0816 0.4399 0.2646 0.1715 1.6544 0.0297 1.6414 0.0418</span> +<span class="r-out co"><span class="r-pr">#></span> 50: 93.9331 -5.8731 -0.1195 2.2615 -0.9837 5.4368 2.9275 0.4453 0.2735 0.1940 1.6316 0.0289 1.6885 0.0392</span> +<span class="r-out co"><span class="r-pr">#></span> 51: 93.6092 -5.8721 -0.1237 2.2599 -1.0015 5.1650 2.7811 0.4413 0.2865 0.1939 1.6492 0.0272 1.7686 0.0358</span> +<span class="r-out co"><span class="r-pr">#></span> 52: 93.3008 -5.9775 -0.1277 2.2628 -0.9962 4.9067 3.1139 0.4438 0.2946 0.1963 1.5642 0.0337 1.7391 0.0335</span> +<span class="r-out co"><span class="r-pr">#></span> 53: 93.6347 -6.0805 -0.1189 2.2663 -1.0177 4.6614 3.5169 0.4335 0.2962 0.2043 1.5275 0.0343 1.7417 0.0366</span> +<span class="r-out co"><span class="r-pr">#></span> 54: 93.5781 -6.0412 -0.1166 2.2573 -1.0015 4.4283 3.3411 0.4395 0.2912 0.2080 1.5464 0.0346 1.7584 0.0359</span> +<span class="r-out co"><span class="r-pr">#></span> 55: 93.9675 -6.0867 -0.0952 2.2970 -0.9987 4.2069 3.6762 0.4550 0.2780 0.1988 1.5138 0.0405 1.6251 0.0472</span> +<span class="r-out co"><span class="r-pr">#></span> 56: 94.4069 -6.1375 -0.0943 2.2975 -1.0190 3.9966 4.2280 0.4550 0.2806 0.1945 1.5294 0.0425 1.6443 0.0468</span> +<span class="r-out co"><span class="r-pr">#></span> 57: 93.8076 -6.1618 -0.0936 2.2687 -1.0237 3.7967 4.3085 0.4524 0.2666 0.1897 1.5227 0.0414 1.6955 0.0438</span> +<span class="r-out co"><span class="r-pr">#></span> 58: 93.9188 -6.2272 -0.0947 2.2767 -1.0408 3.6069 4.6707 0.4536 0.2676 0.1873 1.5201 0.0425 1.5336 0.0550</span> +<span class="r-out co"><span class="r-pr">#></span> 59: 93.9572 -6.3460 -0.1074 2.2746 -1.0069 3.4266 5.8058 0.4614 0.2718 0.1919 1.5533 0.0417 1.6227 0.0460</span> +<span class="r-out co"><span class="r-pr">#></span> 60: 93.5430 -6.1622 -0.1048 2.2861 -0.9959 3.2552 5.5155 0.4535 0.2848 0.1823 1.4745 0.0431 1.5242 0.0522</span> +<span class="r-out co"><span class="r-pr">#></span> 61: 93.8016 -6.4079 -0.1065 2.2897 -1.0325 3.0925 5.9252 0.4583 0.2901 0.1732 1.5364 0.0365 1.4623 0.0550</span> +<span class="r-out co"><span class="r-pr">#></span> 62: 93.4249 -6.2284 -0.0967 2.3126 -1.0208 2.9378 5.6289 0.4429 0.2756 0.1645 1.6111 0.0325 1.3996 0.0618</span> +<span class="r-out co"><span class="r-pr">#></span> 63: 93.2335 -6.0996 -0.1051 2.3047 -0.9976 2.7909 5.3475 0.4292 0.2719 0.1633 1.6010 0.0326 1.5115 0.0494</span> +<span class="r-out co"><span class="r-pr">#></span> 64: 92.7091 -6.1109 -0.1041 2.3032 -0.9746 3.2610 5.0801 0.4301 0.2793 0.1751 1.5979 0.0302 1.3867 0.0575</span> +<span class="r-out co"><span class="r-pr">#></span> 65: 92.6059 -6.0049 -0.1077 2.3062 -0.9853 3.0979 4.8261 0.4316 0.2826 0.1714 1.6357 0.0272 1.3931 0.0543</span> +<span class="r-out co"><span class="r-pr">#></span> 66: 92.7778 -6.0856 -0.1040 2.3057 -0.9828 2.9430 4.5848 0.4362 0.2888 0.1628 1.6126 0.0316 1.4340 0.0505</span> +<span class="r-out co"><span class="r-pr">#></span> 67: 93.0325 -6.1775 -0.1085 2.3122 -0.9714 2.7959 4.3790 0.4464 0.2843 0.1547 1.6090 0.0354 1.4966 0.0448</span> +<span class="r-out co"><span class="r-pr">#></span> 68: 92.8987 -5.8741 -0.1089 2.3184 -0.9567 2.6561 4.1601 0.4389 0.2866 0.1470 1.5888 0.0347 1.4492 0.0507</span> +<span class="r-out co"><span class="r-pr">#></span> 69: 92.7300 -6.0473 -0.1070 2.3082 -0.9739 2.5233 4.0183 0.4371 0.3158 0.1527 1.5904 0.0298 1.5387 0.0477</span> +<span class="r-out co"><span class="r-pr">#></span> 70: 92.5285 -6.0962 -0.1115 2.3179 -0.9785 2.4856 4.0612 0.4380 0.3059 0.1504 1.5237 0.0402 1.4541 0.0463</span> +<span class="r-out co"><span class="r-pr">#></span> 71: 92.3975 -6.2090 -0.1269 2.2819 -0.9713 2.3613 4.3811 0.4173 0.2906 0.1520 1.5388 0.0316 1.3713 0.0584</span> +<span class="r-out co"><span class="r-pr">#></span> 72: 92.1593 -6.2214 -0.1217 2.2950 -0.9481 2.2433 5.1205 0.4227 0.2760 0.1605 1.5431 0.0312 1.5797 0.0459</span> +<span class="r-out co"><span class="r-pr">#></span> 73: 92.1195 -6.6667 -0.1244 2.3076 -0.9642 2.1311 7.6538 0.4124 0.2622 0.1525 1.4505 0.0375 1.2810 0.0595</span> +<span class="r-out co"><span class="r-pr">#></span> 74: 92.2191 -6.6665 -0.1278 2.2989 -0.9703 2.0246 7.2711 0.4098 0.2491 0.1666 1.4309 0.0384 1.2717 0.0638</span> +<span class="r-out co"><span class="r-pr">#></span> 75: 92.4656 -6.8881 -0.1274 2.3011 -0.9595 1.9233 8.3835 0.4147 0.2367 0.1656 1.4181 0.0424 1.2498 0.0620</span> +<span class="r-out co"><span class="r-pr">#></span> 76: 92.4593 -6.2323 -0.1203 2.2912 -0.9799 1.8272 7.9643 0.3967 0.2301 0.1596 1.5448 0.0336 1.6758 0.0359</span> +<span class="r-out co"><span class="r-pr">#></span> 77: 92.4501 -6.1123 -0.1219 2.2889 -0.9426 1.7358 7.5661 0.4049 0.2299 0.1594 1.5380 0.0327 1.6947 0.0364</span> +<span class="r-out co"><span class="r-pr">#></span> 78: 92.5059 -6.0339 -0.1198 2.2985 -0.9544 1.6490 7.1878 0.4007 0.2422 0.1568 1.5722 0.0302 1.5665 0.0415</span> +<span class="r-out co"><span class="r-pr">#></span> 79: 92.4302 -6.6428 -0.1141 2.3119 -0.9421 1.5666 9.0889 0.3986 0.2340 0.1489 1.5029 0.0306 1.1894 0.0638</span> +<span class="r-out co"><span class="r-pr">#></span> 80: 92.5305 -6.3036 -0.1127 2.3099 -0.9406 1.9062 8.6344 0.4091 0.2327 0.1648 1.5558 0.0308 1.0136 0.0749</span> +<span class="r-out co"><span class="r-pr">#></span> 81: 92.6652 -6.0832 -0.1167 2.2994 -0.9552 2.3641 8.2027 0.4142 0.2348 0.1566 1.6232 0.0300 1.1320 0.0712</span> +<span class="r-out co"><span class="r-pr">#></span> 82: 92.5109 -6.1524 -0.1100 2.3037 -0.9686 2.2459 7.7926 0.4145 0.2381 0.1695 1.6128 0.0306 1.6145 0.0413</span> +<span class="r-out co"><span class="r-pr">#></span> 83: 92.6455 -6.3979 -0.1059 2.3245 -0.9573 2.1336 8.1077 0.4060 0.2348 0.1667 1.6039 0.0304 1.6251 0.0419</span> +<span class="r-out co"><span class="r-pr">#></span> 84: 92.5768 -6.3469 -0.0979 2.3177 -0.9346 2.0269 8.2125 0.4141 0.2439 0.1720 1.6334 0.0302 1.5803 0.0450</span> +<span class="r-out co"><span class="r-pr">#></span> 85: 92.7920 -6.3536 -0.0969 2.3363 -0.9389 1.9256 8.1820 0.4035 0.2512 0.1713 1.5815 0.0338 1.1193 0.0719</span> +<span class="r-out co"><span class="r-pr">#></span> 86: 92.8571 -6.2567 -0.0911 2.3426 -0.9633 1.8293 8.1211 0.4008 0.2659 0.1627 1.5840 0.0356 1.2425 0.0639</span> +<span class="r-out co"><span class="r-pr">#></span> 87: 92.9101 -6.1557 -0.0937 2.3326 -0.9624 1.7378 7.7151 0.3950 0.2839 0.1546 1.6017 0.0354 1.0600 0.0766</span> +<span class="r-out co"><span class="r-pr">#></span> 88: 92.7649 -6.2151 -0.0881 2.3275 -0.9967 1.6509 7.3293 0.4046 0.2697 0.1469 1.6092 0.0302 1.1839 0.0693</span> +<span class="r-out co"><span class="r-pr">#></span> 89: 92.9350 -5.9222 -0.0903 2.3372 -0.9612 1.5684 6.9628 0.4058 0.2818 0.1395 1.5957 0.0335 1.5450 0.0444</span> +<span class="r-out co"><span class="r-pr">#></span> 90: 92.7895 -5.9348 -0.0890 2.3457 -0.9601 1.4900 6.6147 0.4070 0.2705 0.1430 1.5716 0.0378 1.4918 0.0439</span> +<span class="r-out co"><span class="r-pr">#></span> 91: 93.0113 -5.9302 -0.0997 2.3316 -0.9489 1.4155 6.2840 0.4424 0.2929 0.1410 1.5582 0.0377 1.2459 0.0582</span> +<span class="r-out co"><span class="r-pr">#></span> 92: 92.8603 -6.3366 -0.0918 2.3356 -0.9938 1.3447 5.9698 0.4287 0.2929 0.1531 1.4906 0.0398 1.2421 0.0605</span> +<span class="r-out co"><span class="r-pr">#></span> 93: 92.8094 -6.1097 -0.0953 2.3382 -0.9996 1.2775 5.6713 0.4309 0.2783 0.1597 1.4317 0.0468 1.2694 0.0584</span> +<span class="r-out co"><span class="r-pr">#></span> 94: 92.7100 -6.1043 -0.0909 2.3287 -0.9928 1.3828 5.3877 0.4337 0.2698 0.1517 1.4173 0.0489 1.4335 0.0476</span> +<span class="r-out co"><span class="r-pr">#></span> 95: 92.2055 -6.1792 -0.0889 2.3553 -0.9983 1.3137 5.1183 0.4209 0.3273 0.1566 1.4865 0.0417 1.2485 0.0681</span> +<span class="r-out co"><span class="r-pr">#></span> 96: 92.3225 -6.2710 -0.0811 2.3734 -1.0043 1.3428 4.8624 0.4121 0.3110 0.1532 1.5817 0.0374 1.5209 0.0532</span> +<span class="r-out co"><span class="r-pr">#></span> 97: 92.2983 -6.3023 -0.0776 2.3615 -0.9801 1.2757 4.6193 0.4221 0.3018 0.1455 1.5971 0.0337 1.2137 0.0719</span> +<span class="r-out co"><span class="r-pr">#></span> 98: 92.1433 -6.3114 -0.0935 2.3269 -0.9866 1.2227 4.8121 0.4327 0.2907 0.1694 1.5524 0.0303 1.1779 0.0727</span> +<span class="r-out co"><span class="r-pr">#></span> 99: 92.1631 -6.3090 -0.0908 2.3197 -0.9891 1.1615 4.9271 0.4169 0.2859 0.1736 1.5303 0.0334 1.6227 0.0511</span> +<span class="r-out co"><span class="r-pr">#></span> 100: 92.1185 -6.3603 -0.0950 2.3280 -1.0209 1.1035 5.0957 0.4213 0.2924 0.1817 1.5991 0.0330 1.7197 0.0445</span> +<span class="r-out co"><span class="r-pr">#></span> 101: 92.3964 -6.0447 -0.0898 2.3347 -1.0164 1.0483 4.8409 0.4251 0.2778 0.1727 1.5708 0.0422 1.6197 0.0461</span> +<span class="r-out co"><span class="r-pr">#></span> 102: 92.6597 -6.2545 -0.0954 2.3264 -1.0206 0.9959 4.5989 0.4218 0.2736 0.1640 1.5853 0.0408 1.5912 0.0455</span> +<span class="r-out co"><span class="r-pr">#></span> 103: 92.7866 -6.3292 -0.0933 2.3148 -1.0013 0.9461 4.8935 0.4234 0.2599 0.1688 1.6299 0.0399 1.5921 0.0445</span> +<span class="r-out co"><span class="r-pr">#></span> 104: 92.8098 -6.2608 -0.1009 2.3014 -0.9947 0.8988 4.7750 0.4306 0.2548 0.1813 1.6363 0.0378 1.6713 0.0427</span> +<span class="r-out co"><span class="r-pr">#></span> 105: 92.8300 -5.9827 -0.1028 2.3155 -0.9896 0.8538 4.5362 0.4339 0.2664 0.1722 1.6079 0.0397 1.3691 0.0573</span> +<span class="r-out co"><span class="r-pr">#></span> 106: 92.8218 -6.1138 -0.1024 2.3462 -0.9750 0.8299 4.3094 0.4494 0.2530 0.1636 1.5761 0.0389 1.2857 0.0595</span> +<span class="r-out co"><span class="r-pr">#></span> 107: 92.9304 -6.0063 -0.1002 2.3269 -0.9778 0.7884 4.0939 0.4600 0.2404 0.1620 1.6499 0.0373 1.2101 0.0675</span> +<span class="r-out co"><span class="r-pr">#></span> 108: 92.9072 -6.0928 -0.0991 2.3183 -0.9732 0.7489 4.4394 0.4584 0.2518 0.1539 1.6509 0.0332 1.2346 0.0670</span> +<span class="r-out co"><span class="r-pr">#></span> 109: 92.7504 -6.1545 -0.0862 2.3423 -0.9618 0.7115 4.7501 0.4371 0.2766 0.1465 1.5755 0.0349 1.1552 0.0701</span> +<span class="r-out co"><span class="r-pr">#></span> 110: 92.9277 -6.3786 -0.0904 2.3468 -0.9402 0.6759 5.8620 0.4328 0.2821 0.1703 1.4661 0.0439 1.3292 0.0609</span> +<span class="r-out co"><span class="r-pr">#></span> 111: 92.8023 -5.8686 -0.0886 2.3653 -0.9417 0.7635 5.5689 0.4288 0.2680 0.1618 1.4278 0.0502 1.4715 0.0468</span> +<span class="r-out co"><span class="r-pr">#></span> 112: 92.9411 -5.8095 -0.0883 2.3625 -0.9322 0.8592 5.2905 0.4562 0.2586 0.1537 1.3920 0.0513 1.1766 0.0648</span> +<span class="r-out co"><span class="r-pr">#></span> 113: 92.9845 -6.0499 -0.0761 2.3626 -0.9533 0.8163 5.0259 0.4403 0.2595 0.1532 1.4306 0.0450 1.1416 0.0645</span> +<span class="r-out co"><span class="r-pr">#></span> 114: 92.7735 -6.0605 -0.0694 2.3497 -0.9646 0.7754 4.7746 0.4394 0.2682 0.1576 1.4866 0.0344 1.1127 0.0745</span> +<span class="r-out co"><span class="r-pr">#></span> 115: 92.7048 -6.1327 -0.0702 2.3427 -0.9910 0.7367 4.5359 0.4257 0.2736 0.1497 1.5045 0.0413 1.2783 0.0677</span> +<span class="r-out co"><span class="r-pr">#></span> 116: 92.7131 -6.0115 -0.0751 2.3370 -0.9899 0.6998 4.3091 0.4187 0.2638 0.1422 1.6036 0.0325 1.1109 0.0748</span> +<span class="r-out co"><span class="r-pr">#></span> 117: 92.7720 -5.9163 -0.0709 2.3503 -0.9566 0.6648 4.0937 0.4185 0.2555 0.1417 1.6016 0.0297 1.0778 0.0774</span> +<span class="r-out co"><span class="r-pr">#></span> 118: 92.9182 -5.9312 -0.0812 2.3436 -0.9731 0.6316 3.8890 0.4084 0.2667 0.1400 1.5698 0.0320 1.2364 0.0665</span> +<span class="r-out co"><span class="r-pr">#></span> 119: 92.9546 -5.9622 -0.0870 2.3330 -0.9934 0.6000 3.6945 0.4035 0.2867 0.1486 1.5364 0.0343 1.5892 0.0489</span> +<span class="r-out co"><span class="r-pr">#></span> 120: 92.9168 -6.0966 -0.0905 2.3301 -1.0045 0.5700 3.6677 0.3988 0.2871 0.1567 1.5378 0.0349 1.0886 0.0796</span> +<span class="r-out co"><span class="r-pr">#></span> 121: 92.7767 -6.1038 -0.0802 2.3396 -0.9815 0.5981 4.3032 0.3803 0.2884 0.1684 1.4788 0.0335 1.0886 0.0796</span> +<span class="r-out co"><span class="r-pr">#></span> 122: 92.8439 -6.2425 -0.0799 2.3323 -0.9987 0.6537 4.5745 0.3884 0.2834 0.1600 1.4786 0.0346 1.2146 0.0682</span> +<span class="r-out co"><span class="r-pr">#></span> 123: 92.8219 -5.7869 -0.0872 2.3478 -0.9619 0.7886 4.3458 0.3951 0.2887 0.1658 1.4827 0.0341 1.3911 0.0559</span> +<span class="r-out co"><span class="r-pr">#></span> 124: 92.7930 -5.7551 -0.0819 2.3559 -0.9809 0.8922 4.1285 0.3907 0.2972 0.1575 1.5329 0.0330 1.3824 0.0594</span> +<span class="r-out co"><span class="r-pr">#></span> 125: 92.7488 -5.9406 -0.0819 2.3550 -0.9797 0.8476 3.9221 0.3907 0.2996 0.1733 1.5096 0.0333 1.3148 0.0667</span> +<span class="r-out co"><span class="r-pr">#></span> 126: 92.7926 -5.7106 -0.0824 2.3560 -0.9653 0.8052 3.7260 0.3918 0.3018 0.1854 1.4237 0.0381 1.2607 0.0639</span> +<span class="r-out co"><span class="r-pr">#></span> 127: 92.9153 -5.6682 -0.0717 2.3654 -0.9645 0.7649 3.5397 0.3722 0.2948 0.1784 1.4679 0.0415 1.2310 0.0695</span> +<span class="r-out co"><span class="r-pr">#></span> 128: 92.8827 -5.7984 -0.0783 2.3813 -1.0047 1.1012 3.3627 0.3802 0.2997 0.1694 1.5187 0.0442 1.2884 0.0649</span> +<span class="r-out co"><span class="r-pr">#></span> 129: 92.8727 -5.7191 -0.0785 2.3426 -0.9857 1.0461 3.1946 0.3784 0.2984 0.1610 1.4757 0.0398 1.1695 0.0775</span> +<span class="r-out co"><span class="r-pr">#></span> 130: 92.8689 -5.8036 -0.0935 2.3123 -0.9783 0.9938 3.0348 0.4184 0.2980 0.1723 1.5143 0.0319 1.2298 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 131: 92.8733 -5.6707 -0.0988 2.3045 -0.9936 1.3313 2.8831 0.4277 0.2831 0.1816 1.5919 0.0329 1.5260 0.0533</span> +<span class="r-out co"><span class="r-pr">#></span> 132: 92.5761 -5.7773 -0.0925 2.3211 -0.9661 1.2647 2.7389 0.4216 0.2815 0.1995 1.5306 0.0321 1.5863 0.0520</span> +<span class="r-out co"><span class="r-pr">#></span> 133: 92.4512 -5.7800 -0.0920 2.3269 -0.9625 1.2015 2.6020 0.4242 0.2674 0.1955 1.5669 0.0288 1.4087 0.0606</span> +<span class="r-out co"><span class="r-pr">#></span> 134: 92.5625 -5.7968 -0.0965 2.3271 -0.9728 1.1414 2.4719 0.4201 0.2753 0.1945 1.5935 0.0311 1.5348 0.0534</span> +<span class="r-out co"><span class="r-pr">#></span> 135: 92.3448 -5.6624 -0.0961 2.3303 -0.9600 1.0843 2.3483 0.4193 0.2728 0.1983 1.6245 0.0305 1.6281 0.0506</span> +<span class="r-out co"><span class="r-pr">#></span> 136: 92.3407 -5.7523 -0.0932 2.3208 -0.9897 1.0301 2.3267 0.4107 0.2668 0.1884 1.5933 0.0358 1.2970 0.0657</span> +<span class="r-out co"><span class="r-pr">#></span> 137: 92.3940 -6.0148 -0.1046 2.2981 -0.9866 0.9786 3.1382 0.4166 0.3012 0.1790 1.5077 0.0385 1.1944 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 138: 92.3556 -5.9912 -0.1039 2.2969 -0.9920 0.9297 3.2144 0.4208 0.3039 0.1703 1.5042 0.0378 1.2588 0.0717</span> +<span class="r-out co"><span class="r-pr">#></span> 139: 92.5548 -5.9253 -0.1177 2.2723 -1.0079 0.8832 3.2648 0.4049 0.3263 0.1618 1.5558 0.0382 1.2673 0.0698</span> +<span class="r-out co"><span class="r-pr">#></span> 140: 92.6546 -6.0596 -0.1368 2.2659 -0.9922 0.8390 3.3893 0.3846 0.3100 0.1537 1.5475 0.0355 1.3190 0.0629</span> +<span class="r-out co"><span class="r-pr">#></span> 141: 92.6661 -5.9744 -0.1379 2.2793 -0.9754 0.8287 3.2725 0.3800 0.3178 0.1528 1.5076 0.0361 1.4087 0.0540</span> +<span class="r-out co"><span class="r-pr">#></span> 142: 92.5681 -5.7650 -0.1033 2.3249 -0.9613 0.7872 3.1089 0.3610 0.3564 0.1701 1.4733 0.0332 1.2603 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 143: 92.4184 -5.6070 -0.1033 2.3520 -0.9764 0.7479 2.9534 0.3591 0.3758 0.1674 1.5420 0.0390 1.3280 0.0614</span> +<span class="r-out co"><span class="r-pr">#></span> 144: 92.5354 -5.6144 -0.0978 2.3801 -0.9425 0.7105 2.8058 0.3538 0.3606 0.1722 1.4884 0.0400 1.3455 0.0620</span> +<span class="r-out co"><span class="r-pr">#></span> 145: 92.4207 -5.6541 -0.0746 2.3873 -0.9633 0.6750 2.6655 0.3361 0.3426 0.1718 1.4981 0.0416 1.2440 0.0685</span> +<span class="r-out co"><span class="r-pr">#></span> 146: 92.3058 -5.6608 -0.0731 2.3755 -0.9732 0.6412 2.5322 0.3193 0.3304 0.1719 1.6391 0.0348 1.1788 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 147: 92.4067 -5.7615 -0.0746 2.3775 -0.9903 0.6091 2.4056 0.3148 0.3311 0.1709 1.6695 0.0314 1.2931 0.0676</span> +<span class="r-out co"><span class="r-pr">#></span> 148: 92.3739 -5.8812 -0.0820 2.3644 -0.9823 0.5787 2.7260 0.3332 0.3296 0.1794 1.6168 0.0303 1.3206 0.0670</span> +<span class="r-out co"><span class="r-pr">#></span> 149: 92.4456 -5.8277 -0.0921 2.3508 -0.9924 0.5498 2.8750 0.3368 0.3305 0.1917 1.5602 0.0302 1.3622 0.0608</span> +<span class="r-out co"><span class="r-pr">#></span> 150: 92.5049 -5.7964 -0.1003 2.3353 -0.9809 0.5223 2.7312 0.3291 0.3634 0.1874 1.5035 0.0301 1.4002 0.0615</span> +<span class="r-out co"><span class="r-pr">#></span> 151: 92.3292 -6.0377 -0.1039 2.3301 -0.9866 0.4962 3.3342 0.3348 0.3626 0.1780 1.4819 0.0298 1.3217 0.0672</span> +<span class="r-out co"><span class="r-pr">#></span> 152: 92.3747 -6.0460 -0.1023 2.3154 -1.0242 0.5079 3.4530 0.3371 0.3518 0.1674 1.6034 0.0296 1.2304 0.0749</span> +<span class="r-out co"><span class="r-pr">#></span> 153: 92.3909 -5.8707 -0.1008 2.3284 -0.9897 0.5623 2.8180 0.3480 0.3792 0.1749 1.4953 0.0291 1.3442 0.0677</span> +<span class="r-out co"><span class="r-pr">#></span> 154: 92.2532 -5.9313 -0.0991 2.3232 -0.9839 0.5340 3.3946 0.3502 0.3723 0.1729 1.4837 0.0280 1.1452 0.0776</span> +<span class="r-out co"><span class="r-pr">#></span> 155: 92.1782 -6.1012 -0.0988 2.3339 -0.9600 0.3900 3.9676 0.3593 0.3704 0.1531 1.4927 0.0286 1.1848 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 156: 92.2225 -5.8387 -0.0991 2.3393 -0.9459 0.3294 3.0685 0.3598 0.3808 0.1568 1.5540 0.0318 1.3419 0.0671</span> +<span class="r-out co"><span class="r-pr">#></span> 157: 92.2411 -5.7045 -0.1038 2.3578 -0.9252 0.2797 2.5238 0.3716 0.3579 0.1653 1.4704 0.0373 1.1959 0.0686</span> +<span class="r-out co"><span class="r-pr">#></span> 158: 92.2865 -5.6692 -0.1009 2.3771 -0.9532 0.2840 2.4144 0.3592 0.3610 0.1641 1.5065 0.0389 1.1780 0.0674</span> +<span class="r-out co"><span class="r-pr">#></span> 159: 92.2771 -5.7526 -0.0782 2.3632 -0.9771 0.2996 2.7295 0.3357 0.3779 0.1606 1.5818 0.0366 1.1512 0.0781</span> +<span class="r-out co"><span class="r-pr">#></span> 160: 92.3400 -5.8039 -0.0811 2.3615 -0.9453 0.2707 2.7305 0.3373 0.3834 0.1528 1.4765 0.0370 1.1427 0.0756</span> +<span class="r-out co"><span class="r-pr">#></span> 161: 92.4180 -5.7448 -0.0961 2.3653 -0.9508 0.2965 2.6051 0.3666 0.3833 0.1647 1.4581 0.0364 0.9817 0.0827</span> +<span class="r-out co"><span class="r-pr">#></span> 162: 92.4487 -5.8952 -0.0889 2.3460 -0.9646 0.2370 3.1413 0.3460 0.3801 0.1571 1.4528 0.0346 1.0006 0.0798</span> +<span class="r-out co"><span class="r-pr">#></span> 163: 92.5251 -5.8567 -0.0987 2.3342 -0.9615 0.1453 2.9917 0.3535 0.3735 0.1452 1.4521 0.0330 1.0498 0.0766</span> +<span class="r-out co"><span class="r-pr">#></span> 164: 92.5949 -6.1580 -0.1008 2.3332 -0.9749 0.1095 4.1797 0.3586 0.3767 0.1355 1.4659 0.0310 1.0218 0.0797</span> +<span class="r-out co"><span class="r-pr">#></span> 165: 92.5794 -6.0542 -0.1001 2.3321 -0.9795 0.1332 4.2924 0.3588 0.3752 0.1386 1.4858 0.0313 0.9836 0.0812</span> +<span class="r-out co"><span class="r-pr">#></span> 166: 92.6686 -6.0065 -0.0960 2.3623 -0.9532 0.1465 4.0810 0.3439 0.3683 0.1647 1.3929 0.0372 0.9354 0.0837</span> +<span class="r-out co"><span class="r-pr">#></span> 167: 92.7086 -6.2096 -0.0895 2.3656 -0.9552 0.1938 4.6857 0.3325 0.3519 0.1681 1.4281 0.0362 1.0329 0.0784</span> +<span class="r-out co"><span class="r-pr">#></span> 168: 92.6096 -6.0709 -0.0880 2.3595 -0.9474 0.2141 4.1277 0.3379 0.3527 0.1620 1.4264 0.0347 0.9627 0.0836</span> +<span class="r-out co"><span class="r-pr">#></span> 169: 92.5365 -5.9418 -0.0919 2.3546 -0.9575 0.3620 3.7767 0.3489 0.3589 0.1609 1.4761 0.0360 1.1348 0.0745</span> +<span class="r-out co"><span class="r-pr">#></span> 170: 92.6270 -5.8404 -0.0935 2.3562 -0.9517 0.3312 3.2506 0.3552 0.3607 0.1560 1.4506 0.0383 1.0731 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 171: 92.5606 -5.9213 -0.0899 2.3513 -0.9554 0.4399 3.5587 0.3599 0.3646 0.1385 1.4779 0.0349 0.9844 0.0775</span> +<span class="r-out co"><span class="r-pr">#></span> 172: 92.3630 -5.7066 -0.0765 2.3798 -0.9314 0.5208 2.5578 0.3458 0.3657 0.1547 1.4900 0.0348 1.0485 0.0765</span> +<span class="r-out co"><span class="r-pr">#></span> 173: 92.2527 -5.5811 -0.0713 2.4173 -0.9221 0.8674 2.2100 0.3448 0.3370 0.1513 1.5403 0.0445 1.4403 0.0518</span> +<span class="r-out co"><span class="r-pr">#></span> 174: 92.3852 -5.5348 -0.0712 2.4066 -0.9033 0.7543 2.1568 0.3457 0.3324 0.1482 1.5322 0.0407 1.2744 0.0623</span> +<span class="r-out co"><span class="r-pr">#></span> 175: 92.4798 -5.5494 -0.0712 2.4004 -0.9100 0.5675 2.0147 0.3457 0.3333 0.1629 1.5229 0.0383 1.2917 0.0655</span> +<span class="r-out co"><span class="r-pr">#></span> 176: 92.5881 -5.5613 -0.0675 2.4180 -0.9188 0.4011 2.0736 0.3413 0.3487 0.1781 1.5149 0.0389 1.1499 0.0669</span> +<span class="r-out co"><span class="r-pr">#></span> 177: 92.6015 -5.4951 -0.0494 2.4324 -0.9525 0.4992 1.9009 0.3629 0.3353 0.1919 1.4881 0.0393 1.2289 0.0650</span> +<span class="r-out co"><span class="r-pr">#></span> 178: 92.6317 -5.4943 -0.0505 2.4373 -0.9298 0.5087 1.6116 0.3631 0.3324 0.1906 1.4475 0.0454 1.0764 0.0701</span> +<span class="r-out co"><span class="r-pr">#></span> 179: 92.7043 -5.5326 -0.0419 2.4386 -0.9376 0.4350 1.8241 0.3577 0.3757 0.1991 1.4445 0.0424 0.9626 0.0833</span> +<span class="r-out co"><span class="r-pr">#></span> 180: 92.7457 -5.5591 -0.0371 2.4684 -0.9450 0.3973 1.7797 0.3507 0.3707 0.1944 1.4392 0.0415 1.0784 0.0764</span> +<span class="r-out co"><span class="r-pr">#></span> 181: 92.6287 -5.5741 -0.0368 2.4489 -0.9459 0.4744 1.8016 0.3502 0.3544 0.1970 1.4317 0.0392 0.9225 0.0848</span> +<span class="r-out co"><span class="r-pr">#></span> 182: 92.6121 -5.5593 -0.0316 2.4610 -0.9345 0.6054 1.9206 0.3492 0.3538 0.1855 1.4410 0.0367 0.8977 0.0878</span> +<span class="r-out co"><span class="r-pr">#></span> 183: 92.4258 -5.4737 -0.0393 2.4592 -0.9319 0.8062 1.7845 0.3528 0.3544 0.1649 1.4545 0.0409 1.0723 0.0751</span> +<span class="r-out co"><span class="r-pr">#></span> 184: 92.3939 -5.5961 -0.0479 2.4268 -0.9435 1.0246 2.2534 0.3497 0.3289 0.1363 1.5022 0.0370 1.1058 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 185: 92.4673 -5.5415 -0.0525 2.4157 -0.9058 0.8296 2.2848 0.3406 0.3314 0.1706 1.4935 0.0367 1.1362 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 186: 92.4122 -5.6594 -0.0574 2.4466 -0.9430 0.9133 2.3350 0.3327 0.3596 0.1506 1.4450 0.0404 1.2273 0.0629</span> +<span class="r-out co"><span class="r-pr">#></span> 187: 92.5416 -5.5472 -0.0521 2.4393 -0.9261 0.9731 1.9228 0.3208 0.3673 0.1421 1.4890 0.0409 1.2553 0.0626</span> +<span class="r-out co"><span class="r-pr">#></span> 188: 92.5502 -5.6425 -0.0591 2.4345 -0.9246 0.9315 2.2041 0.3184 0.3639 0.1319 1.4896 0.0392 1.0986 0.0684</span> +<span class="r-out co"><span class="r-pr">#></span> 189: 92.4180 -5.6737 -0.0504 2.4448 -0.9191 0.9006 2.4647 0.3102 0.3743 0.1648 1.4649 0.0397 1.1320 0.0742</span> +<span class="r-out co"><span class="r-pr">#></span> 190: 92.5821 -5.5823 -0.0363 2.4588 -0.9205 0.9862 2.2692 0.2820 0.4087 0.1459 1.3938 0.0412 0.9562 0.0815</span> +<span class="r-out co"><span class="r-pr">#></span> 191: 92.3708 -5.5825 -0.0418 2.4621 -0.9231 0.9867 2.4743 0.2890 0.4196 0.1445 1.4619 0.0403 0.9630 0.0811</span> +<span class="r-out co"><span class="r-pr">#></span> 192: 92.2628 -5.5337 -0.0366 2.4392 -0.9194 0.6944 2.2771 0.2909 0.4169 0.1279 1.4745 0.0363 0.8601 0.0892</span> +<span class="r-out co"><span class="r-pr">#></span> 193: 92.4854 -5.6303 -0.0352 2.4484 -0.9316 0.4403 2.3253 0.2928 0.4109 0.1282 1.4768 0.0399 0.8886 0.0871</span> +<span class="r-out co"><span class="r-pr">#></span> 194: 92.4900 -5.5824 -0.0372 2.4648 -0.9451 0.4891 2.6428 0.2899 0.4160 0.1331 1.5124 0.0412 0.9340 0.0853</span> +<span class="r-out co"><span class="r-pr">#></span> 195: 92.4685 -5.7658 -0.0357 2.4659 -0.9217 0.4549 3.3767 0.2921 0.4171 0.1552 1.5062 0.0396 1.0336 0.0817</span> +<span class="r-out co"><span class="r-pr">#></span> 196: 92.4125 -5.7544 -0.0255 2.4834 -0.9230 0.4146 3.1963 0.3000 0.4369 0.1501 1.4560 0.0430 0.9942 0.0813</span> +<span class="r-out co"><span class="r-pr">#></span> 197: 92.3284 -5.9347 -0.0305 2.4860 -0.9448 0.4115 3.5642 0.3129 0.4314 0.1740 1.3441 0.0473 1.0954 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 198: 92.3428 -5.9255 -0.0266 2.4822 -0.9463 0.3258 3.4818 0.3185 0.4163 0.1716 1.3868 0.0447 0.9452 0.0788</span> +<span class="r-out co"><span class="r-pr">#></span> 199: 92.1692 -6.0683 -0.0227 2.4860 -0.9495 0.2685 4.4044 0.3149 0.4064 0.1824 1.3558 0.0478 1.0294 0.0749</span> +<span class="r-out co"><span class="r-pr">#></span> 200: 92.0965 -6.1541 -0.0261 2.4793 -0.9288 0.2210 4.4026 0.3265 0.4200 0.1772 1.3348 0.0441 1.0018 0.0761</span> +<span class="r-out co"><span class="r-pr">#></span> 201: 92.1362 -6.1170 -0.0244 2.4776 -0.9237 0.1801 4.4160 0.3276 0.4303 0.1732 1.3479 0.0418 0.9419 0.0809</span> +<span class="r-out co"><span class="r-pr">#></span> 202: 92.1114 -6.0898 -0.0233 2.4862 -0.9253 0.1506 4.4494 0.3286 0.4305 0.1656 1.3473 0.0440 0.9394 0.0802</span> +<span class="r-out co"><span class="r-pr">#></span> 203: 92.0893 -6.1307 -0.0233 2.4894 -0.9258 0.1510 4.7958 0.3310 0.4233 0.1673 1.3396 0.0457 0.9617 0.0788</span> +<span class="r-out co"><span class="r-pr">#></span> 204: 92.0870 -6.0914 -0.0230 2.4867 -0.9234 0.1589 4.6265 0.3316 0.4237 0.1643 1.3478 0.0456 0.9509 0.0793</span> +<span class="r-out co"><span class="r-pr">#></span> 205: 92.0800 -6.0960 -0.0228 2.4867 -0.9256 0.1613 4.6319 0.3321 0.4226 0.1623 1.3399 0.0463 0.9547 0.0789</span> +<span class="r-out co"><span class="r-pr">#></span> 206: 92.1037 -6.0869 -0.0238 2.4833 -0.9264 0.1648 4.5547 0.3341 0.4186 0.1606 1.3351 0.0466 0.9453 0.0797</span> +<span class="r-out co"><span class="r-pr">#></span> 207: 92.1212 -6.0561 -0.0247 2.4821 -0.9299 0.1677 4.3736 0.3363 0.4150 0.1602 1.3394 0.0467 0.9552 0.0790</span> +<span class="r-out co"><span class="r-pr">#></span> 208: 92.1203 -6.0351 -0.0260 2.4804 -0.9309 0.1616 4.2520 0.3369 0.4120 0.1613 1.3366 0.0466 0.9667 0.0785</span> +<span class="r-out co"><span class="r-pr">#></span> 209: 92.1169 -6.0133 -0.0277 2.4792 -0.9300 0.1596 4.1237 0.3352 0.4111 0.1616 1.3344 0.0464 0.9741 0.0778</span> +<span class="r-out co"><span class="r-pr">#></span> 210: 92.1195 -5.9866 -0.0289 2.4752 -0.9287 0.1586 3.9853 0.3352 0.4091 0.1602 1.3410 0.0461 0.9708 0.0778</span> +<span class="r-out co"><span class="r-pr">#></span> 211: 92.1243 -5.9458 -0.0316 2.4687 -0.9287 0.1606 3.8383 0.3366 0.4094 0.1607 1.3525 0.0455 0.9759 0.0778</span> +<span class="r-out co"><span class="r-pr">#></span> 212: 92.1384 -5.9338 -0.0345 2.4640 -0.9280 0.1635 3.7875 0.3375 0.4105 0.1594 1.3589 0.0454 0.9800 0.0776</span> +<span class="r-out co"><span class="r-pr">#></span> 213: 92.1481 -5.9191 -0.0379 2.4587 -0.9269 0.1629 3.7150 0.3375 0.4100 0.1586 1.3673 0.0449 0.9839 0.0775</span> +<span class="r-out co"><span class="r-pr">#></span> 214: 92.1523 -5.9189 -0.0408 2.4542 -0.9270 0.1593 3.7061 0.3375 0.4092 0.1579 1.3731 0.0446 0.9847 0.0773</span> +<span class="r-out co"><span class="r-pr">#></span> 215: 92.1548 -5.9183 -0.0429 2.4499 -0.9269 0.1604 3.7075 0.3369 0.4095 0.1574 1.3765 0.0442 0.9821 0.0775</span> +<span class="r-out co"><span class="r-pr">#></span> 216: 92.1547 -5.9171 -0.0450 2.4455 -0.9270 0.1600 3.6967 0.3368 0.4100 0.1571 1.3811 0.0438 0.9830 0.0776</span> +<span class="r-out co"><span class="r-pr">#></span> 217: 92.1556 -5.9141 -0.0468 2.4422 -0.9281 0.1580 3.6732 0.3361 0.4102 0.1578 1.3864 0.0435 0.9995 0.0770</span> +<span class="r-out co"><span class="r-pr">#></span> 218: 92.1587 -5.9173 -0.0477 2.4395 -0.9287 0.1545 3.6822 0.3351 0.4112 0.1580 1.3882 0.0432 1.0001 0.0772</span> +<span class="r-out co"><span class="r-pr">#></span> 219: 92.1590 -5.9188 -0.0483 2.4374 -0.9303 0.1540 3.6595 0.3341 0.4132 0.1578 1.3889 0.0430 0.9983 0.0775</span> +<span class="r-out co"><span class="r-pr">#></span> 220: 92.1614 -5.9303 -0.0493 2.4353 -0.9321 0.1559 3.6914 0.3336 0.4141 0.1581 1.3914 0.0427 1.0003 0.0775</span> +<span class="r-out co"><span class="r-pr">#></span> 221: 92.1657 -5.9455 -0.0504 2.4328 -0.9344 0.1585 3.7569 0.3329 0.4140 0.1591 1.3938 0.0424 1.0064 0.0773</span> +<span class="r-out co"><span class="r-pr">#></span> 222: 92.1697 -5.9320 -0.0515 2.4306 -0.9358 0.1617 3.6783 0.3321 0.4145 0.1600 1.3992 0.0421 1.0107 0.0772</span> +<span class="r-out co"><span class="r-pr">#></span> 223: 92.1754 -5.9205 -0.0525 2.4280 -0.9375 0.1630 3.6233 0.3313 0.4158 0.1604 1.4072 0.0416 1.0216 0.0770</span> +<span class="r-out co"><span class="r-pr">#></span> 224: 92.1809 -5.9149 -0.0534 2.4264 -0.9386 0.1623 3.5812 0.3306 0.4167 0.1607 1.4130 0.0413 1.0349 0.0764</span> +<span class="r-out co"><span class="r-pr">#></span> 225: 92.1872 -5.9099 -0.0543 2.4243 -0.9390 0.1619 3.5446 0.3299 0.4174 0.1607 1.4152 0.0411 1.0348 0.0766</span> +<span class="r-out co"><span class="r-pr">#></span> 226: 92.1935 -5.9046 -0.0554 2.4224 -0.9396 0.1631 3.5046 0.3299 0.4183 0.1608 1.4157 0.0409 1.0375 0.0766</span> +<span class="r-out co"><span class="r-pr">#></span> 227: 92.2026 -5.8964 -0.0567 2.4198 -0.9400 0.1637 3.4591 0.3303 0.4183 0.1614 1.4144 0.0408 1.0444 0.0763</span> +<span class="r-out co"><span class="r-pr">#></span> 228: 92.2069 -5.8852 -0.0578 2.4175 -0.9407 0.1633 3.4091 0.3308 0.4185 0.1621 1.4144 0.0407 1.0485 0.0763</span> +<span class="r-out co"><span class="r-pr">#></span> 229: 92.2122 -5.8844 -0.0591 2.4145 -0.9418 0.1631 3.3899 0.3314 0.4194 0.1622 1.4173 0.0404 1.0514 0.0763</span> +<span class="r-out co"><span class="r-pr">#></span> 230: 92.2183 -5.8907 -0.0604 2.4116 -0.9416 0.1640 3.4053 0.3319 0.4202 0.1616 1.4200 0.0401 1.0527 0.0764</span> +<span class="r-out co"><span class="r-pr">#></span> 231: 92.2246 -5.8895 -0.0619 2.4087 -0.9422 0.1651 3.3985 0.3323 0.4208 0.1609 1.4234 0.0400 1.0560 0.0762</span> +<span class="r-out co"><span class="r-pr">#></span> 232: 92.2282 -5.8840 -0.0632 2.4058 -0.9423 0.1641 3.3771 0.3327 0.4215 0.1609 1.4266 0.0398 1.0585 0.0762</span> +<span class="r-out co"><span class="r-pr">#></span> 233: 92.2294 -5.8775 -0.0645 2.4032 -0.9424 0.1620 3.3481 0.3335 0.4216 0.1607 1.4311 0.0395 1.0600 0.0763</span> +<span class="r-out co"><span class="r-pr">#></span> 234: 92.2311 -5.8709 -0.0658 2.4006 -0.9421 0.1626 3.3242 0.3343 0.4220 0.1602 1.4340 0.0393 1.0604 0.0764</span> +<span class="r-out co"><span class="r-pr">#></span> 235: 92.2312 -5.8656 -0.0668 2.3985 -0.9420 0.1608 3.3023 0.3350 0.4225 0.1596 1.4381 0.0391 1.0600 0.0765</span> +<span class="r-out co"><span class="r-pr">#></span> 236: 92.2289 -5.8633 -0.0675 2.3974 -0.9423 0.1599 3.2811 0.3352 0.4227 0.1589 1.4392 0.0390 1.0594 0.0765</span> +<span class="r-out co"><span class="r-pr">#></span> 237: 92.2251 -5.8641 -0.0683 2.3960 -0.9435 0.1586 3.2734 0.3351 0.4226 0.1588 1.4403 0.0389 1.0623 0.0765</span> +<span class="r-out co"><span class="r-pr">#></span> 238: 92.2242 -5.8633 -0.0690 2.3949 -0.9443 0.1579 3.2547 0.3349 0.4230 0.1590 1.4409 0.0389 1.0659 0.0765</span> +<span class="r-out co"><span class="r-pr">#></span> 239: 92.2250 -5.8612 -0.0693 2.3951 -0.9449 0.1558 3.2309 0.3346 0.4234 0.1599 1.4396 0.0389 1.0740 0.0762</span> +<span class="r-out co"><span class="r-pr">#></span> 240: 92.2264 -5.8597 -0.0696 2.3949 -0.9446 0.1550 3.2124 0.3342 0.4234 0.1603 1.4401 0.0388 1.0791 0.0760</span> +<span class="r-out co"><span class="r-pr">#></span> 241: 92.2281 -5.8562 -0.0699 2.3948 -0.9449 0.1544 3.1933 0.3339 0.4236 0.1604 1.4411 0.0388 1.0825 0.0760</span> +<span class="r-out co"><span class="r-pr">#></span> 242: 92.2289 -5.8512 -0.0703 2.3942 -0.9450 0.1534 3.1709 0.3338 0.4235 0.1606 1.4421 0.0388 1.0870 0.0760</span> +<span class="r-out co"><span class="r-pr">#></span> 243: 92.2296 -5.8489 -0.0708 2.3934 -0.9446 0.1531 3.1689 0.3342 0.4230 0.1605 1.4423 0.0387 1.0876 0.0760</span> +<span class="r-out co"><span class="r-pr">#></span> 244: 92.2311 -5.8446 -0.0715 2.3929 -0.9443 0.1528 3.1630 0.3349 0.4228 0.1604 1.4429 0.0387 1.0916 0.0759</span> +<span class="r-out co"><span class="r-pr">#></span> 245: 92.2338 -5.8421 -0.0718 2.3924 -0.9443 0.1528 3.1616 0.3352 0.4224 0.1610 1.4438 0.0387 1.0980 0.0755</span> +<span class="r-out co"><span class="r-pr">#></span> 246: 92.2361 -5.8389 -0.0721 2.3918 -0.9439 0.1525 3.1525 0.3354 0.4216 0.1620 1.4438 0.0388 1.1018 0.0753</span> +<span class="r-out co"><span class="r-pr">#></span> 247: 92.2374 -5.8388 -0.0724 2.3917 -0.9434 0.1510 3.1605 0.3356 0.4212 0.1629 1.4438 0.0389 1.1050 0.0751</span> +<span class="r-out co"><span class="r-pr">#></span> 248: 92.2360 -5.8367 -0.0728 2.3918 -0.9432 0.1505 3.1559 0.3360 0.4207 0.1638 1.4437 0.0389 1.1090 0.0748</span> +<span class="r-out co"><span class="r-pr">#></span> 249: 92.2361 -5.8351 -0.0732 2.3914 -0.9435 0.1499 3.1521 0.3363 0.4204 0.1646 1.4433 0.0389 1.1117 0.0748</span> +<span class="r-out co"><span class="r-pr">#></span> 250: 92.2353 -5.8349 -0.0733 2.3906 -0.9436 0.1502 3.1607 0.3365 0.4202 0.1646 1.4457 0.0388 1.1107 0.0749</span> +<span class="r-out co"><span class="r-pr">#></span> 251: 92.2343 -5.8318 -0.0736 2.3903 -0.9430 0.1494 3.1513 0.3367 0.4201 0.1648 1.4453 0.0387 1.1093 0.0750</span> +<span class="r-out co"><span class="r-pr">#></span> 252: 92.2356 -5.8244 -0.0739 2.3895 -0.9424 0.1477 3.1240 0.3369 0.4200 0.1651 1.4460 0.0386 1.1083 0.0750</span> +<span class="r-out co"><span class="r-pr">#></span> 253: 92.2367 -5.8188 -0.0742 2.3890 -0.9423 0.1465 3.1025 0.3369 0.4200 0.1649 1.4477 0.0385 1.1092 0.0750</span> +<span class="r-out co"><span class="r-pr">#></span> 254: 92.2392 -5.8154 -0.0747 2.3880 -0.9421 0.1458 3.0888 0.3372 0.4195 0.1644 1.4494 0.0384 1.1080 0.0750</span> +<span class="r-out co"><span class="r-pr">#></span> 255: 92.2404 -5.8131 -0.0751 2.3870 -0.9417 0.1451 3.0778 0.3375 0.4191 0.1639 1.4501 0.0383 1.1070 0.0751</span> +<span class="r-out co"><span class="r-pr">#></span> 256: 92.2408 -5.8109 -0.0753 2.3867 -0.9413 0.1445 3.0740 0.3376 0.4192 0.1633 1.4510 0.0382 1.1064 0.0751</span> +<span class="r-out co"><span class="r-pr">#></span> 257: 92.2413 -5.8066 -0.0754 2.3866 -0.9409 0.1446 3.0636 0.3376 0.4191 0.1628 1.4522 0.0382 1.1080 0.0750</span> +<span class="r-out co"><span class="r-pr">#></span> 258: 92.2412 -5.8035 -0.0754 2.3869 -0.9404 0.1436 3.0502 0.3372 0.4191 0.1623 1.4534 0.0381 1.1057 0.0751</span> +<span class="r-out co"><span class="r-pr">#></span> 259: 92.2399 -5.7996 -0.0753 2.3871 -0.9399 0.1427 3.0357 0.3370 0.4195 0.1621 1.4540 0.0380 1.1037 0.0752</span> +<span class="r-out co"><span class="r-pr">#></span> 260: 92.2389 -5.7955 -0.0755 2.3872 -0.9391 0.1420 3.0251 0.3366 0.4199 0.1619 1.4555 0.0380 1.1041 0.0752</span> +<span class="r-out co"><span class="r-pr">#></span> 261: 92.2378 -5.7941 -0.0755 2.3875 -0.9385 0.1412 3.0240 0.3362 0.4201 0.1613 1.4575 0.0380 1.1048 0.0751</span> +<span class="r-out co"><span class="r-pr">#></span> 262: 92.2361 -5.7920 -0.0756 2.3879 -0.9379 0.1407 3.0182 0.3358 0.4205 0.1607 1.4581 0.0381 1.1047 0.0750</span> +<span class="r-out co"><span class="r-pr">#></span> 263: 92.2338 -5.7891 -0.0754 2.3883 -0.9375 0.1407 3.0072 0.3356 0.4211 0.1603 1.4585 0.0381 1.1041 0.0750</span> +<span class="r-out co"><span class="r-pr">#></span> 264: 92.2313 -5.7882 -0.0752 2.3886 -0.9371 0.1407 3.0009 0.3355 0.4217 0.1601 1.4574 0.0381 1.1036 0.0750</span> +<span class="r-out co"><span class="r-pr">#></span> 265: 92.2312 -5.7843 -0.0752 2.3883 -0.9372 0.1402 2.9872 0.3358 0.4220 0.1599 1.4577 0.0381 1.1026 0.0750</span> +<span class="r-out co"><span class="r-pr">#></span> 266: 92.2312 -5.7800 -0.0753 2.3880 -0.9370 0.1396 2.9708 0.3363 0.4223 0.1597 1.4584 0.0381 1.1019 0.0750</span> +<span class="r-out co"><span class="r-pr">#></span> 267: 92.2306 -5.7785 -0.0755 2.3878 -0.9372 0.1397 2.9619 0.3368 0.4227 0.1595 1.4578 0.0381 1.1021 0.0750</span> +<span class="r-out co"><span class="r-pr">#></span> 268: 92.2287 -5.7803 -0.0758 2.3870 -0.9372 0.1394 2.9777 0.3375 0.4226 0.1594 1.4578 0.0380 1.1032 0.0749</span> +<span class="r-out co"><span class="r-pr">#></span> 269: 92.2265 -5.7804 -0.0761 2.3865 -0.9371 0.1399 2.9816 0.3382 0.4226 0.1592 1.4589 0.0380 1.1058 0.0747</span> +<span class="r-out co"><span class="r-pr">#></span> 270: 92.2236 -5.7811 -0.0765 2.3860 -0.9369 0.1411 2.9893 0.3386 0.4227 0.1591 1.4597 0.0380 1.1081 0.0745</span> +<span class="r-out co"><span class="r-pr">#></span> 271: 92.2211 -5.7793 -0.0769 2.3852 -0.9365 0.1421 2.9888 0.3390 0.4228 0.1591 1.4606 0.0379 1.1083 0.0745</span> +<span class="r-out co"><span class="r-pr">#></span> 272: 92.2187 -5.7773 -0.0773 2.3845 -0.9361 0.1423 2.9810 0.3396 0.4232 0.1589 1.4617 0.0378 1.1076 0.0746</span> +<span class="r-out co"><span class="r-pr">#></span> 273: 92.2164 -5.7769 -0.0776 2.3838 -0.9356 0.1427 2.9809 0.3402 0.4240 0.1589 1.4615 0.0378 1.1073 0.0746</span> +<span class="r-out co"><span class="r-pr">#></span> 274: 92.2145 -5.7763 -0.0778 2.3836 -0.9355 0.1434 2.9795 0.3407 0.4248 0.1589 1.4615 0.0378 1.1069 0.0746</span> +<span class="r-out co"><span class="r-pr">#></span> 275: 92.2133 -5.7762 -0.0779 2.3836 -0.9352 0.1436 2.9837 0.3410 0.4253 0.1589 1.4621 0.0378 1.1064 0.0746</span> +<span class="r-out co"><span class="r-pr">#></span> 276: 92.2123 -5.7764 -0.0781 2.3835 -0.9348 0.1431 2.9889 0.3414 0.4255 0.1589 1.4632 0.0378 1.1073 0.0746</span> +<span class="r-out co"><span class="r-pr">#></span> 277: 92.2113 -5.7771 -0.0781 2.3839 -0.9347 0.1423 2.9925 0.3423 0.4264 0.1589 1.4630 0.0378 1.1104 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 278: 92.2099 -5.7774 -0.0780 2.3841 -0.9349 0.1418 2.9927 0.3429 0.4270 0.1590 1.4634 0.0378 1.1127 0.0742</span> +<span class="r-out co"><span class="r-pr">#></span> 279: 92.2087 -5.7798 -0.0779 2.3844 -0.9352 0.1413 2.9997 0.3437 0.4276 0.1590 1.4630 0.0378 1.1133 0.0742</span> +<span class="r-out co"><span class="r-pr">#></span> 280: 92.2077 -5.7802 -0.0778 2.3841 -0.9358 0.1407 2.9971 0.3445 0.4284 0.1586 1.4634 0.0378 1.1136 0.0742</span> +<span class="r-out co"><span class="r-pr">#></span> 281: 92.2061 -5.7814 -0.0777 2.3837 -0.9362 0.1401 3.0004 0.3452 0.4291 0.1582 1.4629 0.0378 1.1133 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 282: 92.2058 -5.7802 -0.0777 2.3834 -0.9363 0.1386 2.9994 0.3459 0.4297 0.1579 1.4634 0.0378 1.1126 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 283: 92.2057 -5.7780 -0.0778 2.3828 -0.9361 0.1376 2.9917 0.3469 0.4298 0.1576 1.4645 0.0378 1.1147 0.0742</span> +<span class="r-out co"><span class="r-pr">#></span> 284: 92.2051 -5.7788 -0.0780 2.3824 -0.9360 0.1367 2.9968 0.3479 0.4300 0.1573 1.4647 0.0378 1.1149 0.0741</span> +<span class="r-out co"><span class="r-pr">#></span> 285: 92.2041 -5.7793 -0.0782 2.3821 -0.9362 0.1359 2.9941 0.3487 0.4302 0.1573 1.4653 0.0378 1.1164 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 286: 92.2040 -5.7803 -0.0783 2.3819 -0.9364 0.1352 2.9957 0.3495 0.4304 0.1573 1.4655 0.0378 1.1180 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 287: 92.2044 -5.7809 -0.0784 2.3817 -0.9365 0.1348 2.9961 0.3502 0.4304 0.1572 1.4657 0.0379 1.1178 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 288: 92.2043 -5.7835 -0.0785 2.3814 -0.9366 0.1350 3.0073 0.3509 0.4304 0.1572 1.4658 0.0379 1.1184 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 289: 92.2041 -5.7845 -0.0787 2.3809 -0.9364 0.1347 3.0126 0.3516 0.4304 0.1571 1.4653 0.0379 1.1190 0.0737</span> +<span class="r-out co"><span class="r-pr">#></span> 290: 92.2032 -5.7852 -0.0788 2.3807 -0.9363 0.1349 3.0161 0.3521 0.4304 0.1568 1.4656 0.0379 1.1191 0.0737</span> +<span class="r-out co"><span class="r-pr">#></span> 291: 92.2019 -5.7848 -0.0790 2.3802 -0.9363 0.1356 3.0155 0.3528 0.4300 0.1565 1.4664 0.0380 1.1210 0.0736</span> +<span class="r-out co"><span class="r-pr">#></span> 292: 92.2012 -5.7846 -0.0792 2.3799 -0.9363 0.1361 3.0167 0.3535 0.4296 0.1563 1.4670 0.0380 1.1223 0.0735</span> +<span class="r-out co"><span class="r-pr">#></span> 293: 92.2007 -5.7845 -0.0793 2.3795 -0.9363 0.1365 3.0175 0.3542 0.4291 0.1561 1.4681 0.0380 1.1236 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 294: 92.2009 -5.7850 -0.0795 2.3791 -0.9360 0.1365 3.0189 0.3550 0.4287 0.1560 1.4682 0.0380 1.1243 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 295: 92.2009 -5.7865 -0.0797 2.3786 -0.9360 0.1360 3.0279 0.3556 0.4286 0.1558 1.4689 0.0380 1.1243 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 296: 92.2007 -5.7878 -0.0798 2.3781 -0.9362 0.1358 3.0345 0.3562 0.4283 0.1555 1.4694 0.0379 1.1247 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 297: 92.1992 -5.7891 -0.0801 2.3774 -0.9364 0.1358 3.0403 0.3568 0.4278 0.1554 1.4699 0.0379 1.1267 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 298: 92.1978 -5.7892 -0.0803 2.3768 -0.9366 0.1357 3.0383 0.3573 0.4274 0.1553 1.4706 0.0378 1.1276 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 299: 92.1968 -5.7906 -0.0805 2.3763 -0.9369 0.1353 3.0408 0.3579 0.4269 0.1553 1.4712 0.0378 1.1282 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 300: 92.1954 -5.7929 -0.0807 2.3760 -0.9369 0.1352 3.0477 0.3583 0.4265 0.1551 1.4716 0.0379 1.1286 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 301: 92.1941 -5.7934 -0.0809 2.3757 -0.9369 0.1352 3.0483 0.3588 0.4261 0.1548 1.4727 0.0378 1.1288 0.0732</span> +<span class="r-out co"><span class="r-pr">#></span> 302: 92.1929 -5.7949 -0.0811 2.3754 -0.9370 0.1354 3.0560 0.3592 0.4256 0.1548 1.4728 0.0379 1.1296 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 303: 92.1919 -5.7972 -0.0813 2.3751 -0.9368 0.1352 3.0671 0.3597 0.4250 0.1550 1.4730 0.0379 1.1302 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 304: 92.1906 -5.8018 -0.0814 2.3750 -0.9368 0.1349 3.0935 0.3602 0.4245 0.1552 1.4731 0.0379 1.1314 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 305: 92.1897 -5.8063 -0.0817 2.3744 -0.9370 0.1350 3.1211 0.3606 0.4238 0.1554 1.4727 0.0379 1.1323 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 306: 92.1896 -5.8116 -0.0820 2.3740 -0.9373 0.1347 3.1571 0.3610 0.4233 0.1555 1.4727 0.0379 1.1351 0.0728</span> +<span class="r-out co"><span class="r-pr">#></span> 307: 92.1895 -5.8156 -0.0822 2.3735 -0.9373 0.1341 3.1826 0.3613 0.4226 0.1552 1.4741 0.0379 1.1374 0.0726</span> +<span class="r-out co"><span class="r-pr">#></span> 308: 92.1899 -5.8202 -0.0824 2.3732 -0.9376 0.1338 3.2124 0.3617 0.4220 0.1554 1.4745 0.0379 1.1408 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 309: 92.1903 -5.8232 -0.0827 2.3728 -0.9377 0.1337 3.2330 0.3620 0.4213 0.1554 1.4749 0.0379 1.1419 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 310: 92.1902 -5.8249 -0.0828 2.3727 -0.9378 0.1335 3.2463 0.3621 0.4207 0.1554 1.4752 0.0379 1.1435 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 311: 92.1910 -5.8267 -0.0828 2.3726 -0.9378 0.1335 3.2581 0.3623 0.4200 0.1554 1.4754 0.0379 1.1441 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 312: 92.1918 -5.8271 -0.0829 2.3726 -0.9378 0.1333 3.2567 0.3624 0.4195 0.1552 1.4751 0.0380 1.1432 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 313: 92.1926 -5.8260 -0.0829 2.3725 -0.9380 0.1334 3.2497 0.3626 0.4190 0.1552 1.4751 0.0380 1.1434 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 314: 92.1934 -5.8256 -0.0829 2.3724 -0.9381 0.1330 3.2426 0.3628 0.4185 0.1553 1.4746 0.0380 1.1441 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 315: 92.1938 -5.8237 -0.0829 2.3724 -0.9384 0.1326 3.2327 0.3630 0.4179 0.1555 1.4746 0.0380 1.1468 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 316: 92.1950 -5.8235 -0.0829 2.3722 -0.9385 0.1324 3.2283 0.3631 0.4172 0.1557 1.4745 0.0380 1.1476 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 317: 92.1963 -5.8239 -0.0829 2.3722 -0.9385 0.1322 3.2260 0.3633 0.4167 0.1560 1.4741 0.0380 1.1481 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 318: 92.1975 -5.8242 -0.0829 2.3722 -0.9387 0.1321 3.2240 0.3634 0.4163 0.1559 1.4740 0.0380 1.1477 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 319: 92.1990 -5.8250 -0.0829 2.3721 -0.9387 0.1320 3.2215 0.3634 0.4159 0.1560 1.4736 0.0381 1.1496 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 320: 92.2003 -5.8256 -0.0829 2.3722 -0.9386 0.1322 3.2199 0.3635 0.4155 0.1561 1.4730 0.0381 1.1508 0.0719</span> +<span class="r-out co"><span class="r-pr">#></span> 321: 92.2018 -5.8249 -0.0829 2.3723 -0.9386 0.1326 3.2150 0.3635 0.4151 0.1562 1.4727 0.0381 1.1514 0.0718</span> +<span class="r-out co"><span class="r-pr">#></span> 322: 92.2031 -5.8239 -0.0829 2.3724 -0.9386 0.1333 3.2081 0.3635 0.4147 0.1561 1.4729 0.0381 1.1527 0.0717</span> +<span class="r-out co"><span class="r-pr">#></span> 323: 92.2045 -5.8244 -0.0829 2.3725 -0.9384 0.1336 3.2065 0.3635 0.4143 0.1562 1.4729 0.0381 1.1541 0.0716</span> +<span class="r-out co"><span class="r-pr">#></span> 324: 92.2060 -5.8228 -0.0828 2.3726 -0.9383 0.1339 3.1996 0.3635 0.4139 0.1562 1.4729 0.0382 1.1562 0.0714</span> +<span class="r-out co"><span class="r-pr">#></span> 325: 92.2071 -5.8212 -0.0828 2.3727 -0.9383 0.1339 3.1921 0.3636 0.4135 0.1563 1.4733 0.0382 1.1580 0.0713</span> +<span class="r-out co"><span class="r-pr">#></span> 326: 92.2083 -5.8201 -0.0826 2.3728 -0.9382 0.1340 3.1888 0.3639 0.4134 0.1562 1.4734 0.0382 1.1587 0.0713</span> +<span class="r-out co"><span class="r-pr">#></span> 327: 92.2095 -5.8185 -0.0825 2.3729 -0.9379 0.1340 3.1831 0.3641 0.4134 0.1562 1.4737 0.0382 1.1592 0.0713</span> +<span class="r-out co"><span class="r-pr">#></span> 328: 92.2105 -5.8188 -0.0823 2.3731 -0.9379 0.1338 3.1836 0.3643 0.4132 0.1561 1.4736 0.0383 1.1589 0.0713</span> +<span class="r-out co"><span class="r-pr">#></span> 329: 92.2115 -5.8182 -0.0821 2.3732 -0.9381 0.1339 3.1807 0.3646 0.4129 0.1561 1.4737 0.0383 1.1585 0.0713</span> +<span class="r-out co"><span class="r-pr">#></span> 330: 92.2127 -5.8181 -0.0819 2.3734 -0.9381 0.1338 3.1827 0.3648 0.4127 0.1563 1.4735 0.0383 1.1578 0.0714</span> +<span class="r-out co"><span class="r-pr">#></span> 331: 92.2134 -5.8180 -0.0815 2.3739 -0.9381 0.1340 3.1837 0.3647 0.4128 0.1566 1.4735 0.0383 1.1575 0.0714</span> +<span class="r-out co"><span class="r-pr">#></span> 332: 92.2136 -5.8184 -0.0811 2.3746 -0.9379 0.1340 3.1847 0.3647 0.4130 0.1570 1.4728 0.0384 1.1577 0.0714</span> +<span class="r-out co"><span class="r-pr">#></span> 333: 92.2133 -5.8180 -0.0807 2.3753 -0.9376 0.1340 3.1853 0.3646 0.4132 0.1572 1.4725 0.0384 1.1573 0.0714</span> +<span class="r-out co"><span class="r-pr">#></span> 334: 92.2136 -5.8173 -0.0803 2.3760 -0.9374 0.1342 3.1838 0.3645 0.4133 0.1576 1.4720 0.0385 1.1570 0.0714</span> +<span class="r-out co"><span class="r-pr">#></span> 335: 92.2139 -5.8187 -0.0800 2.3769 -0.9372 0.1344 3.1947 0.3643 0.4135 0.1576 1.4714 0.0386 1.1567 0.0714</span> +<span class="r-out co"><span class="r-pr">#></span> 336: 92.2134 -5.8198 -0.0796 2.3777 -0.9370 0.1348 3.2008 0.3641 0.4135 0.1577 1.4706 0.0387 1.1557 0.0714</span> +<span class="r-out co"><span class="r-pr">#></span> 337: 92.2130 -5.8201 -0.0792 2.3784 -0.9370 0.1357 3.2050 0.3640 0.4137 0.1579 1.4703 0.0388 1.1558 0.0714</span> +<span class="r-out co"><span class="r-pr">#></span> 338: 92.2130 -5.8190 -0.0787 2.3791 -0.9368 0.1362 3.2036 0.3638 0.4139 0.1580 1.4708 0.0388 1.1558 0.0714</span> +<span class="r-out co"><span class="r-pr">#></span> 339: 92.2132 -5.8177 -0.0783 2.3798 -0.9368 0.1369 3.2006 0.3637 0.4142 0.1581 1.4712 0.0388 1.1551 0.0714</span> +<span class="r-out co"><span class="r-pr">#></span> 340: 92.2137 -5.8167 -0.0778 2.3806 -0.9366 0.1376 3.1984 0.3636 0.4143 0.1581 1.4712 0.0388 1.1540 0.0715</span> +<span class="r-out co"><span class="r-pr">#></span> 341: 92.2141 -5.8145 -0.0773 2.3814 -0.9364 0.1378 3.1916 0.3635 0.4142 0.1581 1.4712 0.0389 1.1529 0.0715</span> +<span class="r-out co"><span class="r-pr">#></span> 342: 92.2142 -5.8123 -0.0769 2.3821 -0.9364 0.1383 3.1840 0.3634 0.4142 0.1581 1.4718 0.0389 1.1513 0.0716</span> +<span class="r-out co"><span class="r-pr">#></span> 343: 92.2139 -5.8109 -0.0764 2.3830 -0.9364 0.1389 3.1806 0.3632 0.4142 0.1581 1.4721 0.0389 1.1501 0.0716</span> +<span class="r-out co"><span class="r-pr">#></span> 344: 92.2137 -5.8117 -0.0759 2.3839 -0.9366 0.1390 3.1830 0.3631 0.4144 0.1582 1.4711 0.0390 1.1492 0.0717</span> +<span class="r-out co"><span class="r-pr">#></span> 345: 92.2133 -5.8118 -0.0754 2.3849 -0.9368 0.1391 3.1827 0.3630 0.4146 0.1582 1.4703 0.0391 1.1488 0.0717</span> +<span class="r-out co"><span class="r-pr">#></span> 346: 92.2127 -5.8113 -0.0748 2.3858 -0.9369 0.1389 3.1793 0.3629 0.4147 0.1581 1.4700 0.0391 1.1475 0.0717</span> +<span class="r-out co"><span class="r-pr">#></span> 347: 92.2121 -5.8107 -0.0743 2.3867 -0.9371 0.1386 3.1748 0.3628 0.4149 0.1579 1.4701 0.0392 1.1463 0.0718</span> +<span class="r-out co"><span class="r-pr">#></span> 348: 92.2106 -5.8109 -0.0738 2.3876 -0.9374 0.1385 3.1726 0.3626 0.4151 0.1577 1.4704 0.0392 1.1453 0.0719</span> +<span class="r-out co"><span class="r-pr">#></span> 349: 92.2096 -5.8111 -0.0732 2.3883 -0.9377 0.1382 3.1703 0.3626 0.4151 0.1575 1.4705 0.0392 1.1448 0.0719</span> +<span class="r-out co"><span class="r-pr">#></span> 350: 92.2088 -5.8108 -0.0727 2.3890 -0.9378 0.1380 3.1674 0.3625 0.4152 0.1574 1.4704 0.0392 1.1439 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 351: 92.2077 -5.8103 -0.0722 2.3899 -0.9379 0.1379 3.1634 0.3623 0.4154 0.1572 1.4701 0.0393 1.1432 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 352: 92.2069 -5.8103 -0.0718 2.3906 -0.9381 0.1380 3.1626 0.3623 0.4154 0.1570 1.4701 0.0393 1.1425 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 353: 92.2058 -5.8107 -0.0714 2.3913 -0.9381 0.1382 3.1629 0.3624 0.4154 0.1570 1.4695 0.0394 1.1426 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 354: 92.2046 -5.8102 -0.0710 2.3921 -0.9381 0.1384 3.1576 0.3624 0.4154 0.1571 1.4691 0.0394 1.1424 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 355: 92.2034 -5.8084 -0.0707 2.3928 -0.9381 0.1388 3.1501 0.3624 0.4154 0.1570 1.4686 0.0395 1.1414 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 356: 92.2027 -5.8079 -0.0703 2.3935 -0.9382 0.1392 3.1463 0.3626 0.4155 0.1569 1.4682 0.0396 1.1405 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 357: 92.2019 -5.8084 -0.0698 2.3943 -0.9382 0.1390 3.1444 0.3628 0.4156 0.1569 1.4665 0.0397 1.1403 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 358: 92.2014 -5.8085 -0.0694 2.3950 -0.9381 0.1389 3.1413 0.3630 0.4158 0.1569 1.4662 0.0398 1.1398 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 359: 92.2005 -5.8091 -0.0689 2.3956 -0.9383 0.1387 3.1393 0.3633 0.4159 0.1570 1.4664 0.0398 1.1401 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 360: 92.1994 -5.8091 -0.0685 2.3962 -0.9385 0.1385 3.1362 0.3635 0.4159 0.1572 1.4664 0.0398 1.1413 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 361: 92.1983 -5.8094 -0.0682 2.3966 -0.9386 0.1384 3.1340 0.3638 0.4159 0.1573 1.4669 0.0398 1.1420 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 362: 92.1976 -5.8086 -0.0678 2.3971 -0.9389 0.1380 3.1277 0.3639 0.4160 0.1573 1.4671 0.0398 1.1414 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 363: 92.1967 -5.8081 -0.0675 2.3976 -0.9389 0.1377 3.1239 0.3641 0.4161 0.1573 1.4669 0.0399 1.1412 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 364: 92.1960 -5.8073 -0.0671 2.3982 -0.9390 0.1373 3.1208 0.3643 0.4161 0.1572 1.4668 0.0399 1.1411 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 365: 92.1958 -5.8066 -0.0667 2.3988 -0.9389 0.1369 3.1164 0.3645 0.4160 0.1572 1.4672 0.0399 1.1416 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 366: 92.1956 -5.8063 -0.0664 2.3992 -0.9390 0.1364 3.1127 0.3650 0.4156 0.1573 1.4674 0.0399 1.1425 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 367: 92.1952 -5.8056 -0.0661 2.3996 -0.9389 0.1361 3.1082 0.3652 0.4155 0.1574 1.4675 0.0399 1.1416 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 368: 92.1948 -5.8059 -0.0658 2.4001 -0.9389 0.1359 3.1068 0.3655 0.4154 0.1575 1.4671 0.0399 1.1406 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 369: 92.1948 -5.8064 -0.0655 2.4005 -0.9388 0.1360 3.1055 0.3658 0.4152 0.1576 1.4669 0.0399 1.1408 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 370: 92.1951 -5.8072 -0.0652 2.4010 -0.9389 0.1361 3.1060 0.3660 0.4151 0.1576 1.4669 0.0399 1.1406 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 371: 92.1956 -5.8080 -0.0649 2.4015 -0.9390 0.1362 3.1095 0.3662 0.4150 0.1576 1.4669 0.0400 1.1411 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 372: 92.1962 -5.8096 -0.0645 2.4020 -0.9390 0.1363 3.1168 0.3665 0.4149 0.1576 1.4667 0.0400 1.1411 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 373: 92.1968 -5.8098 -0.0642 2.4025 -0.9392 0.1363 3.1154 0.3666 0.4147 0.1576 1.4664 0.0400 1.1418 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 374: 92.1972 -5.8098 -0.0640 2.4029 -0.9395 0.1363 3.1117 0.3667 0.4146 0.1576 1.4661 0.0401 1.1421 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 375: 92.1979 -5.8101 -0.0637 2.4032 -0.9397 0.1364 3.1090 0.3668 0.4143 0.1577 1.4654 0.0401 1.1425 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 376: 92.1981 -5.8106 -0.0635 2.4035 -0.9399 0.1363 3.1084 0.3669 0.4142 0.1576 1.4650 0.0401 1.1423 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 377: 92.1986 -5.8104 -0.0633 2.4039 -0.9399 0.1360 3.1053 0.3670 0.4142 0.1576 1.4645 0.0402 1.1424 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 378: 92.1989 -5.8104 -0.0631 2.4043 -0.9399 0.1358 3.1026 0.3671 0.4142 0.1577 1.4638 0.0402 1.1421 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 379: 92.1990 -5.8114 -0.0628 2.4047 -0.9399 0.1355 3.1068 0.3671 0.4141 0.1577 1.4636 0.0402 1.1413 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 380: 92.1989 -5.8119 -0.0627 2.4048 -0.9400 0.1351 3.1095 0.3673 0.4136 0.1577 1.4634 0.0402 1.1413 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 381: 92.1989 -5.8127 -0.0627 2.4048 -0.9400 0.1349 3.1152 0.3676 0.4131 0.1577 1.4631 0.0403 1.1408 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 382: 92.1994 -5.8126 -0.0627 2.4049 -0.9399 0.1348 3.1188 0.3678 0.4126 0.1576 1.4635 0.0403 1.1403 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 383: 92.2000 -5.8129 -0.0626 2.4049 -0.9397 0.1346 3.1256 0.3681 0.4120 0.1576 1.4637 0.0403 1.1396 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 384: 92.2006 -5.8133 -0.0626 2.4050 -0.9396 0.1347 3.1290 0.3683 0.4115 0.1575 1.4641 0.0402 1.1389 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 385: 92.2015 -5.8131 -0.0626 2.4050 -0.9394 0.1350 3.1287 0.3686 0.4110 0.1575 1.4642 0.0402 1.1382 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 386: 92.2023 -5.8140 -0.0625 2.4049 -0.9391 0.1349 3.1324 0.3690 0.4104 0.1574 1.4647 0.0402 1.1374 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 387: 92.2030 -5.8147 -0.0625 2.4050 -0.9390 0.1349 3.1345 0.3693 0.4099 0.1572 1.4652 0.0402 1.1366 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 388: 92.2040 -5.8157 -0.0625 2.4050 -0.9389 0.1349 3.1381 0.3696 0.4094 0.1570 1.4652 0.0402 1.1362 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 389: 92.2051 -5.8156 -0.0625 2.4051 -0.9387 0.1349 3.1373 0.3699 0.4090 0.1570 1.4653 0.0402 1.1354 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 390: 92.2063 -5.8152 -0.0625 2.4051 -0.9386 0.1349 3.1350 0.3702 0.4087 0.1570 1.4655 0.0402 1.1345 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 391: 92.2076 -5.8160 -0.0625 2.4051 -0.9384 0.1350 3.1380 0.3705 0.4083 0.1571 1.4656 0.0402 1.1341 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 392: 92.2086 -5.8166 -0.0626 2.4049 -0.9384 0.1349 3.1397 0.3707 0.4081 0.1572 1.4658 0.0402 1.1345 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 393: 92.2095 -5.8168 -0.0626 2.4047 -0.9383 0.1348 3.1405 0.3708 0.4080 0.1573 1.4659 0.0402 1.1344 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 394: 92.2107 -5.8174 -0.0627 2.4045 -0.9382 0.1347 3.1433 0.3710 0.4079 0.1575 1.4660 0.0401 1.1342 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 395: 92.2118 -5.8174 -0.0628 2.4043 -0.9380 0.1346 3.1437 0.3711 0.4078 0.1575 1.4661 0.0401 1.1343 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 396: 92.2127 -5.8170 -0.0629 2.4041 -0.9379 0.1344 3.1424 0.3712 0.4077 0.1575 1.4664 0.0401 1.1342 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 397: 92.2137 -5.8161 -0.0630 2.4040 -0.9376 0.1342 3.1386 0.3713 0.4076 0.1577 1.4667 0.0401 1.1341 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 398: 92.2146 -5.8152 -0.0633 2.4036 -0.9374 0.1341 3.1344 0.3713 0.4075 0.1578 1.4671 0.0401 1.1334 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 399: 92.2157 -5.8138 -0.0635 2.4032 -0.9373 0.1340 3.1296 0.3714 0.4074 0.1578 1.4678 0.0401 1.1336 0.0726</span> +<span class="r-out co"><span class="r-pr">#></span> 400: 92.2165 -5.8131 -0.0638 2.4027 -0.9372 0.1340 3.1262 0.3715 0.4072 0.1579 1.4681 0.0400 1.1332 0.0726</span> +<span class="r-out co"><span class="r-pr">#></span> 401: 92.2173 -5.8118 -0.0641 2.4022 -0.9372 0.1341 3.1220 0.3716 0.4069 0.1579 1.4686 0.0400 1.1339 0.0726</span> +<span class="r-out co"><span class="r-pr">#></span> 402: 92.2181 -5.8107 -0.0643 2.4018 -0.9370 0.1344 3.1192 0.3718 0.4065 0.1580 1.4694 0.0400 1.1338 0.0726</span> +<span class="r-out co"><span class="r-pr">#></span> 403: 92.2190 -5.8099 -0.0646 2.4013 -0.9371 0.1348 3.1166 0.3720 0.4061 0.1581 1.4700 0.0400 1.1344 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 404: 92.2198 -5.8104 -0.0649 2.4008 -0.9372 0.1348 3.1161 0.3723 0.4058 0.1582 1.4704 0.0399 1.1357 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 405: 92.2203 -5.8107 -0.0652 2.4004 -0.9372 0.1348 3.1177 0.3725 0.4055 0.1582 1.4705 0.0400 1.1358 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 406: 92.2204 -5.8103 -0.0653 2.4002 -0.9371 0.1348 3.1157 0.3724 0.4051 0.1582 1.4709 0.0400 1.1361 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 407: 92.2201 -5.8094 -0.0655 2.4001 -0.9369 0.1348 3.1121 0.3724 0.4048 0.1583 1.4713 0.0400 1.1360 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 408: 92.2201 -5.8087 -0.0657 2.3999 -0.9368 0.1350 3.1085 0.3724 0.4044 0.1582 1.4714 0.0400 1.1360 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 409: 92.2201 -5.8083 -0.0658 2.3998 -0.9365 0.1355 3.1073 0.3724 0.4043 0.1582 1.4713 0.0401 1.1358 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 410: 92.2196 -5.8094 -0.0659 2.3996 -0.9365 0.1361 3.1123 0.3724 0.4041 0.1582 1.4712 0.0401 1.1357 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 411: 92.2192 -5.8099 -0.0661 2.3994 -0.9366 0.1363 3.1168 0.3724 0.4038 0.1582 1.4715 0.0401 1.1354 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 412: 92.2187 -5.8105 -0.0662 2.3993 -0.9365 0.1365 3.1215 0.3725 0.4035 0.1582 1.4716 0.0401 1.1359 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 413: 92.2185 -5.8109 -0.0663 2.3992 -0.9365 0.1367 3.1268 0.3725 0.4031 0.1583 1.4719 0.0401 1.1357 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 414: 92.2183 -5.8111 -0.0665 2.3987 -0.9365 0.1370 3.1286 0.3727 0.4026 0.1582 1.4724 0.0400 1.1349 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 415: 92.2181 -5.8122 -0.0667 2.3983 -0.9366 0.1370 3.1351 0.3729 0.4021 0.1581 1.4726 0.0400 1.1341 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 416: 92.2180 -5.8133 -0.0669 2.3979 -0.9367 0.1372 3.1409 0.3731 0.4015 0.1578 1.4734 0.0400 1.1333 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 417: 92.2176 -5.8138 -0.0671 2.3976 -0.9368 0.1374 3.1426 0.3733 0.4009 0.1576 1.4739 0.0400 1.1325 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 418: 92.2173 -5.8150 -0.0673 2.3973 -0.9369 0.1376 3.1479 0.3735 0.4003 0.1575 1.4740 0.0400 1.1316 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 419: 92.2174 -5.8154 -0.0674 2.3970 -0.9369 0.1375 3.1497 0.3736 0.3998 0.1574 1.4741 0.0400 1.1314 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 420: 92.2175 -5.8154 -0.0676 2.3968 -0.9369 0.1375 3.1489 0.3737 0.3993 0.1574 1.4742 0.0400 1.1315 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 421: 92.2176 -5.8154 -0.0678 2.3964 -0.9369 0.1374 3.1485 0.3739 0.3989 0.1573 1.4743 0.0400 1.1312 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 422: 92.2174 -5.8155 -0.0680 2.3961 -0.9370 0.1375 3.1483 0.3741 0.3985 0.1572 1.4744 0.0400 1.1309 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 423: 92.2170 -5.8156 -0.0681 2.3958 -0.9371 0.1375 3.1481 0.3742 0.3980 0.1571 1.4741 0.0400 1.1308 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 424: 92.2169 -5.8168 -0.0683 2.3956 -0.9372 0.1374 3.1524 0.3744 0.3976 0.1571 1.4740 0.0400 1.1316 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 425: 92.2167 -5.8171 -0.0685 2.3954 -0.9372 0.1373 3.1520 0.3744 0.3972 0.1571 1.4736 0.0401 1.1317 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 426: 92.2164 -5.8170 -0.0687 2.3951 -0.9372 0.1373 3.1502 0.3745 0.3968 0.1570 1.4734 0.0401 1.1320 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 427: 92.2166 -5.8169 -0.0688 2.3949 -0.9372 0.1372 3.1480 0.3745 0.3964 0.1570 1.4734 0.0401 1.1317 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 428: 92.2166 -5.8170 -0.0689 2.3948 -0.9374 0.1371 3.1460 0.3745 0.3959 0.1570 1.4735 0.0401 1.1315 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 429: 92.2162 -5.8171 -0.0691 2.3946 -0.9374 0.1369 3.1446 0.3745 0.3954 0.1570 1.4736 0.0401 1.1316 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 430: 92.2158 -5.8178 -0.0692 2.3944 -0.9375 0.1370 3.1464 0.3745 0.3950 0.1570 1.4736 0.0401 1.1314 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 431: 92.2153 -5.8180 -0.0693 2.3942 -0.9375 0.1371 3.1470 0.3745 0.3946 0.1570 1.4735 0.0401 1.1314 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 432: 92.2150 -5.8182 -0.0695 2.3940 -0.9375 0.1372 3.1477 0.3746 0.3942 0.1570 1.4735 0.0401 1.1315 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 433: 92.2145 -5.8189 -0.0696 2.3938 -0.9375 0.1374 3.1512 0.3746 0.3938 0.1571 1.4736 0.0400 1.1323 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 434: 92.2141 -5.8186 -0.0697 2.3936 -0.9373 0.1376 3.1530 0.3746 0.3933 0.1571 1.4736 0.0400 1.1330 0.0719</span> +<span class="r-out co"><span class="r-pr">#></span> 435: 92.2133 -5.8187 -0.0699 2.3934 -0.9373 0.1381 3.1571 0.3747 0.3929 0.1570 1.4738 0.0400 1.1325 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 436: 92.2129 -5.8180 -0.0700 2.3932 -0.9374 0.1380 3.1544 0.3746 0.3925 0.1570 1.4740 0.0400 1.1332 0.0719</span> +<span class="r-out co"><span class="r-pr">#></span> 437: 92.2122 -5.8186 -0.0702 2.3930 -0.9375 0.1380 3.1574 0.3746 0.3921 0.1570 1.4739 0.0400 1.1342 0.0718</span> +<span class="r-out co"><span class="r-pr">#></span> 438: 92.2114 -5.8187 -0.0703 2.3928 -0.9376 0.1380 3.1583 0.3745 0.3918 0.1569 1.4740 0.0400 1.1346 0.0718</span> +<span class="r-out co"><span class="r-pr">#></span> 439: 92.2104 -5.8181 -0.0705 2.3925 -0.9377 0.1381 3.1568 0.3744 0.3914 0.1568 1.4743 0.0400 1.1352 0.0718</span> +<span class="r-out co"><span class="r-pr">#></span> 440: 92.2095 -5.8178 -0.0706 2.3923 -0.9377 0.1381 3.1555 0.3743 0.3910 0.1566 1.4745 0.0400 1.1349 0.0718</span> +<span class="r-out co"><span class="r-pr">#></span> 441: 92.2088 -5.8176 -0.0707 2.3923 -0.9378 0.1381 3.1559 0.3742 0.3907 0.1565 1.4748 0.0400 1.1349 0.0718</span> +<span class="r-out co"><span class="r-pr">#></span> 442: 92.2081 -5.8172 -0.0708 2.3921 -0.9379 0.1383 3.1539 0.3741 0.3903 0.1564 1.4754 0.0400 1.1350 0.0717</span> +<span class="r-out co"><span class="r-pr">#></span> 443: 92.2074 -5.8171 -0.0709 2.3920 -0.9380 0.1387 3.1526 0.3740 0.3901 0.1563 1.4756 0.0400 1.1349 0.0717</span> +<span class="r-out co"><span class="r-pr">#></span> 444: 92.2068 -5.8175 -0.0711 2.3918 -0.9380 0.1390 3.1533 0.3739 0.3898 0.1562 1.4758 0.0400 1.1353 0.0717</span> +<span class="r-out co"><span class="r-pr">#></span> 445: 92.2061 -5.8180 -0.0712 2.3915 -0.9382 0.1394 3.1529 0.3737 0.3896 0.1562 1.4758 0.0400 1.1355 0.0717</span> +<span class="r-out co"><span class="r-pr">#></span> 446: 92.2054 -5.8177 -0.0714 2.3912 -0.9384 0.1398 3.1496 0.3735 0.3894 0.1562 1.4760 0.0399 1.1367 0.0716</span> +<span class="r-out co"><span class="r-pr">#></span> 447: 92.2051 -5.8180 -0.0716 2.3910 -0.9385 0.1400 3.1484 0.3734 0.3891 0.1563 1.4762 0.0399 1.1370 0.0715</span> +<span class="r-out co"><span class="r-pr">#></span> 448: 92.2053 -5.8189 -0.0717 2.3909 -0.9387 0.1405 3.1499 0.3732 0.3889 0.1563 1.4764 0.0399 1.1377 0.0715</span> +<span class="r-out co"><span class="r-pr">#></span> 449: 92.2054 -5.8195 -0.0718 2.3908 -0.9388 0.1411 3.1497 0.3730 0.3887 0.1562 1.4768 0.0399 1.1382 0.0715</span> +<span class="r-out co"><span class="r-pr">#></span> 450: 92.2054 -5.8205 -0.0719 2.3906 -0.9390 0.1417 3.1528 0.3728 0.3885 0.1562 1.4769 0.0399 1.1378 0.0715</span> +<span class="r-out co"><span class="r-pr">#></span> 451: 92.2053 -5.8213 -0.0720 2.3905 -0.9391 0.1423 3.1544 0.3725 0.3883 0.1561 1.4774 0.0399 1.1379 0.0715</span> +<span class="r-out co"><span class="r-pr">#></span> 452: 92.2054 -5.8218 -0.0720 2.3905 -0.9393 0.1426 3.1541 0.3722 0.3882 0.1560 1.4779 0.0398 1.1378 0.0715</span> +<span class="r-out co"><span class="r-pr">#></span> 453: 92.2054 -5.8217 -0.0721 2.3903 -0.9395 0.1428 3.1530 0.3721 0.3880 0.1559 1.4785 0.0398 1.1378 0.0715</span> +<span class="r-out co"><span class="r-pr">#></span> 454: 92.2053 -5.8214 -0.0722 2.3901 -0.9395 0.1431 3.1508 0.3720 0.3878 0.1559 1.4786 0.0398 1.1375 0.0715</span> +<span class="r-out co"><span class="r-pr">#></span> 455: 92.2052 -5.8220 -0.0724 2.3898 -0.9396 0.1433 3.1519 0.3720 0.3875 0.1559 1.4791 0.0398 1.1379 0.0715</span> +<span class="r-out co"><span class="r-pr">#></span> 456: 92.2053 -5.8230 -0.0727 2.3894 -0.9397 0.1434 3.1544 0.3720 0.3873 0.1560 1.4793 0.0398 1.1384 0.0714</span> +<span class="r-out co"><span class="r-pr">#></span> 457: 92.2053 -5.8240 -0.0729 2.3889 -0.9398 0.1437 3.1568 0.3720 0.3869 0.1559 1.4793 0.0398 1.1393 0.0714</span> +<span class="r-out co"><span class="r-pr">#></span> 458: 92.2051 -5.8245 -0.0731 2.3885 -0.9399 0.1440 3.1571 0.3721 0.3865 0.1558 1.4797 0.0397 1.1404 0.0713</span> +<span class="r-out co"><span class="r-pr">#></span> 459: 92.2045 -5.8246 -0.0732 2.3882 -0.9402 0.1442 3.1562 0.3721 0.3862 0.1558 1.4801 0.0397 1.1407 0.0713</span> +<span class="r-out co"><span class="r-pr">#></span> 460: 92.2040 -5.8244 -0.0734 2.3878 -0.9403 0.1442 3.1536 0.3722 0.3859 0.1558 1.4806 0.0397 1.1406 0.0713</span> +<span class="r-out co"><span class="r-pr">#></span> 461: 92.2030 -5.8245 -0.0736 2.3874 -0.9404 0.1444 3.1517 0.3722 0.3856 0.1557 1.4811 0.0397 1.1412 0.0713</span> +<span class="r-out co"><span class="r-pr">#></span> 462: 92.2022 -5.8253 -0.0738 2.3870 -0.9405 0.1445 3.1531 0.3723 0.3853 0.1556 1.4817 0.0396 1.1425 0.0712</span> +<span class="r-out co"><span class="r-pr">#></span> 463: 92.2014 -5.8260 -0.0740 2.3866 -0.9405 0.1449 3.1545 0.3724 0.3849 0.1556 1.4823 0.0396 1.1441 0.0711</span> +<span class="r-out co"><span class="r-pr">#></span> 464: 92.2008 -5.8257 -0.0742 2.3862 -0.9405 0.1453 3.1522 0.3726 0.3845 0.1555 1.4828 0.0396 1.1451 0.0711</span> +<span class="r-out co"><span class="r-pr">#></span> 465: 92.2002 -5.8256 -0.0744 2.3859 -0.9404 0.1458 3.1511 0.3727 0.3842 0.1555 1.4830 0.0396 1.1459 0.0710</span> +<span class="r-out co"><span class="r-pr">#></span> 466: 92.1997 -5.8256 -0.0747 2.3855 -0.9403 0.1463 3.1516 0.3728 0.3839 0.1555 1.4834 0.0396 1.1476 0.0709</span> +<span class="r-out co"><span class="r-pr">#></span> 467: 92.1993 -5.8258 -0.0749 2.3850 -0.9404 0.1468 3.1521 0.3730 0.3836 0.1555 1.4835 0.0395 1.1490 0.0708</span> +<span class="r-out co"><span class="r-pr">#></span> 468: 92.1990 -5.8259 -0.0752 2.3846 -0.9404 0.1473 3.1546 0.3731 0.3834 0.1555 1.4837 0.0395 1.1500 0.0708</span> +<span class="r-out co"><span class="r-pr">#></span> 469: 92.1987 -5.8263 -0.0753 2.3844 -0.9403 0.1479 3.1598 0.3731 0.3831 0.1555 1.4839 0.0395 1.1504 0.0707</span> +<span class="r-out co"><span class="r-pr">#></span> 470: 92.1987 -5.8267 -0.0755 2.3841 -0.9403 0.1482 3.1611 0.3730 0.3829 0.1555 1.4839 0.0395 1.1496 0.0708</span> +<span class="r-out co"><span class="r-pr">#></span> 471: 92.1987 -5.8269 -0.0756 2.3839 -0.9404 0.1482 3.1627 0.3730 0.3826 0.1555 1.4839 0.0395 1.1492 0.0708</span> +<span class="r-out co"><span class="r-pr">#></span> 472: 92.1983 -5.8269 -0.0758 2.3838 -0.9403 0.1480 3.1618 0.3729 0.3823 0.1555 1.4839 0.0395 1.1493 0.0708</span> +<span class="r-out co"><span class="r-pr">#></span> 473: 92.1980 -5.8264 -0.0760 2.3836 -0.9402 0.1478 3.1602 0.3728 0.3820 0.1554 1.4839 0.0395 1.1489 0.0708</span> +<span class="r-out co"><span class="r-pr">#></span> 474: 92.1976 -5.8256 -0.0762 2.3834 -0.9402 0.1475 3.1565 0.3727 0.3818 0.1554 1.4842 0.0395 1.1487 0.0708</span> +<span class="r-out co"><span class="r-pr">#></span> 475: 92.1971 -5.8252 -0.0763 2.3832 -0.9402 0.1473 3.1543 0.3726 0.3816 0.1553 1.4845 0.0395 1.1487 0.0707</span> +<span class="r-out co"><span class="r-pr">#></span> 476: 92.1965 -5.8250 -0.0765 2.3830 -0.9402 0.1469 3.1523 0.3725 0.3814 0.1552 1.4846 0.0395 1.1484 0.0707</span> +<span class="r-out co"><span class="r-pr">#></span> 477: 92.1960 -5.8242 -0.0766 2.3827 -0.9402 0.1465 3.1483 0.3724 0.3811 0.1552 1.4849 0.0395 1.1483 0.0708</span> +<span class="r-out co"><span class="r-pr">#></span> 478: 92.1955 -5.8236 -0.0767 2.3826 -0.9402 0.1463 3.1447 0.3722 0.3808 0.1553 1.4854 0.0395 1.1481 0.0708</span> +<span class="r-out co"><span class="r-pr">#></span> 479: 92.1952 -5.8232 -0.0769 2.3824 -0.9401 0.1462 3.1421 0.3722 0.3805 0.1554 1.4857 0.0395 1.1478 0.0708</span> +<span class="r-out co"><span class="r-pr">#></span> 480: 92.1948 -5.8235 -0.0770 2.3822 -0.9400 0.1461 3.1426 0.3721 0.3803 0.1554 1.4862 0.0395 1.1478 0.0708</span> +<span class="r-out co"><span class="r-pr">#></span> 481: 92.1947 -5.8240 -0.0772 2.3820 -0.9399 0.1459 3.1455 0.3721 0.3801 0.1554 1.4868 0.0395 1.1483 0.0708</span> +<span class="r-out co"><span class="r-pr">#></span> 482: 92.1948 -5.8244 -0.0774 2.3817 -0.9399 0.1456 3.1476 0.3720 0.3799 0.1553 1.4873 0.0395 1.1488 0.0708</span> +<span class="r-out co"><span class="r-pr">#></span> 483: 92.1944 -5.8247 -0.0776 2.3815 -0.9397 0.1455 3.1487 0.3719 0.3797 0.1553 1.4876 0.0394 1.1494 0.0708</span> +<span class="r-out co"><span class="r-pr">#></span> 484: 92.1941 -5.8249 -0.0778 2.3811 -0.9396 0.1454 3.1493 0.3719 0.3795 0.1554 1.4879 0.0394 1.1501 0.0707</span> +<span class="r-out co"><span class="r-pr">#></span> 485: 92.1940 -5.8252 -0.0780 2.3809 -0.9396 0.1453 3.1501 0.3718 0.3793 0.1554 1.4881 0.0394 1.1503 0.0707</span> +<span class="r-out co"><span class="r-pr">#></span> 486: 92.1936 -5.8249 -0.0781 2.3807 -0.9395 0.1453 3.1486 0.3717 0.3792 0.1554 1.4884 0.0394 1.1508 0.0707</span> +<span class="r-out co"><span class="r-pr">#></span> 487: 92.1935 -5.8248 -0.0783 2.3804 -0.9394 0.1453 3.1485 0.3716 0.3791 0.1553 1.4887 0.0393 1.1507 0.0707</span> +<span class="r-out co"><span class="r-pr">#></span> 488: 92.1932 -5.8246 -0.0785 2.3800 -0.9394 0.1454 3.1478 0.3715 0.3788 0.1552 1.4892 0.0393 1.1510 0.0707</span> +<span class="r-out co"><span class="r-pr">#></span> 489: 92.1931 -5.8241 -0.0787 2.3796 -0.9394 0.1455 3.1468 0.3715 0.3787 0.1551 1.4895 0.0393 1.1514 0.0706</span> +<span class="r-out co"><span class="r-pr">#></span> 490: 92.1934 -5.8242 -0.0790 2.3793 -0.9393 0.1456 3.1478 0.3715 0.3786 0.1551 1.4898 0.0393 1.1528 0.0706</span> +<span class="r-out co"><span class="r-pr">#></span> 491: 92.1936 -5.8241 -0.0792 2.3788 -0.9392 0.1455 3.1472 0.3715 0.3785 0.1551 1.4900 0.0393 1.1533 0.0706</span> +<span class="r-out co"><span class="r-pr">#></span> 492: 92.1940 -5.8234 -0.0794 2.3783 -0.9391 0.1455 3.1449 0.3714 0.3783 0.1551 1.4903 0.0392 1.1538 0.0705</span> +<span class="r-out co"><span class="r-pr">#></span> 493: 92.1943 -5.8230 -0.0797 2.3779 -0.9390 0.1455 3.1426 0.3714 0.3783 0.1552 1.4907 0.0392 1.1541 0.0705</span> +<span class="r-out co"><span class="r-pr">#></span> 494: 92.1946 -5.8226 -0.0799 2.3774 -0.9390 0.1458 3.1405 0.3713 0.3782 0.1551 1.4911 0.0392 1.1541 0.0706</span> +<span class="r-out co"><span class="r-pr">#></span> 495: 92.1948 -5.8219 -0.0802 2.3770 -0.9391 0.1459 3.1366 0.3712 0.3782 0.1551 1.4916 0.0392 1.1543 0.0706</span> +<span class="r-out co"><span class="r-pr">#></span> 496: 92.1948 -5.8213 -0.0804 2.3766 -0.9392 0.1460 3.1331 0.3711 0.3781 0.1552 1.4920 0.0392 1.1556 0.0705</span> +<span class="r-out co"><span class="r-pr">#></span> 497: 92.1949 -5.8213 -0.0806 2.3762 -0.9393 0.1462 3.1326 0.3711 0.3780 0.1553 1.4923 0.0391 1.1564 0.0705</span> +<span class="r-out co"><span class="r-pr">#></span> 498: 92.1950 -5.8215 -0.0808 2.3758 -0.9394 0.1462 3.1331 0.3710 0.3779 0.1553 1.4926 0.0391 1.1568 0.0705</span> +<span class="r-out co"><span class="r-pr">#></span> 499: 92.1953 -5.8219 -0.0810 2.3754 -0.9395 0.1461 3.1343 0.3709 0.3778 0.1554 1.4929 0.0391 1.1567 0.0705</span> +<span class="r-out co"><span class="r-pr">#></span> 500: 92.1957 -5.8232 -0.0812 2.3751 -0.9395 0.1459 3.1411 0.3709 0.3776 0.1554 1.4931 0.0391 1.1575 0.0705</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-in"><span class="va">f_nlmixr_fomc_sfo_focei_obs_tc</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_tc</span><span class="op">[</span><span class="st">"FOMC-SFO"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"focei"</span>,</span> +<span class="r-in"> error_model <span class="op">=</span> <span class="st">"obs_tc"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="font-weight: bold;">Key:</span> U: Unscaled Parameters; X: Back-transformed parameters; G: Gill difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> F: Forward difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> C: Central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> M: Mixed forward and central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> Unscaled parameters for Omegas=chol(solve(omega));</span> +<span class="r-out co"><span class="r-pr">#></span> Diagonals are transformed, as specified by foceiControl(diagXform=)</span> +<span class="r-out co"><span class="r-pr">#></span> |-----+---------------+-----------+-----------+-----------+-----------|</span> +<span class="r-out co"><span class="r-pr">#></span> | #| Objective Fun | parent_0 | log_k_A1 |f_parent_qlogis | log_alpha |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| log_beta |sigma_low_parent |rsd_high_parent |sigma_low_A1 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................|rsd_high_A1 | o1 | o2 | o3 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| o4 | o5 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 1</span>| 500.20030 | 1.000 | -1.000 | -0.9113 | -0.8944 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.8678 | -0.8916 | -0.8678 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8916 | -0.8767 | -0.8743 | -0.8675 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8704 | -0.8704 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 500.2003 | 93.00 | -5.300 | -0.9400 | -0.1100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.200 | 0.03000 | 1.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03000 | 0.7598 | 0.8758 | 1.214 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.068 | 1.071 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 500.2003</span> | 93.00 | 0.004992 | 0.2809 | 0.8958 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.200 | 0.03000 | 1.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03000 | 0.7598 | 0.8758 | 1.214 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.068 | 1.071 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | G| Gill Diff. | 48.88 | 2.383 | 0.1231 | 0.1986 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1571 | -68.85 | -20.11 | 3.616 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.292 | 0.6250 | 11.41 | -12.48 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -9.903 | -10.91 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 2</span>| 2737.7532 | 0.4556 | -1.027 | -0.9127 | -0.8966 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8471 | -0.1009 | -0.6676 | -0.9080 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8660 | -0.8837 | -1.001 | -0.7285 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7601 | -0.7489 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 2737.7532 | 42.37 | -5.327 | -0.9413 | -0.1122 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.298 | 1.660 | 0.03336 | 1.176 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03038 | 0.7545 | 0.7645 | 1.383 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.185 | 1.201 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 2737.7532</span> | 42.37 | 0.004861 | 0.2806 | 0.8939 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.957 | 1.660 | 0.03336 | 1.176 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03038 | 0.7545 | 0.7645 | 1.383 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.185 | 1.201 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 3</span>| 513.07755 | 0.9456 | -1.003 | -0.9114 | -0.8946 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.7911 | -0.8692 | -0.8718 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8890 | -0.8774 | -0.8871 | -0.8536 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8594 | -0.8582 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 513.07755 | 87.94 | -5.303 | -0.9401 | -0.1102 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.246 | 0.03034 | 1.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03004 | 0.7593 | 0.8646 | 1.231 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.079 | 1.084 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 513.07755</span> | 87.94 | 0.004978 | 0.2809 | 0.8956 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.972 | 1.246 | 0.03034 | 1.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03004 | 0.7593 | 0.8646 | 1.231 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.079 | 1.084 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 4</span>| 499.28604 | 0.9888 | -1.001 | -0.9113 | -0.8945 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.8520 | -0.8870 | -0.8686 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8910 | -0.8769 | -0.8770 | -0.8646 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8682 | -0.8679 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 499.28604 | 91.96 | -5.301 | -0.9400 | -0.1100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.209 | 0.03007 | 1.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03001 | 0.7597 | 0.8735 | 1.218 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.070 | 1.074 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 499.28604</span> | 91.96 | 0.004989 | 0.2809 | 0.8958 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.209 | 0.03007 | 1.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03001 | 0.7597 | 0.8735 | 1.218 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.070 | 1.074 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -111.5 | 2.236 | -0.2057 | 0.1035 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1971 | -66.17 | -21.17 | 4.107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.586 | 1.583 | 8.991 | -11.70 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -9.625 | -10.49 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 5</span>| 497.76004 | 1.001 | -1.001 | -0.9113 | -0.8945 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.8366 | -0.8822 | -0.8695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8906 | -0.8771 | -0.8792 | -0.8619 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8660 | -0.8654 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 497.76004 | 93.05 | -5.301 | -0.9400 | -0.1101 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.219 | 0.03014 | 1.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03001 | 0.7595 | 0.8715 | 1.221 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.072 | 1.076 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 497.76004</span> | 93.05 | 0.004986 | 0.2809 | 0.8958 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.219 | 0.03014 | 1.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03001 | 0.7595 | 0.8715 | 1.221 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.072 | 1.076 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 56.91 | 2.356 | 0.1468 | 0.2109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1761 | -64.61 | -18.67 | 3.291 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.680 | 1.108 | 8.338 | -11.70 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -9.518 | -10.47 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 6</span>| 496.73820 | 0.9899 | -1.002 | -0.9113 | -0.8945 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.8205 | -0.8775 | -0.8703 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8902 | -0.8774 | -0.8813 | -0.8590 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8636 | -0.8628 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 496.7382 | 92.06 | -5.302 | -0.9400 | -0.1101 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.228 | 0.03021 | 1.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03002 | 0.7593 | 0.8696 | 1.225 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.075 | 1.079 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 496.7382</span> | 92.06 | 0.004983 | 0.2809 | 0.8957 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.228 | 0.03021 | 1.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03002 | 0.7593 | 0.8696 | 1.225 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.075 | 1.079 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -94.52 | 2.222 | -0.1721 | 0.1131 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1712 | -62.76 | -19.55 | 3.974 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.718 | 1.304 | 7.360 | -11.47 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -9.402 | -10.21 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 7</span>| 495.33979 | 1.001 | -1.002 | -0.9113 | -0.8946 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.8044 | -0.8726 | -0.8713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8897 | -0.8777 | -0.8834 | -0.8560 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8612 | -0.8602 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 495.33979 | 93.05 | -5.302 | -0.9400 | -0.1102 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.238 | 0.03028 | 1.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03003 | 0.7591 | 0.8679 | 1.228 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.077 | 1.082 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 495.33979</span> | 93.05 | 0.004981 | 0.2809 | 0.8957 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.238 | 0.03028 | 1.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03003 | 0.7591 | 0.8679 | 1.228 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.077 | 1.082 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 56.11 | 2.327 | 0.1520 | 0.2091 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1742 | -61.13 | -17.23 | 3.435 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.620 | 1.132 | 9.399 | -11.44 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -9.328 | -10.19 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 8</span>| 494.31617 | 0.9904 | -1.003 | -0.9113 | -0.8946 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.7881 | -0.8680 | -0.8722 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8893 | -0.8780 | -0.8859 | -0.8530 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8587 | -0.8575 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.31617 | 92.11 | -5.303 | -0.9400 | -0.1102 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.248 | 0.03035 | 1.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03003 | 0.7589 | 0.8657 | 1.232 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.080 | 1.085 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.31617</span> | 92.11 | 0.004977 | 0.2809 | 0.8956 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.248 | 0.03035 | 1.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03003 | 0.7589 | 0.8657 | 1.232 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.080 | 1.085 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -86.81 | 2.198 | -0.1566 | 0.1238 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1638 | -59.37 | -18.02 | 4.057 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.591 | 1.325 | 8.479 | -11.19 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -9.201 | -9.937 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 9</span>| 493.00423 | 1.001 | -1.003 | -0.9113 | -0.8947 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.7718 | -0.8631 | -0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8888 | -0.8783 | -0.8883 | -0.8499 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8562 | -0.8548 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 493.00423 | 93.05 | -5.303 | -0.9400 | -0.1103 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.258 | 0.03043 | 1.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03004 | 0.7586 | 0.8635 | 1.236 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.083 | 1.088 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 493.00423</span> | 93.05 | 0.004974 | 0.2809 | 0.8956 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.258 | 0.03043 | 1.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03004 | 0.7586 | 0.8635 | 1.236 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.083 | 1.088 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 54.84 | 2.286 | 0.1404 | 0.2142 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1628 | -57.96 | -15.94 | 3.372 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.642 | 1.184 | 9.036 | -11.17 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -9.110 | -9.901 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 10</span>| 491.99601 | 0.9908 | -1.004 | -0.9114 | -0.8947 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.7552 | -0.8585 | -0.8742 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8884 | -0.8786 | -0.8910 | -0.8467 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8536 | -0.8520 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 491.99601 | 92.15 | -5.304 | -0.9401 | -0.1103 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.268 | 0.03050 | 1.196 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03005 | 0.7584 | 0.8612 | 1.239 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.085 | 1.091 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 491.99601</span> | 92.15 | 0.004971 | 0.2809 | 0.8956 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.268 | 0.03050 | 1.196 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03005 | 0.7584 | 0.8612 | 1.239 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.085 | 1.091 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -80.67 | 2.171 | -0.1367 | 0.1256 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1610 | -56.13 | -16.61 | 4.047 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.607 | 1.226 | 8.142 | -10.92 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -8.982 | -9.644 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 11</span>| 490.76421 | 1.000 | -1.005 | -0.9113 | -0.8948 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.7388 | -0.8538 | -0.8754 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8879 | -0.8790 | -0.8935 | -0.8435 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8510 | -0.8492 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 490.76421 | 93.04 | -5.305 | -0.9401 | -0.1104 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.277 | 0.03057 | 1.195 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03006 | 0.7581 | 0.8590 | 1.243 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.088 | 1.094 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 490.76421</span> | 93.04 | 0.004968 | 0.2809 | 0.8955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.277 | 0.03057 | 1.195 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03006 | 0.7581 | 0.8590 | 1.243 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.088 | 1.094 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 54.34 | 2.256 | 0.1715 | 0.2224 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1653 | -54.87 | -14.72 | 3.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.777 | 1.023 | 8.651 | -10.90 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -8.887 | -9.594 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 12</span>| 489.76286 | 0.9913 | -1.005 | -0.9114 | -0.8948 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.7220 | -0.8492 | -0.8764 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8873 | -0.8793 | -0.8962 | -0.8402 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8483 | -0.8462 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 489.76286 | 92.19 | -5.305 | -0.9401 | -0.1104 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.287 | 0.03063 | 1.195 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03006 | 0.7579 | 0.8566 | 1.247 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.091 | 1.097 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 489.76286</span> | 92.19 | 0.004965 | 0.2809 | 0.8955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.287 | 0.03063 | 1.195 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03006 | 0.7579 | 0.8566 | 1.247 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.091 | 1.097 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -73.18 | 2.145 | -0.1190 | 0.1261 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1580 | -53.08 | -15.27 | 4.015 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.639 | 1.110 | 7.813 | -10.65 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -8.743 | -9.338 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 13</span>| 488.61493 | 1.000 | -1.006 | -0.9114 | -0.8949 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.7053 | -0.8446 | -0.8776 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8867 | -0.8796 | -0.8989 | -0.8368 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8455 | -0.8433 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 488.61493 | 93.04 | -5.306 | -0.9401 | -0.1105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.297 | 0.03070 | 1.194 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03007 | 0.7577 | 0.8543 | 1.252 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.094 | 1.100 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 488.61493</span> | 93.04 | 0.004961 | 0.2809 | 0.8954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.297 | 0.03070 | 1.194 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03007 | 0.7577 | 0.8543 | 1.252 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.094 | 1.100 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 54.41 | 2.230 | 0.1889 | 0.2376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1637 | -52.01 | -13.54 | 3.223 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.937 | 0.8847 | 10.07 | -10.59 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -8.650 | -9.282 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 14</span>| 487.61806 | 0.9919 | -1.007 | -0.9114 | -0.8949 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.6884 | -0.8402 | -0.8788 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8861 | -0.8798 | -0.9022 | -0.8333 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8427 | -0.8402 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 487.61806 | 92.24 | -5.307 | -0.9401 | -0.1105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.308 | 0.03077 | 1.193 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03008 | 0.7575 | 0.8514 | 1.256 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.097 | 1.103 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 487.61806</span> | 92.24 | 0.004958 | 0.2809 | 0.8953 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.308 | 0.03077 | 1.193 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03008 | 0.7575 | 0.8514 | 1.256 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.097 | 1.103 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -64.97 | 2.116 | -0.09941 | 0.1372 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1475 | -50.35 | -14.02 | 3.916 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.790 | 0.8979 | 9.163 | -10.32 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -8.505 | -9.022 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 15</span>| 486.55968 | 1.001 | -1.008 | -0.9114 | -0.8950 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.6717 | -0.8358 | -0.8800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8854 | -0.8801 | -0.9058 | -0.8297 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8398 | -0.8372 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 486.55968 | 93.05 | -5.308 | -0.9401 | -0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.318 | 0.03084 | 1.193 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03009 | 0.7573 | 0.8482 | 1.260 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.100 | 1.107 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 486.55968</span> | 93.05 | 0.004954 | 0.2809 | 0.8953 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.318 | 0.03084 | 1.193 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03009 | 0.7573 | 0.8482 | 1.260 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.100 | 1.107 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 55.08 | 2.188 | 0.1916 | 0.2341 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1660 | -48.95 | -12.27 | 3.347 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.726 | 0.9589 | 6.446 | -10.30 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -8.390 | -8.950 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 16</span>| 485.60262 | 0.9920 | -1.008 | -0.9115 | -0.8951 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.6547 | -0.8316 | -0.8813 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8847 | -0.8804 | -0.9083 | -0.8260 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8367 | -0.8340 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 485.60262 | 92.26 | -5.308 | -0.9402 | -0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.328 | 0.03090 | 1.192 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03010 | 0.7571 | 0.8460 | 1.265 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.104 | 1.110 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 485.60262</span> | 92.26 | 0.004950 | 0.2809 | 0.8952 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.328 | 0.03090 | 1.192 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03010 | 0.7571 | 0.8460 | 1.265 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.104 | 1.110 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -62.47 | 2.078 | -0.09882 | 0.1294 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1587 | -47.42 | -12.81 | 3.926 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.683 | 0.9415 | 5.611 | -10.02 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -8.237 | -8.679 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 17</span>| 484.58535 | 1.000 | -1.009 | -0.9115 | -0.8952 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.6375 | -0.8274 | -0.8829 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8840 | -0.8807 | -0.9099 | -0.8222 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8336 | -0.8307 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 484.58535 | 93.02 | -5.309 | -0.9402 | -0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.338 | 0.03096 | 1.191 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03011 | 0.7568 | 0.8446 | 1.269 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.114 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 484.58535</span> | 93.02 | 0.004946 | 0.2809 | 0.8952 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.338 | 0.03096 | 1.191 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03011 | 0.7568 | 0.8446 | 1.269 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.114 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 50.15 | 2.155 | 0.1960 | 0.2225 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1509 | -46.14 | -11.19 | 3.405 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.652 | 1.035 | 7.536 | -9.951 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -8.121 | -8.609 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 18</span>| 483.66860 | 0.9923 | -1.010 | -0.9115 | -0.8952 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.6203 | -0.8235 | -0.8844 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8833 | -0.8810 | -0.9123 | -0.8182 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8303 | -0.8273 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 483.6686 | 92.29 | -5.310 | -0.9402 | -0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.348 | 0.03102 | 1.190 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03012 | 0.7565 | 0.8425 | 1.274 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.110 | 1.117 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 483.6686</span> | 92.29 | 0.004942 | 0.2809 | 0.8951 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.348 | 0.03102 | 1.190 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03012 | 0.7565 | 0.8425 | 1.274 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.110 | 1.117 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -57.62 | 2.059 | -0.07549 | 0.1395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1501 | -44.74 | -11.66 | 3.913 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.664 | 0.8845 | 6.781 | -9.703 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -7.961 | -8.325 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 19</span>| 482.71012 | 1.000 | -1.011 | -0.9115 | -0.8953 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.6032 | -0.8198 | -0.8861 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8825 | -0.8814 | -0.9153 | -0.8141 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8270 | -0.8239 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 482.71012 | 93.02 | -5.311 | -0.9402 | -0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.359 | 0.03108 | 1.189 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03014 | 0.7563 | 0.8399 | 1.279 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.114 | 1.121 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 482.71012</span> | 93.02 | 0.004937 | 0.2809 | 0.8950 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.359 | 0.03108 | 1.189 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03014 | 0.7563 | 0.8399 | 1.279 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.114 | 1.121 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 48.98 | 2.122 | 0.2043 | 0.2315 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1449 | -43.47 | -10.15 | 3.365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.703 | 0.9582 | 7.160 | -9.600 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -7.838 | -8.245 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 20</span>| 481.83107 | 0.9926 | -1.012 | -0.9116 | -0.8954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.5860 | -0.8164 | -0.8879 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8817 | -0.8818 | -0.9184 | -0.8098 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8235 | -0.8203 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 481.83107 | 92.31 | -5.312 | -0.9403 | -0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.369 | 0.03113 | 1.188 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03015 | 0.7560 | 0.8372 | 1.284 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.118 | 1.125 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 481.83107</span> | 92.31 | 0.004932 | 0.2808 | 0.8949 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.369 | 0.03113 | 1.188 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03015 | 0.7560 | 0.8372 | 1.284 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.118 | 1.125 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -54.27 | 2.027 | -0.06740 | 0.1414 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1465 | -41.84 | -10.48 | 3.798 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.730 | 0.8044 | 6.401 | -9.335 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -7.662 | -7.960 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 21</span>| 480.92878 | 1.000 | -1.013 | -0.9117 | -0.8955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.5689 | -0.8133 | -0.8899 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8807 | -0.8821 | -0.9215 | -0.8053 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8199 | -0.8166 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.92878 | 93.01 | -5.313 | -0.9403 | -0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.379 | 0.03117 | 1.187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03016 | 0.7557 | 0.8345 | 1.290 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.122 | 1.129 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.92878</span> | 93.01 | 0.004927 | 0.2808 | 0.8948 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.379 | 0.03117 | 1.187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03016 | 0.7557 | 0.8345 | 1.290 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.122 | 1.129 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 47.18 | 2.077 | 0.1996 | 0.2200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1318 | -41.07 | -9.197 | 3.259 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.748 | 0.9101 | 6.743 | -9.229 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -7.511 | -7.855 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 22</span>| 480.07574 | 0.9930 | -1.014 | -0.9117 | -0.8956 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8455 | -0.5517 | -0.8106 | -0.8919 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8795 | -0.8825 | -0.9247 | -0.8007 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8161 | -0.8129 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.07574 | 92.35 | -5.314 | -0.9404 | -0.1112 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.390 | 0.03121 | 1.186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03018 | 0.7555 | 0.8317 | 1.295 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.126 | 1.133 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.07574</span> | 92.35 | 0.004921 | 0.2808 | 0.8947 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.973 | 1.390 | 0.03121 | 1.186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03018 | 0.7555 | 0.8317 | 1.295 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.126 | 1.133 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -48.22 | 1.995 | -0.04658 | 0.1415 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1316 | -39.56 | -9.522 | 3.639 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.878 | 0.6154 | 4.556 | -8.937 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -7.320 | -7.563 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 23</span>| 479.25211 | 1.000 | -1.015 | -0.9118 | -0.8957 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.5343 | -0.8082 | -0.8940 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8781 | -0.8826 | -0.9261 | -0.7958 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8122 | -0.8090 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.25211 | 93.02 | -5.315 | -0.9405 | -0.1113 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.400 | 0.03125 | 1.184 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03020 | 0.7553 | 0.8305 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.130 | 1.137 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.25211</span> | 93.02 | 0.004915 | 0.2808 | 0.8946 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.400 | 0.03125 | 1.184 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03020 | 0.7553 | 0.8305 | 1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.130 | 1.137 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 48.39 | 2.048 | 0.2189 | 0.2175 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1393 | -38.80 | -8.286 | 3.169 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.757 | 0.9021 | 6.456 | -8.802 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -7.165 | -7.452 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 24</span>| 478.42395 | 0.9935 | -1.017 | -0.9119 | -0.8959 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.5169 | -0.8064 | -0.8963 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8766 | -0.8829 | -0.9277 | -0.7908 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8081 | -0.8051 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.42395 | 92.40 | -5.317 | -0.9406 | -0.1115 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.411 | 0.03128 | 1.183 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03022 | 0.7552 | 0.8290 | 1.307 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.134 | 1.141 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.42395</span> | 92.40 | 0.004909 | 0.2808 | 0.8945 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.411 | 0.03128 | 1.183 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03022 | 0.7552 | 0.8290 | 1.307 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.134 | 1.141 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -41.65 | 1.977 | -0.02866 | 0.1453 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1180 | -37.67 | -8.677 | 3.579 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.774 | 0.6894 | 5.855 | -8.506 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -6.962 | -7.153 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 25</span>| 477.65816 | 1.000 | -1.018 | -0.9120 | -0.8960 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.4997 | -0.8051 | -0.8988 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8750 | -0.8832 | -0.9313 | -0.7859 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8042 | -0.8013 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 477.65816 | 93.02 | -5.318 | -0.9406 | -0.1116 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.421 | 0.03130 | 1.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03025 | 0.7549 | 0.8259 | 1.313 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.138 | 1.145 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 477.65816</span> | 93.02 | 0.004901 | 0.2808 | 0.8944 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.421 | 0.03130 | 1.181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03025 | 0.7549 | 0.8259 | 1.313 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.138 | 1.145 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 47.50 | 2.013 | 0.2278 | 0.2145 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1415 | -36.68 | -7.460 | 3.039 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.807 | 0.8669 | 6.124 | -8.373 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -6.814 | -7.074 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 26</span>| 476.87668 | 0.9936 | -1.020 | -0.9121 | -0.8962 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.4825 | -0.8047 | -0.9014 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8732 | -0.8836 | -0.9351 | -0.7808 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8001 | -0.7975 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.87668 | 92.41 | -5.320 | -0.9408 | -0.1117 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.431 | 0.03130 | 1.180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03028 | 0.7546 | 0.8226 | 1.319 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.143 | 1.149 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.87668</span> | 92.41 | 0.004893 | 0.2807 | 0.8943 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.431 | 0.03130 | 1.180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03028 | 0.7546 | 0.8226 | 1.319 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.143 | 1.149 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -40.64 | 1.935 | -0.02164 | 0.1511 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1127 | -35.59 | -7.858 | 3.450 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.805 | 0.6731 | 3.945 | -8.048 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -6.589 | -6.756 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 27</span>| 476.16299 | 1.000 | -1.022 | -0.9123 | -0.8963 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.4651 | -0.8047 | -0.9041 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8711 | -0.8840 | -0.9355 | -0.7757 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7959 | -0.7936 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.16299 | 93.01 | -5.322 | -0.9409 | -0.1119 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.442 | 0.03130 | 1.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03031 | 0.7543 | 0.8222 | 1.326 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.147 | 1.153 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.16299</span> | 93.01 | 0.004885 | 0.2807 | 0.8941 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.442 | 0.03130 | 1.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03031 | 0.7543 | 0.8222 | 1.326 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.147 | 1.153 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 44.38 | 1.982 | 0.2331 | 0.2213 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1467 | -34.64 | -6.709 | 2.894 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.888 | 0.7760 | 4.358 | -7.901 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -6.419 | -6.620 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 28</span>| 475.47434 | 0.9938 | -1.024 | -0.9125 | -0.8966 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.4477 | -0.8058 | -0.9069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8685 | -0.8844 | -0.9328 | -0.7706 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7919 | -0.7898 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.47434 | 92.43 | -5.324 | -0.9411 | -0.1122 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.452 | 0.03129 | 1.177 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03035 | 0.7540 | 0.8246 | 1.332 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.151 | 1.157 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.47434</span> | 92.43 | 0.004875 | 0.2807 | 0.8939 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.452 | 0.03129 | 1.177 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03035 | 0.7540 | 0.8246 | 1.332 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.151 | 1.157 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -38.01 | 1.932 | -0.02542 | 0.1483 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1147 | -33.71 | -7.114 | 3.216 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.879 | 0.6267 | 4.067 | -7.573 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -6.213 | -6.338 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 29</span>| 474.82575 | 0.9998 | -1.026 | -0.9126 | -0.8968 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.4303 | -0.8075 | -0.9096 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8656 | -0.8846 | -0.9310 | -0.7657 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7878 | -0.7862 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.82575 | 92.98 | -5.326 | -0.9413 | -0.1124 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.462 | 0.03126 | 1.175 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03039 | 0.7538 | 0.8261 | 1.338 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.156 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.82575</span> | 92.98 | 0.004864 | 0.2806 | 0.8937 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.462 | 0.03126 | 1.175 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03039 | 0.7538 | 0.8261 | 1.338 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.156 | 1.161 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 40.83 | 1.980 | 0.2123 | 0.2125 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1324 | -32.65 | -6.032 | 2.979 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.922 | 0.7692 | 4.596 | -7.426 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -6.058 | -6.217 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 30</span>| 474.18202 | 0.9939 | -1.028 | -0.9128 | -0.8971 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.4131 | -0.8106 | -0.9130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8620 | -0.8851 | -0.9307 | -0.7608 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7838 | -0.7828 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.18202 | 92.44 | -5.328 | -0.9414 | -0.1127 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.473 | 0.03121 | 1.173 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03044 | 0.7535 | 0.8264 | 1.344 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.160 | 1.165 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.18202</span> | 92.44 | 0.004852 | 0.2806 | 0.8935 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.473 | 0.03121 | 1.173 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03044 | 0.7535 | 0.8264 | 1.344 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.160 | 1.165 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -37.33 | 1.920 | -0.03157 | 0.1462 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1145 | -31.92 | -6.433 | 3.018 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.919 | 0.6114 | 5.640 | -7.155 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -5.876 | -5.958 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 31</span>| 473.55376 | 0.9995 | -1.031 | -0.9130 | -0.8973 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8454 | -0.3971 | -0.8148 | -0.9162 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8581 | -0.8855 | -0.9368 | -0.7563 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7800 | -0.7797 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.55376 | 92.95 | -5.331 | -0.9416 | -0.1129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.482 | 0.03115 | 1.171 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03050 | 0.7531 | 0.8211 | 1.349 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.164 | 1.168 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.55376</span> | 92.95 | 0.004838 | 0.2806 | 0.8932 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.974 | 1.482 | 0.03115 | 1.171 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03050 | 0.7531 | 0.8211 | 1.349 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.164 | 1.168 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 32</span>| 472.90182 | 0.9995 | -1.035 | -0.9132 | -0.8977 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8453 | -0.3799 | -0.8225 | -0.9204 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8527 | -0.8861 | -0.9447 | -0.7510 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7757 | -0.7763 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 472.90182 | 92.96 | -5.335 | -0.9418 | -0.1133 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.493 | 0.03104 | 1.168 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03058 | 0.7527 | 0.8141 | 1.356 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.169 | 1.172 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 472.90182</span> | 92.96 | 0.004819 | 0.2805 | 0.8929 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.975 | 1.493 | 0.03104 | 1.168 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03058 | 0.7527 | 0.8141 | 1.356 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.169 | 1.172 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 33</span>| 469.90339 | 0.9997 | -1.054 | -0.9142 | -0.8996 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8452 | -0.2944 | -0.8611 | -0.9412 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8255 | -0.8889 | -0.9843 | -0.7249 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7539 | -0.7597 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 469.90339 | 92.98 | -5.354 | -0.9427 | -0.1152 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.300 | 1.544 | 0.03046 | 1.156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03099 | 0.7505 | 0.7794 | 1.387 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.192 | 1.190 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 469.90339</span> | 92.98 | 0.004727 | 0.2803 | 0.8912 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.976 | 1.544 | 0.03046 | 1.156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03099 | 0.7505 | 0.7794 | 1.387 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.192 | 1.190 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 34</span>| 461.71523 | 1.001 | -1.134 | -0.9184 | -0.9072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8447 | 0.05742 | -1.020 | -1.027 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7136 | -0.9005 | -1.147 | -0.6175 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6642 | -0.6913 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 461.71523 | 93.05 | -5.434 | -0.9467 | -0.1228 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.301 | 1.755 | 0.02808 | 1.105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03267 | 0.7417 | 0.6368 | 1.518 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.288 | 1.263 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 461.71523</span> | 93.05 | 0.004366 | 0.2795 | 0.8844 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.981 | 1.755 | 0.02808 | 1.105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03267 | 0.7417 | 0.6368 | 1.518 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.288 | 1.263 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 11.20 | 1.045 | 1.020 | 0.3495 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7923 | -15.00 | -0.3969 | -1.315 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -3.031 | 0.2676 | -6.780 | -1.078 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.09081 | -1.463 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 35</span>| 459.94653 | 1.009 | -1.206 | -0.9768 | -0.9283 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8884 | 0.4547 | -1.238 | -0.9419 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5030 | -0.9080 | -0.7892 | -0.6450 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7313 | -0.6959 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 459.94653 | 93.85 | -5.506 | -1.002 | -0.1439 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.257 | 1.993 | 0.02480 | 1.155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03583 | 0.7361 | 0.9504 | 1.484 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.216 | 1.258 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 459.94653</span> | 93.85 | 0.004064 | 0.2686 | 0.8660 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.554 | 1.993 | 0.02480 | 1.155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03583 | 0.7361 | 0.9504 | 1.484 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.216 | 1.258 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 117.0 | 1.389 | -1.721 | -0.1200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.004314 | -5.763 | 2.093 | 3.426 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.378 | 2.600 | 15.14 | -1.236 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -4.018 | -1.529 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 36</span>| 458.11528 | 1.003 | -1.307 | -0.9477 | -0.9422 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9430 | 0.6906 | -1.630 | -0.8850 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1864 | -1.043 | -0.8947 | -0.8359 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7822 | -0.7759 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 458.11528 | 93.30 | -5.607 | -0.9742 | -0.1578 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.202 | 2.135 | 0.01893 | 1.190 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.04058 | 0.6334 | 0.8579 | 1.253 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.162 | 1.172 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 458.11528</span> | 93.30 | 0.003671 | 0.2740 | 0.8540 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.046 | 2.135 | 0.01893 | 1.190 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.04058 | 0.6334 | 0.8579 | 1.253 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.162 | 1.172 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.502 | 0.8367 | -0.1865 | -0.1361 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6555 | -2.945 | 1.425 | 8.523 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6882 | -2.700 | 7.982 | -9.961 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -6.514 | -5.474 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 37</span>| 454.42202 | 1.008 | -1.411 | -0.9501 | -0.9563 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9900 | 0.8215 | -2.099 | -1.032 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1520 | -1.049 | -0.9274 | -0.7533 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7158 | -0.7241 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 454.42202 | 93.74 | -5.711 | -0.9765 | -0.1719 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.155 | 2.214 | 0.01188 | 1.102 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.04565 | 0.6287 | 0.8293 | 1.353 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.233 | 1.228 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 454.42202</span> | 93.74 | 0.003311 | 0.2736 | 0.8421 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.631 | 2.214 | 0.01188 | 1.102 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.04565 | 0.6287 | 0.8293 | 1.353 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.233 | 1.228 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 38</span>| 451.48622 | 1.000 | -1.659 | -0.9551 | -0.9914 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.111 | 1.029 | -2.892 | -1.353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9897 | -1.076 | -0.9627 | -0.6147 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5957 | -0.6379 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 451.48622 | 93.01 | -5.959 | -0.9812 | -0.2070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.035 | 2.338 | 5.960e-07 | 0.9088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.05822 | 0.6083 | 0.7984 | 1.521 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.361 | 1.320 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 451.48622</span> | 93.01 | 0.002583 | 0.2727 | 0.8130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 7.651 | 2.338 | 5.960e-07 | 0.9088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.05822 | 0.6083 | 0.7984 | 1.521 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.361 | 1.320 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -68.34 | 0.03355 | 0.09905 | -1.306 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -5.058 | -1.204 | -0.09883 | -1.076 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.726 | -4.145 | 7.646 | -0.5743 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.003 | 2.613 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 39</span>| 453.25472 | 1.003 | -2.027 | -1.069 | -0.8933 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6960 | 1.084 | -2.892 | -1.695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.689 | -0.4882 | -1.206 | -0.2814 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7545 | -0.8496 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 453.25472 | 93.31 | -6.327 | -1.089 | -0.1089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.449 | 2.371 | 5.960e-07 | 0.7037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08370 | 1.055 | 0.5857 | 1.926 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.191 | 1.093 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 453.25472</span> | 93.31 | 0.001787 | 0.2519 | 0.8968 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 11.58 | 2.371 | 5.960e-07 | 0.7037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08370 | 1.055 | 0.5857 | 1.926 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.191 | 1.093 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 40</span>| 449.59369 | 1.000 | -1.818 | -1.010 | -0.9508 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9364 | 1.052 | -2.892 | -1.498 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.730 | -0.8175 | -1.073 | -0.4671 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6691 | -0.7270 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 449.59369 | 93.04 | -6.118 | -1.033 | -0.1664 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.209 | 2.352 | 5.960e-07 | 0.8216 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06933 | 0.8048 | 0.7021 | 1.700 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.282 | 1.225 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 449.59369</span> | 93.04 | 0.002202 | 0.2625 | 0.8467 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.106 | 2.352 | 5.960e-07 | 0.8216 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06933 | 0.8048 | 0.7021 | 1.700 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.282 | 1.225 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -128.1 | 0.1096 | -3.510 | -0.1773 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1823 | -1.358 | -0.002263 | 1.313 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.294 | 5.530 | 5.100 | 4.831 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.292 | -3.851 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 41</span>| 472.13387 | 1.020 | -1.985 | -0.7592 | -0.7822 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2976 | 1.062 | -2.892 | -1.866 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.141 | -0.7519 | -1.136 | -0.6405 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7706 | -0.2153 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 472.13387 | 94.83 | -6.285 | -0.7970 | 0.002176 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.848 | 2.358 | 5.960e-07 | 0.6009 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.09049 | 0.8547 | 0.6467 | 1.490 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.174 | 1.773 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 472.13387</span> | 94.83 | 0.001864 | 0.3107 | 1.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 17.25 | 2.358 | 5.960e-07 | 0.6009 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.09049 | 0.8547 | 0.6467 | 1.490 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.174 | 1.773 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 42</span>| 454.13083 | 1.030 | -1.841 | -0.9756 | -0.9280 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8501 | 1.054 | -2.892 | -1.548 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.921 | -0.8098 | -1.082 | -0.4916 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6825 | -0.6571 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 454.13083 | 95.82 | -6.141 | -1.000 | -0.1436 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.295 | 2.353 | 5.960e-07 | 0.7917 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.07219 | 0.8106 | 0.6936 | 1.671 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.268 | 1.299 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 454.13083</span> | 95.82 | 0.002153 | 0.2688 | 0.8663 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.927 | 2.353 | 5.960e-07 | 0.7917 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.07219 | 0.8106 | 0.6936 | 1.671 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.268 | 1.299 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 43</span>| 454.81886 | 1.032 | -1.823 | -1.002 | -0.9459 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9179 | 1.053 | -2.892 | -1.509 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.771 | -0.8169 | -1.076 | -0.4733 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6717 | -0.7113 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 454.81886 | 95.94 | -6.123 | -1.025 | -0.1614 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.227 | 2.352 | 5.960e-07 | 0.8150 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06994 | 0.8052 | 0.6994 | 1.693 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.280 | 1.241 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 454.81886</span> | 95.94 | 0.002192 | 0.2640 | 0.8509 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.277 | 2.352 | 5.960e-07 | 0.8150 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06994 | 0.8052 | 0.6994 | 1.693 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.280 | 1.241 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 44</span>| 449.57011 | 1.014 | -1.818 | -1.010 | -0.9508 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9364 | 1.053 | -2.892 | -1.499 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.730 | -0.8181 | -1.073 | -0.4676 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6690 | -0.7267 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 449.57011 | 94.27 | -6.118 | -1.033 | -0.1664 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.209 | 2.352 | 5.995e-07 | 0.8215 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06933 | 0.8044 | 0.7016 | 1.700 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.283 | 1.225 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 449.57011</span> | 94.27 | 0.002202 | 0.2626 | 0.8467 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.106 | 2.352 | 5.995e-07 | 0.8215 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06933 | 0.8044 | 0.7016 | 1.700 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.283 | 1.225 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 126.9 | 0.1582 | -2.201 | 0.05331 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4695 | -0.6265 | 0.01503 | 0.4241 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.337 | 5.854 | 6.688 | 4.536 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.410 | -4.016 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 45</span>| 449.14922 | 1.007 | -1.818 | -1.010 | -0.9508 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9364 | 1.053 | -2.892 | -1.499 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.730 | -0.8183 | -1.074 | -0.4678 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6689 | -0.7265 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 449.14922 | 93.66 | -6.118 | -1.033 | -0.1664 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.209 | 2.352 | 5.960e-07 | 0.8215 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06933 | 0.8042 | 0.7014 | 1.699 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.283 | 1.225 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 449.14922</span> | 93.66 | 0.002202 | 0.2626 | 0.8467 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.106 | 2.352 | 5.960e-07 | 0.8215 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06933 | 0.8042 | 0.7014 | 1.699 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.283 | 1.225 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.4066 | 0.1367 | -2.828 | -0.06013 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1445 | -0.8286 | 0.01677 | 0.9213 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.224 | 4.943 | 4.017 | 5.223 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.311 | -3.922 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 46</span>| 449.08136 | 1.007 | -1.818 | -1.008 | -0.9507 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9365 | 1.053 | -2.892 | -1.499 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.731 | -0.8217 | -1.076 | -0.4714 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6680 | -0.7238 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 449.08136 | 93.68 | -6.118 | -1.031 | -0.1663 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.209 | 2.353 | 5.960e-07 | 0.8212 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06934 | 0.8016 | 0.6990 | 1.695 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.284 | 1.228 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 449.08136</span> | 93.68 | 0.002202 | 0.2629 | 0.8468 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.105 | 2.353 | 5.960e-07 | 0.8212 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06934 | 0.8016 | 0.6990 | 1.695 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.284 | 1.228 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 47</span>| 448.89872 | 1.008 | -1.819 | -1.002 | -0.9506 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9368 | 1.055 | -2.892 | -1.501 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.734 | -0.8317 | -1.084 | -0.4820 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6654 | -0.7159 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 448.89872 | 93.76 | -6.119 | -1.025 | -0.1662 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.209 | 2.354 | 5.960e-07 | 0.8200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06938 | 0.7940 | 0.6918 | 1.682 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.286 | 1.237 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 448.89872</span> | 93.76 | 0.002202 | 0.2640 | 0.8469 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.102 | 2.354 | 5.960e-07 | 0.8200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06938 | 0.7940 | 0.6918 | 1.682 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.286 | 1.237 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 48</span>| 448.46351 | 1.011 | -1.820 | -0.9792 | -0.9501 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9380 | 1.062 | -2.892 | -1.509 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.744 | -0.8718 | -1.117 | -0.5244 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6547 | -0.6840 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 448.46351 | 94.07 | -6.120 | -1.004 | -0.1657 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.207 | 2.358 | 5.960e-07 | 0.8155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06953 | 0.7635 | 0.6633 | 1.631 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.298 | 1.271 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 448.46351</span> | 94.07 | 0.002199 | 0.2682 | 0.8473 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.092 | 2.358 | 5.960e-07 | 0.8155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06953 | 0.7635 | 0.6633 | 1.631 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.298 | 1.271 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 75.37 | 0.2597 | -0.1569 | 0.03608 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3501 | -0.3601 | -0.01324 | 0.5025 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.327 | 4.308 | 0.9122 | 2.456 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5631 | -1.887 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 49</span>| 448.12149 | 1.008 | -1.833 | -0.9950 | -0.9378 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8937 | 1.062 | -2.892 | -1.543 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.827 | -0.8899 | -1.115 | -0.5324 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6574 | -0.6703 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 448.12149 | 93.73 | -6.133 | -1.019 | -0.1534 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.252 | 2.358 | 5.960e-07 | 0.7948 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.07077 | 0.7498 | 0.6653 | 1.621 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.295 | 1.285 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 448.12149</span> | 93.73 | 0.002169 | 0.2653 | 0.8578 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.504 | 2.358 | 5.960e-07 | 0.7948 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.07077 | 0.7498 | 0.6653 | 1.621 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.295 | 1.285 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 13.78 | 0.2222 | -1.381 | 0.2569 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.259 | -0.5740 | -0.02850 | 0.1620 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.241 | 3.503 | 0.9893 | 2.205 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7124 | -1.054 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 50</span>| 447.94443 | 1.007 | -1.844 | -0.9902 | -0.9390 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9059 | 1.062 | -2.881 | -1.561 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.911 | -0.9357 | -1.119 | -0.5167 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6474 | -0.7008 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 447.94443 | 93.62 | -6.144 | -1.014 | -0.1546 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.239 | 2.358 | 0.0001615 | 0.7838 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.07204 | 0.7150 | 0.6617 | 1.640 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.306 | 1.253 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 447.94443</span> | 93.62 | 0.002146 | 0.2662 | 0.8567 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.388 | 2.358 | 0.0001615 | 0.7838 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.07204 | 0.7150 | 0.6617 | 1.640 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.306 | 1.253 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.879 | 0.2071 | -1.215 | 0.2527 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8228 | -0.5096 | -0.06036 | 0.4983 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.183 | 1.766 | 2.266 | 2.617 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3179 | -2.389 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 51</span>| 447.77390 | 1.007 | -1.858 | -1.003 | -0.9470 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9285 | 1.056 | -2.855 | -1.583 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.006 | -0.9406 | -1.128 | -0.5198 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6539 | -0.6964 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 447.7739 | 93.69 | -6.158 | -1.026 | -0.1626 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.217 | 2.354 | 0.0005494 | 0.7710 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.07347 | 0.7113 | 0.6533 | 1.636 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.299 | 1.257 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 447.7739</span> | 93.69 | 0.002117 | 0.2639 | 0.8500 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.179 | 2.354 | 0.0005494 | 0.7710 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.07347 | 0.7113 | 0.6533 | 1.636 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.299 | 1.257 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 52</span>| 447.56301 | 1.006 | -1.897 | -1.041 | -0.9708 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9958 | 1.039 | -2.777 | -1.647 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.291 | -0.9540 | -1.156 | -0.5273 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6737 | -0.6848 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 447.56301 | 93.51 | -6.197 | -1.061 | -0.1864 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.150 | 2.344 | 0.001717 | 0.7326 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.07774 | 0.7011 | 0.6293 | 1.627 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.278 | 1.270 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 447.56301</span> | 93.51 | 0.002035 | 0.2570 | 0.8300 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.581 | 2.344 | 0.001717 | 0.7326 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.07774 | 0.7011 | 0.6293 | 1.627 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.278 | 1.270 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -30.60 | 0.2182 | -4.075 | -0.4855 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.237 | -0.6626 | -0.1062 | 0.6612 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6049 | 1.074 | 1.318 | 2.279 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.614 | -1.745 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 53</span>| 447.16930 | 1.007 | -1.971 | -0.9627 | -0.9652 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9709 | 1.044 | -2.781 | -1.732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.691 | -0.9472 | -1.156 | -0.5162 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6828 | -0.6632 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 447.1693 | 93.67 | -6.271 | -0.9883 | -0.1807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.174 | 2.347 | 0.001652 | 0.6812 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08374 | 0.7063 | 0.6288 | 1.641 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.268 | 1.293 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 447.1693</span> | 93.67 | 0.001890 | 0.2713 | 0.8346 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.798 | 2.347 | 0.001652 | 0.6812 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08374 | 0.7063 | 0.6288 | 1.641 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.268 | 1.293 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.693 | 0.1048 | 0.8560 | -0.3278 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6115 | -0.5188 | -0.09596 | 0.9789 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.02585 | 1.094 | 1.548 | 2.318 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.079 | -0.9259 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 54</span>| 447.68852 | 1.013 | -2.042 | -1.008 | -0.9421 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9288 | 1.034 | -2.709 | -1.852 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.037 | -0.9368 | -1.153 | -0.6162 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5399 | -0.6984 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 447.68852 | 94.21 | -6.342 | -1.031 | -0.1577 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.217 | 2.341 | 0.002735 | 0.6094 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08893 | 0.7142 | 0.6313 | 1.519 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.420 | 1.255 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 447.68852</span> | 94.21 | 0.001761 | 0.2629 | 0.8541 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.176 | 2.341 | 0.002735 | 0.6094 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08893 | 0.7142 | 0.6313 | 1.519 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.420 | 1.255 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 55</span>| 447.15405 | 1.011 | -1.991 | -0.9760 | -0.9584 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9586 | 1.042 | -2.761 | -1.767 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.789 | -0.9450 | -1.157 | -0.5460 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6410 | -0.6726 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 447.15405 | 94.04 | -6.291 | -1.001 | -0.1740 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.187 | 2.346 | 0.001959 | 0.6605 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08521 | 0.7080 | 0.6287 | 1.605 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.312 | 1.283 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 447.15405</span> | 94.04 | 0.001852 | 0.2688 | 0.8403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.906 | 2.346 | 0.001959 | 0.6605 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08521 | 0.7080 | 0.6287 | 1.605 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.312 | 1.283 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 53.59 | 0.07914 | 0.2662 | -0.1234 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1097 | -0.6518 | -0.06086 | 0.6193 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.05679 | 1.445 | 0.6511 | 1.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1794 | -1.326 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 56</span>| 447.09915 | 1.005 | -2.002 | -0.9768 | -0.9545 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9567 | 1.042 | -2.752 | -1.789 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.838 | -0.9392 | -1.155 | -0.5617 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6261 | -0.6787 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 447.09915 | 93.47 | -6.302 | -1.002 | -0.1701 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.189 | 2.346 | 0.002096 | 0.6471 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08594 | 0.7123 | 0.6298 | 1.586 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.328 | 1.276 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 447.09915</span> | 93.47 | 0.001833 | 0.2686 | 0.8436 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 8.923 | 2.346 | 0.002096 | 0.6471 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08594 | 0.7123 | 0.6298 | 1.586 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.328 | 1.276 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -33.97 | 0.05091 | -0.1219 | -0.09607 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3249 | -0.8735 | -0.1278 | 0.5888 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06635 | 1.636 | -1.923 | 0.5172 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.5270 | -1.419 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 57</span>| 447.01951 | 1.007 | -2.009 | -0.9874 | -0.9450 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9329 | 1.053 | -2.780 | -1.808 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.841 | -0.9693 | -1.155 | -0.5556 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6514 | -0.6721 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 447.01951 | 93.64 | -6.309 | -1.012 | -0.1606 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.212 | 2.352 | 0.001680 | 0.6361 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08598 | 0.6895 | 0.6300 | 1.593 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.301 | 1.283 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 447.01951</span> | 93.64 | 0.001820 | 0.2667 | 0.8517 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.138 | 2.352 | 0.001680 | 0.6361 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08598 | 0.6895 | 0.6300 | 1.593 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.301 | 1.283 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -6.500 | 0.04518 | -0.6412 | 0.1616 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3106 | -0.6054 | -0.07873 | -0.1077 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1002 | 0.2460 | 1.553 | 0.4490 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8245 | -1.132 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 58</span>| 447.04861 | 1.009 | -2.019 | -0.9927 | -0.9476 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9252 | 1.054 | -2.796 | -1.779 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.878 | -0.9737 | -1.157 | -0.5487 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6291 | -0.6521 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 447.04861 | 93.85 | -6.319 | -1.017 | -0.1632 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.220 | 2.353 | 0.001429 | 0.6532 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08654 | 0.6862 | 0.6280 | 1.601 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.325 | 1.305 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 447.04861</span> | 93.85 | 0.001802 | 0.2657 | 0.8494 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.209 | 2.353 | 0.001429 | 0.6532 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08654 | 0.6862 | 0.6280 | 1.601 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.325 | 1.305 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 59</span>| 447.01937 | 1.009 | -2.012 | -0.9891 | -0.9459 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9304 | 1.053 | -2.785 | -1.798 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.853 | -0.9708 | -1.156 | -0.5534 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6439 | -0.6653 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 447.01937 | 93.80 | -6.312 | -1.013 | -0.1615 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.215 | 2.353 | 0.001597 | 0.6418 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08617 | 0.6884 | 0.6292 | 1.596 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.309 | 1.291 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 447.01937</span> | 93.80 | 0.001814 | 0.2664 | 0.8509 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.161 | 2.353 | 0.001597 | 0.6418 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08617 | 0.6884 | 0.6292 | 1.596 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.309 | 1.291 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 15.62 | 0.04451 | -0.6370 | 0.1658 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4720 | -0.4967 | -0.06076 | 0.2478 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.07878 | 0.2929 | 0.7908 | 0.7364 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2169 | -0.8458 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 60</span>| 447.00331 | 1.007 | -2.016 | -0.9874 | -0.9487 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9321 | 1.057 | -2.790 | -1.800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.856 | -0.9696 | -1.156 | -0.5575 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6423 | -0.6633 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 447.00331 | 93.68 | -6.316 | -1.012 | -0.1643 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.213 | 2.355 | 0.001526 | 0.6406 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08622 | 0.6893 | 0.6295 | 1.591 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.311 | 1.293 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 447.00331</span> | 93.68 | 0.001807 | 0.2667 | 0.8485 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.146 | 2.355 | 0.001526 | 0.6406 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08622 | 0.6893 | 0.6295 | 1.591 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.311 | 1.293 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.749 | 0.03581 | -0.6032 | 0.06997 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3775 | -0.4012 | -0.08782 | 0.2553 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.001918 | 0.1783 | 1.513 | 0.3567 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3333 | -0.7379 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 61</span>| 446.99944 | 1.008 | -2.018 | -0.9851 | -0.9476 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9359 | 1.058 | -2.787 | -1.806 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.859 | -0.9671 | -1.156 | -0.5614 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6427 | -0.6650 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 446.99944 | 93.70 | -6.318 | -1.009 | -0.1632 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.209 | 2.355 | 0.001564 | 0.6369 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08626 | 0.6911 | 0.6291 | 1.586 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.311 | 1.291 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 446.99944</span> | 93.70 | 0.001804 | 0.2671 | 0.8494 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.111 | 2.355 | 0.001564 | 0.6369 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08626 | 0.6911 | 0.6291 | 1.586 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.311 | 1.291 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.474 | 0.03546 | -0.4554 | 0.1057 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2777 | -0.4692 | -0.06549 | 0.06429 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09650 | 0.2331 | 0.6150 | 0.1626 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3753 | -0.8072 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 62</span>| 446.99641 | 1.007 | -2.020 | -0.9846 | -0.9460 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9366 | 1.059 | -2.790 | -1.808 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.868 | -0.9676 | -1.156 | -0.5621 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6420 | -0.6633 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 446.99641 | 93.67 | -6.320 | -1.009 | -0.1616 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.209 | 2.356 | 0.001530 | 0.6356 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08639 | 0.6908 | 0.6287 | 1.585 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.311 | 1.293 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 446.99641</span> | 93.67 | 0.001800 | 0.2672 | 0.8508 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.105 | 2.356 | 0.001530 | 0.6356 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08639 | 0.6908 | 0.6287 | 1.585 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.311 | 1.293 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.070 | 0.03317 | -0.4443 | 0.1488 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2478 | -0.4968 | -0.07674 | 0.09423 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.05318 | 0.2365 | 0.6058 | 0.5619 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3013 | -0.7224 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 63</span>| 446.99641 | 1.007 | -2.020 | -0.9846 | -0.9460 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9366 | 1.059 | -2.790 | -1.808 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.868 | -0.9676 | -1.156 | -0.5621 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6420 | -0.6633 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 446.99641 | 93.67 | -6.320 | -1.009 | -0.1616 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.209 | 2.356 | 0.001530 | 0.6356 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08639 | 0.6908 | 0.6287 | 1.585 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.311 | 1.293 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 446.99641</span> | 93.67 | 0.001800 | 0.2672 | 0.8508 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 9.105 | 2.356 | 0.001530 | 0.6356 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.08639 | 0.6908 | 0.6287 | 1.585 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.311 | 1.293 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>initial ETAs were nudged; (can control by foceiControl(etaNudge=., etaNudge2=))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>ETAs were reset to zero during optimization; (Can control by foceiControl(resetEtaP=.))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>gradient problems with initial estimate and covariance; see $scaleInfo</span> +<span class="r-in"><span class="va">f_nlmixr_dfop_sfo_saem_obs_tc</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_tc</span><span class="op">[</span><span class="st">"DFOP-SFO"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"saem"</span>,</span> +<span class="r-in"> error_model <span class="op">=</span> <span class="st">"obs_tc"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> 1: 90.7519 -4.8586 -1.7674 -3.5599 -2.0059 0.5800 4.8899 1.4250 1.1400 2.6923 0.4845 0.4370 10.2815 0.0004 9.0437 0.4047</span> +<span class="r-out co"><span class="r-pr">#></span> 2: 9.0763e+01 -5.2004e+00 -1.9605e+00 -4.2009e+00 -1.8767e+00 2.0341e-01 4.6454e+00 1.3537e+00 1.0830e+00 2.7771e+00 4.6027e-01 5.1181e-01 6.3469e+00 4.0033e-04 6.8216e+00 9.0448e-05</span> +<span class="r-out co"><span class="r-pr">#></span> 3: 9.0656e+01 -5.4820e+00 -2.0937e+00 -4.0962e+00 -1.5381e+00 -1.7136e-02 4.4131e+00 1.2861e+00 1.0288e+00 3.5620e+00 4.3726e-01 6.1217e-01 4.8763e+00 4.1436e-05 5.4967e+00 1.0148e-05</span> +<span class="r-out co"><span class="r-pr">#></span> 4: 9.0543e+01 -5.7744e+00 -2.1074e+00 -4.0393e+00 -1.3603e+00 -2.3531e-01 5.0162e+00 1.2218e+00 1.0041e+00 3.3839e+00 4.1540e-01 5.8157e-01 4.1029e+00 2.1466e-04 4.2869e+00 1.9419e-06</span> +<span class="r-out co"><span class="r-pr">#></span> 5: 91.1621 -6.0534 -2.0430 -4.0508 -1.2523 -0.2043 6.1015 1.1715 1.1998 3.2147 0.3946 0.5525 3.5979 0.0187 3.8221 0.0271</span> +<span class="r-out co"><span class="r-pr">#></span> 6: 91.1179 -5.9892 -2.0082 -4.1363 -1.1428 -0.1930 5.7964 1.1960 1.2360 3.4525 0.3749 0.5293 3.3091 0.0209 3.6230 0.0284</span> +<span class="r-out co"><span class="r-pr">#></span> 7: 91.6680 -5.9609 -2.0492 -4.1163 -1.0919 -0.1505 5.6134 1.6750 1.3055 3.2799 0.3631 0.5028 3.2412 0.0254 3.5108 0.0371</span> +<span class="r-out co"><span class="r-pr">#></span> 8: 91.6903 -5.9346 -2.0630 -4.0790 -1.1130 -0.0963 5.3327 2.2525 1.3524 3.1159 0.3449 0.4777 2.6165 0.0445 2.8556 0.0576</span> +<span class="r-out co"><span class="r-pr">#></span> 9: 92.2564 -5.7600 -2.0460 -4.1144 -1.0635 -0.0594 5.9616 2.1399 1.2848 2.9601 0.3277 0.4538 2.3593 0.0295 2.5704 0.0491</span> +<span class="r-out co"><span class="r-pr">#></span> 10: 92.2425 -5.7990 -2.0052 -4.0409 -1.0387 -0.1141 6.9547 2.1239 1.2205 2.8121 0.3113 0.4311 2.3237 0.0323 2.4227 0.0421</span> +<span class="r-out co"><span class="r-pr">#></span> 11: 92.4404 -5.6829 -2.0866 -4.0010 -1.0214 -0.0587 6.6790 2.0177 1.1595 2.6715 0.2957 0.4096 1.9963 0.0407 2.2478 0.0501</span> +<span class="r-out co"><span class="r-pr">#></span> 12: 92.0713 -5.8051 -2.1699 -4.0539 -0.9807 0.0174 6.7885 2.1380 1.1811 2.6017 0.2810 0.3891 1.8480 0.0502 2.0516 0.0522</span> +<span class="r-out co"><span class="r-pr">#></span> 13: 91.7214 -5.6954 -2.1579 -4.0944 -0.9935 -0.0195 6.4491 2.0311 1.1221 2.4716 0.2669 0.3696 1.8299 0.0531 1.9271 0.0520</span> +<span class="r-out co"><span class="r-pr">#></span> 14: 91.1978 -5.6733 -2.1988 -4.0794 -0.9387 0.0091 6.1267 1.9295 1.1589 2.3480 0.2536 0.3511 1.6357 0.0470 1.8899 0.0639</span> +<span class="r-out co"><span class="r-pr">#></span> 15: 91.3746 -5.5864 -2.1484 -4.1356 -0.9126 0.0045 5.8203 1.8330 1.2078 2.3265 0.2409 0.3336 1.6218 0.0428 1.6558 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 16: 91.5646 -5.4931 -2.1474 -4.1242 -0.9148 0.0179 5.5293 1.7414 1.1474 2.2733 0.2288 0.3169 1.6467 0.0377 1.6977 0.0600</span> +<span class="r-out co"><span class="r-pr">#></span> 17: 91.4767 -5.5885 -2.1424 -4.1386 -0.9308 0.0602 5.2528 1.9428 1.2141 2.1762 0.2174 0.3343 1.4916 0.0424 1.4326 0.0717</span> +<span class="r-out co"><span class="r-pr">#></span> 18: 90.9989 -5.6364 -2.1601 -4.1606 -0.9676 0.0694 4.9902 1.8457 1.2521 2.2899 0.2065 0.3279 1.4504 0.0471 1.4267 0.0700</span> +<span class="r-out co"><span class="r-pr">#></span> 19: 91.4050 -5.7347 -2.0985 -4.1476 -0.9656 0.0668 4.7407 2.3263 1.4064 2.2061 0.1962 0.3296 1.3679 0.0485 1.2735 0.0844</span> +<span class="r-out co"><span class="r-pr">#></span> 20: 91.2707 -5.7623 -2.1155 -4.1538 -0.9601 0.0425 4.5037 2.6509 1.3408 2.1958 0.1864 0.3576 1.3736 0.0452 1.3454 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 21: 91.6878 -5.8143 -2.1261 -4.1649 -0.9325 0.0333 4.7695 2.8996 1.3244 2.1300 0.1771 0.3509 1.4793 0.0508 1.0333 0.0839</span> +<span class="r-out co"><span class="r-pr">#></span> 22: 91.5363 -5.9047 -2.1358 -4.1655 -0.9207 0.0339 4.5310 3.4408 1.3022 2.1829 0.1682 0.3378 1.4260 0.0488 0.9436 0.0877</span> +<span class="r-out co"><span class="r-pr">#></span> 23: 91.9969 -5.9565 -2.1378 -4.1609 -0.9243 0.0701 4.3045 3.7239 1.3446 2.2424 0.1598 0.3209 1.4182 0.0412 0.9205 0.0873</span> +<span class="r-out co"><span class="r-pr">#></span> 24: 92.2835 -5.9272 -2.0883 -4.1651 -0.9248 0.0834 4.0892 3.7780 1.2773 2.2187 0.1518 0.3049 1.4749 0.0427 0.9837 0.0802</span> +<span class="r-out co"><span class="r-pr">#></span> 25: 92.3389 -6.1292 -2.1033 -4.2473 -0.9069 0.0593 3.8848 4.7059 1.2740 2.4323 0.1442 0.2896 1.3656 0.0493 0.9299 0.0798</span> +<span class="r-out co"><span class="r-pr">#></span> 26: 91.9840 -5.9821 -2.1124 -4.2150 -0.9100 0.1076 3.6905 4.4706 1.2103 2.4699 0.1458 0.2751 1.3200 0.0504 0.8256 0.0912</span> +<span class="r-out co"><span class="r-pr">#></span> 27: 92.4671 -5.8765 -2.0910 -4.2169 -0.9356 0.0483 3.5060 4.2471 1.2302 2.4791 0.1385 0.2614 1.4252 0.0520 0.8191 0.0836</span> +<span class="r-out co"><span class="r-pr">#></span> 28: 92.4130 -5.9480 -2.0870 -4.2191 -0.9338 0.0866 3.3859 4.1337 1.2210 2.4685 0.1412 0.2557 1.3860 0.0484 0.9189 0.0770</span> +<span class="r-out co"><span class="r-pr">#></span> 29: 92.3064 -5.7845 -2.0759 -4.2321 -0.9270 0.0855 4.2691 3.9271 1.3369 2.5457 0.1341 0.2922 1.3848 0.0513 0.9658 0.0785</span> +<span class="r-out co"><span class="r-pr">#></span> 30: 92.2109 -5.9347 -2.0725 -4.2042 -0.9074 0.0481 5.5659 3.9234 1.2701 2.4184 0.1370 0.2776 1.2925 0.0560 0.9058 0.0806</span> +<span class="r-out co"><span class="r-pr">#></span> 31: 91.8912 -5.7466 -2.0912 -4.1504 -0.9087 0.0443 5.2876 3.7272 1.2690 2.2975 0.1301 0.2637 1.3348 0.0517 0.8672 0.0840</span> +<span class="r-out co"><span class="r-pr">#></span> 32: 92.3866 -5.8560 -2.0979 -4.1547 -0.9044 0.0335 5.0232 3.5408 1.2761 2.3185 0.1307 0.2505 1.3558 0.0487 0.9422 0.0791</span> +<span class="r-out co"><span class="r-pr">#></span> 33: 92.4555 -5.6989 -2.0956 -4.1479 -0.9038 0.0447 4.7720 3.3638 1.3253 2.2962 0.1242 0.2380 1.4321 0.0432 0.8961 0.0799</span> +<span class="r-out co"><span class="r-pr">#></span> 34: 92.6307 -5.8831 -2.0769 -4.1319 -0.8946 0.0430 4.5334 3.7151 1.2785 2.2638 0.1201 0.2261 1.4076 0.0457 0.8269 0.0813</span> +<span class="r-out co"><span class="r-pr">#></span> 35: 92.5659 -5.9100 -2.0748 -4.1482 -0.9079 0.0563 4.6634 3.7452 1.3141 2.3378 0.1168 0.2148 1.3571 0.0451 0.8317 0.0831</span> +<span class="r-out co"><span class="r-pr">#></span> 36: 92.5738 -5.8574 -2.0981 -4.1214 -0.8963 0.0302 5.3272 3.7371 1.3359 2.2776 0.1331 0.2041 1.3308 0.0480 0.8953 0.0791</span> +<span class="r-out co"><span class="r-pr">#></span> 37: 92.1615 -5.7137 -2.0922 -4.1178 -0.9035 0.0455 5.4894 3.5503 1.2691 2.2508 0.1473 0.1939 1.3692 0.0495 0.9358 0.0800</span> +<span class="r-out co"><span class="r-pr">#></span> 38: 92.4421 -5.6978 -2.0905 -4.1275 -0.9052 0.0108 5.4295 3.3728 1.2057 2.2119 0.1432 0.1842 1.3421 0.0549 0.8932 0.0781</span> +<span class="r-out co"><span class="r-pr">#></span> 39: 92.3995 -5.6121 -2.0804 -4.1275 -0.8903 0.0270 5.1580 3.2041 1.1454 2.2119 0.1360 0.1978 1.3353 0.0524 0.9062 0.0775</span> +<span class="r-out co"><span class="r-pr">#></span> 40: 92.5616 -5.7907 -2.1099 -4.1127 -0.9074 0.0501 4.9001 3.0439 1.1582 2.1723 0.1387 0.1879 1.2981 0.0510 0.9517 0.0797</span> +<span class="r-out co"><span class="r-pr">#></span> 41: 92.2655 -5.6532 -2.0631 -4.1437 -0.9128 0.0346 4.6551 2.8917 1.1202 2.1498 0.1403 0.1785 1.4500 0.0461 0.7394 0.0903</span> +<span class="r-out co"><span class="r-pr">#></span> 42: 92.3218 -5.4916 -2.1072 -4.1312 -0.9310 0.0360 4.4224 2.7471 1.1648 2.1428 0.1332 0.1695 1.4034 0.0508 0.8131 0.0854</span> +<span class="r-out co"><span class="r-pr">#></span> 43: 92.6165 -5.5145 -2.0838 -4.1239 -0.9215 0.0347 4.2012 2.6098 1.1892 2.1202 0.1463 0.1611 1.3416 0.0507 0.8213 0.0847</span> +<span class="r-out co"><span class="r-pr">#></span> 44: 92.5385 -5.5590 -2.0872 -4.1376 -0.9210 0.0672 3.9912 2.4793 1.1416 2.2253 0.1450 0.1530 1.4008 0.0352 0.8639 0.0847</span> +<span class="r-out co"><span class="r-pr">#></span> 45: 92.2152 -5.6170 -2.1014 -4.1657 -0.9331 0.0781 3.7916 2.4382 1.1250 2.2378 0.1516 0.1556 1.4612 0.0329 1.0091 0.0820</span> +<span class="r-out co"><span class="r-pr">#></span> 46: 91.8943 -5.6650 -2.1329 -4.1649 -0.9241 0.1060 3.6020 2.6448 1.0705 2.3112 0.1441 0.1549 1.5047 0.0384 1.0179 0.0805</span> +<span class="r-out co"><span class="r-pr">#></span> 47: 91.8153 -5.5910 -2.1514 -4.1919 -0.9169 0.0885 3.4219 2.5125 1.0386 2.3140 0.1506 0.1620 1.4759 0.0375 1.1021 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 48: 91.6295 -5.5438 -2.1516 -4.1570 -0.8742 0.0851 3.2508 2.3869 1.0816 2.1983 0.1630 0.1786 1.4024 0.0405 1.1135 0.0732</span> +<span class="r-out co"><span class="r-pr">#></span> 49: 91.4363 -5.5847 -2.1732 -4.1794 -0.8634 0.0948 3.0883 2.4829 1.0865 2.2378 0.1549 0.1697 1.4314 0.0434 1.0529 0.0742</span> +<span class="r-out co"><span class="r-pr">#></span> 50: 91.3634 -5.5794 -2.1613 -4.1507 -0.8849 0.0862 2.9339 2.6404 1.0829 2.2519 0.1493 0.1612 1.3704 0.0446 1.0081 0.0736</span> +<span class="r-out co"><span class="r-pr">#></span> 51: 91.2150 -5.5503 -2.1675 -4.1432 -0.8749 0.1178 2.7872 2.7368 1.0605 2.2261 0.1418 0.1532 1.4312 0.0418 1.0380 0.0781</span> +<span class="r-out co"><span class="r-pr">#></span> 52: 91.4343 -5.6336 -2.2138 -4.1552 -0.8867 0.1391 2.6677 2.7022 1.0857 2.2588 0.1493 0.1455 1.3220 0.0469 0.9272 0.0761</span> +<span class="r-out co"><span class="r-pr">#></span> 53: 91.3310 -5.5185 -2.2340 -4.1430 -0.8855 0.1545 2.9130 2.5670 1.0720 2.3074 0.1532 0.1385 1.3224 0.0503 0.9688 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 54: 91.4342 -5.5008 -2.2086 -4.1777 -0.8720 0.1688 2.8202 2.4387 1.0624 2.4253 0.1631 0.1315 1.3186 0.0429 0.9425 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 55: 91.4983 -5.5944 -2.1709 -4.1211 -0.8638 0.1168 3.4789 2.5154 1.0549 2.3041 0.1557 0.1279 1.3800 0.0423 0.9620 0.0727</span> +<span class="r-out co"><span class="r-pr">#></span> 56: 91.5954 -5.5317 -2.1881 -4.1263 -0.8627 0.1366 4.1396 2.3896 1.0732 2.2684 0.1562 0.1221 1.3285 0.0431 1.0156 0.0708</span> +<span class="r-out co"><span class="r-pr">#></span> 57: 91.6591 -5.3839 -2.2082 -4.1122 -0.8929 0.1457 4.5073 2.2701 1.0672 2.3639 0.1539 0.1160 1.4074 0.0478 0.9796 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 58: 91.7434 -5.3597 -2.2068 -4.1214 -0.8912 0.1437 4.2819 2.1566 1.0605 2.4496 0.1667 0.1109 1.4274 0.0450 1.0782 0.0676</span> +<span class="r-out co"><span class="r-pr">#></span> 59: 91.6597 -5.4672 -2.1918 -4.1412 -0.9021 0.1657 4.0678 2.0488 1.1306 2.5245 0.1888 0.1054 1.4745 0.0391 1.1492 0.0670</span> +<span class="r-out co"><span class="r-pr">#></span> 60: 91.7565 -5.4513 -2.2051 -4.1618 -0.9013 0.1554 3.8644 1.9464 1.1728 2.6191 0.1793 0.1001 1.4135 0.0402 1.1572 0.0665</span> +<span class="r-out co"><span class="r-pr">#></span> 61: 91.9484 -5.5390 -2.1973 -4.1611 -0.9011 0.1318 3.6712 1.8963 1.1460 2.6242 0.1704 0.0951 1.3855 0.0481 1.1109 0.0634</span> +<span class="r-out co"><span class="r-pr">#></span> 62: 92.1661 -5.4985 -2.1729 -4.1352 -0.8887 0.1327 4.3155 1.8588 1.1087 2.5551 0.1633 0.0995 1.3847 0.0444 1.0736 0.0656</span> +<span class="r-out co"><span class="r-pr">#></span> 63: 92.1727 -5.4086 -2.1610 -4.1488 -0.8998 0.1451 4.6019 1.7659 1.1413 2.6020 0.1718 0.1152 1.4299 0.0404 1.2202 0.0603</span> +<span class="r-out co"><span class="r-pr">#></span> 64: 92.4331 -5.5220 -2.1121 -4.1300 -0.9428 0.1211 5.0354 1.8121 1.0982 2.6157 0.1775 0.1209 1.4168 0.0348 1.2148 0.0625</span> +<span class="r-out co"><span class="r-pr">#></span> 65: 92.1871 -5.6089 -2.1258 -4.1412 -0.9127 0.1399 4.7836 2.1060 1.1568 2.5971 0.1757 0.1148 1.4000 0.0336 1.0305 0.0707</span> +<span class="r-out co"><span class="r-pr">#></span> 66: 92.1419 -5.7752 -2.1344 -4.1493 -0.9237 0.1494 4.5444 2.7076 1.1563 2.6439 0.1740 0.1091 1.4238 0.0341 1.0285 0.0688</span> +<span class="r-out co"><span class="r-pr">#></span> 67: 92.1187 -5.5967 -2.1430 -4.1460 -0.9074 0.1245 4.3172 2.5722 1.2052 2.6139 0.1868 0.1104 1.4100 0.0381 1.0508 0.0703</span> +<span class="r-out co"><span class="r-pr">#></span> 68: 92.1123 -5.6882 -2.1481 -4.1269 -0.9083 0.1206 4.1014 2.5548 1.2021 2.4832 0.1781 0.1462 1.3099 0.0417 1.0099 0.0713</span> +<span class="r-out co"><span class="r-pr">#></span> 69: 92.2511 -5.6923 -2.1456 -4.1315 -0.9077 0.1421 4.3551 2.6261 1.1850 2.3591 0.1692 0.1389 1.3546 0.0416 0.9516 0.0762</span> +<span class="r-out co"><span class="r-pr">#></span> 70: 92.0291 -5.7376 -2.1689 -4.1364 -0.8908 0.1407 4.1373 3.0520 1.1595 2.2495 0.1608 0.1465 1.3226 0.0436 0.9904 0.0711</span> +<span class="r-out co"><span class="r-pr">#></span> 71: 91.7690 -5.7223 -2.1773 -4.1986 -0.9036 0.1831 3.9304 2.8994 1.1015 2.4335 0.1527 0.1602 1.3135 0.0450 0.9564 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 72: 91.4802 -5.7302 -2.2079 -4.2000 -0.8990 0.2112 3.7339 3.2965 1.1222 2.4612 0.1451 0.1622 1.3222 0.0426 1.0215 0.0717</span> +<span class="r-out co"><span class="r-pr">#></span> 73: 91.1247 -5.7803 -2.1827 -4.2214 -0.8876 0.1385 3.5472 3.2786 1.1612 2.5216 0.1650 0.1541 1.2811 0.0493 1.0076 0.0696</span> +<span class="r-out co"><span class="r-pr">#></span> 74: 90.9765 -5.6534 -2.1808 -4.2511 -0.8824 0.1308 3.8553 3.1146 1.1389 2.8140 0.1725 0.1464 1.2895 0.0518 1.0100 0.0707</span> +<span class="r-out co"><span class="r-pr">#></span> 75: 90.4805 -5.7293 -2.1481 -4.2613 -0.8704 0.1395 4.1255 2.9589 1.1623 2.7523 0.1713 0.1391 1.3112 0.0483 0.9439 0.0788</span> +<span class="r-out co"><span class="r-pr">#></span> 76: 90.3958 -5.7635 -2.1508 -4.2426 -0.8841 0.1402 4.7427 3.0223 1.2187 2.7243 0.1789 0.1321 1.3065 0.0468 0.9303 0.0758</span> +<span class="r-out co"><span class="r-pr">#></span> 77: 90.7518 -5.6517 -2.1498 -4.2773 -0.8730 0.1688 5.9340 2.8712 1.1840 2.8530 0.1828 0.1255 1.3553 0.0422 0.9755 0.0696</span> +<span class="r-out co"><span class="r-pr">#></span> 78: 91.0443 -5.7462 -2.1351 -4.2601 -0.8848 0.1746 5.6373 2.9912 1.1312 2.7659 0.1887 0.1192 1.3303 0.0410 0.8578 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 79: 90.9631 -5.7307 -2.1618 -4.2593 -0.8965 0.1944 5.7520 3.1324 1.1206 2.8212 0.1875 0.1340 1.3519 0.0449 0.9006 0.0799</span> +<span class="r-out co"><span class="r-pr">#></span> 80: 90.8703 -5.7665 -2.1989 -4.2476 -0.9122 0.1933 5.4644 3.4527 1.1063 2.7920 0.1781 0.1273 1.3014 0.0497 0.9305 0.0792</span> +<span class="r-out co"><span class="r-pr">#></span> 81: 90.7781 -5.8702 -2.1789 -4.2821 -0.8828 0.1793 5.1912 3.7553 1.0662 3.0568 0.1807 0.1209 1.3120 0.0472 0.9808 0.0772</span> +<span class="r-out co"><span class="r-pr">#></span> 82: 90.8137 -6.1164 -2.2001 -4.3046 -0.8912 0.1916 4.9316 4.9023 1.0714 3.1363 0.1716 0.1149 1.2724 0.0539 1.0644 0.0693</span> +<span class="r-out co"><span class="r-pr">#></span> 83: 90.9900 -6.2077 -2.1695 -4.3121 -0.8924 0.1722 6.7123 5.3290 1.1120 3.2733 0.1741 0.1091 1.2822 0.0510 1.0142 0.0715</span> +<span class="r-out co"><span class="r-pr">#></span> 84: 90.8158 -6.3282 -2.1595 -4.2907 -0.9096 0.1818 6.3767 5.9725 1.1342 3.2384 0.1763 0.1037 1.2704 0.0420 0.8891 0.0834</span> +<span class="r-out co"><span class="r-pr">#></span> 85: 90.5926 -6.2052 -2.1643 -4.2780 -0.9000 0.1579 6.0579 5.6739 1.1472 3.0765 0.1751 0.0985 1.3263 0.0433 0.9484 0.0814</span> +<span class="r-out co"><span class="r-pr">#></span> 86: 90.3804 -6.2707 -2.1470 -4.2627 -0.9260 0.1650 5.7550 5.5542 1.1135 2.9227 0.1956 0.0936 1.2747 0.0447 0.9731 0.0780</span> +<span class="r-out co"><span class="r-pr">#></span> 87: 90.8425 -6.4455 -2.1135 -4.2273 -0.9294 0.1491 5.4672 6.8599 1.0716 2.7765 0.1858 0.0928 1.3204 0.0427 1.0005 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 88: 91.2019 -6.2302 -2.1362 -4.1982 -0.9333 0.1615 5.1939 6.5169 1.1221 2.7203 0.1841 0.0928 1.2689 0.0466 0.9914 0.0771</span> +<span class="r-out co"><span class="r-pr">#></span> 89: 90.9907 -6.4173 -2.1174 -4.2493 -0.9182 0.1628 4.9342 6.2408 1.1719 2.9614 0.1749 0.1021 1.3580 0.0403 1.0171 0.0775</span> +<span class="r-out co"><span class="r-pr">#></span> 90: 91.1666 -6.5154 -2.1219 -4.2011 -0.9210 0.1594 4.6875 7.4895 1.1930 2.8133 0.1745 0.0970 1.2500 0.0432 0.9467 0.0799</span> +<span class="r-out co"><span class="r-pr">#></span> 91: 91.0165 -6.5918 -2.1465 -4.2231 -0.9079 0.1382 4.9772 7.3172 1.1706 2.6789 0.1810 0.1032 1.2958 0.0458 1.1223 0.0639</span> +<span class="r-out co"><span class="r-pr">#></span> 92: 91.5386 -6.6567 -2.1376 -4.2247 -0.9358 0.1696 5.5955 7.4188 1.1543 2.6339 0.1754 0.0980 1.2894 0.0463 0.9927 0.0764</span> +<span class="r-out co"><span class="r-pr">#></span> 93: 92.2552 -6.5096 -2.1645 -4.2340 -0.9393 0.1798 5.3157 7.0479 1.1612 2.6312 0.1718 0.0931 1.3698 0.0431 1.2649 0.0579</span> +<span class="r-out co"><span class="r-pr">#></span> 94: 91.7588 -6.4124 -2.1795 -4.2305 -0.9265 0.1842 5.8275 6.6955 1.1988 2.6403 0.1891 0.0884 1.3022 0.0481 1.0741 0.0713</span> +<span class="r-out co"><span class="r-pr">#></span> 95: 91.6694 -6.2975 -2.1946 -4.2442 -0.9392 0.2004 5.5361 6.3607 1.1399 2.7164 0.1796 0.1027 1.2519 0.0513 1.0982 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 96: 91.2252 -6.0124 -2.2316 -4.2701 -0.8946 0.2375 5.2593 6.0427 1.0829 2.7921 0.2024 0.1147 1.3343 0.0426 1.3064 0.0560</span> +<span class="r-out co"><span class="r-pr">#></span> 97: 91.0388 -5.9178 -2.2563 -4.2703 -0.9093 0.2304 5.6825 5.7405 1.0890 2.7678 0.2113 0.1090 1.3517 0.0484 1.4160 0.0493</span> +<span class="r-out co"><span class="r-pr">#></span> 98: 90.9013 -6.1325 -2.2597 -4.2776 -0.9133 0.2447 5.7546 5.4535 1.1028 2.6806 0.2130 0.1182 1.2983 0.0451 1.2436 0.0584</span> +<span class="r-out co"><span class="r-pr">#></span> 99: 91.2086 -6.0047 -2.2719 -4.2972 -0.9136 0.2738 5.4668 5.1808 1.1776 2.7160 0.2132 0.1123 1.3301 0.0431 1.1850 0.0628</span> +<span class="r-out co"><span class="r-pr">#></span> 100: 91.3181 -5.9175 -2.2311 -4.3202 -0.8947 0.2844 5.1935 4.9218 1.1187 2.8660 0.2289 0.1471 1.3409 0.0371 0.9566 0.0806</span> +<span class="r-out co"><span class="r-pr">#></span> 101: 91.5112 -5.7721 -2.2292 -4.3060 -0.8842 0.3006 6.3617 4.6757 1.0628 2.7227 0.2174 0.1500 1.3269 0.0407 1.2002 0.0592</span> +<span class="r-out co"><span class="r-pr">#></span> 102: 91.5205 -5.9982 -2.2162 -4.3041 -0.8813 0.3065 7.7957 4.4419 1.0320 2.7176 0.2290 0.1474 1.3218 0.0392 0.9685 0.0783</span> +<span class="r-out co"><span class="r-pr">#></span> 103: 91.2416 -5.7012 -2.2204 -4.3198 -0.8610 0.3180 7.4059 4.2198 1.0242 2.5817 0.2175 0.1714 1.3003 0.0395 0.9472 0.0825</span> +<span class="r-out co"><span class="r-pr">#></span> 104: 91.2662 -5.8136 -2.2357 -4.3063 -0.8700 0.3110 7.0356 4.0088 1.0024 2.4701 0.2067 0.1939 1.2806 0.0407 1.0387 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 105: 91.4688 -5.7922 -2.2204 -4.3319 -0.8703 0.2767 6.6838 3.8084 0.9751 2.6368 0.1963 0.1967 1.3320 0.0470 1.2043 0.0580</span> +<span class="r-out co"><span class="r-pr">#></span> 106: 91.3665 -5.8505 -2.2225 -4.3614 -0.8757 0.2922 7.1982 3.6180 1.0018 2.6378 0.1865 0.2132 1.2613 0.0464 1.0683 0.0693</span> +<span class="r-out co"><span class="r-pr">#></span> 107: 91.4934 -5.8933 -2.1993 -4.3433 -0.9112 0.3267 6.8383 3.7379 0.9616 2.5329 0.1772 0.2169 1.2911 0.0449 1.0688 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 108: 92.1268 -5.7807 -2.1863 -4.4348 -0.9273 0.3235 6.4964 3.5510 1.0093 2.9025 0.1718 0.2061 1.3153 0.0414 0.8982 0.0796</span> +<span class="r-out co"><span class="r-pr">#></span> 109: 91.6585 -5.9778 -2.2083 -4.3550 -0.9061 0.3339 6.1715 4.5778 1.0600 2.7574 0.1755 0.2163 1.2754 0.0382 0.8100 0.0868</span> +<span class="r-out co"><span class="r-pr">#></span> 110: 92.0456 -5.6784 -2.2236 -4.3483 -0.8911 0.3022 5.8630 4.3489 1.0427 2.6195 0.1667 0.2472 1.3782 0.0336 0.7819 0.0931</span> +<span class="r-out co"><span class="r-pr">#></span> 111: 92.2862 -5.6624 -2.1985 -4.3680 -0.9178 0.3156 5.5698 4.1315 1.0149 2.5443 0.1622 0.2348 1.3541 0.0415 0.7848 0.0868</span> +<span class="r-out co"><span class="r-pr">#></span> 112: 92.5436 -5.6572 -2.2134 -4.3290 -0.9267 0.3025 5.2913 3.9249 1.0720 2.5118 0.1541 0.2231 1.3798 0.0385 0.9087 0.0799</span> +<span class="r-out co"><span class="r-pr">#></span> 113: 92.5970 -5.6263 -2.2030 -4.3044 -0.9123 0.2856 5.0268 3.7287 1.1371 2.4674 0.1764 0.2119 1.3007 0.0455 0.8651 0.0850</span> +<span class="r-out co"><span class="r-pr">#></span> 114: 92.9227 -5.6379 -2.2032 -4.2926 -0.9187 0.3282 4.7754 3.5422 1.1022 2.4105 0.1676 0.2013 1.3103 0.0439 0.9003 0.0815</span> +<span class="r-out co"><span class="r-pr">#></span> 115: 92.7678 -5.8033 -2.1888 -4.2988 -0.9406 0.3026 4.5367 3.3651 1.1127 2.5043 0.1592 0.1913 1.3643 0.0420 0.9649 0.0800</span> +<span class="r-out co"><span class="r-pr">#></span> 116: 92.0655 -5.8531 -2.2033 -4.2989 -0.9487 0.3013 4.3098 3.6792 1.1260 2.4981 0.1513 0.1817 1.2783 0.0445 0.9812 0.0818</span> +<span class="r-out co"><span class="r-pr">#></span> 117: 92.2258 -5.7861 -2.2095 -4.3393 -0.9399 0.2998 4.0943 3.4952 1.0697 2.7102 0.1437 0.1752 1.3037 0.0426 0.9067 0.0786</span> +<span class="r-out co"><span class="r-pr">#></span> 118: 92.3560 -5.8080 -2.2058 -4.3166 -0.9480 0.2743 4.6025 3.3205 1.0709 2.6198 0.1432 0.1747 1.2850 0.0481 0.9236 0.0769</span> +<span class="r-out co"><span class="r-pr">#></span> 119: 92.0489 -5.7726 -2.1972 -4.2740 -0.9087 0.2627 4.3723 3.1544 1.0892 2.4888 0.1620 0.1660 1.2659 0.0435 0.8389 0.0832</span> +<span class="r-out co"><span class="r-pr">#></span> 120: 91.9163 -5.8211 -2.2101 -4.2770 -0.9142 0.2674 4.1537 3.1700 1.0985 2.5003 0.1795 0.1577 1.2289 0.0454 0.9280 0.0826</span> +<span class="r-out co"><span class="r-pr">#></span> 121: 92.0274 -5.7601 -2.1916 -4.2686 -0.9055 0.2571 3.9460 3.1181 1.1026 2.3985 0.1908 0.1498 1.3015 0.0432 0.9363 0.0807</span> +<span class="r-out co"><span class="r-pr">#></span> 122: 92.2933 -5.7972 -2.2019 -4.2888 -0.8932 0.2679 3.7487 3.1755 1.0809 2.3976 0.1843 0.1636 1.2918 0.0433 0.8760 0.0803</span> +<span class="r-out co"><span class="r-pr">#></span> 123: 92.3361 -5.8903 -2.1745 -4.3386 -0.9157 0.2665 3.5613 3.8794 1.1308 2.5838 0.1751 0.1555 1.3219 0.0421 0.8987 0.0806</span> +<span class="r-out co"><span class="r-pr">#></span> 124: 92.5677 -6.0471 -2.1638 -4.2764 -0.9325 0.2645 3.3832 4.6152 1.1336 2.4546 0.1664 0.1526 1.2938 0.0375 0.9412 0.0798</span> +<span class="r-out co"><span class="r-pr">#></span> 125: 92.7852 -5.9841 -2.1661 -4.2825 -0.9373 0.2866 3.2141 4.3844 1.0770 2.3788 0.1581 0.1727 1.3137 0.0417 0.9228 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 126: 92.7867 -5.9126 -2.1636 -4.2413 -0.9141 0.2756 3.0534 4.1652 1.0857 2.2921 0.1502 0.1994 1.2428 0.0450 0.8206 0.0795</span> +<span class="r-out co"><span class="r-pr">#></span> 127: 92.8733 -5.9110 -2.1546 -4.2269 -0.9258 0.2531 2.9007 3.9569 1.0914 2.3822 0.1426 0.2029 1.3043 0.0369 0.8206 0.0795</span> +<span class="r-out co"><span class="r-pr">#></span> 128: 93.0457 -5.9202 -2.1505 -4.2076 -0.9466 0.2463 3.3353 3.7591 1.0647 2.3012 0.1355 0.2180 1.3420 0.0385 0.8503 0.0803</span> +<span class="r-out co"><span class="r-pr">#></span> 129: 92.9207 -5.9882 -2.1704 -4.2204 -0.9319 0.2464 4.3160 4.4368 1.1187 2.3415 0.1386 0.2316 1.2546 0.0435 0.8777 0.0830</span> +<span class="r-out co"><span class="r-pr">#></span> 130: 92.2660 -6.2043 -2.1712 -4.2251 -0.9276 0.2186 4.4370 5.1440 1.0817 2.3426 0.1338 0.2200 1.2733 0.0476 0.9132 0.0753</span> +<span class="r-out co"><span class="r-pr">#></span> 131: 92.1286 -6.4163 -2.1634 -4.2642 -0.9223 0.2300 4.2151 6.2253 1.0614 2.5012 0.1333 0.2090 1.2690 0.0430 0.8201 0.0814</span> +<span class="r-out co"><span class="r-pr">#></span> 132: 92.0287 -6.4297 -2.1522 -4.2717 -0.9259 0.2250 4.0044 6.1979 1.0791 2.5146 0.1314 0.1985 1.2736 0.0449 0.8671 0.0784</span> +<span class="r-out co"><span class="r-pr">#></span> 133: 91.6843 -6.1415 -2.1685 -4.2553 -0.9349 0.2209 3.8041 5.8880 1.1445 2.4277 0.1248 0.2026 1.3381 0.0426 0.9129 0.0858</span> +<span class="r-out co"><span class="r-pr">#></span> 134: 91.6928 -6.1408 -2.1467 -4.2709 -0.9270 0.2648 3.6139 5.5936 1.0873 2.5602 0.1305 0.1925 1.3202 0.0416 0.7626 0.0936</span> +<span class="r-out co"><span class="r-pr">#></span> 135: 91.7984 -6.0371 -2.1673 -4.2572 -0.9497 0.2480 3.4332 5.3139 1.0649 2.4322 0.1389 0.1829 1.2592 0.0544 0.9459 0.0831</span> +<span class="r-out co"><span class="r-pr">#></span> 136: 91.9754 -6.1770 -2.1769 -4.2311 -0.9401 0.2435 3.2616 5.0482 1.0717 2.3106 0.1691 0.1737 1.3170 0.0436 1.0497 0.0816</span> +<span class="r-out co"><span class="r-pr">#></span> 137: 92.1546 -6.1216 -2.1731 -4.2278 -0.9401 0.2492 3.0985 4.9378 1.0200 2.1950 0.1606 0.1988 1.4019 0.0421 1.0200 0.0766</span> +<span class="r-out co"><span class="r-pr">#></span> 138: 92.2370 -5.9463 -2.1794 -4.1949 -0.9321 0.2460 2.9436 4.6909 1.0203 2.1200 0.1535 0.1947 1.3378 0.0425 0.9448 0.0804</span> +<span class="r-out co"><span class="r-pr">#></span> 139: 92.2025 -5.8849 -2.1820 -4.1868 -0.9200 0.2294 2.9458 4.4564 0.9875 2.1260 0.1759 0.2080 1.3244 0.0428 1.0110 0.0778</span> +<span class="r-out co"><span class="r-pr">#></span> 140: 91.8182 -5.7494 -2.1569 -4.1998 -0.9095 0.2318 2.7985 4.2336 1.0015 2.1507 0.1830 0.2113 1.3502 0.0432 0.7716 0.0922</span> +<span class="r-out co"><span class="r-pr">#></span> 141: 91.8292 -5.9568 -2.1640 -4.2109 -0.9122 0.2130 4.4608 4.0219 1.0180 2.1032 0.1739 0.2057 1.3594 0.0419 0.8088 0.0883</span> +<span class="r-out co"><span class="r-pr">#></span> 142: 91.9995 -6.0927 -2.1471 -4.2313 -0.9091 0.1875 4.5415 4.7705 1.0571 2.1286 0.1810 0.1954 1.4145 0.0406 0.8943 0.0847</span> +<span class="r-out co"><span class="r-pr">#></span> 143: 91.9160 -5.9892 -2.1546 -4.2043 -0.9355 0.1819 4.3145 4.5320 1.1337 2.1453 0.1888 0.2208 1.3449 0.0394 1.0910 0.0797</span> +<span class="r-out co"><span class="r-pr">#></span> 144: 92.0136 -5.9765 -2.1643 -4.2346 -0.9448 0.2455 4.3041 4.3054 1.1130 2.1300 0.1817 0.3253 1.3828 0.0340 1.0535 0.0873</span> +<span class="r-out co"><span class="r-pr">#></span> 145: 92.3893 -6.2224 -2.1211 -4.2316 -0.9405 0.2285 5.2279 4.9099 1.0573 2.1037 0.1727 0.3091 1.3797 0.0340 1.0160 0.0832</span> +<span class="r-out co"><span class="r-pr">#></span> 146: 92.6097 -6.2204 -2.1406 -4.2210 -0.9217 0.1762 4.9665 5.4466 1.0724 2.1658 0.1640 0.2936 1.4421 0.0408 1.2412 0.0674</span> +<span class="r-out co"><span class="r-pr">#></span> 147: 92.8499 -6.0091 -2.1165 -4.2234 -0.9682 0.1783 4.7182 5.1743 1.0188 2.1714 0.1722 0.2789 1.4545 0.0397 1.4472 0.0556</span> +<span class="r-out co"><span class="r-pr">#></span> 148: 92.6602 -5.8003 -2.1059 -4.2132 -0.9282 0.2102 4.4823 4.9156 1.0106 2.1075 0.1880 0.2684 1.4013 0.0413 1.0748 0.0758</span> +<span class="r-out co"><span class="r-pr">#></span> 149: 92.7388 -5.8727 -2.1569 -4.2185 -0.9266 0.1868 4.2581 4.6698 1.1447 2.0851 0.1786 0.2550 1.3137 0.0413 0.9963 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 150: 92.7348 -5.7926 -2.1184 -4.2257 -0.9324 0.1966 4.0452 4.4363 1.1760 2.1508 0.1697 0.2704 1.3792 0.0363 0.8204 0.0889</span> +<span class="r-out co"><span class="r-pr">#></span> 151: 92.7968 -5.7301 -2.1179 -4.1959 -0.9275 0.1927 3.8430 4.2145 1.1707 2.1702 0.1842 0.2569 1.3789 0.0387 0.7890 0.0873</span> +<span class="r-out co"><span class="r-pr">#></span> 152: 92.9011 -5.7417 -2.1622 -4.2086 -0.9215 0.1784 2.0089 3.0670 1.1984 2.2253 0.1814 0.2507 1.3431 0.0395 0.9622 0.0780</span> +<span class="r-out co"><span class="r-pr">#></span> 153: 92.8020 -5.7707 -2.1494 -4.2128 -0.9228 0.1818 2.2261 2.9648 1.1192 2.3058 0.1749 0.2548 1.3671 0.0369 0.9507 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 154: 92.5217 -5.8043 -2.1447 -4.2074 -0.9303 0.1766 2.7638 3.1314 1.1141 2.2814 0.1811 0.2389 1.3250 0.0408 1.0538 0.0689</span> +<span class="r-out co"><span class="r-pr">#></span> 155: 92.8765 -5.5586 -2.1275 -4.1639 -0.9320 0.1434 2.4217 2.4658 1.1231 2.1314 0.1746 0.2426 1.3785 0.0407 0.9682 0.0796</span> +<span class="r-out co"><span class="r-pr">#></span> 156: 93.0074 -5.6819 -2.1343 -4.1819 -0.9382 0.1587 1.4756 2.7496 1.1200 2.1700 0.1849 0.2320 1.3643 0.0395 1.0875 0.0653</span> +<span class="r-out co"><span class="r-pr">#></span> 157: 92.7950 -5.6827 -2.1178 -4.1808 -0.9553 0.1585 1.1607 2.5156 1.1129 2.2109 0.1724 0.2366 1.4045 0.0374 1.1322 0.0676</span> +<span class="r-out co"><span class="r-pr">#></span> 158: 92.7684 -5.7106 -2.0933 -4.2149 -0.9717 0.1602 1.4884 2.6532 1.1269 2.1388 0.1838 0.2666 1.4009 0.0348 0.8728 0.0832</span> +<span class="r-out co"><span class="r-pr">#></span> 159: 93.0980 -5.8911 -2.1297 -4.2160 -0.9660 0.1407 1.6034 3.3765 1.1182 2.1661 0.1705 0.2804 1.3557 0.0430 1.0076 0.0776</span> +<span class="r-out co"><span class="r-pr">#></span> 160: 93.1849 -5.9433 -2.1177 -4.1735 -0.9436 0.1324 1.8692 4.0887 1.1252 2.0213 0.1642 0.2922 1.3251 0.0386 0.8586 0.0820</span> +<span class="r-out co"><span class="r-pr">#></span> 161: 93.4771 -5.7768 -2.0899 -4.1697 -0.9670 0.1043 2.0938 2.9110 1.1069 1.9538 0.1820 0.3046 1.3270 0.0413 0.8220 0.0855</span> +<span class="r-out co"><span class="r-pr">#></span> 162: 93.4961 -5.6516 -2.0965 -4.1633 -0.9708 0.1263 2.2053 2.3022 1.1179 1.9555 0.1758 0.2891 1.3158 0.0417 0.9943 0.0768</span> +<span class="r-out co"><span class="r-pr">#></span> 163: 93.1627 -5.5944 -2.1527 -4.1633 -0.9488 0.1452 2.9600 2.3291 1.1027 1.9555 0.1766 0.3000 1.3626 0.0376 0.9790 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 164: 92.7951 -5.6646 -2.1539 -4.1699 -0.9447 0.1863 2.9195 2.7599 1.0794 1.9511 0.1651 0.2918 1.4091 0.0357 1.1005 0.0709</span> +<span class="r-out co"><span class="r-pr">#></span> 165: 92.6045 -5.5927 -2.1842 -4.1770 -0.9436 0.1939 2.2014 2.3213 1.0622 1.9775 0.1671 0.2899 1.3945 0.0372 1.0533 0.0694</span> +<span class="r-out co"><span class="r-pr">#></span> 166: 92.6660 -5.5922 -2.1438 -4.1611 -0.9441 0.1767 1.8951 2.3445 1.1025 2.0399 0.1802 0.2802 1.4229 0.0354 1.1552 0.0682</span> +<span class="r-out co"><span class="r-pr">#></span> 167: 92.4353 -5.5118 -2.1415 -4.1730 -0.9124 0.1827 1.5029 1.8145 1.0701 2.0090 0.1727 0.2642 1.4525 0.0362 1.0577 0.0754</span> +<span class="r-out co"><span class="r-pr">#></span> 168: 92.3761 -5.5522 -2.1625 -4.1911 -0.9114 0.1782 1.2703 2.0808 1.0814 2.0588 0.1810 0.2658 1.3973 0.0364 0.9874 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 169: 92.5240 -5.6102 -2.1396 -4.1793 -0.8972 0.1722 1.3115 2.2750 1.0759 2.0910 0.2147 0.2549 1.3553 0.0392 0.9770 0.0759</span> +<span class="r-out co"><span class="r-pr">#></span> 170: 92.3827 -5.5942 -2.1231 -4.1847 -0.9338 0.1525 1.5707 2.3778 1.0542 2.0824 0.2042 0.2519 1.4424 0.0363 1.1270 0.0687</span> +<span class="r-out co"><span class="r-pr">#></span> 171: 92.1706 -5.6171 -2.1619 -4.1926 -0.9056 0.1390 1.0935 2.2869 1.1239 2.1697 0.1946 0.2624 1.2980 0.0411 0.9988 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 172: 92.1491 -5.5704 -2.1447 -4.1913 -0.9285 0.1649 1.0292 2.2160 1.1231 2.1905 0.1860 0.2518 1.3154 0.0375 1.0152 0.0772</span> +<span class="r-out co"><span class="r-pr">#></span> 173: 91.9987 -5.5411 -2.1434 -4.1803 -0.9056 0.1585 0.6511 1.9989 1.0892 2.2283 0.1899 0.2413 1.3814 0.0380 1.1733 0.0693</span> +<span class="r-out co"><span class="r-pr">#></span> 174: 92.0377 -5.5419 -2.1081 -4.1928 -0.9057 0.1418 0.9013 2.0933 1.1813 2.2773 0.1756 0.2559 1.4419 0.0343 0.9942 0.0801</span> +<span class="r-out co"><span class="r-pr">#></span> 175: 92.0266 -5.5125 -2.1014 -4.1775 -0.9119 0.1371 0.7194 2.0624 1.1848 2.2328 0.1754 0.2504 1.3987 0.0353 1.0838 0.0728</span> +<span class="r-out co"><span class="r-pr">#></span> 176: 92.0365 -5.5658 -2.0914 -4.1646 -0.8956 0.1096 0.7557 2.0588 1.1642 2.1610 0.1617 0.2722 1.3658 0.0347 0.9405 0.0757</span> +<span class="r-out co"><span class="r-pr">#></span> 177: 91.8661 -5.6799 -2.0950 -4.1695 -0.9010 0.1193 0.8835 2.8899 1.1394 2.1886 0.1809 0.2777 1.3841 0.0351 0.9178 0.0794</span> +<span class="r-out co"><span class="r-pr">#></span> 178: 91.9392 -5.7853 -2.1139 -4.1711 -0.9190 0.1222 0.6673 3.0461 1.1712 2.1948 0.1576 0.2237 1.3623 0.0383 0.9060 0.0795</span> +<span class="r-out co"><span class="r-pr">#></span> 179: 92.0116 -5.7560 -2.1418 -4.1711 -0.9153 0.1034 0.4356 2.9139 1.1653 2.1948 0.1497 0.2364 1.3387 0.0392 0.9327 0.0793</span> +<span class="r-out co"><span class="r-pr">#></span> 180: 92.1013 -5.7920 -2.1368 -4.1654 -0.9059 0.0912 0.3859 3.2592 1.1357 2.1744 0.1570 0.2337 1.3622 0.0408 1.0299 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 181: 92.1032 -5.8125 -2.1260 -4.1791 -0.9404 0.1731 0.4091 3.0817 1.1113 2.2356 0.1572 0.2742 1.4509 0.0340 0.9180 0.0865</span> +<span class="r-out co"><span class="r-pr">#></span> 182: 92.1315 -5.7991 -2.1327 -4.1737 -0.9319 0.1519 0.3145 3.0292 1.1520 2.1360 0.1661 0.2482 1.4105 0.0361 1.1338 0.0748</span> +<span class="r-out co"><span class="r-pr">#></span> 183: 92.1350 -6.0470 -2.1264 -4.1707 -0.9525 0.1787 0.2045 3.8296 1.1229 2.1369 0.1735 0.2453 1.3132 0.0350 1.0507 0.0759</span> +<span class="r-out co"><span class="r-pr">#></span> 184: 92.0539 -5.9856 -2.1289 -4.1968 -0.9281 0.1789 0.1166 3.9425 1.0558 2.2320 0.1658 0.2253 1.3390 0.0355 1.1271 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 185: 92.0755 -6.0524 -2.1385 -4.2076 -0.9313 0.1794 0.1193 4.2430 1.0465 2.3571 0.1566 0.2152 1.3777 0.0368 1.2013 0.0631</span> +<span class="r-out co"><span class="r-pr">#></span> 186: 92.1639 -6.0663 -2.1399 -4.1869 -0.9311 0.1817 0.1392 4.4053 1.0495 2.4857 0.1532 0.2331 1.3751 0.0365 1.0497 0.0697</span> +<span class="r-out co"><span class="r-pr">#></span> 187: 92.1759 -6.3052 -2.1469 -4.2221 -0.9428 0.1970 0.1356 5.5622 0.9953 2.3367 0.1451 0.2359 1.3754 0.0367 1.0969 0.0656</span> +<span class="r-out co"><span class="r-pr">#></span> 188: 92.1744 -6.0494 -2.1406 -4.2445 -0.9595 0.2089 0.1364 4.3818 0.9882 2.4074 0.1480 0.2364 1.3709 0.0396 1.1259 0.0642</span> +<span class="r-out co"><span class="r-pr">#></span> 189: 92.1989 -6.1255 -2.1138 -4.2037 -0.9368 0.1796 0.1444 4.6756 0.9840 2.3786 0.1502 0.2303 1.3979 0.0393 1.2011 0.0630</span> +<span class="r-out co"><span class="r-pr">#></span> 190: 92.0944 -6.1343 -2.1536 -4.2106 -0.9267 0.2105 0.1288 4.4977 1.0475 2.3593 0.1443 0.2396 1.3247 0.0384 1.1304 0.0711</span> +<span class="r-out co"><span class="r-pr">#></span> 191: 92.1238 -6.0639 -2.1462 -4.2883 -0.9311 0.2155 0.1246 4.1066 1.0428 2.6836 0.1442 0.2344 1.4041 0.0344 1.1631 0.0684</span> +<span class="r-out co"><span class="r-pr">#></span> 192: 92.1328 -6.0743 -2.1232 -4.3119 -0.9586 0.2319 0.1192 4.1348 1.0020 2.7067 0.1466 0.2515 1.4039 0.0355 1.0021 0.0772</span> +<span class="r-out co"><span class="r-pr">#></span> 193: 92.0881 -5.8697 -2.1298 -4.2691 -0.9309 0.2295 0.1050 3.4476 0.9879 2.5496 0.1344 0.2348 1.4677 0.0351 1.0332 0.0705</span> +<span class="r-out co"><span class="r-pr">#></span> 194: 92.1086 -5.7557 -2.1176 -4.3249 -0.9029 0.2183 0.0702 2.7793 1.0043 2.8853 0.1460 0.2213 1.4733 0.0325 1.0929 0.0681</span> +<span class="r-out co"><span class="r-pr">#></span> 195: 92.1265 -5.8976 -2.1506 -4.2932 -0.9267 0.2511 0.0593 3.4959 0.9881 2.6806 0.1278 0.2505 1.6138 0.0350 1.1327 0.0703</span> +<span class="r-out co"><span class="r-pr">#></span> 196: 92.1316 -5.7018 -2.1627 -4.2889 -0.9278 0.2392 0.0717 2.9210 1.0160 2.7067 0.1470 0.2350 1.5063 0.0418 1.0525 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 197: 92.1756 -5.7899 -2.1604 -4.2819 -0.9248 0.2765 0.0754 2.9991 1.0167 2.6170 0.1465 0.2314 1.4982 0.0387 1.0504 0.0774</span> +<span class="r-out co"><span class="r-pr">#></span> 198: 92.2153 -5.8248 -2.1571 -4.2245 -0.9350 0.2195 0.0651 3.0128 0.9196 2.3123 0.1451 0.2363 1.3965 0.0453 1.1561 0.0650</span> +<span class="r-out co"><span class="r-pr">#></span> 199: 92.1935 -5.8187 -2.1505 -4.2123 -0.9452 0.2406 0.0535 3.0017 0.9553 2.2771 0.1338 0.2415 1.4485 0.0407 1.0647 0.0699</span> +<span class="r-out co"><span class="r-pr">#></span> 200: 92.2308 -5.6732 -2.1578 -4.2182 -0.9324 0.2330 0.0618 2.4070 1.0687 2.2978 0.1513 0.2199 1.4101 0.0385 1.0283 0.0741</span> +<span class="r-out co"><span class="r-pr">#></span> 201: 92.2305 -5.6796 -2.1604 -4.2064 -0.9320 0.2262 0.0530 2.4360 1.0551 2.2994 0.1529 0.2219 1.3653 0.0407 1.0115 0.0757</span> +<span class="r-out co"><span class="r-pr">#></span> 202: 92.2259 -5.7201 -2.1550 -4.2058 -0.9263 0.2208 0.0461 2.6422 1.0351 2.2888 0.1520 0.2100 1.3739 0.0418 1.0474 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 203: 92.2212 -5.7539 -2.1457 -4.2037 -0.9303 0.2163 0.0422 2.8480 1.0403 2.2723 0.1465 0.2070 1.3973 0.0404 1.0518 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 204: 92.2164 -5.8068 -2.1371 -4.2093 -0.9300 0.2163 0.0383 3.1313 1.0426 2.2984 0.1423 0.2091 1.4025 0.0391 1.0284 0.0737</span> +<span class="r-out co"><span class="r-pr">#></span> 205: 92.2120 -5.8371 -2.1369 -4.2142 -0.9308 0.2156 0.0347 3.2786 1.0392 2.3249 0.1390 0.2048 1.4115 0.0385 1.0161 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 206: 92.2071 -5.8681 -2.1391 -4.2176 -0.9287 0.2158 0.0336 3.4917 1.0442 2.3461 0.1388 0.2041 1.4017 0.0394 0.9977 0.0735</span> +<span class="r-out co"><span class="r-pr">#></span> 207: 92.2078 -5.8966 -2.1424 -4.2230 -0.9286 0.2181 0.0337 3.6741 1.0456 2.3743 0.1369 0.2009 1.3988 0.0397 0.9792 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 208: 92.2077 -5.8972 -2.1459 -4.2249 -0.9300 0.2208 0.0340 3.6775 1.0460 2.3889 0.1362 0.1985 1.3969 0.0394 0.9729 0.0742</span> +<span class="r-out co"><span class="r-pr">#></span> 209: 92.2091 -5.8831 -2.1488 -4.2271 -0.9326 0.2227 0.0337 3.6019 1.0465 2.4005 0.1380 0.1967 1.3949 0.0395 0.9745 0.0741</span> +<span class="r-out co"><span class="r-pr">#></span> 210: 92.2115 -5.8806 -2.1490 -4.2282 -0.9349 0.2238 0.0324 3.5652 1.0516 2.4211 0.1386 0.1979 1.3941 0.0391 0.9820 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 211: 92.2151 -5.8791 -2.1516 -4.2291 -0.9363 0.2258 0.0318 3.5315 1.0458 2.4465 0.1390 0.1989 1.3918 0.0394 0.9901 0.0735</span> +<span class="r-out co"><span class="r-pr">#></span> 212: 92.2189 -5.8789 -2.1532 -4.2297 -0.9380 0.2269 0.0312 3.4989 1.0434 2.4718 0.1409 0.1993 1.3884 0.0394 1.0007 0.0732</span> +<span class="r-out co"><span class="r-pr">#></span> 213: 92.2226 -5.8714 -2.1556 -4.2287 -0.9395 0.2255 0.0313 3.4460 1.0440 2.4800 0.1413 0.1993 1.3859 0.0397 1.0157 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 214: 92.2233 -5.8706 -2.1553 -4.2279 -0.9394 0.2237 0.0309 3.4283 1.0431 2.4809 0.1414 0.2003 1.3849 0.0399 1.0186 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 215: 92.2242 -5.8750 -2.1536 -4.2285 -0.9390 0.2212 0.0312 3.4442 1.0455 2.4800 0.1417 0.2015 1.3830 0.0401 1.0126 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 216: 92.2252 -5.8788 -2.1521 -4.2277 -0.9393 0.2192 0.0316 3.4718 1.0459 2.4791 0.1410 0.2028 1.3817 0.0402 1.0046 0.0726</span> +<span class="r-out co"><span class="r-pr">#></span> 217: 92.2255 -5.8869 -2.1516 -4.2268 -0.9400 0.2177 0.0322 3.5295 1.0456 2.4751 0.1407 0.2042 1.3814 0.0401 1.0011 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 218: 92.2230 -5.8819 -2.1511 -4.2259 -0.9400 0.2164 0.0327 3.5004 1.0473 2.4693 0.1399 0.2051 1.3784 0.0401 0.9962 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 219: 92.2206 -5.8761 -2.1499 -4.2269 -0.9393 0.2156 0.0325 3.4736 1.0494 2.4667 0.1399 0.2066 1.3794 0.0399 0.9925 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 220: 92.2185 -5.8775 -2.1494 -4.2267 -0.9380 0.2150 0.0331 3.4894 1.0511 2.4596 0.1396 0.2090 1.3788 0.0398 0.9881 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 221: 92.2180 -5.8774 -2.1499 -4.2271 -0.9369 0.2142 0.0328 3.4873 1.0518 2.4559 0.1399 0.2109 1.3776 0.0399 0.9842 0.0735</span> +<span class="r-out co"><span class="r-pr">#></span> 222: 92.2191 -5.8833 -2.1503 -4.2280 -0.9359 0.2127 0.0328 3.5384 1.0518 2.4533 0.1400 0.2114 1.3778 0.0400 0.9825 0.0735</span> +<span class="r-out co"><span class="r-pr">#></span> 223: 92.2199 -5.8831 -2.1486 -4.2288 -0.9343 0.2112 0.0326 3.5474 1.0539 2.4515 0.1396 0.2127 1.3795 0.0398 0.9806 0.0735</span> +<span class="r-out co"><span class="r-pr">#></span> 224: 92.2206 -5.8870 -2.1467 -4.2283 -0.9331 0.2093 0.0324 3.5619 1.0550 2.4482 0.1395 0.2133 1.3805 0.0395 0.9792 0.0735</span> +<span class="r-out co"><span class="r-pr">#></span> 225: 92.2218 -5.8929 -2.1459 -4.2289 -0.9328 0.2086 0.0322 3.6001 1.0548 2.4492 0.1388 0.2142 1.3804 0.0393 0.9809 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 226: 92.2228 -5.8909 -2.1440 -4.2293 -0.9322 0.2082 0.0320 3.6007 1.0566 2.4513 0.1383 0.2143 1.3826 0.0390 0.9815 0.0737</span> +<span class="r-out co"><span class="r-pr">#></span> 227: 92.2234 -5.8838 -2.1444 -4.2304 -0.9319 0.2088 0.0319 3.5748 1.0551 2.4562 0.1381 0.2140 1.3814 0.0390 0.9836 0.0736</span> +<span class="r-out co"><span class="r-pr">#></span> 228: 92.2243 -5.8835 -2.1444 -4.2314 -0.9326 0.2093 0.0317 3.5756 1.0526 2.4607 0.1377 0.2143 1.3824 0.0389 0.9901 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 229: 92.2251 -5.8916 -2.1442 -4.2307 -0.9330 0.2095 0.0318 3.6344 1.0501 2.4580 0.1371 0.2148 1.3850 0.0388 0.9930 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 230: 92.2250 -5.8951 -2.1442 -4.2303 -0.9334 0.2107 0.0318 3.6533 1.0475 2.4550 0.1369 0.2150 1.3872 0.0387 0.9953 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 231: 92.2247 -5.8964 -2.1444 -4.2300 -0.9345 0.2119 0.0322 3.6564 1.0446 2.4549 0.1368 0.2151 1.3899 0.0388 0.9991 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 232: 92.2230 -5.8982 -2.1451 -4.2306 -0.9352 0.2132 0.0326 3.6643 1.0422 2.4591 0.1365 0.2155 1.3934 0.0388 1.0052 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 233: 92.2223 -5.9022 -2.1455 -4.2327 -0.9354 0.2141 0.0329 3.6824 1.0396 2.4697 0.1362 0.2165 1.3970 0.0388 1.0107 0.0726</span> +<span class="r-out co"><span class="r-pr">#></span> 234: 92.2200 -5.9075 -2.1457 -4.2324 -0.9348 0.2140 0.0335 3.7056 1.0364 2.4735 0.1366 0.2174 1.3977 0.0388 1.0163 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 235: 92.2171 -5.9094 -2.1457 -4.2338 -0.9342 0.2142 0.0342 3.7222 1.0339 2.4854 0.1372 0.2189 1.3999 0.0389 1.0228 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 236: 92.2161 -5.9195 -2.1464 -4.2368 -0.9340 0.2140 0.0346 3.7789 1.0329 2.4986 0.1376 0.2200 1.4007 0.0389 1.0281 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 237: 92.2163 -5.9214 -2.1469 -4.2390 -0.9330 0.2143 0.0347 3.7862 1.0329 2.5074 0.1378 0.2195 1.4030 0.0389 1.0320 0.0719</span> +<span class="r-out co"><span class="r-pr">#></span> 238: 92.2165 -5.9203 -2.1473 -4.2399 -0.9326 0.2143 0.0347 3.7781 1.0336 2.5100 0.1381 0.2186 1.4031 0.0388 1.0347 0.0719</span> +<span class="r-out co"><span class="r-pr">#></span> 239: 92.2173 -5.9212 -2.1471 -4.2403 -0.9325 0.2136 0.0344 3.7908 1.0350 2.5128 0.1384 0.2175 1.4021 0.0389 1.0352 0.0718</span> +<span class="r-out co"><span class="r-pr">#></span> 240: 92.2178 -5.9217 -2.1470 -4.2394 -0.9322 0.2133 0.0342 3.8082 1.0363 2.5118 0.1384 0.2169 1.4025 0.0387 1.0345 0.0719</span> +<span class="r-out co"><span class="r-pr">#></span> 241: 92.2177 -5.9200 -2.1470 -4.2383 -0.9318 0.2136 0.0340 3.8123 1.0381 2.5110 0.1385 0.2161 1.4028 0.0387 1.0336 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 242: 92.2170 -5.9109 -2.1478 -4.2371 -0.9308 0.2136 0.0340 3.7766 1.0387 2.5090 0.1385 0.2157 1.4027 0.0386 1.0322 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 243: 92.2165 -5.9029 -2.1484 -4.2371 -0.9300 0.2140 0.0340 3.7433 1.0389 2.5128 0.1386 0.2150 1.4032 0.0385 1.0342 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 244: 92.2161 -5.8998 -2.1489 -4.2374 -0.9294 0.2143 0.0340 3.7242 1.0392 2.5173 0.1386 0.2148 1.4030 0.0384 1.0343 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 245: 92.2153 -5.9048 -2.1494 -4.2370 -0.9291 0.2149 0.0339 3.7491 1.0399 2.5182 0.1386 0.2146 1.4019 0.0383 1.0317 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 246: 92.2147 -5.9093 -2.1498 -4.2371 -0.9289 0.2156 0.0339 3.7727 1.0409 2.5218 0.1384 0.2145 1.4016 0.0382 1.0309 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 247: 92.2143 -5.9124 -2.1503 -4.2368 -0.9286 0.2159 0.0338 3.7972 1.0408 2.5232 0.1383 0.2144 1.4012 0.0382 1.0297 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 248: 92.2137 -5.9122 -2.1500 -4.2367 -0.9286 0.2160 0.0336 3.8036 1.0409 2.5245 0.1382 0.2141 1.4022 0.0381 1.0272 0.0727</span> +<span class="r-out co"><span class="r-pr">#></span> 249: 92.2133 -5.9101 -2.1501 -4.2364 -0.9288 0.2160 0.0334 3.7984 1.0406 2.5268 0.1383 0.2136 1.4031 0.0381 1.0273 0.0726</span> +<span class="r-out co"><span class="r-pr">#></span> 250: 92.2139 -5.9115 -2.1502 -4.2368 -0.9289 0.2167 0.0335 3.8015 1.0412 2.5326 0.1380 0.2132 1.4035 0.0381 1.0261 0.0727</span> +<span class="r-out co"><span class="r-pr">#></span> 251: 92.2132 -5.9123 -2.1502 -4.2373 -0.9297 0.2170 0.0338 3.8015 1.0421 2.5362 0.1376 0.2126 1.4053 0.0379 1.0274 0.0727</span> +<span class="r-out co"><span class="r-pr">#></span> 252: 92.2128 -5.9106 -2.1502 -4.2366 -0.9299 0.2174 0.0338 3.7931 1.0427 2.5345 0.1371 0.2120 1.4062 0.0379 1.0262 0.0728</span> +<span class="r-out co"><span class="r-pr">#></span> 253: 92.2118 -5.9098 -2.1492 -4.2364 -0.9297 0.2173 0.0340 3.8011 1.0420 2.5338 0.1369 0.2121 1.4074 0.0378 1.0232 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 254: 92.2107 -5.9104 -2.1479 -4.2362 -0.9296 0.2171 0.0341 3.8085 1.0398 2.5330 0.1366 0.2123 1.4093 0.0377 1.0230 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 255: 92.2103 -5.9133 -2.1466 -4.2359 -0.9299 0.2166 0.0341 3.8219 1.0381 2.5346 0.1363 0.2122 1.4105 0.0377 1.0230 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 256: 92.2094 -5.9171 -2.1453 -4.2356 -0.9299 0.2161 0.0341 3.8498 1.0366 2.5366 0.1362 0.2123 1.4114 0.0375 1.0239 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 257: 92.2091 -5.9169 -2.1441 -4.2353 -0.9302 0.2153 0.0341 3.8529 1.0347 2.5385 0.1360 0.2118 1.4126 0.0375 1.0265 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 258: 92.2089 -5.9191 -2.1431 -4.2349 -0.9301 0.2145 0.0340 3.8608 1.0331 2.5392 0.1359 0.2119 1.4126 0.0375 1.0282 0.0728</span> +<span class="r-out co"><span class="r-pr">#></span> 259: 92.2093 -5.9249 -2.1426 -4.2337 -0.9301 0.2145 0.0341 3.8853 1.0321 2.5385 0.1361 0.2120 1.4114 0.0374 1.0280 0.0728</span> +<span class="r-out co"><span class="r-pr">#></span> 260: 92.2095 -5.9297 -2.1415 -4.2328 -0.9303 0.2146 0.0339 3.9108 1.0302 2.5367 0.1358 0.2125 1.4112 0.0373 1.0265 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 261: 92.2096 -5.9341 -2.1407 -4.2321 -0.9307 0.2147 0.0338 3.9343 1.0278 2.5343 0.1356 0.2131 1.4121 0.0373 1.0272 0.0728</span> +<span class="r-out co"><span class="r-pr">#></span> 262: 92.2094 -5.9342 -2.1398 -4.2312 -0.9310 0.2149 0.0336 3.9314 1.0254 2.5313 0.1356 0.2139 1.4115 0.0372 1.0249 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 263: 92.2088 -5.9376 -2.1388 -4.2304 -0.9313 0.2153 0.0334 3.9452 1.0232 2.5289 0.1357 0.2143 1.4109 0.0371 1.0228 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 264: 92.2077 -5.9410 -2.1379 -4.2301 -0.9317 0.2153 0.0333 3.9571 1.0204 2.5265 0.1356 0.2147 1.4105 0.0371 1.0224 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 265: 92.2069 -5.9454 -2.1374 -4.2296 -0.9322 0.2154 0.0332 3.9800 1.0182 2.5230 0.1356 0.2147 1.4115 0.0371 1.0232 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 266: 92.2067 -5.9463 -2.1370 -4.2291 -0.9324 0.2155 0.0330 3.9809 1.0165 2.5217 0.1354 0.2148 1.4121 0.0371 1.0220 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 267: 92.2064 -5.9492 -2.1368 -4.2282 -0.9329 0.2154 0.0328 3.9874 1.0150 2.5199 0.1357 0.2150 1.4124 0.0370 1.0233 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 268: 92.2065 -5.9468 -2.1360 -4.2276 -0.9333 0.2155 0.0328 3.9722 1.0133 2.5171 0.1362 0.2155 1.4133 0.0369 1.0243 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 269: 92.2066 -5.9438 -2.1352 -4.2267 -0.9335 0.2151 0.0328 3.9526 1.0122 2.5142 0.1367 0.2154 1.4140 0.0369 1.0244 0.0728</span> +<span class="r-out co"><span class="r-pr">#></span> 270: 92.2067 -5.9388 -2.1351 -4.2259 -0.9339 0.2151 0.0326 3.9283 1.0112 2.5114 0.1370 0.2157 1.4137 0.0368 1.0240 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 271: 92.2069 -5.9350 -2.1344 -4.2252 -0.9342 0.2152 0.0324 3.9072 1.0107 2.5094 0.1370 0.2158 1.4136 0.0367 1.0222 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 272: 92.2069 -5.9317 -2.1341 -4.2246 -0.9348 0.2153 0.0321 3.8870 1.0104 2.5082 0.1372 0.2157 1.4139 0.0366 1.0219 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 273: 92.2068 -5.9289 -2.1340 -4.2240 -0.9348 0.2152 0.0320 3.8711 1.0101 2.5075 0.1373 0.2159 1.4146 0.0366 1.0232 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 274: 92.2067 -5.9271 -2.1337 -4.2239 -0.9350 0.2153 0.0318 3.8569 1.0101 2.5085 0.1377 0.2157 1.4144 0.0366 1.0239 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 275: 92.2063 -5.9264 -2.1339 -4.2235 -0.9353 0.2156 0.0317 3.8476 1.0097 2.5078 0.1382 0.2157 1.4143 0.0365 1.0256 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 276: 92.2059 -5.9271 -2.1339 -4.2231 -0.9354 0.2160 0.0316 3.8417 1.0097 2.5074 0.1387 0.2156 1.4132 0.0365 1.0260 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 277: 92.2059 -5.9283 -2.1342 -4.2225 -0.9356 0.2163 0.0316 3.8412 1.0094 2.5073 0.1393 0.2155 1.4122 0.0364 1.0283 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 278: 92.2062 -5.9278 -2.1341 -4.2220 -0.9361 0.2166 0.0318 3.8331 1.0081 2.5069 0.1397 0.2154 1.4117 0.0364 1.0321 0.0727</span> +<span class="r-out co"><span class="r-pr">#></span> 279: 92.2061 -5.9264 -2.1341 -4.2214 -0.9363 0.2168 0.0319 3.8188 1.0072 2.5051 0.1402 0.2155 1.4111 0.0364 1.0342 0.0726</span> +<span class="r-out co"><span class="r-pr">#></span> 280: 92.2057 -5.9263 -2.1344 -4.2211 -0.9365 0.2167 0.0321 3.8114 1.0072 2.5061 0.1406 0.2148 1.4108 0.0365 1.0361 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 281: 92.2048 -5.9269 -2.1344 -4.2208 -0.9365 0.2166 0.0324 3.8082 1.0076 2.5077 0.1410 0.2142 1.4098 0.0365 1.0363 0.0726</span> +<span class="r-out co"><span class="r-pr">#></span> 282: 92.2045 -5.9257 -2.1347 -4.2205 -0.9366 0.2165 0.0328 3.8040 1.0082 2.5092 0.1413 0.2138 1.4090 0.0365 1.0364 0.0726</span> +<span class="r-out co"><span class="r-pr">#></span> 283: 92.2038 -5.9235 -2.1348 -4.2201 -0.9363 0.2163 0.0331 3.7955 1.0089 2.5108 0.1415 0.2134 1.4086 0.0365 1.0362 0.0726</span> +<span class="r-out co"><span class="r-pr">#></span> 284: 92.2032 -5.9234 -2.1348 -4.2198 -0.9359 0.2162 0.0335 3.7945 1.0100 2.5118 0.1420 0.2129 1.4083 0.0365 1.0362 0.0726</span> +<span class="r-out co"><span class="r-pr">#></span> 285: 92.2028 -5.9236 -2.1347 -4.2193 -0.9360 0.2161 0.0339 3.7930 1.0104 2.5124 0.1422 0.2125 1.4080 0.0365 1.0373 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 286: 92.2020 -5.9221 -2.1344 -4.2187 -0.9355 0.2156 0.0341 3.7872 1.0104 2.5134 0.1425 0.2121 1.4074 0.0364 1.0377 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 287: 92.2013 -5.9213 -2.1341 -4.2183 -0.9354 0.2154 0.0343 3.7888 1.0098 2.5151 0.1428 0.2119 1.4075 0.0364 1.0390 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 288: 92.2003 -5.9195 -2.1339 -4.2182 -0.9355 0.2152 0.0343 3.7831 1.0090 2.5180 0.1430 0.2116 1.4082 0.0364 1.0408 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 289: 92.1995 -5.9186 -2.1339 -4.2182 -0.9355 0.2154 0.0343 3.7805 1.0083 2.5217 0.1429 0.2115 1.4085 0.0364 1.0426 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 290: 92.1984 -5.9180 -2.1339 -4.2177 -0.9354 0.2153 0.0343 3.7767 1.0080 2.5219 0.1427 0.2113 1.4083 0.0365 1.0429 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 291: 92.1975 -5.9167 -2.1334 -4.2175 -0.9355 0.2151 0.0343 3.7701 1.0080 2.5230 0.1427 0.2108 1.4083 0.0364 1.0439 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 292: 92.1971 -5.9175 -2.1330 -4.2166 -0.9356 0.2144 0.0342 3.7722 1.0081 2.5227 0.1426 0.2107 1.4079 0.0364 1.0443 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 293: 92.1963 -5.9188 -2.1330 -4.2157 -0.9357 0.2141 0.0342 3.7768 1.0083 2.5242 0.1425 0.2103 1.4073 0.0364 1.0439 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 294: 92.1953 -5.9189 -2.1328 -4.2157 -0.9357 0.2136 0.0344 3.7727 1.0078 2.5294 0.1427 0.2095 1.4079 0.0364 1.0456 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 295: 92.1946 -5.9171 -2.1329 -4.2153 -0.9355 0.2135 0.0345 3.7623 1.0081 2.5331 0.1426 0.2090 1.4080 0.0364 1.0462 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 296: 92.1940 -5.9154 -2.1329 -4.2150 -0.9354 0.2130 0.0346 3.7523 1.0082 2.5354 0.1425 0.2084 1.4075 0.0365 1.0463 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 297: 92.1934 -5.9128 -2.1330 -4.2145 -0.9351 0.2127 0.0349 3.7395 1.0084 2.5373 0.1423 0.2079 1.4072 0.0365 1.0453 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 298: 92.1932 -5.9128 -2.1332 -4.2138 -0.9347 0.2120 0.0350 3.7372 1.0085 2.5368 0.1423 0.2075 1.4068 0.0365 1.0449 0.0720</span> +<span class="r-out co"><span class="r-pr">#></span> 299: 92.1927 -5.9120 -2.1333 -4.2131 -0.9344 0.2112 0.0352 3.7324 1.0088 2.5366 0.1422 0.2070 1.4059 0.0366 1.0441 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 300: 92.1921 -5.9097 -2.1335 -4.2122 -0.9343 0.2105 0.0353 3.7211 1.0096 2.5357 0.1425 0.2066 1.4050 0.0367 1.0443 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 301: 92.1915 -5.9081 -2.1337 -4.2116 -0.9343 0.2098 0.0355 3.7110 1.0104 2.5355 0.1427 0.2061 1.4041 0.0368 1.0448 0.0721</span> +<span class="r-out co"><span class="r-pr">#></span> 302: 92.1912 -5.9067 -2.1340 -4.2108 -0.9342 0.2092 0.0355 3.7052 1.0114 2.5348 0.1428 0.2055 1.4036 0.0369 1.0442 0.0722</span> +<span class="r-out co"><span class="r-pr">#></span> 303: 92.1913 -5.9039 -2.1342 -4.2113 -0.9342 0.2087 0.0355 3.6925 1.0123 2.5408 0.1430 0.2049 1.4028 0.0369 1.0436 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 304: 92.1920 -5.9012 -2.1342 -4.2119 -0.9342 0.2081 0.0356 3.6781 1.0129 2.5476 0.1432 0.2044 1.4026 0.0369 1.0436 0.0723</span> +<span class="r-out co"><span class="r-pr">#></span> 305: 92.1923 -5.8984 -2.1343 -4.2123 -0.9341 0.2076 0.0354 3.6633 1.0134 2.5525 0.1434 0.2038 1.4022 0.0370 1.0434 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 306: 92.1926 -5.8977 -2.1343 -4.2121 -0.9343 0.2072 0.0354 3.6603 1.0144 2.5567 0.1436 0.2030 1.4022 0.0369 1.0431 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 307: 92.1931 -5.8970 -2.1346 -4.2124 -0.9344 0.2068 0.0353 3.6555 1.0154 2.5617 0.1438 0.2021 1.4017 0.0370 1.0431 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 308: 92.1935 -5.8963 -2.1347 -4.2127 -0.9343 0.2062 0.0351 3.6486 1.0166 2.5665 0.1439 0.2012 1.4017 0.0370 1.0431 0.0724</span> +<span class="r-out co"><span class="r-pr">#></span> 309: 92.1934 -5.8965 -2.1349 -4.2130 -0.9344 0.2058 0.0350 3.6454 1.0180 2.5711 0.1439 0.2003 1.4013 0.0370 1.0427 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 310: 92.1935 -5.8965 -2.1349 -4.2133 -0.9345 0.2055 0.0350 3.6401 1.0193 2.5761 0.1439 0.1993 1.4013 0.0371 1.0418 0.0725</span> +<span class="r-out co"><span class="r-pr">#></span> 311: 92.1931 -5.8976 -2.1349 -4.2139 -0.9346 0.2052 0.0349 3.6416 1.0207 2.5820 0.1437 0.1982 1.4015 0.0370 1.0411 0.0726</span> +<span class="r-out co"><span class="r-pr">#></span> 312: 92.1928 -5.8995 -2.1350 -4.2149 -0.9349 0.2053 0.0350 3.6472 1.0222 2.5902 0.1437 0.1972 1.4018 0.0370 1.0412 0.0727</span> +<span class="r-out co"><span class="r-pr">#></span> 313: 92.1922 -5.8999 -2.1350 -4.2159 -0.9352 0.2055 0.0350 3.6450 1.0236 2.5989 0.1436 0.1962 1.4017 0.0369 1.0407 0.0728</span> +<span class="r-out co"><span class="r-pr">#></span> 314: 92.1913 -5.9021 -2.1353 -4.2171 -0.9353 0.2055 0.0350 3.6532 1.0244 2.6086 0.1437 0.1951 1.4019 0.0369 1.0409 0.0728</span> +<span class="r-out co"><span class="r-pr">#></span> 315: 92.1905 -5.9033 -2.1358 -4.2178 -0.9354 0.2055 0.0351 3.6591 1.0252 2.6142 0.1438 0.1941 1.4018 0.0369 1.0420 0.0728</span> +<span class="r-out co"><span class="r-pr">#></span> 316: 92.1895 -5.9043 -2.1358 -4.2186 -0.9352 0.2053 0.0352 3.6648 1.0266 2.6207 0.1441 0.1934 1.4016 0.0369 1.0420 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 317: 92.1888 -5.9041 -2.1359 -4.2200 -0.9352 0.2052 0.0352 3.6673 1.0278 2.6312 0.1444 0.1926 1.4014 0.0369 1.0416 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 318: 92.1879 -5.9039 -2.1360 -4.2212 -0.9352 0.2052 0.0354 3.6670 1.0292 2.6380 0.1446 0.1919 1.4010 0.0369 1.0403 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 319: 92.1871 -5.9046 -2.1361 -4.2222 -0.9353 0.2052 0.0354 3.6709 1.0306 2.6432 0.1448 0.1912 1.4008 0.0369 1.0394 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 320: 92.1863 -5.9023 -2.1365 -4.2229 -0.9355 0.2052 0.0355 3.6602 1.0318 2.6466 0.1448 0.1903 1.4011 0.0369 1.0398 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 321: 92.1855 -5.8996 -2.1368 -4.2236 -0.9354 0.2053 0.0355 3.6491 1.0329 2.6505 0.1448 0.1895 1.4017 0.0369 1.0402 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 322: 92.1850 -5.8979 -2.1370 -4.2243 -0.9353 0.2057 0.0356 3.6399 1.0341 2.6534 0.1447 0.1888 1.4020 0.0368 1.0394 0.0732</span> +<span class="r-out co"><span class="r-pr">#></span> 323: 92.1844 -5.8984 -2.1371 -4.2251 -0.9352 0.2059 0.0356 3.6431 1.0346 2.6566 0.1447 0.1882 1.4026 0.0368 1.0389 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 324: 92.1838 -5.8967 -2.1372 -4.2257 -0.9353 0.2062 0.0356 3.6392 1.0351 2.6598 0.1445 0.1875 1.4031 0.0368 1.0382 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 325: 92.1835 -5.8936 -2.1374 -4.2264 -0.9351 0.2066 0.0355 3.6288 1.0352 2.6633 0.1444 0.1869 1.4043 0.0367 1.0391 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 326: 92.1837 -5.8936 -2.1376 -4.2276 -0.9350 0.2071 0.0354 3.6296 1.0354 2.6684 0.1444 0.1865 1.4043 0.0367 1.0380 0.0735</span> +<span class="r-out co"><span class="r-pr">#></span> 327: 92.1837 -5.8943 -2.1378 -4.2289 -0.9347 0.2076 0.0354 3.6348 1.0357 2.6746 0.1444 0.1860 1.4043 0.0366 1.0380 0.0735</span> +<span class="r-out co"><span class="r-pr">#></span> 328: 92.1838 -5.8953 -2.1380 -4.2297 -0.9345 0.2081 0.0354 3.6456 1.0360 2.6776 0.1444 0.1856 1.4043 0.0366 1.0379 0.0735</span> +<span class="r-out co"><span class="r-pr">#></span> 329: 92.1836 -5.8974 -2.1383 -4.2305 -0.9342 0.2085 0.0356 3.6591 1.0361 2.6802 0.1444 0.1852 1.4043 0.0366 1.0385 0.0735</span> +<span class="r-out co"><span class="r-pr">#></span> 330: 92.1832 -5.8994 -2.1387 -4.2305 -0.9342 0.2088 0.0358 3.6715 1.0364 2.6798 0.1443 0.1849 1.4037 0.0367 1.0378 0.0736</span> +<span class="r-out co"><span class="r-pr">#></span> 331: 92.1826 -5.8983 -2.1391 -4.2302 -0.9342 0.2091 0.0357 3.6670 1.0368 2.6800 0.1442 0.1845 1.4038 0.0367 1.0379 0.0736</span> +<span class="r-out co"><span class="r-pr">#></span> 332: 92.1824 -5.8959 -2.1396 -4.2301 -0.9341 0.2097 0.0357 3.6576 1.0375 2.6792 0.1442 0.1842 1.4034 0.0367 1.0372 0.0737</span> +<span class="r-out co"><span class="r-pr">#></span> 333: 92.1826 -5.8937 -2.1401 -4.2304 -0.9340 0.2104 0.0356 3.6487 1.0383 2.6798 0.1442 0.1838 1.4029 0.0367 1.0360 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 334: 92.1825 -5.8911 -2.1407 -4.2311 -0.9339 0.2112 0.0355 3.6378 1.0390 2.6825 0.1444 0.1834 1.4025 0.0367 1.0349 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 335: 92.1830 -5.8887 -2.1411 -4.2317 -0.9336 0.2118 0.0355 3.6294 1.0396 2.6850 0.1444 0.1830 1.4022 0.0367 1.0338 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 336: 92.1834 -5.8872 -2.1413 -4.2324 -0.9334 0.2124 0.0356 3.6249 1.0402 2.6880 0.1444 0.1825 1.4024 0.0367 1.0339 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 337: 92.1835 -5.8869 -2.1416 -4.2334 -0.9332 0.2131 0.0356 3.6252 1.0411 2.6926 0.1443 0.1821 1.4029 0.0366 1.0330 0.0741</span> +<span class="r-out co"><span class="r-pr">#></span> 338: 92.1839 -5.8882 -2.1418 -4.2346 -0.9333 0.2137 0.0357 3.6332 1.0421 2.6972 0.1441 0.1815 1.4036 0.0366 1.0324 0.0742</span> +<span class="r-out co"><span class="r-pr">#></span> 339: 92.1845 -5.8869 -2.1420 -4.2358 -0.9332 0.2143 0.0357 3.6261 1.0428 2.7021 0.1439 0.1810 1.4043 0.0366 1.0322 0.0742</span> +<span class="r-out co"><span class="r-pr">#></span> 340: 92.1846 -5.8863 -2.1421 -4.2367 -0.9331 0.2147 0.0357 3.6242 1.0436 2.7060 0.1439 0.1804 1.4049 0.0365 1.0328 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 341: 92.1848 -5.8847 -2.1421 -4.2378 -0.9330 0.2150 0.0356 3.6177 1.0442 2.7099 0.1439 0.1798 1.4056 0.0366 1.0334 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 342: 92.1848 -5.8838 -2.1421 -4.2390 -0.9330 0.2154 0.0355 3.6114 1.0449 2.7151 0.1438 0.1792 1.4064 0.0365 1.0332 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 343: 92.1849 -5.8840 -2.1423 -4.2398 -0.9330 0.2157 0.0353 3.6109 1.0459 2.7191 0.1438 0.1785 1.4060 0.0366 1.0334 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 344: 92.1851 -5.8839 -2.1423 -4.2406 -0.9330 0.2159 0.0352 3.6092 1.0467 2.7229 0.1440 0.1779 1.4060 0.0365 1.0338 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 345: 92.1850 -5.8841 -2.1424 -4.2414 -0.9331 0.2162 0.0352 3.6070 1.0472 2.7263 0.1441 0.1774 1.4056 0.0365 1.0341 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 346: 92.1848 -5.8839 -2.1424 -4.2420 -0.9333 0.2164 0.0352 3.6048 1.0479 2.7292 0.1443 0.1769 1.4058 0.0365 1.0344 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 347: 92.1846 -5.8835 -2.1425 -4.2427 -0.9334 0.2166 0.0353 3.6017 1.0495 2.7330 0.1444 0.1763 1.4053 0.0365 1.0343 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 348: 92.1846 -5.8825 -2.1427 -4.2434 -0.9336 0.2168 0.0353 3.5968 1.0508 2.7362 0.1445 0.1757 1.4051 0.0365 1.0343 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 349: 92.1846 -5.8820 -2.1432 -4.2444 -0.9337 0.2172 0.0352 3.5937 1.0519 2.7412 0.1446 0.1752 1.4047 0.0365 1.0343 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 350: 92.1845 -5.8817 -2.1435 -4.2454 -0.9338 0.2179 0.0351 3.5899 1.0526 2.7460 0.1448 0.1747 1.4042 0.0365 1.0339 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 351: 92.1844 -5.8824 -2.1439 -4.2468 -0.9338 0.2184 0.0350 3.5917 1.0535 2.7531 0.1448 0.1740 1.4041 0.0365 1.0336 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 352: 92.1840 -5.8840 -2.1442 -4.2482 -0.9338 0.2189 0.0350 3.6013 1.0543 2.7603 0.1450 0.1734 1.4044 0.0364 1.0342 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 353: 92.1838 -5.8848 -2.1445 -4.2492 -0.9336 0.2194 0.0349 3.6030 1.0552 2.7652 0.1451 0.1730 1.4043 0.0364 1.0338 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 354: 92.1838 -5.8835 -2.1449 -4.2501 -0.9336 0.2197 0.0349 3.5961 1.0563 2.7697 0.1452 0.1723 1.4044 0.0364 1.0342 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 355: 92.1837 -5.8826 -2.1453 -4.2511 -0.9335 0.2199 0.0348 3.5910 1.0569 2.7757 0.1451 0.1718 1.4053 0.0364 1.0348 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 356: 92.1835 -5.8826 -2.1456 -4.2520 -0.9334 0.2198 0.0348 3.5922 1.0577 2.7815 0.1451 0.1712 1.4054 0.0364 1.0352 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 357: 92.1834 -5.8818 -2.1457 -4.2525 -0.9334 0.2198 0.0349 3.5894 1.0588 2.7852 0.1449 0.1706 1.4058 0.0364 1.0354 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 358: 92.1834 -5.8808 -2.1459 -4.2531 -0.9334 0.2197 0.0348 3.5861 1.0600 2.7891 0.1449 0.1701 1.4062 0.0364 1.0361 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 359: 92.1833 -5.8799 -2.1459 -4.2533 -0.9333 0.2197 0.0350 3.5822 1.0607 2.7903 0.1448 0.1696 1.4063 0.0364 1.0360 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 360: 92.1831 -5.8792 -2.1460 -4.2534 -0.9332 0.2196 0.0351 3.5787 1.0613 2.7914 0.1446 0.1691 1.4065 0.0364 1.0361 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 361: 92.1831 -5.8785 -2.1460 -4.2542 -0.9331 0.2196 0.0351 3.5771 1.0620 2.7969 0.1445 0.1688 1.4072 0.0364 1.0366 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 362: 92.1832 -5.8780 -2.1462 -4.2547 -0.9331 0.2195 0.0351 3.5750 1.0625 2.8017 0.1443 0.1683 1.4079 0.0363 1.0369 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 363: 92.1830 -5.8788 -2.1464 -4.2551 -0.9331 0.2192 0.0351 3.5785 1.0630 2.8057 0.1443 0.1677 1.4081 0.0363 1.0377 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 364: 92.1829 -5.8778 -2.1466 -4.2554 -0.9332 0.2193 0.0350 3.5747 1.0634 2.8092 0.1443 0.1672 1.4084 0.0363 1.0386 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 365: 92.1830 -5.8782 -2.1466 -4.2558 -0.9332 0.2192 0.0350 3.5771 1.0638 2.8135 0.1443 0.1667 1.4086 0.0363 1.0385 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 366: 92.1830 -5.8795 -2.1465 -4.2564 -0.9332 0.2190 0.0350 3.5838 1.0645 2.8190 0.1444 0.1661 1.4086 0.0363 1.0390 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 367: 92.1826 -5.8801 -2.1465 -4.2569 -0.9333 0.2191 0.0349 3.5867 1.0652 2.8232 0.1445 0.1657 1.4086 0.0362 1.0388 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 368: 92.1824 -5.8799 -2.1465 -4.2571 -0.9333 0.2193 0.0348 3.5859 1.0654 2.8252 0.1445 0.1653 1.4088 0.0362 1.0385 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 369: 92.1822 -5.8803 -2.1467 -4.2572 -0.9333 0.2193 0.0348 3.5846 1.0653 2.8261 0.1444 0.1648 1.4086 0.0362 1.0393 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 370: 92.1820 -5.8802 -2.1469 -4.2575 -0.9333 0.2195 0.0348 3.5822 1.0653 2.8273 0.1444 0.1645 1.4088 0.0362 1.0396 0.0744</span> +<span class="r-out co"><span class="r-pr">#></span> 371: 92.1818 -5.8806 -2.1470 -4.2575 -0.9333 0.2198 0.0348 3.5819 1.0649 2.8277 0.1443 0.1642 1.4091 0.0362 1.0403 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 372: 92.1818 -5.8804 -2.1473 -4.2580 -0.9332 0.2202 0.0348 3.5795 1.0645 2.8300 0.1441 0.1640 1.4096 0.0362 1.0418 0.0743</span> +<span class="r-out co"><span class="r-pr">#></span> 373: 92.1816 -5.8812 -2.1475 -4.2580 -0.9332 0.2203 0.0348 3.5816 1.0644 2.8298 0.1441 0.1639 1.4100 0.0362 1.0439 0.0741</span> +<span class="r-out co"><span class="r-pr">#></span> 374: 92.1815 -5.8817 -2.1477 -4.2578 -0.9333 0.2203 0.0349 3.5819 1.0641 2.8282 0.1440 0.1641 1.4099 0.0362 1.0443 0.0741</span> +<span class="r-out co"><span class="r-pr">#></span> 375: 92.1817 -5.8828 -2.1479 -4.2574 -0.9335 0.2204 0.0351 3.5853 1.0636 2.8267 0.1440 0.1642 1.4100 0.0362 1.0457 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 376: 92.1819 -5.8826 -2.1479 -4.2573 -0.9338 0.2206 0.0353 3.5843 1.0634 2.8246 0.1440 0.1643 1.4100 0.0362 1.0464 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 377: 92.1819 -5.8826 -2.1480 -4.2572 -0.9339 0.2206 0.0354 3.5819 1.0633 2.8225 0.1440 0.1644 1.4097 0.0363 1.0470 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 378: 92.1819 -5.8821 -2.1481 -4.2571 -0.9340 0.2205 0.0355 3.5777 1.0633 2.8206 0.1440 0.1644 1.4093 0.0363 1.0468 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 379: 92.1819 -5.8823 -2.1481 -4.2573 -0.9340 0.2205 0.0356 3.5746 1.0633 2.8201 0.1439 0.1645 1.4092 0.0363 1.0468 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 380: 92.1820 -5.8809 -2.1481 -4.2570 -0.9340 0.2205 0.0356 3.5665 1.0634 2.8178 0.1439 0.1647 1.4093 0.0363 1.0463 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 381: 92.1823 -5.8795 -2.1481 -4.2568 -0.9338 0.2204 0.0357 3.5586 1.0635 2.8170 0.1439 0.1648 1.4095 0.0363 1.0456 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 382: 92.1828 -5.8783 -2.1481 -4.2571 -0.9339 0.2203 0.0357 3.5514 1.0636 2.8183 0.1441 0.1649 1.4093 0.0363 1.0462 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 383: 92.1827 -5.8773 -2.1480 -4.2569 -0.9340 0.2202 0.0357 3.5459 1.0633 2.8173 0.1441 0.1650 1.4094 0.0363 1.0465 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 384: 92.1825 -5.8763 -2.1482 -4.2568 -0.9341 0.2202 0.0357 3.5397 1.0636 2.8165 0.1441 0.1650 1.4094 0.0363 1.0467 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 385: 92.1822 -5.8761 -2.1483 -4.2567 -0.9341 0.2201 0.0357 3.5363 1.0641 2.8160 0.1440 0.1650 1.4094 0.0363 1.0469 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 386: 92.1820 -5.8763 -2.1485 -4.2567 -0.9342 0.2200 0.0356 3.5365 1.0645 2.8157 0.1441 0.1648 1.4092 0.0364 1.0478 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 387: 92.1819 -5.8767 -2.1486 -4.2567 -0.9343 0.2201 0.0358 3.5383 1.0652 2.8156 0.1442 0.1646 1.4090 0.0364 1.0480 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 388: 92.1818 -5.8772 -2.1488 -4.2569 -0.9344 0.2202 0.0359 3.5400 1.0656 2.8153 0.1443 0.1645 1.4086 0.0364 1.0480 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 389: 92.1816 -5.8765 -2.1489 -4.2569 -0.9344 0.2203 0.0359 3.5369 1.0660 2.8145 0.1443 0.1644 1.4083 0.0364 1.0476 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 390: 92.1815 -5.8761 -2.1490 -4.2569 -0.9343 0.2205 0.0359 3.5349 1.0664 2.8136 0.1444 0.1644 1.4080 0.0364 1.0472 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 391: 92.1814 -5.8749 -2.1492 -4.2572 -0.9343 0.2207 0.0359 3.5313 1.0668 2.8153 0.1445 0.1643 1.4077 0.0364 1.0465 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 392: 92.1812 -5.8733 -2.1494 -4.2571 -0.9344 0.2210 0.0359 3.5248 1.0674 2.8141 0.1445 0.1642 1.4073 0.0364 1.0457 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 393: 92.1811 -5.8727 -2.1497 -4.2570 -0.9345 0.2212 0.0359 3.5226 1.0679 2.8127 0.1445 0.1642 1.4071 0.0364 1.0457 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 394: 92.1811 -5.8712 -2.1500 -4.2572 -0.9346 0.2214 0.0360 3.5174 1.0684 2.8132 0.1446 0.1641 1.4067 0.0364 1.0456 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 395: 92.1810 -5.8714 -2.1501 -4.2579 -0.9348 0.2217 0.0361 3.5182 1.0685 2.8171 0.1445 0.1641 1.4065 0.0364 1.0452 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 396: 92.1809 -5.8711 -2.1501 -4.2582 -0.9350 0.2220 0.0363 3.5161 1.0681 2.8184 0.1446 0.1639 1.4063 0.0364 1.0447 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 397: 92.1809 -5.8707 -2.1503 -4.2585 -0.9352 0.2222 0.0363 3.5119 1.0684 2.8197 0.1446 0.1637 1.4065 0.0364 1.0442 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 398: 92.1808 -5.8703 -2.1503 -4.2591 -0.9354 0.2224 0.0363 3.5084 1.0689 2.8218 0.1447 0.1634 1.4064 0.0364 1.0445 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 399: 92.1806 -5.8711 -2.1503 -4.2596 -0.9355 0.2226 0.0364 3.5114 1.0691 2.8234 0.1447 0.1629 1.4061 0.0364 1.0447 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 400: 92.1806 -5.8713 -2.1503 -4.2601 -0.9356 0.2229 0.0366 3.5113 1.0695 2.8253 0.1448 0.1626 1.4059 0.0364 1.0440 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 401: 92.1804 -5.8709 -2.1503 -4.2604 -0.9357 0.2231 0.0367 3.5089 1.0696 2.8266 0.1448 0.1624 1.4058 0.0364 1.0440 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 402: 92.1801 -5.8705 -2.1502 -4.2606 -0.9358 0.2232 0.0368 3.5071 1.0695 2.8268 0.1447 0.1621 1.4060 0.0364 1.0447 0.0740</span> +<span class="r-out co"><span class="r-pr">#></span> 403: 92.1800 -5.8708 -2.1503 -4.2610 -0.9359 0.2234 0.0369 3.5083 1.0697 2.8271 0.1447 0.1618 1.4056 0.0365 1.0448 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 404: 92.1798 -5.8709 -2.1505 -4.2612 -0.9360 0.2237 0.0369 3.5085 1.0699 2.8262 0.1447 0.1616 1.4055 0.0365 1.0449 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 405: 92.1795 -5.8705 -2.1503 -4.2613 -0.9360 0.2239 0.0370 3.5059 1.0698 2.8254 0.1448 0.1615 1.4052 0.0364 1.0449 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 406: 92.1792 -5.8710 -2.1504 -4.2613 -0.9359 0.2243 0.0371 3.5069 1.0696 2.8244 0.1449 0.1614 1.4049 0.0364 1.0447 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 407: 92.1788 -5.8718 -2.1505 -4.2614 -0.9359 0.2243 0.0372 3.5092 1.0697 2.8234 0.1449 0.1614 1.4046 0.0364 1.0448 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 408: 92.1786 -5.8729 -2.1505 -4.2615 -0.9360 0.2245 0.0373 3.5140 1.0699 2.8223 0.1449 0.1612 1.4045 0.0365 1.0455 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 409: 92.1784 -5.8740 -2.1506 -4.2615 -0.9360 0.2246 0.0373 3.5192 1.0700 2.8213 0.1450 0.1610 1.4042 0.0365 1.0462 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 410: 92.1782 -5.8753 -2.1505 -4.2616 -0.9361 0.2246 0.0373 3.5248 1.0705 2.8205 0.1450 0.1607 1.4040 0.0365 1.0465 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 411: 92.1780 -5.8758 -2.1503 -4.2619 -0.9362 0.2247 0.0374 3.5249 1.0707 2.8204 0.1449 0.1605 1.4043 0.0364 1.0467 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 412: 92.1778 -5.8759 -2.1502 -4.2621 -0.9363 0.2248 0.0374 3.5238 1.0707 2.8209 0.1448 0.1602 1.4045 0.0364 1.0466 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 413: 92.1779 -5.8759 -2.1501 -4.2623 -0.9364 0.2249 0.0374 3.5225 1.0711 2.8213 0.1448 0.1600 1.4043 0.0364 1.0460 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 414: 92.1781 -5.8754 -2.1500 -4.2622 -0.9364 0.2250 0.0374 3.5205 1.0710 2.8203 0.1448 0.1599 1.4047 0.0364 1.0456 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 415: 92.1781 -5.8750 -2.1499 -4.2623 -0.9363 0.2251 0.0374 3.5187 1.0709 2.8190 0.1448 0.1598 1.4050 0.0364 1.0448 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 416: 92.1783 -5.8747 -2.1500 -4.2624 -0.9363 0.2252 0.0375 3.5216 1.0708 2.8187 0.1448 0.1598 1.4052 0.0364 1.0440 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 417: 92.1783 -5.8738 -2.1500 -4.2625 -0.9362 0.2252 0.0375 3.5219 1.0712 2.8188 0.1447 0.1597 1.4055 0.0364 1.0438 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 418: 92.1784 -5.8735 -2.1501 -4.2627 -0.9360 0.2254 0.0375 3.5222 1.0715 2.8193 0.1448 0.1596 1.4057 0.0364 1.0438 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 419: 92.1784 -5.8725 -2.1501 -4.2629 -0.9358 0.2255 0.0376 3.5190 1.0719 2.8202 0.1447 0.1594 1.4060 0.0364 1.0436 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 420: 92.1785 -5.8713 -2.1500 -4.2633 -0.9357 0.2256 0.0377 3.5152 1.0723 2.8213 0.1447 0.1592 1.4065 0.0364 1.0439 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 421: 92.1786 -5.8697 -2.1500 -4.2639 -0.9355 0.2257 0.0377 3.5100 1.0728 2.8232 0.1448 0.1592 1.4068 0.0364 1.0436 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 422: 92.1787 -5.8683 -2.1502 -4.2645 -0.9352 0.2260 0.0377 3.5051 1.0732 2.8258 0.1448 0.1592 1.4069 0.0364 1.0432 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 423: 92.1788 -5.8667 -2.1504 -4.2653 -0.9350 0.2262 0.0377 3.4992 1.0736 2.8292 0.1448 0.1592 1.4071 0.0364 1.0435 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 424: 92.1789 -5.8659 -2.1505 -4.2661 -0.9349 0.2263 0.0378 3.4972 1.0739 2.8324 0.1448 0.1591 1.4069 0.0364 1.0439 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 425: 92.1788 -5.8649 -2.1505 -4.2669 -0.9349 0.2263 0.0378 3.4947 1.0740 2.8358 0.1448 0.1590 1.4071 0.0364 1.0438 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 426: 92.1788 -5.8643 -2.1506 -4.2677 -0.9348 0.2265 0.0377 3.4922 1.0743 2.8389 0.1448 0.1589 1.4070 0.0365 1.0437 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 427: 92.1785 -5.8637 -2.1506 -4.2683 -0.9347 0.2266 0.0378 3.4895 1.0747 2.8425 0.1448 0.1588 1.4068 0.0365 1.0434 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 428: 92.1783 -5.8627 -2.1507 -4.2689 -0.9347 0.2268 0.0378 3.4870 1.0749 2.8464 0.1447 0.1586 1.4070 0.0365 1.0434 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 429: 92.1782 -5.8617 -2.1509 -4.2696 -0.9347 0.2271 0.0379 3.4845 1.0752 2.8500 0.1446 0.1584 1.4072 0.0365 1.0439 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 430: 92.1783 -5.8608 -2.1510 -4.2701 -0.9347 0.2274 0.0379 3.4830 1.0755 2.8526 0.1446 0.1582 1.4075 0.0365 1.0443 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 431: 92.1784 -5.8606 -2.1511 -4.2704 -0.9348 0.2275 0.0379 3.4825 1.0757 2.8532 0.1446 0.1580 1.4076 0.0365 1.0439 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 432: 92.1784 -5.8610 -2.1512 -4.2707 -0.9350 0.2275 0.0378 3.4833 1.0761 2.8539 0.1447 0.1578 1.4079 0.0365 1.0443 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 433: 92.1783 -5.8618 -2.1512 -4.2711 -0.9351 0.2276 0.0378 3.4867 1.0768 2.8554 0.1447 0.1577 1.4078 0.0366 1.0440 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 434: 92.1784 -5.8612 -2.1513 -4.2714 -0.9350 0.2278 0.0378 3.4858 1.0774 2.8564 0.1448 0.1577 1.4074 0.0365 1.0430 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 435: 92.1783 -5.8610 -2.1513 -4.2718 -0.9348 0.2279 0.0377 3.4874 1.0779 2.8581 0.1448 0.1576 1.4072 0.0366 1.0423 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 436: 92.1781 -5.8610 -2.1513 -4.2721 -0.9346 0.2280 0.0376 3.4879 1.0789 2.8598 0.1448 0.1575 1.4070 0.0365 1.0417 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 437: 92.1781 -5.8610 -2.1511 -4.2726 -0.9345 0.2279 0.0376 3.4886 1.0794 2.8618 0.1449 0.1574 1.4071 0.0365 1.0417 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 438: 92.1781 -5.8609 -2.1510 -4.2730 -0.9345 0.2280 0.0375 3.4893 1.0797 2.8641 0.1449 0.1573 1.4075 0.0365 1.0420 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 439: 92.1781 -5.8608 -2.1509 -4.2734 -0.9343 0.2280 0.0374 3.4894 1.0803 2.8659 0.1449 0.1573 1.4076 0.0365 1.0421 0.0739</span> +<span class="r-out co"><span class="r-pr">#></span> 440: 92.1780 -5.8603 -2.1510 -4.2737 -0.9343 0.2279 0.0374 3.4885 1.0808 2.8674 0.1448 0.1573 1.4079 0.0365 1.0430 0.0738</span> +<span class="r-out co"><span class="r-pr">#></span> 441: 92.1779 -5.8600 -2.1510 -4.2738 -0.9342 0.2279 0.0373 3.4899 1.0811 2.8686 0.1447 0.1574 1.4086 0.0365 1.0445 0.0737</span> +<span class="r-out co"><span class="r-pr">#></span> 442: 92.1779 -5.8600 -2.1509 -4.2737 -0.9343 0.2278 0.0372 3.4925 1.0814 2.8691 0.1447 0.1575 1.4088 0.0365 1.0451 0.0737</span> +<span class="r-out co"><span class="r-pr">#></span> 443: 92.1780 -5.8598 -2.1509 -4.2739 -0.9341 0.2278 0.0372 3.4949 1.0819 2.8705 0.1447 0.1576 1.4092 0.0365 1.0453 0.0737</span> +<span class="r-out co"><span class="r-pr">#></span> 444: 92.1779 -5.8593 -2.1510 -4.2742 -0.9340 0.2277 0.0371 3.4951 1.0824 2.8717 0.1447 0.1576 1.4096 0.0365 1.0455 0.0737</span> +<span class="r-out co"><span class="r-pr">#></span> 445: 92.1777 -5.8593 -2.1511 -4.2744 -0.9338 0.2275 0.0371 3.4999 1.0828 2.8729 0.1448 0.1576 1.4100 0.0365 1.0461 0.0736</span> +<span class="r-out co"><span class="r-pr">#></span> 446: 92.1774 -5.8600 -2.1511 -4.2748 -0.9338 0.2274 0.0372 3.5051 1.0837 2.8747 0.1449 0.1576 1.4099 0.0365 1.0464 0.0736</span> +<span class="r-out co"><span class="r-pr">#></span> 447: 92.1771 -5.8604 -2.1512 -4.2751 -0.9338 0.2273 0.0373 3.5087 1.0844 2.8758 0.1449 0.1575 1.4097 0.0365 1.0467 0.0736</span> +<span class="r-out co"><span class="r-pr">#></span> 448: 92.1769 -5.8607 -2.1513 -4.2756 -0.9336 0.2272 0.0374 3.5124 1.0849 2.8778 0.1449 0.1575 1.4098 0.0365 1.0470 0.0735</span> +<span class="r-out co"><span class="r-pr">#></span> 449: 92.1768 -5.8611 -2.1515 -4.2759 -0.9337 0.2270 0.0374 3.5165 1.0853 2.8789 0.1449 0.1575 1.4101 0.0365 1.0473 0.0735</span> +<span class="r-out co"><span class="r-pr">#></span> 450: 92.1766 -5.8611 -2.1515 -4.2762 -0.9337 0.2269 0.0374 3.5158 1.0859 2.8800 0.1448 0.1576 1.4102 0.0365 1.0474 0.0735</span> +<span class="r-out co"><span class="r-pr">#></span> 451: 92.1762 -5.8615 -2.1514 -4.2765 -0.9337 0.2267 0.0374 3.5202 1.0866 2.8812 0.1447 0.1576 1.4104 0.0365 1.0477 0.0735</span> +<span class="r-out co"><span class="r-pr">#></span> 452: 92.1761 -5.8622 -2.1514 -4.2767 -0.9337 0.2264 0.0374 3.5232 1.0871 2.8824 0.1447 0.1576 1.4103 0.0365 1.0479 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 453: 92.1760 -5.8621 -2.1514 -4.2776 -0.9336 0.2261 0.0373 3.5247 1.0878 2.8901 0.1447 0.1576 1.4103 0.0365 1.0480 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 454: 92.1759 -5.8611 -2.1513 -4.2781 -0.9335 0.2259 0.0373 3.5206 1.0882 2.8939 0.1448 0.1575 1.4104 0.0365 1.0483 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 455: 92.1758 -5.8599 -2.1513 -4.2788 -0.9336 0.2258 0.0372 3.5151 1.0887 2.9010 0.1448 0.1575 1.4104 0.0365 1.0485 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 456: 92.1760 -5.8583 -2.1512 -4.2797 -0.9335 0.2258 0.0372 3.5086 1.0892 2.9081 0.1448 0.1574 1.4105 0.0365 1.0483 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 457: 92.1761 -5.8575 -2.1513 -4.2804 -0.9334 0.2257 0.0371 3.5041 1.0896 2.9144 0.1449 0.1574 1.4103 0.0365 1.0480 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 458: 92.1763 -5.8569 -2.1512 -4.2813 -0.9334 0.2257 0.0370 3.5014 1.0901 2.9227 0.1449 0.1574 1.4102 0.0365 1.0476 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 459: 92.1763 -5.8565 -2.1512 -4.2816 -0.9334 0.2256 0.0370 3.4991 1.0908 2.9248 0.1449 0.1573 1.4100 0.0365 1.0471 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 460: 92.1764 -5.8557 -2.1513 -4.2818 -0.9333 0.2256 0.0370 3.4957 1.0915 2.9258 0.1449 0.1572 1.4097 0.0365 1.0466 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 461: 92.1765 -5.8550 -2.1515 -4.2822 -0.9333 0.2255 0.0370 3.4923 1.0921 2.9296 0.1449 0.1571 1.4097 0.0365 1.0464 0.0734</span> +<span class="r-out co"><span class="r-pr">#></span> 462: 92.1764 -5.8546 -2.1517 -4.2824 -0.9333 0.2256 0.0370 3.4897 1.0925 2.9319 0.1448 0.1569 1.4093 0.0365 1.0463 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 463: 92.1763 -5.8539 -2.1519 -4.2830 -0.9333 0.2256 0.0369 3.4863 1.0928 2.9373 0.1449 0.1568 1.4093 0.0366 1.0463 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 464: 92.1763 -5.8532 -2.1520 -4.2833 -0.9333 0.2257 0.0370 3.4825 1.0933 2.9405 0.1448 0.1567 1.4093 0.0366 1.0462 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 465: 92.1762 -5.8528 -2.1521 -4.2837 -0.9335 0.2257 0.0370 3.4795 1.0938 2.9433 0.1448 0.1567 1.4093 0.0366 1.0464 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 466: 92.1762 -5.8530 -2.1523 -4.2840 -0.9336 0.2256 0.0370 3.4780 1.0943 2.9462 0.1448 0.1566 1.4089 0.0366 1.0466 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 467: 92.1764 -5.8529 -2.1524 -4.2846 -0.9337 0.2256 0.0371 3.4751 1.0948 2.9506 0.1447 0.1565 1.4087 0.0366 1.0465 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 468: 92.1765 -5.8531 -2.1525 -4.2849 -0.9337 0.2255 0.0371 3.4734 1.0952 2.9523 0.1447 0.1563 1.4087 0.0366 1.0465 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 469: 92.1767 -5.8533 -2.1525 -4.2853 -0.9337 0.2254 0.0372 3.4754 1.0958 2.9540 0.1447 0.1561 1.4090 0.0366 1.0472 0.0733</span> +<span class="r-out co"><span class="r-pr">#></span> 470: 92.1767 -5.8536 -2.1525 -4.2858 -0.9338 0.2254 0.0373 3.4780 1.0965 2.9571 0.1448 0.1559 1.4094 0.0366 1.0478 0.0732</span> +<span class="r-out co"><span class="r-pr">#></span> 471: 92.1767 -5.8540 -2.1525 -4.2864 -0.9338 0.2254 0.0373 3.4812 1.0970 2.9606 0.1447 0.1558 1.4099 0.0366 1.0482 0.0732</span> +<span class="r-out co"><span class="r-pr">#></span> 472: 92.1766 -5.8547 -2.1526 -4.2871 -0.9339 0.2255 0.0373 3.4844 1.0975 2.9645 0.1446 0.1556 1.4101 0.0366 1.0482 0.0732</span> +<span class="r-out co"><span class="r-pr">#></span> 473: 92.1764 -5.8549 -2.1527 -4.2875 -0.9339 0.2255 0.0373 3.4848 1.0977 2.9672 0.1446 0.1554 1.4100 0.0366 1.0482 0.0732</span> +<span class="r-out co"><span class="r-pr">#></span> 474: 92.1762 -5.8553 -2.1528 -4.2880 -0.9338 0.2256 0.0373 3.4855 1.0979 2.9700 0.1445 0.1552 1.4104 0.0366 1.0484 0.0732</span> +<span class="r-out co"><span class="r-pr">#></span> 475: 92.1763 -5.8561 -2.1530 -4.2884 -0.9338 0.2256 0.0374 3.4885 1.0981 2.9726 0.1445 0.1549 1.4103 0.0366 1.0484 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 476: 92.1763 -5.8564 -2.1530 -4.2885 -0.9339 0.2258 0.0374 3.4914 1.0983 2.9734 0.1444 0.1548 1.4106 0.0366 1.0484 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 477: 92.1763 -5.8565 -2.1531 -4.2888 -0.9340 0.2259 0.0373 3.4941 1.0985 2.9755 0.1443 0.1546 1.4108 0.0366 1.0487 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 478: 92.1763 -5.8576 -2.1532 -4.2889 -0.9340 0.2258 0.0373 3.4995 1.0987 2.9772 0.1442 0.1544 1.4111 0.0366 1.0490 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 479: 92.1765 -5.8593 -2.1533 -4.2890 -0.9342 0.2259 0.0372 3.5086 1.0990 2.9787 0.1442 0.1544 1.4113 0.0366 1.0495 0.0731</span> +<span class="r-out co"><span class="r-pr">#></span> 480: 92.1766 -5.8613 -2.1535 -4.2892 -0.9342 0.2260 0.0372 3.5233 1.0991 2.9800 0.1442 0.1543 1.4116 0.0367 1.0496 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 481: 92.1768 -5.8624 -2.1536 -4.2894 -0.9341 0.2260 0.0371 3.5309 1.0993 2.9820 0.1442 0.1542 1.4117 0.0367 1.0497 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 482: 92.1766 -5.8634 -2.1537 -4.2896 -0.9341 0.2260 0.0371 3.5393 1.0995 2.9833 0.1443 0.1542 1.4116 0.0367 1.0496 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 483: 92.1762 -5.8645 -2.1538 -4.2896 -0.9340 0.2260 0.0372 3.5472 1.0997 2.9840 0.1443 0.1542 1.4115 0.0367 1.0498 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 484: 92.1757 -5.8648 -2.1538 -4.2896 -0.9340 0.2261 0.0373 3.5508 1.0998 2.9843 0.1445 0.1542 1.4115 0.0366 1.0498 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 485: 92.1752 -5.8648 -2.1539 -4.2896 -0.9340 0.2262 0.0374 3.5516 1.1000 2.9846 0.1445 0.1542 1.4115 0.0366 1.0497 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 486: 92.1747 -5.8649 -2.1539 -4.2897 -0.9340 0.2262 0.0375 3.5517 1.1003 2.9856 0.1446 0.1541 1.4113 0.0366 1.0498 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 487: 92.1743 -5.8649 -2.1539 -4.2896 -0.9340 0.2262 0.0376 3.5502 1.1006 2.9856 0.1447 0.1539 1.4110 0.0367 1.0498 0.0730</span> +<span class="r-out co"><span class="r-pr">#></span> 488: 92.1739 -5.8645 -2.1540 -4.2893 -0.9340 0.2261 0.0377 3.5475 1.1008 2.9848 0.1447 0.1537 1.4106 0.0367 1.0497 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 489: 92.1736 -5.8640 -2.1539 -4.2892 -0.9340 0.2260 0.0376 3.5445 1.1011 2.9844 0.1448 0.1536 1.4105 0.0367 1.0496 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 490: 92.1736 -5.8631 -2.1539 -4.2889 -0.9340 0.2260 0.0376 3.5402 1.1014 2.9835 0.1448 0.1534 1.4103 0.0366 1.0496 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 491: 92.1735 -5.8617 -2.1539 -4.2887 -0.9339 0.2260 0.0375 3.5343 1.1016 2.9825 0.1449 0.1532 1.4103 0.0366 1.0497 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 492: 92.1736 -5.8609 -2.1539 -4.2884 -0.9339 0.2259 0.0375 3.5298 1.1017 2.9816 0.1449 0.1530 1.4101 0.0367 1.0499 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 493: 92.1737 -5.8605 -2.1539 -4.2882 -0.9339 0.2260 0.0375 3.5266 1.1018 2.9807 0.1450 0.1529 1.4098 0.0367 1.0496 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 494: 92.1739 -5.8609 -2.1539 -4.2881 -0.9340 0.2261 0.0375 3.5273 1.1018 2.9802 0.1450 0.1528 1.4097 0.0367 1.0495 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 495: 92.1741 -5.8614 -2.1540 -4.2880 -0.9340 0.2262 0.0376 3.5290 1.1019 2.9797 0.1450 0.1526 1.4096 0.0367 1.0492 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 496: 92.1742 -5.8623 -2.1540 -4.2879 -0.9341 0.2262 0.0376 3.5348 1.1020 2.9791 0.1449 0.1525 1.4096 0.0367 1.0491 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 497: 92.1742 -5.8634 -2.1541 -4.2879 -0.9341 0.2264 0.0377 3.5402 1.1020 2.9789 0.1449 0.1524 1.4097 0.0367 1.0493 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 498: 92.1744 -5.8637 -2.1543 -4.2879 -0.9341 0.2266 0.0377 3.5406 1.1019 2.9787 0.1449 0.1524 1.4096 0.0367 1.0496 0.0729</span> +<span class="r-out co"><span class="r-pr">#></span> 499: 92.1744 -5.8635 -2.1544 -4.2880 -0.9341 0.2268 0.0376 3.5400 1.1019 2.9789 0.1450 0.1523 1.4095 0.0367 1.0500 0.0728</span> +<span class="r-out co"><span class="r-pr">#></span> 500: 92.1744 -5.8628 -2.1545 -4.2882 -0.9341 0.2270 0.0377 3.5381 1.1020 2.9795 0.1450 0.1522 1.4096 0.0367 1.0503 0.0728</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-in"><span class="va">f_nlmixr_dfop_sfo_focei_obs_tc</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_tc</span><span class="op">[</span><span class="st">"DFOP-SFO"</span>, <span class="op">]</span>, est <span class="op">=</span> <span class="st">"focei"</span>,</span> +<span class="r-in"> error_model <span class="op">=</span> <span class="st">"obs_tc"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="font-weight: bold;">Key:</span> U: Unscaled Parameters; X: Back-transformed parameters; G: Gill difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> F: Forward difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> C: Central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> M: Mixed forward and central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> Unscaled parameters for Omegas=chol(solve(omega));</span> +<span class="r-out co"><span class="r-pr">#></span> Diagonals are transformed, as specified by foceiControl(diagXform=)</span> +<span class="r-out co"><span class="r-pr">#></span> |-----+---------------+-----------+-----------+-----------+-----------|</span> +<span class="r-out co"><span class="r-pr">#></span> | #| Objective Fun | parent_0 | log_k_A1 |f_parent_qlogis | log_k1 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| log_k2 | g_qlogis |sigma_low_parent |rsd_high_parent |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................|sigma_low_A1 |rsd_high_A1 | o1 | o2 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| o3 | o4 | o5 | o6 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 1</span>| 495.48573 | 1.000 | -1.000 | -0.9104 | -0.9376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9875 | -0.8823 | -0.8746 | -0.8907 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8746 | -0.8907 | -0.8767 | -0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8673 | -0.8720 | -0.8739 | -0.8666 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 495.48573 | 91.00 | -5.200 | -0.8900 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.600 | 0.4600 | 0.8300 | 0.05800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8300 | 0.05800 | 0.7311 | 0.9036 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.183 | 0.9554 | 0.8633 | 1.214 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 495.48573</span> | 91.00 | 0.005517 | 0.2911 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01005 | 0.6130 | 0.8300 | 0.05800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8300 | 0.05800 | 0.7311 | 0.9036 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.183 | 0.9554 | 0.8633 | 1.214 |</span> +<span class="r-out co"><span class="r-pr">#></span> | G| Gill Diff. | -0.9648 | 2.223 | -0.3153 | -0.01817 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3350 | 0.6789 | -23.42 | -17.64 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -5.440 | -1.950 | 0.9642 | 9.851 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -11.94 | -1.319 | 8.578 | -12.45 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 2</span>| 481.75012 | 1.026 | -1.060 | -0.9019 | -0.9371 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9785 | -0.9007 | -0.2420 | -0.4142 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7277 | -0.8380 | -0.9027 | -1.139 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5448 | -0.8364 | -1.106 | -0.5303 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 481.75012 | 93.37 | -5.260 | -0.8824 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.591 | 0.4516 | 1.093 | 0.07182 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8910 | 0.05953 | 0.7121 | 0.6631 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.565 | 0.9895 | 0.6633 | 1.623 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 481.75012</span> | 93.37 | 0.005195 | 0.2927 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01014 | 0.6110 | 1.093 | 0.07182 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8910 | 0.05953 | 0.7121 | 0.6631 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.565 | 0.9895 | 0.6633 | 1.623 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 152.5 | 1.317 | 3.315 | -0.1772 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3391 | 0.1426 | -4.513 | 6.696 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.211 | 0.7988 | 0.6299 | -5.324 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009964 | 3.044 | -5.727 | -6.694 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 3</span>| 3004.9713 | 0.2745 | -1.093 | -0.9147 | -0.9360 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9762 | -0.9095 | 0.05941 | -0.2377 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6690 | -0.8188 | -0.9174 | -1.204 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4027 | -0.8359 | -1.205 | -0.3486 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 3004.9713 | 24.98 | -5.293 | -0.8938 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.589 | 0.4475 | 1.218 | 0.07694 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9154 | 0.06008 | 0.7014 | 0.6043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.733 | 0.9899 | 0.5774 | 1.843 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 3004.9713</span> | 24.98 | 0.005026 | 0.2903 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01017 | 0.6100 | 1.218 | 0.07694 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9154 | 0.06008 | 0.7014 | 0.6043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.733 | 0.9899 | 0.5774 | 1.843 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 4</span>| 491.68825 | 0.9393 | -1.061 | -0.9038 | -0.9370 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9787 | -0.9008 | -0.2394 | -0.4180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7284 | -0.8385 | -0.9031 | -1.136 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5448 | -0.8381 | -1.102 | -0.5265 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 491.68825 | 85.47 | -5.261 | -0.8841 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.591 | 0.4515 | 1.094 | 0.07171 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8907 | 0.05951 | 0.7118 | 0.6659 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.565 | 0.9878 | 0.6661 | 1.627 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 491.68825</span> | 85.47 | 0.005191 | 0.2923 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01014 | 0.6110 | 1.094 | 0.07171 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8907 | 0.05951 | 0.7118 | 0.6659 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.565 | 0.9878 | 0.6661 | 1.627 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 5</span>| 479.72282 | 1.001 | -1.060 | -0.9024 | -0.9371 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9785 | -0.9007 | -0.2413 | -0.4153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7279 | -0.8381 | -0.9028 | -1.138 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5448 | -0.8369 | -1.105 | -0.5292 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.72282 | 91.11 | -5.260 | -0.8829 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.591 | 0.4516 | 1.093 | 0.07179 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8909 | 0.05952 | 0.7120 | 0.6639 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.565 | 0.9890 | 0.6641 | 1.624 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.72282</span> | 91.11 | 0.005194 | 0.2926 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01014 | 0.6110 | 1.093 | 0.07179 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8909 | 0.05952 | 0.7120 | 0.6639 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.565 | 0.9890 | 0.6641 | 1.624 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 6.589 | 1.222 | 0.9137 | 0.1103 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3993 | 0.5206 | -3.904 | 6.654 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9090 | 1.134 | -1.839 | -6.108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.622 | 4.007 | -4.921 | -6.374 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 6</span>| 479.56384 | 0.9950 | -1.061 | -0.9037 | -0.9373 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9792 | -0.9012 | -0.2438 | -0.4298 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7309 | -0.8403 | -0.9001 | -1.126 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5509 | -0.8426 | -1.095 | -0.5241 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.56384 | 90.55 | -5.261 | -0.8840 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.592 | 0.4513 | 1.092 | 0.07137 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8897 | 0.05946 | 0.7140 | 0.6748 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.558 | 0.9836 | 0.6729 | 1.630 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.56384</span> | 90.55 | 0.005189 | 0.2923 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01014 | 0.6110 | 1.092 | 0.07137 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8897 | 0.05946 | 0.7140 | 0.6748 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.558 | 0.9836 | 0.6729 | 1.630 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -31.71 | 1.225 | 0.1963 | 0.1681 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4113 | 0.6853 | -4.208 | 6.141 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7033 | 1.163 | -2.029 | -4.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.106 | 3.494 | -3.921 | -6.098 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 7</span>| 479.23599 | 1.003 | -1.063 | -0.9048 | -0.9375 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9799 | -0.9023 | -0.2352 | -0.4403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7320 | -0.8422 | -0.8974 | -1.117 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5472 | -0.8484 | -1.086 | -0.5115 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.23599 | 91.29 | -5.263 | -0.8850 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.592 | 0.4508 | 1.095 | 0.07106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8892 | 0.05941 | 0.7160 | 0.6828 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.562 | 0.9781 | 0.6800 | 1.645 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.23599</span> | 91.29 | 0.005177 | 0.2921 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01013 | 0.6108 | 1.095 | 0.07106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8892 | 0.05941 | 0.7160 | 0.6828 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.562 | 0.9781 | 0.6800 | 1.645 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 18.36 | 1.286 | 0.8956 | 0.06941 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3942 | 0.6495 | -3.460 | 6.349 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7828 | 0.9998 | -1.947 | -2.931 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1591 | 2.144 | -3.375 | -5.909 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 8</span>| 479.05200 | 0.9982 | -1.066 | -0.9056 | -0.9376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9803 | -0.9037 | -0.2181 | -0.4407 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7304 | -0.8427 | -0.8951 | -1.119 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5384 | -0.8504 | -1.087 | -0.4972 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.052 | 90.84 | -5.266 | -0.8857 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.593 | 0.4502 | 1.102 | 0.07105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8899 | 0.05939 | 0.7177 | 0.6818 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.572 | 0.9761 | 0.6797 | 1.663 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.052</span> | 90.84 | 0.005162 | 0.2920 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01012 | 0.6107 | 1.102 | 0.07105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8899 | 0.05939 | 0.7177 | 0.6818 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.572 | 0.9761 | 0.6797 | 1.663 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 9</span>| 478.91507 | 0.9977 | -1.070 | -0.9061 | -0.9377 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9807 | -0.9051 | -0.2002 | -0.4395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7284 | -0.8431 | -0.8930 | -1.121 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5287 | -0.8520 | -1.088 | -0.4828 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.91507 | 90.79 | -5.270 | -0.8862 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.593 | 0.4495 | 1.110 | 0.07109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8907 | 0.05938 | 0.7192 | 0.6799 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.584 | 0.9745 | 0.6785 | 1.680 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.91507</span> | 90.79 | 0.005146 | 0.2919 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01012 | 0.6105 | 1.110 | 0.07109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8907 | 0.05938 | 0.7192 | 0.6799 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.584 | 0.9745 | 0.6785 | 1.680 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 10</span>| 478.54700 | 0.9959 | -1.080 | -0.9081 | -0.9381 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9820 | -0.9099 | -0.1391 | -0.4353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7215 | -0.8442 | -0.8862 | -1.128 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4957 | -0.8577 | -1.093 | -0.4342 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.547 | 90.63 | -5.280 | -0.8880 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.594 | 0.4473 | 1.135 | 0.07121 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8936 | 0.05935 | 0.7242 | 0.6734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.623 | 0.9691 | 0.6746 | 1.739 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.547</span> | 90.63 | 0.005094 | 0.2915 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01011 | 0.6100 | 1.135 | 0.07121 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8936 | 0.05935 | 0.7242 | 0.6734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.623 | 0.9691 | 0.6746 | 1.739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 11</span>| 478.24707 | 0.9926 | -1.098 | -0.9118 | -0.9388 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9843 | -0.9186 | -0.02735 | -0.4276 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7088 | -0.8464 | -0.8736 | -1.141 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4354 | -0.8680 | -1.101 | -0.3451 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.24707 | 90.33 | -5.298 | -0.8913 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.597 | 0.4433 | 1.182 | 0.07143 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8988 | 0.05929 | 0.7334 | 0.6616 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.694 | 0.9593 | 0.6674 | 1.848 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.24707</span> | 90.33 | 0.004999 | 0.2909 | 0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01008 | 0.6090 | 1.182 | 0.07143 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8988 | 0.05929 | 0.7334 | 0.6616 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.694 | 0.9593 | 0.6674 | 1.848 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -54.86 | 1.159 | -0.2545 | 0.1198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4779 | 1.320 | -1.627 | 7.719 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.488 | 1.194 | -2.008 | -4.434 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.563 | 0.8010 | -2.393 | -3.495 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 12</span>| 475.90466 | 1.002 | -1.127 | -0.9233 | -0.9398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9978 | -0.9482 | -0.05448 | -0.6822 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7579 | -0.8801 | -0.8190 | -1.095 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4550 | -0.8498 | -1.031 | -0.2699 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.90466 | 91.18 | -5.327 | -0.9014 | -2.202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.610 | 0.4297 | 1.170 | 0.06405 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8785 | 0.05831 | 0.7733 | 0.7032 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.671 | 0.9767 | 0.7277 | 1.939 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.90466</span> | 91.18 | 0.004860 | 0.2888 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009950 | 0.6058 | 1.170 | 0.06405 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8785 | 0.05831 | 0.7733 | 0.7032 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.671 | 0.9767 | 0.7277 | 1.939 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.773 | 1.281 | 0.05418 | -0.06269 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4104 | 1.812 | -4.981 | 3.640 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.08126 | 0.09477 | -1.092 | -2.966 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 5.262 | 2.712 | 3.245 | -2.012 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 13</span>| 477.06760 | 1.030 | -1.176 | -0.9281 | -0.9377 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.013 | -1.011 | 0.09564 | -0.8420 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7668 | -0.8907 | -0.7738 | -1.073 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5619 | -0.8693 | -1.126 | -0.1773 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 477.0676 | 93.71 | -5.376 | -0.9057 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.625 | 0.4008 | 1.233 | 0.05941 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8748 | 0.05800 | 0.8064 | 0.7234 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.545 | 0.9581 | 0.6461 | 2.051 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 477.0676</span> | 93.71 | 0.004627 | 0.2879 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009799 | 0.5989 | 1.233 | 0.05941 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8748 | 0.05800 | 0.8064 | 0.7234 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.545 | 0.9581 | 0.6461 | 2.051 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 14</span>| 477.20174 | 1.026 | -1.143 | -0.9246 | -0.9391 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.003 | -0.9695 | -0.001726 | -0.7335 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7599 | -0.8831 | -0.8043 | -1.080 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4976 | -0.8627 | -1.065 | -0.2404 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 477.20174 | 93.37 | -5.343 | -0.9027 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.615 | 0.4199 | 1.192 | 0.06256 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8776 | 0.05822 | 0.7840 | 0.7162 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.621 | 0.9644 | 0.6988 | 1.975 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 477.20174</span> | 93.37 | 0.004782 | 0.2885 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009899 | 0.6035 | 1.192 | 0.06256 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8776 | 0.05822 | 0.7840 | 0.7162 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.621 | 0.9644 | 0.6988 | 1.975 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 15</span>| 476.22973 | 1.014 | -1.129 | -0.9234 | -0.9397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9986 | -0.9521 | -0.04396 | -0.6899 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7577 | -0.8803 | -0.8167 | -1.089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4661 | -0.8555 | -1.038 | -0.2656 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.22973 | 92.29 | -5.329 | -0.9015 | -2.202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.611 | 0.4279 | 1.175 | 0.06382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8785 | 0.05830 | 0.7750 | 0.7089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.658 | 0.9712 | 0.7218 | 1.944 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.22973</span> | 92.29 | 0.004847 | 0.2887 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009941 | 0.6054 | 1.175 | 0.06382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8785 | 0.05830 | 0.7750 | 0.7089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.658 | 0.9712 | 0.7218 | 1.944 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 16</span>| 475.87776 | 1.005 | -1.127 | -0.9233 | -0.9398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9980 | -0.9491 | -0.05201 | -0.6840 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7578 | -0.8802 | -0.8184 | -1.093 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4576 | -0.8511 | -1.033 | -0.2689 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.87776 | 91.44 | -5.327 | -0.9015 | -2.202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.610 | 0.4293 | 1.171 | 0.06399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8785 | 0.05830 | 0.7737 | 0.7045 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.668 | 0.9754 | 0.7263 | 1.940 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.87776</span> | 91.44 | 0.004857 | 0.2887 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009948 | 0.6057 | 1.171 | 0.06399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8785 | 0.05830 | 0.7737 | 0.7045 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.668 | 0.9754 | 0.7263 | 1.940 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 16.12 | 1.298 | 0.4116 | -0.09723 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4002 | 1.728 | -4.991 | 3.781 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06392 | 0.04117 | -1.251 | -0.6787 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 5.079 | 2.620 | 3.013 | -2.074 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 17</span>| 475.82399 | 1.002 | -1.128 | -0.9234 | -0.9397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9982 | -0.9501 | -0.04950 | -0.6866 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7580 | -0.8803 | -0.8177 | -1.093 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4596 | -0.8518 | -1.034 | -0.2675 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.82399 | 91.17 | -5.328 | -0.9016 | -2.202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.611 | 0.4288 | 1.172 | 0.06392 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8784 | 0.05830 | 0.7743 | 0.7045 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.666 | 0.9748 | 0.7251 | 1.942 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.82399</span> | 91.17 | 0.004853 | 0.2887 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009945 | 0.6056 | 1.172 | 0.06392 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8784 | 0.05830 | 0.7743 | 0.7045 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.666 | 0.9748 | 0.7251 | 1.942 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -7.267 | 1.279 | 0.007095 | -0.05940 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4115 | 1.783 | -5.114 | 3.652 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1068 | 0.1083 | -1.295 | -0.9578 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.682 | 2.514 | 3.014 | -2.035 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 18</span>| 475.78862 | 1.005 | -1.129 | -0.9235 | -0.9397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9985 | -0.9512 | -0.04657 | -0.6892 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7580 | -0.8804 | -0.8168 | -1.093 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4611 | -0.8527 | -1.036 | -0.2661 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.78862 | 91.41 | -5.329 | -0.9016 | -2.202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.611 | 0.4283 | 1.174 | 0.06384 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8784 | 0.05830 | 0.7749 | 0.7045 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.664 | 0.9739 | 0.7236 | 1.943 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.78862</span> | 91.41 | 0.004849 | 0.2887 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009942 | 0.6055 | 1.174 | 0.06384 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8784 | 0.05830 | 0.7749 | 0.7045 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.664 | 0.9739 | 0.7236 | 1.943 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 13.19 | 1.292 | 0.3498 | -0.09321 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4023 | 1.703 | -5.372 | 3.699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1234 | 0.05429 | -1.241 | -0.7588 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.815 | 2.436 | 2.783 | -2.083 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 19</span>| 475.73531 | 1.002 | -1.130 | -0.9236 | -0.9397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9987 | -0.9524 | -0.04361 | -0.6921 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7582 | -0.8806 | -0.8159 | -1.094 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4630 | -0.8531 | -1.037 | -0.2646 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.73531 | 91.21 | -5.330 | -0.9018 | -2.202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.611 | 0.4278 | 1.175 | 0.06376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8783 | 0.05829 | 0.7756 | 0.7041 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.662 | 0.9735 | 0.7222 | 1.945 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.73531</span> | 91.21 | 0.004845 | 0.2887 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009940 | 0.6053 | 1.175 | 0.06376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8783 | 0.05829 | 0.7756 | 0.7041 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.662 | 0.9735 | 0.7222 | 1.945 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.312 | 1.277 | 0.06663 | -0.06695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4102 | 1.736 | -5.095 | 3.555 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.08175 | 0.08515 | -1.253 | -0.9364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.836 | 2.452 | 2.739 | -2.058 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 20</span>| 475.69941 | 1.004 | -1.131 | -0.9237 | -0.9396 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9990 | -0.9534 | -0.04063 | -0.6942 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7581 | -0.8807 | -0.8151 | -1.093 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4658 | -0.8545 | -1.039 | -0.2634 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.69941 | 91.39 | -5.331 | -0.9018 | -2.202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.611 | 0.4273 | 1.176 | 0.06370 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8783 | 0.05829 | 0.7761 | 0.7046 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.658 | 0.9722 | 0.7208 | 1.947 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.69941</span> | 91.39 | 0.004841 | 0.2887 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009937 | 0.6052 | 1.176 | 0.06370 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8783 | 0.05829 | 0.7761 | 0.7046 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.658 | 0.9722 | 0.7208 | 1.947 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 11.57 | 1.287 | 0.3079 | -0.08979 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4039 | 1.674 | -5.153 | 3.653 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06063 | 0.04440 | -1.200 | -0.7646 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.452 | 2.339 | 2.552 | -2.095 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 21</span>| 475.66307 | 1.001 | -1.131 | -0.9238 | -0.9396 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9992 | -0.9545 | -0.03780 | -0.6969 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7583 | -0.8808 | -0.8143 | -1.094 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4671 | -0.8550 | -1.041 | -0.2620 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.66307 | 91.11 | -5.331 | -0.9019 | -2.202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.612 | 0.4268 | 1.177 | 0.06362 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8783 | 0.05829 | 0.7767 | 0.7044 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.657 | 0.9717 | 0.7195 | 1.948 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.66307</span> | 91.11 | 0.004837 | 0.2887 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009935 | 0.6051 | 1.177 | 0.06362 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8783 | 0.05829 | 0.7767 | 0.7044 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.657 | 0.9717 | 0.7195 | 1.948 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -12.57 | 1.267 | -0.09715 | -0.05310 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4138 | 1.728 | -5.558 | 3.438 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1081 | 0.1203 | -1.232 | -1.053 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.344 | 2.291 | 2.543 | -2.059 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 22</span>| 475.61346 | 1.003 | -1.132 | -0.9238 | -0.9395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9995 | -0.9557 | -0.03467 | -0.6999 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7585 | -0.8810 | -0.8134 | -1.094 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4680 | -0.8550 | -1.042 | -0.2607 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.61346 | 91.32 | -5.332 | -0.9020 | -2.202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.612 | 0.4262 | 1.179 | 0.06353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8782 | 0.05828 | 0.7774 | 0.7040 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.656 | 0.9717 | 0.7181 | 1.950 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.61346</span> | 91.32 | 0.004833 | 0.2886 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009932 | 0.6050 | 1.179 | 0.06353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8782 | 0.05828 | 0.7774 | 0.7040 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.656 | 0.9717 | 0.7181 | 1.950 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.192 | 1.277 | 0.1967 | -0.08157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4060 | 1.656 | -5.231 | 3.627 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1038 | 0.05786 | -1.199 | -0.8859 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.283 | 2.293 | 2.331 | -2.101 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 23</span>| 475.58436 | 1.001 | -1.133 | -0.9239 | -0.9395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9998 | -0.9568 | -0.03140 | -0.7025 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7585 | -0.8810 | -0.8126 | -1.094 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4692 | -0.8560 | -1.044 | -0.2594 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.58436 | 91.09 | -5.333 | -0.9021 | -2.202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.612 | 0.4257 | 1.180 | 0.06346 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8782 | 0.05828 | 0.7780 | 0.7043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.654 | 0.9707 | 0.7167 | 1.952 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.58436</span> | 91.09 | 0.004829 | 0.2886 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009929 | 0.6049 | 1.180 | 0.06346 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8782 | 0.05828 | 0.7780 | 0.7043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.654 | 0.9707 | 0.7167 | 1.952 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -14.46 | 1.261 | -0.1306 | -0.05131 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4140 | 1.696 | -5.518 | 3.404 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1407 | 0.1181 | -1.199 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.272 | 2.212 | 2.296 | -2.075 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 24</span>| 475.53229 | 1.003 | -1.134 | -0.9240 | -0.9394 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.000 | -0.9581 | -0.02828 | -0.7055 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7587 | -0.8812 | -0.8117 | -1.094 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4701 | -0.8560 | -1.045 | -0.2580 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.53229 | 91.31 | -5.334 | -0.9021 | -2.202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.613 | 0.4251 | 1.181 | 0.06337 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8781 | 0.05828 | 0.7786 | 0.7039 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.653 | 0.9708 | 0.7153 | 1.953 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.53229</span> | 91.31 | 0.004824 | 0.2886 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009926 | 0.6047 | 1.181 | 0.06337 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8781 | 0.05828 | 0.7786 | 0.7039 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.653 | 0.9708 | 0.7153 | 1.953 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.355 | 1.271 | 0.1786 | -0.08149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4055 | 1.621 | -5.117 | 3.557 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1060 | 0.04285 | -0.9518 | -2.902 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.469 | 2.204 | 2.093 | -2.115 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 25</span>| 475.50379 | 1.001 | -1.135 | -0.9241 | -0.9394 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.000 | -0.9591 | -0.02533 | -0.7076 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7587 | -0.8812 | -0.8111 | -1.093 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4726 | -0.8571 | -1.047 | -0.2568 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.50379 | 91.10 | -5.335 | -0.9022 | -2.202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.613 | 0.4247 | 1.182 | 0.06331 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8781 | 0.05828 | 0.7790 | 0.7053 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.650 | 0.9697 | 0.7143 | 1.955 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.50379</span> | 91.10 | 0.004820 | 0.2886 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009924 | 0.6046 | 1.182 | 0.06331 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8781 | 0.05828 | 0.7790 | 0.7053 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.650 | 0.9697 | 0.7143 | 1.955 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -13.73 | 1.259 | -0.1294 | -0.05234 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4131 | 1.659 | -5.626 | 3.356 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1179 | 0.1182 | -1.163 | -0.9759 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.282 | 2.162 | 2.085 | -2.085 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 26</span>| 475.45890 | 1.004 | -1.136 | -0.9240 | -0.9393 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.001 | -0.9602 | -0.02221 | -0.7103 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7588 | -0.8813 | -0.8104 | -1.092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4738 | -0.8571 | -1.048 | -0.2555 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.4589 | 91.37 | -5.336 | -0.9021 | -2.202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.613 | 0.4242 | 1.184 | 0.06323 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8781 | 0.05827 | 0.7796 | 0.7056 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.649 | 0.9697 | 0.7132 | 1.956 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.4589</span> | 91.37 | 0.004816 | 0.2886 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009921 | 0.6045 | 1.184 | 0.06323 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8781 | 0.05827 | 0.7796 | 0.7056 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.649 | 0.9697 | 0.7132 | 1.956 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 9.388 | 1.275 | 0.2447 | -0.08891 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4027 | 1.576 | -4.598 | 3.539 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.08390 | 0.04261 | -0.9004 | -2.725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.305 | 2.111 | 1.882 | -2.135 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 27</span>| 475.41657 | 1.002 | -1.137 | -0.9241 | -0.9392 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.001 | -0.9615 | -0.01910 | -0.7133 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7590 | -0.8814 | -0.8097 | -1.092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4754 | -0.8571 | -1.049 | -0.2540 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.41657 | 91.17 | -5.337 | -0.9022 | -2.202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.613 | 0.4236 | 1.185 | 0.06314 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8780 | 0.05827 | 0.7801 | 0.7060 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.647 | 0.9697 | 0.7121 | 1.958 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.41657</span> | 91.17 | 0.004811 | 0.2886 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009918 | 0.6043 | 1.185 | 0.06314 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8780 | 0.05827 | 0.7801 | 0.7060 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.647 | 0.9697 | 0.7121 | 1.958 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -7.291 | 1.263 | -0.02799 | -0.06240 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4098 | 1.607 | -5.561 | 3.409 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1363 | 0.09124 | -1.126 | -0.9025 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.264 | 2.123 | 1.858 | -2.103 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 28</span>| 475.37603 | 1.004 | -1.138 | -0.9241 | -0.9392 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.001 | -0.9626 | -0.01569 | -0.7160 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7590 | -0.8815 | -0.8090 | -1.092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4775 | -0.8574 | -1.050 | -0.2525 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.37603 | 91.35 | -5.338 | -0.9022 | -2.202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.614 | 0.4231 | 1.186 | 0.06307 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8780 | 0.05827 | 0.7806 | 0.7060 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.645 | 0.9695 | 0.7112 | 1.960 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.37603</span> | 91.35 | 0.004807 | 0.2886 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009915 | 0.6042 | 1.186 | 0.06307 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8780 | 0.05827 | 0.7806 | 0.7060 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.645 | 0.9695 | 0.7112 | 1.960 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 7.976 | 1.271 | 0.2167 | -0.08766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4024 | 1.550 | -5.132 | 3.516 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09627 | 0.04106 | -1.088 | -0.7404 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.103 | 2.126 | 1.707 | -2.133 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 29</span>| 475.34297 | 1.001 | -1.139 | -0.9242 | -0.9391 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.002 | -0.9636 | -0.01242 | -0.7185 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7591 | -0.8816 | -0.8082 | -1.092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4796 | -0.8578 | -1.051 | -0.2511 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.34297 | 91.13 | -5.339 | -0.9023 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.614 | 0.4226 | 1.188 | 0.06299 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8779 | 0.05826 | 0.7812 | 0.7056 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.642 | 0.9691 | 0.7103 | 1.962 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.34297</span> | 91.13 | 0.004803 | 0.2886 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009912 | 0.6041 | 1.188 | 0.06299 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8779 | 0.05826 | 0.7812 | 0.7056 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.642 | 0.9691 | 0.7103 | 1.962 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -11.69 | 1.251 | -0.09758 | -0.05188 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4100 | 1.596 | -5.544 | 3.338 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1288 | 0.09302 | -1.103 | -0.9943 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.044 | 2.113 | 1.726 | -2.096 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 30</span>| 475.29763 | 1.004 | -1.140 | -0.9242 | -0.9391 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.002 | -0.9647 | -0.009016 | -0.7212 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7592 | -0.8817 | -0.8074 | -1.093 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4815 | -0.8578 | -1.052 | -0.2496 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.29763 | 91.33 | -5.340 | -0.9023 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.614 | 0.4221 | 1.189 | 0.06292 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8779 | 0.05826 | 0.7818 | 0.7049 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.640 | 0.9691 | 0.7096 | 1.964 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.29763</span> | 91.33 | 0.004798 | 0.2886 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009909 | 0.6040 | 1.189 | 0.06292 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8779 | 0.05826 | 0.7818 | 0.7049 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.640 | 0.9691 | 0.7096 | 1.964 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.626 | 1.261 | 0.1834 | -0.08674 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4019 | 1.535 | -5.612 | 3.466 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1091 | 0.03444 | -1.082 | -0.8814 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.882 | 2.084 | 1.576 | -2.128 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 31</span>| 475.26968 | 1.001 | -1.140 | -0.9243 | -0.9390 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.002 | -0.9656 | -0.005554 | -0.7235 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7592 | -0.8818 | -0.8067 | -1.093 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4837 | -0.8585 | -1.053 | -0.2482 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.26968 | 91.11 | -5.340 | -0.9024 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.615 | 0.4217 | 1.191 | 0.06285 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8779 | 0.05826 | 0.7823 | 0.7049 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.637 | 0.9684 | 0.7088 | 1.965 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.26968</span> | 91.11 | 0.004794 | 0.2886 | 0.1106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009907 | 0.6039 | 1.191 | 0.06285 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8779 | 0.05826 | 0.7823 | 0.7049 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.637 | 0.9684 | 0.7088 | 1.965 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -13.71 | 1.246 | -0.1255 | -0.05322 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4099 | 1.581 | -5.546 | 3.317 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1509 | 0.1096 | -0.8594 | -3.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.990 | 2.056 | 1.604 | -2.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 32</span>| 475.22190 | 1.004 | -1.141 | -0.9243 | -0.9390 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.002 | -0.9667 | -0.002058 | -0.7261 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7593 | -0.8819 | -0.8061 | -1.093 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4854 | -0.8583 | -1.054 | -0.2469 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.2219 | 91.33 | -5.341 | -0.9024 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.615 | 0.4212 | 1.192 | 0.06277 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05826 | 0.7828 | 0.7049 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.635 | 0.9686 | 0.7081 | 1.967 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.2219</span> | 91.33 | 0.004790 | 0.2886 | 0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009904 | 0.6038 | 1.192 | 0.06277 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05826 | 0.7828 | 0.7049 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.635 | 0.9686 | 0.7081 | 1.967 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.841 | 1.258 | 0.1840 | -0.08823 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4011 | 1.514 | -4.992 | 3.441 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1080 | 0.03852 | -1.043 | -0.8514 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.826 | 2.019 | 1.451 | -2.125 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 33</span>| 475.19540 | 1.001 | -1.142 | -0.9244 | -0.9389 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.003 | -0.9677 | 0.001228 | -0.7286 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7593 | -0.8819 | -0.8054 | -1.093 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4876 | -0.8589 | -1.055 | -0.2455 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.1954 | 91.10 | -5.342 | -0.9025 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.615 | 0.4207 | 1.193 | 0.06270 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05825 | 0.7833 | 0.7050 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.633 | 0.9680 | 0.7073 | 1.969 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.1954</span> | 91.10 | 0.004786 | 0.2885 | 0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009901 | 0.6037 | 1.193 | 0.06270 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05825 | 0.7833 | 0.7050 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.633 | 0.9680 | 0.7073 | 1.969 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -14.17 | 1.239 | -0.1323 | -0.05443 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4093 | 1.561 | -5.475 | 3.262 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1301 | 0.09817 | -1.038 | -1.045 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.818 | 2.054 | 1.474 | -2.085 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 34</span>| 475.14668 | 1.003 | -1.143 | -0.9244 | -0.9388 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.003 | -0.9688 | 0.004635 | -0.7312 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7595 | -0.8820 | -0.8046 | -1.094 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4894 | -0.8588 | -1.055 | -0.2440 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.14668 | 91.31 | -5.343 | -0.9025 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.615 | 0.4202 | 1.195 | 0.06262 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05825 | 0.7838 | 0.7043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.631 | 0.9681 | 0.7066 | 1.970 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.14668</span> | 91.31 | 0.004781 | 0.2885 | 0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009898 | 0.6035 | 1.195 | 0.06262 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05825 | 0.7838 | 0.7043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.631 | 0.9681 | 0.7066 | 1.970 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.838 | 1.251 | 0.1547 | -0.08725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4006 | 1.498 | -4.927 | 3.416 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1219 | 0.06473 | -1.010 | -2.917 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.712 | 2.020 | 1.337 | -2.117 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 35</span>| 475.12366 | 1.001 | -1.144 | -0.9245 | -0.9388 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.003 | -0.9698 | 0.007665 | -0.7333 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7594 | -0.8821 | -0.8040 | -1.092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4916 | -0.8600 | -1.056 | -0.2427 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.12366 | 91.10 | -5.344 | -0.9025 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.616 | 0.4198 | 1.196 | 0.06256 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05825 | 0.7843 | 0.7059 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.628 | 0.9669 | 0.7059 | 1.972 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.12366</span> | 91.10 | 0.004777 | 0.2885 | 0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009896 | 0.6034 | 1.196 | 0.06256 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05825 | 0.7843 | 0.7059 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.628 | 0.9669 | 0.7059 | 1.972 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -14.75 | 1.239 | -0.1466 | -0.05465 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4082 | 1.541 | -5.471 | 3.270 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1342 | 0.09829 | -1.014 | -1.026 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.624 | 1.932 | 1.359 | -2.081 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 36</span>| 475.07465 | 1.004 | -1.145 | -0.9245 | -0.9387 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.003 | -0.9709 | 0.01108 | -0.7360 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7595 | -0.8821 | -0.8033 | -1.092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4933 | -0.8597 | -1.057 | -0.2414 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.07465 | 91.33 | -5.345 | -0.9025 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.616 | 0.4193 | 1.198 | 0.06248 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05825 | 0.7848 | 0.7058 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.626 | 0.9672 | 0.7053 | 1.974 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.07465</span> | 91.33 | 0.004773 | 0.2885 | 0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009893 | 0.6033 | 1.198 | 0.06248 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05825 | 0.7848 | 0.7058 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.626 | 0.9672 | 0.7053 | 1.974 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.021 | 1.249 | 0.1599 | -0.08992 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3985 | 1.471 | -4.995 | 3.410 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1196 | 0.03779 | -0.9990 | -2.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.497 | 1.906 | 1.211 | -2.119 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 37</span>| 475.04940 | 1.001 | -1.146 | -0.9245 | -0.9386 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.004 | -0.9719 | 0.01438 | -0.7384 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7594 | -0.8822 | -0.8026 | -1.091 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4953 | -0.8604 | -1.058 | -0.2400 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.0494 | 91.11 | -5.346 | -0.9026 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.616 | 0.4188 | 1.199 | 0.06242 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05825 | 0.7853 | 0.7070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.623 | 0.9666 | 0.7046 | 1.975 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.0494</span> | 91.11 | 0.004769 | 0.2885 | 0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009890 | 0.6032 | 1.199 | 0.06242 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05825 | 0.7853 | 0.7070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.623 | 0.9666 | 0.7046 | 1.975 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -14.15 | 1.235 | -0.1370 | -0.05688 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4085 | 1.517 | -5.494 | 3.160 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1583 | 0.1112 | -0.7821 | -2.927 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.432 | 1.909 | 1.245 | -2.084 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 38</span>| 475.00092 | 1.004 | -1.147 | -0.9245 | -0.9386 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.004 | -0.9731 | 0.01792 | -0.7411 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7595 | -0.8822 | -0.8020 | -1.090 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4968 | -0.8598 | -1.059 | -0.2387 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.00092 | 91.32 | -5.347 | -0.9025 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.617 | 0.4182 | 1.200 | 0.06234 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05825 | 0.7857 | 0.7077 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.622 | 0.9671 | 0.7039 | 1.977 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.00092</span> | 91.32 | 0.004764 | 0.2885 | 0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009887 | 0.6031 | 1.200 | 0.06234 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05825 | 0.7857 | 0.7077 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.622 | 0.9671 | 0.7039 | 1.977 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.379 | 1.249 | 0.1419 | -0.08698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3989 | 1.449 | -4.966 | 3.395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1055 | 0.03295 | -0.9696 | -0.7580 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.283 | 1.918 | 1.096 | -2.115 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 39</span>| 474.98492 | 1.001 | -1.147 | -0.9246 | -0.9385 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.004 | -0.9740 | 0.02115 | -0.7433 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7595 | -0.8822 | -0.8014 | -1.089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4989 | -0.8610 | -1.059 | -0.2373 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.98492 | 91.07 | -5.347 | -0.9026 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.617 | 0.4178 | 1.202 | 0.06227 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05825 | 0.7862 | 0.7081 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.619 | 0.9660 | 0.7033 | 1.978 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.98492</span> | 91.07 | 0.004760 | 0.2885 | 0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009884 | 0.6030 | 1.202 | 0.06227 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05825 | 0.7862 | 0.7081 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.619 | 0.9660 | 0.7033 | 1.978 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -17.65 | 1.231 | -0.1920 | -0.05242 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4084 | 1.504 | -5.397 | 3.171 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1354 | 0.1061 | -0.9468 | -0.9144 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.271 | 1.859 | 1.156 | -2.067 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 40</span>| 474.93249 | 1.004 | -1.148 | -0.9245 | -0.9384 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.005 | -0.9752 | 0.02452 | -0.7460 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7596 | -0.8823 | -0.8007 | -1.090 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5000 | -0.8607 | -1.060 | -0.2361 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.93249 | 91.32 | -5.348 | -0.9026 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.617 | 0.4173 | 1.203 | 0.06220 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05824 | 0.7867 | 0.7073 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.618 | 0.9663 | 0.7027 | 1.980 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.93249</span> | 91.32 | 0.004755 | 0.2885 | 0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009881 | 0.6028 | 1.203 | 0.06220 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8778 | 0.05824 | 0.7867 | 0.7073 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.618 | 0.9663 | 0.7027 | 1.980 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.492 | 1.243 | 0.1448 | -0.09052 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3963 | 1.427 | -4.973 | 3.376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06414 | 0.02300 | -0.7344 | -2.787 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.083 | 1.834 | 0.9813 | -2.110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 41</span>| 474.90355 | 1.001 | -1.149 | -0.9246 | -0.9383 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.005 | -0.9763 | 0.02806 | -0.7486 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7596 | -0.8823 | -0.8002 | -1.089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5018 | -0.8611 | -1.061 | -0.2347 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.90355 | 91.13 | -5.349 | -0.9026 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.617 | 0.4168 | 1.205 | 0.06212 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7870 | 0.7084 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.616 | 0.9659 | 0.7020 | 1.982 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.90355</span> | 91.13 | 0.004751 | 0.2885 | 0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009878 | 0.6027 | 1.205 | 0.06212 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7870 | 0.7084 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.616 | 0.9659 | 0.7020 | 1.982 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -12.15 | 1.229 | -0.1075 | -0.06320 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4033 | 1.463 | -5.606 | 3.135 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1416 | 0.07801 | -0.9461 | -2.867 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.063 | 1.817 | 1.008 | -2.075 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 42</span>| 474.85832 | 1.003 | -1.150 | -0.9245 | -0.9383 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.005 | -0.9775 | 0.03184 | -0.7513 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7597 | -0.8823 | -0.7996 | -1.089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5032 | -0.8605 | -1.061 | -0.2334 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.85832 | 91.32 | -5.350 | -0.9026 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.618 | 0.4162 | 1.206 | 0.06204 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7875 | 0.7089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.614 | 0.9665 | 0.7015 | 1.983 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.85832</span> | 91.32 | 0.004746 | 0.2885 | 0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009875 | 0.6026 | 1.206 | 0.06204 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7875 | 0.7089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.614 | 0.9665 | 0.7015 | 1.983 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.689 | 1.242 | 0.1265 | -0.09001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3949 | 1.405 | -5.495 | 3.344 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1166 | 0.02645 | -0.9105 | -0.7126 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.952 | 1.861 | 0.8779 | -2.102 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 43</span>| 474.83791 | 1.001 | -1.151 | -0.9246 | -0.9382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.006 | -0.9784 | 0.03545 | -0.7535 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7596 | -0.8823 | -0.7990 | -1.088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5052 | -0.8617 | -1.062 | -0.2320 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.83791 | 91.10 | -5.351 | -0.9027 | -2.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.618 | 0.4158 | 1.208 | 0.06198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7879 | 0.7094 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.612 | 0.9653 | 0.7010 | 1.985 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.83791</span> | 91.10 | 0.004742 | 0.2885 | 0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009872 | 0.6025 | 1.208 | 0.06198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7879 | 0.7094 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.612 | 0.9653 | 0.7010 | 1.985 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -15.77 | 1.225 | -0.1616 | -0.05944 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4032 | 1.455 | -5.461 | 3.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1419 | 0.08593 | -0.9091 | -0.8855 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.951 | 1.791 | 0.9091 | -2.062 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 44</span>| 474.78971 | 1.004 | -1.152 | -0.9246 | -0.9381 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.006 | -0.9794 | 0.03911 | -0.7559 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7597 | -0.8824 | -0.7984 | -1.089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5068 | -0.8614 | -1.062 | -0.2307 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.78971 | 91.33 | -5.352 | -0.9026 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.618 | 0.4153 | 1.209 | 0.06191 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7883 | 0.7086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.610 | 0.9656 | 0.7006 | 1.986 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.78971</span> | 91.33 | 0.004738 | 0.2885 | 0.1107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009869 | 0.6024 | 1.209 | 0.06191 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7883 | 0.7086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.610 | 0.9656 | 0.7006 | 1.986 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.398 | 1.237 | 0.1402 | -0.09195 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3940 | 1.388 | -4.885 | 3.322 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1374 | 0.01792 | -0.6865 | -2.709 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.810 | 1.778 | 0.8100 | -2.095 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 45</span>| 474.76763 | 1.001 | -1.153 | -0.9247 | -0.9380 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.006 | -0.9804 | 0.04256 | -0.7584 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7597 | -0.8824 | -0.7979 | -1.088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5086 | -0.8621 | -1.063 | -0.2293 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.76763 | 91.11 | -5.353 | -0.9027 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.619 | 0.4149 | 1.211 | 0.06184 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7887 | 0.7097 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.608 | 0.9650 | 0.7001 | 1.988 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.76763</span> | 91.11 | 0.004734 | 0.2885 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009867 | 0.6023 | 1.211 | 0.06184 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7887 | 0.7097 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.608 | 0.9650 | 0.7001 | 1.988 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -14.92 | 1.222 | -0.1466 | -0.06186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4014 | 1.433 | -4.989 | 3.157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1326 | 0.08284 | -0.6789 | -2.803 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.814 | 1.775 | 0.8327 | -2.053 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 46</span>| 474.71973 | 1.004 | -1.154 | -0.9246 | -0.9379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.006 | -0.9816 | 0.04617 | -0.7611 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7597 | -0.8824 | -0.7975 | -1.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5100 | -0.8614 | -1.064 | -0.2281 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.71973 | 91.32 | -5.354 | -0.9026 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.619 | 0.4143 | 1.212 | 0.06176 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7890 | 0.7100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.606 | 0.9656 | 0.6996 | 1.990 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.71973</span> | 91.32 | 0.004729 | 0.2885 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009863 | 0.6021 | 1.212 | 0.06176 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7890 | 0.7100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.606 | 0.9656 | 0.6996 | 1.990 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.021 | 1.236 | 0.1299 | -0.09158 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3929 | 1.368 | -4.925 | 3.331 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07142 | 0.08893 | -0.6522 | -2.634 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.639 | 1.780 | 0.7273 | -2.085 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 47</span>| 474.70040 | 1.001 | -1.155 | -0.9247 | -0.9379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.007 | -0.9826 | 0.04954 | -0.7634 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7597 | -0.8825 | -0.7971 | -1.086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5117 | -0.8624 | -1.064 | -0.2267 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.7004 | 91.10 | -5.355 | -0.9027 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.619 | 0.4139 | 1.214 | 0.06169 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7893 | 0.7114 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.604 | 0.9647 | 0.6992 | 1.991 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.7004</span> | 91.10 | 0.004724 | 0.2885 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009861 | 0.6020 | 1.214 | 0.06169 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7893 | 0.7114 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.604 | 0.9647 | 0.6992 | 1.991 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -15.76 | 1.220 | -0.1617 | -0.06091 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4007 | 1.415 | -5.116 | 3.166 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1298 | 0.07714 | -0.6701 | -2.700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.670 | 1.748 | 0.7590 | -2.043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 48</span>| 474.65116 | 1.003 | -1.156 | -0.9246 | -0.9378 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.007 | -0.9837 | 0.05321 | -0.7662 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7598 | -0.8825 | -0.7967 | -1.086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5130 | -0.8617 | -1.065 | -0.2255 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.65116 | 91.32 | -5.356 | -0.9026 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.620 | 0.4134 | 1.215 | 0.06161 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7896 | 0.7116 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.603 | 0.9653 | 0.6987 | 1.993 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.65116</span> | 91.32 | 0.004720 | 0.2885 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009857 | 0.6019 | 1.215 | 0.06161 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7896 | 0.7116 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.603 | 0.9653 | 0.6987 | 1.993 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.462 | 1.239 | 0.1107 | -0.09136 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3915 | 1.348 | -5.441 | 3.268 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1113 | 0.02510 | -0.6252 | -2.485 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.647 | 1.796 | 0.6587 | -2.076 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 49</span>| 474.63065 | 1.001 | -1.157 | -0.9247 | -0.9377 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.007 | -0.9846 | 0.05678 | -0.7683 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7597 | -0.8825 | -0.7963 | -1.084 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5148 | -0.8629 | -1.065 | -0.2241 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.63065 | 91.11 | -5.357 | -0.9027 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.620 | 0.4129 | 1.217 | 0.06155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7899 | 0.7131 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.600 | 0.9642 | 0.6984 | 1.994 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.63065</span> | 91.11 | 0.004716 | 0.2885 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009855 | 0.6018 | 1.217 | 0.06155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7899 | 0.7131 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.600 | 0.9642 | 0.6984 | 1.994 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -14.93 | 1.220 | -0.1531 | -0.06288 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3983 | 1.394 | -5.436 | 3.113 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1458 | 0.07621 | -0.8397 | -0.6848 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.501 | 1.690 | 0.6891 | -2.034 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 50</span>| 474.58497 | 1.004 | -1.158 | -0.9246 | -0.9376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.008 | -0.9857 | 0.06060 | -0.7708 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7598 | -0.8826 | -0.7958 | -1.084 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5162 | -0.8624 | -1.065 | -0.2230 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.58497 | 91.34 | -5.358 | -0.9027 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.620 | 0.4125 | 1.218 | 0.06148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7902 | 0.7126 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.599 | 0.9647 | 0.6980 | 1.996 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.58497</span> | 91.34 | 0.004711 | 0.2885 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009852 | 0.6017 | 1.218 | 0.06148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7902 | 0.7126 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.599 | 0.9647 | 0.6980 | 1.996 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.248 | 1.234 | 0.1371 | -0.09456 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3896 | 1.328 | -5.011 | 3.180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1110 | 0.004022 | -0.8103 | -0.4964 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.349 | 1.713 | 0.5705 | -2.061 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 51</span>| 474.55760 | 1.002 | -1.159 | -0.9247 | -0.9376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.008 | -0.9867 | 0.06444 | -0.7734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7598 | -0.8826 | -0.7952 | -1.085 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5178 | -0.8626 | -1.066 | -0.2215 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.5576 | 91.15 | -5.359 | -0.9027 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.620 | 0.4120 | 1.220 | 0.06140 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7907 | 0.7122 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.597 | 0.9645 | 0.6977 | 1.998 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.5576</span> | 91.15 | 0.004706 | 0.2885 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009849 | 0.6016 | 1.220 | 0.06140 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8777 | 0.05824 | 0.7907 | 0.7122 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.597 | 0.9645 | 0.6977 | 1.998 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -11.86 | 1.219 | -0.1003 | -0.07615 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3954 | 1.369 | -4.929 | 3.171 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1229 | 0.06540 | -0.8183 | -0.7141 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.360 | 1.696 | 0.6359 | -2.032 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 52</span>| 474.51619 | 1.004 | -1.160 | -0.9246 | -0.9375 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.008 | -0.9878 | 0.06816 | -0.7761 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7599 | -0.8826 | -0.7946 | -1.086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5193 | -0.8622 | -1.066 | -0.2202 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.51619 | 91.33 | -5.360 | -0.9027 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.621 | 0.4115 | 1.221 | 0.06132 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8776 | 0.05823 | 0.7911 | 0.7113 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.595 | 0.9648 | 0.6972 | 1.999 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.51619</span> | 91.33 | 0.004702 | 0.2885 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009846 | 0.6014 | 1.221 | 0.06132 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8776 | 0.05823 | 0.7911 | 0.7113 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.595 | 0.9648 | 0.6972 | 1.999 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.413 | 1.225 | 0.1371 | -0.09620 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3880 | 1.314 | -5.554 | 3.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07604 | 0.008867 | -0.7931 | -0.6282 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.148 | 1.715 | 0.5273 | -2.052 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 53</span>| 474.48673 | 1.002 | -1.161 | -0.9247 | -0.9374 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.009 | -0.9889 | 0.07224 | -0.7786 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7599 | -0.8826 | -0.7941 | -1.086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5208 | -0.8625 | -1.067 | -0.2188 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.48673 | 91.17 | -5.361 | -0.9027 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.621 | 0.4110 | 1.223 | 0.06125 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8776 | 0.05823 | 0.7915 | 0.7110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.593 | 0.9645 | 0.6969 | 2.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.48673</span> | 91.17 | 0.004697 | 0.2885 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009843 | 0.6013 | 1.223 | 0.06125 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8776 | 0.05823 | 0.7915 | 0.7110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.593 | 0.9645 | 0.6969 | 2.001 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -10.51 | 1.211 | -0.06554 | -0.07429 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3932 | 1.350 | -4.456 | 3.182 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.08901 | 0.05354 | -0.5957 | -2.739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.160 | 1.696 | 0.5687 | -2.022 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 54</span>| 474.45218 | 1.004 | -1.162 | -0.9246 | -0.9373 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.009 | -0.9900 | 0.07590 | -0.7814 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7601 | -0.8826 | -0.7937 | -1.086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5220 | -0.8620 | -1.067 | -0.2177 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.45218 | 91.40 | -5.362 | -0.9027 | -2.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.621 | 0.4105 | 1.224 | 0.06117 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8776 | 0.05823 | 0.7918 | 0.7111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.592 | 0.9650 | 0.6965 | 2.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.45218</span> | 91.40 | 0.004692 | 0.2885 | 0.1108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009840 | 0.6012 | 1.224 | 0.06117 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8776 | 0.05823 | 0.7918 | 0.7111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.592 | 0.9650 | 0.6965 | 2.002 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 9.724 | 1.224 | 0.2009 | -0.1069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3834 | 1.279 | -5.556 | 3.324 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1101 | -0.01912 | -0.5638 | -2.553 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.043 | 1.731 | 0.4140 | -2.044 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 55</span>| 474.41257 | 1.003 | -1.163 | -0.9246 | -0.9371 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.009 | -0.9913 | 0.07979 | -0.7844 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7601 | -0.8825 | -0.7935 | -1.085 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5231 | -0.8612 | -1.068 | -0.2167 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.41257 | 91.25 | -5.363 | -0.9026 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.622 | 0.4099 | 1.226 | 0.06108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8775 | 0.05824 | 0.7919 | 0.7118 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.591 | 0.9658 | 0.6961 | 2.004 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.41257</span> | 91.25 | 0.004687 | 0.2885 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009836 | 0.6011 | 1.226 | 0.06108 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8775 | 0.05824 | 0.7919 | 0.7118 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.591 | 0.9658 | 0.6961 | 2.004 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.208 | 1.213 | 0.03978 | -0.08693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3876 | 1.303 | -5.023 | 3.218 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1347 | 0.02311 | -0.7771 | -0.6556 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.056 | 1.822 | 0.4520 | -2.025 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 56</span>| 474.39271 | 1.005 | -1.164 | -0.9246 | -0.9371 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.010 | -0.9922 | 0.08348 | -0.7867 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7600 | -0.8825 | -0.7930 | -1.085 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5246 | -0.8625 | -1.068 | -0.2152 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.39271 | 91.47 | -5.364 | -0.9027 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.622 | 0.4094 | 1.228 | 0.06101 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8776 | 0.05824 | 0.7923 | 0.7123 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.589 | 0.9645 | 0.6958 | 2.005 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.39271</span> | 91.47 | 0.004683 | 0.2885 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009833 | 0.6010 | 1.228 | 0.06101 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8776 | 0.05824 | 0.7923 | 0.7123 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.589 | 0.9645 | 0.6958 | 2.005 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 15.86 | 1.227 | 0.2807 | -0.1163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3793 | 1.243 | -5.494 | 3.329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09368 | 0.01293 | -0.5149 | -2.407 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.979 | 1.686 | 0.3308 | -2.044 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 57</span>| 474.34538 | 1.003 | -1.165 | -0.9247 | -0.9369 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.010 | -0.9934 | 0.08718 | -0.7897 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7601 | -0.8825 | -0.7926 | -1.086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5258 | -0.8620 | -1.068 | -0.2141 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.34538 | 91.27 | -5.365 | -0.9027 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.622 | 0.4089 | 1.229 | 0.06093 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8775 | 0.05824 | 0.7926 | 0.7117 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.587 | 0.9650 | 0.6954 | 2.007 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.34538</span> | 91.27 | 0.004677 | 0.2885 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009830 | 0.6008 | 1.229 | 0.06093 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8775 | 0.05824 | 0.7926 | 0.7117 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.587 | 0.9650 | 0.6954 | 2.007 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.345 | 1.210 | 0.04189 | -0.08986 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3855 | 1.284 | -5.145 | 3.218 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1284 | 0.01309 | -0.7466 | -0.6536 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.964 | 1.743 | 0.3816 | -2.008 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 58</span>| 474.31834 | 1.005 | -1.166 | -0.9247 | -0.9369 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.010 | -0.9944 | 0.09109 | -0.7921 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7600 | -0.8825 | -0.7920 | -1.085 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5273 | -0.8633 | -1.069 | -0.2126 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.31834 | 91.43 | -5.366 | -0.9027 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.623 | 0.4085 | 1.231 | 0.06086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8776 | 0.05824 | 0.7930 | 0.7121 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.586 | 0.9638 | 0.6952 | 2.008 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.31834</span> | 91.43 | 0.004673 | 0.2885 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009827 | 0.6007 | 1.231 | 0.06086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8776 | 0.05824 | 0.7930 | 0.7121 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.586 | 0.9638 | 0.6952 | 2.008 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 12.13 | 1.219 | 0.2312 | -0.1125 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3787 | 1.238 | -5.317 | 3.196 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.08361 | -0.02599 | -0.7000 | -0.4940 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.837 | 1.637 | 0.3211 | -2.028 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 59</span>| 474.27833 | 1.003 | -1.167 | -0.9247 | -0.9368 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.010 | -0.9955 | 0.09487 | -0.7949 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7601 | -0.8825 | -0.7915 | -1.086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5286 | -0.8630 | -1.069 | -0.2114 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.27833 | 91.25 | -5.367 | -0.9028 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.623 | 0.4080 | 1.232 | 0.06078 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8775 | 0.05824 | 0.7934 | 0.7111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.584 | 0.9640 | 0.6948 | 2.010 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.27833</span> | 91.25 | 0.004668 | 0.2885 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009824 | 0.6006 | 1.232 | 0.06078 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8775 | 0.05824 | 0.7934 | 0.7111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.584 | 0.9640 | 0.6948 | 2.010 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.145 | 1.202 | 0.02355 | -0.08919 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3842 | 1.275 | -5.102 | 3.189 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1071 | 0.01700 | -0.7283 | -0.7209 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.776 | 1.686 | 0.3249 | -1.982 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 60</span>| 474.25305 | 1.005 | -1.168 | -0.9247 | -0.9367 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.011 | -0.9965 | 0.09878 | -0.7975 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7601 | -0.8825 | -0.7909 | -1.086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5300 | -0.8636 | -1.069 | -0.2100 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.25305 | 91.44 | -5.368 | -0.9028 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.623 | 0.4075 | 1.234 | 0.06070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8775 | 0.05824 | 0.7938 | 0.7109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.583 | 0.9635 | 0.6946 | 2.012 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.25305</span> | 91.44 | 0.004663 | 0.2885 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009821 | 0.6005 | 1.234 | 0.06070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8775 | 0.05824 | 0.7938 | 0.7109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.583 | 0.9635 | 0.6946 | 2.012 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 13.11 | 1.213 | 0.2527 | -0.1161 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3767 | 1.219 | -5.003 | 3.213 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09270 | -0.04298 | -0.4814 | -2.533 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.730 | 1.613 | 0.2495 | -2.014 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 61</span>| 474.21254 | 1.003 | -1.169 | -0.9248 | -0.9365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.011 | -0.9977 | 0.1025 | -0.8005 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7602 | -0.8824 | -0.7906 | -1.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5311 | -0.8630 | -1.070 | -0.2089 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.21254 | 91.24 | -5.369 | -0.9028 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.624 | 0.4069 | 1.236 | 0.06062 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8775 | 0.05824 | 0.7941 | 0.7105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.581 | 0.9641 | 0.6942 | 2.013 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.21254</span> | 91.24 | 0.004658 | 0.2885 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009817 | 0.6003 | 1.236 | 0.06062 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8775 | 0.05824 | 0.7941 | 0.7105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.581 | 0.9641 | 0.6942 | 2.013 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.267 | 1.195 | 0.01760 | -0.08987 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3825 | 1.260 | -5.272 | 3.141 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1336 | 0.009843 | -0.5186 | -2.706 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.727 | 1.652 | 0.2904 | -1.976 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 62</span>| 474.18171 | 1.004 | -1.170 | -0.9247 | -0.9364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.011 | -0.9989 | 0.1065 | -0.8033 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7602 | -0.8823 | -0.7904 | -1.086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5322 | -0.8627 | -1.070 | -0.2078 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.18171 | 91.41 | -5.370 | -0.9028 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.624 | 0.4064 | 1.237 | 0.06054 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8775 | 0.05824 | 0.7942 | 0.7112 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.580 | 0.9644 | 0.6939 | 2.014 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.18171</span> | 91.41 | 0.004653 | 0.2885 | 0.1109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009814 | 0.6002 | 1.237 | 0.06054 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8775 | 0.05824 | 0.7942 | 0.7112 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.580 | 0.9644 | 0.6939 | 2.014 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 9.716 | 1.206 | 0.2113 | -0.1128 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3755 | 1.207 | -5.399 | 3.226 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09670 | -0.03459 | -0.6713 | -0.5638 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.619 | 1.687 | 0.2005 | -1.998 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 63</span>| 474.14509 | 1.003 | -1.171 | -0.9248 | -0.9363 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.012 | -1.000 | 0.1105 | -0.8061 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7602 | -0.8822 | -0.7900 | -1.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5333 | -0.8621 | -1.071 | -0.2068 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.14509 | 91.25 | -5.371 | -0.9028 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.624 | 0.4059 | 1.239 | 0.06045 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8775 | 0.05825 | 0.7945 | 0.7106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.579 | 0.9649 | 0.6936 | 2.015 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.14509</span> | 91.25 | 0.004648 | 0.2885 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009811 | 0.6001 | 1.239 | 0.06045 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8775 | 0.05825 | 0.7945 | 0.7106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.579 | 0.9649 | 0.6936 | 2.015 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.280 | 1.192 | 0.02321 | -0.09129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3799 | 1.239 | -5.339 | 3.156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1074 | 0.06181 | -0.4875 | -2.680 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.648 | 1.743 | 0.2195 | -1.955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 64</span>| 474.11542 | 1.005 | -1.172 | -0.9248 | -0.9361 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.012 | -1.001 | 0.1146 | -0.8089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7603 | -0.8821 | -0.7897 | -1.086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5344 | -0.8621 | -1.071 | -0.2057 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.11542 | 91.42 | -5.372 | -0.9028 | -2.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.625 | 0.4054 | 1.241 | 0.06037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8774 | 0.05825 | 0.7947 | 0.7110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.577 | 0.9649 | 0.6934 | 2.017 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.11542</span> | 91.42 | 0.004643 | 0.2885 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009807 | 0.6000 | 1.241 | 0.06037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8774 | 0.05825 | 0.7947 | 0.7110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.577 | 0.9649 | 0.6934 | 2.017 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 10.52 | 1.202 | 0.2258 | -0.1162 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3725 | 1.186 | -5.381 | 3.222 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1104 | -0.04157 | -0.6550 | -0.5841 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.505 | 1.701 | 0.1753 | -1.993 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 65</span>| 474.07794 | 1.003 | -1.173 | -0.9248 | -0.9360 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.012 | -1.002 | 0.1187 | -0.8117 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7604 | -0.8821 | -0.7895 | -1.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5355 | -0.8615 | -1.071 | -0.2048 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.07794 | 91.25 | -5.373 | -0.9028 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.625 | 0.4048 | 1.242 | 0.06029 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8774 | 0.05825 | 0.7949 | 0.7104 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.576 | 0.9655 | 0.6932 | 2.018 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.07794</span> | 91.25 | 0.004638 | 0.2885 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009804 | 0.5999 | 1.242 | 0.06029 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8774 | 0.05825 | 0.7949 | 0.7104 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.576 | 0.9655 | 0.6932 | 2.018 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.801 | 1.188 | 0.03689 | -0.09236 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3785 | 1.221 | -5.368 | 3.104 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1066 | 0.003449 | -0.6711 | -0.7398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.563 | 1.803 | 0.1884 | -1.939 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 66</span>| 474.04951 | 1.005 | -1.175 | -0.9248 | -0.9359 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.013 | -1.003 | 0.1228 | -0.8144 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7604 | -0.8820 | -0.7890 | -1.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5367 | -0.8618 | -1.071 | -0.2036 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.04951 | 91.43 | -5.375 | -0.9028 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.625 | 0.4044 | 1.244 | 0.06021 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8774 | 0.05825 | 0.7952 | 0.7100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.575 | 0.9652 | 0.6930 | 2.019 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.04951</span> | 91.43 | 0.004633 | 0.2885 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009801 | 0.5997 | 1.244 | 0.06021 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8774 | 0.05825 | 0.7952 | 0.7100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.575 | 0.9652 | 0.6930 | 2.019 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 10.86 | 1.196 | 0.2377 | -0.1190 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3700 | 1.169 | -5.399 | 3.259 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09645 | -0.03914 | -0.4400 | -2.610 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.421 | 1.705 | 0.1351 | -1.978 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 67</span>| 474.01246 | 1.003 | -1.176 | -0.9249 | -0.9357 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.013 | -1.004 | 0.1268 | -0.8173 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7606 | -0.8819 | -0.7888 | -1.088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5377 | -0.8613 | -1.072 | -0.2028 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.01246 | 91.25 | -5.376 | -0.9029 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.626 | 0.4039 | 1.246 | 0.06013 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8773 | 0.05825 | 0.7954 | 0.7098 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.573 | 0.9657 | 0.6927 | 2.020 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.01246</span> | 91.25 | 0.004628 | 0.2885 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009798 | 0.5996 | 1.246 | 0.06013 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8773 | 0.05825 | 0.7954 | 0.7098 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.573 | 0.9657 | 0.6927 | 2.020 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.724 | 1.179 | 0.03043 | -0.09493 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3750 | 1.206 | -5.283 | 3.092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09863 | -0.01543 | -0.6573 | -0.7980 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.377 | 1.778 | 0.1578 | -1.944 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 68</span>| 473.98155 | 1.005 | -1.177 | -0.9249 | -0.9356 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.013 | -1.005 | 0.1310 | -0.8202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7607 | -0.8818 | -0.7885 | -1.088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5387 | -0.8611 | -1.072 | -0.2018 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.98155 | 91.42 | -5.377 | -0.9029 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.626 | 0.4034 | 1.247 | 0.06004 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8773 | 0.05826 | 0.7956 | 0.7095 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.572 | 0.9659 | 0.6925 | 2.022 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.98155</span> | 91.42 | 0.004623 | 0.2885 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009794 | 0.5995 | 1.247 | 0.06004 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8773 | 0.05826 | 0.7956 | 0.7095 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.572 | 0.9659 | 0.6925 | 2.022 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 9.125 | 1.189 | 0.2215 | -0.1183 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3680 | 1.157 | -5.346 | 3.214 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06695 | -0.05805 | -0.6245 | -0.6678 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.365 | 1.770 | 0.07348 | -1.960 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 69</span>| 473.94647 | 1.003 | -1.178 | -0.9250 | -0.9354 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.014 | -1.007 | 0.1350 | -0.8231 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7608 | -0.8817 | -0.7881 | -1.089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5397 | -0.8608 | -1.072 | -0.2009 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.94647 | 91.26 | -5.378 | -0.9030 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.626 | 0.4029 | 1.249 | 0.05996 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8772 | 0.05826 | 0.7959 | 0.7086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.571 | 0.9661 | 0.6923 | 2.023 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.94647</span> | 91.26 | 0.004618 | 0.2884 | 0.1110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009791 | 0.5994 | 1.249 | 0.05996 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8772 | 0.05826 | 0.7959 | 0.7086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.571 | 0.9661 | 0.6923 | 2.023 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.271 | 1.174 | 0.04603 | -0.09766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3725 | 1.188 | -5.320 | 3.084 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09768 | -0.01918 | -0.6378 | -0.8469 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.360 | 1.825 | 0.08453 | -1.920 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 70</span>| 473.91708 | 1.005 | -1.179 | -0.9250 | -0.9353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.014 | -1.008 | 0.1391 | -0.8259 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7609 | -0.8816 | -0.7877 | -1.089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5408 | -0.8610 | -1.072 | -0.1999 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.91708 | 91.43 | -5.379 | -0.9030 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.627 | 0.4024 | 1.251 | 0.05988 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8772 | 0.05826 | 0.7962 | 0.7081 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.570 | 0.9660 | 0.6921 | 2.024 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.91708</span> | 91.43 | 0.004613 | 0.2884 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009788 | 0.5993 | 1.251 | 0.05988 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8772 | 0.05826 | 0.7962 | 0.7081 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.570 | 0.9660 | 0.6921 | 2.024 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 9.919 | 1.183 | 0.2388 | -0.1221 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3649 | 1.138 | -5.295 | 3.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.05759 | -0.06746 | -0.6018 | -0.7458 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.218 | 1.797 | 0.02666 | -1.950 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 71</span>| 473.88166 | 1.003 | -1.180 | -0.9251 | -0.9351 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.014 | -1.009 | 0.1432 | -0.8289 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7611 | -0.8814 | -0.7874 | -1.090 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5418 | -0.8607 | -1.072 | -0.1991 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.88166 | 91.26 | -5.380 | -0.9031 | -2.198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.627 | 0.4019 | 1.252 | 0.05979 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8771 | 0.05827 | 0.7964 | 0.7073 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.568 | 0.9662 | 0.6919 | 2.025 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.88166</span> | 91.26 | 0.004608 | 0.2884 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009785 | 0.5991 | 1.252 | 0.05979 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8771 | 0.05827 | 0.7964 | 0.7073 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.568 | 0.9662 | 0.6919 | 2.025 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.370 | 1.167 | 0.05346 | -0.09978 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3701 | 1.174 | -5.172 | 3.105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07011 | -0.02516 | -0.4239 | -2.943 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.187 | 1.854 | 0.07395 | -1.907 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 72</span>| 473.85215 | 1.005 | -1.181 | -0.9251 | -0.9350 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.015 | -1.010 | 0.1472 | -0.8318 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7612 | -0.8813 | -0.7872 | -1.090 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5427 | -0.8608 | -1.073 | -0.1983 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.85215 | 91.44 | -5.381 | -0.9031 | -2.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.627 | 0.4014 | 1.254 | 0.05971 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8771 | 0.05827 | 0.7965 | 0.7078 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.567 | 0.9662 | 0.6918 | 2.026 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.85215</span> | 91.44 | 0.004603 | 0.2884 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009781 | 0.5990 | 1.254 | 0.05971 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8771 | 0.05827 | 0.7965 | 0.7078 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.567 | 0.9662 | 0.6918 | 2.026 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 10.42 | 1.179 | 0.2474 | -0.1240 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3627 | 1.120 | -5.345 | 3.221 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07960 | -0.04998 | -0.3836 | -2.755 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.094 | 1.797 | -0.01014 | -1.939 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 73</span>| 473.81514 | 1.003 | -1.182 | -0.9251 | -0.9348 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.015 | -1.011 | 0.1513 | -0.8349 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7614 | -0.8810 | -0.7873 | -1.089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5432 | -0.8601 | -1.073 | -0.1979 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.81514 | 91.27 | -5.382 | -0.9031 | -2.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.628 | 0.4008 | 1.256 | 0.05962 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8770 | 0.05828 | 0.7964 | 0.7084 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.567 | 0.9669 | 0.6916 | 2.026 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.81514</span> | 91.27 | 0.004598 | 0.2884 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009778 | 0.5989 | 1.256 | 0.05962 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8770 | 0.05828 | 0.7964 | 0.7084 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.567 | 0.9669 | 0.6916 | 2.026 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.811 | 1.166 | 0.05684 | -0.1019 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3663 | 1.150 | -5.276 | 3.057 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06818 | -0.03474 | -0.4125 | -2.836 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.158 | 1.851 | 0.03258 | -1.914 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 74</span>| 473.78884 | 1.005 | -1.183 | -0.9252 | -0.9346 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.015 | -1.012 | 0.1554 | -0.8377 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7615 | -0.8808 | -0.7873 | -1.088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5439 | -0.8602 | -1.073 | -0.1971 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.78884 | 91.46 | -5.383 | -0.9031 | -2.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.628 | 0.4003 | 1.257 | 0.05954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8770 | 0.05829 | 0.7965 | 0.7095 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.566 | 0.9667 | 0.6915 | 2.027 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.78884</span> | 91.46 | 0.004593 | 0.2884 | 0.1111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009775 | 0.5988 | 1.257 | 0.05954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8770 | 0.05829 | 0.7965 | 0.7095 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.566 | 0.9667 | 0.6915 | 2.027 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 12.26 | 1.178 | 0.2628 | -0.1282 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3579 | 1.094 | -5.180 | 3.234 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.08932 | -0.09780 | -0.5652 | -0.6340 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.031 | 1.841 | -0.06209 | -1.938 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 75</span>| 473.75065 | 1.003 | -1.184 | -0.9252 | -0.9344 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.016 | -1.013 | 0.1594 | -0.8407 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7617 | -0.8806 | -0.7872 | -1.088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5446 | -0.8597 | -1.073 | -0.1966 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.75065 | 91.27 | -5.384 | -0.9032 | -2.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.628 | 0.3998 | 1.259 | 0.05945 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8769 | 0.05829 | 0.7965 | 0.7092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.565 | 0.9672 | 0.6914 | 2.028 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.75065</span> | 91.27 | 0.004588 | 0.2884 | 0.1112 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009772 | 0.5986 | 1.259 | 0.05945 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8769 | 0.05829 | 0.7965 | 0.7092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.565 | 0.9672 | 0.6914 | 2.028 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.250 | 1.164 | 0.05078 | -0.1019 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3635 | 1.132 | -5.308 | 3.057 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09569 | -0.05602 | -0.5891 | -0.8121 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.074 | 1.883 | 0.002586 | -1.906 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 76</span>| 473.72028 | 1.005 | -1.185 | -0.9252 | -0.9343 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.016 | -1.014 | 0.1635 | -0.8437 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7618 | -0.8804 | -0.7870 | -1.089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5455 | -0.8599 | -1.073 | -0.1958 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.72028 | 91.43 | -5.385 | -0.9032 | -2.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.629 | 0.3993 | 1.261 | 0.05936 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8768 | 0.05830 | 0.7967 | 0.7088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.564 | 0.9671 | 0.6912 | 2.029 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.72028</span> | 91.43 | 0.004583 | 0.2884 | 0.1112 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009768 | 0.5985 | 1.261 | 0.05936 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8768 | 0.05830 | 0.7967 | 0.7088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.564 | 0.9671 | 0.6912 | 2.029 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 8.975 | 1.171 | 0.2290 | -0.1246 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3563 | 1.085 | -5.320 | 3.173 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.08707 | -0.1016 | -0.5561 | -0.7117 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9536 | 1.850 | -0.07963 | -1.922 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 77</span>| 473.68600 | 1.003 | -1.186 | -0.9253 | -0.9341 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.016 | -1.015 | 0.1676 | -0.8467 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7620 | -0.8801 | -0.7868 | -1.089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5463 | -0.8596 | -1.073 | -0.1952 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.686 | 91.28 | -5.386 | -0.9033 | -2.196 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.629 | 0.3989 | 1.263 | 0.05928 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8768 | 0.05831 | 0.7968 | 0.7081 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.563 | 0.9673 | 0.6911 | 2.030 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.686</span> | 91.28 | 0.004578 | 0.2884 | 0.1112 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009765 | 0.5984 | 1.263 | 0.05928 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8768 | 0.05831 | 0.7968 | 0.7081 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.563 | 0.9673 | 0.6911 | 2.030 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.608 | 1.155 | 0.05506 | -0.1036 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3607 | 1.118 | -5.212 | 3.031 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.08611 | -0.04336 | -0.3798 | -2.808 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.093 | 1.880 | -0.02731 | -1.896 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 78</span>| 473.65599 | 1.005 | -1.188 | -0.9253 | -0.9339 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.017 | -1.016 | 0.1718 | -0.8497 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7621 | -0.8799 | -0.7868 | -1.089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5471 | -0.8595 | -1.074 | -0.1946 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.65599 | 91.44 | -5.388 | -0.9033 | -2.196 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.629 | 0.3984 | 1.264 | 0.05919 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8767 | 0.05831 | 0.7968 | 0.7087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.562 | 0.9674 | 0.6910 | 2.030 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.65599</span> | 91.44 | 0.004573 | 0.2884 | 0.1112 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009762 | 0.5983 | 1.264 | 0.05919 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8767 | 0.05831 | 0.7968 | 0.7087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.562 | 0.9674 | 0.6910 | 2.030 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 9.720 | 1.170 | 0.2444 | -0.1229 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3557 | 1.067 | -5.275 | 3.173 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07850 | -0.1042 | -0.5348 | -0.6844 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9479 | 1.915 | -0.1018 | -1.917 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 79</span>| 473.62083 | 1.003 | -1.189 | -0.9254 | -0.9337 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.017 | -1.017 | 0.1759 | -0.8528 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7623 | -0.8795 | -0.7869 | -1.089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5477 | -0.8591 | -1.074 | -0.1942 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.62083 | 91.28 | -5.389 | -0.9033 | -2.196 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.630 | 0.3979 | 1.266 | 0.05910 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8766 | 0.05832 | 0.7968 | 0.7085 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.562 | 0.9678 | 0.6909 | 2.031 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.62083</span> | 91.28 | 0.004568 | 0.2884 | 0.1112 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009758 | 0.5982 | 1.266 | 0.05910 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8766 | 0.05832 | 0.7968 | 0.7085 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.562 | 0.9678 | 0.6909 | 2.031 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.323 | 1.153 | 0.05982 | -0.1053 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3572 | 1.098 | -4.702 | 3.058 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1117 | -0.04281 | -0.5573 | -0.7999 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.039 | 1.912 | -0.05974 | -1.890 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 80</span>| 473.59326 | 1.005 | -1.190 | -0.9254 | -0.9335 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.018 | -1.019 | 0.1798 | -0.8560 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7624 | -0.8793 | -0.7867 | -1.090 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5486 | -0.8595 | -1.074 | -0.1934 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.59326 | 91.46 | -5.390 | -0.9034 | -2.196 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.630 | 0.3974 | 1.268 | 0.05901 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8766 | 0.05833 | 0.7969 | 0.7081 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.560 | 0.9674 | 0.6908 | 2.032 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.59326</span> | 91.46 | 0.004562 | 0.2884 | 0.1113 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009755 | 0.5981 | 1.268 | 0.05901 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8766 | 0.05833 | 0.7969 | 0.7081 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.560 | 0.9674 | 0.6908 | 2.032 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 11.25 | 1.162 | 0.2586 | -0.1299 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3499 | 1.048 | -5.229 | 3.126 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.05642 | -0.09930 | -0.3252 | -2.718 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8202 | 1.876 | -0.1477 | -1.910 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 81</span>| 473.55541 | 1.003 | -1.191 | -0.9255 | -0.9333 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.018 | -1.020 | 0.1836 | -0.8595 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7626 | -0.8789 | -0.7868 | -1.090 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5492 | -0.8592 | -1.074 | -0.1932 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.55541 | 91.31 | -5.391 | -0.9034 | -2.196 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.630 | 0.3968 | 1.269 | 0.05891 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8765 | 0.05834 | 0.7968 | 0.7080 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.560 | 0.9677 | 0.6906 | 2.032 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.55541</span> | 91.31 | 0.004557 | 0.2883 | 0.1113 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009751 | 0.5979 | 1.269 | 0.05891 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8765 | 0.05834 | 0.7968 | 0.7080 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.560 | 0.9677 | 0.6906 | 2.032 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.062 | 1.149 | 0.09224 | -0.1103 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3525 | 1.070 | -5.098 | 2.994 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1095 | -0.04877 | -0.3504 | -2.828 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8255 | 1.898 | -0.1147 | -1.889 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 82</span>| 473.53708 | 1.006 | -1.192 | -0.9256 | -0.9332 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.018 | -1.021 | 0.1873 | -0.8616 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7625 | -0.8789 | -0.7866 | -1.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5498 | -0.8606 | -1.074 | -0.1918 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.53708 | 91.52 | -5.392 | -0.9035 | -2.196 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.631 | 0.3964 | 1.271 | 0.05884 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8765 | 0.05834 | 0.7970 | 0.7099 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.559 | 0.9664 | 0.6907 | 2.034 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.53708</span> | 91.52 | 0.004553 | 0.2883 | 0.1113 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009749 | 0.5978 | 1.271 | 0.05884 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8765 | 0.05834 | 0.7970 | 0.7099 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.559 | 0.9664 | 0.6907 | 2.034 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 16.25 | 1.165 | 0.3077 | -0.1378 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3448 | 1.019 | -5.264 | 3.150 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09278 | -0.1366 | -0.2969 | -2.557 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7485 | 1.781 | -0.1828 | -1.909 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 83</span>| 473.49312 | 1.003 | -1.193 | -0.9256 | -0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.018 | -1.022 | 0.1912 | -0.8647 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7626 | -0.8785 | -0.7869 | -1.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5501 | -0.8598 | -1.074 | -0.1918 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.49312 | 91.32 | -5.393 | -0.9035 | -2.195 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.631 | 0.3959 | 1.272 | 0.05875 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8765 | 0.05835 | 0.7967 | 0.7106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.559 | 0.9671 | 0.6906 | 2.034 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.49312</span> | 91.32 | 0.004547 | 0.2883 | 0.1113 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009745 | 0.5977 | 1.272 | 0.05875 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8765 | 0.05835 | 0.7967 | 0.7106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.559 | 0.9671 | 0.6906 | 2.034 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.793 | 1.150 | 0.08391 | -0.1095 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3500 | 1.057 | -5.154 | 2.847 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07414 | -0.06025 | -0.5244 | -0.6779 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8291 | 1.867 | -0.1201 | -1.880 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 84</span>| 473.47390 | 1.006 | -1.194 | -0.9256 | -0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.019 | -1.022 | 0.1953 | -0.8670 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7626 | -0.8785 | -0.7865 | -1.086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5507 | -0.8613 | -1.074 | -0.1903 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.4739 | 91.52 | -5.394 | -0.9036 | -2.195 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.631 | 0.3955 | 1.274 | 0.05869 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8765 | 0.05835 | 0.7970 | 0.7110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.558 | 0.9657 | 0.6907 | 2.036 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.4739</span> | 91.52 | 0.004543 | 0.2883 | 0.1113 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009743 | 0.5976 | 1.274 | 0.05869 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8765 | 0.05835 | 0.7970 | 0.7110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.558 | 0.9657 | 0.6907 | 2.036 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 15.82 | 1.163 | 0.3026 | -0.1376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3423 | 1.007 | -4.821 | 3.176 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06207 | -0.1161 | -0.4712 | -0.4774 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7015 | 1.725 | -0.1877 | -1.896 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 85</span>| 473.43080 | 1.003 | -1.195 | -0.9257 | -0.9326 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.019 | -1.024 | 0.1991 | -0.8700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7628 | -0.8781 | -0.7866 | -1.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5513 | -0.8608 | -1.074 | -0.1899 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.4308 | 91.31 | -5.395 | -0.9036 | -2.195 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.632 | 0.3950 | 1.276 | 0.05860 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8764 | 0.05836 | 0.7970 | 0.7105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.557 | 0.9662 | 0.6906 | 2.036 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.4308</span> | 91.31 | 0.004538 | 0.2883 | 0.1114 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009739 | 0.5975 | 1.276 | 0.05860 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8764 | 0.05836 | 0.7970 | 0.7105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.557 | 0.9662 | 0.6906 | 2.036 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.611 | 1.145 | 0.07564 | -0.1091 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3478 | 1.048 | -5.196 | 2.853 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07176 | -0.06153 | -0.5100 | -0.6862 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7701 | 1.783 | -0.1204 | -1.866 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 86</span>| 473.40390 | 1.005 | -1.196 | -0.9258 | -0.9324 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.019 | -1.025 | 0.2034 | -0.8728 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7629 | -0.8779 | -0.7864 | -1.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5520 | -0.8612 | -1.074 | -0.1890 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.4039 | 91.48 | -5.396 | -0.9037 | -2.195 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.632 | 0.3946 | 1.277 | 0.05852 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8764 | 0.05837 | 0.7971 | 0.7105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.556 | 0.9658 | 0.6906 | 2.037 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.4039</span> | 91.48 | 0.004533 | 0.2883 | 0.1114 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009736 | 0.5974 | 1.277 | 0.05852 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8764 | 0.05837 | 0.7971 | 0.7105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.556 | 0.9658 | 0.6906 | 2.037 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 11.82 | 1.154 | 0.2542 | -0.1321 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3410 | 1.002 | -5.150 | 3.097 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.04820 | -0.1059 | -0.4698 | -0.5387 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6891 | 1.733 | -0.1906 | -1.879 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 87</span>| 473.36686 | 1.003 | -1.198 | -0.9258 | -0.9322 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.020 | -1.026 | 0.2076 | -0.8758 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7631 | -0.8776 | -0.7865 | -1.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5525 | -0.8606 | -1.074 | -0.1886 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.36686 | 91.32 | -5.398 | -0.9037 | -2.195 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.632 | 0.3941 | 1.279 | 0.05843 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8763 | 0.05838 | 0.7970 | 0.7100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.556 | 0.9664 | 0.6905 | 2.038 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.36686</span> | 91.32 | 0.004527 | 0.2883 | 0.1114 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009733 | 0.5973 | 1.279 | 0.05843 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8763 | 0.05838 | 0.7970 | 0.7100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.556 | 0.9664 | 0.6905 | 2.038 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.686 | 1.139 | 0.08028 | -0.1103 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3450 | 1.034 | -5.059 | 2.983 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07022 | -0.06541 | -0.4954 | -0.7148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6839 | 1.782 | -0.1353 | -1.853 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 88</span>| 473.34117 | 1.005 | -1.199 | -0.9259 | -0.9321 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.020 | -1.027 | 0.2118 | -0.8787 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7632 | -0.8774 | -0.7864 | -1.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5531 | -0.8611 | -1.074 | -0.1877 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.34117 | 91.49 | -5.399 | -0.9038 | -2.194 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.633 | 0.3936 | 1.281 | 0.05835 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8763 | 0.05838 | 0.7971 | 0.7100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.555 | 0.9659 | 0.6904 | 2.039 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.34117</span> | 91.49 | 0.004522 | 0.2883 | 0.1114 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009730 | 0.5972 | 1.281 | 0.05835 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8763 | 0.05838 | 0.7971 | 0.7100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.555 | 0.9659 | 0.6904 | 2.039 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 12.62 | 1.149 | 0.2679 | -0.1346 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3379 | 0.9875 | -5.147 | 2.965 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07400 | -0.1145 | -0.4542 | -0.5455 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6283 | 1.734 | -0.2097 | -1.869 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 89</span>| 473.30326 | 1.004 | -1.200 | -0.9259 | -0.9318 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.020 | -1.028 | 0.2159 | -0.8818 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7634 | -0.8771 | -0.7865 | -1.088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5535 | -0.8604 | -1.074 | -0.1874 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.30326 | 91.32 | -5.400 | -0.9038 | -2.194 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.633 | 0.3932 | 1.283 | 0.05826 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8762 | 0.05839 | 0.7970 | 0.7096 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.555 | 0.9665 | 0.6903 | 2.039 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.30326</span> | 91.32 | 0.004517 | 0.2883 | 0.1114 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009726 | 0.5970 | 1.283 | 0.05826 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8762 | 0.05839 | 0.7970 | 0.7096 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.555 | 0.9665 | 0.6903 | 2.039 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.609 | 1.134 | 0.08636 | -0.1114 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3423 | 1.018 | -5.228 | 2.880 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1079 | -0.06580 | -0.2896 | -2.686 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6917 | 1.801 | -0.1599 | -1.842 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 90</span>| 473.27616 | 1.005 | -1.201 | -0.9260 | -0.9316 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.021 | -1.029 | 0.2202 | -0.8845 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7634 | -0.8768 | -0.7866 | -1.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5540 | -0.8607 | -1.074 | -0.1867 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.27616 | 91.48 | -5.401 | -0.9039 | -2.194 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.633 | 0.3927 | 1.284 | 0.05818 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8762 | 0.05840 | 0.7970 | 0.7107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.554 | 0.9663 | 0.6904 | 2.040 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.27616</span> | 91.48 | 0.004512 | 0.2883 | 0.1115 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009723 | 0.5969 | 1.284 | 0.05818 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8762 | 0.05840 | 0.7970 | 0.7107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.554 | 0.9663 | 0.6904 | 2.040 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 11.44 | 1.145 | 0.2516 | -0.1333 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3351 | 0.9744 | -4.753 | 3.090 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.05028 | -0.1148 | -0.4450 | -0.5198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.5573 | 1.743 | -0.2240 | -1.858 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 91</span>| 473.24283 | 1.003 | -1.202 | -0.9260 | -0.9314 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.021 | -1.030 | 0.2240 | -0.8877 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7636 | -0.8764 | -0.7870 | -1.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5543 | -0.8601 | -1.074 | -0.1866 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.24283 | 91.29 | -5.402 | -0.9039 | -2.194 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.634 | 0.3922 | 1.286 | 0.05809 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8761 | 0.05841 | 0.7967 | 0.7107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.554 | 0.9668 | 0.6903 | 2.040 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.24283</span> | 91.29 | 0.004506 | 0.2882 | 0.1115 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009720 | 0.5968 | 1.286 | 0.05809 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8761 | 0.05841 | 0.7967 | 0.7107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.554 | 0.9668 | 0.6903 | 2.040 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -7.383 | 1.129 | 0.03939 | -0.1057 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3410 | 1.013 | -4.733 | 2.907 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07460 | -0.06623 | -0.4732 | -0.6761 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6495 | 1.823 | -0.1637 | -1.832 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 92</span>| 473.20973 | 1.005 | -1.204 | -0.9260 | -0.9311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.021 | -1.031 | 0.2279 | -0.8912 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7638 | -0.8760 | -0.7872 | -1.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5548 | -0.8600 | -1.075 | -0.1862 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.20973 | 91.43 | -5.404 | -0.9039 | -2.193 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.634 | 0.3917 | 1.288 | 0.05799 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8760 | 0.05843 | 0.7966 | 0.7102 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.553 | 0.9669 | 0.6900 | 2.040 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.20973</span> | 91.43 | 0.004500 | 0.2882 | 0.1115 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009716 | 0.5967 | 1.288 | 0.05799 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8760 | 0.05843 | 0.7966 | 0.7102 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.553 | 0.9669 | 0.6900 | 2.040 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 93</span>| 473.17178 | 1.005 | -1.205 | -0.9261 | -0.9307 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.022 | -1.032 | 0.2326 | -0.8959 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7641 | -0.8754 | -0.7876 | -1.088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5554 | -0.8593 | -1.075 | -0.1863 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.17178 | 91.43 | -5.405 | -0.9040 | -2.193 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.634 | 0.3910 | 1.289 | 0.05785 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8759 | 0.05844 | 0.7963 | 0.7092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.552 | 0.9676 | 0.6896 | 2.040 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.17178</span> | 91.43 | 0.004492 | 0.2882 | 0.1116 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009711 | 0.5965 | 1.289 | 0.05785 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8759 | 0.05844 | 0.7963 | 0.7092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.552 | 0.9676 | 0.6896 | 2.040 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 94</span>| 472.97479 | 1.005 | -1.215 | -0.9262 | -0.9287 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.025 | -1.041 | 0.2575 | -0.9212 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7657 | -0.8720 | -0.7899 | -1.094 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5585 | -0.8552 | -1.078 | -0.1866 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 472.97479 | 91.45 | -5.415 | -0.9041 | -2.191 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.637 | 0.3872 | 1.300 | 0.05712 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8752 | 0.05854 | 0.7946 | 0.7037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.549 | 0.9715 | 0.6874 | 2.040 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 472.97479</span> | 91.45 | 0.004449 | 0.2882 | 0.1118 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009685 | 0.5956 | 1.300 | 0.05712 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8752 | 0.05854 | 0.7946 | 0.7037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.549 | 0.9715 | 0.6874 | 2.040 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 95</span>| 472.26932 | 1.006 | -1.253 | -0.9268 | -0.9205 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.035 | -1.074 | 0.3572 | -1.022 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7723 | -0.8583 | -0.7991 | -1.118 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5709 | -0.8392 | -1.088 | -0.1877 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 472.26932 | 91.55 | -5.453 | -0.9046 | -2.183 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.648 | 0.3719 | 1.341 | 0.05419 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8725 | 0.05894 | 0.7878 | 0.6819 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.534 | 0.9868 | 0.6787 | 2.039 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 472.26932</span> | 91.55 | 0.004282 | 0.2881 | 0.1127 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009582 | 0.5919 | 1.341 | 0.05419 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8725 | 0.05894 | 0.7878 | 0.6819 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.534 | 0.9868 | 0.6787 | 2.039 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 96</span>| 470.90347 | 1.012 | -1.408 | -0.9286 | -0.8872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.078 | -1.207 | 0.7550 | -1.427 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7985 | -0.8024 | -0.8343 | -1.204 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6170 | -0.7722 | -1.128 | -0.1957 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 470.90347 | 92.06 | -5.608 | -0.9062 | -2.150 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.691 | 0.3105 | 1.506 | 0.04245 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8616 | 0.06056 | 0.7621 | 0.6043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.480 | 1.051 | 0.6438 | 2.029 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 470.90347</span> | 92.06 | 0.003670 | 0.2878 | 0.1165 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009180 | 0.5770 | 1.506 | 0.04245 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8616 | 0.06056 | 0.7621 | 0.6043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.480 | 1.051 | 0.6438 | 2.029 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 16.46 | 0.7178 | 1.137 | -0.2842 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06515 | -1.058 | -6.810 | -2.325 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1903 | -0.6630 | 1.424 | -9.046 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.659 | 8.235 | -7.307 | -1.506 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 97</span>| 469.55066 | 1.016 | -1.623 | -0.9529 | -0.8214 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.136 | -1.353 | 1.295 | -1.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8595 | -0.6716 | -0.9513 | -1.204 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7087 | -0.8316 | -0.9499 | -0.4083 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 469.55066 | 92.47 | -5.823 | -0.9279 | -2.084 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.749 | 0.2437 | 1.731 | 0.02949 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8363 | 0.06435 | 0.6766 | 0.6043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.371 | 0.9940 | 0.7978 | 1.771 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 469.55066</span> | 92.47 | 0.002960 | 0.2834 | 0.1245 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008661 | 0.5606 | 1.731 | 0.02949 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8363 | 0.06435 | 0.6766 | 0.6043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.371 | 0.9940 | 0.7978 | 1.771 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.003 | 0.4823 | 0.6025 | -0.2481 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.135 | 0.1015 | -5.875 | -8.309 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8363 | -0.7839 | 1.711 | -6.097 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.755 | 1.794 | 4.040 | -0.5408 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 98</span>| 471.32255 | 1.022 | -1.880 | -1.043 | -0.7426 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.107 | -1.512 | 1.956 | -1.964 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9773 | -0.5429 | -1.097 | -1.122 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6469 | -0.5662 | -0.9027 | -0.4752 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 471.32255 | 93.00 | -6.080 | -1.008 | -2.005 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.719 | 0.1705 | 2.005 | 0.02687 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7874 | 0.06809 | 0.5704 | 0.6787 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.444 | 1.248 | 0.8385 | 1.690 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 471.32255</span> | 93.00 | 0.002289 | 0.2674 | 0.1347 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008922 | 0.5425 | 2.005 | 0.02687 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7874 | 0.06809 | 0.5704 | 0.6787 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.444 | 1.248 | 0.8385 | 1.690 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 99</span>| 468.82475 | 1.022 | -1.709 | -0.9836 | -0.7948 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.126 | -1.406 | 1.521 | -1.898 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8984 | -0.6279 | -1.001 | -1.172 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6845 | -0.7440 | -0.9371 | -0.4303 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.82475 | 92.98 | -5.909 | -0.9551 | -2.057 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.738 | 0.2191 | 1.824 | 0.02879 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8201 | 0.06562 | 0.6400 | 0.6333 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.400 | 1.078 | 0.8088 | 1.744 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.82475</span> | 92.98 | 0.002714 | 0.2779 | 0.1278 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008755 | 0.5546 | 1.824 | 0.02879 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8201 | 0.06562 | 0.6400 | 0.6333 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.400 | 1.078 | 0.8088 | 1.744 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 40.86 | 0.3767 | -0.09575 | -0.1893 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.313 | -0.2132 | -3.864 | -4.927 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.292 | -1.079 | -0.1017 | -3.329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.248 | 8.116 | 3.916 | -0.3530 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 100</span>| 467.75171 | 1.017 | -1.816 | -0.9824 | -0.7623 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.067 | -1.470 | 1.678 | -1.962 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9501 | -0.5667 | -0.9995 | -1.140 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5909 | -0.8204 | -1.012 | -0.4878 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.75171 | 92.51 | -6.016 | -0.9541 | -2.025 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.679 | 0.1896 | 1.889 | 0.02693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7987 | 0.06740 | 0.6413 | 0.6622 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.510 | 1.005 | 0.7438 | 1.674 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.75171</span> | 92.51 | 0.002440 | 0.2781 | 0.1320 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.009285 | 0.5473 | 1.889 | 0.02693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7987 | 0.06740 | 0.6413 | 0.6622 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.510 | 1.005 | 0.7438 | 1.674 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -11.72 | 0.1617 | -0.2966 | 0.1391 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7722 | -0.6625 | -3.136 | -6.222 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.617 | -0.9189 | -0.2811 | -3.105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.05355 | 2.320 | -3.473 | -2.160 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 101</span>| 467.28745 | 1.018 | -1.902 | -0.9107 | -0.7577 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9795 | -1.517 | 1.777 | -1.860 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8874 | -0.4787 | -0.8826 | -1.170 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6199 | -0.8544 | -0.9952 | -0.3962 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.28745 | 92.66 | -6.102 | -0.8902 | -2.020 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.592 | 0.1682 | 1.931 | 0.02990 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8247 | 0.06995 | 0.7268 | 0.6357 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.476 | 0.9723 | 0.7587 | 1.785 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.28745</span> | 92.66 | 0.002239 | 0.2911 | 0.1327 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01013 | 0.5420 | 1.931 | 0.02990 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8247 | 0.06995 | 0.7268 | 0.6357 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.476 | 0.9723 | 0.7587 | 1.785 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 21.75 | 0.1003 | 2.571 | 0.1450 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5415 | -1.471 | -1.062 | -1.774 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.363 | 0.7539 | 2.182 | -3.357 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.337 | 0.2346 | -1.234 | -0.8531 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 102</span>| 469.68385 | 0.9954 | -1.950 | -1.032 | -0.7900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8810 | -1.433 | 1.783 | -1.785 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9418 | -0.5114 | -0.9107 | -1.204 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6798 | -0.8966 | -1.014 | -0.2565 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 469.68385 | 90.58 | -6.150 | -0.9984 | -2.052 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.493 | 0.2066 | 1.933 | 0.03207 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8021 | 0.06900 | 0.7062 | 0.6043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.405 | 0.9320 | 0.7422 | 1.955 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 469.68385</span> | 90.58 | 0.002133 | 0.2693 | 0.1284 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01118 | 0.5515 | 1.933 | 0.03207 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8021 | 0.06900 | 0.7062 | 0.6043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.405 | 0.9320 | 0.7422 | 1.955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 103</span>| 467.87907 | 1.005 | -1.909 | -0.9308 | -0.7628 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9639 | -1.503 | 1.779 | -1.847 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8965 | -0.4841 | -0.8880 | -1.173 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6287 | -0.8610 | -0.9975 | -0.3740 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.87907 | 91.48 | -6.109 | -0.9081 | -2.025 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.576 | 0.1745 | 1.931 | 0.03026 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8209 | 0.06979 | 0.7229 | 0.6325 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.466 | 0.9660 | 0.7566 | 1.812 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.87907</span> | 91.48 | 0.002222 | 0.2874 | 0.1320 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01029 | 0.5435 | 1.931 | 0.03026 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8209 | 0.06979 | 0.7229 | 0.6325 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.466 | 0.9660 | 0.7566 | 1.812 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 104</span>| 467.53566 | 1.009 | -1.902 | -0.9117 | -0.7577 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9793 | -1.516 | 1.778 | -1.859 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8880 | -0.4790 | -0.8835 | -1.168 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6194 | -0.8545 | -0.9947 | -0.3959 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.53566 | 91.86 | -6.102 | -0.8912 | -2.020 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.592 | 0.1685 | 1.931 | 0.02992 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8245 | 0.06994 | 0.7261 | 0.6369 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 0.9722 | 0.7591 | 1.786 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.53566</span> | 91.86 | 0.002239 | 0.2909 | 0.1326 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01013 | 0.5420 | 1.931 | 0.02992 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8245 | 0.06994 | 0.7261 | 0.6369 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 0.9722 | 0.7591 | 1.786 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 105</span>| 467.26444 | 1.016 | -1.902 | -0.9109 | -0.7577 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9795 | -1.516 | 1.777 | -1.860 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8875 | -0.4788 | -0.8828 | -1.169 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6198 | -0.8544 | -0.9951 | -0.3961 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.26444 | 92.48 | -6.102 | -0.8905 | -2.020 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.592 | 0.1683 | 1.931 | 0.02990 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8246 | 0.06995 | 0.7266 | 0.6360 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.476 | 0.9723 | 0.7588 | 1.786 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.26444</span> | 92.48 | 0.002239 | 0.2910 | 0.1326 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01013 | 0.5420 | 1.931 | 0.02990 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8246 | 0.06995 | 0.7266 | 0.6360 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.476 | 0.9723 | 0.7588 | 1.786 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.458 | 0.09189 | 2.450 | 0.1713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5320 | -1.492 | -1.346 | -2.030 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.374 | 0.8089 | 1.804 | -5.854 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.303 | 0.2787 | -1.170 | -0.8602 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 106</span>| 467.25360 | 1.017 | -1.902 | -0.9116 | -0.7577 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9793 | -1.516 | 1.778 | -1.859 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8879 | -0.4790 | -0.8833 | -1.168 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6195 | -0.8545 | -0.9948 | -0.3959 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.2536 | 92.51 | -6.102 | -0.8910 | -2.020 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.592 | 0.1685 | 1.931 | 0.02992 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8245 | 0.06994 | 0.7263 | 0.6374 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 0.9722 | 0.7590 | 1.786 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.2536</span> | 92.51 | 0.002239 | 0.2909 | 0.1326 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01013 | 0.5420 | 1.931 | 0.02992 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8245 | 0.06994 | 0.7263 | 0.6374 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 0.9722 | 0.7590 | 1.786 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.196 | 0.08873 | 2.446 | 0.1672 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5342 | -1.484 | -1.056 | -1.956 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.373 | 0.7965 | 2.077 | -5.722 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.292 | 0.2471 | -1.040 | -0.8496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 107</span>| 467.24389 | 1.015 | -1.902 | -0.9128 | -0.7578 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9790 | -1.515 | 1.778 | -1.858 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8886 | -0.4794 | -0.8844 | -1.165 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6188 | -0.8546 | -0.9942 | -0.3955 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.24389 | 92.37 | -6.102 | -0.8922 | -2.020 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.592 | 0.1688 | 1.931 | 0.02995 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8242 | 0.06993 | 0.7255 | 0.6400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 0.9721 | 0.7595 | 1.786 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.24389</span> | 92.37 | 0.002239 | 0.2907 | 0.1326 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01014 | 0.5421 | 1.931 | 0.02995 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8242 | 0.06993 | 0.7255 | 0.6400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 0.9721 | 0.7595 | 1.786 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -15.43 | 0.07336 | 2.305 | 0.1893 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5256 | -1.495 | -1.329 | -2.142 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.357 | 0.9382 | 1.940 | -3.165 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.157 | 0.2760 | -0.9277 | -0.8566 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 108</span>| 467.22397 | 1.017 | -1.902 | -0.9138 | -0.7581 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9782 | -1.514 | 1.778 | -1.857 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8889 | -0.4797 | -0.8863 | -1.164 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6190 | -0.8552 | -0.9945 | -0.3935 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.22397 | 92.56 | -6.102 | -0.8930 | -2.020 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.591 | 0.1692 | 1.931 | 0.02998 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8241 | 0.06992 | 0.7241 | 0.6409 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 0.9715 | 0.7593 | 1.789 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.22397</span> | 92.56 | 0.002238 | 0.2905 | 0.1326 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01015 | 0.5422 | 1.931 | 0.02998 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8241 | 0.06992 | 0.7241 | 0.6409 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 0.9715 | 0.7593 | 1.789 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 8.612 | 0.07601 | 2.377 | 0.1597 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5308 | -1.476 | -1.038 | -1.834 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.332 | 0.7679 | 2.039 | -3.039 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.288 | 0.2037 | -1.093 | -0.8313 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 109</span>| 467.20858 | 1.016 | -1.903 | -0.9153 | -0.7584 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9772 | -1.513 | 1.777 | -1.856 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8896 | -0.4802 | -0.8882 | -1.164 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6194 | -0.8560 | -0.9946 | -0.3915 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.20858 | 92.46 | -6.103 | -0.8944 | -2.021 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.590 | 0.1698 | 1.931 | 0.03001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8238 | 0.06990 | 0.7227 | 0.6411 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 0.9707 | 0.7591 | 1.791 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.20858</span> | 92.46 | 0.002236 | 0.2902 | 0.1325 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01016 | 0.5423 | 1.931 | 0.03001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8238 | 0.06990 | 0.7227 | 0.6411 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 0.9707 | 0.7591 | 1.791 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.651 | 0.07137 | 2.259 | 0.1744 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5171 | -1.486 | -1.304 | -1.934 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.324 | 0.7910 | 1.690 | -3.053 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.233 | 0.1999 | -1.046 | -0.8164 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 110</span>| 467.19548 | 1.017 | -1.903 | -0.9170 | -0.7588 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9762 | -1.512 | 1.778 | -1.855 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8906 | -0.4808 | -0.8898 | -1.163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6195 | -0.8567 | -0.9946 | -0.3897 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.19548 | 92.56 | -6.103 | -0.8959 | -2.021 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.589 | 0.1705 | 1.931 | 0.03005 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8234 | 0.06989 | 0.7215 | 0.6417 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 0.9701 | 0.7592 | 1.793 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.19548</span> | 92.56 | 0.002235 | 0.2899 | 0.1325 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01017 | 0.5425 | 1.931 | 0.03005 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8234 | 0.06989 | 0.7215 | 0.6417 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 0.9701 | 0.7592 | 1.793 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 9.695 | 0.07360 | 2.256 | 0.1610 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5147 | -1.467 | -1.275 | -1.734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.307 | 0.8740 | 2.039 | -5.568 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.898 | -0.2550 | -1.273 | -0.7762 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 111</span>| 467.17845 | 1.016 | -1.904 | -0.9175 | -0.7593 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9751 | -1.510 | 1.777 | -1.854 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8907 | -0.4813 | -0.8918 | -1.161 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6194 | -0.8571 | -0.9949 | -0.3876 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.17845 | 92.50 | -6.104 | -0.8963 | -2.022 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.588 | 0.1711 | 1.930 | 0.03007 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8234 | 0.06987 | 0.7201 | 0.6433 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 0.9697 | 0.7589 | 1.796 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.17845</span> | 92.50 | 0.002234 | 0.2898 | 0.1324 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01018 | 0.5427 | 1.930 | 0.03007 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8234 | 0.06987 | 0.7201 | 0.6433 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 0.9697 | 0.7589 | 1.796 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.021 | 0.06308 | 2.194 | 0.1658 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5050 | -1.471 | -1.283 | -1.811 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.304 | 0.7659 | 1.629 | -2.860 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.234 | 0.1434 | -1.025 | -0.7796 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 112</span>| 467.16518 | 1.015 | -1.904 | -0.9192 | -0.7596 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9742 | -1.509 | 1.777 | -1.853 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8917 | -0.4819 | -0.8931 | -1.160 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6190 | -0.8574 | -0.9946 | -0.3864 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.16518 | 92.39 | -6.104 | -0.8978 | -2.022 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.587 | 0.1719 | 1.931 | 0.03011 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8229 | 0.06985 | 0.7191 | 0.6447 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 0.9694 | 0.7592 | 1.797 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.16518</span> | 92.39 | 0.002234 | 0.2895 | 0.1324 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01019 | 0.5429 | 1.931 | 0.03011 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8229 | 0.06985 | 0.7191 | 0.6447 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.477 | 0.9694 | 0.7592 | 1.797 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -11.15 | 0.05292 | 2.063 | 0.1800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4962 | -1.473 | -0.9311 | -1.912 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.287 | 0.8965 | 1.659 | -5.399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.766 | -0.2649 | -1.228 | -0.7899 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 113</span>| 467.14275 | 1.016 | -1.904 | -0.9201 | -0.7599 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9736 | -1.507 | 1.777 | -1.851 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8922 | -0.4826 | -0.8948 | -1.157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6182 | -0.8576 | -0.9943 | -0.3850 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.14275 | 92.43 | -6.104 | -0.8986 | -2.022 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.586 | 0.1725 | 1.931 | 0.03014 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8227 | 0.06984 | 0.7179 | 0.6470 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.478 | 0.9693 | 0.7594 | 1.799 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.14275</span> | 92.43 | 0.002233 | 0.2893 | 0.1324 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01019 | 0.5430 | 1.931 | 0.03014 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8227 | 0.06984 | 0.7179 | 0.6470 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.478 | 0.9693 | 0.7594 | 1.799 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -6.177 | 0.04590 | 2.051 | 0.1758 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4936 | -1.461 | -0.9893 | -1.828 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.266 | 0.7615 | 1.545 | -5.206 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.792 | -0.2512 | -1.220 | -0.7551 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 114</span>| 467.10820 | 1.017 | -1.905 | -0.9220 | -0.7605 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9724 | -1.505 | 1.777 | -1.849 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8932 | -0.4835 | -0.8976 | -1.151 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6164 | -0.8576 | -0.9935 | -0.3828 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.1082 | 92.55 | -6.105 | -0.9003 | -2.023 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.585 | 0.1737 | 1.930 | 0.03020 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8223 | 0.06981 | 0.7158 | 0.6522 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.480 | 0.9692 | 0.7601 | 1.802 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.1082</span> | 92.55 | 0.002232 | 0.2890 | 0.1323 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01020 | 0.5433 | 1.930 | 0.03020 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8223 | 0.06981 | 0.7158 | 0.6522 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.480 | 0.9692 | 0.7601 | 1.802 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 8.449 | 0.03092 | 2.044 | 0.1611 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4934 | -1.430 | -1.221 | -1.596 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.229 | 0.8691 | 1.875 | -2.123 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.605 | -0.2558 | -1.009 | -0.7122 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 115</span>| 467.10106 | 1.014 | -1.905 | -0.9236 | -0.7611 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9712 | -1.502 | 1.777 | -1.847 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8940 | -0.4849 | -0.9012 | -1.147 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6148 | -0.8578 | -0.9928 | -0.3803 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.10106 | 92.28 | -6.105 | -0.9017 | -2.023 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.584 | 0.1749 | 1.930 | 0.03026 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8220 | 0.06977 | 0.7132 | 0.6562 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.482 | 0.9690 | 0.7607 | 1.805 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.10106</span> | 92.28 | 0.002232 | 0.2887 | 0.1322 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01022 | 0.5436 | 1.930 | 0.03026 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8220 | 0.06977 | 0.7132 | 0.6562 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.482 | 0.9690 | 0.7607 | 1.805 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -24.17 | 0.001665 | 1.814 | 0.1960 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4738 | -1.444 | -0.8955 | -1.908 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.221 | 0.7910 | 1.755 | -3.560 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.244 | -0.2675 | -0.8607 | -0.7175 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 116</span>| 467.04630 | 1.016 | -1.905 | -0.9246 | -0.7619 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9696 | -1.499 | 1.777 | -1.845 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8944 | -0.4866 | -0.9055 | -1.143 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6133 | -0.8582 | -0.9923 | -0.3775 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.0463 | 92.45 | -6.105 | -0.9026 | -2.024 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.582 | 0.1762 | 1.930 | 0.03032 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8218 | 0.06972 | 0.7101 | 0.6601 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.484 | 0.9686 | 0.7611 | 1.808 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.0463</span> | 92.45 | 0.002231 | 0.2885 | 0.1321 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01023 | 0.5439 | 1.930 | 0.03032 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8218 | 0.06972 | 0.7101 | 0.6601 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.484 | 0.9686 | 0.7611 | 1.808 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.647 | -0.007887 | 1.876 | 0.1719 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4730 | -1.410 | -0.8701 | -1.589 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.184 | 0.7244 | 1.544 | -4.110 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.544 | -0.3120 | -0.9430 | -0.6527 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 117</span>| 467.02543 | 1.017 | -1.906 | -0.9263 | -0.7625 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9684 | -1.497 | 1.777 | -1.843 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8954 | -0.4879 | -0.9089 | -1.137 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6116 | -0.8583 | -0.9915 | -0.3753 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 467.02543 | 92.58 | -6.106 | -0.9041 | -2.025 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.581 | 0.1775 | 1.930 | 0.03038 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8214 | 0.06968 | 0.7076 | 0.6649 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.486 | 0.9686 | 0.7618 | 1.811 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 467.02543</span> | 92.58 | 0.002230 | 0.2882 | 0.1320 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01025 | 0.5443 | 1.930 | 0.03038 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8214 | 0.06968 | 0.7076 | 0.6649 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.486 | 0.9686 | 0.7618 | 1.811 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 12.94 | -0.02385 | 1.879 | 0.1542 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4735 | -1.378 | -0.8918 | -1.355 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.131 | 0.6590 | 1.631 | -3.618 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.430 | -0.2321 | -0.8462 | -0.6495 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 118</span>| 466.99646 | 1.016 | -1.906 | -0.9273 | -0.7632 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9670 | -1.494 | 1.776 | -1.841 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8958 | -0.4892 | -0.9132 | -1.133 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6101 | -0.8587 | -0.9911 | -0.3725 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.99646 | 92.42 | -6.106 | -0.9050 | -2.026 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.579 | 0.1788 | 1.930 | 0.03043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8212 | 0.06964 | 0.7044 | 0.6690 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.488 | 0.9682 | 0.7622 | 1.814 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.99646</span> | 92.42 | 0.002230 | 0.2880 | 0.1319 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01026 | 0.5446 | 1.930 | 0.03043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8212 | 0.06964 | 0.7044 | 0.6690 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.488 | 0.9682 | 0.7622 | 1.814 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.590 | -0.05004 | 1.738 | 0.1737 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4573 | -1.378 | -0.8791 | -1.534 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.117 | 0.8064 | 1.528 | -3.141 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8220 | 0.1296 | -0.3838 | -0.6246 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 119</span>| 466.97639 | 1.017 | -1.906 | -0.9282 | -0.7640 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9655 | -1.490 | 1.776 | -1.839 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8964 | -0.4910 | -0.9175 | -1.129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6092 | -0.8593 | -0.9910 | -0.3693 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.97639 | 92.52 | -6.106 | -0.9059 | -2.026 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.578 | 0.1803 | 1.930 | 0.03049 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8210 | 0.06959 | 0.7013 | 0.6726 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.489 | 0.9676 | 0.7623 | 1.818 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.97639</span> | 92.52 | 0.002230 | 0.2878 | 0.1318 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01028 | 0.5450 | 1.930 | 0.03049 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8210 | 0.06959 | 0.7013 | 0.6726 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.489 | 0.9676 | 0.7623 | 1.818 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 7.027 | -0.06281 | 1.755 | 0.1604 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4507 | -1.349 | -0.8053 | -1.299 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.095 | 0.6623 | 1.032 | -2.794 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8171 | 0.07286 | -0.3538 | -0.5889 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 120</span>| 466.96001 | 1.015 | -1.906 | -0.9299 | -0.7649 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9637 | -1.486 | 1.775 | -1.837 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8976 | -0.4931 | -0.9192 | -1.125 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6091 | -0.8600 | -0.9916 | -0.3657 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.96001 | 92.40 | -6.106 | -0.9074 | -2.027 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.576 | 0.1824 | 1.930 | 0.03055 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8205 | 0.06953 | 0.7000 | 0.6758 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.489 | 0.9669 | 0.7618 | 1.823 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.96001</span> | 92.40 | 0.002230 | 0.2875 | 0.1317 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01029 | 0.5455 | 1.930 | 0.03055 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8205 | 0.06953 | 0.7000 | 0.6758 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.489 | 0.9669 | 0.7618 | 1.823 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -7.315 | -0.08361 | 1.595 | 0.1755 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4289 | -1.331 | -0.8104 | -1.428 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.055 | 0.7710 | 1.242 | -2.826 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.346 | -0.3282 | -0.6399 | -0.5709 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 121</span>| 466.94053 | 1.016 | -1.905 | -0.9315 | -0.7662 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9617 | -1.480 | 1.774 | -1.835 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8987 | -0.4954 | -0.9193 | -1.121 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6079 | -0.8601 | -0.9919 | -0.3632 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.94053 | 92.48 | -6.105 | -0.9088 | -2.029 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.574 | 0.1849 | 1.929 | 0.03061 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8200 | 0.06946 | 0.6999 | 0.6792 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.490 | 0.9668 | 0.7615 | 1.826 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.94053</span> | 92.48 | 0.002231 | 0.2873 | 0.1315 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01031 | 0.5461 | 1.929 | 0.03061 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8200 | 0.06946 | 0.6999 | 0.6792 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.490 | 0.9668 | 0.7615 | 1.826 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.448 | -0.09452 | 1.578 | 0.1631 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4178 | -1.275 | -0.7880 | -1.291 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.013 | 0.7275 | 1.336 | -0.1176 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.297 | -0.2757 | -0.6338 | -0.5586 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 122</span>| 466.92529 | 1.015 | -1.905 | -0.9321 | -0.7676 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9593 | -1.476 | 1.775 | -1.833 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8992 | -0.4984 | -0.9232 | -1.122 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6063 | -0.8604 | -0.9916 | -0.3612 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.92529 | 92.34 | -6.105 | -0.9093 | -2.030 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.572 | 0.1871 | 1.930 | 0.03066 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8198 | 0.06938 | 0.6971 | 0.6791 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.492 | 0.9666 | 0.7618 | 1.828 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.92529</span> | 92.34 | 0.002233 | 0.2871 | 0.1313 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01034 | 0.5466 | 1.930 | 0.03066 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8198 | 0.06938 | 0.6971 | 0.6791 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.492 | 0.9666 | 0.7618 | 1.828 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -12.72 | -0.09950 | 1.479 | 0.1754 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4012 | -1.242 | -0.7866 | -1.413 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9668 | 0.6187 | 0.9349 | -2.630 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.260 | -0.3489 | -0.4063 | -0.5476 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 123</span>| 466.89942 | 1.016 | -1.904 | -0.9326 | -0.7693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9564 | -1.470 | 1.775 | -1.832 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8995 | -0.5006 | -0.9260 | -1.122 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6055 | -0.8609 | -0.9921 | -0.3587 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.89942 | 92.48 | -6.104 | -0.9097 | -2.032 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.569 | 0.1897 | 1.929 | 0.03069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8197 | 0.06931 | 0.6950 | 0.6788 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.493 | 0.9661 | 0.7614 | 1.831 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.89942</span> | 92.48 | 0.002235 | 0.2871 | 0.1311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01037 | 0.5473 | 1.929 | 0.03069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8197 | 0.06931 | 0.6950 | 0.6788 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.493 | 0.9661 | 0.7614 | 1.831 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.439 | -0.09008 | 1.544 | 0.1555 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3845 | -1.174 | -0.7709 | -1.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9305 | 0.6799 | 1.153 | -2.871 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.766 | -0.2963 | -0.5389 | -0.5305 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 124</span>| 466.87885 | 1.016 | -1.902 | -0.9335 | -0.7713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9544 | -1.465 | 1.775 | -1.831 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8988 | -0.5028 | -0.9291 | -1.120 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6025 | -0.8609 | -0.9918 | -0.3573 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.87885 | 92.42 | -6.102 | -0.9106 | -2.034 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.567 | 0.1922 | 1.930 | 0.03072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8200 | 0.06925 | 0.6928 | 0.6803 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.497 | 0.9661 | 0.7616 | 1.833 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.87885</span> | 92.42 | 0.002239 | 0.2869 | 0.1309 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01039 | 0.5479 | 1.930 | 0.03072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8200 | 0.06925 | 0.6928 | 0.6803 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.497 | 0.9661 | 0.7616 | 1.833 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.274 | -0.09794 | 1.477 | 0.1445 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3711 | -1.126 | -0.7697 | -1.253 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9213 | 0.5797 | 0.6929 | -2.254 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4364 | 0.05549 | -0.07007 | -0.5105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 125</span>| 466.87374 | 1.017 | -1.901 | -0.9363 | -0.7725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9523 | -1.459 | 1.775 | -1.829 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9004 | -0.5050 | -0.9284 | -1.119 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6029 | -0.8616 | -0.9930 | -0.3542 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.87374 | 92.57 | -6.101 | -0.9131 | -2.035 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.565 | 0.1945 | 1.929 | 0.03078 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8193 | 0.06919 | 0.6933 | 0.6817 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.496 | 0.9655 | 0.7605 | 1.836 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.87374</span> | 92.57 | 0.002241 | 0.2864 | 0.1307 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01041 | 0.5485 | 1.929 | 0.03078 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8193 | 0.06919 | 0.6933 | 0.6817 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.496 | 0.9655 | 0.7605 | 1.836 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 13.60 | -0.09484 | 1.445 | 0.1251 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3584 | -1.070 | -0.7354 | -1.048 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8551 | 0.6144 | 0.8824 | -0.009520 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4410 | 0.04024 | -0.2274 | -0.5153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 126</span>| 466.85547 | 1.016 | -1.900 | -0.9388 | -0.7737 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9500 | -1.454 | 1.774 | -1.828 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9020 | -0.5070 | -0.9271 | -1.119 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6040 | -0.8622 | -0.9946 | -0.3509 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.85547 | 92.42 | -6.100 | -0.9152 | -2.036 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.562 | 0.1970 | 1.929 | 0.03083 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8186 | 0.06913 | 0.6942 | 0.6818 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.495 | 0.9648 | 0.7592 | 1.841 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.85547</span> | 92.42 | 0.002243 | 0.2859 | 0.1305 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01044 | 0.5491 | 1.929 | 0.03083 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8186 | 0.06913 | 0.6942 | 0.6818 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.495 | 0.9648 | 0.7592 | 1.841 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.539 | -0.09755 | 1.262 | 0.1433 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3291 | -1.038 | -0.7482 | -1.225 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8087 | 0.5023 | 0.8171 | -0.005344 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4685 | 0.01356 | -0.1499 | -0.5112 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 127</span>| 466.84409 | 1.016 | -1.899 | -0.9408 | -0.7751 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9477 | -1.449 | 1.774 | -1.826 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9037 | -0.5088 | -0.9269 | -1.119 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6048 | -0.8630 | -0.9960 | -0.3473 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.84409 | 92.47 | -6.099 | -0.9171 | -2.037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.560 | 0.1996 | 1.929 | 0.03088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8179 | 0.06907 | 0.6944 | 0.6816 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.494 | 0.9641 | 0.7580 | 1.845 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.84409</span> | 92.47 | 0.002245 | 0.2856 | 0.1304 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01046 | 0.5497 | 1.929 | 0.03088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8179 | 0.06907 | 0.6944 | 0.6816 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.494 | 0.9641 | 0.7580 | 1.845 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.205 | -0.09489 | 1.201 | 0.1289 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3142 | -0.9889 | -0.7667 | -1.156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7401 | 0.5570 | 1.301 | -1.479 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.860 | -0.4540 | -0.5722 | -0.5005 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 128</span>| 466.83069 | 1.016 | -1.897 | -0.9405 | -0.7762 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9462 | -1.443 | 1.775 | -1.825 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9047 | -0.5101 | -0.9307 | -1.119 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6046 | -0.8636 | -0.9969 | -0.3435 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.83069 | 92.41 | -6.097 | -0.9168 | -2.039 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.559 | 0.2019 | 1.929 | 0.03091 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8175 | 0.06904 | 0.6917 | 0.6819 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.494 | 0.9635 | 0.7572 | 1.850 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.83069</span> | 92.41 | 0.002250 | 0.2856 | 0.1302 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01048 | 0.5503 | 1.929 | 0.03091 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8175 | 0.06904 | 0.6917 | 0.6819 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.494 | 0.9635 | 0.7572 | 1.850 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 129</span>| 466.81923 | 1.016 | -1.894 | -0.9398 | -0.7773 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9447 | -1.438 | 1.775 | -1.824 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9056 | -0.5113 | -0.9343 | -1.119 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6049 | -0.8643 | -0.9979 | -0.3395 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.81923 | 92.43 | -6.094 | -0.9162 | -2.040 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.557 | 0.2043 | 1.930 | 0.03094 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8171 | 0.06900 | 0.6890 | 0.6818 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.494 | 0.9628 | 0.7563 | 1.854 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.81923</span> | 92.43 | 0.002255 | 0.2857 | 0.1301 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01049 | 0.5509 | 1.930 | 0.03094 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8171 | 0.06900 | 0.6890 | 0.6818 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.494 | 0.9628 | 0.7563 | 1.854 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 130</span>| 466.78977 | 1.016 | -1.887 | -0.9376 | -0.7810 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9400 | -1.422 | 1.776 | -1.820 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9086 | -0.5153 | -0.9461 | -1.119 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6057 | -0.8666 | -1.001 | -0.3266 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.78977 | 92.47 | -6.087 | -0.9142 | -2.043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.552 | 0.2120 | 1.930 | 0.03105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8159 | 0.06889 | 0.6804 | 0.6815 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.493 | 0.9606 | 0.7533 | 1.870 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.78977</span> | 92.47 | 0.002272 | 0.2861 | 0.1296 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01054 | 0.5528 | 1.930 | 0.03105 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8159 | 0.06889 | 0.6804 | 0.6815 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.493 | 0.9606 | 0.7533 | 1.870 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 131</span>| 466.76586 | 1.017 | -1.875 | -0.9340 | -0.7871 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9321 | -1.394 | 1.779 | -1.814 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9134 | -0.5218 | -0.9656 | -1.119 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6071 | -0.8705 | -1.007 | -0.3052 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.76586 | 92.53 | -6.075 | -0.9110 | -2.049 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.545 | 0.2247 | 1.931 | 0.03121 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8139 | 0.06870 | 0.6661 | 0.6811 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.491 | 0.9569 | 0.7485 | 1.896 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.76586</span> | 92.53 | 0.002300 | 0.2868 | 0.1288 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01062 | 0.5559 | 1.931 | 0.03121 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8139 | 0.06870 | 0.6661 | 0.6811 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.491 | 0.9569 | 0.7485 | 1.896 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 10.71 | -0.05605 | 1.440 | 0.09508 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1459 | -0.5070 | -0.9907 | -0.8007 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4069 | 0.2923 | 0.01818 | -1.553 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.109 | -0.3306 | -0.3991 | -0.2309 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 132</span>| 466.72646 | 1.014 | -1.848 | -0.9815 | -0.8092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9160 | -1.342 | 1.783 | -1.808 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9032 | -0.5322 | -0.9570 | -1.117 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6032 | -0.8748 | -1.022 | -0.2748 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.72646 | 92.30 | -6.048 | -0.9533 | -2.072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.528 | 0.2483 | 1.933 | 0.03140 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8182 | 0.06840 | 0.6724 | 0.6828 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.496 | 0.9528 | 0.7357 | 1.933 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.72646</span> | 92.30 | 0.002362 | 0.2782 | 0.1260 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01080 | 0.5618 | 1.933 | 0.03140 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8182 | 0.06840 | 0.6724 | 0.6828 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.496 | 0.9528 | 0.7357 | 1.933 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -13.11 | -0.01237 | -0.5306 | 0.001870 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01074 | -0.001553 | -0.5011 | -1.124 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.5240 | 0.3999 | 0.1337 | 0.6209 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3667 | -0.5464 | -0.9326 | -0.1861 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 133</span>| 466.72714 | 1.014 | -1.830 | -0.9704 | -0.8250 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9153 | -1.342 | 1.791 | -1.785 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9449 | -0.5943 | -0.9266 | -1.116 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5962 | -0.8737 | -1.020 | -0.2698 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.72714 | 92.32 | -6.030 | -0.9434 | -2.087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.528 | 0.2486 | 1.936 | 0.03205 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8009 | 0.06660 | 0.6946 | 0.6846 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.504 | 0.9539 | 0.7372 | 1.939 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.72714</span> | 92.32 | 0.002405 | 0.2802 | 0.1240 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01081 | 0.5618 | 1.936 | 0.03205 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8009 | 0.06660 | 0.6946 | 0.6846 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.504 | 0.9539 | 0.7372 | 1.939 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 134</span>| 466.69721 | 1.015 | -1.839 | -0.9760 | -0.8170 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9156 | -1.342 | 1.787 | -1.797 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9238 | -0.5630 | -0.9420 | -1.117 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5997 | -0.8742 | -1.021 | -0.2723 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.69721 | 92.41 | -6.039 | -0.9484 | -2.079 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.528 | 0.2485 | 1.935 | 0.03173 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8096 | 0.06750 | 0.6834 | 0.6836 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.500 | 0.9534 | 0.7365 | 1.936 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.69721</span> | 92.41 | 0.002383 | 0.2792 | 0.1250 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01080 | 0.5618 | 1.935 | 0.03173 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8096 | 0.06750 | 0.6834 | 0.6836 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.500 | 0.9534 | 0.7365 | 1.936 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 0.5723 | 0.006769 | -0.2879 | -0.06332 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01114 | -0.03155 | -0.3915 | -0.7923 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3201 | -0.2330 | 0.8086 | -1.424 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3663 | -0.4815 | -0.7933 | -0.2384 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 135</span>| 466.73286 | 1.017 | -1.834 | -0.9731 | -0.8131 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9227 | -1.351 | 1.796 | -1.779 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9201 | -0.5595 | -0.9572 | -1.109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6142 | -0.8686 | -1.016 | -0.2440 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.73286 | 92.54 | -6.034 | -0.9458 | -2.075 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.535 | 0.2444 | 1.938 | 0.03223 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8111 | 0.06760 | 0.6723 | 0.6901 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.483 | 0.9587 | 0.7409 | 1.970 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.73286</span> | 92.54 | 0.002396 | 0.2797 | 0.1255 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01072 | 0.5608 | 1.938 | 0.03223 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8111 | 0.06760 | 0.6723 | 0.6901 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.483 | 0.9587 | 0.7409 | 1.970 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 136</span>| 466.69733 | 1.015 | -1.838 | -0.9750 | -0.8159 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9176 | -1.345 | 1.790 | -1.791 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9226 | -0.5619 | -0.9467 | -1.114 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6033 | -0.8723 | -1.019 | -0.2644 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.69733 | 92.40 | -6.038 | -0.9475 | -2.078 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.530 | 0.2474 | 1.936 | 0.03188 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8101 | 0.06754 | 0.6799 | 0.6863 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.496 | 0.9552 | 0.7382 | 1.945 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.69733</span> | 92.40 | 0.002386 | 0.2794 | 0.1251 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01078 | 0.5615 | 1.936 | 0.03188 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8101 | 0.06754 | 0.6799 | 0.6863 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.496 | 0.9552 | 0.7382 | 1.945 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 137</span>| 466.69584 | 1.015 | -1.839 | -0.9754 | -0.8165 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9164 | -1.343 | 1.788 | -1.794 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9231 | -0.5623 | -0.9445 | -1.114 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6009 | -0.8731 | -1.020 | -0.2689 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.69584 | 92.37 | -6.039 | -0.9478 | -2.079 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.529 | 0.2480 | 1.935 | 0.03180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8099 | 0.06752 | 0.6815 | 0.6857 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.499 | 0.9544 | 0.7377 | 1.940 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.69584</span> | 92.37 | 0.002384 | 0.2793 | 0.1251 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01079 | 0.5617 | 1.935 | 0.03180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8099 | 0.06752 | 0.6815 | 0.6857 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.499 | 0.9544 | 0.7377 | 1.940 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.069 | -0.001275 | -0.2861 | -0.04975 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01387 | -0.05203 | -0.3437 | -0.7173 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2694 | -0.1778 | 0.5026 | 0.8511 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9213 | -0.7376 | -0.9765 | -0.1682 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 138</span>| 466.68962 | 1.016 | -1.839 | -0.9764 | -0.8159 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9167 | -1.342 | 1.790 | -1.793 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9191 | -0.5597 | -0.9461 | -1.115 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6002 | -0.8712 | -1.018 | -0.2680 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.68962 | 92.46 | -6.039 | -0.9488 | -2.078 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.529 | 0.2485 | 1.936 | 0.03184 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8115 | 0.06760 | 0.6803 | 0.6854 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.499 | 0.9562 | 0.7392 | 1.941 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.68962</span> | 92.46 | 0.002385 | 0.2791 | 0.1251 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01079 | 0.5618 | 1.936 | 0.03184 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8115 | 0.06760 | 0.6803 | 0.6854 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.499 | 0.9562 | 0.7392 | 1.941 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 6.342 | 0.001592 | -0.2787 | -0.05882 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.004933 | -0.02534 | -0.4440 | -0.5467 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1484 | -0.03146 | 0.4648 | -1.264 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3607 | -0.2274 | -0.5157 | -0.1312 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 139</span>| 466.68314 | 1.015 | -1.839 | -0.9751 | -0.8151 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9166 | -1.339 | 1.792 | -1.792 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9160 | -0.5585 | -0.9470 | -1.115 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5998 | -0.8691 | -1.016 | -0.2676 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.68314 | 92.36 | -6.039 | -0.9476 | -2.077 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.529 | 0.2501 | 1.937 | 0.03187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8128 | 0.06763 | 0.6797 | 0.6853 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.500 | 0.9582 | 0.7404 | 1.942 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.68314</span> | 92.36 | 0.002385 | 0.2794 | 0.1252 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01079 | 0.5622 | 1.937 | 0.03187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8128 | 0.06763 | 0.6797 | 0.6853 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.500 | 0.9582 | 0.7404 | 1.942 |</span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.258 |-0.0003497 | -0.2788 | -0.03383 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01408 | 0.02647 | -0.2857 | -0.5956 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.05089 | 0.05050 | 0.4395 | 0.8187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2669 | -0.06868 | -0.3694 | -0.1159 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 140</span>| 466.67997 | 1.015 | -1.839 | -0.9739 | -0.8142 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9180 | -1.339 | 1.794 | -1.790 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9137 | -0.5623 | -0.9494 | -1.116 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6002 | -0.8690 | -1.016 | -0.2664 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.67997 | 92.38 | -6.039 | -0.9465 | -2.077 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.531 | 0.2499 | 1.938 | 0.03191 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8138 | 0.06752 | 0.6779 | 0.6846 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.499 | 0.9583 | 0.7410 | 1.943 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.67997</span> | 92.38 | 0.002385 | 0.2796 | 0.1254 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01078 | 0.5622 | 1.938 | 0.03191 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8138 | 0.06752 | 0.6779 | 0.6846 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.499 | 0.9583 | 0.7410 | 1.943 |</span> +<span class="r-out co"><span class="r-pr">#></span> | M| Mixed Diff. | -1.882 |-7.391e+04 | -0.2259 | -0.03295 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.005718 | 0.01130 | -0.3842 | -0.4930 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.04972 | -0.05953 | 0.5251 | -1.398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3564 | -0.08212 | -0.3242 | -0.1008 |</span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 141</span>| 466.67997 | 1.015 | -1.839 | -0.9739 | -0.8142 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9180 | -1.339 | 1.794 | -1.790 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9137 | -0.5623 | -0.9494 | -1.116 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6002 | -0.8690 | -1.016 | -0.2664 |</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 466.67997 | 92.38 | -6.039 | -0.9465 | -2.077 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.531 | 0.2499 | 1.938 | 0.03191 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8138 | 0.06752 | 0.6779 | 0.6846 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.499 | 0.9583 | 0.7410 | 1.943 |</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 466.67997</span> | 92.38 | 0.002385 | 0.2796 | 0.1254 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01078 | 0.5622 | 1.938 | 0.03191 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8138 | 0.06752 | 0.6779 | 0.6846 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.499 | 0.9583 | 0.7410 | 1.943 |</span> +<span class="r-out co"><span class="r-pr">#></span> calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>initial ETAs were nudged; (can control by foceiControl(etaNudge=., etaNudge2=))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>ETAs were reset to zero during optimization; (Can control by foceiControl(resetEtaP=.))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>using R matrix to calculate covariance, can check sandwich or S matrix with $covRS and $covS</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>gradient problems with initial estimate and covariance; see $scaleInfo</span> +<span class="r-in"></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">AIC</a></span><span class="op">(</span></span> +<span class="r-in"> <span class="va">f_nlmixr_sfo_sfo_focei_const</span><span class="op">$</span><span class="va">nm</span>,</span> +<span class="r-in"> <span class="va">f_nlmixr_fomc_sfo_focei_const</span><span class="op">$</span><span class="va">nm</span>,</span> +<span class="r-in"> <span class="va">f_nlmixr_dfop_sfo_focei_const</span><span class="op">$</span><span class="va">nm</span>,</span> +<span class="r-in"> <span class="va">f_nlmixr_fomc_sfo_saem_obs</span><span class="op">$</span><span class="va">nm</span>,</span> +<span class="r-in"> <span class="va">f_nlmixr_fomc_sfo_focei_obs</span><span class="op">$</span><span class="va">nm</span>,</span> +<span class="r-in"> <span class="va">f_nlmixr_dfop_sfo_saem_obs</span><span class="op">$</span><span class="va">nm</span>,</span> +<span class="r-in"> <span class="va">f_nlmixr_dfop_sfo_focei_obs</span><span class="op">$</span><span class="va">nm</span>,</span> +<span class="r-in"> <span class="va">f_nlmixr_fomc_sfo_focei_tc</span><span class="op">$</span><span class="va">nm</span>,</span> +<span class="r-in"> <span class="va">f_nlmixr_dfop_sfo_focei_tc</span><span class="op">$</span><span class="va">nm</span>,</span> +<span class="r-in"> <span class="va">f_nlmixr_fomc_sfo_saem_obs_tc</span><span class="op">$</span><span class="va">nm</span>,</span> +<span class="r-in"> <span class="va">f_nlmixr_fomc_sfo_focei_obs_tc</span><span class="op">$</span><span class="va">nm</span>,</span> +<span class="r-in"> <span class="va">f_nlmixr_dfop_sfo_saem_obs_tc</span><span class="op">$</span><span class="va">nm</span>,</span> +<span class="r-in"> <span class="va">f_nlmixr_dfop_sfo_focei_obs_tc</span><span class="op">$</span><span class="va">nm</span></span> +<span class="r-in"><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating -2LL by Gaussian quadrature (nnodes=3,nsd=1.6)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating -2LL by Gaussian quadrature (nnodes=3,nsd=1.6)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating -2LL by Gaussian quadrature (nnodes=3,nsd=1.6)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating -2LL by Gaussian quadrature (nnodes=3,nsd=1.6)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> df AIC</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_sfo_sfo_focei_const$nm 9 1082.4605</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_fomc_sfo_focei_const$nm 11 814.4261</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_dfop_sfo_focei_const$nm 13 870.2659</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_fomc_sfo_saem_obs$nm 12 788.8373</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_fomc_sfo_focei_obs$nm 12 794.5194</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_dfop_sfo_saem_obs$nm 14 815.0797</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_dfop_sfo_focei_obs$nm 14 834.8474</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_fomc_sfo_focei_tc$nm 12 812.3296</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_dfop_sfo_focei_tc$nm 14 819.4103</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_fomc_sfo_saem_obs_tc$nm 14 814.4248</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_fomc_sfo_focei_obs_tc$nm 14 787.4355</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_dfop_sfo_saem_obs_tc$nm 16 828.5143</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_dfop_sfo_focei_obs_tc$nm 16 811.1191</span> +<span class="r-in"><span class="co"># Currently, FOMC-SFO with two-component error by variable fitted by focei gives the</span></span> +<span class="r-in"><span class="co"># lowest AIC</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_nlmixr_fomc_sfo_focei_obs_tc</span><span class="op">)</span></span> +<span class="r-plt img"><img src="nlmixr.mmkin-2.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/summary.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">f_nlmixr_fomc_sfo_focei_obs_tc</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> nlmixr version used for fitting: 2.0.6 </span> +<span class="r-out co"><span class="r-pr">#></span> mkin version used for pre-fitting: 1.1.0 </span> +<span class="r-out co"><span class="r-pr">#></span> R version used for fitting: 4.1.2 </span> +<span class="r-out co"><span class="r-pr">#></span> Date of fit: Wed Mar 2 18:01:07 2022 </span> +<span class="r-out co"><span class="r-pr">#></span> Date of summary: Wed Mar 2 18:02:45 2022 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Equations:</span> +<span class="r-out co"><span class="r-pr">#></span> d_parent/dt = - (alpha/beta) * 1/((time/beta) + 1) * parent</span> +<span class="r-out co"><span class="r-pr">#></span> d_A1/dt = + f_parent_to_A1 * (alpha/beta) * 1/((time/beta) + 1) *</span> +<span class="r-out co"><span class="r-pr">#></span> parent - k_A1 * A1</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Data:</span> +<span class="r-out co"><span class="r-pr">#></span> 170 observations of 2 variable(s) grouped in 5 datasets</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Degradation model predictions using RxODE</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fitted in 17.315 s</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Variance model: Two-component variance unique to each observed variable </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Mean of starting values for individual parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_k_A1 f_parent_qlogis log_alpha log_beta </span> +<span class="r-out co"><span class="r-pr">#></span> 93.1168 -5.3034 -0.9442 -0.1065 2.2909 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Mean of starting values for error model parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low_parent rsd_high_parent sigma_low_A1 rsd_high_A1 </span> +<span class="r-out co"><span class="r-pr">#></span> 1.15958 0.03005 1.15958 0.03005 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fixed degradation parameter values:</span> +<span class="r-out co"><span class="r-pr">#></span> None</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Results:</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Likelihood calculated by focei </span> +<span class="r-out co"><span class="r-pr">#></span> AIC BIC logLik</span> +<span class="r-out co"><span class="r-pr">#></span> 787.4 831.3 -379.7</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Optimised parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> est. lower upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 93.6717 91.2552 96.0882</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_A1 -6.3199 -8.4468 -4.1930</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_qlogis -1.0089 -1.3823 -0.6356</span> +<span class="r-out co"><span class="r-pr">#></span> log_alpha -0.1616 -0.6624 0.3392</span> +<span class="r-out co"><span class="r-pr">#></span> log_beta 2.2088 1.6800 2.7376</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Correlation: </span> +<span class="r-out co"><span class="r-pr">#></span> parnt_0 lg_k_A1 f_prnt_ log_lph</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_A1 0.3717 </span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_qlogis -0.7856 -0.4088 </span> +<span class="r-out co"><span class="r-pr">#></span> log_alpha 0.3361 0.9419 -0.3063 </span> +<span class="r-out co"><span class="r-pr">#></span> log_beta -0.3985 -0.7595 0.2484 -0.5549</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Random effects (omega):</span> +<span class="r-out co"><span class="r-pr">#></span> eta.parent_0 eta.log_k_A1 eta.f_parent_qlogis eta.log_alpha</span> +<span class="r-out co"><span class="r-pr">#></span> eta.parent_0 4.391 0.000 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_A1 0.000 6.402 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_parent_qlogis 0.000 0.000 0.1584 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_alpha 0.000 0.000 0.0000 0.3381</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_beta 0.000 0.000 0.0000 0.0000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_beta</span> +<span class="r-out co"><span class="r-pr">#></span> eta.parent_0 0.000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_A1 0.000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_parent_qlogis 0.000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_alpha 0.000</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_beta 0.358</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Variance model:</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_low_parent rsd_high_parent sigma_low_A1 rsd_high_A1 </span> +<span class="r-out co"><span class="r-pr">#></span> 2.35616 0.00153 0.63564 0.08639 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Backtransformed parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> est. lower upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 93.6717 9.126e+01 96.0882</span> +<span class="r-out co"><span class="r-pr">#></span> k_A1 0.0018 2.146e-04 0.0151</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_A1 0.2672 2.006e-01 0.3462</span> +<span class="r-out co"><span class="r-pr">#></span> alpha 0.8508 5.156e-01 1.4038</span> +<span class="r-out co"><span class="r-pr">#></span> beta 9.1049 5.366e+00 15.4499</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Resulting formation fractions:</span> +<span class="r-out co"><span class="r-pr">#></span> ff</span> +<span class="r-out co"><span class="r-pr">#></span> parent_A1 0.2672</span> +<span class="r-out co"><span class="r-pr">#></span> parent_sink 0.7328</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Estimated disappearance times:</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90 DT50back</span> +<span class="r-out co"><span class="r-pr">#></span> parent 11.46 127.3 38.31</span> +<span class="r-out co"><span class="r-pr">#></span> A1 385.05 1279.1 NA</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Two parallel metabolites</span></span> +<span class="r-in"><span class="va">dmta_ds</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="fl">1</span><span class="op">:</span><span class="fl">7</span>, <span class="kw">function</span><span class="op">(</span><span class="va">i</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="va">ds_i</span> <span class="op"><-</span> <span class="va">dimethenamid_2018</span><span class="op">$</span><span class="va">ds</span><span class="op">[[</span><span class="va">i</span><span class="op">]</span><span class="op">]</span><span class="op">$</span><span class="va">data</span></span> +<span class="r-in"> <span class="va">ds_i</span><span class="op">[</span><span class="va">ds_i</span><span class="op">$</span><span class="va">name</span> <span class="op">==</span> <span class="st">"DMTAP"</span>, <span class="st">"name"</span><span class="op">]</span> <span class="op"><-</span> <span class="st">"DMTA"</span></span> +<span class="r-in"> <span class="va">ds_i</span><span class="op">$</span><span class="va">time</span> <span class="op"><-</span> <span class="va">ds_i</span><span class="op">$</span><span class="va">time</span> <span class="op">*</span> <span class="va">dimethenamid_2018</span><span class="op">$</span><span class="va">f_time_norm</span><span class="op">[</span><span class="va">i</span><span class="op">]</span></span> +<span class="r-in"> <span class="va">ds_i</span></span> +<span class="r-in"><span class="op">}</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">dmta_ds</span><span class="op">)</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">sapply</a></span><span class="op">(</span><span class="va">dimethenamid_2018</span><span class="op">$</span><span class="va">ds</span>, <span class="kw">function</span><span class="op">(</span><span class="va">ds</span><span class="op">)</span> <span class="va">ds</span><span class="op">$</span><span class="va">title</span><span class="op">)</span></span> +<span class="r-in"><span class="va">dmta_ds</span><span class="op">[[</span><span class="st">"Elliot"</span><span class="op">]</span><span class="op">]</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/cbind.html" class="external-link">rbind</a></span><span class="op">(</span><span class="va">dmta_ds</span><span class="op">[[</span><span class="st">"Elliot 1"</span><span class="op">]</span><span class="op">]</span>, <span class="va">dmta_ds</span><span class="op">[[</span><span class="st">"Elliot 2"</span><span class="op">]</span><span class="op">]</span><span class="op">)</span></span> +<span class="r-in"><span class="va">dmta_ds</span><span class="op">[[</span><span class="st">"Elliot 1"</span><span class="op">]</span><span class="op">]</span> <span class="op"><-</span> <span class="cn">NULL</span></span> +<span class="r-in"><span class="va">dmta_ds</span><span class="op">[[</span><span class="st">"Elliot 2"</span><span class="op">]</span><span class="op">]</span> <span class="op"><-</span> <span class="cn">NULL</span></span> +<span class="r-in"><span class="va">sfo_sfo2</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> DMTA <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"M23"</span>, <span class="st">"M27"</span><span class="op">)</span><span class="op">)</span>,</span> +<span class="r-in"> M23 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> M27 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> quiet <span class="op">=</span> <span class="cn">TRUE</span></span> +<span class="r-in"><span class="op">)</span></span> +<span class="r-in"><span class="va">f_dmta_sfo_sfo2</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="st">"SFO-SFO2"</span> <span class="op">=</span> <span class="va">sfo_sfo2</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">dmta_ds</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"obs"</span><span class="op">)</span></span> +<span class="r-in"><span class="fu">nlmixr_model</span><span class="op">(</span><span class="va">f_dmta_sfo_sfo2</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> function () </span> +<span class="r-out co"><span class="r-pr">#></span> {</span> +<span class="r-out co"><span class="r-pr">#></span> ini({</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_0 = 97</span> +<span class="r-out co"><span class="r-pr">#></span> eta.DMTA_0 ~ 2</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_DMTA = -2.9</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_DMTA ~ 0.66</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M23 = -3.8</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M23 ~ 0.52</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M27 = -5.7</span> +<span class="r-out co"><span class="r-pr">#></span> eta.log_k_M27 ~ 2</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_1_qlogis = -2.1</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_1_qlogis ~ 0.3</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_2_qlogis = -2</span> +<span class="r-out co"><span class="r-pr">#></span> eta.f_DMTA_tffm0_2_qlogis ~ 0.3</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_DMTA = 2.1</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_M23 = 0.71</span> +<span class="r-out co"><span class="r-pr">#></span> sigma_M27 = 0.56</span> +<span class="r-out co"><span class="r-pr">#></span> })</span> +<span class="r-out co"><span class="r-pr">#></span> model({</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA_0_model = DMTA_0 + eta.DMTA_0</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA(0) = DMTA_0_model</span> +<span class="r-out co"><span class="r-pr">#></span> k_DMTA = exp(log_k_DMTA + eta.log_k_DMTA)</span> +<span class="r-out co"><span class="r-pr">#></span> k_M23 = exp(log_k_M23 + eta.log_k_M23)</span> +<span class="r-out co"><span class="r-pr">#></span> k_M27 = exp(log_k_M27 + eta.log_k_M27)</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_1 = expit(f_DMTA_tffm0_1_qlogis + eta.f_DMTA_tffm0_1_qlogis)</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_tffm0_2 = expit(f_DMTA_tffm0_2_qlogis + eta.f_DMTA_tffm0_2_qlogis)</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_to_M23 = f_DMTA_tffm0_1</span> +<span class="r-out co"><span class="r-pr">#></span> f_DMTA_to_M27 = f_DMTA_tffm0_2 * (1 - f_DMTA_tffm0_1)</span> +<span class="r-out co"><span class="r-pr">#></span> d/dt(DMTA) = -k_DMTA * DMTA</span> +<span class="r-out co"><span class="r-pr">#></span> d/dt(M23) = +f_DMTA_to_M23 * k_DMTA * DMTA - k_M23 * </span> +<span class="r-out co"><span class="r-pr">#></span> M23</span> +<span class="r-out co"><span class="r-pr">#></span> d/dt(M27) = +f_DMTA_to_M27 * k_DMTA * DMTA - k_M27 * </span> +<span class="r-out co"><span class="r-pr">#></span> M27</span> +<span class="r-out co"><span class="r-pr">#></span> DMTA ~ add(sigma_DMTA)</span> +<span class="r-out co"><span class="r-pr">#></span> M23 ~ add(sigma_M23)</span> +<span class="r-out co"><span class="r-pr">#></span> M27 ~ add(sigma_M27)</span> +<span class="r-out co"><span class="r-pr">#></span> })</span> +<span class="r-out co"><span class="r-pr">#></span> }</span> +<span class="r-out co"><span class="r-pr">#></span> <environment: 0x555564ac3818></span> +<span class="r-in"><span class="va">nlmixr_focei_dmta_sfo_sfo2</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_dmta_sfo_sfo2</span>, est <span class="op">=</span> <span class="st">"focei"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="font-weight: bold;">Key:</span> U: Unscaled Parameters; X: Back-transformed parameters; G: Gill difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> F: Forward difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> C: Central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> M: Mixed forward and central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> Unscaled parameters for Omegas=chol(solve(omega));</span> +<span class="r-out co"><span class="r-pr">#></span> Diagonals are transformed, as specified by foceiControl(diagXform=)</span> +<span class="r-out co"><span class="r-pr">#></span> |-----+---------------+-----------+-----------+-----------+-----------|</span> +<span class="r-out co"><span class="r-pr">#></span> | #| Objective Fun | DMTA_0 |log_k_DMTA | log_k_M23 | log_k_M27 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................|f_DMTA_tffm0_1_qlogis |f_DMTA_tffm0_2_qlogis |sigma_DMTA | sigma_M23 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| sigma_M27 | o1 | o2 | o3 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| o4 | o5 | o6 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 1</span>| 833.04051 | 1.000 | -0.9455 | -0.9630 | -1.000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9299 | -0.9279 | -0.8481 | -0.8752 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8781 | -0.8726 | -0.8674 | -0.8661 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8726 | -0.8627 | -0.8627 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 833.04051 | 97.00 | -2.900 | -3.800 | -5.700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.100 | -2.000 | 2.100 | 0.7100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.5600 | 0.8409 | 1.109 | 1.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8409 | 1.351 | 1.351 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 833.04051</span> | 97.00 | 0.05502 | 0.02237 | 0.003346 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1091 | 0.1192 | 2.100 | 0.7100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.5600 | 0.8409 | 1.109 | 1.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8409 | 1.351 | 1.351 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | G| Gill Diff. | 6.064 | -0.2569 | 9.159 | -2.987 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -5.463 | 1.428 | -91.01 | -64.30 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -105.9 | 2.473 | -10.56 | 26.93 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.864 | -10.73 | -1.863 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 2</span>| 790.03872 | 0.9615 | -0.9438 | -1.021 | -0.9810 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8952 | -0.9370 | -0.2698 | -0.4666 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2051 | -0.8883 | -0.8003 | -1.037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8544 | -0.7945 | -0.8508 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 790.03872 | 93.26 | -2.898 | -3.858 | -5.681 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.027 | -2.018 | 2.707 | 0.8550 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7484 | 0.8277 | 1.184 | 0.9761 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8562 | 1.443 | 1.367 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 790.03872</span> | 93.26 | 0.05511 | 0.02111 | 0.003410 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1164 | 0.1173 | 2.707 | 0.8550 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7484 | 0.8277 | 1.184 | 0.9761 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8562 | 1.443 | 1.367 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1203. | 0.1766 | 3.828 | -3.699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.277 | -3.309 | -7.028 | -3.626 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.785 | 54.50 | -5.905 | 3.230 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -3.377 | -8.165 | -1.842 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 3</span>| 1615.1823 | 1.259 | -0.9424 | -1.076 | -0.9624 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8623 | -0.9445 | 0.2695 | -0.08596 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4207 | -0.9180 | -0.7364 | -1.197 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8366 | -0.7289 | -0.8393 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 1615.1823 | 122.1 | -2.897 | -3.913 | -5.662 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.958 | -2.033 | 3.274 | 0.9902 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9237 | 0.8027 | 1.255 | 0.7875 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8712 | 1.532 | 1.383 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 1615.1823</span> | 122.1 | 0.05519 | 0.01997 | 0.003474 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1237 | 0.1158 | 3.274 | 0.9902 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9237 | 0.8027 | 1.255 | 0.7875 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8712 | 1.532 | 1.383 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 4</span>| 959.79005 | 1.112 | -0.9439 | -1.022 | -0.9806 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8949 | -0.9366 | -0.2689 | -0.4661 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2049 | -0.8952 | -0.7996 | -1.038 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8540 | -0.7935 | -0.8506 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 959.79005 | 107.9 | -2.898 | -3.859 | -5.681 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.027 | -2.017 | 2.708 | 0.8552 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7485 | 0.8219 | 1.185 | 0.9756 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8566 | 1.445 | 1.368 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 959.79005</span> | 107.9 | 0.05511 | 0.02110 | 0.003412 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1164 | 0.1174 | 2.708 | 0.8552 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7485 | 0.8219 | 1.185 | 0.9756 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8566 | 1.445 | 1.368 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 5</span>| 766.97120 | 1.000 | -0.9438 | -1.021 | -0.9809 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8951 | -0.9369 | -0.2695 | -0.4665 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2050 | -0.8901 | -0.8001 | -1.037 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8543 | -0.7943 | -0.8508 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 766.9712 | 97.04 | -2.898 | -3.858 | -5.681 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.027 | -2.018 | 2.707 | 0.8551 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7485 | 0.8262 | 1.184 | 0.9760 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8563 | 1.444 | 1.367 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 766.9712</span> | 97.04 | 0.05511 | 0.02110 | 0.003410 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1164 | 0.1173 | 2.707 | 0.8551 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7485 | 0.8262 | 1.184 | 0.9760 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8563 | 1.444 | 1.367 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 17.19 | -0.3226 | 4.073 | -3.551 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.344 | -0.4208 | 1.861 | -4.402 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -3.892 | -0.6542 | -5.926 | 4.557 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -3.217 | -8.034 | -1.874 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 6</span>| 766.81060 | 0.9993 | -0.9437 | -1.024 | -0.9793 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8941 | -0.9371 | -0.2482 | -0.4501 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1789 | -0.8907 | -0.7962 | -1.045 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8529 | -0.7898 | -0.8499 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 766.8106 | 96.93 | -2.898 | -3.861 | -5.679 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.025 | -2.018 | 2.730 | 0.8609 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7558 | 0.8257 | 1.188 | 0.9671 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8575 | 1.450 | 1.368 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 766.8106</span> | 96.93 | 0.05512 | 0.02104 | 0.003416 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1166 | 0.1173 | 2.730 | 0.8609 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7558 | 0.8257 | 1.188 | 0.9671 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8575 | 1.450 | 1.368 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -15.39 | -0.3115 | 3.911 | -3.585 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.518 | -0.5604 | 3.636 | -2.887 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.137 | -0.8386 | -5.861 | 3.544 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -3.178 | -7.806 | -1.844 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 7</span>| 766.54512 | 1.003 | -0.9428 | -1.036 | -0.9690 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8990 | -0.9355 | -0.2617 | -0.4439 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1747 | -0.8835 | -0.7794 | -1.053 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8438 | -0.7677 | -0.8446 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 766.54512 | 97.33 | -2.897 | -3.873 | -5.669 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.035 | -2.015 | 2.716 | 0.8631 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7570 | 0.8318 | 1.207 | 0.9569 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8651 | 1.479 | 1.376 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 766.54512</span> | 97.33 | 0.05517 | 0.02081 | 0.003451 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1156 | 0.1176 | 2.716 | 0.8631 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7570 | 0.8318 | 1.207 | 0.9569 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8651 | 1.479 | 1.376 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 111.5 | -0.3718 | 3.702 | -3.687 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8687 | -0.06529 | 3.022 | -2.224 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.821 | 0.2102 | -4.533 | 2.766 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.768 | -6.628 | -1.505 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 8</span>| 766.09473 | 0.9987 | -0.9419 | -1.044 | -0.9594 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9033 | -0.9340 | -0.2855 | -0.4478 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1861 | -0.8834 | -0.7664 | -1.057 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8361 | -0.7496 | -0.8403 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 766.09473 | 96.88 | -2.896 | -3.881 | -5.659 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.044 | -2.012 | 2.691 | 0.8617 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7538 | 0.8318 | 1.221 | 0.9529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8716 | 1.504 | 1.381 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 766.09473</span> | 96.88 | 0.05522 | 0.02062 | 0.003485 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1146 | 0.1179 | 2.691 | 0.8617 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7538 | 0.8318 | 1.221 | 0.9529 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8716 | 1.504 | 1.381 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -37.62 | -0.3039 | 3.548 | -3.796 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7130 | -0.2251 | 0.3449 | -2.743 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.783 | -0.4584 | -3.845 | 2.208 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.677 | -5.610 | -1.259 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 9</span>| 765.84632 | 1.001 | -0.9407 | -1.057 | -0.9442 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9020 | -0.9332 | -0.3051 | -0.4515 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1945 | -0.8828 | -0.7538 | -1.058 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8263 | -0.7302 | -0.8359 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 765.84632 | 97.08 | -2.895 | -3.894 | -5.644 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -2.011 | 2.670 | 0.8604 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7514 | 0.8324 | 1.235 | 0.9520 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8799 | 1.530 | 1.387 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 765.84632</span> | 97.08 | 0.05529 | 0.02037 | 0.003538 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1181 | 2.670 | 0.8604 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7514 | 0.8324 | 1.235 | 0.9520 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8799 | 1.530 | 1.387 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 27.16 | -0.3150 | 3.428 | -3.883 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2016 | -0.01587 | -0.9475 | -2.944 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -3.512 | -0.2026 | -2.920 | 2.169 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.296 | -4.549 | -0.9950 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 10</span>| 765.58952 | 0.9994 | -0.9389 | -1.074 | -0.9188 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8956 | -0.9340 | -0.2957 | -0.4491 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1815 | -0.8759 | -0.7498 | -1.052 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8170 | -0.7204 | -0.8341 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 765.58952 | 96.94 | -2.893 | -3.911 | -5.619 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.028 | -2.012 | 2.680 | 0.8613 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7550 | 0.8382 | 1.240 | 0.9583 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8877 | 1.543 | 1.390 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 765.58952</span> | 96.94 | 0.05539 | 0.02003 | 0.003629 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1163 | 0.1179 | 2.680 | 0.8613 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7550 | 0.8382 | 1.240 | 0.9583 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8877 | 1.543 | 1.390 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 11</span>| 765.32464 | 0.9995 | -0.9365 | -1.096 | -0.8851 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8870 | -0.9350 | -0.2832 | -0.4460 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1644 | -0.8666 | -0.7446 | -1.045 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8047 | -0.7076 | -0.8318 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 765.32464 | 96.95 | -2.891 | -3.933 | -5.585 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.010 | -2.014 | 2.693 | 0.8623 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7598 | 0.8459 | 1.246 | 0.9668 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8980 | 1.561 | 1.393 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 765.32464</span> | 96.95 | 0.05552 | 0.01958 | 0.003753 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1182 | 0.1177 | 2.693 | 0.8623 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7598 | 0.8459 | 1.246 | 0.9668 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.8980 | 1.561 | 1.393 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -12.84 | -0.1780 | 3.152 | -3.943 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.881 | -0.7435 | 0.7708 | -2.561 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.120 | 0.1753 | -2.364 | 2.891 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.893 | -3.031 | -0.9792 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 12</span>| 764.89127 | 1.001 | -0.9331 | -1.138 | -0.8186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9173 | -0.9304 | -0.2709 | -0.4365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1500 | -0.8575 | -0.7404 | -1.047 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7849 | -0.6971 | -0.8273 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 764.89127 | 97.05 | -2.888 | -3.975 | -5.519 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.073 | -2.005 | 2.706 | 0.8657 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7639 | 0.8536 | 1.250 | 0.9649 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9146 | 1.575 | 1.399 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 764.89127</span> | 97.05 | 0.05571 | 0.01878 | 0.004011 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1117 | 0.1187 | 2.706 | 0.8657 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7639 | 0.8536 | 1.250 | 0.9649 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9146 | 1.575 | 1.399 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 19.26 | -0.1091 | 2.782 | -3.871 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -5.068 | -0.03848 | 1.779 | -1.635 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5035 | 0.4763 | -2.083 | 2.396 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.295 | -2.519 | -0.9166 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 13</span>| 764.86909 | 0.9949 | -0.9319 | -1.178 | -0.7471 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9138 | -0.9236 | -0.2803 | -0.4250 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1592 | -0.8601 | -0.7408 | -1.068 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7627 | -0.7028 | -0.8216 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 764.86909 | 96.51 | -2.886 | -4.015 | -5.447 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.066 | -1.991 | 2.696 | 0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7613 | 0.8514 | 1.250 | 0.9401 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9333 | 1.567 | 1.407 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 764.86909</span> | 96.51 | 0.05578 | 0.01803 | 0.004309 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1124 | 0.1201 | 2.696 | 0.8698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7613 | 0.8514 | 1.250 | 0.9401 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9333 | 1.567 | 1.407 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -169.3 | 0.02233 | 2.185 | -3.786 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.443 | 0.4519 | 0.3349 | -0.6672 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.014 | 1.036 | -2.128 | -0.1909 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.017 | -2.598 | -0.8552 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 14</span>| 764.27620 | 1.001 | -0.9315 | -1.198 | -0.7106 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9112 | -0.9215 | -0.2834 | -0.4198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1627 | -0.8638 | -0.7423 | -1.077 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7523 | -0.7079 | -0.8190 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 764.2762 | 97.07 | -2.886 | -4.035 | -5.411 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.061 | -1.987 | 2.693 | 0.8716 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7603 | 0.8483 | 1.248 | 0.9297 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9421 | 1.560 | 1.410 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 764.2762</span> | 97.07 | 0.05580 | 0.01769 | 0.004469 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1130 | 0.1206 | 2.693 | 0.8716 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7603 | 0.8483 | 1.248 | 0.9297 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9421 | 1.560 | 1.410 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 26.99 | -0.06591 | 1.982 | -3.655 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.737 | 1.224 | 0.5238 | -0.1462 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.477 | 0.3446 | -2.258 | -1.151 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.063 | -3.016 | -0.8065 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 15</span>| 764.08600 | 0.9998 | -0.9318 | -1.216 | -0.6718 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9105 | -0.9239 | -0.2868 | -0.4186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1661 | -0.8701 | -0.7420 | -1.077 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7408 | -0.7119 | -0.8158 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 764.086 | 96.98 | -2.886 | -4.053 | -5.372 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.059 | -1.992 | 2.689 | 0.8721 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7594 | 0.8430 | 1.249 | 0.9293 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9517 | 1.555 | 1.415 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 764.086</span> | 96.98 | 0.05578 | 0.01738 | 0.004646 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1131 | 0.1201 | 2.689 | 0.8721 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7594 | 0.8430 | 1.249 | 0.9293 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9517 | 1.555 | 1.415 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 16</span>| 763.68333 | 0.9997 | -0.9325 | -1.262 | -0.5698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9089 | -0.9302 | -0.2957 | -0.4154 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1752 | -0.8867 | -0.7413 | -1.078 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7108 | -0.7228 | -0.8074 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 763.68333 | 96.97 | -2.887 | -4.099 | -5.270 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.056 | -2.004 | 2.680 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7568 | 0.8290 | 1.249 | 0.9281 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9770 | 1.540 | 1.426 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 763.68333</span> | 96.97 | 0.05574 | 0.01659 | 0.005145 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1134 | 0.1187 | 2.680 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7568 | 0.8290 | 1.249 | 0.9281 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.9770 | 1.540 | 1.426 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 17</span>| 763.23003 | 0.9993 | -0.9340 | -1.363 | -0.3486 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9055 | -0.9438 | -0.3150 | -0.4083 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1949 | -0.9227 | -0.7397 | -1.080 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6457 | -0.7464 | -0.7892 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 763.23003 | 96.93 | -2.889 | -4.200 | -5.049 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.049 | -2.032 | 2.660 | 0.8757 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7513 | 0.7988 | 1.251 | 0.9256 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.032 | 1.508 | 1.451 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 763.23003</span> | 96.93 | 0.05566 | 0.01500 | 0.006419 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1142 | 0.1159 | 2.660 | 0.8757 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7513 | 0.7988 | 1.251 | 0.9256 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.032 | 1.508 | 1.451 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -22.00 | -0.1117 | 0.5708 | -1.597 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5912 | -4.959 | -1.502 | 1.095 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.055 | -1.786 | -1.932 | -2.056 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -2.026 | -5.307 | 0.1331 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 18</span>| 765.10598 | 0.9988 | -0.9419 | -1.481 | -0.006130 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9009 | -0.7845 | -0.3455 | -0.4625 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1991 | -0.9538 | -0.7488 | -1.046 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5215 | -0.7432 | -0.7830 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 765.10598 | 96.88 | -2.896 | -4.318 | -4.706 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.039 | -1.713 | 2.628 | 0.8565 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7501 | 0.7726 | 1.241 | 0.9658 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.136 | 1.513 | 1.459 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 765.10598</span> | 96.88 | 0.05522 | 0.01333 | 0.009040 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1152 | 0.1528 | 2.628 | 0.8565 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7501 | 0.7726 | 1.241 | 0.9658 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.136 | 1.513 | 1.459 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 19</span>| 763.02578 | 0.9999 | -0.9358 | -1.391 | -0.2684 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9044 | -0.9064 | -0.3221 | -0.4211 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1957 | -0.9299 | -0.7418 | -1.072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6165 | -0.7455 | -0.7877 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 763.02578 | 96.99 | -2.890 | -4.228 | -4.968 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.046 | -1.957 | 2.652 | 0.8712 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7511 | 0.7927 | 1.249 | 0.9351 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.056 | 1.510 | 1.452 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 763.02578</span> | 96.99 | 0.05556 | 0.01459 | 0.006954 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1144 | 0.1238 | 2.652 | 0.8712 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7511 | 0.7927 | 1.249 | 0.9351 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.056 | 1.510 | 1.452 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.557 | -0.1614 | 0.3205 | -0.9685 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3267 | 2.395 | -2.389 | -0.1069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.595 | -2.113 | -2.097 | -1.406 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.821 | -5.218 | -0.7119 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 20</span>| 766.17797 | 1.015 | -0.9359 | -1.390 | -0.2436 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9043 | -0.9341 | -0.3009 | -0.4312 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1485 | -0.9049 | -0.7235 | -1.053 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5884 | -0.6890 | -0.7788 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 766.17797 | 98.50 | -2.890 | -4.227 | -4.944 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.046 | -2.012 | 2.675 | 0.8676 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7643 | 0.8138 | 1.269 | 0.9575 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.080 | 1.586 | 1.465 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 766.17797</span> | 98.50 | 0.05555 | 0.01460 | 0.007129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1144 | 0.1179 | 2.675 | 0.8676 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7643 | 0.8138 | 1.269 | 0.9575 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.080 | 1.586 | 1.465 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 21</span>| 762.99023 | 1.002 | -0.9356 | -1.391 | -0.2672 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9040 | -0.9092 | -0.3192 | -0.4209 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1902 | -0.9274 | -0.7393 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6144 | -0.7393 | -0.7869 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.99023 | 97.17 | -2.890 | -4.228 | -4.967 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.046 | -1.963 | 2.655 | 0.8713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7526 | 0.7948 | 1.252 | 0.9371 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.058 | 1.518 | 1.454 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.99023</span> | 97.17 | 0.05557 | 0.01458 | 0.006962 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1145 | 0.1232 | 2.655 | 0.8713 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7526 | 0.7948 | 1.252 | 0.9371 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.058 | 1.518 | 1.454 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 51.43 | -0.1841 | 0.3204 | -0.9603 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07939 | 1.931 | -1.965 | -0.1875 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.362 | -1.812 | -1.918 | -2.236 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.746 | -4.882 | -0.6715 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 22</span>| 762.91633 | 1.000 | -0.9363 | -1.389 | -0.2610 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9054 | -0.9109 | -0.3206 | -0.4247 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1891 | -0.9263 | -0.7404 | -1.066 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6100 | -0.7370 | -0.7858 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.91633 | 97.00 | -2.891 | -4.226 | -4.961 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.049 | -1.966 | 2.654 | 0.8699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7529 | 0.7958 | 1.250 | 0.9417 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.062 | 1.521 | 1.455 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.91633</span> | 97.00 | 0.05553 | 0.01461 | 0.007006 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1142 | 0.1228 | 2.654 | 0.8699 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7529 | 0.7958 | 1.250 | 0.9417 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.062 | 1.521 | 1.455 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.4218 | -0.1782 | 0.3230 | -0.9273 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6605 | 1.389 | -2.249 | -0.4385 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -3.981 | -1.888 | -1.963 | -0.6447 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.620 | -4.721 | -0.6578 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 23</span>| 762.84890 | 1.001 | -0.9361 | -1.390 | -0.2598 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9045 | -0.9128 | -0.3175 | -0.4241 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1836 | -0.9236 | -0.7377 | -1.066 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6077 | -0.7305 | -0.7849 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.8489 | 97.05 | -2.891 | -4.227 | -4.960 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.047 | -1.970 | 2.657 | 0.8701 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7544 | 0.7980 | 1.253 | 0.9427 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.064 | 1.530 | 1.456 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.8489</span> | 97.05 | 0.05554 | 0.01460 | 0.007015 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1144 | 0.1224 | 2.657 | 0.8701 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7544 | 0.7980 | 1.253 | 0.9427 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.064 | 1.530 | 1.456 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 24</span>| 762.76203 | 1.002 | -0.9355 | -1.391 | -0.2569 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9025 | -0.9170 | -0.3107 | -0.4228 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1716 | -0.9179 | -0.7317 | -1.064 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6028 | -0.7161 | -0.7829 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.76203 | 97.18 | -2.890 | -4.228 | -4.957 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.978 | 2.664 | 0.8706 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7578 | 0.8028 | 1.260 | 0.9450 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.068 | 1.549 | 1.459 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.76203</span> | 97.18 | 0.05557 | 0.01459 | 0.007034 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1148 | 0.1215 | 2.664 | 0.8706 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7578 | 0.8028 | 1.260 | 0.9450 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.068 | 1.549 | 1.459 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 54.31 | -0.1887 | 0.3021 | -0.9307 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2254 | 0.1583 | -1.328 | -0.4242 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.868 | -1.362 | -1.371 | -0.08091 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.408 | -3.948 | -0.5076 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 25</span>| 762.67102 | 0.9998 | -0.9349 | -1.387 | -0.2432 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9003 | -0.9168 | -0.3029 | -0.4253 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1712 | -0.9066 | -0.7353 | -1.085 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5940 | -0.7040 | -0.7794 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.67102 | 96.98 | -2.889 | -4.224 | -4.943 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.038 | -1.978 | 2.672 | 0.8697 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7579 | 0.8123 | 1.256 | 0.9195 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.075 | 1.566 | 1.464 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.67102</span> | 96.98 | 0.05561 | 0.01464 | 0.007132 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1153 | 0.1216 | 2.672 | 0.8697 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7579 | 0.8123 | 1.256 | 0.9195 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.075 | 1.566 | 1.464 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.974 | -0.1351 | 0.3572 | -0.8415 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6736 | -0.1073 | -0.7732 | -0.4654 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.903 | -1.199 | -1.653 | -3.516 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.220 | -3.098 | -0.3193 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 26</span>| 762.64017 | 0.9999 | -0.9344 | -1.376 | -0.2262 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9040 | -0.9165 | -0.3113 | -0.4148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1768 | -0.8962 | -0.7385 | -1.074 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5804 | -0.6983 | -0.7733 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.64017 | 96.99 | -2.889 | -4.213 | -4.926 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.046 | -1.977 | 2.664 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7564 | 0.8211 | 1.252 | 0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.087 | 1.573 | 1.472 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.64017</span> | 96.99 | 0.05564 | 0.01480 | 0.007254 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1145 | 0.1216 | 2.664 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7564 | 0.8211 | 1.252 | 0.9329 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.087 | 1.573 | 1.472 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.599 | -0.1184 | 0.4302 | -0.7157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5570 | -0.2072 | -1.823 | 0.1166 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -3.571 | -0.7852 | -1.969 | -1.423 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5877 | -2.399 | -0.03479 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 27</span>| 763.13274 | 1.006 | -0.9334 | -1.371 | -0.2107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9029 | -0.9149 | -0.3061 | -0.4144 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1571 | -0.8894 | -0.7216 | -1.068 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5763 | -0.6939 | -0.7717 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 763.13274 | 97.59 | -2.888 | -4.208 | -4.911 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.043 | -1.974 | 2.669 | 0.8736 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7619 | 0.8268 | 1.271 | 0.9397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.090 | 1.579 | 1.474 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 763.13274</span> | 97.59 | 0.05569 | 0.01488 | 0.007367 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1147 | 0.1220 | 2.669 | 0.8736 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7619 | 0.8268 | 1.271 | 0.9397 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.090 | 1.579 | 1.474 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 28</span>| 762.63967 | 1.001 | -0.9343 | -1.377 | -0.2257 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9036 | -0.9164 | -0.3100 | -0.4149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1742 | -0.8956 | -0.7371 | -1.073 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5800 | -0.6966 | -0.7733 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.63967 | 97.10 | -2.889 | -4.214 | -4.926 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.045 | -1.977 | 2.665 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7571 | 0.8216 | 1.254 | 0.9341 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.087 | 1.576 | 1.472 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.63967</span> | 97.10 | 0.05564 | 0.01479 | 0.007258 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1146 | 0.1217 | 2.665 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7571 | 0.8216 | 1.254 | 0.9341 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.087 | 1.576 | 1.472 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 34.39 | -0.1342 | 0.4309 | -0.7057 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3094 | -0.07498 | -1.436 | 0.2859 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -3.195 | -0.5698 | -1.754 | -1.179 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7834 | -2.640 | -0.03401 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 29</span>| 762.61838 | 0.9999 | -0.9342 | -1.376 | -0.2247 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9037 | -0.9164 | -0.3101 | -0.4150 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1736 | -0.8955 | -0.7362 | -1.073 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5799 | -0.6970 | -0.7733 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.61838 | 96.99 | -2.889 | -4.213 | -4.925 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.045 | -1.977 | 2.665 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7573 | 0.8216 | 1.255 | 0.9344 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.087 | 1.575 | 1.472 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.61838</span> | 96.99 | 0.05564 | 0.01480 | 0.007265 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1146 | 0.1217 | 2.665 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7573 | 0.8216 | 1.255 | 0.9344 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.087 | 1.575 | 1.472 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.755 | -0.1162 | 0.4295 | -0.7030 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4902 | -0.1819 | -1.508 | 0.3366 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -3.097 | -0.6862 | -1.700 | -1.138 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.9036 | -2.963 | -0.05834 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 30</span>| 762.61305 | 1.000 | -0.9342 | -1.376 | -0.2240 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9037 | -0.9164 | -0.3097 | -0.4155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1725 | -0.8955 | -0.7354 | -1.072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5794 | -0.6961 | -0.7733 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.61305 | 97.04 | -2.889 | -4.213 | -4.924 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.045 | -1.977 | 2.665 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7576 | 0.8217 | 1.256 | 0.9348 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.087 | 1.576 | 1.472 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.61305</span> | 97.04 | 0.05565 | 0.01480 | 0.007270 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1146 | 0.1217 | 2.665 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7576 | 0.8217 | 1.256 | 0.9348 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.087 | 1.576 | 1.472 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 14.76 | -0.1238 | 0.4322 | -0.6935 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4217 | -0.1389 | -1.290 | 0.3261 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -3.236 | -0.7060 | -1.644 | -1.160 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7164 | -2.626 | -0.06595 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 31</span>| 762.60623 | 0.9999 | -0.9342 | -1.376 | -0.2227 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9039 | -0.9165 | -0.3102 | -0.4162 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1716 | -0.8955 | -0.7347 | -1.072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5791 | -0.6961 | -0.7733 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.60623 | 96.99 | -2.889 | -4.213 | -4.923 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.045 | -1.977 | 2.665 | 0.8729 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7578 | 0.8216 | 1.257 | 0.9348 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.088 | 1.576 | 1.472 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.60623</span> | 96.99 | 0.05565 | 0.01481 | 0.007279 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1145 | 0.1216 | 2.665 | 0.8729 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7578 | 0.8216 | 1.257 | 0.9348 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.088 | 1.576 | 1.472 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.846 | -0.1151 | 0.4344 | -0.6824 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5544 | -0.2171 | -1.375 | 0.3027 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.857 | -0.6587 | -1.590 | -1.961 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8624 | -2.600 | -0.06827 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 32</span>| 762.60133 | 1.000 | -0.9341 | -1.375 | -0.2218 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9039 | -0.9164 | -0.3101 | -0.4167 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1705 | -0.8954 | -0.7339 | -1.072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5787 | -0.6957 | -0.7733 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.60133 | 97.04 | -2.889 | -4.212 | -4.922 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.045 | -1.977 | 2.665 | 0.8727 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7581 | 0.8217 | 1.258 | 0.9357 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.088 | 1.577 | 1.472 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.60133</span> | 97.04 | 0.05565 | 0.01481 | 0.007286 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1145 | 0.1216 | 2.665 | 0.8727 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7581 | 0.8217 | 1.258 | 0.9357 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.088 | 1.577 | 1.472 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 13.48 | -0.1210 | 0.4371 | -0.6694 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4912 | -0.1711 | -1.470 | 0.1448 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.873 | -0.6387 | -1.543 | -1.867 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7020 | -2.876 | -0.07344 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 33</span>| 762.59465 | 0.9999 | -0.9341 | -1.375 | -0.2207 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9040 | -0.9164 | -0.3095 | -0.4173 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1704 | -0.8960 | -0.7329 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5790 | -0.6956 | -0.7733 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.59465 | 96.99 | -2.889 | -4.212 | -4.921 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.046 | -1.977 | 2.666 | 0.8726 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7582 | 0.8213 | 1.259 | 0.9366 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.088 | 1.577 | 1.472 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.59465</span> | 96.99 | 0.05565 | 0.01482 | 0.007294 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1145 | 0.1216 | 2.666 | 0.8726 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7582 | 0.8213 | 1.259 | 0.9366 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.088 | 1.577 | 1.472 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.775 | -0.1124 | 0.4366 | -0.6552 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5921 | -0.2206 | -1.396 | 0.1541 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.894 | -0.7001 | -1.461 | -0.9904 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8842 | -2.566 | -0.07283 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 34</span>| 762.59066 | 1.000 | -0.9340 | -1.375 | -0.2198 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9038 | -0.9163 | -0.3089 | -0.4174 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1692 | -0.8959 | -0.7322 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5787 | -0.6947 | -0.7733 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.59066 | 97.04 | -2.889 | -4.212 | -4.920 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.045 | -1.977 | 2.666 | 0.8725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7585 | 0.8213 | 1.259 | 0.9371 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.088 | 1.578 | 1.472 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.59066</span> | 97.04 | 0.05566 | 0.01482 | 0.007300 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1145 | 0.1217 | 2.666 | 0.8725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7585 | 0.8213 | 1.259 | 0.9371 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.088 | 1.578 | 1.472 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 16.18 | -0.1194 | 0.4391 | -0.6416 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4865 | -0.1542 | -1.319 | 0.1335 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.691 | -0.6283 | -1.400 | -0.9220 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7113 | -2.508 | -0.07019 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 35</span>| 762.58429 | 0.9999 | -0.9339 | -1.375 | -0.2184 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9040 | -0.9163 | -0.3092 | -0.4175 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1684 | -0.8956 | -0.7319 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5779 | -0.6949 | -0.7734 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.58429 | 96.99 | -2.888 | -4.212 | -4.918 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.046 | -1.977 | 2.666 | 0.8725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7587 | 0.8216 | 1.260 | 0.9368 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.089 | 1.578 | 1.472 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.58429</span> | 96.99 | 0.05566 | 0.01482 | 0.007311 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1145 | 0.1217 | 2.666 | 0.8725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7587 | 0.8216 | 1.260 | 0.9368 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.089 | 1.578 | 1.472 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.054 | -0.1077 | 0.4392 | -0.6327 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5920 | -0.2170 | -1.368 | 0.1202 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.662 | -0.6439 | -1.388 | -1.754 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8733 | -2.532 | -0.1003 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 36</span>| 762.57982 | 1.000 | -0.9338 | -1.375 | -0.2170 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9039 | -0.9162 | -0.3086 | -0.4176 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1676 | -0.8956 | -0.7312 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5773 | -0.6947 | -0.7733 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.57982 | 97.02 | -2.888 | -4.212 | -4.917 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.046 | -1.977 | 2.666 | 0.8724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7589 | 0.8216 | 1.261 | 0.9374 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.089 | 1.578 | 1.472 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.57982</span> | 97.02 | 0.05567 | 0.01482 | 0.007321 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1145 | 0.1217 | 2.666 | 0.8724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7589 | 0.8216 | 1.261 | 0.9374 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.089 | 1.578 | 1.472 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 9.173 | -0.1105 | 0.4413 | -0.6162 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5474 | -0.1732 | -1.159 | 0.1830 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.846 | -0.7034 | -1.343 | -0.9047 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6908 | -2.510 | -0.09661 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 37</span>| 762.57572 | 0.9999 | -0.9337 | -1.375 | -0.2157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9040 | -0.9162 | -0.3092 | -0.4178 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1663 | -0.8953 | -0.7312 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5771 | -0.6947 | -0.7731 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.57572 | 96.99 | -2.888 | -4.212 | -4.916 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.046 | -1.977 | 2.666 | 0.8724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7593 | 0.8218 | 1.261 | 0.9374 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.089 | 1.578 | 1.472 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.57572</span> | 96.99 | 0.05567 | 0.01482 | 0.007331 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1145 | 0.1217 | 2.666 | 0.8724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7593 | 0.8218 | 1.261 | 0.9374 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.089 | 1.578 | 1.472 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.338 | -0.1030 | 0.4402 | -0.6028 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6140 | -0.2137 | -1.433 | 0.08084 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.656 | -0.6680 | -1.346 | -1.715 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8965 | -2.853 | -0.1247 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 38</span>| 762.57150 | 1.000 | -0.9337 | -1.375 | -0.2145 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9040 | -0.9162 | -0.3094 | -0.4180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1650 | -0.8953 | -0.7314 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5771 | -0.6938 | -0.7730 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.5715 | 97.02 | -2.888 | -4.212 | -4.915 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.046 | -1.977 | 2.666 | 0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7597 | 0.8218 | 1.260 | 0.9374 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.089 | 1.579 | 1.472 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.5715</span> | 97.02 | 0.05568 | 0.01482 | 0.007339 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1145 | 0.1217 | 2.666 | 0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7597 | 0.8218 | 1.260 | 0.9374 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.089 | 1.579 | 1.472 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 9.917 | -0.1081 | 0.4404 | -0.5845 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5548 | -0.1795 | -1.372 | 0.08332 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.404 | -0.6107 | -1.343 | -1.668 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7053 | -2.471 | -0.08527 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 39</span>| 762.56652 | 0.9998 | -0.9337 | -1.375 | -0.2137 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9039 | -0.9161 | -0.3083 | -0.4179 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1654 | -0.8958 | -0.7313 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5775 | -0.6927 | -0.7729 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.56652 | 96.98 | -2.888 | -4.212 | -4.914 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.045 | -1.976 | 2.667 | 0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7596 | 0.8214 | 1.260 | 0.9380 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.089 | 1.581 | 1.472 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.56652</span> | 96.98 | 0.05568 | 0.01482 | 0.007345 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1145 | 0.1217 | 2.667 | 0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7596 | 0.8214 | 1.260 | 0.9380 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.089 | 1.581 | 1.472 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.202 | -0.09986 | 0.4343 | -0.5734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5963 | -0.2059 | -1.230 | 0.1366 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.439 | -0.6793 | -1.344 | -1.610 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8864 | -2.392 | -0.08042 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 40</span>| 762.56246 | 1.000 | -0.9336 | -1.375 | -0.2125 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9039 | -0.9160 | -0.3073 | -0.4180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1656 | -0.8955 | -0.7303 | -1.069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5773 | -0.6925 | -0.7730 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.56246 | 97.01 | -2.888 | -4.212 | -4.913 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.045 | -1.976 | 2.668 | 0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7595 | 0.8216 | 1.262 | 0.9386 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.089 | 1.581 | 1.472 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.56246</span> | 97.01 | 0.05568 | 0.01481 | 0.007354 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1145 | 0.1217 | 2.668 | 0.8723 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7595 | 0.8216 | 1.262 | 0.9386 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.089 | 1.581 | 1.472 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.335 | -0.1021 | 0.4320 | -0.5553 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5609 | -0.1614 | -1.231 | 0.02142 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.620 | -0.6772 | -1.305 | -1.580 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7609 | -2.720 | -0.1132 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 41</span>| 762.55730 | 0.9999 | -0.9335 | -1.376 | -0.2115 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9037 | -0.9159 | -0.3071 | -0.4174 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1649 | -0.8958 | -0.7301 | -1.069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5781 | -0.6915 | -0.7731 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.5573 | 96.99 | -2.888 | -4.213 | -4.912 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.045 | -1.976 | 2.668 | 0.8725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7597 | 0.8214 | 1.262 | 0.9390 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.089 | 1.583 | 1.472 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.5573</span> | 96.99 | 0.05568 | 0.01481 | 0.007361 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1146 | 0.1218 | 2.668 | 0.8725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7597 | 0.8214 | 1.262 | 0.9390 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.089 | 1.583 | 1.472 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 42</span>| 762.55308 | 1.000 | -0.9335 | -1.376 | -0.2104 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9036 | -0.9158 | -0.3069 | -0.4167 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1644 | -0.8961 | -0.7300 | -1.068 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5790 | -0.6904 | -0.7733 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.55308 | 97.00 | -2.888 | -4.213 | -4.910 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.045 | -1.976 | 2.668 | 0.8727 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7598 | 0.8211 | 1.262 | 0.9393 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.088 | 1.584 | 1.472 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.55308</span> | 97.00 | 0.05568 | 0.01480 | 0.007369 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1146 | 0.1218 | 2.668 | 0.8727 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7598 | 0.8211 | 1.262 | 0.9393 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.088 | 1.584 | 1.472 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 43</span>| 762.54129 | 1.000 | -0.9334 | -1.378 | -0.2065 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9033 | -0.9153 | -0.3062 | -0.4144 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1625 | -0.8972 | -0.7297 | -1.067 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5824 | -0.6868 | -0.7739 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.54129 | 97.02 | -2.888 | -4.215 | -4.907 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.044 | -1.975 | 2.669 | 0.8736 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7604 | 0.8202 | 1.262 | 0.9405 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.085 | 1.589 | 1.471 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.54129</span> | 97.02 | 0.05569 | 0.01477 | 0.007398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1147 | 0.1219 | 2.669 | 0.8736 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7604 | 0.8202 | 1.262 | 0.9405 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.085 | 1.589 | 1.471 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 44</span>| 762.53205 | 1.001 | -0.9333 | -1.381 | -0.1995 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9026 | -0.9144 | -0.3049 | -0.4101 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1590 | -0.8993 | -0.7291 | -1.066 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5885 | -0.6801 | -0.7749 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.53205 | 97.07 | -2.888 | -4.218 | -4.899 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.043 | -1.973 | 2.670 | 0.8751 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7613 | 0.8185 | 1.263 | 0.9425 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.080 | 1.598 | 1.470 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.53205</span> | 97.07 | 0.05570 | 0.01472 | 0.007451 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1148 | 0.1221 | 2.670 | 0.8751 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7613 | 0.8185 | 1.263 | 0.9425 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.080 | 1.598 | 1.470 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 23.65 | -0.1039 | 0.3653 | -0.2919 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1880 | 0.2896 | -0.9107 | 0.7013 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.202 | -0.8082 | -1.198 | -1.067 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.416 | -1.756 | -0.2090 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 45</span>| 762.48327 | 0.9998 | -0.9329 | -1.391 | -0.1822 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9041 | -0.9140 | -0.3019 | -0.4150 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1512 | -0.8995 | -0.7234 | -1.064 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5784 | -0.6773 | -0.7751 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.48327 | 96.98 | -2.887 | -4.228 | -4.882 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.046 | -1.972 | 2.674 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7635 | 0.8183 | 1.269 | 0.9450 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.088 | 1.602 | 1.470 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.48327</span> | 96.98 | 0.05572 | 0.01458 | 0.007580 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1145 | 0.1222 | 2.674 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7635 | 0.8183 | 1.269 | 0.9450 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.088 | 1.602 | 1.470 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.920 | -0.08029 | 0.2756 | -0.1231 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7850 | 0.1611 | -0.6966 | 0.2967 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.718 | -0.8812 | -0.8270 | -0.2301 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.116 | -1.224 | -0.3843 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 46</span>| 762.47327 | 1.000 | -0.9318 | -1.401 | -0.1764 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9027 | -0.9109 | -0.3019 | -0.4099 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1415 | -0.8907 | -0.7247 | -1.067 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5685 | -0.6781 | -0.7620 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.47327 | 97.01 | -2.886 | -4.238 | -4.876 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.043 | -1.966 | 2.673 | 0.8752 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7662 | 0.8257 | 1.268 | 0.9409 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.097 | 1.601 | 1.487 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.47327</span> | 97.01 | 0.05578 | 0.01443 | 0.007624 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1148 | 0.1228 | 2.673 | 0.8752 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7662 | 0.8257 | 1.268 | 0.9409 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.097 | 1.601 | 1.487 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.304 | -0.04991 | 0.1861 | -0.1521 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2758 | 0.6987 | -0.6385 | 0.6999 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.104 | -0.4937 | -0.9023 | -1.218 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -1.007 | -1.649 | 0.3798 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 47</span>| 762.45236 | 1.000 | -0.9314 | -1.416 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9025 | -0.9126 | -0.3007 | -0.4145 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1407 | -0.8864 | -0.7274 | -1.072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5562 | -0.6663 | -0.7693 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.45236 | 97.00 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.969 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7665 | 0.8293 | 1.265 | 0.9352 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.617 | 1.477 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.45236</span> | 97.00 | 0.05580 | 0.01423 | 0.007643 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1148 | 0.1225 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7665 | 0.8293 | 1.265 | 0.9352 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.617 | 1.477 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.090 | -0.03836 | 0.07211 | -0.1660 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2360 | 0.2575 | -0.5787 | 0.3648 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.053 | -0.3652 | -1.069 | -1.349 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4799 | -1.042 | -0.1902 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 48</span>| 762.47705 | 0.9990 | -0.9326 | -1.425 | -0.1717 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9039 | -0.9116 | -0.2960 | -0.4278 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1499 | -0.8783 | -0.6879 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5536 | -0.6497 | -0.7536 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.47705 | 96.90 | -2.887 | -4.262 | -4.872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.045 | -1.967 | 2.680 | 0.8688 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7639 | 0.8361 | 1.309 | 0.9365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.639 | 1.499 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.47705</span> | 96.90 | 0.05574 | 0.01410 | 0.007660 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1145 | 0.1227 | 2.680 | 0.8688 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7639 | 0.8361 | 1.309 | 0.9365 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.639 | 1.499 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 49</span>| 762.47045 | 0.9985 | -0.9319 | -1.419 | -0.1731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9029 | -0.9123 | -0.2988 | -0.4194 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1437 | -0.8834 | -0.7128 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5551 | -0.6600 | -0.7636 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.47045 | 96.85 | -2.886 | -4.256 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.043 | -1.969 | 2.677 | 0.8718 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7656 | 0.8318 | 1.281 | 0.9361 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.625 | 1.485 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.47045</span> | 96.85 | 0.05578 | 0.01418 | 0.007650 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1147 | 0.1225 | 2.677 | 0.8718 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7656 | 0.8318 | 1.281 | 0.9361 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.625 | 1.485 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 50</span>| 762.49004 | 0.9982 | -0.9315 | -1.417 | -0.1736 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9025 | -0.9126 | -0.3000 | -0.4160 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1412 | -0.8855 | -0.7230 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5558 | -0.6642 | -0.7677 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.49004 | 96.83 | -2.886 | -4.254 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.043 | -1.969 | 2.675 | 0.8730 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7663 | 0.8301 | 1.270 | 0.9360 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.619 | 1.480 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.49004</span> | 96.83 | 0.05579 | 0.01421 | 0.007645 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1148 | 0.1225 | 2.675 | 0.8730 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7663 | 0.8301 | 1.270 | 0.9360 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.619 | 1.480 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 51</span>| 762.45852 | 0.9993 | -0.9314 | -1.416 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9024 | -0.9127 | -0.3006 | -0.4146 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1405 | -0.8864 | -0.7272 | -1.072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5561 | -0.6661 | -0.7693 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.45852 | 96.93 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.969 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7665 | 0.8293 | 1.265 | 0.9355 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.617 | 1.477 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.45852</span> | 96.93 | 0.05580 | 0.01423 | 0.007643 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1148 | 0.1224 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7665 | 0.8293 | 1.265 | 0.9355 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.617 | 1.477 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 52</span>| 762.45201 | 0.9999 | -0.9314 | -1.416 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9025 | -0.9126 | -0.3007 | -0.4145 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1407 | -0.8864 | -0.7274 | -1.072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5562 | -0.6663 | -0.7693 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.45201 | 96.99 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.969 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7665 | 0.8293 | 1.265 | 0.9352 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.617 | 1.477 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.45201</span> | 96.99 | 0.05580 | 0.01423 | 0.007643 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1148 | 0.1225 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7665 | 0.8293 | 1.265 | 0.9352 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.617 | 1.477 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.157 | -0.03565 | 0.07096 | -0.1676 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2565 | 0.2382 | -0.5340 | 0.4141 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.202 | -0.3942 | -1.048 | -1.363 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4633 | -1.025 | -0.1715 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 53</span>| 762.45163 | 1.000 | -0.9314 | -1.416 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9025 | -0.9127 | -0.3007 | -0.4145 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1406 | -0.8864 | -0.7273 | -1.072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5562 | -0.6662 | -0.7693 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.45163 | 97.00 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.969 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7665 | 0.8293 | 1.265 | 0.9353 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.617 | 1.477 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.45163</span> | 97.00 | 0.05580 | 0.01423 | 0.007643 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1148 | 0.1225 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7665 | 0.8293 | 1.265 | 0.9353 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.617 | 1.477 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.387 | -0.03697 | 0.07095 | -0.1670 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2405 | 0.2417 | -0.4946 | 0.4249 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9410 | -0.3603 | -1.076 | -0.6985 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5549 | -0.6934 | -0.1964 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 54</span>| 762.45142 | 0.9999 | -0.9314 | -1.416 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9024 | -0.9127 | -0.3006 | -0.4146 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1405 | -0.8864 | -0.7272 | -1.072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5561 | -0.6662 | -0.7693 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.45142 | 96.99 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.969 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7665 | 0.8293 | 1.265 | 0.9354 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.617 | 1.477 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.45142</span> | 96.99 | 0.05580 | 0.01423 | 0.007643 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1148 | 0.1224 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7665 | 0.8293 | 1.265 | 0.9354 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.617 | 1.477 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.093 | -0.03511 | 0.07006 | -0.1682 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2501 | 0.2258 | -0.7319 | 0.2456 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.092 | -0.3868 | -1.095 | -0.7218 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5798 | -0.7078 | -0.2098 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 55</span>| 762.45106 | 1.000 | -0.9314 | -1.416 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9024 | -0.9127 | -0.3006 | -0.4146 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1405 | -0.8863 | -0.7271 | -1.072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5561 | -0.6661 | -0.7693 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.45106 | 97.00 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.969 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7665 | 0.8294 | 1.265 | 0.9355 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.617 | 1.477 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.45106</span> | 97.00 | 0.05580 | 0.01423 | 0.007644 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1148 | 0.1224 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7665 | 0.8294 | 1.265 | 0.9355 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.617 | 1.477 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.558 | -0.03666 | 0.07079 | -0.1670 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2292 | 0.2352 | -0.6822 | 0.2833 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9877 | -0.3599 | -1.086 | -0.7040 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5476 | -0.6798 | -0.1950 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 56</span>| 762.45087 | 0.9999 | -0.9314 | -1.416 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9024 | -0.9127 | -0.3005 | -0.4146 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1404 | -0.8863 | -0.7270 | -1.072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5561 | -0.6661 | -0.7693 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.45087 | 96.99 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7666 | 0.8294 | 1.265 | 0.9355 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.617 | 1.477 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.45087</span> | 96.99 | 0.05580 | 0.01423 | 0.007644 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1148 | 0.1224 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7666 | 0.8294 | 1.265 | 0.9355 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.617 | 1.477 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -2.701 | -0.06138 | 0.06188 | -0.1824 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3275 | 0.1556 | -0.5644 | 0.4107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9451 | -0.3602 | -1.050 | -0.9219 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7692 | -0.8400 | -0.2110 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 57</span>| 762.45052 | 1.000 | -0.9314 | -1.416 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9024 | -0.9127 | -0.3005 | -0.4146 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1404 | -0.8863 | -0.7269 | -1.072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5560 | -0.6660 | -0.7693 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.45052 | 97.00 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7666 | 0.8294 | 1.265 | 0.9356 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.617 | 1.477 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.45052</span> | 97.00 | 0.05580 | 0.01423 | 0.007644 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1148 | 0.1224 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7666 | 0.8294 | 1.265 | 0.9356 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.617 | 1.477 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.310 | -0.03660 | 0.07022 | -0.1677 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2216 | 0.2281 | -0.6223 | 0.3362 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.101 | -0.3801 | -1.032 | -1.332 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4655 | -1.018 | -0.1777 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 58</span>| 762.45025 | 0.9999 | -0.9314 | -1.416 | -0.1739 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9024 | -0.9127 | -0.3005 | -0.4146 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1403 | -0.8862 | -0.7268 | -1.072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5560 | -0.6659 | -0.7692 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.45025 | 96.99 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7666 | 0.8294 | 1.265 | 0.9357 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.617 | 1.477 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.45025</span> | 96.99 | 0.05580 | 0.01423 | 0.007644 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1148 | 0.1224 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7666 | 0.8294 | 1.265 | 0.9357 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.617 | 1.477 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.564 | -0.03511 | 0.06930 | -0.1687 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2301 | 0.2148 | -0.6958 | 0.2956 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.074 | -0.3641 | -1.039 | -0.6647 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5492 | -0.6891 | -0.2028 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 59</span>| 762.44994 | 1.000 | -0.9314 | -1.416 | -0.1738 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9024 | -0.9127 | -0.3004 | -0.4147 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1402 | -0.8862 | -0.7268 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5559 | -0.6659 | -0.7692 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44994 | 97.00 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7666 | 0.8295 | 1.266 | 0.9357 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.617 | 1.477 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44994</span> | 97.00 | 0.05580 | 0.01423 | 0.007644 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1148 | 0.1224 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7666 | 0.8295 | 1.266 | 0.9357 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.617 | 1.477 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.130 | -0.03693 | 0.06970 | -0.1678 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2087 | 0.2222 | -0.4767 | 0.4303 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.005 | -0.3788 | -1.043 | -1.360 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5474 | -0.6760 | -0.1925 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 60</span>| 762.44969 | 0.9999 | -0.9314 | -1.416 | -0.1738 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9024 | -0.9127 | -0.3004 | -0.4147 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1402 | -0.8862 | -0.7266 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5559 | -0.6658 | -0.7692 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44969 | 96.99 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7666 | 0.8295 | 1.266 | 0.9358 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.617 | 1.477 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44969</span> | 96.99 | 0.05580 | 0.01423 | 0.007644 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1148 | 0.1224 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7666 | 0.8295 | 1.266 | 0.9358 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.617 | 1.477 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.483 | -0.03492 | 0.06900 | -0.1687 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2211 | 0.2086 | -0.7093 | 0.2512 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9848 | -0.3396 | -1.026 | -1.317 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5572 | -0.6715 | -0.1875 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 61</span>| 762.44936 | 1.000 | -0.9314 | -1.416 | -0.1738 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9023 | -0.9128 | -0.3003 | -0.4147 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1401 | -0.8862 | -0.7266 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5558 | -0.6658 | -0.7692 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44936 | 97.00 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7666 | 0.8295 | 1.266 | 0.9359 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.617 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44936</span> | 97.00 | 0.05580 | 0.01423 | 0.007644 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1148 | 0.1224 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7666 | 0.8295 | 1.266 | 0.9359 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.617 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.828 | -0.03668 | 0.06906 | -0.1681 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2025 | 0.2148 | -0.4016 | 0.4562 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7985 | -0.3199 | -1.005 | -0.6242 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4649 | -1.017 | -0.1851 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 62</span>| 762.44920 | 0.9998 | -0.9314 | -1.416 | -0.1738 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9023 | -0.9128 | -0.3003 | -0.4147 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1401 | -0.8861 | -0.7265 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5558 | -0.6657 | -0.7692 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.4492 | 96.99 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7667 | 0.8295 | 1.266 | 0.9360 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.617 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.4492</span> | 96.99 | 0.05580 | 0.01423 | 0.007644 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7667 | 0.8295 | 1.266 | 0.9360 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.617 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -2.892 | -0.06089 | 0.06027 | -0.1834 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3033 | 0.1350 | -0.5226 | 0.3403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9268 | -0.3802 | -1.004 | -0.8849 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7517 | -0.8245 | -0.1920 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 63</span>| 762.44881 | 1.000 | -0.9314 | -1.416 | -0.1738 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9023 | -0.9128 | -0.3003 | -0.4147 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1400 | -0.8861 | -0.7264 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5558 | -0.6656 | -0.7692 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44881 | 97.00 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7667 | 0.8296 | 1.266 | 0.9360 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.617 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44881</span> | 97.00 | 0.05580 | 0.01423 | 0.007644 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.675 | 0.8735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7667 | 0.8296 | 1.266 | 0.9360 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.617 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.278 | -0.03606 | 0.06873 | -0.1684 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1982 | 0.2076 | -0.7410 | 0.2864 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9371 | -0.3600 | -0.9981 | -0.6148 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4567 | -0.9956 | -0.1730 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 64</span>| 762.44861 | 0.9999 | -0.9314 | -1.416 | -0.1738 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9023 | -0.9128 | -0.3002 | -0.4148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1400 | -0.8861 | -0.7263 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5557 | -0.6656 | -0.7691 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44861 | 96.99 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.675 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7667 | 0.8296 | 1.266 | 0.9361 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.618 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44861</span> | 96.99 | 0.05580 | 0.01423 | 0.007644 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.675 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7667 | 0.8296 | 1.266 | 0.9361 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.618 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.918 | -0.03426 | 0.06810 | -0.1693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2072 | 0.1939 | -0.5108 | 0.4012 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.125 | -0.3956 | -1.016 | -0.6465 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5398 | -0.6520 | -0.1791 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 65</span>| 762.44831 | 1.000 | -0.9314 | -1.416 | -0.1738 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9023 | -0.9128 | -0.3002 | -0.4148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1399 | -0.8861 | -0.7262 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5557 | -0.6655 | -0.7691 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44831 | 97.00 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.675 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7667 | 0.8296 | 1.266 | 0.9361 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.618 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44831</span> | 97.00 | 0.05580 | 0.01423 | 0.007645 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.675 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7667 | 0.8296 | 1.266 | 0.9361 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.618 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.263 | -0.03657 | 0.06844 | -0.1684 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1851 | 0.2030 | -0.3956 | 0.5081 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.042 | -0.3769 | -0.9733 | -0.5979 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4511 | -0.9881 | -0.1717 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 66</span>| 762.44807 | 0.9999 | -0.9314 | -1.416 | -0.1737 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9023 | -0.9128 | -0.3002 | -0.4148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1398 | -0.8860 | -0.7261 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5557 | -0.6655 | -0.7691 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44807 | 96.99 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.675 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7667 | 0.8296 | 1.266 | 0.9361 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.618 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44807</span> | 96.99 | 0.05580 | 0.01423 | 0.007645 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.675 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7667 | 0.8296 | 1.266 | 0.9361 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.618 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.676 | -0.03430 | 0.06789 | -0.1692 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2001 | 0.1879 | -0.6345 | 0.2243 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9985 | -0.3646 | -0.9895 | -0.6233 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5267 | -0.6582 | -0.1873 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 67</span>| 762.44780 | 1.000 | -0.9314 | -1.416 | -0.1737 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9023 | -0.9128 | -0.3001 | -0.4149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1398 | -0.8860 | -0.7261 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5556 | -0.6654 | -0.7691 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.4478 | 97.00 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.675 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7667 | 0.8297 | 1.266 | 0.9362 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.618 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.4478</span> | 97.00 | 0.05580 | 0.01423 | 0.007645 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.675 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7667 | 0.8297 | 1.266 | 0.9362 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.618 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.318 | -0.03631 | 0.06808 | -0.1685 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1789 | 0.1959 | -0.7173 | 0.2475 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9453 | -0.3416 | -0.9621 | -0.5903 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4826 | -0.9880 | -0.1748 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 68</span>| 762.44757 | 0.9999 | -0.9314 | -1.416 | -0.1737 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9023 | -0.9128 | -0.3001 | -0.4149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1397 | -0.8860 | -0.7260 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5556 | -0.6653 | -0.7691 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44757 | 96.99 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.675 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7667 | 0.8297 | 1.266 | 0.9362 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.107 | 1.618 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44757</span> | 96.99 | 0.05580 | 0.01423 | 0.007645 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.675 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7667 | 0.8297 | 1.266 | 0.9362 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.107 | 1.618 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.403 | -0.03410 | 0.06766 | -0.1693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1923 | 0.1827 | -0.5754 | 0.3333 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.026 | -0.3445 | -0.9634 | -0.5940 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4852 | -0.9871 | -0.1745 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 69</span>| 762.44726 | 1.000 | -0.9314 | -1.416 | -0.1737 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9022 | -0.9129 | -0.3000 | -0.4149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1396 | -0.8859 | -0.7259 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5555 | -0.6653 | -0.7691 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44726 | 97.00 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.675 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7668 | 0.8297 | 1.266 | 0.9363 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.618 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44726</span> | 97.00 | 0.05580 | 0.01423 | 0.007645 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.675 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7668 | 0.8297 | 1.266 | 0.9363 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.618 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.060 | -0.03580 | 0.06800 | -0.1685 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1728 | 0.1899 | -0.4704 | 0.4284 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9227 | -0.3505 | -0.9813 | -0.6228 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5193 | -0.6388 | -0.1848 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 70</span>| 762.44712 | 0.9998 | -0.9314 | -1.416 | -0.1737 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9022 | -0.9129 | -0.3000 | -0.4149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1396 | -0.8859 | -0.7258 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5555 | -0.6652 | -0.7691 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44712 | 96.99 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7668 | 0.8297 | 1.267 | 0.9363 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.618 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44712</span> | 96.99 | 0.05580 | 0.01423 | 0.007645 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7668 | 0.8297 | 1.267 | 0.9363 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.618 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -2.853 | -0.06042 | 0.05902 | -0.1840 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2766 | 0.1092 | -0.5247 | 0.3320 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8590 | -0.3265 | -0.9669 | -0.8543 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7362 | -0.6424 | -0.1982 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 71</span>| 762.44677 | 1.000 | -0.9314 | -1.416 | -0.1736 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9022 | -0.9129 | -0.3000 | -0.4149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1396 | -0.8859 | -0.7257 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5555 | -0.6652 | -0.7690 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44677 | 97.00 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7668 | 0.8297 | 1.267 | 0.9363 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.618 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44677</span> | 97.00 | 0.05580 | 0.01423 | 0.007645 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7668 | 0.8297 | 1.267 | 0.9363 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.618 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.229 | -0.03534 | 0.06769 | -0.1687 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1722 | 0.1825 | -0.6577 | 0.2295 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9683 | -0.3540 | -0.9833 | -0.6305 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5492 | -0.6462 | -0.1881 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 72</span>| 762.44660 | 0.9999 | -0.9314 | -1.416 | -0.1736 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9022 | -0.9129 | -0.2999 | -0.4149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1395 | -0.8858 | -0.7256 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5554 | -0.6651 | -0.7690 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.4466 | 96.99 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7668 | 0.8298 | 1.267 | 0.9364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.618 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.4466</span> | 96.99 | 0.05580 | 0.01423 | 0.007646 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7668 | 0.8298 | 1.267 | 0.9364 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.618 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -2.619 | -0.06037 | 0.05887 | -0.1840 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2697 | 0.1047 | -0.4880 | 0.3107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8777 | -0.3347 | -0.9510 | -0.8415 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8070 | -0.6380 | -0.2003 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 73</span>| 762.44631 | 1.000 | -0.9314 | -1.416 | -0.1736 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9022 | -0.9129 | -0.2999 | -0.4149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1395 | -0.8858 | -0.7255 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5554 | -0.6651 | -0.7690 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44631 | 97.00 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7668 | 0.8298 | 1.267 | 0.9364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.618 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44631</span> | 97.00 | 0.05580 | 0.01423 | 0.007646 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7668 | 0.8298 | 1.267 | 0.9364 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.618 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.239 | -0.03523 | 0.06754 | -0.1690 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1652 | 0.1779 | -0.5810 | 0.3500 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9310 | -0.3299 | -0.9168 | -0.5544 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4590 | -0.9780 | -0.1676 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 74</span>| 762.44612 | 0.9999 | -0.9314 | -1.416 | -0.1736 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9022 | -0.9129 | -0.2998 | -0.4150 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1394 | -0.8858 | -0.7254 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5553 | -0.6650 | -0.7690 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44612 | 96.99 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7668 | 0.8298 | 1.267 | 0.9365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.618 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44612</span> | 96.99 | 0.05580 | 0.01423 | 0.007646 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7668 | 0.8298 | 1.267 | 0.9365 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.618 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -2.595 | -0.06025 | 0.05873 | -0.1842 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2631 | 0.1003 | -0.4975 | 0.3199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8775 | -0.3517 | -0.9324 | -0.8365 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7469 | -0.7872 | -0.1921 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 75</span>| 762.44579 | 1.000 | -0.9314 | -1.416 | -0.1736 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9022 | -0.9129 | -0.2998 | -0.4150 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1394 | -0.8858 | -0.7253 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5553 | -0.6649 | -0.7690 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44579 | 97.00 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7668 | 0.8298 | 1.267 | 0.9365 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.618 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44579</span> | 97.00 | 0.05580 | 0.01423 | 0.007646 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7668 | 0.8298 | 1.267 | 0.9365 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.618 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.332 | -0.03503 | 0.06745 | -0.1690 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1595 | 0.1733 | -0.6521 | 0.2265 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.099 | -0.3762 | -1.004 | -0.8055 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5808 | -0.6379 | -0.1715 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 76</span>| 762.44562 | 0.9999 | -0.9314 | -1.416 | -0.1736 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9022 | -0.9129 | -0.2997 | -0.4150 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1393 | -0.8857 | -0.7252 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5552 | -0.6649 | -0.7690 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44562 | 96.99 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7669 | 0.8299 | 1.267 | 0.9366 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.618 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44562</span> | 96.99 | 0.05580 | 0.01423 | 0.007646 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7669 | 0.8299 | 1.267 | 0.9366 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.618 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -2.540 | -0.06014 | 0.05853 | -0.1843 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2582 | 0.09555 | -0.4805 | 0.3174 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8832 | -0.3610 | -0.9182 | -0.8220 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7344 | -0.7852 | -0.1863 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 77</span>| 762.44533 | 1.000 | -0.9314 | -1.416 | -0.1735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9022 | -0.9129 | -0.2997 | -0.4150 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1393 | -0.8857 | -0.7251 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5552 | -0.6648 | -0.7690 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44533 | 97.00 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7669 | 0.8299 | 1.267 | 0.9366 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.619 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44533</span> | 97.00 | 0.05580 | 0.01423 | 0.007646 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7669 | 0.8299 | 1.267 | 0.9366 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.619 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.707 | -0.03519 | 0.06722 | -0.1691 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1517 | 0.1695 | -0.2998 | 0.5346 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9157 | -0.3444 | -0.9296 | -0.7244 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4238 | -0.9503 | -0.1555 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 78</span>| 762.44512 | 0.9999 | -0.9314 | -1.416 | -0.1735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9022 | -0.9129 | -0.2997 | -0.4151 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1392 | -0.8857 | -0.7250 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5551 | -0.6647 | -0.7690 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44512 | 96.99 | -2.886 | -4.253 | -4.874 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7669 | 0.8299 | 1.267 | 0.9367 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.619 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44512</span> | 96.99 | 0.05580 | 0.01423 | 0.007646 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7669 | 0.8299 | 1.267 | 0.9367 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.619 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.725 | -0.03313 | 0.06674 | -0.1698 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1647 | 0.1564 | -0.4671 | 0.3596 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.122 | -0.3749 | -0.8900 | -0.5488 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4408 | -0.9435 | -0.1591 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 79</span>| 762.44482 | 1.000 | -0.9314 | -1.416 | -0.1735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9021 | -0.9129 | -0.2997 | -0.4151 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1391 | -0.8856 | -0.7249 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5551 | -0.6647 | -0.7689 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44482 | 97.00 | -2.886 | -4.253 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7669 | 0.8299 | 1.268 | 0.9367 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.619 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44482</span> | 97.00 | 0.05580 | 0.01423 | 0.007647 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7669 | 0.8299 | 1.268 | 0.9367 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.619 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.165 | -0.03526 | 0.06705 | -0.1689 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1452 | 0.1649 | -0.6916 | 0.2043 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.053 | -0.3782 | -0.9414 | -1.376 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4339 | -0.9640 | -0.1678 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 80</span>| 762.44457 | 0.9999 | -0.9314 | -1.416 | -0.1735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9021 | -0.9129 | -0.2997 | -0.4151 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1391 | -0.8856 | -0.7248 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5551 | -0.6646 | -0.7689 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44457 | 96.99 | -2.886 | -4.253 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7669 | 0.8300 | 1.268 | 0.9368 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.619 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44457</span> | 96.99 | 0.05580 | 0.01423 | 0.007647 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7669 | 0.8300 | 1.268 | 0.9368 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.619 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.241 | -0.03355 | 0.06646 | -0.1694 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1600 | 0.1522 | -0.4229 | 0.3779 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8707 | -0.3333 | -0.8636 | -0.5164 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4114 | -0.9432 | -0.1630 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 81</span>| 762.44429 | 1.000 | -0.9314 | -1.416 | -0.1734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9021 | -0.9130 | -0.2996 | -0.4151 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1390 | -0.8856 | -0.7247 | -1.071 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5551 | -0.6645 | -0.7689 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44429 | 97.00 | -2.886 | -4.253 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7669 | 0.8300 | 1.268 | 0.9368 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.619 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44429</span> | 97.00 | 0.05580 | 0.01423 | 0.007647 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7669 | 0.8300 | 1.268 | 0.9368 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.619 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.194 | -0.03535 | 0.06668 | -0.1687 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1413 | 0.1590 | -0.5714 | 0.3381 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9309 | -0.3230 | -0.9277 | -0.7053 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4161 | -0.9324 | -0.1528 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 82</span>| 762.44403 | 0.9999 | -0.9314 | -1.416 | -0.1734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9021 | -0.9130 | -0.2996 | -0.4152 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1390 | -0.8855 | -0.7246 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5550 | -0.6645 | -0.7689 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44403 | 96.99 | -2.886 | -4.253 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8300 | 1.268 | 0.9369 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.619 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44403</span> | 96.99 | 0.05580 | 0.01423 | 0.007647 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8300 | 1.268 | 0.9369 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.619 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.197 | -0.03347 | 0.06628 | -0.1692 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1562 | 0.1463 | -0.5532 | 0.2989 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9647 | -0.3192 | -0.9128 | -0.7175 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4587 | -0.9463 | -0.1607 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 83</span>| 762.44374 | 1.000 | -0.9314 | -1.416 | -0.1734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9021 | -0.9130 | -0.2996 | -0.4152 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1389 | -0.8855 | -0.7245 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5550 | -0.6644 | -0.7689 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44374 | 97.00 | -2.886 | -4.253 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8301 | 1.268 | 0.9369 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.619 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44374</span> | 97.00 | 0.05580 | 0.01423 | 0.007647 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8301 | 1.268 | 0.9369 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.619 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.963 | -0.03502 | 0.06649 | -0.1685 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1388 | 0.1528 | -0.5508 | 0.3111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7878 | -0.3058 | -0.9061 | -0.7073 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4580 | -0.9428 | -0.1693 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 84</span>| 762.44359 | 0.9999 | -0.9314 | -1.416 | -0.1734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9021 | -0.9130 | -0.2995 | -0.4152 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1389 | -0.8855 | -0.7244 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5550 | -0.6643 | -0.7689 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44359 | 96.99 | -2.886 | -4.253 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8301 | 1.268 | 0.9370 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.619 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44359</span> | 96.99 | 0.05580 | 0.01423 | 0.007647 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8301 | 1.268 | 0.9370 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.619 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -2.684 | -0.05996 | 0.05741 | -0.1839 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2433 | 0.07318 | -0.4825 | 0.3221 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8461 | -0.3440 | -0.8674 | -0.7797 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7318 | -0.7544 | -0.1758 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 85</span>| 762.44327 | 1.000 | -0.9314 | -1.416 | -0.1734 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9021 | -0.9130 | -0.2995 | -0.4153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1389 | -0.8855 | -0.7243 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5549 | -0.6642 | -0.7688 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44327 | 97.00 | -2.886 | -4.253 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8301 | 1.268 | 0.9370 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.619 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44327</span> | 97.00 | 0.05580 | 0.01423 | 0.007648 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8301 | 1.268 | 0.9370 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.619 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.433 | -0.03457 | 0.06633 | -0.1687 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1378 | 0.1478 | -0.5721 | 0.2715 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9861 | -0.3308 | -0.8969 | -0.7064 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4388 | -0.9204 | -0.1570 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 86</span>| 762.44310 | 0.9999 | -0.9314 | -1.416 | -0.1733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9021 | -0.9130 | -0.2994 | -0.4153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1388 | -0.8854 | -0.7242 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5549 | -0.6642 | -0.7688 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.4431 | 96.99 | -2.886 | -4.253 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8301 | 1.268 | 0.9371 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.619 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.4431</span> | 96.99 | 0.05580 | 0.01423 | 0.007648 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8301 | 1.268 | 0.9371 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.619 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -2.488 | -0.05983 | 0.05732 | -0.1840 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2388 | 0.07017 | -0.4805 | 0.5027 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8122 | -0.3072 | -0.8597 | -0.7873 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7191 | -0.5849 | -0.1893 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 87</span>| 762.44280 | 1.000 | -0.9314 | -1.416 | -0.1733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9021 | -0.9130 | -0.2994 | -0.4153 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1388 | -0.8854 | -0.7241 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5548 | -0.6641 | -0.7688 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.4428 | 97.00 | -2.886 | -4.253 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8301 | 1.268 | 0.9371 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.620 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.4428</span> | 97.00 | 0.05580 | 0.01423 | 0.007648 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8301 | 1.268 | 0.9371 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.620 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.618 | -0.03464 | 0.06615 | -0.1687 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1343 | 0.1439 | -0.4410 | 0.3116 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7529 | -0.3320 | -0.8865 | -0.6978 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4222 | -0.9084 | -0.1490 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 88</span>| 762.44259 | 0.9999 | -0.9314 | -1.416 | -0.1733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9021 | -0.9130 | -0.2994 | -0.4154 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1387 | -0.8854 | -0.7240 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5548 | -0.6640 | -0.7687 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44259 | 96.99 | -2.886 | -4.253 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8302 | 1.269 | 0.9371 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.620 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44259</span> | 96.99 | 0.05580 | 0.01423 | 0.007648 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8302 | 1.269 | 0.9371 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.620 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.481 | -0.03300 | 0.06550 | -0.1695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1475 | 0.1316 | -0.5909 | 0.2411 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9770 | -0.3768 | -0.8670 | -1.331 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4247 | -0.9107 | -0.1525 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 89</span>| 762.44225 | 1.000 | -0.9314 | -1.416 | -0.1733 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9021 | -0.9130 | -0.2993 | -0.4154 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1387 | -0.8853 | -0.7239 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5548 | -0.6639 | -0.7687 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44225 | 97.00 | -2.886 | -4.253 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8302 | 1.269 | 0.9372 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.620 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44225</span> | 97.00 | 0.05580 | 0.01423 | 0.007648 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8302 | 1.269 | 0.9372 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.620 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.420 | -0.03457 | 0.06572 | -0.1685 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1336 | 0.1386 | -0.4202 | 0.2852 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9190 | -0.3266 | -0.8656 | -0.6768 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4245 | -0.9083 | -0.1511 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 90</span>| 762.44213 | 0.9998 | -0.9314 | -1.416 | -0.1732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9021 | -0.9130 | -0.2993 | -0.4154 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1386 | -0.8853 | -0.7238 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5547 | -0.6639 | -0.7687 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44213 | 96.99 | -2.886 | -4.253 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8302 | 1.269 | 0.9373 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.620 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44213</span> | 96.99 | 0.05580 | 0.01423 | 0.007649 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7670 | 0.8302 | 1.269 | 0.9373 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.620 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -2.863 | -0.05945 | 0.05668 | -0.1838 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2350 | 0.05997 | -0.4163 | 0.3221 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8675 | -0.3570 | -0.8347 | -0.7546 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7945 | -0.5713 | -0.1981 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 91</span>| 762.44181 | 1.000 | -0.9314 | -1.416 | -0.1732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9021 | -0.9130 | -0.2993 | -0.4154 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1386 | -0.8853 | -0.7237 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5547 | -0.6638 | -0.7687 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44181 | 97.00 | -2.886 | -4.253 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7671 | 0.8302 | 1.269 | 0.9373 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.620 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44181</span> | 97.00 | 0.05580 | 0.01423 | 0.007649 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7671 | 0.8302 | 1.269 | 0.9373 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.620 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.253 | -0.03424 | 0.06574 | -0.1683 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1309 | 0.1341 | -0.5651 | 0.1807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.016 | -0.3557 | -0.8957 | -0.7064 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5151 | -0.5648 | -0.1753 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 92</span>| 762.44169 | 0.9999 | -0.9314 | -1.416 | -0.1732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9020 | -0.9130 | -0.2993 | -0.4154 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1385 | -0.8853 | -0.7236 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5547 | -0.6638 | -0.7687 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44169 | 96.99 | -2.886 | -4.253 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7671 | 0.8303 | 1.269 | 0.9374 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.620 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44169</span> | 96.99 | 0.05581 | 0.01423 | 0.007649 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7671 | 0.8303 | 1.269 | 0.9374 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.620 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -2.696 | -0.05943 | 0.05667 | -0.1838 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2311 | 0.05629 | -0.4589 | 0.3239 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8257 | -0.3368 | -0.8102 | -0.7513 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7185 | -0.5600 | -0.1932 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 93</span>| 762.44142 | 1.000 | -0.9314 | -1.416 | -0.1731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9020 | -0.9130 | -0.2992 | -0.4154 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1385 | -0.8852 | -0.7235 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5546 | -0.6637 | -0.7687 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44142 | 97.00 | -2.886 | -4.253 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7671 | 0.8303 | 1.269 | 0.9374 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.620 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44142</span> | 97.00 | 0.05581 | 0.01423 | 0.007649 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7671 | 0.8303 | 1.269 | 0.9374 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.620 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.335 | -0.03441 | 0.06556 | -0.1684 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1266 | 0.1302 | -0.6103 | 0.1783 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.044 | -0.3387 | -0.8638 | -1.338 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5275 | -0.5670 | -0.1757 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 94</span>| 762.44125 | 0.9999 | -0.9314 | -1.415 | -0.1731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9020 | -0.9131 | -0.2992 | -0.4154 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1384 | -0.8852 | -0.7234 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5545 | -0.6637 | -0.7687 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44125 | 96.99 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.042 | -1.970 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7671 | 0.8303 | 1.269 | 0.9375 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.620 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44125</span> | 96.99 | 0.05581 | 0.01423 | 0.007649 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7671 | 0.8303 | 1.269 | 0.9375 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.620 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -2.098 | -0.05964 | 0.05680 | -0.1834 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2254 | 0.05544 | -0.4561 | 0.3185 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8411 | -0.2737 | -0.7922 | -0.7469 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7250 | -0.5635 | -0.1902 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 95</span>| 762.44108 | 1.000 | -0.9314 | -1.415 | -0.1731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9020 | -0.9131 | -0.2992 | -0.4154 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1384 | -0.8852 | -0.7233 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5545 | -0.6636 | -0.7687 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44108 | 97.00 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.970 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7671 | 0.8303 | 1.269 | 0.9376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.620 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44108</span> | 97.00 | 0.05581 | 0.01423 | 0.007650 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7671 | 0.8303 | 1.269 | 0.9376 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.620 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 2.161 | -0.06174 | 0.05743 | -0.1824 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2028 | 0.06759 | -0.4445 | 0.3255 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8755 | -0.3449 | -0.7930 | -0.7294 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7121 | -0.5628 | -0.1899 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 96</span>| 762.44087 | 0.9999 | -0.9313 | -1.415 | -0.1731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9020 | -0.9131 | -0.2991 | -0.4155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1383 | -0.8852 | -0.7232 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5544 | -0.6636 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44087 | 96.99 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.970 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7671 | 0.8303 | 1.269 | 0.9376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.108 | 1.620 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44087</span> | 96.99 | 0.05581 | 0.01423 | 0.007650 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7671 | 0.8303 | 1.269 | 0.9376 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.108 | 1.620 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.8905 | -0.03259 | 0.06518 | -0.1692 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1290 | 0.1190 | -0.3929 | 0.3938 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7338 | -0.2959 | -0.8056 | -1.276 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4089 | -0.8806 | -0.1497 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 97</span>| 762.44057 | 1.000 | -0.9313 | -1.415 | -0.1731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9020 | -0.9131 | -0.2991 | -0.4155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1383 | -0.8852 | -0.7232 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5544 | -0.6635 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44057 | 97.00 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.970 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7672 | 0.8304 | 1.269 | 0.9377 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.620 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44057</span> | 97.00 | 0.05581 | 0.01423 | 0.007650 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7672 | 0.8304 | 1.269 | 0.9377 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.620 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.554 | -0.03385 | 0.06512 | -0.1686 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1157 | 0.1237 | -0.6002 | 0.2113 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9800 | -0.3598 | -0.8363 | -0.6768 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4936 | -0.5534 | -0.1651 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 98</span>| 762.44050 | 0.9998 | -0.9313 | -1.415 | -0.1730 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9020 | -0.9131 | -0.2991 | -0.4155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1382 | -0.8851 | -0.7231 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5543 | -0.6635 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.4405 | 96.98 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.970 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7672 | 0.8304 | 1.270 | 0.9378 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.620 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.4405</span> | 96.98 | 0.05581 | 0.01423 | 0.007650 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.676 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7672 | 0.8304 | 1.270 | 0.9378 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.620 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -3.014 | -0.05852 | 0.05608 | -0.1841 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2187 | 0.04463 | -0.4314 | 0.3139 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8150 | -0.2938 | -0.7775 | -0.7094 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7099 | -0.5560 | -0.1738 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 99</span>| 762.44022 | 1.000 | -0.9313 | -1.415 | -0.1730 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9020 | -0.9131 | -0.2990 | -0.4155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1382 | -0.8851 | -0.7230 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5543 | -0.6634 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44022 | 97.00 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.970 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7672 | 0.8304 | 1.270 | 0.9378 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.620 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44022</span> | 97.00 | 0.05581 | 0.01423 | 0.007650 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7672 | 0.8304 | 1.270 | 0.9378 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.620 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.178 | -0.03363 | 0.06507 | -0.1685 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1131 | 0.1194 | -0.3125 | 0.3718 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7445 | -0.2864 | -0.7962 | -1.246 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4203 | -0.8863 | -0.1505 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 100</span>| 762.44004 | 0.9999 | -0.9313 | -1.415 | -0.1730 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9020 | -0.9131 | -0.2990 | -0.4155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1381 | -0.8851 | -0.7229 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5542 | -0.6634 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44004 | 96.99 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.970 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7672 | 0.8304 | 1.270 | 0.9379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.621 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44004</span> | 96.99 | 0.05581 | 0.01423 | 0.007651 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7672 | 0.8304 | 1.270 | 0.9379 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.621 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -2.333 | -0.05890 | 0.05611 | -0.1836 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2128 | 0.04378 | -0.4032 | 0.2695 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7985 | -0.3486 | -0.7543 | -0.7042 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7059 | -0.5388 | -0.1896 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 101</span>| 762.43981 | 1.000 | -0.9313 | -1.415 | -0.1729 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9020 | -0.9131 | -0.2990 | -0.4155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1381 | -0.8850 | -0.7228 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5542 | -0.6633 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43981 | 97.00 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.970 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7672 | 0.8305 | 1.270 | 0.9379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.621 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43981</span> | 97.00 | 0.05581 | 0.01423 | 0.007651 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7672 | 0.8305 | 1.270 | 0.9379 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.621 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.028 | -0.03404 | 0.06496 | -0.1681 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1065 | 0.1184 | -0.4168 | 0.2498 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9058 | -0.3159 | -0.7884 | -1.255 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4119 | -0.8796 | -0.1400 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 102</span>| 762.43962 | 0.9999 | -0.9313 | -1.415 | -0.1729 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9020 | -0.9131 | -0.2990 | -0.4155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1380 | -0.8850 | -0.7226 | -1.070 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5542 | -0.6633 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43962 | 96.99 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.970 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7672 | 0.8305 | 1.270 | 0.9380 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.621 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43962</span> | 96.99 | 0.05581 | 0.01423 | 0.007651 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7672 | 0.8305 | 1.270 | 0.9380 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.621 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -1.383 | -0.05944 | 0.05652 | -0.1827 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2071 | 0.04458 | -0.4356 | 0.2597 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6953 | -0.3158 | -0.7477 | -0.7025 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6996 | -0.5341 | -0.1909 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 103</span>| 762.43950 | 1.000 | -0.9313 | -1.415 | -0.1729 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9020 | -0.9131 | -0.2989 | -0.4155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1380 | -0.8850 | -0.7226 | -1.069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5541 | -0.6632 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.4395 | 97.00 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.970 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7672 | 0.8305 | 1.270 | 0.9381 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.621 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.4395</span> | 97.00 | 0.05581 | 0.01423 | 0.007651 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7672 | 0.8305 | 1.270 | 0.9381 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.621 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 2.549 | -0.06132 | 0.05688 | -0.1819 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1843 | 0.05521 | -0.4401 | 0.2903 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8733 | -0.3487 | -0.7274 | -0.6827 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7019 | -0.6971 | -0.1749 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 104</span>| 762.43927 | 0.9999 | -0.9313 | -1.415 | -0.1728 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9019 | -0.9131 | -0.2989 | -0.4155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1379 | -0.8849 | -0.7225 | -1.069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5540 | -0.6632 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43927 | 96.99 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.970 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7672 | 0.8305 | 1.270 | 0.9381 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.621 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43927</span> | 96.99 | 0.05581 | 0.01423 | 0.007652 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7672 | 0.8305 | 1.270 | 0.9381 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.621 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.3204 | -0.03231 | 0.06473 | -0.1685 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1091 | 0.1080 | -0.5711 | 0.1928 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9793 | -0.3347 | -0.7909 | -0.6262 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4835 | -0.5228 | -0.1576 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 105</span>| 762.43906 | 0.9999 | -0.9313 | -1.415 | -0.1728 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9019 | -0.9131 | -0.2988 | -0.4156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1378 | -0.8849 | -0.7224 | -1.069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5540 | -0.6631 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43906 | 96.99 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.970 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7673 | 0.8306 | 1.270 | 0.9382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.621 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43906</span> | 96.99 | 0.05581 | 0.01423 | 0.007652 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7673 | 0.8306 | 1.270 | 0.9382 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.621 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.5587 | -0.06228 | 0.03863 | -0.1950 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1923 | 0.02120 | -0.5716 | 0.1497 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.063 | -0.3909 | -0.8335 | -0.6812 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5632 | -0.5998 | -0.1754 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 106</span>| 762.43877 | 1.000 | -0.9313 | -1.415 | -0.1728 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9019 | -0.9131 | -0.2987 | -0.4156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1376 | -0.8848 | -0.7222 | -1.069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5539 | -0.6630 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43877 | 97.01 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.970 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7673 | 0.8306 | 1.271 | 0.9383 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.621 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43877</span> | 97.01 | 0.05581 | 0.01423 | 0.007652 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1224 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7673 | 0.8306 | 1.271 | 0.9383 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.621 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.291 | -0.03430 | 0.06450 | -0.1679 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07426 | 0.1162 | -0.3841 | 0.3404 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7902 | -0.2891 | -0.7321 | -1.195 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4125 | -0.8681 | -0.1491 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 107</span>| 762.43824 | 0.9999 | -0.9312 | -1.415 | -0.1727 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9019 | -0.9131 | -0.2986 | -0.4155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1375 | -0.8848 | -0.7220 | -1.069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5537 | -0.6629 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43824 | 96.99 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.970 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7674 | 0.8307 | 1.271 | 0.9384 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.621 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43824</span> | 96.99 | 0.05581 | 0.01423 | 0.007653 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1223 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7674 | 0.8307 | 1.271 | 0.9384 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.621 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 0.2143 | -0.03008 | 0.06460 | -0.1683 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09063 | 0.09635 | -0.3662 | 0.3094 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8321 | -0.3196 | -0.7371 | -1.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3971 | -0.8686 | -0.1637 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 108</span>| 762.43774 | 0.9999 | -0.9312 | -1.415 | -0.1727 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9019 | -0.9132 | -0.2986 | -0.4156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1373 | -0.8847 | -0.7219 | -1.069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5537 | -0.6628 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43774 | 96.99 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.970 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7674 | 0.8307 | 1.271 | 0.9387 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.621 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43774</span> | 96.99 | 0.05581 | 0.01423 | 0.007653 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1149 | 0.1223 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7674 | 0.8307 | 1.271 | 0.9387 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.621 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.093 | -0.02921 | 0.06344 | -0.1689 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09286 | 0.08671 | -0.5952 | 0.1702 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9595 | -0.3554 | -0.7565 | -1.200 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4954 | -0.5121 | -0.1787 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 109</span>| 762.43688 | 1.000 | -0.9312 | -1.415 | -0.1726 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9018 | -0.9132 | -0.2983 | -0.4156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1370 | -0.8845 | -0.7215 | -1.069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5534 | -0.6626 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43688 | 97.00 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.970 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7675 | 0.8309 | 1.271 | 0.9392 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.622 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43688</span> | 97.00 | 0.05581 | 0.01423 | 0.007654 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7675 | 0.8309 | 1.271 | 0.9392 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.622 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.631 | -0.02940 | 0.06277 | -0.1685 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.07102 | 0.08313 | -0.3454 | 0.3850 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6531 | -0.2578 | -0.6895 | -0.5122 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3743 | -0.8283 | -0.1580 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 110</span>| 762.43834 | 0.9996 | -0.9312 | -1.415 | -0.1725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9018 | -0.9132 | -0.2981 | -0.4156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1367 | -0.8844 | -0.7212 | -1.068 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5532 | -0.6623 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43834 | 96.96 | -2.886 | -4.252 | -4.872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7676 | 0.8310 | 1.272 | 0.9395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.622 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43834</span> | 96.96 | 0.05582 | 0.01423 | 0.007654 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7676 | 0.8310 | 1.272 | 0.9395 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.622 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 111</span>| 762.43689 | 0.9998 | -0.9312 | -1.415 | -0.1726 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9018 | -0.9132 | -0.2983 | -0.4156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1369 | -0.8845 | -0.7215 | -1.068 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5534 | -0.6625 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43689 | 96.98 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7675 | 0.8309 | 1.271 | 0.9392 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.622 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43689</span> | 96.98 | 0.05581 | 0.01423 | 0.007654 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7675 | 0.8309 | 1.271 | 0.9392 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.622 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 112</span>| 762.43680 | 0.9999 | -0.9312 | -1.415 | -0.1726 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9018 | -0.9132 | -0.2983 | -0.4156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1369 | -0.8845 | -0.7215 | -1.068 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5534 | -0.6625 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.4368 | 96.99 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7675 | 0.8309 | 1.271 | 0.9392 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.622 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.4368</span> | 96.99 | 0.05581 | 0.01423 | 0.007654 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.677 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7675 | 0.8309 | 1.271 | 0.9392 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.622 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -1.290 | -0.05938 | 0.05401 | -0.1835 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1692 | 0.01048 | -0.3277 | 0.2904 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7941 | -0.3134 | -0.6583 | -0.6001 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6796 | -0.4935 | -0.1985 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 113</span>| 762.43669 | 1.000 | -0.9312 | -1.415 | -0.1726 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9018 | -0.9132 | -0.2983 | -0.4156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1369 | -0.8845 | -0.7215 | -1.068 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5534 | -0.6625 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43669 | 97.00 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7675 | 0.8309 | 1.271 | 0.9393 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.622 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43669</span> | 97.00 | 0.05581 | 0.01423 | 0.007654 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7675 | 0.8309 | 1.271 | 0.9393 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.622 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 0.7530 | -0.06037 | 0.05419 | -0.1831 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1576 | 0.01628 | -0.3476 | 0.2756 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7793 | -0.2989 | -0.6525 | -0.5921 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6883 | -0.6531 | -0.1740 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 114</span>| 762.43657 | 0.9999 | -0.9312 | -1.415 | -0.1726 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9018 | -0.9132 | -0.2983 | -0.4156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1369 | -0.8845 | -0.7214 | -1.068 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5533 | -0.6625 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43657 | 96.99 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7675 | 0.8309 | 1.271 | 0.9393 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.622 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43657</span> | 96.99 | 0.05581 | 0.01423 | 0.007654 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7675 | 0.8309 | 1.271 | 0.9393 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.622 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -0.6017 | -0.05955 | 0.05380 | -0.1836 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1610 | 0.01132 | -0.3419 | 0.2571 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5470 | -0.3329 | -0.6445 | -0.5910 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6872 | -0.4903 | -0.2027 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 115</span>| 762.43648 | 1.000 | -0.9312 | -1.415 | -0.1725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9018 | -0.9132 | -0.2983 | -0.4156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1368 | -0.8845 | -0.7214 | -1.068 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5533 | -0.6625 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43648 | 97.00 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7676 | 0.8309 | 1.271 | 0.9393 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.622 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43648</span> | 97.00 | 0.05582 | 0.01423 | 0.007654 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7676 | 0.8309 | 1.271 | 0.9393 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.622 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 0.6240 | -0.06006 | 0.05383 | -0.1835 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1526 | 0.01440 | -0.3766 | 0.2889 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6299 | -0.2748 | -0.6469 | -0.5850 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6758 | -0.4890 | -0.2032 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 116</span>| 762.43640 | 0.9999 | -0.9312 | -1.415 | -0.1725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9018 | -0.9132 | -0.2982 | -0.4157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1368 | -0.8845 | -0.7214 | -1.068 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5533 | -0.6624 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.4364 | 96.99 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7676 | 0.8309 | 1.271 | 0.9394 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.622 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.4364</span> | 96.99 | 0.05582 | 0.01423 | 0.007654 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7676 | 0.8309 | 1.271 | 0.9394 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.622 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -0.6134 | -0.05930 | 0.05345 | -0.1840 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1552 | 0.009772 | -0.3787 | 0.2674 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7680 | -0.3180 | -0.6329 | -0.5960 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6746 | -0.4920 | -0.1810 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 117</span>| 762.43627 | 1.000 | -0.9312 | -1.415 | -0.1725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9018 | -0.9132 | -0.2982 | -0.4157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1367 | -0.8844 | -0.7213 | -1.068 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5532 | -0.6624 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43627 | 97.00 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7676 | 0.8310 | 1.272 | 0.9394 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.109 | 1.622 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43627</span> | 97.00 | 0.05582 | 0.01423 | 0.007654 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7676 | 0.8310 | 1.272 | 0.9394 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.109 | 1.622 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 118</span>| 762.43603 | 1.000 | -0.9312 | -1.415 | -0.1725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9018 | -0.9132 | -0.2982 | -0.4157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1367 | -0.8844 | -0.7213 | -1.068 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5532 | -0.6624 | -0.7685 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43603 | 97.00 | -2.886 | -4.252 | -4.873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7676 | 0.8310 | 1.272 | 0.9395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.110 | 1.622 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43603</span> | 97.00 | 0.05582 | 0.01423 | 0.007654 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.677 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7676 | 0.8310 | 1.272 | 0.9395 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.110 | 1.622 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 119</span>| 762.43566 | 1.000 | -0.9311 | -1.415 | -0.1724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9017 | -0.9132 | -0.2979 | -0.4156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1365 | -0.8844 | -0.7210 | -1.068 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5529 | -0.6622 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43566 | 97.00 | -2.886 | -4.252 | -4.872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.678 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7677 | 0.8310 | 1.272 | 0.9398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.110 | 1.622 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43566</span> | 97.00 | 0.05582 | 0.01424 | 0.007655 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.678 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7677 | 0.8310 | 1.272 | 0.9398 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.110 | 1.622 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.185 | -0.02630 | 0.06197 | -0.1690 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.04569 | 0.06766 | -0.1965 | 0.3760 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8361 | -0.3368 | -0.6862 | -1.092 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4397 | -0.4588 | -0.1669 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 120</span>| 762.43438 | 1.000 | -0.9309 | -1.415 | -0.1720 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9017 | -0.9133 | -0.2975 | -0.4155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1356 | -0.8841 | -0.7203 | -1.067 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5523 | -0.6619 | -0.7688 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43438 | 97.00 | -2.885 | -4.252 | -4.872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.678 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7679 | 0.8313 | 1.273 | 0.9407 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.110 | 1.623 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43438</span> | 97.00 | 0.05583 | 0.01424 | 0.007658 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.678 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7679 | 0.8313 | 1.273 | 0.9407 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.110 | 1.623 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.044 | -0.02148 | 0.06186 | -0.1669 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.02022 | 0.04124 | -0.2960 | 0.3008 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7013 | -0.2777 | -0.6002 | -0.9685 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3508 | -0.7933 | -0.1801 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 121</span>| 762.45137 | 0.9988 | -0.9307 | -1.414 | -0.1714 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9015 | -0.9135 | -0.2962 | -0.4154 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1345 | -0.8836 | -0.7191 | -1.066 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5512 | -0.6609 | -0.7687 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.45137 | 96.89 | -2.885 | -4.251 | -4.871 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.040 | -1.971 | 2.679 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7682 | 0.8316 | 1.274 | 0.9425 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.111 | 1.624 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.45137</span> | 96.89 | 0.05584 | 0.01425 | 0.007663 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.679 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7682 | 0.8316 | 1.274 | 0.9425 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.111 | 1.624 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 122</span>| 762.43671 | 0.9995 | -0.9309 | -1.415 | -0.1720 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9017 | -0.9133 | -0.2974 | -0.4156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1355 | -0.8840 | -0.7202 | -1.067 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5523 | -0.6617 | -0.7687 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43671 | 96.95 | -2.885 | -4.252 | -4.872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.678 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7679 | 0.8313 | 1.273 | 0.9409 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.110 | 1.623 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43671</span> | 96.95 | 0.05583 | 0.01424 | 0.007658 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.678 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7679 | 0.8313 | 1.273 | 0.9409 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.110 | 1.623 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 123</span>| 762.43423 | 0.9999 | -0.9309 | -1.415 | -0.1720 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9017 | -0.9133 | -0.2975 | -0.4155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1356 | -0.8841 | -0.7202 | -1.067 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5523 | -0.6618 | -0.7688 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43423 | 96.99 | -2.885 | -4.252 | -4.872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.678 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7679 | 0.8313 | 1.273 | 0.9408 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.110 | 1.623 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43423</span> | 96.99 | 0.05583 | 0.01424 | 0.007658 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.678 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7679 | 0.8313 | 1.273 | 0.9408 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.110 | 1.623 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.5170 | -0.01948 | 0.06121 | -0.1679 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.03590 | 0.02978 | -0.3666 | 0.2413 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7570 | -0.2885 | -0.6014 | -0.3882 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3403 | -0.8088 | -0.1895 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 124</span>| 762.43413 | 0.9999 | -0.9309 | -1.415 | -0.1720 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9017 | -0.9133 | -0.2974 | -0.4155 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1356 | -0.8840 | -0.7202 | -1.067 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5523 | -0.6618 | -0.7687 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43413 | 96.99 | -2.885 | -4.252 | -4.872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.678 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7679 | 0.8313 | 1.273 | 0.9408 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.110 | 1.623 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43413</span> | 96.99 | 0.05583 | 0.01424 | 0.007658 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.678 | 0.8732 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7679 | 0.8313 | 1.273 | 0.9408 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.110 | 1.623 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 0.1909 | -0.05140 | 0.05299 | -0.1819 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1179 | -0.03105 | -0.2940 | 0.3229 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7019 | -0.3052 | -0.5670 | -0.4669 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5306 | -0.6218 | -0.1957 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 125</span>| 762.43390 | 0.9999 | -0.9309 | -1.415 | -0.1719 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9016 | -0.9133 | -0.2974 | -0.4156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1354 | -0.8840 | -0.7201 | -1.067 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5522 | -0.6617 | -0.7687 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.4339 | 96.99 | -2.885 | -4.252 | -4.872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.678 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7679 | 0.8313 | 1.273 | 0.9409 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.110 | 1.623 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.4339</span> | 96.99 | 0.05583 | 0.01424 | 0.007659 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.678 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7679 | 0.8313 | 1.273 | 0.9409 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.110 | 1.623 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.114 | -0.06011 | 0.02465 | -0.2051 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1552 | -0.09095 | -0.5672 | 0.02114 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8958 | -0.3459 | -0.7191 | -0.5113 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5884 | -0.9931 | -0.1777 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 126</span>| 762.43345 | 0.9998 | -0.9309 | -1.415 | -0.1719 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9016 | -0.9133 | -0.2973 | -0.4157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1352 | -0.8839 | -0.7199 | -1.067 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5520 | -0.6614 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43345 | 96.98 | -2.885 | -4.252 | -4.872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.678 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7680 | 0.8314 | 1.273 | 0.9411 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.110 | 1.623 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43345</span> | 96.98 | 0.05583 | 0.01424 | 0.007659 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.678 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7680 | 0.8314 | 1.273 | 0.9411 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.110 | 1.623 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.199 | -0.01754 | 0.05950 | -0.1696 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.02539 | 0.02275 | -0.4402 | 0.1842 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6341 | -0.3071 | -0.5996 | -0.4400 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3790 | -0.4298 | -0.1917 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 127</span>| 762.44283 | 1.001 | -0.9309 | -1.415 | -0.1718 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9016 | -0.9133 | -0.2971 | -0.4158 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1349 | -0.8837 | -0.7196 | -1.067 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5519 | -0.6613 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.44283 | 97.07 | -2.885 | -4.252 | -4.872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.679 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7681 | 0.8315 | 1.273 | 0.9413 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.111 | 1.623 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.44283</span> | 97.07 | 0.05583 | 0.01424 | 0.007660 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.679 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7681 | 0.8315 | 1.273 | 0.9413 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.111 | 1.623 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 128</span>| 762.43327 | 0.9999 | -0.9309 | -1.415 | -0.1719 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9016 | -0.9133 | -0.2972 | -0.4157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1352 | -0.8839 | -0.7199 | -1.067 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5520 | -0.6614 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43327 | 96.99 | -2.885 | -4.252 | -4.872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.678 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7680 | 0.8314 | 1.273 | 0.9411 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.111 | 1.623 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43327</span> | 96.99 | 0.05583 | 0.01424 | 0.007659 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.678 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7680 | 0.8314 | 1.273 | 0.9411 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.111 | 1.623 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 0.8515 | -0.01931 | 0.05976 | -0.1688 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.01220 | 0.03131 | -0.3546 | 0.1731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7860 | -0.3212 | -0.6045 | -0.3881 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4306 | -0.4501 | -0.2053 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 129</span>| 762.43323 | 0.9999 | -0.9309 | -1.415 | -0.1718 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9016 | -0.9133 | -0.2972 | -0.4157 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1351 | -0.8838 | -0.7198 | -1.067 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5520 | -0.6614 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43323 | 96.99 | -2.885 | -4.252 | -4.872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.678 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7680 | 0.8315 | 1.273 | 0.9411 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.111 | 1.623 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43323</span> | 96.99 | 0.05583 | 0.01424 | 0.007659 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.678 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7680 | 0.8315 | 1.273 | 0.9411 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.111 | 1.623 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -1.674 | -0.04944 | 0.05118 | -0.1837 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1087 | -0.03856 | -0.2663 | 0.2605 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5380 | -0.2892 | -0.5353 | -0.4315 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5100 | -0.4392 | -0.2141 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 130</span>| 762.43310 | 0.9999 | -0.9309 | -1.415 | -0.1718 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9016 | -0.9133 | -0.2972 | -0.4158 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1351 | -0.8838 | -0.7198 | -1.067 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5519 | -0.6614 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.4331 | 96.99 | -2.885 | -4.252 | -4.872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.678 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7680 | 0.8315 | 1.273 | 0.9412 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.111 | 1.623 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.4331</span> | 96.99 | 0.05583 | 0.01424 | 0.007660 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.678 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7680 | 0.8315 | 1.273 | 0.9412 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.111 | 1.623 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | 0.5279 | -0.05046 | 0.05140 | -0.1826 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.09758 | -0.03208 | -0.2630 | 0.2539 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6786 | -0.2981 | -0.5397 | -0.4304 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4336 | -0.5936 | -0.1903 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 131</span>| 762.43324 | 0.9999 | -0.9309 | -1.415 | -0.1718 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9016 | -0.9133 | -0.2972 | -0.4158 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1351 | -0.8838 | -0.7198 | -1.067 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5519 | -0.6614 | -0.7686 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | U| 762.43324 | 96.99 | -2.885 | -4.252 | -4.872 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -2.041 | -1.971 | 2.678 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7680 | 0.8315 | 1.273 | 0.9412 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.111 | 1.623 | 1.478 |...........|</span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 762.43324</span> | 96.99 | 0.05583 | 0.01424 | 0.007660 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1150 | 0.1223 | 2.678 | 0.8731 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7680 | 0.8315 | 1.273 | 0.9412 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.111 | 1.623 | 1.478 |...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>initial ETAs were nudged; (can control by foceiControl(etaNudge=., etaNudge2=))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>ETAs were reset to zero during optimization; (Can control by foceiControl(resetEtaP=.))</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>last objective function was not at minimum, possible problems in optimization</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>using R matrix to calculate covariance, can check sandwich or S matrix with $covRS and $covS</span> +<span class="r-wrn co"><span class="r-pr">#></span> <span class="warning">Warning: </span>gradient problems with initial estimate and covariance; see $scaleInfo</span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> + </div> + <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> +</div> + + + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> +</div> + +<div class="pkgdown"> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> +</div> + + </footer></div> + + + + + + + </body></html> + diff --git a/docs/reference/nobs.mkinfit.html b/docs/reference/nobs.mkinfit.html index 6b9948c3..0fc1ca7c 100644 --- a/docs/reference/nobs.mkinfit.html +++ b/docs/reference/nobs.mkinfit.html @@ -1,67 +1,12 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Number of observations on which an mkinfit object was fitted — nobs.mkinfit • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Number of observations on which an mkinfit object was fitted — nobs.mkinfit" /> -<meta property="og:description" content="Number of observations on which an mkinfit object was fitted" /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Number of observations on which an mkinfit object was fitted — nobs.mkinfit • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Number of observations on which an mkinfit object was fitted — nobs.mkinfit"><meta property="og:description" content="Number of observations on which an mkinfit object was fitted"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -72,13 +17,12 @@ </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -87,8 +31,7 @@ <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -98,6 +41,9 @@ <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -112,34 +58,27 @@ <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Number of observations on which an mkinfit object was fitted</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/nobs.mkinfit.R'><code>R/nobs.mkinfit.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/nobs.mkinfit.R" class="external-link"><code>R/nobs.mkinfit.R</code></a></small> <div class="hidden name"><code>nobs.mkinfit.Rd</code></div> </div> @@ -147,51 +86,44 @@ <p>Number of observations on which an mkinfit object was fitted</p> </div> - <pre class="usage"><span class='co'># S3 method for mkinfit</span> -<span class='fu'><a href='https://rdrr.io/r/stats/nobs.html'>nobs</a></span><span class='op'>(</span><span class='va'>object</span>, <span class='va'>...</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>An mkinfit object</p></td> - </tr> - <tr> - <th>...</th> - <td><p>For compatibility with the generic method</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for mkinfit</span> +<span class="fu"><a href="https://rdrr.io/r/stats/nobs.html" class="external-link">nobs</a></span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>An mkinfit object</p></dd> +<dt>...</dt> +<dd><p>For compatibility with the generic method</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The number of rows in the data included in the mkinfit object</p> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/parms.html b/docs/reference/parms.html index b4346b13..00726a1d 100644 --- a/docs/reference/parms.html +++ b/docs/reference/parms.html @@ -1,69 +1,14 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Extract model parameters from mkinfit models — parms • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Extract model parameters from mkinfit models — parms" /> -<meta property="og:description" content="This function always returns degradation model parameters as well as error +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Extract model parameters from mkinfit models — parms • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Extract model parameters from mkinfit models — parms"><meta property="og:description" content="This function always returns degradation model parameters as well as error model parameters, in order to avoid working with a fitted model without -considering the error structure that was assumed for the fit." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +considering the error structure that was assumed for the fit."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -74,13 +19,12 @@ considering the error structure that was assumed for the fit." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -89,8 +33,7 @@ considering the error structure that was assumed for the fit." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -100,6 +43,9 @@ considering the error structure that was assumed for the fit." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -114,34 +60,27 @@ considering the error structure that was assumed for the fit." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Extract model parameters from mkinfit models</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/parms.mkinfit.R'><code>R/parms.mkinfit.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/parms.mkinfit.R" class="external-link"><code>R/parms.mkinfit.R</code></a></small> <div class="hidden name"><code>parms.Rd</code></div> </div> @@ -151,148 +90,147 @@ model parameters, in order to avoid working with a fitted model without considering the error structure that was assumed for the fit.</p> </div> - <pre class="usage"><span class='fu'>parms</span><span class='op'>(</span><span class='va'>object</span>, <span class='va'>...</span><span class='op'>)</span> - -<span class='co'># S3 method for mkinfit</span> -<span class='fu'>parms</span><span class='op'>(</span><span class='va'>object</span>, transformed <span class='op'>=</span> <span class='cn'>FALSE</span>, <span class='va'>...</span><span class='op'>)</span> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">parms</span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span><span class="op">)</span> -<span class='co'># S3 method for mmkin</span> -<span class='fu'>parms</span><span class='op'>(</span><span class='va'>object</span>, transformed <span class='op'>=</span> <span class='cn'>FALSE</span>, <span class='va'>...</span><span class='op'>)</span></pre> +<span class="co"># S3 method for mkinfit</span> +<span class="fu">parms</span><span class="op">(</span><span class="va">object</span>, transformed <span class="op">=</span> <span class="cn">FALSE</span>, <span class="va">...</span><span class="op">)</span> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>A fitted model object. Methods are implemented for -<code><a href='mkinfit.html'>mkinfit()</a></code> objects and for <code><a href='mmkin.html'>mmkin()</a></code> objects.</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Not used</p></td> - </tr> - <tr> - <th>transformed</th> - <td><p>Should the parameters be returned -as used internally during the optimisation?</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> +<span class="co"># S3 method for mmkin</span> +<span class="fu">parms</span><span class="op">(</span><span class="va">object</span>, transformed <span class="op">=</span> <span class="cn">FALSE</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>A fitted model object. Methods are implemented for +<code><a href="mkinfit.html">mkinfit()</a></code> objects and for <code><a href="mmkin.html">mmkin()</a></code> objects.</p></dd> +<dt>...</dt> +<dd><p>Not used</p></dd> +<dt>transformed</dt> +<dd><p>Should the parameters be returned +as used internally during the optimisation?</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>For mkinfit objects, a numeric vector of fitted model parameters. For mmkin row objects, a matrix with the parameters with a row for each dataset. If the mmkin object has more than one row, a list of such matrices is returned.</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='co'># mkinfit objects</span> -<span class='va'>fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='va'>FOCUS_2006_C</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'>parms</span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span> -</div><div class='output co'>#> parent_0 k_parent sigma -#> 82.4921598 0.3060633 4.6730124 </div><div class='input'><span class='fu'>parms</span><span class='op'>(</span><span class='va'>fit</span>, transformed <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> parent_0 log_k_parent sigma -#> 82.492160 -1.183963 4.673012 </div><div class='input'> -<span class='co'># mmkin objects</span> -<span class='va'>ds</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/lapply.html'>lapply</a></span><span class='op'>(</span><span class='va'>experimental_data_for_UBA_2019</span><span class='op'>[</span><span class='fl'>6</span><span class='op'>:</span><span class='fl'>10</span><span class='op'>]</span>, - <span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='fu'><a href='https://rdrr.io/r/base/subset.html'>subset</a></span><span class='op'>(</span><span class='va'>x</span><span class='op'>$</span><span class='va'>data</span><span class='op'>[</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"name"</span>, <span class='st'>"time"</span>, <span class='st'>"value"</span><span class='op'>)</span><span class='op'>]</span><span class='op'>)</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/names.html'>names</a></span><span class='op'>(</span><span class='va'>ds</span><span class='op'>)</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/paste.html'>paste</a></span><span class='op'>(</span><span class='st'>"Dataset"</span>, <span class='fl'>6</span><span class='op'>:</span><span class='fl'>10</span><span class='op'>)</span> -<span class='co'># \dontrun{</span> -<span class='va'>fits</span> <span class='op'><-</span> <span class='fu'><a href='mmkin.html'>mmkin</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"FOMC"</span>, <span class='st'>"DFOP"</span><span class='op'>)</span>, <span class='va'>ds</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, cores <span class='op'>=</span> <span class='fl'>1</span><span class='op'>)</span> -<span class='fu'>parms</span><span class='op'>(</span><span class='va'>fits</span><span class='op'>[</span><span class='st'>"SFO"</span>, <span class='op'>]</span><span class='op'>)</span> -</div><div class='output co'>#> Dataset 6 Dataset 7 Dataset 8 Dataset 9 Dataset 10 -#> parent_0 88.52275400 82.666781678 86.8547308 91.7779306 82.14809450 -#> k_parent 0.05794659 0.009647805 0.2102974 0.1232258 0.00720421 -#> sigma 5.15274487 7.040168584 3.6769645 6.4669234 6.50457673</div><div class='input'><span class='fu'>parms</span><span class='op'>(</span><span class='va'>fits</span><span class='op'>[</span>, <span class='fl'>2</span><span class='op'>]</span><span class='op'>)</span> -</div><div class='output co'>#> $SFO -#> Dataset 7 -#> parent_0 82.666781678 -#> k_parent 0.009647805 -#> sigma 7.040168584 -#> -#> $FOMC -#> Dataset 7 -#> parent_0 92.6837649 -#> alpha 0.4967832 -#> beta 14.1451255 -#> sigma 1.9167519 -#> -#> $DFOP -#> Dataset 7 -#> parent_0 91.058971589 -#> k1 0.044946770 -#> k2 0.002868336 -#> g 0.526942415 -#> sigma 2.221302196 -#> </div><div class='input'><span class='fu'>parms</span><span class='op'>(</span><span class='va'>fits</span><span class='op'>)</span> -</div><div class='output co'>#> $SFO -#> Dataset 6 Dataset 7 Dataset 8 Dataset 9 Dataset 10 -#> parent_0 88.52275400 82.666781678 86.8547308 91.7779306 82.14809450 -#> k_parent 0.05794659 0.009647805 0.2102974 0.1232258 0.00720421 -#> sigma 5.15274487 7.040168584 3.6769645 6.4669234 6.50457673 -#> -#> $FOMC -#> Dataset 6 Dataset 7 Dataset 8 Dataset 9 Dataset 10 -#> parent_0 95.558575 92.6837649 90.719787 98.383939 94.8481459 -#> alpha 1.338667 0.4967832 1.639099 1.074460 0.2805272 -#> beta 13.033315 14.1451255 5.007077 4.397126 6.9052224 -#> sigma 1.847671 1.9167519 1.066063 3.146056 1.6222778 -#> -#> $DFOP -#> Dataset 6 Dataset 7 Dataset 8 Dataset 9 Dataset 10 -#> parent_0 96.55213663 91.058971589 90.34509493 98.14858820 94.311323734 -#> k1 0.21954588 0.044946770 0.41232288 0.31697588 0.080663857 -#> k2 0.02957934 0.002868336 0.07581766 0.03260384 0.003425417 -#> g 0.44845068 0.526942415 0.66091967 0.65322767 0.342652880 -#> sigma 1.35690468 2.221302196 1.34169076 2.87159846 1.942067831 -#> </div><div class='input'><span class='fu'>parms</span><span class='op'>(</span><span class='va'>fits</span>, transformed <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> $SFO -#> Dataset 6 Dataset 7 Dataset 8 Dataset 9 Dataset 10 -#> parent_0 88.522754 82.666782 86.854731 91.777931 82.148094 -#> log_k_parent -2.848234 -4.641025 -1.559232 -2.093737 -4.933090 -#> sigma 5.152745 7.040169 3.676964 6.466923 6.504577 -#> -#> $FOMC -#> Dataset 6 Dataset 7 Dataset 8 Dataset 9 Dataset 10 -#> parent_0 95.5585751 92.6837649 90.7197870 98.38393897 94.848146 -#> log_alpha 0.2916741 -0.6996015 0.4941466 0.07181816 -1.271085 -#> log_beta 2.5675088 2.6493701 1.6108523 1.48095106 1.932278 -#> sigma 1.8476712 1.9167519 1.0660627 3.14605557 1.622278 -#> -#> $DFOP -#> Dataset 6 Dataset 7 Dataset 8 Dataset 9 Dataset 10 -#> parent_0 96.5521366 91.0589716 90.3450949 98.1485882 94.3113237 -#> log_k1 -1.5161940 -3.1022764 -0.8859486 -1.1489296 -2.5174647 -#> log_k2 -3.5206791 -5.8540232 -2.5794240 -3.4233253 -5.6765322 -#> g_qlogis -0.2069326 0.1078741 0.6673953 0.6332573 -0.6514943 -#> sigma 1.3569047 2.2213022 1.3416908 2.8715985 1.9420678 -#> </div><div class='input'><span class='co'># }</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="co"># mkinfit objects</span></span> +<span class="r-in"><span class="va">fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="va">FOCUS_2006_C</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu">parms</span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 k_parent sigma </span> +<span class="r-out co"><span class="r-pr">#></span> 82.4921598 0.3060633 4.6730124 </span> +<span class="r-in"><span class="fu">parms</span><span class="op">(</span><span class="va">fit</span>, transformed <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_k_parent sigma </span> +<span class="r-out co"><span class="r-pr">#></span> 82.492160 -1.183963 4.673012 </span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># mmkin objects</span></span> +<span class="r-in"><span class="va">ds</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="va">experimental_data_for_UBA_2019</span><span class="op">[</span><span class="fl">6</span><span class="op">:</span><span class="fl">10</span><span class="op">]</span>,</span> +<span class="r-in"> <span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu"><a href="https://rdrr.io/r/base/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">x</span><span class="op">$</span><span class="va">data</span><span class="op">[</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"name"</span>, <span class="st">"time"</span>, <span class="st">"value"</span><span class="op">)</span><span class="op">]</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">ds</span><span class="op">)</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste</a></span><span class="op">(</span><span class="st">"Dataset"</span>, <span class="fl">6</span><span class="op">:</span><span class="fl">10</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="va">fits</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"FOMC"</span>, <span class="st">"DFOP"</span><span class="op">)</span>, <span class="va">ds</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, cores <span class="op">=</span> <span class="fl">1</span><span class="op">)</span></span> +<span class="r-in"><span class="fu">parms</span><span class="op">(</span><span class="va">fits</span><span class="op">[</span><span class="st">"SFO"</span>, <span class="op">]</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Dataset 6 Dataset 7 Dataset 8 Dataset 9 Dataset 10</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 88.52275400 82.666781678 86.8547308 91.7779306 82.14809450</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.05794659 0.009647805 0.2102974 0.1232258 0.00720421</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 5.15274487 7.040168584 3.6769645 6.4669234 6.50457673</span> +<span class="r-in"><span class="fu">parms</span><span class="op">(</span><span class="va">fits</span><span class="op">[</span>, <span class="fl">2</span><span class="op">]</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> $SFO</span> +<span class="r-out co"><span class="r-pr">#></span> Dataset 7</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 82.666781678</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.009647805</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 7.040168584</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $FOMC</span> +<span class="r-out co"><span class="r-pr">#></span> Dataset 7</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 92.6837649</span> +<span class="r-out co"><span class="r-pr">#></span> alpha 0.4967832</span> +<span class="r-out co"><span class="r-pr">#></span> beta 14.1451255</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 1.9167519</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $DFOP</span> +<span class="r-out co"><span class="r-pr">#></span> Dataset 7</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 91.058971589</span> +<span class="r-out co"><span class="r-pr">#></span> k1 0.044946770</span> +<span class="r-out co"><span class="r-pr">#></span> k2 0.002868336</span> +<span class="r-out co"><span class="r-pr">#></span> g 0.526942415</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 2.221302196</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"><span class="fu">parms</span><span class="op">(</span><span class="va">fits</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> $SFO</span> +<span class="r-out co"><span class="r-pr">#></span> Dataset 6 Dataset 7 Dataset 8 Dataset 9 Dataset 10</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 88.52275400 82.666781678 86.8547308 91.7779306 82.14809450</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.05794659 0.009647805 0.2102974 0.1232258 0.00720421</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 5.15274487 7.040168584 3.6769645 6.4669234 6.50457673</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $FOMC</span> +<span class="r-out co"><span class="r-pr">#></span> Dataset 6 Dataset 7 Dataset 8 Dataset 9 Dataset 10</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 95.558575 92.6837649 90.719787 98.383939 94.8481459</span> +<span class="r-out co"><span class="r-pr">#></span> alpha 1.338667 0.4967832 1.639099 1.074460 0.2805272</span> +<span class="r-out co"><span class="r-pr">#></span> beta 13.033315 14.1451255 5.007077 4.397126 6.9052224</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 1.847671 1.9167519 1.066063 3.146056 1.6222778</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $DFOP</span> +<span class="r-out co"><span class="r-pr">#></span> Dataset 6 Dataset 7 Dataset 8 Dataset 9 Dataset 10</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 96.55213663 91.058971589 90.34509493 98.14858820 94.311323734</span> +<span class="r-out co"><span class="r-pr">#></span> k1 0.21954588 0.044946770 0.41232288 0.31697588 0.080663857</span> +<span class="r-out co"><span class="r-pr">#></span> k2 0.02957934 0.002868336 0.07581766 0.03260384 0.003425417</span> +<span class="r-out co"><span class="r-pr">#></span> g 0.44845068 0.526942415 0.66091967 0.65322767 0.342652880</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 1.35690468 2.221302196 1.34169076 2.87159846 1.942067831</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"><span class="fu">parms</span><span class="op">(</span><span class="va">fits</span>, transformed <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> $SFO</span> +<span class="r-out co"><span class="r-pr">#></span> Dataset 6 Dataset 7 Dataset 8 Dataset 9 Dataset 10</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 88.522754 82.666782 86.854731 91.777931 82.148094</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent -2.848234 -4.641025 -1.559232 -2.093737 -4.933090</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 5.152745 7.040169 3.676964 6.466923 6.504577</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $FOMC</span> +<span class="r-out co"><span class="r-pr">#></span> Dataset 6 Dataset 7 Dataset 8 Dataset 9 Dataset 10</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 95.5585751 92.6837649 90.7197870 98.38393897 94.848146</span> +<span class="r-out co"><span class="r-pr">#></span> log_alpha 0.2916741 -0.6996015 0.4941466 0.07181816 -1.271085</span> +<span class="r-out co"><span class="r-pr">#></span> log_beta 2.5675088 2.6493701 1.6108523 1.48095106 1.932278</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 1.8476712 1.9167519 1.0660627 3.14605557 1.622278</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $DFOP</span> +<span class="r-out co"><span class="r-pr">#></span> Dataset 6 Dataset 7 Dataset 8 Dataset 9 Dataset 10</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 96.5521366 91.0589716 90.3450949 98.1485882 94.3113237</span> +<span class="r-out co"><span class="r-pr">#></span> log_k1 -1.5161940 -3.1022764 -0.8859486 -1.1489296 -2.5174647</span> +<span class="r-out co"><span class="r-pr">#></span> log_k2 -3.5206791 -5.8540232 -2.5794240 -3.4233253 -5.6765322</span> +<span class="r-out co"><span class="r-pr">#></span> g_qlogis -0.2069326 0.1078741 0.6673953 0.6332573 -0.6514943</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 1.3569047 2.2213022 1.3416908 2.8715985 1.9420678</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/plot.mixed.mmkin-1.png b/docs/reference/plot.mixed.mmkin-1.png Binary files differindex be3c664a..8a09a167 100644 --- a/docs/reference/plot.mixed.mmkin-1.png +++ b/docs/reference/plot.mixed.mmkin-1.png diff --git a/docs/reference/plot.mixed.mmkin-2.png b/docs/reference/plot.mixed.mmkin-2.png Binary files differindex 933d477b..67c9b8ab 100644 --- a/docs/reference/plot.mixed.mmkin-2.png +++ b/docs/reference/plot.mixed.mmkin-2.png diff --git a/docs/reference/plot.mixed.mmkin.html b/docs/reference/plot.mixed.mmkin.html index 090a644c..da382eb9 100644 --- a/docs/reference/plot.mixed.mmkin.html +++ b/docs/reference/plot.mixed.mmkin.html @@ -1,67 +1,12 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Plot predictions from a fitted nonlinear mixed model obtained via an mmkin row object — plot.mixed.mmkin • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Plot predictions from a fitted nonlinear mixed model obtained via an mmkin row object — plot.mixed.mmkin" /> -<meta property="og:description" content="Plot predictions from a fitted nonlinear mixed model obtained via an mmkin row object" /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Plot predictions from a fitted nonlinear mixed model obtained via an mmkin row object — plot.mixed.mmkin • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Plot predictions from a fitted nonlinear mixed model obtained via an mmkin row object — plot.mixed.mmkin"><meta property="og:description" content="Plot predictions from a fitted nonlinear mixed model obtained via an mmkin row object"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -72,13 +17,12 @@ </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.5</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -87,8 +31,7 @@ <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -98,6 +41,9 @@ <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -112,34 +58,27 @@ <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Plot predictions from a fitted nonlinear mixed model obtained via an mmkin row object</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/plot.mixed.mmkin.R'><code>R/plot.mixed.mmkin.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/plot.mixed.mmkin.R" class="external-link"><code>R/plot.mixed.mmkin.R</code></a></small> <div class="hidden name"><code>plot.mixed.mmkin.Rd</code></div> </div> @@ -147,167 +86,158 @@ <p>Plot predictions from a fitted nonlinear mixed model obtained via an mmkin row object</p> </div> - <pre class="usage"><span class='co'># S3 method for mixed.mmkin</span> -<span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span> - <span class='va'>x</span>, - i <span class='op'>=</span> <span class='fl'>1</span><span class='op'>:</span><span class='fu'><a href='https://rdrr.io/r/base/nrow.html'>ncol</a></span><span class='op'>(</span><span class='va'>x</span><span class='op'>$</span><span class='va'>mmkin</span><span class='op'>)</span>, - obs_vars <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/names.html'>names</a></span><span class='op'>(</span><span class='va'>x</span><span class='op'>$</span><span class='va'>mkinmod</span><span class='op'>$</span><span class='va'>map</span><span class='op'>)</span>, - standardized <span class='op'>=</span> <span class='cn'>TRUE</span>, - xlab <span class='op'>=</span> <span class='st'>"Time"</span>, - xlim <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/range.html'>range</a></span><span class='op'>(</span><span class='va'>x</span><span class='op'>$</span><span class='va'>data</span><span class='op'>$</span><span class='va'>time</span><span class='op'>)</span>, - resplot <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"predicted"</span>, <span class='st'>"time"</span><span class='op'>)</span>, - pred_over <span class='op'>=</span> <span class='cn'>NULL</span>, - ymax <span class='op'>=</span> <span class='st'>"auto"</span>, - maxabs <span class='op'>=</span> <span class='st'>"auto"</span>, - ncol.legend <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/ifelse.html'>ifelse</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/length.html'>length</a></span><span class='op'>(</span><span class='va'>i</span><span class='op'>)</span> <span class='op'><=</span> <span class='fl'>3</span>, <span class='fu'><a href='https://rdrr.io/r/base/length.html'>length</a></span><span class='op'>(</span><span class='va'>i</span><span class='op'>)</span> <span class='op'>+</span> <span class='fl'>1</span>, <span class='fu'><a href='https://rdrr.io/r/base/ifelse.html'>ifelse</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/length.html'>length</a></span><span class='op'>(</span><span class='va'>i</span><span class='op'>)</span> <span class='op'><=</span> <span class='fl'>8</span>, <span class='fl'>3</span>, <span class='fl'>4</span><span class='op'>)</span><span class='op'>)</span>, - nrow.legend <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/Round.html'>ceiling</a></span><span class='op'>(</span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/length.html'>length</a></span><span class='op'>(</span><span class='va'>i</span><span class='op'>)</span> <span class='op'>+</span> <span class='fl'>1</span><span class='op'>)</span><span class='op'>/</span><span class='va'>ncol.legend</span><span class='op'>)</span>, - rel.height.legend <span class='op'>=</span> <span class='fl'>0.02</span> <span class='op'>+</span> <span class='fl'>0.07</span> <span class='op'>*</span> <span class='va'>nrow.legend</span>, - rel.height.bottom <span class='op'>=</span> <span class='fl'>1.1</span>, - pch_ds <span class='op'>=</span> <span class='fl'>1</span><span class='op'>:</span><span class='fu'><a href='https://rdrr.io/r/base/length.html'>length</a></span><span class='op'>(</span><span class='va'>i</span><span class='op'>)</span>, - col_ds <span class='op'>=</span> <span class='va'>pch_ds</span> <span class='op'>+</span> <span class='fl'>1</span>, - lty_ds <span class='op'>=</span> <span class='va'>col_ds</span>, - frame <span class='op'>=</span> <span class='cn'>TRUE</span>, - <span class='va'>...</span> -<span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for mixed.mmkin</span> +<span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span> + <span class="va">x</span>, + i <span class="op">=</span> <span class="fl">1</span><span class="op">:</span><span class="fu"><a href="https://rdrr.io/r/base/nrow.html" class="external-link">ncol</a></span><span class="op">(</span><span class="va">x</span><span class="op">$</span><span class="va">mmkin</span><span class="op">)</span>, + obs_vars <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">x</span><span class="op">$</span><span class="va">mkinmod</span><span class="op">$</span><span class="va">map</span><span class="op">)</span>, + standardized <span class="op">=</span> <span class="cn">TRUE</span>, + xlab <span class="op">=</span> <span class="st">"Time"</span>, + xlim <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/range.html" class="external-link">range</a></span><span class="op">(</span><span class="va">x</span><span class="op">$</span><span class="va">data</span><span class="op">$</span><span class="va">time</span><span class="op">)</span>, + resplot <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"predicted"</span>, <span class="st">"time"</span><span class="op">)</span>, + pred_over <span class="op">=</span> <span class="cn">NULL</span>, + test_log_parms <span class="op">=</span> <span class="cn">FALSE</span>, + conf.level <span class="op">=</span> <span class="fl">0.6</span>, + ymax <span class="op">=</span> <span class="st">"auto"</span>, + maxabs <span class="op">=</span> <span class="st">"auto"</span>, + ncol.legend <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/ifelse.html" class="external-link">ifelse</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/length.html" class="external-link">length</a></span><span class="op">(</span><span class="va">i</span><span class="op">)</span> <span class="op"><=</span> <span class="fl">3</span>, <span class="fu"><a href="https://rdrr.io/r/base/length.html" class="external-link">length</a></span><span class="op">(</span><span class="va">i</span><span class="op">)</span> <span class="op">+</span> <span class="fl">1</span>, <span class="fu"><a href="https://rdrr.io/r/base/ifelse.html" class="external-link">ifelse</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/length.html" class="external-link">length</a></span><span class="op">(</span><span class="va">i</span><span class="op">)</span> <span class="op"><=</span> <span class="fl">8</span>, <span class="fl">3</span>, <span class="fl">4</span><span class="op">)</span><span class="op">)</span>, + nrow.legend <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/Round.html" class="external-link">ceiling</a></span><span class="op">(</span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/length.html" class="external-link">length</a></span><span class="op">(</span><span class="va">i</span><span class="op">)</span> <span class="op">+</span> <span class="fl">1</span><span class="op">)</span><span class="op">/</span><span class="va">ncol.legend</span><span class="op">)</span>, + rel.height.legend <span class="op">=</span> <span class="fl">0.02</span> <span class="op">+</span> <span class="fl">0.07</span> <span class="op">*</span> <span class="va">nrow.legend</span>, + rel.height.bottom <span class="op">=</span> <span class="fl">1.1</span>, + pch_ds <span class="op">=</span> <span class="fl">1</span><span class="op">:</span><span class="fu"><a href="https://rdrr.io/r/base/length.html" class="external-link">length</a></span><span class="op">(</span><span class="va">i</span><span class="op">)</span>, + col_ds <span class="op">=</span> <span class="va">pch_ds</span> <span class="op">+</span> <span class="fl">1</span>, + lty_ds <span class="op">=</span> <span class="va">col_ds</span>, + frame <span class="op">=</span> <span class="cn">TRUE</span>, + <span class="va">...</span> +<span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>x</th> - <td><p>An object of class <a href='mixed.html'>mixed.mmkin</a>, <a href='nlme.mmkin.html'>nlme.mmkin</a></p></td> - </tr> - <tr> - <th>i</th> - <td><p>A numeric index to select datasets for which to plot the individual predictions, -in case plots get too large</p></td> - </tr> - <tr> - <th>obs_vars</th> - <td><p>A character vector of names of the observed variables for + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>x</dt> +<dd><p>An object of class <a href="mixed.html">mixed.mmkin</a>, <a href="saem.html">saem.mmkin</a> or <a href="nlme.mmkin.html">nlme.mmkin</a></p></dd> +<dt>i</dt> +<dd><p>A numeric index to select datasets for which to plot the individual predictions, +in case plots get too large</p></dd> +<dt>obs_vars</dt> +<dd><p>A character vector of names of the observed variables for which the data and the model should be plotted. Defauls to all observed -variables in the model.</p></td> - </tr> - <tr> - <th>standardized</th> - <td><p>Should the residuals be standardized? Only takes effect if -<code>resplot = "time"</code>.</p></td> - </tr> - <tr> - <th>xlab</th> - <td><p>Label for the x axis.</p></td> - </tr> - <tr> - <th>xlim</th> - <td><p>Plot range in x direction.</p></td> - </tr> - <tr> - <th>resplot</th> - <td><p>Should the residuals plotted against time or against -predicted values?</p></td> - </tr> - <tr> - <th>pred_over</th> - <td><p>Named list of alternative predictions as obtained -from <a href='mkinpredict.html'>mkinpredict</a> with a compatible <a href='mkinmod.html'>mkinmod</a>.</p></td> - </tr> - <tr> - <th>ymax</th> - <td><p>Vector of maximum y axis values</p></td> - </tr> - <tr> - <th>maxabs</th> - <td><p>Maximum absolute value of the residuals. This is used for the -scaling of the y axis and defaults to "auto".</p></td> - </tr> - <tr> - <th>ncol.legend</th> - <td><p>Number of columns to use in the legend</p></td> - </tr> - <tr> - <th>nrow.legend</th> - <td><p>Number of rows to use in the legend</p></td> - </tr> - <tr> - <th>rel.height.legend</th> - <td><p>The relative height of the legend shown on top</p></td> - </tr> - <tr> - <th>rel.height.bottom</th> - <td><p>The relative height of the bottom plot row</p></td> - </tr> - <tr> - <th>pch_ds</th> - <td><p>Symbols to be used for plotting the data.</p></td> - </tr> - <tr> - <th>col_ds</th> - <td><p>Colors used for plotting the observed data and the -corresponding model prediction lines for the different datasets.</p></td> - </tr> - <tr> - <th>lty_ds</th> - <td><p>Line types to be used for the model predictions.</p></td> - </tr> - <tr> - <th>frame</th> - <td><p>Should a frame be drawn around the plots?</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Further arguments passed to <code><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></code>.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - +variables in the model.</p></dd> +<dt>standardized</dt> +<dd><p>Should the residuals be standardized? Only takes effect if +<code>resplot = "time"</code>.</p></dd> +<dt>xlab</dt> +<dd><p>Label for the x axis.</p></dd> +<dt>xlim</dt> +<dd><p>Plot range in x direction.</p></dd> +<dt>resplot</dt> +<dd><p>Should the residuals plotted against time or against +predicted values?</p></dd> +<dt>pred_over</dt> +<dd><p>Named list of alternative predictions as obtained +from <a href="mkinpredict.html">mkinpredict</a> with a compatible <a href="mkinmod.html">mkinmod</a>.</p></dd> +<dt>test_log_parms</dt> +<dd><p>Passed to <a href="mean_degparms.html">mean_degparms</a> in the case of an +<a href="mixed.html">mixed.mmkin</a> object</p></dd> +<dt>conf.level</dt> +<dd><p>Passed to <a href="mean_degparms.html">mean_degparms</a> in the case of an +<a href="mixed.html">mixed.mmkin</a> object</p></dd> +<dt>ymax</dt> +<dd><p>Vector of maximum y axis values</p></dd> +<dt>maxabs</dt> +<dd><p>Maximum absolute value of the residuals. This is used for the +scaling of the y axis and defaults to "auto".</p></dd> +<dt>ncol.legend</dt> +<dd><p>Number of columns to use in the legend</p></dd> +<dt>nrow.legend</dt> +<dd><p>Number of rows to use in the legend</p></dd> +<dt>rel.height.legend</dt> +<dd><p>The relative height of the legend shown on top</p></dd> +<dt>rel.height.bottom</dt> +<dd><p>The relative height of the bottom plot row</p></dd> +<dt>pch_ds</dt> +<dd><p>Symbols to be used for plotting the data.</p></dd> +<dt>col_ds</dt> +<dd><p>Colors used for plotting the observed data and the +corresponding model prediction lines for the different datasets.</p></dd> +<dt>lty_ds</dt> +<dd><p>Line types to be used for the model predictions.</p></dd> +<dt>frame</dt> +<dd><p>Should a frame be drawn around the plots?</p></dd> +<dt>...</dt> +<dd><p>Further arguments passed to <code><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></code>.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The function is called for its side effect.</p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='va'>ds</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/lapply.html'>lapply</a></span><span class='op'>(</span><span class='va'>experimental_data_for_UBA_2019</span><span class='op'>[</span><span class='fl'>6</span><span class='op'>:</span><span class='fl'>10</span><span class='op'>]</span>, - <span class='kw'>function</span><span class='op'>(</span><span class='va'>x</span><span class='op'>)</span> <span class='va'>x</span><span class='op'>$</span><span class='va'>data</span><span class='op'>[</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"name"</span>, <span class='st'>"time"</span>, <span class='st'>"value"</span><span class='op'>)</span><span class='op'>]</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/names.html'>names</a></span><span class='op'>(</span><span class='va'>ds</span><span class='op'>)</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/paste.html'>paste0</a></span><span class='op'>(</span><span class='st'>"ds "</span>, <span class='fl'>6</span><span class='op'>:</span><span class='fl'>10</span><span class='op'>)</span> -<span class='va'>dfop_sfo</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"DFOP"</span>, <span class='st'>"A1"</span><span class='op'>)</span>, - A1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='co'># \dontrun{</span> -<span class='va'>f</span> <span class='op'><-</span> <span class='fu'><a href='mmkin.html'>mmkin</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span><span class='st'>"DFOP-SFO"</span> <span class='op'>=</span> <span class='va'>dfop_sfo</span><span class='op'>)</span>, <span class='va'>ds</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>f</span><span class='op'>[</span>, <span class='fl'>3</span><span class='op'>:</span><span class='fl'>4</span><span class='op'>]</span>, standardized <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='img'><img src='plot.mixed.mmkin-1.png' alt='' width='700' height='433' /></div><div class='input'> -<span class='co'># For this fit we need to increase pnlsMaxiter, and we increase the</span> -<span class='co'># tolerance in order to speed up the fit for this example evaluation</span> -<span class='va'>f_nlme</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme</a></span><span class='op'>(</span><span class='va'>f</span>, control <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>pnlsMaxIter <span class='op'>=</span> <span class='fl'>120</span>, tolerance <span class='op'>=</span> <span class='fl'>1e-3</span><span class='op'>)</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>f_nlme</span><span class='op'>)</span> -</div><div class='img'><img src='plot.mixed.mmkin-2.png' alt='' width='700' height='433' /></div><div class='input'> -<span class='co'># }</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="va">ds</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="va">experimental_data_for_UBA_2019</span><span class="op">[</span><span class="fl">6</span><span class="op">:</span><span class="fl">10</span><span class="op">]</span>,</span> +<span class="r-in"> <span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="va">x</span><span class="op">$</span><span class="va">data</span><span class="op">[</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"name"</span>, <span class="st">"time"</span>, <span class="st">"value"</span><span class="op">)</span><span class="op">]</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">ds</span><span class="op">)</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste0</a></span><span class="op">(</span><span class="st">"ds "</span>, <span class="fl">6</span><span class="op">:</span><span class="fl">10</span><span class="op">)</span></span> +<span class="r-in"><span class="va">dfop_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="st">"A1"</span><span class="op">)</span>,</span> +<span class="r-in"> A1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="va">f</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="st">"DFOP-SFO"</span> <span class="op">=</span> <span class="va">dfop_sfo</span><span class="op">)</span>, <span class="va">ds</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f</span><span class="op">[</span>, <span class="fl">3</span><span class="op">:</span><span class="fl">4</span><span class="op">]</span>, standardized <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-plt img"><img src="plot.mixed.mmkin-1.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># For this fit we need to increase pnlsMaxiter, and we increase the</span></span> +<span class="r-in"><span class="co"># tolerance in order to speed up the fit for this example evaluation</span></span> +<span class="r-in"><span class="co"># It still takes 20 seconds to run</span></span> +<span class="r-in"><span class="va">f_nlme</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></span><span class="op">(</span><span class="va">f</span>, control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>pnlsMaxIter <span class="op">=</span> <span class="fl">120</span>, tolerance <span class="op">=</span> <span class="fl">1e-3</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_nlme</span><span class="op">)</span></span> +<span class="r-plt img"><img src="plot.mixed.mmkin-2.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">f_saem</span> <span class="op"><-</span> <span class="fu"><a href="saem.html">saem</a></span><span class="op">(</span><span class="va">f</span>, transformations <span class="op">=</span> <span class="st">"saemix"</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in saem(f, transformations = "saemix"):</span> unused argument (transformations = "saemix")</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_saem</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in plot(f_saem):</span> object 'f_saem' not found</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">f_obs</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="st">"DFOP-SFO"</span> <span class="op">=</span> <span class="va">dfop_sfo</span><span class="op">)</span>, <span class="va">ds</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"obs"</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_nlmix</span> <span class="op"><-</span> <span class="fu">nlmix</span><span class="op">(</span><span class="va">f_obs</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in nlmix(f_obs):</span> could not find function "nlmix"</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_nlmix</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in plot(f_nlmix):</span> object 'f_nlmix' not found</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># We can overlay the two variants if we generate predictions</span></span> +<span class="r-in"><span class="va">pred_nlme</span> <span class="op"><-</span> <span class="fu"><a href="mkinpredict.html">mkinpredict</a></span><span class="op">(</span><span class="va">dfop_sfo</span>,</span> +<span class="r-in"> <span class="va">f_nlme</span><span class="op">$</span><span class="va">bparms.optim</span><span class="op">[</span><span class="op">-</span><span class="fl">1</span><span class="op">]</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="va">f_nlme</span><span class="op">$</span><span class="va">bparms.optim</span><span class="op">[[</span><span class="fl">1</span><span class="op">]</span><span class="op">]</span>, A1 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/seq.html" class="external-link">seq</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">180</span>, by <span class="op">=</span> <span class="fl">0.2</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_saem</span>, pred_over <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>nlme <span class="op">=</span> <span class="va">pred_nlme</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in plot(f_saem, pred_over = list(nlme = pred_nlme)):</span> object 'f_saem' not found</span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/plot.mkinfit-1.png b/docs/reference/plot.mkinfit-1.png Binary files differindex 54e5c46f..ea1032fb 100644 --- a/docs/reference/plot.mkinfit-1.png +++ b/docs/reference/plot.mkinfit-1.png diff --git a/docs/reference/plot.mkinfit-2.png b/docs/reference/plot.mkinfit-2.png Binary files differindex ff8418a3..cef94cb8 100644 --- a/docs/reference/plot.mkinfit-2.png +++ b/docs/reference/plot.mkinfit-2.png diff --git a/docs/reference/plot.mkinfit-3.png b/docs/reference/plot.mkinfit-3.png Binary files differindex 54f2b981..8a9dbd13 100644 --- a/docs/reference/plot.mkinfit-3.png +++ b/docs/reference/plot.mkinfit-3.png diff --git a/docs/reference/plot.mkinfit-4.png b/docs/reference/plot.mkinfit-4.png Binary files differindex 7a7bfc6c..a7164caa 100644 --- a/docs/reference/plot.mkinfit-4.png +++ b/docs/reference/plot.mkinfit-4.png diff --git a/docs/reference/plot.mkinfit-5.png b/docs/reference/plot.mkinfit-5.png Binary files differindex 6a6741e7..f90b3f54 100644 --- a/docs/reference/plot.mkinfit-5.png +++ b/docs/reference/plot.mkinfit-5.png diff --git a/docs/reference/plot.mkinfit-6.png b/docs/reference/plot.mkinfit-6.png Binary files differindex c4d0b9c7..3d0fb25e 100644 --- a/docs/reference/plot.mkinfit-6.png +++ b/docs/reference/plot.mkinfit-6.png diff --git a/docs/reference/plot.mkinfit-7.png b/docs/reference/plot.mkinfit-7.png Binary files differindex 802b00ef..3e5d828e 100644 --- a/docs/reference/plot.mkinfit-7.png +++ b/docs/reference/plot.mkinfit-7.png diff --git a/docs/reference/plot.mkinfit.html b/docs/reference/plot.mkinfit.html index ff6da93e..0ad6ffc0 100644 --- a/docs/reference/plot.mkinfit.html +++ b/docs/reference/plot.mkinfit.html @@ -1,69 +1,14 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Plot the observed data and the fitted model of an mkinfit object — plot.mkinfit • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Plot the observed data and the fitted model of an mkinfit object — plot.mkinfit" /> -<meta property="og:description" content="Solves the differential equations with the optimised and fixed parameters +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Plot the observed data and the fitted model of an mkinfit object — plot.mkinfit • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Plot the observed data and the fitted model of an mkinfit object — plot.mkinfit"><meta property="og:description" content="Solves the differential equations with the optimised and fixed parameters from a previous successful call to mkinfit and plots the -observed data together with the solution of the fitted model." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +observed data together with the solution of the fitted model."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -74,13 +19,12 @@ observed data together with the solution of the fitted model." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -89,8 +33,7 @@ observed data together with the solution of the fitted model." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -100,6 +43,9 @@ observed data together with the solution of the fitted model." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -114,279 +60,231 @@ observed data together with the solution of the fitted model." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Plot the observed data and the fitted model of an mkinfit object</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/plot.mkinfit.R'><code>R/plot.mkinfit.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/plot.mkinfit.R" class="external-link"><code>R/plot.mkinfit.R</code></a></small> <div class="hidden name"><code>plot.mkinfit.Rd</code></div> </div> <div class="ref-description"> <p>Solves the differential equations with the optimised and fixed parameters -from a previous successful call to <code><a href='mkinfit.html'>mkinfit</a></code> and plots the +from a previous successful call to <code><a href="mkinfit.html">mkinfit</a></code> and plots the observed data together with the solution of the fitted model.</p> </div> - <pre class="usage"><span class='co'># S3 method for mkinfit</span> -<span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span> - <span class='va'>x</span>, - fit <span class='op'>=</span> <span class='va'>x</span>, - obs_vars <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/names.html'>names</a></span><span class='op'>(</span><span class='va'>fit</span><span class='op'>$</span><span class='va'>mkinmod</span><span class='op'>$</span><span class='va'>map</span><span class='op'>)</span>, - xlab <span class='op'>=</span> <span class='st'>"Time"</span>, - ylab <span class='op'>=</span> <span class='st'>"Residue"</span>, - xlim <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/range.html'>range</a></span><span class='op'>(</span><span class='va'>fit</span><span class='op'>$</span><span class='va'>data</span><span class='op'>$</span><span class='va'>time</span><span class='op'>)</span>, - ylim <span class='op'>=</span> <span class='st'>"default"</span>, - col_obs <span class='op'>=</span> <span class='fl'>1</span><span class='op'>:</span><span class='fu'><a href='https://rdrr.io/r/base/length.html'>length</a></span><span class='op'>(</span><span class='va'>obs_vars</span><span class='op'>)</span>, - pch_obs <span class='op'>=</span> <span class='va'>col_obs</span>, - lty_obs <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/rep.html'>rep</a></span><span class='op'>(</span><span class='fl'>1</span>, <span class='fu'><a href='https://rdrr.io/r/base/length.html'>length</a></span><span class='op'>(</span><span class='va'>obs_vars</span><span class='op'>)</span><span class='op'>)</span>, - add <span class='op'>=</span> <span class='cn'>FALSE</span>, - legend <span class='op'>=</span> <span class='op'>!</span><span class='va'>add</span>, - show_residuals <span class='op'>=</span> <span class='cn'>FALSE</span>, - show_errplot <span class='op'>=</span> <span class='cn'>FALSE</span>, - maxabs <span class='op'>=</span> <span class='st'>"auto"</span>, - sep_obs <span class='op'>=</span> <span class='cn'>FALSE</span>, - rel.height.middle <span class='op'>=</span> <span class='fl'>0.9</span>, - row_layout <span class='op'>=</span> <span class='cn'>FALSE</span>, - lpos <span class='op'>=</span> <span class='st'>"topright"</span>, - inset <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0.05</span>, <span class='fl'>0.05</span><span class='op'>)</span>, - show_errmin <span class='op'>=</span> <span class='cn'>FALSE</span>, - errmin_digits <span class='op'>=</span> <span class='fl'>3</span>, - frame <span class='op'>=</span> <span class='cn'>TRUE</span>, - <span class='va'>...</span> -<span class='op'>)</span> - -<span class='fu'>plot_sep</span><span class='op'>(</span> - <span class='va'>fit</span>, - show_errmin <span class='op'>=</span> <span class='cn'>TRUE</span>, - show_residuals <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/ifelse.html'>ifelse</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/identical.html'>identical</a></span><span class='op'>(</span><span class='va'>fit</span><span class='op'>$</span><span class='va'>err_mod</span>, <span class='st'>"const"</span><span class='op'>)</span>, <span class='cn'>TRUE</span>, <span class='st'>"standardized"</span><span class='op'>)</span>, - <span class='va'>...</span> -<span class='op'>)</span> - -<span class='fu'>plot_res</span><span class='op'>(</span> - <span class='va'>fit</span>, - sep_obs <span class='op'>=</span> <span class='cn'>FALSE</span>, - show_errmin <span class='op'>=</span> <span class='va'>sep_obs</span>, - standardized <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/ifelse.html'>ifelse</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/identical.html'>identical</a></span><span class='op'>(</span><span class='va'>fit</span><span class='op'>$</span><span class='va'>err_mod</span>, <span class='st'>"const"</span><span class='op'>)</span>, <span class='cn'>FALSE</span>, <span class='cn'>TRUE</span><span class='op'>)</span>, - <span class='va'>...</span> -<span class='op'>)</span> - -<span class='fu'>plot_err</span><span class='op'>(</span><span class='va'>fit</span>, sep_obs <span class='op'>=</span> <span class='cn'>FALSE</span>, show_errmin <span class='op'>=</span> <span class='va'>sep_obs</span>, <span class='va'>...</span><span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for mkinfit</span> +<span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span> + <span class="va">x</span>, + fit <span class="op">=</span> <span class="va">x</span>, + obs_vars <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">fit</span><span class="op">$</span><span class="va">mkinmod</span><span class="op">$</span><span class="va">map</span><span class="op">)</span>, + xlab <span class="op">=</span> <span class="st">"Time"</span>, + ylab <span class="op">=</span> <span class="st">"Residue"</span>, + xlim <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/range.html" class="external-link">range</a></span><span class="op">(</span><span class="va">fit</span><span class="op">$</span><span class="va">data</span><span class="op">$</span><span class="va">time</span><span class="op">)</span>, + ylim <span class="op">=</span> <span class="st">"default"</span>, + col_obs <span class="op">=</span> <span class="fl">1</span><span class="op">:</span><span class="fu"><a href="https://rdrr.io/r/base/length.html" class="external-link">length</a></span><span class="op">(</span><span class="va">obs_vars</span><span class="op">)</span>, + pch_obs <span class="op">=</span> <span class="va">col_obs</span>, + lty_obs <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/rep.html" class="external-link">rep</a></span><span class="op">(</span><span class="fl">1</span>, <span class="fu"><a href="https://rdrr.io/r/base/length.html" class="external-link">length</a></span><span class="op">(</span><span class="va">obs_vars</span><span class="op">)</span><span class="op">)</span>, + add <span class="op">=</span> <span class="cn">FALSE</span>, + legend <span class="op">=</span> <span class="op">!</span><span class="va">add</span>, + show_residuals <span class="op">=</span> <span class="cn">FALSE</span>, + show_errplot <span class="op">=</span> <span class="cn">FALSE</span>, + maxabs <span class="op">=</span> <span class="st">"auto"</span>, + sep_obs <span class="op">=</span> <span class="cn">FALSE</span>, + rel.height.middle <span class="op">=</span> <span class="fl">0.9</span>, + row_layout <span class="op">=</span> <span class="cn">FALSE</span>, + lpos <span class="op">=</span> <span class="st">"topright"</span>, + inset <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0.05</span>, <span class="fl">0.05</span><span class="op">)</span>, + show_errmin <span class="op">=</span> <span class="cn">FALSE</span>, + errmin_digits <span class="op">=</span> <span class="fl">3</span>, + frame <span class="op">=</span> <span class="cn">TRUE</span>, + <span class="va">...</span> +<span class="op">)</span> + +<span class="fu">plot_sep</span><span class="op">(</span> + <span class="va">fit</span>, + show_errmin <span class="op">=</span> <span class="cn">TRUE</span>, + show_residuals <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/ifelse.html" class="external-link">ifelse</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/identical.html" class="external-link">identical</a></span><span class="op">(</span><span class="va">fit</span><span class="op">$</span><span class="va">err_mod</span>, <span class="st">"const"</span><span class="op">)</span>, <span class="cn">TRUE</span>, <span class="st">"standardized"</span><span class="op">)</span>, + <span class="va">...</span> +<span class="op">)</span> + +<span class="fu">plot_res</span><span class="op">(</span> + <span class="va">fit</span>, + sep_obs <span class="op">=</span> <span class="cn">FALSE</span>, + show_errmin <span class="op">=</span> <span class="va">sep_obs</span>, + standardized <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/ifelse.html" class="external-link">ifelse</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/identical.html" class="external-link">identical</a></span><span class="op">(</span><span class="va">fit</span><span class="op">$</span><span class="va">err_mod</span>, <span class="st">"const"</span><span class="op">)</span>, <span class="cn">FALSE</span>, <span class="cn">TRUE</span><span class="op">)</span>, + <span class="va">...</span> +<span class="op">)</span> + +<span class="fu">plot_err</span><span class="op">(</span><span class="va">fit</span>, sep_obs <span class="op">=</span> <span class="cn">FALSE</span>, show_errmin <span class="op">=</span> <span class="va">sep_obs</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>x</th> - <td><p>Alias for fit introduced for compatibility with the generic S3 -method.</p></td> - </tr> - <tr> - <th>fit</th> - <td><p>An object of class <code><a href='mkinfit.html'>mkinfit</a></code>.</p></td> - </tr> - <tr> - <th>obs_vars</th> - <td><p>A character vector of names of the observed variables for + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>x</dt> +<dd><p>Alias for fit introduced for compatibility with the generic S3 +method.</p></dd> +<dt>fit</dt> +<dd><p>An object of class <code><a href="mkinfit.html">mkinfit</a></code>.</p></dd> +<dt>obs_vars</dt> +<dd><p>A character vector of names of the observed variables for which the data and the model should be plotted. Defauls to all observed -variables in the model.</p></td> - </tr> - <tr> - <th>xlab</th> - <td><p>Label for the x axis.</p></td> - </tr> - <tr> - <th>ylab</th> - <td><p>Label for the y axis.</p></td> - </tr> - <tr> - <th>xlim</th> - <td><p>Plot range in x direction.</p></td> - </tr> - <tr> - <th>ylim</th> - <td><p>Plot range in y direction.</p></td> - </tr> - <tr> - <th>col_obs</th> - <td><p>Colors used for plotting the observed data and the -corresponding model prediction lines.</p></td> - </tr> - <tr> - <th>pch_obs</th> - <td><p>Symbols to be used for plotting the data.</p></td> - </tr> - <tr> - <th>lty_obs</th> - <td><p>Line types to be used for the model predictions.</p></td> - </tr> - <tr> - <th>add</th> - <td><p>Should the plot be added to an existing plot?</p></td> - </tr> - <tr> - <th>legend</th> - <td><p>Should a legend be added to the plot?</p></td> - </tr> - <tr> - <th>show_residuals</th> - <td><p>Should residuals be shown? If only one plot of the +variables in the model.</p></dd> +<dt>xlab</dt> +<dd><p>Label for the x axis.</p></dd> +<dt>ylab</dt> +<dd><p>Label for the y axis.</p></dd> +<dt>xlim</dt> +<dd><p>Plot range in x direction.</p></dd> +<dt>ylim</dt> +<dd><p>Plot range in y direction.</p></dd> +<dt>col_obs</dt> +<dd><p>Colors used for plotting the observed data and the +corresponding model prediction lines.</p></dd> +<dt>pch_obs</dt> +<dd><p>Symbols to be used for plotting the data.</p></dd> +<dt>lty_obs</dt> +<dd><p>Line types to be used for the model predictions.</p></dd> +<dt>add</dt> +<dd><p>Should the plot be added to an existing plot?</p></dd> +<dt>legend</dt> +<dd><p>Should a legend be added to the plot?</p></dd> +<dt>show_residuals</dt> +<dd><p>Should residuals be shown? If only one plot of the fits is shown, the residual plot is in the lower third of the plot. Otherwise, i.e. if "sep_obs" is given, the residual plots will be located to the right of the plots of the fitted curves. If this is set to 'standardized', a plot of the residuals divided by the standard deviation -given by the fitted error model will be shown.</p></td> - </tr> - <tr> - <th>show_errplot</th> - <td><p>Should squared residuals and the error model be shown? +given by the fitted error model will be shown.</p></dd> +<dt>show_errplot</dt> +<dd><p>Should squared residuals and the error model be shown? If only one plot of the fits is shown, this plot is in the lower third of the plot. Otherwise, i.e. if "sep_obs" is given, the residual plots will -be located to the right of the plots of the fitted curves.</p></td> - </tr> - <tr> - <th>maxabs</th> - <td><p>Maximum absolute value of the residuals. This is used for the -scaling of the y axis and defaults to "auto".</p></td> - </tr> - <tr> - <th>sep_obs</th> - <td><p>Should the observed variables be shown in separate subplots? +be located to the right of the plots of the fitted curves.</p></dd> +<dt>maxabs</dt> +<dd><p>Maximum absolute value of the residuals. This is used for the +scaling of the y axis and defaults to "auto".</p></dd> +<dt>sep_obs</dt> +<dd><p>Should the observed variables be shown in separate subplots? If yes, residual plots requested by "show_residuals" will be shown next -to, not below the plot of the fits.</p></td> - </tr> - <tr> - <th>rel.height.middle</th> - <td><p>The relative height of the middle plot, if more -than two rows of plots are shown.</p></td> - </tr> - <tr> - <th>row_layout</th> - <td><p>Should we use a row layout where the residual plot or the -error model plot is shown to the right?</p></td> - </tr> - <tr> - <th>lpos</th> - <td><p>Position(s) of the legend(s). Passed to <code><a href='https://rdrr.io/r/graphics/legend.html'>legend</a></code> as +to, not below the plot of the fits.</p></dd> +<dt>rel.height.middle</dt> +<dd><p>The relative height of the middle plot, if more +than two rows of plots are shown.</p></dd> +<dt>row_layout</dt> +<dd><p>Should we use a row layout where the residual plot or the +error model plot is shown to the right?</p></dd> +<dt>lpos</dt> +<dd><p>Position(s) of the legend(s). Passed to <code><a href="https://rdrr.io/r/graphics/legend.html" class="external-link">legend</a></code> as the first argument. If not length one, this should be of the same length -as the obs_var argument.</p></td> - </tr> - <tr> - <th>inset</th> - <td><p>Passed to <code><a href='https://rdrr.io/r/graphics/legend.html'>legend</a></code> if applicable.</p></td> - </tr> - <tr> - <th>show_errmin</th> - <td><p>Should the FOCUS chi2 error value be shown in the upper -margin of the plot?</p></td> - </tr> - <tr> - <th>errmin_digits</th> - <td><p>The number of significant digits for rounding the FOCUS -chi2 error percentage.</p></td> - </tr> - <tr> - <th>frame</th> - <td><p>Should a frame be drawn around the plots?</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Further arguments passed to <code><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></code>.</p></td> - </tr> - <tr> - <th>standardized</th> - <td><p>When calling 'plot_res', should the residuals be -standardized in the residual plot?</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - +as the obs_var argument.</p></dd> +<dt>inset</dt> +<dd><p>Passed to <code><a href="https://rdrr.io/r/graphics/legend.html" class="external-link">legend</a></code> if applicable.</p></dd> +<dt>show_errmin</dt> +<dd><p>Should the FOCUS chi2 error value be shown in the upper +margin of the plot?</p></dd> +<dt>errmin_digits</dt> +<dd><p>The number of significant digits for rounding the FOCUS +chi2 error percentage.</p></dd> +<dt>frame</dt> +<dd><p>Should a frame be drawn around the plots?</p></dd> +<dt>...</dt> +<dd><p>Further arguments passed to <code><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></code>.</p></dd> +<dt>standardized</dt> +<dd><p>When calling 'plot_res', should the residuals be +standardized in the residual plot?</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The function is called for its side effect.</p> - <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2> - - <p>If the current plot device is a <code><a href='https://rdrr.io/pkg/tikzDevice/man/tikz.html'>tikz</a></code> device, then + </div> + <div id="details"> + <h2>Details</h2> + <p>If the current plot device is a <code><a href="https://rdrr.io/pkg/tikzDevice/man/tikz.html" class="external-link">tikz</a></code> device, then latex is being used for the formatting of the chi2 error level, if <code>show_errmin = TRUE</code>.</p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='co'># One parent compound, one metabolite, both single first order, path from</span> -<span class='co'># parent to sink included</span> -<span class='co'># \dontrun{</span> -<span class='va'>SFO_SFO</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"m1"</span>, full <span class='op'>=</span> <span class='st'>"Parent"</span><span class='op'>)</span>, - m1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, full <span class='op'>=</span> <span class='st'>"Metabolite M1"</span> <span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'><span class='va'>fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_2006_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='warning'>Warning: Observations with value of zero were removed from the data</span></div><div class='input'><span class='va'>fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_2006_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='warning'>Warning: Observations with value of zero were removed from the data</span></div><div class='input'><span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span> -</div><div class='img'><img src='plot.mkinfit-1.png' alt='' width='700' height='433' /></div><div class='input'><span class='fu'>plot_res</span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span> -</div><div class='img'><img src='plot.mkinfit-2.png' alt='' width='700' height='433' /></div><div class='input'><span class='fu'>plot_res</span><span class='op'>(</span><span class='va'>fit</span>, standardized <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span> -</div><div class='img'><img src='plot.mkinfit-3.png' alt='' width='700' height='433' /></div><div class='input'><span class='fu'>plot_err</span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span> -</div><div class='img'><img src='plot.mkinfit-4.png' alt='' width='700' height='433' /></div><div class='input'> -<span class='co'># Show the observed variables separately, with residuals</span> -<span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>fit</span>, sep_obs <span class='op'>=</span> <span class='cn'>TRUE</span>, show_residuals <span class='op'>=</span> <span class='cn'>TRUE</span>, lpos <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"topright"</span>, <span class='st'>"bottomright"</span><span class='op'>)</span>, - show_errmin <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='img'><img src='plot.mkinfit-5.png' alt='' width='700' height='433' /></div><div class='input'> -<span class='co'># The same can be obtained with less typing, using the convenience function plot_sep</span> -<span class='fu'>plot_sep</span><span class='op'>(</span><span class='va'>fit</span>, lpos <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"topright"</span>, <span class='st'>"bottomright"</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='img'><img src='plot.mkinfit-6.png' alt='' width='700' height='433' /></div><div class='input'> -<span class='co'># Show the observed variables separately, with the error model</span> -<span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>fit</span>, sep_obs <span class='op'>=</span> <span class='cn'>TRUE</span>, show_errplot <span class='op'>=</span> <span class='cn'>TRUE</span>, lpos <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"topright"</span>, <span class='st'>"bottomright"</span><span class='op'>)</span>, - show_errmin <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='img'><img src='plot.mkinfit-7.png' alt='' width='700' height='433' /></div><div class='input'><span class='co'># }</span> - -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="co"># One parent compound, one metabolite, both single first order, path from</span></span> +<span class="r-in"><span class="co"># parent to sink included</span></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="va">SFO_SFO</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"m1"</span>, full <span class="op">=</span> <span class="st">"Parent"</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, full <span class="op">=</span> <span class="st">"Metabolite M1"</span> <span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="va">fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_2006_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_2006_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"tc"</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></span> +<span class="r-plt img"><img src="plot.mkinfit-1.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="fu">plot_res</span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></span> +<span class="r-plt img"><img src="plot.mkinfit-2.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="fu">plot_res</span><span class="op">(</span><span class="va">fit</span>, standardized <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span></span> +<span class="r-plt img"><img src="plot.mkinfit-3.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="fu">plot_err</span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></span> +<span class="r-plt img"><img src="plot.mkinfit-4.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Show the observed variables separately, with residuals</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">fit</span>, sep_obs <span class="op">=</span> <span class="cn">TRUE</span>, show_residuals <span class="op">=</span> <span class="cn">TRUE</span>, lpos <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"topright"</span>, <span class="st">"bottomright"</span><span class="op">)</span>,</span> +<span class="r-in"> show_errmin <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-plt img"><img src="plot.mkinfit-5.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># The same can be obtained with less typing, using the convenience function plot_sep</span></span> +<span class="r-in"><span class="fu">plot_sep</span><span class="op">(</span><span class="va">fit</span>, lpos <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"topright"</span>, <span class="st">"bottomright"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-plt img"><img src="plot.mkinfit-6.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Show the observed variables separately, with the error model</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">fit</span>, sep_obs <span class="op">=</span> <span class="cn">TRUE</span>, show_errplot <span class="op">=</span> <span class="cn">TRUE</span>, lpos <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"topright"</span>, <span class="st">"bottomright"</span><span class="op">)</span>,</span> +<span class="r-in"> show_errmin <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-plt img"><img src="plot.mkinfit-7.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="co"># }</span></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/plot.mmkin-1.png b/docs/reference/plot.mmkin-1.png Binary files differindex d06d683c..235e33a7 100644 --- a/docs/reference/plot.mmkin-1.png +++ b/docs/reference/plot.mmkin-1.png diff --git a/docs/reference/plot.mmkin-2.png b/docs/reference/plot.mmkin-2.png Binary files differindex d3678aca..7af84edf 100644 --- a/docs/reference/plot.mmkin-2.png +++ b/docs/reference/plot.mmkin-2.png diff --git a/docs/reference/plot.mmkin-3.png b/docs/reference/plot.mmkin-3.png Binary files differindex f84d5782..56bfac50 100644 --- a/docs/reference/plot.mmkin-3.png +++ b/docs/reference/plot.mmkin-3.png diff --git a/docs/reference/plot.mmkin-4.png b/docs/reference/plot.mmkin-4.png Binary files differindex 9919dacb..5da05f40 100644 --- a/docs/reference/plot.mmkin-4.png +++ b/docs/reference/plot.mmkin-4.png diff --git a/docs/reference/plot.mmkin-5.png b/docs/reference/plot.mmkin-5.png Binary files differindex 945b863f..3ec224f4 100644 --- a/docs/reference/plot.mmkin-5.png +++ b/docs/reference/plot.mmkin-5.png diff --git a/docs/reference/plot.mmkin.html b/docs/reference/plot.mmkin.html index 3348e050..0994c4b6 100644 --- a/docs/reference/plot.mmkin.html +++ b/docs/reference/plot.mmkin.html @@ -1,71 +1,16 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Plot model fits (observed and fitted) and the residuals for a row or column -of an mmkin object — plot.mmkin • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Plot model fits (observed and fitted) and the residuals for a row or column -of an mmkin object — plot.mmkin" /> -<meta property="og:description" content="When x is a row selected from an mmkin object ([.mmkin), the +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Plot model fits (observed and fitted) and the residuals for a row or column +of an mmkin object — plot.mmkin • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Plot model fits (observed and fitted) and the residuals for a row or column +of an mmkin object — plot.mmkin"><meta property="og:description" content="When x is a row selected from an mmkin object ([.mmkin), the same model fitted for at least one dataset is shown. When it is a column, -the fit of at least one model to the same dataset is shown." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +the fit of at least one model to the same dataset is shown."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -76,13 +21,12 @@ the fit of at least one model to the same dataset is shown." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -91,8 +35,7 @@ the fit of at least one model to the same dataset is shown." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -102,6 +45,9 @@ the fit of at least one model to the same dataset is shown." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -116,186 +62,158 @@ the fit of at least one model to the same dataset is shown." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Plot model fits (observed and fitted) and the residuals for a row or column of an mmkin object</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/plot.mmkin.R'><code>R/plot.mmkin.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/plot.mmkin.R" class="external-link"><code>R/plot.mmkin.R</code></a></small> <div class="hidden name"><code>plot.mmkin.Rd</code></div> </div> <div class="ref-description"> - <p>When x is a row selected from an mmkin object (<code><a href='[.mmkin.html'>[.mmkin</a></code>), the + <p>When x is a row selected from an mmkin object (<code><a href="Extract.mmkin.html">[.mmkin</a></code>), the same model fitted for at least one dataset is shown. When it is a column, the fit of at least one model to the same dataset is shown.</p> </div> - <pre class="usage"><span class='co'># S3 method for mmkin</span> -<span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span> - <span class='va'>x</span>, - main <span class='op'>=</span> <span class='st'>"auto"</span>, - legends <span class='op'>=</span> <span class='fl'>1</span>, - resplot <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"time"</span>, <span class='st'>"errmod"</span><span class='op'>)</span>, - ylab <span class='op'>=</span> <span class='st'>"Residue"</span>, - standardized <span class='op'>=</span> <span class='cn'>FALSE</span>, - show_errmin <span class='op'>=</span> <span class='cn'>TRUE</span>, - errmin_var <span class='op'>=</span> <span class='st'>"All data"</span>, - errmin_digits <span class='op'>=</span> <span class='fl'>3</span>, - cex <span class='op'>=</span> <span class='fl'>0.7</span>, - rel.height.middle <span class='op'>=</span> <span class='fl'>0.9</span>, - ymax <span class='op'>=</span> <span class='st'>"auto"</span>, - <span class='va'>...</span> -<span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>x</th> - <td><p>An object of class <code><a href='mmkin.html'>mmkin</a></code>, with either one row or one -column.</p></td> - </tr> - <tr> - <th>main</th> - <td><p>The main title placed on the outer margin of the plot.</p></td> - </tr> - <tr> - <th>legends</th> - <td><p>An index for the fits for which legends should be shown.</p></td> - </tr> - <tr> - <th>resplot</th> - <td><p>Should the residuals plotted against time, using -<code><a href='mkinresplot.html'>mkinresplot</a></code>, or as squared residuals against predicted -values, with the error model, using <code><a href='mkinerrplot.html'>mkinerrplot</a></code>.</p></td> - </tr> - <tr> - <th>ylab</th> - <td><p>Label for the y axis.</p></td> - </tr> - <tr> - <th>standardized</th> - <td><p>Should the residuals be standardized? This option -is passed to <code><a href='mkinresplot.html'>mkinresplot</a></code>, it only takes effect if -<code>resplot = "time"</code>.</p></td> - </tr> - <tr> - <th>show_errmin</th> - <td><p>Should the chi2 error level be shown on top of the plots -to the left?</p></td> - </tr> - <tr> - <th>errmin_var</th> - <td><p>The variable for which the FOCUS chi2 error value should -be shown.</p></td> - </tr> - <tr> - <th>errmin_digits</th> - <td><p>The number of significant digits for rounding the FOCUS -chi2 error percentage.</p></td> - </tr> - <tr> - <th>cex</th> - <td><p>Passed to the plot functions and <code><a href='https://rdrr.io/r/graphics/mtext.html'>mtext</a></code>.</p></td> - </tr> - <tr> - <th>rel.height.middle</th> - <td><p>The relative height of the middle plot, if more -than two rows of plots are shown.</p></td> - </tr> - <tr> - <th>ymax</th> - <td><p>Maximum y axis value for <code><a href='plot.mkinfit.html'>plot.mkinfit</a></code>.</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Further arguments passed to <code><a href='plot.mkinfit.html'>plot.mkinfit</a></code> and -<code><a href='mkinresplot.html'>mkinresplot</a></code>.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for mmkin</span> +<span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span> + <span class="va">x</span>, + main <span class="op">=</span> <span class="st">"auto"</span>, + legends <span class="op">=</span> <span class="fl">1</span>, + resplot <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"time"</span>, <span class="st">"errmod"</span><span class="op">)</span>, + ylab <span class="op">=</span> <span class="st">"Residue"</span>, + standardized <span class="op">=</span> <span class="cn">FALSE</span>, + show_errmin <span class="op">=</span> <span class="cn">TRUE</span>, + errmin_var <span class="op">=</span> <span class="st">"All data"</span>, + errmin_digits <span class="op">=</span> <span class="fl">3</span>, + cex <span class="op">=</span> <span class="fl">0.7</span>, + rel.height.middle <span class="op">=</span> <span class="fl">0.9</span>, + ymax <span class="op">=</span> <span class="st">"auto"</span>, + <span class="va">...</span> +<span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>x</dt> +<dd><p>An object of class <code><a href="mmkin.html">mmkin</a></code>, with either one row or one +column.</p></dd> +<dt>main</dt> +<dd><p>The main title placed on the outer margin of the plot.</p></dd> +<dt>legends</dt> +<dd><p>An index for the fits for which legends should be shown.</p></dd> +<dt>resplot</dt> +<dd><p>Should the residuals plotted against time, using +<code><a href="mkinresplot.html">mkinresplot</a></code>, or as squared residuals against predicted +values, with the error model, using <code><a href="mkinerrplot.html">mkinerrplot</a></code>.</p></dd> +<dt>ylab</dt> +<dd><p>Label for the y axis.</p></dd> +<dt>standardized</dt> +<dd><p>Should the residuals be standardized? This option +is passed to <code><a href="mkinresplot.html">mkinresplot</a></code>, it only takes effect if +<code>resplot = "time"</code>.</p></dd> +<dt>show_errmin</dt> +<dd><p>Should the chi2 error level be shown on top of the plots +to the left?</p></dd> +<dt>errmin_var</dt> +<dd><p>The variable for which the FOCUS chi2 error value should +be shown.</p></dd> +<dt>errmin_digits</dt> +<dd><p>The number of significant digits for rounding the FOCUS +chi2 error percentage.</p></dd> +<dt>cex</dt> +<dd><p>Passed to the plot functions and <code><a href="https://rdrr.io/r/graphics/mtext.html" class="external-link">mtext</a></code>.</p></dd> +<dt>rel.height.middle</dt> +<dd><p>The relative height of the middle plot, if more +than two rows of plots are shown.</p></dd> +<dt>ymax</dt> +<dd><p>Maximum y axis value for <code><a href="plot.mkinfit.html">plot.mkinfit</a></code>.</p></dd> +<dt>...</dt> +<dd><p>Further arguments passed to <code><a href="plot.mkinfit.html">plot.mkinfit</a></code> and +<code><a href="mkinresplot.html">mkinresplot</a></code>.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The function is called for its side effect.</p> - <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2> - - <p>If the current plot device is a <code><a href='https://rdrr.io/pkg/tikzDevice/man/tikz.html'>tikz</a></code> device, then + </div> + <div id="details"> + <h2>Details</h2> + <p>If the current plot device is a <code><a href="https://rdrr.io/pkg/tikzDevice/man/tikz.html" class="external-link">tikz</a></code> device, then latex is being used for the formatting of the chi2 error level.</p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> - <span class='co'># \dontrun{</span> - <span class='co'># Only use one core not to offend CRAN checks</span> - <span class='va'>fits</span> <span class='op'><-</span> <span class='fu'><a href='mmkin.html'>mmkin</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"FOMC"</span>, <span class='st'>"HS"</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span><span class='st'>"FOCUS B"</span> <span class='op'>=</span> <span class='va'>FOCUS_2006_B</span>, <span class='st'>"FOCUS C"</span> <span class='op'>=</span> <span class='va'>FOCUS_2006_C</span><span class='op'>)</span>, <span class='co'># named list for titles</span> - cores <span class='op'>=</span> <span class='fl'>1</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='warning'>Warning: Optimisation did not converge:</span> -#> <span class='warning'>iteration limit reached without convergence (10)</span></div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>fits</span><span class='op'>[</span>, <span class='st'>"FOCUS C"</span><span class='op'>]</span><span class='op'>)</span> -</div><div class='img'><img src='plot.mmkin-1.png' alt='' width='700' height='433' /></div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>fits</span><span class='op'>[</span><span class='st'>"FOMC"</span>, <span class='op'>]</span><span class='op'>)</span> -</div><div class='img'><img src='plot.mmkin-2.png' alt='' width='700' height='433' /></div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>fits</span><span class='op'>[</span><span class='st'>"FOMC"</span>, <span class='op'>]</span>, show_errmin <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span> -</div><div class='img'><img src='plot.mmkin-3.png' alt='' width='700' height='433' /></div><div class='input'> - <span class='co'># We can also plot a single fit, if we like the way plot.mmkin works, but then the plot</span> - <span class='co'># height should be smaller than the plot width (this is not possible for the html pages</span> - <span class='co'># generated by pkgdown, as far as I know).</span> - <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>fits</span><span class='op'>[</span><span class='st'>"FOMC"</span>, <span class='st'>"FOCUS C"</span><span class='op'>]</span><span class='op'>)</span> <span class='co'># same as plot(fits[1, 2])</span> -</div><div class='img'><img src='plot.mmkin-4.png' alt='' width='700' height='433' /></div><div class='input'> - <span class='co'># Show the error models</span> - <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>fits</span><span class='op'>[</span><span class='st'>"FOMC"</span>, <span class='op'>]</span>, resplot <span class='op'>=</span> <span class='st'>"errmod"</span><span class='op'>)</span> -</div><div class='img'><img src='plot.mmkin-5.png' alt='' width='700' height='433' /></div><div class='input'> <span class='co'># }</span> - -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"> <span class="co"># \dontrun{</span></span> +<span class="r-in"> <span class="co"># Only use one core not to offend CRAN checks</span></span> +<span class="r-in"> <span class="va">fits</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"FOMC"</span>, <span class="st">"HS"</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="st">"FOCUS B"</span> <span class="op">=</span> <span class="va">FOCUS_2006_B</span>, <span class="st">"FOCUS C"</span> <span class="op">=</span> <span class="va">FOCUS_2006_C</span><span class="op">)</span>, <span class="co"># named list for titles</span></span> +<span class="r-in"> cores <span class="op">=</span> <span class="fl">1</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"tc"</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">fits</span><span class="op">[</span>, <span class="st">"FOCUS C"</span><span class="op">]</span><span class="op">)</span></span> +<span class="r-plt img"><img src="plot.mmkin-1.png" alt="" width="700" height="433"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">fits</span><span class="op">[</span><span class="st">"FOMC"</span>, <span class="op">]</span><span class="op">)</span></span> +<span class="r-plt img"><img src="plot.mmkin-2.png" alt="" width="700" height="433"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">fits</span><span class="op">[</span><span class="st">"FOMC"</span>, <span class="op">]</span>, show_errmin <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span></span> +<span class="r-plt img"><img src="plot.mmkin-3.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +<span class="r-in"> <span class="co"># We can also plot a single fit, if we like the way plot.mmkin works, but then the plot</span></span> +<span class="r-in"> <span class="co"># height should be smaller than the plot width (this is not possible for the html pages</span></span> +<span class="r-in"> <span class="co"># generated by pkgdown, as far as I know).</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">fits</span><span class="op">[</span><span class="st">"FOMC"</span>, <span class="st">"FOCUS C"</span><span class="op">]</span><span class="op">)</span> <span class="co"># same as plot(fits[1, 2])</span></span> +<span class="r-plt img"><img src="plot.mmkin-4.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +<span class="r-in"> <span class="co"># Show the error models</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">fits</span><span class="op">[</span><span class="st">"FOMC"</span>, <span class="op">]</span>, resplot <span class="op">=</span> <span class="st">"errmod"</span><span class="op">)</span></span> +<span class="r-plt img"><img src="plot.mmkin-5.png" alt="" width="700" height="433"></span> +<span class="r-in"> <span class="co"># }</span></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/plot.nafta.html b/docs/reference/plot.nafta.html index 544ee5eb..d3407a24 100644 --- a/docs/reference/plot.nafta.html +++ b/docs/reference/plot.nafta.html @@ -1,68 +1,13 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Plot the results of the three models used in the NAFTA scheme. — plot.nafta • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Plot the results of the three models used in the NAFTA scheme. — plot.nafta" /> -<meta property="og:description" content="The plots are ordered with increasing complexity of the model in this -function (SFO, then IORE, then DFOP)." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Plot the results of the three models used in the NAFTA scheme. — plot.nafta • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Plot the results of the three models used in the NAFTA scheme. — plot.nafta"><meta property="og:description" content="The plots are ordered with increasing complexity of the model in this +function (SFO, then IORE, then DFOP)."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -73,13 +18,12 @@ function (SFO, then IORE, then DFOP)." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -88,8 +32,7 @@ function (SFO, then IORE, then DFOP)." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -99,6 +42,9 @@ function (SFO, then IORE, then DFOP)." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -113,34 +59,27 @@ function (SFO, then IORE, then DFOP)." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Plot the results of the three models used in the NAFTA scheme.</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/nafta.R'><code>R/nafta.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/nafta.R" class="external-link"><code>R/nafta.R</code></a></small> <div class="hidden name"><code>plot.nafta.Rd</code></div> </div> @@ -149,65 +88,56 @@ function (SFO, then IORE, then DFOP)." /> function (SFO, then IORE, then DFOP).</p> </div> - <pre class="usage"><span class='co'># S3 method for nafta</span> -<span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>x</span>, legend <span class='op'>=</span> <span class='cn'>FALSE</span>, main <span class='op'>=</span> <span class='st'>"auto"</span>, <span class='va'>...</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>x</th> - <td><p>An object of class <code><a href='nafta.html'>nafta</a></code>.</p></td> - </tr> - <tr> - <th>legend</th> - <td><p>Should a legend be added?</p></td> - </tr> - <tr> - <th>main</th> - <td><p>Possibility to override the main title of the plot.</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Further arguments passed to <code><a href='plot.mmkin.html'>plot.mmkin</a></code>.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for nafta</span> +<span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">x</span>, legend <span class="op">=</span> <span class="cn">FALSE</span>, main <span class="op">=</span> <span class="st">"auto"</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>x</dt> +<dd><p>An object of class <code><a href="nafta.html">nafta</a></code>.</p></dd> +<dt>legend</dt> +<dd><p>Should a legend be added?</p></dd> +<dt>main</dt> +<dd><p>Possibility to override the main title of the plot.</p></dd> +<dt>...</dt> +<dd><p>Further arguments passed to <code><a href="plot.mmkin.html">plot.mmkin</a></code>.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The function is called for its side effect.</p> - <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2> - - <p>Calls <code><a href='plot.mmkin.html'>plot.mmkin</a></code>.</p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - + </div> + <div id="details"> + <h2>Details</h2> + <p>Calls <code><a href="plot.mmkin.html">plot.mmkin</a></code>.</p> + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/reexports.html b/docs/reference/reexports.html index e195d8bf..22180913 100644 --- a/docs/reference/reexports.html +++ b/docs/reference/reexports.html @@ -1,74 +1,27 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Objects exported from other packages — reexports • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Objects exported from other packages — reexports" /> -<meta property="og:description" content="These objects are imported from other packages. Follow the links +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Objects exported from other packages — reexports • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Objects exported from other packages — reexports"><meta property="og:description" content="These objects are imported from other packages. Follow the links below to see their documentation. - lmtestlrtest - - nlmenlme + lmtest +lrtest -" /> + nlme +intervals, nlme + nlmixr +nlmixr -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> -<!--[if lt IE 9]> +"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -79,13 +32,12 @@ below to see their documentation. </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.5</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -94,8 +46,7 @@ below to see their documentation. <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -105,6 +56,9 @@ below to see their documentation. <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -119,76 +73,70 @@ below to see their documentation. <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Objects exported from other packages</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/lrtest.mkinfit.R'><code>R/lrtest.mkinfit.R</code></a>, <a href='https://github.com/jranke/mkin/blob/master/R/nlme.mmkin.R'><code>R/nlme.mmkin.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/intervals.R" class="external-link"><code>R/intervals.R</code></a>, <a href="https://github.com/jranke/mkin/blob/HEAD/R/lrtest.mkinfit.R" class="external-link"><code>R/lrtest.mkinfit.R</code></a>, <a href="https://github.com/jranke/mkin/blob/HEAD/R/nlme.mmkin.R" class="external-link"><code>R/nlme.mmkin.R</code></a>, and 1 more</small> <div class="hidden name"><code>reexports.Rd</code></div> </div> <div class="ref-description"> <p>These objects are imported from other packages. Follow the links below to see their documentation.</p> -<dl> - <dt>lmtest</dt><dd><p><code><a href='https://rdrr.io/pkg/lmtest/man/lrtest.html'>lrtest</a></code></p></dd> +<dl><dt>lmtest</dt> +<dd><p><code><a href="https://rdrr.io/pkg/lmtest/man/lrtest.html" class="external-link">lrtest</a></code></p></dd> - <dt>nlme</dt><dd><p><code><a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme</a></code></p></dd> -</dl> - </div> + <dt>nlme</dt> +<dd><p><code><a href="https://rdrr.io/pkg/nlme/man/intervals.html" class="external-link">intervals</a></code>, <code><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></code></p></dd> + + + <dt>nlmixr</dt> +<dd><p><code><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></code></p></dd> +</dl></div> + </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/residuals.mkinfit.html b/docs/reference/residuals.mkinfit.html index c5c2dcaf..19e077c5 100644 --- a/docs/reference/residuals.mkinfit.html +++ b/docs/reference/residuals.mkinfit.html @@ -1,67 +1,12 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Extract residuals from an mkinfit model — residuals.mkinfit • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Extract residuals from an mkinfit model — residuals.mkinfit" /> -<meta property="og:description" content="Extract residuals from an mkinfit model" /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Extract residuals from an mkinfit model — residuals.mkinfit • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Extract residuals from an mkinfit model — residuals.mkinfit"><meta property="og:description" content="Extract residuals from an mkinfit model"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -72,13 +17,12 @@ </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -87,8 +31,7 @@ <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -98,6 +41,9 @@ <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -112,34 +58,27 @@ <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Extract residuals from an mkinfit model</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/residuals.mkinfit.R'><code>R/residuals.mkinfit.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/residuals.mkinfit.R" class="external-link"><code>R/residuals.mkinfit.R</code></a></small> <div class="hidden name"><code>residuals.mkinfit.Rd</code></div> </div> @@ -147,60 +86,54 @@ <p>Extract residuals from an mkinfit model</p> </div> - <pre class="usage"><span class='co'># S3 method for mkinfit</span> -<span class='fu'><a href='https://rdrr.io/r/stats/residuals.html'>residuals</a></span><span class='op'>(</span><span class='va'>object</span>, standardized <span class='op'>=</span> <span class='cn'>FALSE</span>, <span class='va'>...</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>A <code><a href='mkinfit.html'>mkinfit</a></code> object</p></td> - </tr> - <tr> - <th>standardized</th> - <td><p>Should the residuals be standardized by dividing by the -standard deviation obtained from the fitted error model?</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Not used</p></td> - </tr> - </table> - - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='va'>f</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"DFOP"</span>, <span class='va'>FOCUS_2006_C</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/stats/residuals.html'>residuals</a></span><span class='op'>(</span><span class='va'>f</span><span class='op'>)</span> -</div><div class='output co'>#> [1] 0.09726374 -0.13912142 -0.15351210 0.73388322 -0.08657004 -0.93204702 -#> [7] -0.03269080 1.45347823 -0.88423697</div><div class='input'><span class='fu'><a href='https://rdrr.io/r/stats/residuals.html'>residuals</a></span><span class='op'>(</span><span class='va'>f</span>, standardized <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> [1] 0.13969917 -0.19981904 -0.22048826 1.05407091 -0.12433989 -1.33869208 -#> [7] -0.04695355 2.08761977 -1.27002287</div></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for mkinfit</span> +<span class="fu"><a href="https://rdrr.io/r/stats/residuals.html" class="external-link">residuals</a></span><span class="op">(</span><span class="va">object</span>, standardized <span class="op">=</span> <span class="cn">FALSE</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>A <code><a href="mkinfit.html">mkinfit</a></code> object</p></dd> +<dt>standardized</dt> +<dd><p>Should the residuals be standardized by dividing by the +standard deviation obtained from the fitted error model?</p></dd> +<dt>...</dt> +<dd><p>Not used</p></dd> +</dl></div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="va">f</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="va">FOCUS_2006_C</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/stats/residuals.html" class="external-link">residuals</a></span><span class="op">(</span><span class="va">f</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 0.09726374 -0.13912142 -0.15351210 0.73388322 -0.08657004 -0.93204702</span> +<span class="r-out co"><span class="r-pr">#></span> [7] -0.03269080 1.45347823 -0.88423697</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/stats/residuals.html" class="external-link">residuals</a></span><span class="op">(</span><span class="va">f</span>, standardized <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 0.13969917 -0.19981904 -0.22048826 1.05407091 -0.12433989 -1.33869208</span> +<span class="r-out co"><span class="r-pr">#></span> [7] -0.04695355 2.08761977 -1.27002287</span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/saem.html b/docs/reference/saem.html new file mode 100644 index 00000000..8b86b5a2 --- /dev/null +++ b/docs/reference/saem.html @@ -0,0 +1,327 @@ +<!DOCTYPE html> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Fit nonlinear mixed models with SAEM — saem • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Fit nonlinear mixed models with SAEM — saem"><meta property="og:description" content="This function uses saemix::saemix() as a backend for fitting nonlinear mixed +effects models created from mmkin row objects using the Stochastic Approximation +Expectation Maximisation algorithm (SAEM)."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> +<script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> +<script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + + + <div class="container template-reference-topic"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <div class="container"> + <div class="navbar-header"> + <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> + <span class="sr-only">Toggle navigation</span> + <span class="icon-bar"></span> + <span class="icon-bar"></span> + <span class="icon-bar"></span> + </button> + <span class="navbar-brand"> + <a class="navbar-link" href="../index.html">mkin</a> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> + </span> + </div> + + <div id="navbar" class="navbar-collapse collapse"> + <ul class="nav navbar-nav"><li> + <a href="../reference/index.html">Functions and data</a> +</li> +<li class="dropdown"> + <a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-expanded="false"> + Articles + + <span class="caret"></span> + </a> + <ul class="dropdown-menu" role="menu"><li> + <a href="../articles/mkin.html">Introduction to mkin</a> + </li> + <li> + <a href="../articles/FOCUS_D.html">Example evaluation of FOCUS Example Dataset D</a> + </li> + <li> + <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> + </li> + <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> + <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> + </li> + <li> + <a href="../articles/web_only/compiled_models.html">Performance benefit by using compiled model definitions in mkin</a> + </li> + <li> + <a href="../articles/twa.html">Calculation of time weighted average concentrations with mkin</a> + </li> + <li> + <a href="../articles/web_only/NAFTA_examples.html">Example evaluation of NAFTA SOP Attachment examples</a> + </li> + <li> + <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> + </li> + </ul></li> +<li> + <a href="../news/index.html">News</a> +</li> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> + <span class="fab fa-github fa-lg"></span> + + </a> +</li> + </ul></div><!--/.nav-collapse --> + </div><!--/.container --> +</div><!--/.navbar --> + + + + </header><div class="row"> + <div class="col-md-9 contents"> + <div class="page-header"> + <h1>Fit nonlinear mixed models with SAEM</h1> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/saem.R" class="external-link"><code>R/saem.R</code></a></small> + <div class="hidden name"><code>saem.Rd</code></div> + </div> + + <div class="ref-description"> + <p>This function uses <code><a href="https://rdrr.io/pkg/saemix/man/saemix.html" class="external-link">saemix::saemix()</a></code> as a backend for fitting nonlinear mixed +effects models created from <a href="mmkin.html">mmkin</a> row objects using the Stochastic Approximation +Expectation Maximisation algorithm (SAEM).</p> + </div> + + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">saem</span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span><span class="op">)</span> + +<span class="co"># S3 method for mmkin</span> +<span class="fu">saem</span><span class="op">(</span> + <span class="va">object</span>, + transformations <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"mkin"</span>, <span class="st">"saemix"</span><span class="op">)</span>, + degparms_start <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/numeric.html" class="external-link">numeric</a></span><span class="op">(</span><span class="op">)</span>, + test_log_parms <span class="op">=</span> <span class="cn">TRUE</span>, + conf.level <span class="op">=</span> <span class="fl">0.6</span>, + solution_type <span class="op">=</span> <span class="st">"auto"</span>, + nbiter.saemix <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">300</span>, <span class="fl">100</span><span class="op">)</span>, + control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>displayProgress <span class="op">=</span> <span class="cn">FALSE</span>, print <span class="op">=</span> <span class="cn">FALSE</span>, nbiter.saemix <span class="op">=</span> <span class="va">nbiter.saemix</span>, + save <span class="op">=</span> <span class="cn">FALSE</span>, save.graphs <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span>, + fail_with_errors <span class="op">=</span> <span class="cn">TRUE</span>, + verbose <span class="op">=</span> <span class="cn">FALSE</span>, + quiet <span class="op">=</span> <span class="cn">FALSE</span>, + <span class="va">...</span> +<span class="op">)</span> + +<span class="co"># S3 method for saem.mmkin</span> +<span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">x</span>, digits <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/Extremes.html" class="external-link">max</a></span><span class="op">(</span><span class="fl">3</span>, <span class="fu"><a href="https://rdrr.io/r/base/options.html" class="external-link">getOption</a></span><span class="op">(</span><span class="st">"digits"</span><span class="op">)</span> <span class="op">-</span> <span class="fl">3</span><span class="op">)</span>, <span class="va">...</span><span class="op">)</span> + +<span class="fu">saemix_model</span><span class="op">(</span> + <span class="va">object</span>, + solution_type <span class="op">=</span> <span class="st">"auto"</span>, + transformations <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"mkin"</span>, <span class="st">"saemix"</span><span class="op">)</span>, + degparms_start <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/numeric.html" class="external-link">numeric</a></span><span class="op">(</span><span class="op">)</span>, + test_log_parms <span class="op">=</span> <span class="cn">FALSE</span>, + conf.level <span class="op">=</span> <span class="fl">0.6</span>, + verbose <span class="op">=</span> <span class="cn">FALSE</span>, + <span class="va">...</span> +<span class="op">)</span> + +<span class="fu">saemix_data</span><span class="op">(</span><span class="va">object</span>, verbose <span class="op">=</span> <span class="cn">FALSE</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>An <a href="mmkin.html">mmkin</a> row object containing several fits of the same +<a href="mkinmod.html">mkinmod</a> model to different datasets</p></dd> +<dt>...</dt> +<dd><p>Further parameters passed to <a href="https://rdrr.io/pkg/saemix/man/saemixModel.html" class="external-link">saemix::saemixModel</a>.</p></dd> +<dt>transformations</dt> +<dd><p>Per default, all parameter transformations are done +in mkin. If this argument is set to 'saemix', parameter transformations +are done in 'saemix' for the supported cases. Currently this is only +supported in cases where the initial concentration of the parent is not fixed, +SFO or DFOP is used for the parent and there is either no metabolite or one.</p></dd> +<dt>degparms_start</dt> +<dd><p>Parameter values given as a named numeric vector will +be used to override the starting values obtained from the 'mmkin' object.</p></dd> +<dt>test_log_parms</dt> +<dd><p>If TRUE, an attempt is made to use more robust starting +values for population parameters fitted as log parameters in mkin (like +rate constants) by only considering rate constants that pass the t-test +when calculating mean degradation parameters using <a href="mean_degparms.html">mean_degparms</a>.</p></dd> +<dt>conf.level</dt> +<dd><p>Possibility to adjust the required confidence level +for parameter that are tested if requested by 'test_log_parms'.</p></dd> +<dt>solution_type</dt> +<dd><p>Possibility to specify the solution type in case the +automatic choice is not desired</p></dd> +<dt>nbiter.saemix</dt> +<dd><p>Convenience option to increase the number of +iterations</p></dd> +<dt>control</dt> +<dd><p>Passed to <a href="https://rdrr.io/pkg/saemix/man/saemix.html" class="external-link">saemix::saemix</a>.</p></dd> +<dt>fail_with_errors</dt> +<dd><p>Should a failure to compute standard errors +from the inverse of the Fisher Information Matrix be a failure?</p></dd> +<dt>verbose</dt> +<dd><p>Should we print information about created objects of +type <a href="https://rdrr.io/pkg/saemix/man/SaemixModel-class.html" class="external-link">saemix::SaemixModel</a> and <a href="https://rdrr.io/pkg/saemix/man/SaemixData-class.html" class="external-link">saemix::SaemixData</a>?</p></dd> +<dt>quiet</dt> +<dd><p>Should we suppress the messages saemix prints at the beginning +and the end of the optimisation process?</p></dd> +<dt>x</dt> +<dd><p>An saem.mmkin object to print</p></dd> +<dt>digits</dt> +<dd><p>Number of digits to use for printing</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>An S3 object of class 'saem.mmkin', containing the fitted +<a href="https://rdrr.io/pkg/saemix/man/SaemixObject-class.html" class="external-link">saemix::SaemixObject</a> as a list component named 'so'. The +object also inherits from 'mixed.mmkin'. +An <a href="https://rdrr.io/pkg/saemix/man/SaemixModel-class.html" class="external-link">saemix::SaemixModel</a> object. +An <a href="https://rdrr.io/pkg/saemix/man/SaemixData-class.html" class="external-link">saemix::SaemixData</a> object.</p> + </div> + <div id="details"> + <h2>Details</h2> + <p>An mmkin row object is essentially a list of mkinfit objects that have been +obtained by fitting the same model to a list of datasets using <a href="mkinfit.html">mkinfit</a>.</p> +<p>Starting values for the fixed effects (population mean parameters, argument +psi0 of <code><a href="https://rdrr.io/pkg/saemix/man/saemixModel.html" class="external-link">saemix::saemixModel()</a></code> are the mean values of the parameters found +using <a href="mmkin.html">mmkin</a>.</p> + </div> + <div id="see-also"> + <h2>See also</h2> + <div class="dont-index"><p><a href="summary.saem.mmkin.html">summary.saem.mmkin</a> <a href="plot.mixed.mmkin.html">plot.mixed.mmkin</a></p></div> + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="va">ds</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="va">experimental_data_for_UBA_2019</span><span class="op">[</span><span class="fl">6</span><span class="op">:</span><span class="fl">10</span><span class="op">]</span>,</span> +<span class="r-in"> <span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu"><a href="https://rdrr.io/r/base/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">x</span><span class="op">$</span><span class="va">data</span><span class="op">[</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"name"</span>, <span class="st">"time"</span>, <span class="st">"value"</span><span class="op">)</span><span class="op">]</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">ds</span><span class="op">)</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste</a></span><span class="op">(</span><span class="st">"Dataset"</span>, <span class="fl">6</span><span class="op">:</span><span class="fl">10</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_mmkin_parent_p0_fixed</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="st">"FOMC"</span>, <span class="va">ds</span>,</span> +<span class="r-in"> state.ini <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span><span class="op">)</span>, fixed_initials <span class="op">=</span> <span class="st">"parent"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_saem_p0_fixed</span> <span class="op"><-</span> <span class="fu">saem</span><span class="op">(</span><span class="va">f_mmkin_parent_p0_fixed</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in rxModelVars_(obj):</span> Not compatible with STRSXP: [type=NULL].</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">f_mmkin_parent</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"FOMC"</span>, <span class="st">"DFOP"</span><span class="op">)</span>, <span class="va">ds</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_saem_sfo</span> <span class="op"><-</span> <span class="fu">saem</span><span class="op">(</span><span class="va">f_mmkin_parent</span><span class="op">[</span><span class="st">"SFO"</span>, <span class="op">]</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in rxModelVars_(obj):</span> Not compatible with STRSXP: [type=NULL].</span> +<span class="r-in"><span class="va">f_saem_fomc</span> <span class="op"><-</span> <span class="fu">saem</span><span class="op">(</span><span class="va">f_mmkin_parent</span><span class="op">[</span><span class="st">"FOMC"</span>, <span class="op">]</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in rxModelVars_(obj):</span> Not compatible with STRSXP: [type=NULL].</span> +<span class="r-in"><span class="va">f_saem_dfop</span> <span class="op"><-</span> <span class="fu">saem</span><span class="op">(</span><span class="va">f_mmkin_parent</span><span class="op">[</span><span class="st">"DFOP"</span>, <span class="op">]</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in rxModelVars_(obj):</span> Not compatible with STRSXP: [type=NULL].</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># The returned saem.mmkin object contains an SaemixObject, therefore we can use</span></span> +<span class="r-in"><span class="co"># functions from saemix</span></span> +<span class="r-in"><span class="kw"><a href="https://rdrr.io/r/base/library.html" class="external-link">library</a></span><span class="op">(</span><span class="va">saemix</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Loading required package: npde</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> Attaching package: ‘npde’</span> +<span class="r-msg co"><span class="r-pr">#></span> The following object is masked from ‘package:nlmixr’:</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> warfarin</span> +<span class="r-msg co"><span class="r-pr">#></span> Package saemix, version 3.0</span> +<span class="r-msg co"><span class="r-pr">#></span> please direct bugs, questions and feedback to emmanuelle.comets@inserm.fr</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> Attaching package: ‘saemix’</span> +<span class="r-msg co"><span class="r-pr">#></span> The following objects are masked from ‘package:npde’:</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> kurtosis, skewness</span> +<span class="r-msg co"><span class="r-pr">#></span> The following object is masked from ‘package:RxODE’:</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> phi</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/saemix/man/compare.saemix.html" class="external-link">compare.saemix</a></span><span class="op">(</span><span class="va">f_saem_sfo</span><span class="op">$</span><span class="va">so</span>, <span class="va">f_saem_fomc</span><span class="op">$</span><span class="va">so</span>, <span class="va">f_saem_dfop</span><span class="op">$</span><span class="va">so</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in compare.saemix(f_saem_sfo$so, f_saem_fomc$so, f_saem_dfop$so):</span> object 'f_saem_sfo' not found</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/saemix/man/plot-SaemixObject-ANY-method.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_saem_fomc</span><span class="op">$</span><span class="va">so</span>, plot.type <span class="op">=</span> <span class="st">"convergence"</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in h(simpleError(msg, call)):</span> error in evaluating the argument 'x' in selecting a method for function 'plot': object 'f_saem_fomc' not found</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/saemix/man/plot-SaemixObject-ANY-method.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_saem_fomc</span><span class="op">$</span><span class="va">so</span>, plot.type <span class="op">=</span> <span class="st">"individual.fit"</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in h(simpleError(msg, call)):</span> error in evaluating the argument 'x' in selecting a method for function 'plot': object 'f_saem_fomc' not found</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/saemix/man/plot-SaemixObject-ANY-method.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_saem_fomc</span><span class="op">$</span><span class="va">so</span>, plot.type <span class="op">=</span> <span class="st">"npde"</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in h(simpleError(msg, call)):</span> error in evaluating the argument 'x' in selecting a method for function 'plot': object 'f_saem_fomc' not found</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/saemix/man/plot-SaemixObject-ANY-method.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_saem_fomc</span><span class="op">$</span><span class="va">so</span>, plot.type <span class="op">=</span> <span class="st">"vpc"</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in h(simpleError(msg, call)):</span> error in evaluating the argument 'x' in selecting a method for function 'plot': object 'f_saem_fomc' not found</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">f_mmkin_parent_tc</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/update.html" class="external-link">update</a></span><span class="op">(</span><span class="va">f_mmkin_parent</span>, error_model <span class="op">=</span> <span class="st">"tc"</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_saem_fomc_tc</span> <span class="op"><-</span> <span class="fu">saem</span><span class="op">(</span><span class="va">f_mmkin_parent_tc</span><span class="op">[</span><span class="st">"FOMC"</span>, <span class="op">]</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in rxModelVars_(obj):</span> Not compatible with STRSXP: [type=NULL].</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/saemix/man/compare.saemix.html" class="external-link">compare.saemix</a></span><span class="op">(</span><span class="va">f_saem_fomc</span><span class="op">$</span><span class="va">so</span>, <span class="va">f_saem_fomc_tc</span><span class="op">$</span><span class="va">so</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in compare.saemix(f_saem_fomc$so, f_saem_fomc_tc$so):</span> object 'f_saem_fomc' not found</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">sfo_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"A1"</span><span class="op">)</span>,</span> +<span class="r-in"> A1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="va">fomc_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"FOMC"</span>, <span class="st">"A1"</span><span class="op">)</span>,</span> +<span class="r-in"> A1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="va">dfop_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="st">"A1"</span><span class="op">)</span>,</span> +<span class="r-in"> A1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"><span class="co"># The following fit uses analytical solutions for SFO-SFO and DFOP-SFO,</span></span> +<span class="r-in"><span class="co"># and compiled ODEs for FOMC that are much slower</span></span> +<span class="r-in"><span class="va">f_mmkin</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span></span> +<span class="r-in"> <span class="st">"SFO-SFO"</span> <span class="op">=</span> <span class="va">sfo_sfo</span>, <span class="st">"FOMC-SFO"</span> <span class="op">=</span> <span class="va">fomc_sfo</span>, <span class="st">"DFOP-SFO"</span> <span class="op">=</span> <span class="va">dfop_sfo</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">ds</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># saem fits of SFO-SFO and DFOP-SFO to these data take about five seconds</span></span> +<span class="r-in"><span class="co"># each on this system, as we use analytical solutions written for saemix.</span></span> +<span class="r-in"><span class="co"># When using the analytical solutions written for mkin this took around</span></span> +<span class="r-in"><span class="co"># four minutes</span></span> +<span class="r-in"><span class="va">f_saem_sfo_sfo</span> <span class="op"><-</span> <span class="fu">saem</span><span class="op">(</span><span class="va">f_mmkin</span><span class="op">[</span><span class="st">"SFO-SFO"</span>, <span class="op">]</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in rxModelVars_(obj):</span> Not compatible with STRSXP: [type=NULL].</span> +<span class="r-in"><span class="va">f_saem_dfop_sfo</span> <span class="op"><-</span> <span class="fu">saem</span><span class="op">(</span><span class="va">f_mmkin</span><span class="op">[</span><span class="st">"DFOP-SFO"</span>, <span class="op">]</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in rxModelVars_(obj):</span> Not compatible with STRSXP: [type=NULL].</span> +<span class="r-in"><span class="co"># We can use print, plot and summary methods to check the results</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">f_saem_dfop_sfo</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in h(simpleError(msg, call)):</span> error in evaluating the argument 'x' in selecting a method for function 'print': object 'f_saem_dfop_sfo' not found</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/saemix/man/plot-SaemixObject-ANY-method.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">f_saem_dfop_sfo</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in h(simpleError(msg, call)):</span> error in evaluating the argument 'x' in selecting a method for function 'plot': object 'f_saem_dfop_sfo' not found</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/saemix/man/summary-methods.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">f_saem_dfop_sfo</span>, data <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in h(simpleError(msg, call)):</span> error in evaluating the argument 'object' in selecting a method for function 'summary': object 'f_saem_dfop_sfo' not found</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># The following takes about 6 minutes</span></span> +<span class="r-in"><span class="co">#f_saem_dfop_sfo_deSolve <- saem(f_mmkin["DFOP-SFO", ], solution_type = "deSolve",</span></span> +<span class="r-in"><span class="co"># control = list(nbiter.saemix = c(200, 80), nbdisplay = 10))</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co">#saemix::compare.saemix(list(</span></span> +<span class="r-in"><span class="co"># f_saem_dfop_sfo$so,</span></span> +<span class="r-in"><span class="co"># f_saem_dfop_sfo_deSolve$so))</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># If the model supports it, we can also use eigenvalue based solutions, which</span></span> +<span class="r-in"><span class="co"># take a similar amount of time</span></span> +<span class="r-in"><span class="co">#f_saem_sfo_sfo_eigen <- saem(f_mmkin["SFO-SFO", ], solution_type = "eigen",</span></span> +<span class="r-in"><span class="co"># control = list(nbiter.saemix = c(200, 80), nbdisplay = 10))</span></span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> + </div> + <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> +</div> + + + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> +</div> + +<div class="pkgdown"> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> +</div> + + </footer></div> + + + + + + + </body></html> + diff --git a/docs/reference/schaefer07_complex_case-1.png b/docs/reference/schaefer07_complex_case-1.png Binary files differindex 96aab2dc..eee9e0cc 100644 --- a/docs/reference/schaefer07_complex_case-1.png +++ b/docs/reference/schaefer07_complex_case-1.png diff --git a/docs/reference/schaefer07_complex_case.html b/docs/reference/schaefer07_complex_case.html index 979e4c29..8c39ca1b 100644 --- a/docs/reference/schaefer07_complex_case.html +++ b/docs/reference/schaefer07_complex_case.html @@ -1,69 +1,14 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Metabolism data set used for checking the software quality of KinGUI — schaefer07_complex_case • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Metabolism data set used for checking the software quality of KinGUI — schaefer07_complex_case" /> -<meta property="og:description" content="This dataset was used for a comparison of KinGUI and ModelMaker to check the +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Metabolism data set used for checking the software quality of KinGUI — schaefer07_complex_case • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Metabolism data set used for checking the software quality of KinGUI — schaefer07_complex_case"><meta property="og:description" content="This dataset was used for a comparison of KinGUI and ModelMaker to check the software quality of KinGUI in the original publication (Schäfer et al., 2007). - The results from the fitting are also included." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> + The results from the fitting are also included."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -74,13 +19,12 @@ </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -89,8 +33,7 @@ <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -100,6 +43,9 @@ <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -114,30 +60,23 @@ <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Metabolism data set used for checking the software quality of KinGUI</h1> @@ -151,93 +90,109 @@ The results from the fitting are also included.</p> </div> - <pre class="usage"><span class='va'>schaefer07_complex_case</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="va">schaefer07_complex_case</span></code></pre></div> + </div> + + <div id="format"> + <h2>Format</h2> + <p>The data set is a data frame with 8 observations on the following 6 variables.</p><dl><dt><code>time</code></dt> +<dd><p>a numeric vector</p></dd> + + <dt><code>parent</code></dt> +<dd><p>a numeric vector</p></dd> + + <dt><code>A1</code></dt> +<dd><p>a numeric vector</p></dd> + <dt><code>B1</code></dt> +<dd><p>a numeric vector</p></dd> - <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2> + <dt><code>C1</code></dt> +<dd><p>a numeric vector</p></dd> + + <dt><code>A2</code></dt> +<dd><p>a numeric vector</p></dd> - <p>The data set is a data frame with 8 observations on the following 6 variables.</p><dl> - <dt><code>time</code></dt><dd><p>a numeric vector</p></dd> - <dt><code>parent</code></dt><dd><p>a numeric vector</p></dd> - <dt><code>A1</code></dt><dd><p>a numeric vector</p></dd> - <dt><code>B1</code></dt><dd><p>a numeric vector</p></dd> - <dt><code>C1</code></dt><dd><p>a numeric vector</p></dd> - <dt><code>A2</code></dt><dd><p>a numeric vector</p></dd> </dl><p>The results are a data frame with 14 results for different parameter values</p> - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - + </div> + <div id="references"> + <h2>References</h2> <p>Schäfer D, Mikolasch B, Rainbird P and Harvey B (2007). KinGUI: a new kinetic software tool for evaluations according to FOCUS degradation kinetics. In: Del Re AAM, Capri E, Fragoulis G and Trevisan M (Eds.). Proceedings of the XIII Symposium Pesticide Chemistry, Piacenza, 2007, p. 916-923.</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='va'>data</span> <span class='op'><-</span> <span class='fu'><a href='mkin_wide_to_long.html'>mkin_wide_to_long</a></span><span class='op'>(</span><span class='va'>schaefer07_complex_case</span>, time <span class='op'>=</span> <span class='st'>"time"</span><span class='op'>)</span> -<span class='va'>model</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"A1"</span>, <span class='st'>"B1"</span>, <span class='st'>"C1"</span><span class='op'>)</span>, sink <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span>, - A1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"A2"</span><span class='op'>)</span>, - B1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, - C1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, - A2 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> <span class='co'># \dontrun{</span> - <span class='va'>fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>model</span>, <span class='va'>data</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - <span class='fu'><a href='https://rdrr.io/r/graphics/plot.default.html'>plot</a></span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span> -</div><div class='img'><img src='schaefer07_complex_case-1.png' alt='' width='700' height='433' /></div><div class='input'> <span class='fu'><a href='endpoints.html'>endpoints</a></span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span> -</div><div class='output co'>#> $ff -#> parent_A1 parent_B1 parent_C1 parent_sink A1_A2 A1_sink -#> 0.3809620 0.1954667 0.4235713 0.0000000 0.4479619 0.5520381 -#> -#> $distimes -#> DT50 DT90 -#> parent 13.95078 46.34350 -#> A1 49.75342 165.27728 -#> B1 37.26908 123.80520 -#> C1 11.23131 37.30961 -#> A2 28.50624 94.69567 -#> </div><div class='input'> <span class='co'># }</span> - <span class='co'># Compare with the results obtained in the original publication</span> - <span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>schaefer07_complex_results</span><span class='op'>)</span> -</div><div class='output co'>#> compound parameter KinGUI ModelMaker deviation -#> 1 parent degradation rate 0.0496 0.0506 2.0 -#> 2 parent DT50 13.9900 13.6900 2.2 -#> 3 metabolite A1 formation fraction 0.3803 0.3696 2.9 -#> 4 metabolite A1 degradation rate 0.0139 0.0136 2.2 -#> 5 metabolite A1 DT50 49.9600 50.8900 1.8 -#> 6 metabolite B1 formation fraction 0.1866 0.1818 2.6 -#> 7 metabolite B1 degradation rate 0.0175 0.0172 1.7 -#> 8 metabolite B1 DT50 39.6100 40.2400 1.6 -#> 9 metabolite C1 formation fraction 0.4331 0.4486 3.5 -#> 10 metabolite C1 degradation rate 0.0638 0.0700 8.9 -#> 11 metabolite C1 DT50 10.8700 9.9000 9.8 -#> 12 metabolite A2 formation fraction 0.4529 0.4559 0.7 -#> 13 metabolite A2 degradation rate 0.0245 0.0244 0.4 -#> 14 metabolite A2 DT50 28.2400 28.4500 0.7</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="va">data</span> <span class="op"><-</span> <span class="fu"><a href="mkin_wide_to_long.html">mkin_wide_to_long</a></span><span class="op">(</span><span class="va">schaefer07_complex_case</span>, time <span class="op">=</span> <span class="st">"time"</span><span class="op">)</span></span> +<span class="r-in"><span class="va">model</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"A1"</span>, <span class="st">"B1"</span>, <span class="st">"C1"</span><span class="op">)</span>, sink <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span>,</span> +<span class="r-in"> A1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"A2"</span><span class="op">)</span>,</span> +<span class="r-in"> B1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> C1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> A2 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>, use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"> <span class="co"># \dontrun{</span></span> +<span class="r-in"> <span class="va">fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">model</span>, <span class="va">data</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/pkg/saemix/man/plot-SaemixObject-ANY-method.html" class="external-link">plot</a></span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></span> +<span class="r-plt img"><img src="schaefer07_complex_case-1.png" alt="" width="700" height="433"></span> +<span class="r-in"> <span class="fu"><a href="endpoints.html">endpoints</a></span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> $ff</span> +<span class="r-out co"><span class="r-pr">#></span> parent_A1 parent_B1 parent_C1 parent_sink A1_A2 A1_sink </span> +<span class="r-out co"><span class="r-pr">#></span> 0.3809620 0.1954667 0.4235713 0.0000000 0.4479619 0.5520381 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> $distimes</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90</span> +<span class="r-out co"><span class="r-pr">#></span> parent 13.95078 46.34350</span> +<span class="r-out co"><span class="r-pr">#></span> A1 49.75342 165.27728</span> +<span class="r-out co"><span class="r-pr">#></span> B1 37.26908 123.80520</span> +<span class="r-out co"><span class="r-pr">#></span> C1 11.23131 37.30961</span> +<span class="r-out co"><span class="r-pr">#></span> A2 28.50624 94.69567</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-in"> <span class="co"># }</span></span> +<span class="r-in"> <span class="co"># Compare with the results obtained in the original publication</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">schaefer07_complex_results</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> compound parameter KinGUI ModelMaker deviation</span> +<span class="r-out co"><span class="r-pr">#></span> 1 parent degradation rate 0.0496 0.0506 2.0</span> +<span class="r-out co"><span class="r-pr">#></span> 2 parent DT50 13.9900 13.6900 2.2</span> +<span class="r-out co"><span class="r-pr">#></span> 3 metabolite A1 formation fraction 0.3803 0.3696 2.9</span> +<span class="r-out co"><span class="r-pr">#></span> 4 metabolite A1 degradation rate 0.0139 0.0136 2.2</span> +<span class="r-out co"><span class="r-pr">#></span> 5 metabolite A1 DT50 49.9600 50.8900 1.8</span> +<span class="r-out co"><span class="r-pr">#></span> 6 metabolite B1 formation fraction 0.1866 0.1818 2.6</span> +<span class="r-out co"><span class="r-pr">#></span> 7 metabolite B1 degradation rate 0.0175 0.0172 1.7</span> +<span class="r-out co"><span class="r-pr">#></span> 8 metabolite B1 DT50 39.6100 40.2400 1.6</span> +<span class="r-out co"><span class="r-pr">#></span> 9 metabolite C1 formation fraction 0.4331 0.4486 3.5</span> +<span class="r-out co"><span class="r-pr">#></span> 10 metabolite C1 degradation rate 0.0638 0.0700 8.9</span> +<span class="r-out co"><span class="r-pr">#></span> 11 metabolite C1 DT50 10.8700 9.9000 9.8</span> +<span class="r-out co"><span class="r-pr">#></span> 12 metabolite A2 formation fraction 0.4529 0.4559 0.7</span> +<span class="r-out co"><span class="r-pr">#></span> 13 metabolite A2 degradation rate 0.0245 0.0244 0.4</span> +<span class="r-out co"><span class="r-pr">#></span> 14 metabolite A2 DT50 28.2400 28.4500 0.7</span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/sigma_twocomp-1.png b/docs/reference/sigma_twocomp-1.png Binary files differindex fddb86a7..0353b72c 100644 --- a/docs/reference/sigma_twocomp-1.png +++ b/docs/reference/sigma_twocomp-1.png diff --git a/docs/reference/sigma_twocomp.html b/docs/reference/sigma_twocomp.html index 1b4e45e4..63e23326 100644 --- a/docs/reference/sigma_twocomp.html +++ b/docs/reference/sigma_twocomp.html @@ -1,68 +1,13 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Two-component error model — sigma_twocomp • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Two-component error model — sigma_twocomp" /> -<meta property="og:description" content="Function describing the standard deviation of the measurement error in -dependence of the measured value \(y\):" /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Two-component error model — sigma_twocomp • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Two-component error model — sigma_twocomp"><meta property="og:description" content="Function describing the standard deviation of the measurement error in +dependence of the measured value \(y\):"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -73,13 +18,12 @@ dependence of the measured value \(y\):" /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -88,8 +32,7 @@ dependence of the measured value \(y\):" /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -99,6 +42,9 @@ dependence of the measured value \(y\):" /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -113,34 +59,27 @@ dependence of the measured value \(y\):" /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Two-component error model</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/sigma_twocomp.R'><code>R/sigma_twocomp.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/sigma_twocomp.R" class="external-link"><code>R/sigma_twocomp.R</code></a></small> <div class="hidden name"><code>sigma_twocomp.Rd</code></div> </div> @@ -149,40 +88,36 @@ dependence of the measured value \(y\):" /> dependence of the measured value \(y\):</p> </div> - <pre class="usage"><span class='fu'>sigma_twocomp</span><span class='op'>(</span><span class='va'>y</span>, <span class='va'>sigma_low</span>, <span class='va'>rsd_high</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>y</th> - <td><p>The magnitude of the observed value</p></td> - </tr> - <tr> - <th>sigma_low</th> - <td><p>The asymptotic minimum of the standard deviation for low -observed values</p></td> - </tr> - <tr> - <th>rsd_high</th> - <td><p>The coefficient describing the increase of the standard -deviation with the magnitude of the observed value</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">sigma_twocomp</span><span class="op">(</span><span class="va">y</span>, <span class="va">sigma_low</span>, <span class="va">rsd_high</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>y</dt> +<dd><p>The magnitude of the observed value</p></dd> +<dt>sigma_low</dt> +<dd><p>The asymptotic minimum of the standard deviation for low +observed values</p></dd> +<dt>rsd_high</dt> +<dd><p>The coefficient describing the increase of the standard +deviation with the magnitude of the observed value</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The standard deviation of the response variable.</p> - <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2> - + </div> + <div id="details"> + <h2>Details</h2> <p>$$\sigma = \sqrt{ \sigma_{low}^2 + y^2 * {rsd}_{high}^2}$$ sigma = sqrt(sigma_low^2 + y^2 * rsd_high^2)</p> <p>This is the error model used for example by Werner et al. (1978). The model proposed by Rocke and Lorenzato (1995) can be written in this form as well, but assumes approximate lognormal distribution of errors for high values of y.</p> - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - + </div> + <div id="references"> + <h2>References</h2> <p>Werner, Mario, Brooks, Samuel H., and Knott, Lancaster B. (1978) Additive, Multiplicative, and Mixed Analytical Errors. Clinical Chemistry 24(11), 1895-1898.</p> @@ -190,61 +125,62 @@ Additive, Multiplicative, and Mixed Analytical Errors. Clinical Chemistry measurement error in analytical chemistry. Technometrics 37(2), 176-184.</p> <p>Ranke J and Meinecke S (2019) Error Models for the Kinetic Evaluation of Chemical Degradation Data. <em>Environments</em> 6(12) 124 -doi: <a href='https://doi.org/10.3390/environments6120124'>10.3390/environments6120124</a> +doi: <a href="https://doi.org/10.3390/environments6120124" class="external-link">10.3390/environments6120124</a> .</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='va'>times</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>1</span>, <span class='fl'>3</span>, <span class='fl'>7</span>, <span class='fl'>14</span>, <span class='fl'>28</span>, <span class='fl'>60</span>, <span class='fl'>90</span>, <span class='fl'>120</span><span class='op'>)</span> -<span class='va'>d_pred</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/data.frame.html'>data.frame</a></span><span class='op'>(</span>time <span class='op'>=</span> <span class='va'>times</span>, parent <span class='op'>=</span> <span class='fl'>100</span> <span class='op'>*</span> <span class='fu'><a href='https://rdrr.io/r/base/Log.html'>exp</a></span><span class='op'>(</span><span class='op'>-</span> <span class='fl'>0.03</span> <span class='op'>*</span> <span class='va'>times</span><span class='op'>)</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/Random.html'>set.seed</a></span><span class='op'>(</span><span class='fl'>123456</span><span class='op'>)</span> -<span class='va'>d_syn</span> <span class='op'><-</span> <span class='fu'><a href='add_err.html'>add_err</a></span><span class='op'>(</span><span class='va'>d_pred</span>, <span class='kw'>function</span><span class='op'>(</span><span class='va'>y</span><span class='op'>)</span> <span class='fu'>sigma_twocomp</span><span class='op'>(</span><span class='va'>y</span>, <span class='fl'>1</span>, <span class='fl'>0.07</span><span class='op'>)</span>, - reps <span class='op'>=</span> <span class='fl'>2</span>, n <span class='op'>=</span> <span class='fl'>1</span><span class='op'>)</span><span class='op'>[[</span><span class='fl'>1</span><span class='op'>]</span><span class='op'>]</span> -<span class='va'>f_nls</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/nls.html'>nls</a></span><span class='op'>(</span><span class='va'>value</span> <span class='op'>~</span> <span class='fu'><a href='https://rdrr.io/r/stats/SSasymp.html'>SSasymp</a></span><span class='op'>(</span><span class='va'>time</span>, <span class='fl'>0</span>, <span class='va'>parent_0</span>, <span class='va'>lrc</span><span class='op'>)</span>, data <span class='op'>=</span> <span class='va'>d_syn</span>, - start <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>parent_0 <span class='op'>=</span> <span class='fl'>100</span>, lrc <span class='op'>=</span> <span class='op'>-</span><span class='fl'>3</span><span class='op'>)</span><span class='op'>)</span> -<span class='kw'><a href='https://rdrr.io/r/base/library.html'>library</a></span><span class='op'>(</span><span class='va'><a href='https://svn.r-project.org/R-packages/trunk/nlme/'>nlme</a></span><span class='op'>)</span> -<span class='va'>f_gnls</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/pkg/nlme/man/gnls.html'>gnls</a></span><span class='op'>(</span><span class='va'>value</span> <span class='op'>~</span> <span class='fu'><a href='https://rdrr.io/r/stats/SSasymp.html'>SSasymp</a></span><span class='op'>(</span><span class='va'>time</span>, <span class='fl'>0</span>, <span class='va'>parent_0</span>, <span class='va'>lrc</span><span class='op'>)</span>, - data <span class='op'>=</span> <span class='va'>d_syn</span>, na.action <span class='op'>=</span> <span class='va'>na.omit</span>, - start <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>parent_0 <span class='op'>=</span> <span class='fl'>100</span>, lrc <span class='op'>=</span> <span class='op'>-</span><span class='fl'>3</span><span class='op'>)</span><span class='op'>)</span> -<span class='kw'>if</span> <span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/length.html'>length</a></span><span class='op'>(</span><span class='fu'>findFunction</span><span class='op'>(</span><span class='st'>"varConstProp"</span><span class='op'>)</span><span class='op'>)</span> <span class='op'>></span> <span class='fl'>0</span><span class='op'>)</span> <span class='op'>{</span> - <span class='va'>f_gnls_tc</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/update.html'>update</a></span><span class='op'>(</span><span class='va'>f_gnls</span>, weights <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/pkg/nlme/man/varConstProp.html'>varConstProp</a></span><span class='op'>(</span><span class='op'>)</span><span class='op'>)</span> - <span class='va'>f_gnls_tc_sf</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/update.html'>update</a></span><span class='op'>(</span><span class='va'>f_gnls_tc</span>, control <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>sigma <span class='op'>=</span> <span class='fl'>1</span><span class='op'>)</span><span class='op'>)</span> -<span class='op'>}</span> -<span class='va'>f_mkin</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='va'>d_syn</span>, error_model <span class='op'>=</span> <span class='st'>"const"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='va'>f_mkin_tc</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='va'>d_syn</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'><a href='plot.mkinfit.html'>plot_res</a></span><span class='op'>(</span><span class='va'>f_mkin_tc</span>, standardized <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='img'><img src='sigma_twocomp-1.png' alt='' width='700' height='433' /></div><div class='input'><span class='fu'><a href='https://rdrr.io/r/stats/AIC.html'>AIC</a></span><span class='op'>(</span><span class='va'>f_nls</span>, <span class='va'>f_gnls</span>, <span class='va'>f_gnls_tc</span>, <span class='va'>f_gnls_tc_sf</span>, <span class='va'>f_mkin</span>, <span class='va'>f_mkin_tc</span><span class='op'>)</span> -</div><div class='output co'>#> df AIC -#> f_nls 3 114.4817 -#> f_gnls 3 114.4817 -#> f_gnls_tc 5 103.6447 -#> f_gnls_tc_sf 4 101.6447 -#> f_mkin 3 114.4817 -#> f_mkin_tc 4 101.6446</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="va">times</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">1</span>, <span class="fl">3</span>, <span class="fl">7</span>, <span class="fl">14</span>, <span class="fl">28</span>, <span class="fl">60</span>, <span class="fl">90</span>, <span class="fl">120</span><span class="op">)</span></span> +<span class="r-in"><span class="va">d_pred</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/data.frame.html" class="external-link">data.frame</a></span><span class="op">(</span>time <span class="op">=</span> <span class="va">times</span>, parent <span class="op">=</span> <span class="fl">100</span> <span class="op">*</span> <span class="fu"><a href="https://rdrr.io/r/base/Log.html" class="external-link">exp</a></span><span class="op">(</span><span class="op">-</span> <span class="fl">0.03</span> <span class="op">*</span> <span class="va">times</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/Random.html" class="external-link">set.seed</a></span><span class="op">(</span><span class="fl">123456</span><span class="op">)</span></span> +<span class="r-in"><span class="va">d_syn</span> <span class="op"><-</span> <span class="fu"><a href="add_err.html">add_err</a></span><span class="op">(</span><span class="va">d_pred</span>, <span class="kw">function</span><span class="op">(</span><span class="va">y</span><span class="op">)</span> <span class="fu">sigma_twocomp</span><span class="op">(</span><span class="va">y</span>, <span class="fl">1</span>, <span class="fl">0.07</span><span class="op">)</span>,</span> +<span class="r-in"> reps <span class="op">=</span> <span class="fl">2</span>, n <span class="op">=</span> <span class="fl">1</span><span class="op">)</span><span class="op">[[</span><span class="fl">1</span><span class="op">]</span><span class="op">]</span></span> +<span class="r-in"><span class="va">f_nls</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/nls.html" class="external-link">nls</a></span><span class="op">(</span><span class="va">value</span> <span class="op">~</span> <span class="fu"><a href="https://rdrr.io/r/stats/SSasymp.html" class="external-link">SSasymp</a></span><span class="op">(</span><span class="va">time</span>, <span class="fl">0</span>, <span class="va">parent_0</span>, <span class="va">lrc</span><span class="op">)</span>, data <span class="op">=</span> <span class="va">d_syn</span>,</span> +<span class="r-in"> start <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>parent_0 <span class="op">=</span> <span class="fl">100</span>, lrc <span class="op">=</span> <span class="op">-</span><span class="fl">3</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="kw"><a href="https://rdrr.io/r/base/library.html" class="external-link">library</a></span><span class="op">(</span><span class="va"><a href="https://svn.r-project.org/R-packages/trunk/nlme/" class="external-link">nlme</a></span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_gnls</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlme/man/gnls.html" class="external-link">gnls</a></span><span class="op">(</span><span class="va">value</span> <span class="op">~</span> <span class="fu"><a href="https://rdrr.io/r/stats/SSasymp.html" class="external-link">SSasymp</a></span><span class="op">(</span><span class="va">time</span>, <span class="fl">0</span>, <span class="va">parent_0</span>, <span class="va">lrc</span><span class="op">)</span>,</span> +<span class="r-in"> data <span class="op">=</span> <span class="va">d_syn</span>, na.action <span class="op">=</span> <span class="va">na.omit</span>,</span> +<span class="r-in"> start <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>parent_0 <span class="op">=</span> <span class="fl">100</span>, lrc <span class="op">=</span> <span class="op">-</span><span class="fl">3</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="kw">if</span> <span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/length.html" class="external-link">length</a></span><span class="op">(</span><span class="fu">findFunction</span><span class="op">(</span><span class="st">"varConstProp"</span><span class="op">)</span><span class="op">)</span> <span class="op">></span> <span class="fl">0</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="va">f_gnls_tc</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/update.html" class="external-link">update</a></span><span class="op">(</span><span class="va">f_gnls</span>, weights <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/pkg/nlme/man/varConstProp.html" class="external-link">varConstProp</a></span><span class="op">(</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"> <span class="va">f_gnls_tc_sf</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/update.html" class="external-link">update</a></span><span class="op">(</span><span class="va">f_gnls_tc</span>, control <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>sigma <span class="op">=</span> <span class="fl">1</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="op">}</span></span> +<span class="r-in"><span class="va">f_mkin</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="va">d_syn</span>, error_model <span class="op">=</span> <span class="st">"const"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_mkin_tc</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="va">d_syn</span>, error_model <span class="op">=</span> <span class="st">"tc"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="plot.mkinfit.html">plot_res</a></span><span class="op">(</span><span class="va">f_mkin_tc</span>, standardized <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-plt img"><img src="sigma_twocomp-1.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">AIC</a></span><span class="op">(</span><span class="va">f_nls</span>, <span class="va">f_gnls</span>, <span class="va">f_gnls_tc</span>, <span class="va">f_gnls_tc_sf</span>, <span class="va">f_mkin</span>, <span class="va">f_mkin_tc</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> df AIC</span> +<span class="r-out co"><span class="r-pr">#></span> f_nls 3 114.4817</span> +<span class="r-out co"><span class="r-pr">#></span> f_gnls 3 114.4817</span> +<span class="r-out co"><span class="r-pr">#></span> f_gnls_tc 5 103.6447</span> +<span class="r-out co"><span class="r-pr">#></span> f_gnls_tc_sf 4 101.6447</span> +<span class="r-out co"><span class="r-pr">#></span> f_mkin 3 114.4817</span> +<span class="r-out co"><span class="r-pr">#></span> f_mkin_tc 4 101.6446</span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/summary.mkinfit.html b/docs/reference/summary.mkinfit.html index 67a50216..b4d25f4f 100644 --- a/docs/reference/summary.mkinfit.html +++ b/docs/reference/summary.mkinfit.html @@ -1,71 +1,16 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Summary method for class "mkinfit" — summary.mkinfit • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Summary method for class "mkinfit" — summary.mkinfit" /> -<meta property="og:description" content="Lists model equations, initial parameter values, optimised parameters with +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Summary method for class "mkinfit" — summary.mkinfit • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Summary method for class " mkinfit summary.mkinfit><meta property="og:description" content="Lists model equations, initial parameter values, optimised parameters with some uncertainty statistics, the chi2 error levels calculated according to FOCUS guidance (2006) as defined therein, formation fractions, DT50 values and optionally the data, consisting of observed, predicted and residual -values." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +values."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -76,13 +21,12 @@ values." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -91,8 +35,7 @@ values." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -102,6 +45,9 @@ values." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -116,34 +62,27 @@ values." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Summary method for class "mkinfit"</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/summary.mkinfit.R'><code>R/summary.mkinfit.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/summary.mkinfit.R" class="external-link"><code>R/summary.mkinfit.R</code></a></small> <div class="hidden name"><code>summary.mkinfit.Rd</code></div> </div> @@ -155,187 +94,188 @@ and optionally the data, consisting of observed, predicted and residual values.</p> </div> - <pre class="usage"><span class='co'># S3 method for mkinfit</span> -<span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>object</span>, data <span class='op'>=</span> <span class='cn'>TRUE</span>, distimes <span class='op'>=</span> <span class='cn'>TRUE</span>, alpha <span class='op'>=</span> <span class='fl'>0.05</span>, <span class='va'>...</span><span class='op'>)</span> - -<span class='co'># S3 method for summary.mkinfit</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>x</span>, digits <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/Extremes.html'>max</a></span><span class='op'>(</span><span class='fl'>3</span>, <span class='fu'><a href='https://rdrr.io/r/base/options.html'>getOption</a></span><span class='op'>(</span><span class='st'>"digits"</span><span class='op'>)</span> <span class='op'>-</span> <span class='fl'>3</span><span class='op'>)</span>, <span class='va'>...</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>an object of class <code><a href='mkinfit.html'>mkinfit</a></code>.</p></td> - </tr> - <tr> - <th>data</th> - <td><p>logical, indicating whether the data should be included in the -summary.</p></td> - </tr> - <tr> - <th>distimes</th> - <td><p>logical, indicating whether DT50 and DT90 values should be -included.</p></td> - </tr> - <tr> - <th>alpha</th> - <td><p>error level for confidence interval estimation from t -distribution</p></td> - </tr> - <tr> - <th>...</th> - <td><p>optional arguments passed to methods like <code>print</code>.</p></td> - </tr> - <tr> - <th>x</th> - <td><p>an object of class <code>summary.mkinfit</code>.</p></td> - </tr> - <tr> - <th>digits</th> - <td><p>Number of digits to use for printing</p></td> - </tr> - </table> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for mkinfit</span> +<span class="fu"><a href="https://rdrr.io/pkg/saemix/man/summary-methods.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">object</span>, data <span class="op">=</span> <span class="cn">TRUE</span>, distimes <span class="op">=</span> <span class="cn">TRUE</span>, alpha <span class="op">=</span> <span class="fl">0.05</span>, <span class="va">...</span><span class="op">)</span> - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> +<span class="co"># S3 method for summary.mkinfit</span> +<span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">x</span>, digits <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/Extremes.html" class="external-link">max</a></span><span class="op">(</span><span class="fl">3</span>, <span class="fu"><a href="https://rdrr.io/r/base/options.html" class="external-link">getOption</a></span><span class="op">(</span><span class="st">"digits"</span><span class="op">)</span> <span class="op">-</span> <span class="fl">3</span><span class="op">)</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>an object of class <code><a href="mkinfit.html">mkinfit</a></code>.</p></dd> +<dt>data</dt> +<dd><p>logical, indicating whether the data should be included in the +summary.</p></dd> +<dt>distimes</dt> +<dd><p>logical, indicating whether DT50 and DT90 values should be +included.</p></dd> +<dt>alpha</dt> +<dd><p>error level for confidence interval estimation from t +distribution</p></dd> +<dt>...</dt> +<dd><p>optional arguments passed to methods like <code>print</code>.</p></dd> +<dt>x</dt> +<dd><p>an object of class <code>summary.mkinfit</code>.</p></dd> +<dt>digits</dt> +<dd><p>Number of digits to use for printing</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>The summary function returns a list with components, among others</p> -<dt>version, Rversion</dt><dd><p>The mkin and R versions used</p></dd> -<dt>date.fit, date.summary</dt><dd><p>The dates where the fit and the summary were +<dl><dt>version, Rversion</dt> +<dd><p>The mkin and R versions used</p></dd> +<dt>date.fit, date.summary</dt> +<dd><p>The dates where the fit and the summary were produced</p></dd> -<dt>diffs</dt><dd><p>The differential equations used in the model</p></dd> -<dt>use_of_ff</dt><dd><p>Was maximum or minimum use made of formation fractions</p></dd> -<dt>bpar</dt><dd><p>Optimised and backtransformed +<dt>diffs</dt> +<dd><p>The differential equations used in the model</p></dd> +<dt>use_of_ff</dt> +<dd><p>Was maximum or minimum use made of formation fractions</p></dd> +<dt>bpar</dt> +<dd><p>Optimised and backtransformed parameters</p></dd> -<dt>data</dt><dd><p>The data (see Description above).</p></dd> -<dt>start</dt><dd><p>The starting values and bounds, if applicable, for optimised +<dt>data</dt> +<dd><p>The data (see Description above).</p></dd> +<dt>start</dt> +<dd><p>The starting values and bounds, if applicable, for optimised parameters.</p></dd> -<dt>fixed</dt><dd><p>The values of fixed parameters.</p></dd> -<dt>errmin </dt><dd><p>The chi2 error levels for +<dt>fixed</dt> +<dd><p>The values of fixed parameters.</p></dd> +<dt>errmin </dt> +<dd><p>The chi2 error levels for each observed variable.</p></dd> -<dt>bparms.ode</dt><dd><p>All backtransformed ODE +<dt>bparms.ode</dt> +<dd><p>All backtransformed ODE parameters, for use as starting parameters for related models.</p></dd> -<dt>errparms</dt><dd><p>Error model parameters.</p></dd> -<dt>ff</dt><dd><p>The estimated formation fractions derived from the fitted +<dt>errparms</dt> +<dd><p>Error model parameters.</p></dd> +<dt>ff</dt> +<dd><p>The estimated formation fractions derived from the fitted model.</p></dd> -<dt>distimes</dt><dd><p>The DT50 and DT90 values for each observed variable.</p></dd> -<dt>SFORB</dt><dd><p>If applicable, eigenvalues of SFORB components of the model.</p></dd> -The print method is called for its side effect, i.e. printing the summary. - - <h2 class="hasAnchor" id="references"><a class="anchor" href="#references"></a>References</h2> - - <p>FOCUS (2006) “Guidance Document on Estimating Persistence +<dt>distimes</dt> +<dd><p>The DT50 and DT90 values for each observed variable.</p></dd> +<dt>SFORB</dt> +<dd><p>If applicable, eigenvalues of SFORB components of the model.</p></dd> +</dl><p>The print method is called for its side effect, i.e. printing the summary.</p> + </div> + <div id="references"> + <h2>References</h2> + <p>FOCUS (2006) “Guidance Document on Estimating Persistence and Degradation Kinetics from Environmental Fate Studies on Pesticides in -EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, +EU Registration” Report of the FOCUS Work Group on Degradation Kinetics, EC Document Reference Sanco/10058/2005 version 2.0, 434 pp, -<a href='http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics'>http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - +<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p> + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> - <span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span>, <span class='va'>FOCUS_2006_A</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> mkin version used for fitting: 1.0.3 -#> R version used for fitting: 4.0.3 -#> Date of fit: Mon Feb 15 13:46:11 2021 -#> Date of summary: Mon Feb 15 13:46:11 2021 -#> -#> Equations: -#> d_parent/dt = - k_parent * parent -#> -#> Model predictions using solution type analytical -#> -#> Fitted using 131 model solutions performed in 0.029 s -#> -#> Error model: Constant variance -#> -#> Error model algorithm: OLS -#> -#> Starting values for parameters to be optimised: -#> value type -#> parent_0 101.24 state -#> k_parent 0.10 deparm -#> -#> Starting values for the transformed parameters actually optimised: -#> value lower upper -#> parent_0 101.240000 -Inf Inf -#> log_k_parent -2.302585 -Inf Inf -#> -#> Fixed parameter values: -#> None -#> -#> Results: -#> -#> AIC BIC logLik -#> 55.28197 55.5203 -24.64099 -#> -#> Optimised, transformed parameters with symmetric confidence intervals: -#> Estimate Std. Error Lower Upper -#> parent_0 109.200 3.70400 99.630 118.700 -#> log_k_parent -3.291 0.09176 -3.527 -3.055 -#> sigma 5.266 1.31600 1.882 8.649 -#> -#> Parameter correlation: -#> parent_0 log_k_parent sigma -#> parent_0 1.000e+00 5.428e-01 1.642e-07 -#> log_k_parent 5.428e-01 1.000e+00 2.507e-07 -#> sigma 1.642e-07 2.507e-07 1.000e+00 -#> -#> Backtransformed parameters: -#> Confidence intervals for internally transformed parameters are asymmetric. -#> t-test (unrealistically) based on the assumption of normal distribution -#> for estimators of untransformed parameters. -#> Estimate t value Pr(>t) Lower Upper -#> parent_0 109.20000 29.47 4.218e-07 99.6300 118.70000 -#> k_parent 0.03722 10.90 5.650e-05 0.0294 0.04712 -#> sigma 5.26600 4.00 5.162e-03 1.8820 8.64900 -#> -#> FOCUS Chi2 error levels in percent: -#> err.min n.optim df -#> All data 8.385 2 6 -#> parent 8.385 2 6 -#> -#> Estimated disappearance times: -#> DT50 DT90 -#> parent 18.62 61.87 -#> -#> Data: -#> time variable observed predicted residual -#> 0 parent 101.24 109.153 -7.9132 -#> 3 parent 99.27 97.622 1.6484 -#> 7 parent 90.11 84.119 5.9913 -#> 14 parent 72.19 64.826 7.3641 -#> 30 parent 29.71 35.738 -6.0283 -#> 62 parent 5.98 10.862 -4.8818 -#> 90 parent 1.54 3.831 -2.2911 -#> 118 parent 0.39 1.351 -0.9613</div><div class='input'> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/pkg/saemix/man/summary-methods.html" class="external-link">summary</a></span><span class="op">(</span><span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span>, <span class="va">FOCUS_2006_A</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> mkin version used for fitting: 1.1.0 </span> +<span class="r-out co"><span class="r-pr">#></span> R version used for fitting: 4.1.2 </span> +<span class="r-out co"><span class="r-pr">#></span> Date of fit: Wed Mar 2 13:42:12 2022 </span> +<span class="r-out co"><span class="r-pr">#></span> Date of summary: Wed Mar 2 13:42:12 2022 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Equations:</span> +<span class="r-out co"><span class="r-pr">#></span> d_parent/dt = - k_parent * parent</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model predictions using solution type analytical </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fitted using 131 model solutions performed in 0.029 s</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Error model: Constant variance </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Error model algorithm: OLS </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Starting values for parameters to be optimised:</span> +<span class="r-out co"><span class="r-pr">#></span> value type</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 101.24 state</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.10 deparm</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Starting values for the transformed parameters actually optimised:</span> +<span class="r-out co"><span class="r-pr">#></span> value lower upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 101.240000 -Inf Inf</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent -2.302585 -Inf Inf</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fixed parameter values:</span> +<span class="r-out co"><span class="r-pr">#></span> None</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Results:</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> AIC BIC logLik</span> +<span class="r-out co"><span class="r-pr">#></span> 55.28197 55.5203 -24.64099</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Optimised, transformed parameters with symmetric confidence intervals:</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Std. Error Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 109.200 3.70400 99.630 118.700</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent -3.291 0.09176 -3.527 -3.055</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 5.266 1.31600 1.882 8.649</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Parameter correlation:</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_k_parent sigma</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 1.000e+00 5.428e-01 1.642e-07</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent 5.428e-01 1.000e+00 2.507e-07</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 1.642e-07 2.507e-07 1.000e+00</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Backtransformed parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> Confidence intervals for internally transformed parameters are asymmetric.</span> +<span class="r-out co"><span class="r-pr">#></span> t-test (unrealistically) based on the assumption of normal distribution</span> +<span class="r-out co"><span class="r-pr">#></span> for estimators of untransformed parameters.</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate t value Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 109.20000 29.47 4.218e-07 99.6300 118.70000</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.03722 10.90 5.650e-05 0.0294 0.04712</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 5.26600 4.00 5.162e-03 1.8820 8.64900</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> FOCUS Chi2 error levels in percent:</span> +<span class="r-out co"><span class="r-pr">#></span> err.min n.optim df</span> +<span class="r-out co"><span class="r-pr">#></span> All data 8.385 2 6</span> +<span class="r-out co"><span class="r-pr">#></span> parent 8.385 2 6</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Estimated disappearance times:</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90</span> +<span class="r-out co"><span class="r-pr">#></span> parent 18.62 61.87</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Data:</span> +<span class="r-out co"><span class="r-pr">#></span> time variable observed predicted residual</span> +<span class="r-out co"><span class="r-pr">#></span> 0 parent 101.24 109.153 -7.9132</span> +<span class="r-out co"><span class="r-pr">#></span> 3 parent 99.27 97.622 1.6484</span> +<span class="r-out co"><span class="r-pr">#></span> 7 parent 90.11 84.119 5.9913</span> +<span class="r-out co"><span class="r-pr">#></span> 14 parent 72.19 64.826 7.3641</span> +<span class="r-out co"><span class="r-pr">#></span> 30 parent 29.71 35.738 -6.0283</span> +<span class="r-out co"><span class="r-pr">#></span> 62 parent 5.98 10.862 -4.8818</span> +<span class="r-out co"><span class="r-pr">#></span> 90 parent 1.54 3.831 -2.2911</span> +<span class="r-out co"><span class="r-pr">#></span> 118 parent 0.39 1.351 -0.9613</span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/summary.nlme.mmkin.html b/docs/reference/summary.nlme.mmkin.html index 8df9011d..2bc50dac 100644 --- a/docs/reference/summary.nlme.mmkin.html +++ b/docs/reference/summary.nlme.mmkin.html @@ -1,71 +1,16 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Summary method for class "nlme.mmkin" — summary.nlme.mmkin • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Summary method for class "nlme.mmkin" — summary.nlme.mmkin" /> -<meta property="og:description" content="Lists model equations, initial parameter values, optimised parameters +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Summary method for class "nlme.mmkin" — summary.nlme.mmkin • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Summary method for class " nlme.mmkin summary.nlme.mmkin><meta property="og:description" content="Lists model equations, initial parameter values, optimised parameters for fixed effects (population), random effects (deviations from the population mean) and residual error model, as well as the resulting endpoints such as formation fractions and DT50 values. Optionally -(default is FALSE), the data are listed in full." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +(default is FALSE), the data are listed in full."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -76,13 +21,12 @@ endpoints such as formation fractions and DT50 values. Optionally </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -91,8 +35,7 @@ endpoints such as formation fractions and DT50 values. Optionally <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -102,6 +45,9 @@ endpoints such as formation fractions and DT50 values. Optionally <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -116,34 +62,27 @@ endpoints such as formation fractions and DT50 values. Optionally <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Summary method for class "nlme.mmkin"</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/summary.nlme.mmkin.R'><code>R/summary.nlme.mmkin.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/summary.nlme.mmkin.R" class="external-link"><code>R/summary.nlme.mmkin.R</code></a></small> <div class="hidden name"><code>summary.nlme.mmkin.Rd</code></div> </div> @@ -155,295 +94,288 @@ endpoints such as formation fractions and DT50 values. Optionally (default is FALSE), the data are listed in full.</p> </div> - <pre class="usage"><span class='co'># S3 method for nlme.mmkin</span> -<span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span> - <span class='va'>object</span>, - data <span class='op'>=</span> <span class='cn'>FALSE</span>, - verbose <span class='op'>=</span> <span class='cn'>FALSE</span>, - distimes <span class='op'>=</span> <span class='cn'>TRUE</span>, - alpha <span class='op'>=</span> <span class='fl'>0.05</span>, - <span class='va'>...</span> -<span class='op'>)</span> - -<span class='co'># S3 method for summary.nlme.mmkin</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>x</span>, digits <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/Extremes.html'>max</a></span><span class='op'>(</span><span class='fl'>3</span>, <span class='fu'><a href='https://rdrr.io/r/base/options.html'>getOption</a></span><span class='op'>(</span><span class='st'>"digits"</span><span class='op'>)</span> <span class='op'>-</span> <span class='fl'>3</span><span class='op'>)</span>, verbose <span class='op'>=</span> <span class='va'>x</span><span class='op'>$</span><span class='va'>verbose</span>, <span class='va'>...</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>an object of class <a href='nlme.mmkin.html'>nlme.mmkin</a></p></td> - </tr> - <tr> - <th>data</th> - <td><p>logical, indicating whether the full data should be included in -the summary.</p></td> - </tr> - <tr> - <th>verbose</th> - <td><p>Should the summary be verbose?</p></td> - </tr> - <tr> - <th>distimes</th> - <td><p>logical, indicating whether DT50 and DT90 values should be -included.</p></td> - </tr> - <tr> - <th>alpha</th> - <td><p>error level for confidence interval estimation from the t -distribution</p></td> - </tr> - <tr> - <th>...</th> - <td><p>optional arguments passed to methods like <code>print</code>.</p></td> - </tr> - <tr> - <th>x</th> - <td><p>an object of class summary.nlme.mmkin</p></td> - </tr> - <tr> - <th>digits</th> - <td><p>Number of digits to use for printing</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for nlme.mmkin</span> +<span class="fu"><a href="https://rdrr.io/pkg/saemix/man/summary-methods.html" class="external-link">summary</a></span><span class="op">(</span> + <span class="va">object</span>, + data <span class="op">=</span> <span class="cn">FALSE</span>, + verbose <span class="op">=</span> <span class="cn">FALSE</span>, + distimes <span class="op">=</span> <span class="cn">TRUE</span>, + alpha <span class="op">=</span> <span class="fl">0.05</span>, + <span class="va">...</span> +<span class="op">)</span> + +<span class="co"># S3 method for summary.nlme.mmkin</span> +<span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">x</span>, digits <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/Extremes.html" class="external-link">max</a></span><span class="op">(</span><span class="fl">3</span>, <span class="fu"><a href="https://rdrr.io/r/base/options.html" class="external-link">getOption</a></span><span class="op">(</span><span class="st">"digits"</span><span class="op">)</span> <span class="op">-</span> <span class="fl">3</span><span class="op">)</span>, verbose <span class="op">=</span> <span class="va">x</span><span class="op">$</span><span class="va">verbose</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> - <p>The summary function returns a list based on the <a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme</a> object + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>an object of class <a href="nlme.mmkin.html">nlme.mmkin</a></p></dd> +<dt>data</dt> +<dd><p>logical, indicating whether the full data should be included in +the summary.</p></dd> +<dt>verbose</dt> +<dd><p>Should the summary be verbose?</p></dd> +<dt>distimes</dt> +<dd><p>logical, indicating whether DT50 and DT90 values should be +included.</p></dd> +<dt>alpha</dt> +<dd><p>error level for confidence interval estimation from the t +distribution</p></dd> +<dt>...</dt> +<dd><p>optional arguments passed to methods like <code>print</code>.</p></dd> +<dt>x</dt> +<dd><p>an object of class summary.nlme.mmkin</p></dd> +<dt>digits</dt> +<dd><p>Number of digits to use for printing</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>The summary function returns a list based on the <a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a> object obtained in the fit, with at least the following additional components</p> -<dt>nlmeversion, mkinversion, Rversion</dt><dd><p>The nlme, mkin and R versions used</p></dd> -<dt>date.fit, date.summary</dt><dd><p>The dates where the fit and the summary were +<dl><dt>nlmeversion, mkinversion, Rversion</dt> +<dd><p>The nlme, mkin and R versions used</p></dd> +<dt>date.fit, date.summary</dt> +<dd><p>The dates where the fit and the summary were produced</p></dd> -<dt>diffs</dt><dd><p>The differential equations used in the degradation model</p></dd> -<dt>use_of_ff</dt><dd><p>Was maximum or minimum use made of formation fractions</p></dd> -<dt>data</dt><dd><p>The data</p></dd> -<dt>confint_trans</dt><dd><p>Transformed parameters as used in the optimisation, with confidence intervals</p></dd> -<dt>confint_back</dt><dd><p>Backtransformed parameters, with confidence intervals if available</p></dd> -<dt>ff</dt><dd><p>The estimated formation fractions derived from the fitted +<dt>diffs</dt> +<dd><p>The differential equations used in the degradation model</p></dd> +<dt>use_of_ff</dt> +<dd><p>Was maximum or minimum use made of formation fractions</p></dd> +<dt>data</dt> +<dd><p>The data</p></dd> +<dt>confint_trans</dt> +<dd><p>Transformed parameters as used in the optimisation, with confidence intervals</p></dd> +<dt>confint_back</dt> +<dd><p>Backtransformed parameters, with confidence intervals if available</p></dd> +<dt>ff</dt> +<dd><p>The estimated formation fractions derived from the fitted model.</p></dd> -<dt>distimes</dt><dd><p>The DT50 and DT90 values for each observed variable.</p></dd> -<dt>SFORB</dt><dd><p>If applicable, eigenvalues of SFORB components of the model.</p></dd> -The print method is called for its side effect, i.e. printing the summary. - - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - +<dt>distimes</dt> +<dd><p>The DT50 and DT90 values for each observed variable.</p></dd> +<dt>SFORB</dt> +<dd><p>If applicable, eigenvalues of SFORB components of the model.</p></dd> +</dl><p>The print method is called for its side effect, i.e. printing the summary.</p> + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke for the mkin specific parts José Pinheiro and Douglas Bates for the components inherited from nlme</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='co'># Generate five datasets following SFO kinetics</span> -<span class='va'>sampling_times</span> <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>1</span>, <span class='fl'>3</span>, <span class='fl'>7</span>, <span class='fl'>14</span>, <span class='fl'>28</span>, <span class='fl'>60</span>, <span class='fl'>90</span>, <span class='fl'>120</span><span class='op'>)</span> -<span class='va'>dt50_sfo_in_pop</span> <span class='op'><-</span> <span class='fl'>50</span> -<span class='va'>k_in_pop</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/Log.html'>log</a></span><span class='op'>(</span><span class='fl'>2</span><span class='op'>)</span> <span class='op'>/</span> <span class='va'>dt50_sfo_in_pop</span> -<span class='fu'><a href='https://rdrr.io/r/base/Random.html'>set.seed</a></span><span class='op'>(</span><span class='fl'>1234</span><span class='op'>)</span> -<span class='va'>k_in</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/Lognormal.html'>rlnorm</a></span><span class='op'>(</span><span class='fl'>5</span>, <span class='fu'><a href='https://rdrr.io/r/base/Log.html'>log</a></span><span class='op'>(</span><span class='va'>k_in_pop</span><span class='op'>)</span>, <span class='fl'>0.5</span><span class='op'>)</span> -<span class='va'>SFO</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span><span class='op'>)</span> - -<span class='va'>pred_sfo</span> <span class='op'><-</span> <span class='kw'>function</span><span class='op'>(</span><span class='va'>k</span><span class='op'>)</span> <span class='op'>{</span> - <span class='fu'><a href='mkinpredict.html'>mkinpredict</a></span><span class='op'>(</span><span class='va'>SFO</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_parent <span class='op'>=</span> <span class='va'>k</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>100</span><span class='op'>)</span>, - <span class='va'>sampling_times</span><span class='op'>)</span> -<span class='op'>}</span> - -<span class='va'>ds_sfo_mean</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/lapply.html'>lapply</a></span><span class='op'>(</span><span class='va'>k_in</span>, <span class='va'>pred_sfo</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/names.html'>names</a></span><span class='op'>(</span><span class='va'>ds_sfo_mean</span><span class='op'>)</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/paste.html'>paste</a></span><span class='op'>(</span><span class='st'>"ds"</span>, <span class='fl'>1</span><span class='op'>:</span><span class='fl'>5</span><span class='op'>)</span> - -<span class='fu'><a href='https://rdrr.io/r/base/Random.html'>set.seed</a></span><span class='op'>(</span><span class='fl'>12345</span><span class='op'>)</span> -<span class='va'>ds_sfo_syn</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/lapply.html'>lapply</a></span><span class='op'>(</span><span class='va'>ds_sfo_mean</span>, <span class='kw'>function</span><span class='op'>(</span><span class='va'>ds</span><span class='op'>)</span> <span class='op'>{</span> - <span class='fu'><a href='add_err.html'>add_err</a></span><span class='op'>(</span><span class='va'>ds</span>, - sdfunc <span class='op'>=</span> <span class='kw'>function</span><span class='op'>(</span><span class='va'>value</span><span class='op'>)</span> <span class='fu'><a href='https://rdrr.io/r/base/MathFun.html'>sqrt</a></span><span class='op'>(</span><span class='fl'>1</span><span class='op'>^</span><span class='fl'>2</span> <span class='op'>+</span> <span class='va'>value</span><span class='op'>^</span><span class='fl'>2</span> <span class='op'>*</span> <span class='fl'>0.07</span><span class='op'>^</span><span class='fl'>2</span><span class='op'>)</span>, - n <span class='op'>=</span> <span class='fl'>1</span><span class='op'>)</span><span class='op'>[[</span><span class='fl'>1</span><span class='op'>]</span><span class='op'>]</span> -<span class='op'>}</span><span class='op'>)</span> - -<span class='co'># Evaluate using mmkin and nlme</span> -<span class='kw'><a href='https://rdrr.io/r/base/library.html'>library</a></span><span class='op'>(</span><span class='va'><a href='https://svn.r-project.org/R-packages/trunk/nlme/'>nlme</a></span><span class='op'>)</span> -<span class='va'>f_mmkin</span> <span class='op'><-</span> <span class='fu'><a href='mmkin.html'>mmkin</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='va'>ds_sfo_syn</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span>, cores <span class='op'>=</span> <span class='fl'>1</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='warning'>Warning: Optimisation did not converge:</span> -#> <span class='warning'>iteration limit reached without convergence (10)</span></div><div class='input'><span class='va'>f_nlme</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/pkg/nlme/man/nlme.html'>nlme</a></span><span class='op'>(</span><span class='va'>f_mmkin</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='warning'>Warning: Iteration 4, LME step: nlminb() did not converge (code = 1). PORT message: false convergence (8)</span></div><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>f_nlme</span>, data <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> nlme version used for fitting: 3.1.152 -#> mkin version used for pre-fitting: 1.0.4 -#> R version used for fitting: 4.0.4 -#> Date of fit: Wed Mar 31 19:18:24 2021 -#> Date of summary: Wed Mar 31 19:18:24 2021 -#> -#> Equations: -#> d_parent/dt = - k_parent * parent -#> -#> Data: -#> 90 observations of 1 variable(s) grouped in 5 datasets -#> -#> Model predictions using solution type analytical -#> -#> Fitted in 0.537 s using 4 iterations -#> -#> Variance model: Two-component variance function -#> -#> Mean of starting values for individual parameters: -#> parent_0 log_k_parent -#> 101.569 -4.454 -#> -#> Fixed degradation parameter values: -#> None -#> -#> Results: -#> -#> AIC BIC logLik -#> 584.5 599.5 -286.2 -#> -#> Optimised, transformed parameters with symmetric confidence intervals: -#> lower est. upper -#> parent_0 99.371 101.592 103.814 -#> log_k_parent -4.973 -4.449 -3.926 -#> -#> Correlation: -#> prnt_0 -#> log_k_parent 0.051 -#> -#> Random effects: -#> Formula: list(parent_0 ~ 1, log_k_parent ~ 1) -#> Level: ds -#> Structure: Diagonal -#> parent_0 log_k_parent Residual -#> StdDev: 6.924e-05 0.5863 1 -#> -#> Variance function: -#> Structure: Constant plus proportion of variance covariate -#> Formula: ~fitted(.) -#> Parameter estimates: -#> const prop -#> 0.0001208853 0.0789968036 -#> -#> Backtransformed parameters with asymmetric confidence intervals: -#> lower est. upper -#> parent_0 99.370882 101.59243 103.81398 -#> k_parent 0.006923 0.01168 0.01972 -#> -#> Estimated disappearance times: -#> DT50 DT90 -#> parent 59.32 197.1 -#> -#> Data: -#> ds name time observed predicted residual std standardized -#> ds 1 parent 0 104.1 101.592 2.50757 8.0255 0.312451 -#> ds 1 parent 0 105.0 101.592 3.40757 8.0255 0.424594 -#> ds 1 parent 1 98.5 100.796 -2.29571 7.9625 -0.288313 -#> ds 1 parent 1 96.1 100.796 -4.69571 7.9625 -0.589725 -#> ds 1 parent 3 101.9 99.221 2.67904 7.8381 0.341796 -#> ds 1 parent 3 85.2 99.221 -14.02096 7.8381 -1.788812 -#> ds 1 parent 7 99.1 96.145 2.95512 7.5951 0.389081 -#> ds 1 parent 7 93.0 96.145 -3.14488 7.5951 -0.414065 -#> ds 1 parent 14 88.1 90.989 -2.88944 7.1879 -0.401987 -#> ds 1 parent 14 84.1 90.989 -6.88944 7.1879 -0.958480 -#> ds 1 parent 28 80.2 81.493 -1.29305 6.4377 -0.200857 -#> ds 1 parent 28 91.3 81.493 9.80695 6.4377 1.523364 -#> ds 1 parent 60 65.1 63.344 1.75642 5.0039 0.351008 -#> ds 1 parent 60 65.8 63.344 2.45642 5.0039 0.490898 -#> ds 1 parent 90 47.8 50.018 -2.21764 3.9512 -0.561252 -#> ds 1 parent 90 53.5 50.018 3.48236 3.9512 0.881335 -#> ds 1 parent 120 37.6 39.495 -1.89515 3.1200 -0.607423 -#> ds 1 parent 120 39.3 39.495 -0.19515 3.1200 -0.062549 -#> ds 2 parent 0 107.9 101.592 6.30757 8.0255 0.785943 -#> ds 2 parent 0 102.1 101.592 0.50757 8.0255 0.063245 -#> ds 2 parent 1 103.8 100.058 3.74159 7.9043 0.473361 -#> ds 2 parent 1 108.6 100.058 8.54159 7.9043 1.080626 -#> ds 2 parent 3 91.0 97.060 -6.05952 7.6674 -0.790297 -#> ds 2 parent 3 84.9 97.060 -12.15952 7.6674 -1.585874 -#> ds 2 parent 7 79.3 91.329 -12.02867 7.2147 -1.667251 -#> ds 2 parent 7 100.9 91.329 9.57133 7.2147 1.326647 -#> ds 2 parent 14 77.3 82.102 -4.80185 6.4858 -0.740366 -#> ds 2 parent 14 83.5 82.102 1.39815 6.4858 0.215571 -#> ds 2 parent 28 66.8 66.351 0.44945 5.2415 0.085748 -#> ds 2 parent 28 63.3 66.351 -3.05055 5.2415 -0.582002 -#> ds 2 parent 60 40.8 40.775 0.02474 3.2211 0.007679 -#> ds 2 parent 60 44.8 40.775 4.02474 3.2211 1.249485 -#> ds 2 parent 90 27.8 25.832 1.96762 2.0407 0.964198 -#> ds 2 parent 90 27.0 25.832 1.16762 2.0407 0.572171 -#> ds 2 parent 120 15.2 16.366 -1.16561 1.2928 -0.901595 -#> ds 2 parent 120 15.5 16.366 -0.86561 1.2928 -0.669547 -#> ds 3 parent 0 97.7 101.592 -3.89243 8.0255 -0.485009 -#> ds 3 parent 0 88.2 101.592 -13.39243 8.0255 -1.668739 -#> ds 3 parent 1 109.9 99.218 10.68196 7.8379 1.362858 -#> ds 3 parent 1 97.8 99.218 -1.41804 7.8379 -0.180921 -#> ds 3 parent 3 100.5 94.634 5.86555 7.4758 0.784603 -#> ds 3 parent 3 77.4 94.634 -17.23445 7.4758 -2.305360 -#> ds 3 parent 7 78.3 86.093 -7.79273 6.8011 -1.145813 -#> ds 3 parent 7 90.3 86.093 4.20727 6.8011 0.618620 -#> ds 3 parent 14 76.0 72.958 3.04222 5.7634 0.527848 -#> ds 3 parent 14 79.1 72.958 6.14222 5.7634 1.065722 -#> ds 3 parent 28 46.0 52.394 -6.39404 4.1390 -1.544842 -#> ds 3 parent 28 53.4 52.394 1.00596 4.1390 0.243046 -#> ds 3 parent 60 25.1 24.582 0.51786 1.9419 0.266676 -#> ds 3 parent 60 21.4 24.582 -3.18214 1.9419 -1.638664 -#> ds 3 parent 90 11.0 12.092 -1.09202 0.9552 -1.143199 -#> ds 3 parent 90 14.2 12.092 2.10798 0.9552 2.206776 -#> ds 3 parent 120 5.8 5.948 -0.14810 0.4699 -0.315178 -#> ds 3 parent 120 6.1 5.948 0.15190 0.4699 0.323282 -#> ds 4 parent 0 95.3 101.592 -6.29243 8.0255 -0.784057 -#> ds 4 parent 0 102.0 101.592 0.40757 8.0255 0.050784 -#> ds 4 parent 1 104.4 101.125 3.27549 7.9885 0.410025 -#> ds 4 parent 1 105.4 101.125 4.27549 7.9885 0.535205 -#> ds 4 parent 3 113.7 100.195 13.50487 7.9151 1.706218 -#> ds 4 parent 3 82.3 100.195 -17.89513 7.9151 -2.260886 -#> ds 4 parent 7 98.1 98.362 -0.26190 7.7703 -0.033706 -#> ds 4 parent 7 87.8 98.362 -10.56190 7.7703 -1.359270 -#> ds 4 parent 14 97.9 95.234 2.66590 7.5232 0.354357 -#> ds 4 parent 14 104.8 95.234 9.56590 7.5232 1.271521 -#> ds 4 parent 28 85.0 89.274 -4.27372 7.0523 -0.606001 -#> ds 4 parent 28 77.2 89.274 -12.07372 7.0523 -1.712017 -#> ds 4 parent 60 82.2 77.013 5.18661 6.0838 0.852526 -#> ds 4 parent 60 86.1 77.013 9.08661 6.0838 1.493571 -#> ds 4 parent 90 70.5 67.053 3.44692 5.2970 0.650733 -#> ds 4 parent 90 61.7 67.053 -5.35308 5.2970 -1.010591 -#> ds 4 parent 120 60.0 58.381 1.61905 4.6119 0.351058 -#> ds 4 parent 120 56.4 58.381 -1.98095 4.6119 -0.429530 -#> ds 5 parent 0 92.6 101.592 -8.99243 8.0255 -1.120485 -#> ds 5 parent 0 116.5 101.592 14.90757 8.0255 1.857531 -#> ds 5 parent 1 108.0 99.914 8.08560 7.8929 1.024413 -#> ds 5 parent 1 104.9 99.914 4.98560 7.8929 0.631655 -#> ds 5 parent 3 100.5 96.641 3.85898 7.6343 0.505477 -#> ds 5 parent 3 89.5 96.641 -7.14102 7.6343 -0.935382 -#> ds 5 parent 7 91.7 90.412 1.28752 7.1423 0.180267 -#> ds 5 parent 7 95.1 90.412 4.68752 7.1423 0.656304 -#> ds 5 parent 14 82.2 80.463 1.73715 6.3563 0.273295 -#> ds 5 parent 14 84.5 80.463 4.03715 6.3563 0.635141 -#> ds 5 parent 28 60.5 63.728 -3.22788 5.0343 -0.641178 -#> ds 5 parent 28 72.8 63.728 9.07212 5.0343 1.802062 -#> ds 5 parent 60 38.3 37.399 0.90061 2.9544 0.304835 -#> ds 5 parent 60 40.7 37.399 3.30061 2.9544 1.117174 -#> ds 5 parent 90 22.5 22.692 -0.19165 1.7926 -0.106913 -#> ds 5 parent 90 20.8 22.692 -1.89165 1.7926 -1.055273 -#> ds 5 parent 120 13.4 13.768 -0.36790 1.0876 -0.338259 -#> ds 5 parent 120 13.8 13.768 0.03210 1.0876 0.029517</div><div class='input'> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="co"># Generate five datasets following SFO kinetics</span></span> +<span class="r-in"><span class="va">sampling_times</span> <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">1</span>, <span class="fl">3</span>, <span class="fl">7</span>, <span class="fl">14</span>, <span class="fl">28</span>, <span class="fl">60</span>, <span class="fl">90</span>, <span class="fl">120</span><span class="op">)</span></span> +<span class="r-in"><span class="va">dt50_sfo_in_pop</span> <span class="op"><-</span> <span class="fl">50</span></span> +<span class="r-in"><span class="va">k_in_pop</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/Log.html" class="external-link">log</a></span><span class="op">(</span><span class="fl">2</span><span class="op">)</span> <span class="op">/</span> <span class="va">dt50_sfo_in_pop</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/Random.html" class="external-link">set.seed</a></span><span class="op">(</span><span class="fl">1234</span><span class="op">)</span></span> +<span class="r-in"><span class="va">k_in</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/Lognormal.html" class="external-link">rlnorm</a></span><span class="op">(</span><span class="fl">5</span>, <span class="fu"><a href="https://rdrr.io/r/base/Log.html" class="external-link">log</a></span><span class="op">(</span><span class="va">k_in_pop</span><span class="op">)</span>, <span class="fl">0.5</span><span class="op">)</span></span> +<span class="r-in"><span class="va">SFO</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">pred_sfo</span> <span class="op"><-</span> <span class="kw">function</span><span class="op">(</span><span class="va">k</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="fu"><a href="mkinpredict.html">mkinpredict</a></span><span class="op">(</span><span class="va">SFO</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_parent <span class="op">=</span> <span class="va">k</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">sampling_times</span><span class="op">)</span></span> +<span class="r-in"><span class="op">}</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">ds_sfo_mean</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="va">k_in</span>, <span class="va">pred_sfo</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">ds_sfo_mean</span><span class="op">)</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste</a></span><span class="op">(</span><span class="st">"ds"</span>, <span class="fl">1</span><span class="op">:</span><span class="fl">5</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/Random.html" class="external-link">set.seed</a></span><span class="op">(</span><span class="fl">12345</span><span class="op">)</span></span> +<span class="r-in"><span class="va">ds_sfo_syn</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="va">ds_sfo_mean</span>, <span class="kw">function</span><span class="op">(</span><span class="va">ds</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="fu"><a href="add_err.html">add_err</a></span><span class="op">(</span><span class="va">ds</span>,</span> +<span class="r-in"> sdfunc <span class="op">=</span> <span class="kw">function</span><span class="op">(</span><span class="va">value</span><span class="op">)</span> <span class="fu"><a href="https://rdrr.io/r/base/MathFun.html" class="external-link">sqrt</a></span><span class="op">(</span><span class="fl">1</span><span class="op">^</span><span class="fl">2</span> <span class="op">+</span> <span class="va">value</span><span class="op">^</span><span class="fl">2</span> <span class="op">*</span> <span class="fl">0.07</span><span class="op">^</span><span class="fl">2</span><span class="op">)</span>,</span> +<span class="r-in"> n <span class="op">=</span> <span class="fl">1</span><span class="op">)</span><span class="op">[[</span><span class="fl">1</span><span class="op">]</span><span class="op">]</span></span> +<span class="r-in"><span class="op">}</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Evaluate using mmkin and nlme</span></span> +<span class="r-in"><span class="kw"><a href="https://rdrr.io/r/base/library.html" class="external-link">library</a></span><span class="op">(</span><span class="va"><a href="https://svn.r-project.org/R-packages/trunk/nlme/" class="external-link">nlme</a></span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_mmkin</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="va">ds_sfo_syn</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"tc"</span>, cores <span class="op">=</span> <span class="fl">1</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_nlme</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></span><span class="op">(</span><span class="va">f_mmkin</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/saemix/man/summary-methods.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">f_nlme</span>, data <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> nlme version used for fitting: 3.1.155 </span> +<span class="r-out co"><span class="r-pr">#></span> mkin version used for pre-fitting: 1.1.0 </span> +<span class="r-out co"><span class="r-pr">#></span> R version used for fitting: 4.1.2 </span> +<span class="r-out co"><span class="r-pr">#></span> Date of fit: Wed Mar 2 13:42:16 2022 </span> +<span class="r-out co"><span class="r-pr">#></span> Date of summary: Wed Mar 2 13:42:16 2022 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Equations:</span> +<span class="r-out co"><span class="r-pr">#></span> d_parent/dt = - k_parent * parent</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Data:</span> +<span class="r-out co"><span class="r-pr">#></span> 90 observations of 1 variable(s) grouped in 5 datasets</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model predictions using solution type analytical </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fitted in 0.545 s using 4 iterations</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Variance model: Two-component variance function </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Mean of starting values for individual parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_k_parent </span> +<span class="r-out co"><span class="r-pr">#></span> 101.569 -4.454 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fixed degradation parameter values:</span> +<span class="r-out co"><span class="r-pr">#></span> None</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Results:</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> AIC BIC logLik</span> +<span class="r-out co"><span class="r-pr">#></span> 584.5 599.5 -286.2</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Optimised, transformed parameters with symmetric confidence intervals:</span> +<span class="r-out co"><span class="r-pr">#></span> lower est. upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 99.371 101.592 103.814</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent -4.973 -4.449 -3.926</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Correlation: </span> +<span class="r-out co"><span class="r-pr">#></span> parnt_0</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent 0.0507 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Random effects:</span> +<span class="r-out co"><span class="r-pr">#></span> Formula: list(parent_0 ~ 1, log_k_parent ~ 1)</span> +<span class="r-out co"><span class="r-pr">#></span> Level: ds</span> +<span class="r-out co"><span class="r-pr">#></span> Structure: Diagonal</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_k_parent Residual</span> +<span class="r-out co"><span class="r-pr">#></span> StdDev: 6.924e-05 0.5863 1</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Variance function:</span> +<span class="r-out co"><span class="r-pr">#></span> Structure: Constant plus proportion of variance covariate</span> +<span class="r-out co"><span class="r-pr">#></span> Formula: ~fitted(.) </span> +<span class="r-out co"><span class="r-pr">#></span> Parameter estimates:</span> +<span class="r-out co"><span class="r-pr">#></span> const prop </span> +<span class="r-out co"><span class="r-pr">#></span> 0.0001208853 0.0789968036 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Backtransformed parameters with asymmetric confidence intervals:</span> +<span class="r-out co"><span class="r-pr">#></span> lower est. upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 99.370882 101.59243 103.81398</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.006923 0.01168 0.01972</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Estimated disappearance times:</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90</span> +<span class="r-out co"><span class="r-pr">#></span> parent 59.32 197.1</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Data:</span> +<span class="r-out co"><span class="r-pr">#></span> ds name time observed predicted residual std standardized</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 0 104.1 101.592 2.50757 8.0255 0.312451</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 0 105.0 101.592 3.40757 8.0255 0.424594</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 1 98.5 100.796 -2.29571 7.9625 -0.288313</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 1 96.1 100.796 -4.69571 7.9625 -0.589725</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 3 101.9 99.221 2.67904 7.8381 0.341796</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 3 85.2 99.221 -14.02096 7.8381 -1.788812</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 7 99.1 96.145 2.95512 7.5951 0.389081</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 7 93.0 96.145 -3.14488 7.5951 -0.414065</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 14 88.1 90.989 -2.88944 7.1879 -0.401987</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 14 84.1 90.989 -6.88944 7.1879 -0.958480</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 28 80.2 81.493 -1.29305 6.4377 -0.200857</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 28 91.3 81.493 9.80695 6.4377 1.523364</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 60 65.1 63.344 1.75642 5.0039 0.351008</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 60 65.8 63.344 2.45642 5.0039 0.490898</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 90 47.8 50.018 -2.21764 3.9512 -0.561252</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 90 53.5 50.018 3.48236 3.9512 0.881335</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 120 37.6 39.495 -1.89515 3.1200 -0.607423</span> +<span class="r-out co"><span class="r-pr">#></span> ds 1 parent 120 39.3 39.495 -0.19515 3.1200 -0.062549</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 0 107.9 101.592 6.30757 8.0255 0.785943</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 0 102.1 101.592 0.50757 8.0255 0.063245</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 1 103.8 100.058 3.74159 7.9043 0.473361</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 1 108.6 100.058 8.54159 7.9043 1.080626</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 3 91.0 97.060 -6.05952 7.6674 -0.790297</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 3 84.9 97.060 -12.15952 7.6674 -1.585874</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 7 79.3 91.329 -12.02867 7.2147 -1.667251</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 7 100.9 91.329 9.57133 7.2147 1.326647</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 14 77.3 82.102 -4.80185 6.4858 -0.740366</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 14 83.5 82.102 1.39815 6.4858 0.215571</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 28 66.8 66.351 0.44945 5.2415 0.085748</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 28 63.3 66.351 -3.05055 5.2415 -0.582002</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 60 40.8 40.775 0.02474 3.2211 0.007679</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 60 44.8 40.775 4.02474 3.2211 1.249485</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 90 27.8 25.832 1.96762 2.0407 0.964198</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 90 27.0 25.832 1.16762 2.0407 0.572171</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 120 15.2 16.366 -1.16561 1.2928 -0.901595</span> +<span class="r-out co"><span class="r-pr">#></span> ds 2 parent 120 15.5 16.366 -0.86561 1.2928 -0.669547</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 0 97.7 101.592 -3.89243 8.0255 -0.485009</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 0 88.2 101.592 -13.39243 8.0255 -1.668739</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 1 109.9 99.218 10.68196 7.8379 1.362858</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 1 97.8 99.218 -1.41804 7.8379 -0.180921</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 3 100.5 94.634 5.86555 7.4758 0.784603</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 3 77.4 94.634 -17.23445 7.4758 -2.305360</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 7 78.3 86.093 -7.79273 6.8011 -1.145813</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 7 90.3 86.093 4.20727 6.8011 0.618620</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 14 76.0 72.958 3.04222 5.7634 0.527848</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 14 79.1 72.958 6.14222 5.7634 1.065722</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 28 46.0 52.394 -6.39404 4.1390 -1.544842</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 28 53.4 52.394 1.00596 4.1390 0.243046</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 60 25.1 24.582 0.51786 1.9419 0.266676</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 60 21.4 24.582 -3.18214 1.9419 -1.638664</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 90 11.0 12.092 -1.09202 0.9552 -1.143199</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 90 14.2 12.092 2.10798 0.9552 2.206776</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 120 5.8 5.948 -0.14810 0.4699 -0.315178</span> +<span class="r-out co"><span class="r-pr">#></span> ds 3 parent 120 6.1 5.948 0.15190 0.4699 0.323282</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 0 95.3 101.592 -6.29243 8.0255 -0.784057</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 0 102.0 101.592 0.40757 8.0255 0.050784</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 1 104.4 101.125 3.27549 7.9885 0.410025</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 1 105.4 101.125 4.27549 7.9885 0.535205</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 3 113.7 100.195 13.50487 7.9151 1.706218</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 3 82.3 100.195 -17.89513 7.9151 -2.260886</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 7 98.1 98.362 -0.26190 7.7703 -0.033706</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 7 87.8 98.362 -10.56190 7.7703 -1.359270</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 14 97.9 95.234 2.66590 7.5232 0.354357</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 14 104.8 95.234 9.56590 7.5232 1.271521</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 28 85.0 89.274 -4.27372 7.0523 -0.606001</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 28 77.2 89.274 -12.07372 7.0523 -1.712017</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 60 82.2 77.013 5.18661 6.0838 0.852526</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 60 86.1 77.013 9.08661 6.0838 1.493571</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 90 70.5 67.053 3.44692 5.2970 0.650733</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 90 61.7 67.053 -5.35308 5.2970 -1.010591</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 120 60.0 58.381 1.61905 4.6119 0.351058</span> +<span class="r-out co"><span class="r-pr">#></span> ds 4 parent 120 56.4 58.381 -1.98095 4.6119 -0.429530</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 0 92.6 101.592 -8.99243 8.0255 -1.120485</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 0 116.5 101.592 14.90757 8.0255 1.857531</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 1 108.0 99.914 8.08560 7.8929 1.024413</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 1 104.9 99.914 4.98560 7.8929 0.631655</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 3 100.5 96.641 3.85898 7.6343 0.505477</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 3 89.5 96.641 -7.14102 7.6343 -0.935382</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 7 91.7 90.412 1.28752 7.1423 0.180267</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 7 95.1 90.412 4.68752 7.1423 0.656304</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 14 82.2 80.463 1.73715 6.3563 0.273295</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 14 84.5 80.463 4.03715 6.3563 0.635141</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 28 60.5 63.728 -3.22788 5.0343 -0.641178</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 28 72.8 63.728 9.07212 5.0343 1.802062</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 60 38.3 37.399 0.90061 2.9544 0.304835</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 60 40.7 37.399 3.30061 2.9544 1.117174</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 90 22.5 22.692 -0.19165 1.7926 -0.106913</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 90 20.8 22.692 -1.89165 1.7926 -1.055273</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 120 13.4 13.768 -0.36790 1.0876 -0.338259</span> +<span class="r-out co"><span class="r-pr">#></span> ds 5 parent 120 13.8 13.768 0.03210 1.0876 0.029517</span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/summary.nlmixr.mmkin.html b/docs/reference/summary.nlmixr.mmkin.html new file mode 100644 index 00000000..57541950 --- /dev/null +++ b/docs/reference/summary.nlmixr.mmkin.html @@ -0,0 +1,2917 @@ +<!DOCTYPE html> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Summary method for class "nlmixr.mmkin" — summary.nlmixr.mmkin • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Summary method for class " nlmixr.mmkin summary.nlmixr.mmkin><meta property="og:description" content="Lists model equations, initial parameter values, optimised parameters +for fixed effects (population), random effects (deviations from the +population mean) and residual error model, as well as the resulting +endpoints such as formation fractions and DT50 values. Optionally +(default is FALSE), the data are listed in full."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> +<script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> +<script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + + + <div class="container template-reference-topic"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <div class="container"> + <div class="navbar-header"> + <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> + <span class="sr-only">Toggle navigation</span> + <span class="icon-bar"></span> + <span class="icon-bar"></span> + <span class="icon-bar"></span> + </button> + <span class="navbar-brand"> + <a class="navbar-link" href="../index.html">mkin</a> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> + </span> + </div> + + <div id="navbar" class="navbar-collapse collapse"> + <ul class="nav navbar-nav"><li> + <a href="../reference/index.html">Functions and data</a> +</li> +<li class="dropdown"> + <a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-expanded="false"> + Articles + + <span class="caret"></span> + </a> + <ul class="dropdown-menu" role="menu"><li> + <a href="../articles/mkin.html">Introduction to mkin</a> + </li> + <li> + <a href="../articles/FOCUS_D.html">Example evaluation of FOCUS Example Dataset D</a> + </li> + <li> + <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> + </li> + <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> + <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> + </li> + <li> + <a href="../articles/web_only/compiled_models.html">Performance benefit by using compiled model definitions in mkin</a> + </li> + <li> + <a href="../articles/twa.html">Calculation of time weighted average concentrations with mkin</a> + </li> + <li> + <a href="../articles/web_only/NAFTA_examples.html">Example evaluation of NAFTA SOP Attachment examples</a> + </li> + <li> + <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> + </li> + </ul></li> +<li> + <a href="../news/index.html">News</a> +</li> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> + <span class="fab fa-github fa-lg"></span> + + </a> +</li> + </ul></div><!--/.nav-collapse --> + </div><!--/.container --> +</div><!--/.navbar --> + + + + </header><div class="row"> + <div class="col-md-9 contents"> + <div class="page-header"> + <h1>Summary method for class "nlmixr.mmkin"</h1> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/summary.nlmixr.mmkin.R" class="external-link"><code>R/summary.nlmixr.mmkin.R</code></a></small> + <div class="hidden name"><code>summary.nlmixr.mmkin.Rd</code></div> + </div> + + <div class="ref-description"> + <p>Lists model equations, initial parameter values, optimised parameters +for fixed effects (population), random effects (deviations from the +population mean) and residual error model, as well as the resulting +endpoints such as formation fractions and DT50 values. Optionally +(default is FALSE), the data are listed in full.</p> + </div> + + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for nlmixr.mmkin</span> +<span class="fu"><a href="https://rdrr.io/pkg/saemix/man/summary-methods.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">object</span>, data <span class="op">=</span> <span class="cn">FALSE</span>, verbose <span class="op">=</span> <span class="cn">FALSE</span>, distimes <span class="op">=</span> <span class="cn">TRUE</span>, <span class="va">...</span><span class="op">)</span> + +<span class="co"># S3 method for summary.nlmixr.mmkin</span> +<span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">x</span>, digits <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/Extremes.html" class="external-link">max</a></span><span class="op">(</span><span class="fl">3</span>, <span class="fu"><a href="https://rdrr.io/r/base/options.html" class="external-link">getOption</a></span><span class="op">(</span><span class="st">"digits"</span><span class="op">)</span> <span class="op">-</span> <span class="fl">3</span><span class="op">)</span>, verbose <span class="op">=</span> <span class="va">x</span><span class="op">$</span><span class="va">verbose</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>an object of class <a href="nlmixr.mmkin.html">nlmixr.mmkin</a></p></dd> +<dt>data</dt> +<dd><p>logical, indicating whether the full data should be included in +the summary.</p></dd> +<dt>verbose</dt> +<dd><p>Should the summary be verbose?</p></dd> +<dt>distimes</dt> +<dd><p>logical, indicating whether DT50 and DT90 values should be +included.</p></dd> +<dt>...</dt> +<dd><p>optional arguments passed to methods like <code>print</code>.</p></dd> +<dt>x</dt> +<dd><p>an object of class summary.nlmixr.mmkin</p></dd> +<dt>digits</dt> +<dd><p>Number of digits to use for printing</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>The summary function returns a list obtained in the fit, with at +least the following additional components</p> +<dl><dt>nlmixrversion, mkinversion, Rversion</dt> +<dd><p>The nlmixr, mkin and R versions used</p></dd> +<dt>date.fit, date.summary</dt> +<dd><p>The dates where the fit and the summary were +produced</p></dd> +<dt>diffs</dt> +<dd><p>The differential equations used in the degradation model</p></dd> +<dt>use_of_ff</dt> +<dd><p>Was maximum or minimum use made of formation fractions</p></dd> +<dt>data</dt> +<dd><p>The data</p></dd> +<dt>confint_back</dt> +<dd><p>Backtransformed parameters, with confidence intervals if available</p></dd> +<dt>ff</dt> +<dd><p>The estimated formation fractions derived from the fitted +model.</p></dd> +<dt>distimes</dt> +<dd><p>The DT50 and DT90 values for each observed variable.</p></dd> +<dt>SFORB</dt> +<dd><p>If applicable, eigenvalues of SFORB components of the model.</p></dd> +</dl><p>The print method is called for its side effect, i.e. printing the summary.</p> + </div> + <div id="author"> + <h2>Author</h2> + <p>Johannes Ranke for the mkin specific parts +nlmixr authors for the parts inherited from nlmixr.</p> + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="co"># Generate five datasets following DFOP-SFO kinetics</span></span> +<span class="r-in"><span class="va">sampling_times</span> <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">1</span>, <span class="fl">3</span>, <span class="fl">7</span>, <span class="fl">14</span>, <span class="fl">28</span>, <span class="fl">60</span>, <span class="fl">90</span>, <span class="fl">120</span><span class="op">)</span></span> +<span class="r-in"><span class="va">dfop_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="st">"m1"</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/Random.html" class="external-link">set.seed</a></span><span class="op">(</span><span class="fl">1234</span><span class="op">)</span></span> +<span class="r-in"><span class="va">k1_in</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/Lognormal.html" class="external-link">rlnorm</a></span><span class="op">(</span><span class="fl">5</span>, <span class="fu"><a href="https://rdrr.io/r/base/Log.html" class="external-link">log</a></span><span class="op">(</span><span class="fl">0.1</span><span class="op">)</span>, <span class="fl">0.3</span><span class="op">)</span></span> +<span class="r-in"><span class="va">k2_in</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/Lognormal.html" class="external-link">rlnorm</a></span><span class="op">(</span><span class="fl">5</span>, <span class="fu"><a href="https://rdrr.io/r/base/Log.html" class="external-link">log</a></span><span class="op">(</span><span class="fl">0.02</span><span class="op">)</span>, <span class="fl">0.3</span><span class="op">)</span></span> +<span class="r-in"><span class="va">g_in</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/Logistic.html" class="external-link">plogis</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/stats/Normal.html" class="external-link">rnorm</a></span><span class="op">(</span><span class="fl">5</span>, <span class="fu"><a href="https://rdrr.io/r/stats/Logistic.html" class="external-link">qlogis</a></span><span class="op">(</span><span class="fl">0.5</span><span class="op">)</span>, <span class="fl">0.3</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_parent_to_m1_in</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/Logistic.html" class="external-link">plogis</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/stats/Normal.html" class="external-link">rnorm</a></span><span class="op">(</span><span class="fl">5</span>, <span class="fu"><a href="https://rdrr.io/r/stats/Logistic.html" class="external-link">qlogis</a></span><span class="op">(</span><span class="fl">0.3</span><span class="op">)</span>, <span class="fl">0.3</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="va">k_m1_in</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/Lognormal.html" class="external-link">rlnorm</a></span><span class="op">(</span><span class="fl">5</span>, <span class="fu"><a href="https://rdrr.io/r/base/Log.html" class="external-link">log</a></span><span class="op">(</span><span class="fl">0.02</span><span class="op">)</span>, <span class="fl">0.3</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">pred_dfop_sfo</span> <span class="op"><-</span> <span class="kw">function</span><span class="op">(</span><span class="va">k1</span>, <span class="va">k2</span>, <span class="va">g</span>, <span class="va">f_parent_to_m1</span>, <span class="va">k_m1</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="fu"><a href="mkinpredict.html">mkinpredict</a></span><span class="op">(</span><span class="va">dfop_sfo</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k1 <span class="op">=</span> <span class="va">k1</span>, k2 <span class="op">=</span> <span class="va">k2</span>, g <span class="op">=</span> <span class="va">g</span>, f_parent_to_m1 <span class="op">=</span> <span class="va">f_parent_to_m1</span>, k_m1 <span class="op">=</span> <span class="va">k_m1</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span>, m1 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">sampling_times</span><span class="op">)</span></span> +<span class="r-in"><span class="op">}</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">ds_mean_dfop_sfo</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="fl">1</span><span class="op">:</span><span class="fl">5</span>, <span class="kw">function</span><span class="op">(</span><span class="va">i</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="fu"><a href="mkinpredict.html">mkinpredict</a></span><span class="op">(</span><span class="va">dfop_sfo</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k1 <span class="op">=</span> <span class="va">k1_in</span><span class="op">[</span><span class="va">i</span><span class="op">]</span>, k2 <span class="op">=</span> <span class="va">k2_in</span><span class="op">[</span><span class="va">i</span><span class="op">]</span>, g <span class="op">=</span> <span class="va">g_in</span><span class="op">[</span><span class="va">i</span><span class="op">]</span>,</span> +<span class="r-in"> f_parent_to_m1 <span class="op">=</span> <span class="va">f_parent_to_m1_in</span><span class="op">[</span><span class="va">i</span><span class="op">]</span>, k_m1 <span class="op">=</span> <span class="va">k_m1_in</span><span class="op">[</span><span class="va">i</span><span class="op">]</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span>, m1 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">sampling_times</span><span class="op">)</span></span> +<span class="r-in"><span class="op">}</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">ds_mean_dfop_sfo</span><span class="op">)</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste</a></span><span class="op">(</span><span class="st">"ds"</span>, <span class="fl">1</span><span class="op">:</span><span class="fl">5</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">ds_syn_dfop_sfo</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="va">ds_mean_dfop_sfo</span>, <span class="kw">function</span><span class="op">(</span><span class="va">ds</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="fu"><a href="add_err.html">add_err</a></span><span class="op">(</span><span class="va">ds</span>,</span> +<span class="r-in"> sdfunc <span class="op">=</span> <span class="kw">function</span><span class="op">(</span><span class="va">value</span><span class="op">)</span> <span class="fu"><a href="https://rdrr.io/r/base/MathFun.html" class="external-link">sqrt</a></span><span class="op">(</span><span class="fl">1</span><span class="op">^</span><span class="fl">2</span> <span class="op">+</span> <span class="va">value</span><span class="op">^</span><span class="fl">2</span> <span class="op">*</span> <span class="fl">0.07</span><span class="op">^</span><span class="fl">2</span><span class="op">)</span>,</span> +<span class="r-in"> n <span class="op">=</span> <span class="fl">1</span><span class="op">)</span><span class="op">[[</span><span class="fl">1</span><span class="op">]</span><span class="op">]</span></span> +<span class="r-in"><span class="op">}</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="co"># Evaluate using mmkin and nlmixr</span></span> +<span class="r-in"><span class="va">f_mmkin_dfop_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="va">dfop_sfo</span><span class="op">)</span>, <span class="va">ds_syn_dfop_sfo</span>,</span> +<span class="r-in"> quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"tc"</span>, cores <span class="op">=</span> <span class="fl">5</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_saemix_dfop_sfo</span> <span class="op"><-</span> <span class="fu">mkin</span><span class="fu">::</span><span class="fu"><a href="saem.html">saem</a></span><span class="op">(</span><span class="va">f_mmkin_dfop_sfo</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_nlme_dfop_sfo</span> <span class="op"><-</span> <span class="fu">mkin</span><span class="fu">::</span><span class="fu"><a href="https://rdrr.io/pkg/nlme/man/nlme.html" class="external-link">nlme</a></span><span class="op">(</span><span class="va">f_mmkin_dfop_sfo</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_nlmixr_dfop_sfo_saem</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_dfop_sfo</span>, est <span class="op">=</span> <span class="st">"saem"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> With est = 'saem', a different error model is required for each observed variableChanging the error model to 'obs_tc' (Two-component error for each observed variable)</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → generate SAEM model</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-out co"><span class="r-pr">#></span> 1: 99.5921 -3.9040 -2.1350 -3.7103 -2.0097 0.3217 6.6502 0.1520 0.5415 0.1995 0.3705 0.5588 7.9084 0.0824 7.5666 0.1777</span> +<span class="r-out co"><span class="r-pr">#></span> 2: 99.9835 -3.8650 -2.3586 -4.0306 -1.6536 0.0696 6.3177 0.1590 0.5144 0.1895 0.3520 0.5308 4.7746 0.0649 4.5667 0.0865</span> +<span class="r-out co"><span class="r-pr">#></span> 3: 1.0014e+02 -4.0173e+00 -2.3869e+00 -4.0840e+00 -1.2338e+00 3.4899e-02 6.0018e+00 1.5109e-01 4.8870e-01 1.8005e-01 3.3438e-01 5.0428e-01 2.8890e+00 7.0377e-02 2.9045e+00 9.5437e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 4: 1.0024e+02 -4.1414e+00 -2.4972e+00 -4.1082e+00 -1.0291e+00 -1.0684e-02 5.7017e+00 1.4354e-01 4.6427e-01 1.7105e-01 3.1766e-01 4.7907e-01 2.1715e+00 8.9921e-02 1.8765e+00 1.0403e-01</span> +<span class="r-out co"><span class="r-pr">#></span> 5: 1.0068e+02 -4.1132e+00 -2.4776e+00 -4.0576e+00 -1.0391e+00 -8.8738e-02 5.8192e+00 1.3636e-01 4.4106e-01 1.6249e-01 3.0177e-01 4.5512e-01 1.6349e+00 8.3197e-02 1.4947e+00 1.0221e-01</span> +<span class="r-out co"><span class="r-pr">#></span> 6: 1.0044e+02 -4.0883e+00 -2.3931e+00 -4.1068e+00 -9.5058e-01 -1.2696e-01 5.5283e+00 1.2954e-01 4.1900e-01 1.5437e-01 2.8669e-01 4.5581e-01 1.4126e+00 8.1219e-02 1.2286e+00 1.0043e-01</span> +<span class="r-out co"><span class="r-pr">#></span> 7: 1.0103e+02 -4.0833e+00 -2.4194e+00 -4.0894e+00 -9.8547e-01 5.2360e-03 9.8755e+00 1.2306e-01 3.9805e-01 1.4665e-01 2.7235e-01 5.3394e-01 1.3620e+00 7.9842e-02 1.0649e+00 1.0298e-01</span> +<span class="r-out co"><span class="r-pr">#></span> 8: 1.0106e+02 -4.0535e+00 -2.3489e+00 -4.0682e+00 -9.4455e-01 -9.4310e-02 9.3818e+00 1.1691e-01 3.7815e-01 1.3932e-01 2.5873e-01 5.0724e-01 1.2163e+00 7.0820e-02 1.0147e+00 9.2362e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 9: 1.0150e+02 -4.0498e+00 -2.4037e+00 -4.0719e+00 -9.3384e-01 -1.2384e-01 8.9127e+00 1.1107e-01 3.5924e-01 1.3235e-01 2.4580e-01 5.3463e-01 1.0849e+00 7.7513e-02 9.8295e-01 8.5927e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 10: 1.0089e+02 -4.0313e+00 -2.3670e+00 -4.0573e+00 -9.0269e-01 -1.6427e-01 8.4670e+00 1.0551e-01 3.4128e-01 1.2573e-01 2.3351e-01 5.4980e-01 1.1274e+00 7.6000e-02 9.8582e-01 8.9740e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 11: 1.0089e+02 -4.0664e+00 -2.3547e+00 -4.0554e+00 -9.3659e-01 -1.6900e-01 8.0437e+00 1.0024e-01 3.2422e-01 1.1945e-01 2.2183e-01 5.2231e-01 1.1513e+00 7.5801e-02 9.7638e-01 8.5324e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 12: 1.0067e+02 -4.0427e+00 -2.3729e+00 -4.0413e+00 -9.2169e-01 -2.0927e-01 8.6156e+00 9.5225e-02 3.0801e-01 1.1348e-01 2.1074e-01 6.0288e-01 1.1918e+00 7.4830e-02 9.1899e-01 8.7983e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 13: 1.0042e+02 -4.0387e+00 -2.3650e+00 -4.0623e+00 -9.3973e-01 -2.2277e-01 8.1848e+00 9.0463e-02 2.9260e-01 1.0780e-01 2.0020e-01 5.7274e-01 1.1022e+00 7.3652e-02 9.1657e-01 8.7973e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 14: 1.0020e+02 -4.0227e+00 -2.3586e+00 -4.0333e+00 -9.4451e-01 -1.8020e-01 7.7756e+00 8.5940e-02 2.7797e-01 1.0241e-01 1.9019e-01 5.4410e-01 1.0728e+00 8.0169e-02 7.8974e-01 9.0162e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 15: 1.0045e+02 -4.0209e+00 -2.3544e+00 -4.0187e+00 -8.9758e-01 -2.4348e-01 7.3868e+00 8.1643e-02 2.6408e-01 9.7291e-02 1.8068e-01 6.4534e-01 1.0287e+00 7.9387e-02 7.3357e-01 9.0858e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 16: 1.0061e+02 -4.0195e+00 -2.3678e+00 -4.0419e+00 -8.9130e-01 -2.4248e-01 7.0175e+00 7.7561e-02 2.5087e-01 9.2427e-02 1.7165e-01 6.7145e-01 1.0440e+00 7.9292e-02 8.4681e-01 8.5285e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 17: 1.0034e+02 -4.0298e+00 -2.3685e+00 -4.0637e+00 -8.9550e-01 -1.0712e-01 6.6666e+00 7.3683e-02 2.3833e-01 8.7805e-02 1.6307e-01 6.3788e-01 1.0827e+00 7.1441e-02 8.5278e-01 8.8090e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 18: 99.8774 -4.0600 -2.3805 -4.0726 -0.9545 -0.1196 6.3333 0.0700 0.2264 0.0834 0.1549 0.6060 1.0056 0.0751 0.8017 0.0877</span> +<span class="r-out co"><span class="r-pr">#></span> 19: 1.0055e+02 -4.0731e+00 -2.2711e+00 -4.0824e+00 -9.5827e-01 -5.9764e-02 6.0166e+00 6.6499e-02 2.1509e-01 7.9244e-02 1.4717e-01 5.7835e-01 9.3185e-01 7.9396e-02 8.2332e-01 9.1277e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 20: 1.0060e+02 -4.1023e+00 -2.2841e+00 -4.0757e+00 -9.7931e-01 -1.0440e-01 5.7158e+00 6.3174e-02 2.0434e-01 7.5282e-02 1.3981e-01 6.4675e-01 1.0006e+00 7.7840e-02 8.7958e-01 9.1512e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 21: 1.0095e+02 -4.0955e+00 -2.3274e+00 -4.1038e+00 -9.5611e-01 -5.2481e-02 5.8063e+00 6.0015e-02 1.9412e-01 7.1518e-02 1.3282e-01 6.4943e-01 1.0926e+00 7.2665e-02 9.0450e-01 8.6278e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 22: 1.0083e+02 -4.0789e+00 -2.3108e+00 -4.1074e+00 -9.6548e-01 -4.9665e-02 5.5160e+00 5.7014e-02 1.8441e-01 6.7942e-02 1.2618e-01 6.7304e-01 9.3297e-01 8.1042e-02 8.9206e-01 9.2336e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 23: 1.0114e+02 -4.0924e+00 -2.4027e+00 -4.0947e+00 -9.7291e-01 -5.0773e-02 5.2567e+00 5.4164e-02 1.7519e-01 6.5747e-02 1.1987e-01 7.3402e-01 9.7858e-01 8.2133e-02 8.4928e-01 8.8254e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 24: 1.0151e+02 -4.0787e+00 -2.3696e+00 -4.0712e+00 -9.5647e-01 -5.4136e-02 4.9938e+00 5.1456e-02 1.6643e-01 6.2460e-02 1.1388e-01 7.1847e-01 9.7548e-01 7.7691e-02 9.0418e-01 8.9115e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 25: 1.0158e+02 -4.0830e+00 -2.3384e+00 -4.0705e+00 -9.5727e-01 -8.4974e-02 4.7442e+00 4.8883e-02 1.5811e-01 5.9337e-02 1.0818e-01 6.8255e-01 1.0340e+00 7.4497e-02 9.0691e-01 9.0886e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 26: 1.0156e+02 -4.0784e+00 -2.3030e+00 -4.1027e+00 -9.5638e-01 -4.9456e-03 4.5069e+00 4.6439e-02 1.5021e-01 5.6370e-02 1.1189e-01 6.4842e-01 1.0537e+00 7.7612e-02 9.6725e-01 8.7824e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 27: 1.0198e+02 -4.0828e+00 -2.3006e+00 -4.0803e+00 -9.9402e-01 -8.3280e-02 4.2816e+00 4.4117e-02 1.4270e-01 5.3552e-02 1.3300e-01 6.1600e-01 9.1051e-01 7.7677e-02 9.5949e-01 8.6552e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 28: 1.0183e+02 -4.0871e+00 -2.2822e+00 -4.0596e+00 -9.9920e-01 -1.1469e-01 4.0675e+00 4.1911e-02 1.3556e-01 5.0874e-02 1.4021e-01 5.8520e-01 1.0294e+00 7.0917e-02 8.6440e-01 9.0301e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 29: 1.0171e+02 -4.0838e+00 -2.2606e+00 -4.0885e+00 -9.8937e-01 -6.6488e-02 4.3393e+00 3.9815e-02 1.2878e-01 4.8330e-02 1.3320e-01 5.5594e-01 1.0042e+00 8.1585e-02 8.5434e-01 8.6032e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 30: 1.0177e+02 -4.0861e+00 -2.2615e+00 -4.0670e+00 -9.9119e-01 -1.1322e-01 6.3058e+00 3.7825e-02 1.2942e-01 4.5914e-02 1.4223e-01 5.2814e-01 9.6301e-01 7.3336e-02 9.2366e-01 8.9276e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 31: 1.0160e+02 -4.0900e+00 -2.2455e+00 -4.0514e+00 -9.8754e-01 -2.2617e-01 5.9905e+00 3.5933e-02 1.2295e-01 4.3618e-02 1.3512e-01 5.2898e-01 1.0441e+00 7.6262e-02 1.0227e+00 8.3759e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 32: 1.0193e+02 -4.0967e+00 -2.2599e+00 -4.0295e+00 -9.8917e-01 -1.6626e-01 5.6910e+00 3.4137e-02 1.2620e-01 4.1437e-02 1.4303e-01 5.0253e-01 9.8083e-01 7.4136e-02 1.0031e+00 8.5124e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 33: 1.0215e+02 -4.0713e+00 -2.2563e+00 -4.0313e+00 -9.7361e-01 -1.8246e-01 5.4065e+00 3.2430e-02 1.1989e-01 3.9365e-02 1.5371e-01 4.7741e-01 9.6935e-01 8.0491e-02 9.7610e-01 8.0590e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 34: 1.0251e+02 -4.0707e+00 -2.2635e+00 -4.0387e+00 -9.2149e-01 -1.3452e-01 6.3940e+00 3.0808e-02 1.1389e-01 3.7397e-02 1.6720e-01 4.5354e-01 9.2449e-01 7.4355e-02 1.0505e+00 8.3049e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 35: 1.0278e+02 -4.0579e+00 -2.2877e+00 -4.0289e+00 -9.6632e-01 -1.2910e-01 6.0743e+00 2.9268e-02 1.0820e-01 3.5527e-02 1.7242e-01 4.3086e-01 1.0129e+00 7.3224e-02 1.0035e+00 7.9411e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 36: 1.0283e+02 -4.0771e+00 -2.2977e+00 -4.0108e+00 -9.5228e-01 -2.1781e-01 5.7706e+00 2.7805e-02 1.0279e-01 3.3751e-02 1.7034e-01 4.0932e-01 9.0249e-01 7.9917e-02 9.4562e-01 8.2391e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 37: 1.0228e+02 -4.0442e+00 -2.3061e+00 -4.0150e+00 -9.5376e-01 -1.4873e-01 5.4821e+00 2.6414e-02 9.7651e-02 3.2063e-02 1.7772e-01 3.8885e-01 9.0446e-01 8.1418e-02 9.7276e-01 8.3331e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 38: 1.0220e+02 -4.0454e+00 -2.3204e+00 -4.0207e+00 -9.3198e-01 -1.9324e-01 5.2080e+00 2.5094e-02 1.0946e-01 3.0460e-02 1.6883e-01 3.6941e-01 8.9159e-01 7.8645e-02 9.5848e-01 8.2734e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 39: 1.0193e+02 -4.0306e+00 -2.2926e+00 -4.0131e+00 -9.3448e-01 -2.1869e-01 6.7005e+00 2.3839e-02 1.0399e-01 2.8937e-02 1.6039e-01 3.5571e-01 9.0078e-01 7.8982e-02 9.3495e-01 8.3462e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 40: 1.0217e+02 -4.0463e+00 -2.2823e+00 -4.0209e+00 -9.2912e-01 -2.3580e-01 8.7857e+00 2.2647e-02 9.8789e-02 2.7490e-02 1.5418e-01 3.3792e-01 8.5126e-01 7.8849e-02 9.5510e-01 8.3011e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 41: 1.0210e+02 -4.0564e+00 -2.2213e+00 -4.0041e+00 -9.4137e-01 -2.4103e-01 9.2761e+00 2.1515e-02 9.5179e-02 2.6116e-02 1.4795e-01 3.9870e-01 9.8312e-01 7.1947e-02 1.0015e+00 8.1407e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 42: 1.0201e+02 -4.0204e+00 -2.2598e+00 -3.9984e+00 -9.4412e-01 -2.6838e-01 8.8123e+00 2.0439e-02 9.0420e-02 2.4810e-02 1.5013e-01 4.0334e-01 9.5583e-01 7.5617e-02 9.5131e-01 8.2343e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 43: 1.0244e+02 -4.0107e+00 -2.2178e+00 -3.9923e+00 -9.4481e-01 -3.1831e-01 8.3717e+00 1.9417e-02 9.5791e-02 2.3569e-02 1.5440e-01 4.8194e-01 9.4582e-01 7.4374e-02 9.7798e-01 8.3391e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 44: 1.0211e+02 -4.0193e+00 -2.2379e+00 -3.9784e+00 -9.2192e-01 -3.0224e-01 7.9531e+00 1.8446e-02 9.1002e-02 2.6623e-02 1.4668e-01 4.5785e-01 9.4162e-01 7.4503e-02 9.3229e-01 7.8428e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 45: 1.0183e+02 -4.0198e+00 -2.2150e+00 -3.9966e+00 -9.6219e-01 -3.0236e-01 7.5554e+00 1.7524e-02 8.6452e-02 2.8045e-02 1.4346e-01 4.3495e-01 9.3318e-01 7.5937e-02 9.4917e-01 8.2946e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 46: 1.0132e+02 -4.0245e+00 -2.2215e+00 -3.9954e+00 -9.4368e-01 -2.6878e-01 7.1777e+00 1.6648e-02 9.5839e-02 2.6909e-02 1.4633e-01 4.1321e-01 9.7698e-01 7.1947e-02 9.6599e-01 8.3812e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 47: 1.0138e+02 -4.0076e+00 -2.2741e+00 -4.0047e+00 -9.0608e-01 -2.2839e-01 6.8188e+00 1.5815e-02 9.2192e-02 2.5563e-02 1.6160e-01 3.9255e-01 9.3678e-01 7.4216e-02 1.0295e+00 7.9396e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 48: 1.0102e+02 -4.0235e+00 -2.2764e+00 -4.0123e+00 -9.1050e-01 -2.0555e-01 6.4778e+00 1.5024e-02 8.7583e-02 2.4285e-02 1.6368e-01 3.7292e-01 9.2204e-01 7.6976e-02 1.0289e+00 8.1381e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 49: 1.0074e+02 -4.0407e+00 -2.2583e+00 -4.0142e+00 -9.2682e-01 -2.5941e-01 6.1540e+00 1.4273e-02 8.3203e-02 2.3071e-02 1.8251e-01 3.5427e-01 9.0436e-01 7.4192e-02 1.0237e+00 8.2178e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 50: 1.0046e+02 -4.0626e+00 -2.2464e+00 -4.0201e+00 -9.3021e-01 -2.6983e-01 5.8463e+00 1.4303e-02 7.9043e-02 2.3395e-02 1.7339e-01 3.3846e-01 9.1334e-01 7.8046e-02 9.5881e-01 8.1223e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 51: 1.0022e+02 -4.0414e+00 -2.2373e+00 -4.0107e+00 -9.2183e-01 -2.6371e-01 5.8667e+00 1.8681e-02 7.5091e-02 2.2225e-02 1.6472e-01 3.7327e-01 9.4906e-01 8.0171e-02 1.0278e+00 8.7157e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 52: 1.0059e+02 -4.0444e+00 -2.2676e+00 -4.0263e+00 -9.1269e-01 -2.1748e-01 5.5734e+00 1.7747e-02 7.1337e-02 2.1114e-02 1.5648e-01 3.5461e-01 8.6417e-01 8.2918e-02 1.0332e+00 8.1690e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 53: 1.0071e+02 -4.0384e+00 -2.2530e+00 -4.0171e+00 -9.2997e-01 -2.5319e-01 5.2947e+00 1.6860e-02 6.7770e-02 2.0058e-02 1.6621e-01 3.3688e-01 8.9792e-01 7.8990e-02 1.0230e+00 7.9862e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 54: 1.0067e+02 -4.0271e+00 -2.2540e+00 -4.0251e+00 -9.2151e-01 -2.2197e-01 5.0300e+00 1.6017e-02 6.4381e-02 1.9055e-02 1.7025e-01 3.2003e-01 8.7999e-01 8.0187e-02 1.0487e+00 8.1091e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 55: 1.0083e+02 -4.0326e+00 -2.2090e+00 -4.0230e+00 -9.2078e-01 -2.4936e-01 4.8429e+00 1.5216e-02 6.1162e-02 1.8103e-02 1.7211e-01 3.0403e-01 8.8923e-01 8.2248e-02 1.0522e+00 8.0777e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 56: 1.0082e+02 -4.0284e+00 -2.2350e+00 -4.0083e+00 -8.9532e-01 -1.9565e-01 5.3306e+00 1.4455e-02 5.8104e-02 1.7197e-02 1.6350e-01 2.8883e-01 8.7438e-01 7.9530e-02 1.0748e+00 7.9892e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 57: 1.0089e+02 -4.0118e+00 -2.2585e+00 -3.9924e+00 -9.5279e-01 -2.7691e-01 5.4228e+00 1.3733e-02 5.5199e-02 1.6338e-02 1.9088e-01 2.7439e-01 9.3164e-01 8.0286e-02 1.1149e+00 8.3224e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 58: 1.0103e+02 -4.0117e+00 -2.2470e+00 -3.9628e+00 -9.5632e-01 -3.1385e-01 5.1517e+00 1.3046e-02 6.2482e-02 1.5521e-02 1.8744e-01 2.8144e-01 9.6857e-01 8.0586e-02 1.0149e+00 8.0615e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 59: 1.0110e+02 -4.0400e+00 -2.2319e+00 -3.9749e+00 -9.3280e-01 -3.1491e-01 4.8941e+00 1.4375e-02 7.6521e-02 1.9982e-02 1.8994e-01 2.6736e-01 9.9294e-01 7.6723e-02 9.8321e-01 8.4135e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 60: 1.0135e+02 -4.0401e+00 -2.2969e+00 -4.0006e+00 -9.3649e-01 -2.7105e-01 4.6494e+00 1.5352e-02 7.2695e-02 1.8983e-02 1.8339e-01 2.5400e-01 9.7671e-01 8.0731e-02 1.0344e+00 8.4798e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 61: 1.0139e+02 -4.0447e+00 -2.3267e+00 -4.0036e+00 -9.2609e-01 -2.4279e-01 4.4169e+00 1.4584e-02 6.9060e-02 1.8034e-02 1.7844e-01 2.4130e-01 9.4921e-01 8.1065e-02 1.0031e+00 8.2364e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 62: 1.0187e+02 -4.0605e+00 -2.2435e+00 -4.0093e+00 -9.4594e-01 -2.2911e-01 4.1961e+00 1.3855e-02 6.5607e-02 2.0229e-02 1.6951e-01 2.2923e-01 8.5507e-01 8.5043e-02 1.0003e+00 8.4881e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 63: 1.0181e+02 -4.0665e+00 -2.2106e+00 -3.9954e+00 -9.5259e-01 -2.2539e-01 3.9863e+00 1.3162e-02 6.2327e-02 1.9217e-02 2.0722e-01 2.1777e-01 9.2699e-01 7.9303e-02 9.8900e-01 8.5477e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 64: 1.0178e+02 -4.0641e+00 -2.2152e+00 -3.9904e+00 -9.7044e-01 -2.2671e-01 3.8289e+00 1.2504e-02 5.9210e-02 1.8256e-02 2.1010e-01 2.0688e-01 8.6741e-01 8.9748e-02 9.9564e-01 8.6675e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 65: 1.0149e+02 -4.0871e+00 -2.2063e+00 -4.0000e+00 -9.7253e-01 -2.0360e-01 3.6375e+00 1.1879e-02 5.8060e-02 1.7344e-02 2.3758e-01 1.9654e-01 9.1092e-01 8.6259e-02 1.0674e+00 8.6171e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 66: 1.0131e+02 -4.0863e+00 -2.2283e+00 -4.0026e+00 -9.6884e-01 -2.2153e-01 3.4556e+00 1.1285e-02 5.5157e-02 1.6476e-02 2.5128e-01 1.8671e-01 9.2512e-01 7.7687e-02 1.0847e+00 8.2689e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 67: 1.0124e+02 -4.0691e+00 -2.2261e+00 -4.0021e+00 -9.2647e-01 -2.9309e-01 3.2828e+00 1.0721e-02 5.2400e-02 1.5653e-02 2.3872e-01 1.7738e-01 8.3514e-01 8.7680e-02 1.0093e+00 8.1515e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 68: 1.0160e+02 -4.0653e+00 -2.2627e+00 -3.9685e+00 -9.5325e-01 -2.9870e-01 3.1187e+00 1.0185e-02 5.0455e-02 1.6013e-02 2.2678e-01 1.6851e-01 9.3016e-01 8.4873e-02 1.0357e+00 8.0066e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 69: 1.0154e+02 -4.0667e+00 -2.2536e+00 -3.9686e+00 -9.8329e-01 -2.1749e-01 2.9628e+00 9.6753e-03 4.7932e-02 1.6408e-02 2.1544e-01 1.6008e-01 9.4932e-01 8.5396e-02 1.0298e+00 8.2915e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 70: 1.0140e+02 -4.0718e+00 -2.2809e+00 -4.0031e+00 -9.7818e-01 -1.5912e-01 2.8146e+00 1.2376e-02 4.5536e-02 1.5606e-02 2.0467e-01 1.5208e-01 9.8171e-01 8.4966e-02 1.0881e+00 8.4583e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 71: 1.0119e+02 -4.0810e+00 -2.2832e+00 -3.9945e+00 -9.7859e-01 -1.6288e-01 2.6739e+00 1.1757e-02 4.3259e-02 2.2477e-02 1.9444e-01 1.4447e-01 9.2355e-01 8.4027e-02 1.0557e+00 8.3942e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 72: 1.0133e+02 -4.0904e+00 -2.2582e+00 -4.0034e+00 -1.0103e+00 -1.9818e-01 2.5402e+00 1.1169e-02 6.0710e-02 2.4943e-02 1.8472e-01 1.3725e-01 8.8530e-01 8.8313e-02 9.6043e-01 8.6565e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 73: 1.0081e+02 -4.0852e+00 -2.2408e+00 -4.0324e+00 -9.8147e-01 -2.0245e-01 2.4132e+00 1.0611e-02 6.0672e-02 2.3696e-02 1.7586e-01 1.5058e-01 9.8632e-01 8.0072e-02 1.0754e+00 8.4211e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 74: 1.0096e+02 -4.0784e+00 -2.2415e+00 -4.0085e+00 -9.6374e-01 -2.1820e-01 2.2925e+00 1.0080e-02 7.8175e-02 2.2511e-02 2.0451e-01 1.4305e-01 9.7218e-01 7.5856e-02 1.0703e+00 8.2684e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 75: 1.0059e+02 -4.0614e+00 -2.2571e+00 -4.0069e+00 -9.6858e-01 -2.2415e-01 2.1779e+00 9.5763e-03 7.4266e-02 2.1385e-02 2.0050e-01 1.3590e-01 9.4625e-01 8.3873e-02 1.0545e+00 8.0628e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 76: 1.0071e+02 -4.0570e+00 -2.2509e+00 -4.0111e+00 -9.4159e-01 -2.0936e-01 2.0690e+00 9.0975e-03 1.0546e-01 2.0316e-02 1.9048e-01 1.2911e-01 9.1139e-01 8.4290e-02 1.0164e+00 8.0587e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 77: 1.0056e+02 -4.0315e+00 -2.2434e+00 -4.0068e+00 -9.1913e-01 -2.0655e-01 1.9656e+00 8.6426e-03 1.2867e-01 1.9300e-02 1.8971e-01 1.5112e-01 9.1748e-01 8.0221e-02 1.0080e+00 8.2126e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 78: 1.0054e+02 -4.0350e+00 -2.2335e+00 -4.0109e+00 -9.4315e-01 -1.7472e-01 2.6310e+00 8.2105e-03 1.3206e-01 1.8867e-02 2.0835e-01 1.8443e-01 9.7893e-01 7.9595e-02 1.0622e+00 8.3669e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 79: 1.0036e+02 -4.0500e+00 -2.2739e+00 -4.0223e+00 -9.6070e-01 -1.8756e-01 2.5665e+00 7.7999e-03 1.2546e-01 1.7924e-02 1.9794e-01 2.0106e-01 9.4360e-01 8.0070e-02 1.0209e+00 8.4807e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 80: 1.0030e+02 -4.0522e+00 -2.2890e+00 -4.0149e+00 -9.2615e-01 -2.1233e-01 2.4382e+00 7.4099e-03 1.2570e-01 1.7028e-02 1.8804e-01 2.4730e-01 9.6559e-01 8.0105e-02 1.0382e+00 7.9028e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 81: 1.0004e+02 -4.0462e+00 -2.2766e+00 -4.0158e+00 -9.0841e-01 -2.3731e-01 3.0663e+00 7.0394e-03 1.2300e-01 1.6176e-02 1.7864e-01 2.3493e-01 8.8273e-01 8.0620e-02 1.0835e+00 7.9915e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 82: 1.0015e+02 -4.0106e+00 -2.2696e+00 -3.9845e+00 -9.2535e-01 -2.7387e-01 2.9130e+00 6.6875e-03 1.5058e-01 1.5368e-02 1.6971e-01 2.4826e-01 1.0039e+00 7.8035e-02 1.1181e+00 8.5136e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 83: 1.0019e+02 -4.0111e+00 -2.2266e+00 -3.9884e+00 -8.8579e-01 -2.3822e-01 2.7674e+00 6.3531e-03 1.9061e-01 1.4599e-02 1.6122e-01 2.3585e-01 1.0256e+00 8.1065e-02 1.0988e+00 8.4111e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 84: 99.9333 -4.0014 -2.2848 -3.9877 -0.8906 -0.2014 2.6290 0.0060 0.2388 0.0139 0.1532 0.2628 0.9936 0.0809 1.1059 0.0847</span> +<span class="r-out co"><span class="r-pr">#></span> 85: 99.6658 -4.0093 -2.2848 -3.9884 -0.8922 -0.2517 2.4976 0.0057 0.2269 0.0132 0.1455 0.2920 0.9705 0.0823 1.0458 0.0834</span> +<span class="r-out co"><span class="r-pr">#></span> 86: 99.8823 -4.0064 -2.2659 -4.0038 -0.9174 -0.1848 2.3727 0.0054 0.2155 0.0125 0.1382 0.2774 0.9699 0.0796 0.9808 0.0839</span> +<span class="r-out co"><span class="r-pr">#></span> 87: 1.0051e+02 -4.0156e+00 -2.2877e+00 -4.0160e+00 -8.9867e-01 -1.3463e-01 2.3477e+00 6.2688e-03 2.0474e-01 1.1891e-02 1.4859e-01 2.6352e-01 9.0742e-01 7.8361e-02 1.0082e+00 8.1020e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 88: 1.0036e+02 -4.0013e+00 -2.2738e+00 -4.0184e+00 -9.1589e-01 -1.4154e-01 3.0581e+00 7.7930e-03 2.5551e-01 1.1297e-02 1.4116e-01 2.5035e-01 9.8581e-01 7.6769e-02 9.7255e-01 8.8653e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 89: 1.0031e+02 -4.0155e+00 -2.3418e+00 -4.0080e+00 -8.8958e-01 -1.4006e-01 3.3754e+00 7.4891e-03 2.4274e-01 1.2919e-02 1.3411e-01 2.3783e-01 8.9921e-01 8.3685e-02 9.2657e-01 8.1804e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 90: 1.0044e+02 -4.0279e+00 -2.3328e+00 -4.0081e+00 -9.1868e-01 -1.3077e-01 3.6776e+00 1.1221e-02 2.3380e-01 1.2419e-02 1.4247e-01 2.2594e-01 8.8620e-01 8.0520e-02 9.0269e-01 8.2413e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 91: 1.0007e+02 -4.0329e+00 -2.3865e+00 -4.0145e+00 -8.9566e-01 -1.2400e-01 3.7450e+00 1.0660e-02 2.2211e-01 1.3667e-02 1.3534e-01 2.1539e-01 9.5638e-01 8.0235e-02 9.4346e-01 8.5828e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 92: 1.0025e+02 -4.0506e+00 -2.3252e+00 -4.0445e+00 -9.2023e-01 -5.6654e-02 3.9282e+00 1.0127e-02 2.4912e-01 1.2984e-02 1.4349e-01 2.6955e-01 9.6021e-01 7.7975e-02 9.1878e-01 8.6695e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 93: 1.0091e+02 -4.0566e+00 -2.2760e+00 -4.0422e+00 -9.2960e-01 -5.8179e-02 3.7318e+00 9.6210e-03 2.6385e-01 1.3422e-02 1.5136e-01 2.5607e-01 9.7012e-01 7.7323e-02 1.0157e+00 8.6123e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 94: 1.0045e+02 -4.0682e+00 -2.3163e+00 -4.0391e+00 -9.3398e-01 -1.0367e-01 4.0009e+00 9.1399e-03 2.5066e-01 1.2751e-02 1.6029e-01 2.9867e-01 9.1442e-01 8.0048e-02 9.7607e-01 8.5436e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 95: 1.0029e+02 -4.0790e+00 -2.2791e+00 -4.0470e+00 -9.4031e-01 -7.2610e-02 3.8008e+00 8.6829e-03 2.3813e-01 1.2114e-02 1.5227e-01 2.8373e-01 8.9105e-01 8.2168e-02 9.5542e-01 8.5308e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 96: 1.0017e+02 -4.0818e+00 -2.3204e+00 -4.0507e+00 -9.2181e-01 -7.5195e-02 3.6108e+00 8.2488e-03 2.2622e-01 1.1508e-02 1.5273e-01 2.6955e-01 9.3179e-01 7.7026e-02 1.0092e+00 8.4966e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 97: 1.0007e+02 -4.0721e+00 -2.3606e+00 -4.0453e+00 -9.4375e-01 -7.2811e-02 3.4303e+00 1.0904e-02 2.1585e-01 1.2641e-02 1.8282e-01 2.5788e-01 9.3750e-01 8.0427e-02 9.3193e-01 8.3262e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 98: 1.0024e+02 -4.1025e+00 -2.3916e+00 -4.0401e+00 -9.6711e-01 -6.7764e-02 3.2587e+00 1.0359e-02 2.0506e-01 1.8712e-02 1.9260e-01 2.4499e-01 1.0086e+00 7.7282e-02 9.6010e-01 8.1760e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 99: 1.0024e+02 -4.0755e+00 -2.3237e+00 -4.0581e+00 -9.5543e-01 -8.1716e-02 3.0958e+00 9.8408e-03 1.9481e-01 1.7973e-02 1.8297e-01 2.5653e-01 8.6589e-01 7.7940e-02 9.2919e-01 8.4396e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 100: 1.0039e+02 -4.0828e+00 -2.2976e+00 -4.0616e+00 -9.8223e-01 -8.5593e-02 3.9873e+00 9.3488e-03 1.8507e-01 1.8837e-02 1.7382e-01 2.4370e-01 8.6471e-01 8.4021e-02 9.4587e-01 8.1697e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 101: 1.0089e+02 -4.0738e+00 -2.3406e+00 -4.0465e+00 -9.4824e-01 -4.4055e-02 5.2624e+00 8.8814e-03 1.8051e-01 1.7896e-02 1.6513e-01 2.3288e-01 8.4179e-01 8.2487e-02 8.8097e-01 8.1625e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 102: 1.0090e+02 -4.0777e+00 -2.3244e+00 -4.0500e+00 -9.4069e-01 -5.2554e-02 5.5339e+00 8.4373e-03 1.7148e-01 1.7001e-02 1.5688e-01 2.2124e-01 9.0419e-01 7.8446e-02 9.4721e-01 8.0896e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 103: 1.0067e+02 -4.0658e+00 -2.3188e+00 -4.0312e+00 -9.5981e-01 -7.3735e-02 7.0281e+00 8.0154e-03 1.6291e-01 1.6151e-02 1.7019e-01 2.1018e-01 9.3631e-01 8.1516e-02 9.8773e-01 8.0587e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 104: 1.0015e+02 -4.0729e+00 -2.3830e+00 -4.0458e+00 -9.4446e-01 -5.0075e-02 6.6767e+00 7.6147e-03 1.5476e-01 1.5343e-02 1.6822e-01 1.9967e-01 8.2373e-01 8.3029e-02 9.6909e-01 7.9505e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 105: 1.0022e+02 -4.0888e+00 -2.3301e+00 -4.0411e+00 -9.5279e-01 -1.1412e-01 6.3429e+00 7.2339e-03 1.4702e-01 1.4576e-02 1.8886e-01 2.2088e-01 9.2925e-01 7.3020e-02 1.0450e+00 8.6511e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 106: 1.0013e+02 -4.0846e+00 -2.3428e+00 -4.0530e+00 -9.1649e-01 -8.1899e-02 6.0257e+00 6.8722e-03 1.3967e-01 1.8939e-02 1.8350e-01 2.1970e-01 9.4571e-01 8.6259e-02 8.8509e-01 8.1023e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 107: 1.0026e+02 -4.0954e+00 -2.3362e+00 -4.0586e+00 -9.6302e-01 -8.0898e-03 5.7244e+00 6.5286e-03 1.3269e-01 2.2595e-02 2.0043e-01 2.4151e-01 8.8882e-01 8.8155e-02 8.2466e-01 8.5467e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 108: 1.0109e+02 -4.0796e+00 -2.3980e+00 -4.0841e+00 -9.5525e-01 2.0583e-02 5.4382e+00 6.2022e-03 1.2606e-01 3.4423e-02 2.2509e-01 2.3732e-01 9.0211e-01 8.1331e-02 9.2728e-01 8.4409e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 109: 1.0091e+02 -4.0872e+00 -2.3614e+00 -4.0620e+00 -9.5950e-01 -1.8283e-02 5.1663e+00 6.1750e-03 1.1975e-01 3.2702e-02 2.1384e-01 2.2546e-01 9.7296e-01 7.7298e-02 9.7366e-01 8.3784e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 110: 1.0137e+02 -4.0637e+00 -2.3734e+00 -4.0781e+00 -9.3874e-01 -6.0140e-03 4.9080e+00 6.5148e-03 1.1376e-01 3.1066e-02 2.0314e-01 2.3943e-01 9.2451e-01 8.4473e-02 9.7311e-01 8.4958e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 111: 1.0181e+02 -4.0588e+00 -2.3200e+00 -4.0792e+00 -9.9395e-01 -3.1776e-02 4.6626e+00 9.9112e-03 1.0808e-01 4.1755e-02 1.9299e-01 2.9896e-01 1.0697e+00 7.1561e-02 1.0062e+00 8.8034e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 112: 1.0222e+02 -4.0566e+00 -2.3525e+00 -4.0607e+00 -9.6055e-01 -6.3691e-02 4.4850e+00 9.4157e-03 1.0267e-01 4.0540e-02 1.8334e-01 3.5699e-01 1.0213e+00 7.5944e-02 1.0070e+00 8.3434e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 113: 1.0189e+02 -4.0478e+00 -2.3774e+00 -4.0434e+00 -9.6638e-01 -6.7729e-02 5.1753e+00 8.9449e-03 9.7539e-02 3.8513e-02 2.0339e-01 3.4044e-01 9.5484e-01 7.7854e-02 9.8545e-01 8.1852e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 114: 1.0225e+02 -4.0334e+00 -2.3728e+00 -4.0502e+00 -9.4795e-01 -7.3569e-02 4.9165e+00 8.8152e-03 9.2662e-02 3.7310e-02 2.0002e-01 3.2342e-01 9.3586e-01 8.1063e-02 9.5652e-01 8.3067e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 115: 1.0196e+02 -4.0302e+00 -2.3599e+00 -4.0812e+00 -9.6783e-01 7.1536e-03 4.8473e+00 9.4780e-03 1.0791e-01 3.7184e-02 1.9002e-01 3.0725e-01 9.1488e-01 7.6079e-02 1.0104e+00 8.7136e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 116: 1.0150e+02 -4.0420e+00 -2.3637e+00 -4.0535e+00 -9.4545e-01 -7.6387e-02 4.6049e+00 9.6408e-03 1.0251e-01 3.8115e-02 1.8052e-01 2.9189e-01 9.0583e-01 8.2597e-02 9.5680e-01 8.1246e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 117: 1.0161e+02 -4.0606e+00 -2.3853e+00 -4.0750e+00 -9.7273e-01 -2.7338e-03 4.3747e+00 9.1587e-03 9.7386e-02 3.7863e-02 1.8701e-01 2.7729e-01 8.4511e-01 8.4164e-02 9.4149e-01 8.0525e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 118: 1.0174e+02 -4.0727e+00 -2.3776e+00 -4.0850e+00 -9.6982e-01 -1.2188e-03 4.1560e+00 8.7008e-03 9.2516e-02 4.9300e-02 2.1364e-01 2.6343e-01 9.5447e-01 8.6627e-02 9.1835e-01 8.1284e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 119: 1.0141e+02 -4.0887e+00 -2.3138e+00 -4.0772e+00 -9.9409e-01 -5.0120e-02 3.9482e+00 8.2658e-03 8.7891e-02 4.6835e-02 2.5364e-01 2.5026e-01 9.4576e-01 8.4355e-02 9.5762e-01 8.5430e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 120: 1.0116e+02 -4.1014e+00 -2.3328e+00 -4.0418e+00 -9.7139e-01 -8.9664e-02 3.7508e+00 7.8525e-03 8.3496e-02 4.4493e-02 2.4096e-01 2.3774e-01 9.2816e-01 8.5558e-02 9.7817e-01 8.5169e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 121: 1.0099e+02 -4.0876e+00 -2.3277e+00 -4.0746e+00 -9.5453e-01 -2.6752e-02 3.5632e+00 7.4598e-03 7.9321e-02 4.2269e-02 2.2891e-01 2.2586e-01 8.9613e-01 8.0488e-02 9.7590e-01 8.4798e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 122: 1.0171e+02 -4.0620e+00 -2.3349e+00 -4.0659e+00 -9.4420e-01 -1.6907e-02 3.3851e+00 7.0869e-03 8.8424e-02 4.0155e-02 2.1747e-01 2.1456e-01 9.0159e-01 7.8017e-02 9.8579e-01 8.4585e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 123: 1.0191e+02 -4.0708e+00 -2.3487e+00 -4.0827e+00 -9.5025e-01 -5.7459e-03 3.2158e+00 6.7325e-03 1.0499e-01 3.8147e-02 2.0659e-01 2.0384e-01 9.6378e-01 7.4758e-02 9.6268e-01 8.4712e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 124: 1.0224e+02 -4.0798e+00 -2.2989e+00 -4.0724e+00 -9.8452e-01 -3.1802e-02 3.0550e+00 6.3959e-03 9.9739e-02 3.6240e-02 1.9626e-01 1.9364e-01 9.4424e-01 7.4219e-02 9.9842e-01 8.4793e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 125: 1.0242e+02 -4.0710e+00 -2.3242e+00 -4.0661e+00 -1.0094e+00 -2.9970e-02 2.9023e+00 6.0761e-03 9.4752e-02 3.6130e-02 1.8645e-01 1.8396e-01 9.2576e-01 8.0533e-02 9.9407e-01 8.1660e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 126: 1.0254e+02 -4.0685e+00 -2.3356e+00 -4.0599e+00 -1.0031e+00 4.0250e-03 2.7571e+00 5.7723e-03 1.0658e-01 3.4324e-02 1.7971e-01 1.7476e-01 9.4870e-01 7.4027e-02 9.2757e-01 8.3091e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 127: 1.0270e+02 -4.0492e+00 -2.3174e+00 -4.0476e+00 -9.9898e-01 -6.3197e-02 2.6193e+00 5.4837e-03 1.0746e-01 3.2607e-02 1.7072e-01 1.6603e-01 9.0721e-01 7.7941e-02 9.4624e-01 8.1077e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 128: 1.0284e+02 -4.0582e+00 -2.2991e+00 -4.0331e+00 -9.9114e-01 -5.6800e-02 2.4883e+00 5.2095e-03 1.2321e-01 3.1304e-02 1.6219e-01 1.5772e-01 8.7403e-01 8.4147e-02 8.9187e-01 8.5089e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 129: 1.0275e+02 -4.0773e+00 -2.2935e+00 -4.0389e+00 -9.9661e-01 -7.4747e-02 2.3639e+00 4.9922e-03 1.1705e-01 2.9738e-02 1.9667e-01 1.4984e-01 9.1481e-01 8.4947e-02 9.3224e-01 8.5270e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 130: 1.0222e+02 -4.0835e+00 -2.3177e+00 -4.0343e+00 -1.0044e+00 -7.6530e-02 2.2457e+00 4.7426e-03 1.1120e-01 3.1348e-02 2.0663e-01 1.4235e-01 1.0173e+00 7.4769e-02 9.9905e-01 8.6058e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 131: 1.0202e+02 -4.0767e+00 -2.2497e+00 -4.0270e+00 -1.0015e+00 -1.4868e-01 2.1334e+00 5.5790e-03 1.0564e-01 2.9781e-02 2.1254e-01 1.3523e-01 1.0223e+00 7.7587e-02 9.4151e-01 8.4206e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 132: 1.0191e+02 -4.0756e+00 -2.2363e+00 -4.0081e+00 -9.7264e-01 -2.0991e-01 2.0268e+00 5.3000e-03 1.0184e-01 2.8291e-02 2.0191e-01 1.7667e-01 9.2404e-01 7.9813e-02 9.2266e-01 8.6307e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 133: 1.0187e+02 -4.0743e+00 -2.1951e+00 -4.0196e+00 -9.7534e-01 -1.8742e-01 1.9254e+00 5.0350e-03 9.6744e-02 2.6877e-02 1.9181e-01 1.6784e-01 1.0007e+00 8.2043e-02 1.0028e+00 8.3921e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 134: 1.0182e+02 -4.0731e+00 -2.2321e+00 -4.0041e+00 -9.2800e-01 -1.4985e-01 1.8291e+00 4.7833e-03 9.1906e-02 2.7751e-02 1.8222e-01 1.6415e-01 9.7093e-01 7.5558e-02 9.8455e-01 8.4921e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 135: 1.0188e+02 -4.0724e+00 -2.2774e+00 -4.0213e+00 -9.3930e-01 -1.7385e-01 1.7377e+00 4.5441e-03 8.7311e-02 2.6363e-02 1.7311e-01 1.5594e-01 9.4053e-01 8.3922e-02 9.8689e-01 8.1203e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 136: 1.0202e+02 -4.0712e+00 -2.2711e+00 -4.0128e+00 -9.8747e-01 -1.3610e-01 1.6508e+00 4.3169e-03 1.0383e-01 2.5045e-02 1.8004e-01 1.4814e-01 9.6497e-01 8.1397e-02 1.0782e+00 8.2539e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 137: 1.0228e+02 -4.0676e+00 -2.2403e+00 -4.0069e+00 -9.7761e-01 -1.5314e-01 1.5683e+00 4.1011e-03 1.0931e-01 2.4722e-02 1.8328e-01 1.4074e-01 9.8300e-01 7.5906e-02 1.0221e+00 8.2306e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 138: 1.0229e+02 -4.0654e+00 -2.2510e+00 -3.9908e+00 -1.0400e+00 -1.4173e-01 1.4899e+00 4.2166e-03 1.3448e-01 2.3486e-02 1.8272e-01 1.3370e-01 1.0305e+00 8.0580e-02 1.0988e+00 8.3512e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 139: 1.0258e+02 -4.0599e+00 -2.2207e+00 -3.9622e+00 -1.0058e+00 -2.6676e-01 1.4154e+00 4.0057e-03 1.5190e-01 2.2312e-02 1.7359e-01 1.2702e-01 9.6425e-01 8.6887e-02 1.0373e+00 8.3853e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 140: 1.0224e+02 -4.0665e+00 -2.2479e+00 -4.0063e+00 -1.0054e+00 -1.6109e-01 1.3446e+00 3.8054e-03 1.4430e-01 2.4389e-02 1.6697e-01 1.2066e-01 9.9245e-01 8.3900e-02 1.1218e+00 8.2527e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 141: 1.0245e+02 -4.0843e+00 -2.2024e+00 -3.9657e+00 -1.0057e+00 -2.4900e-01 1.2774e+00 3.6152e-03 1.3709e-01 2.3170e-02 1.8559e-01 1.1463e-01 9.4091e-01 8.7616e-02 1.0760e+00 8.1871e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 142: 1.0253e+02 -4.0972e+00 -2.1943e+00 -3.9649e+00 -1.0160e+00 -2.9535e-01 1.2135e+00 3.4344e-03 1.6892e-01 2.2011e-02 1.7631e-01 1.0890e-01 9.2146e-01 9.0207e-02 1.0645e+00 8.5078e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 143: 1.0252e+02 -4.1005e+00 -2.1652e+00 -3.9687e+00 -1.0445e+00 -2.4274e-01 2.0559e+00 3.9136e-03 1.6047e-01 2.0911e-02 1.6750e-01 1.0345e-01 9.0785e-01 8.5522e-02 1.1734e+00 8.5544e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 144: 1.0257e+02 -4.1199e+00 -2.1994e+00 -3.9618e+00 -1.0480e+00 -2.0099e-01 1.9531e+00 4.2739e-03 1.5745e-01 1.9865e-02 1.6053e-01 9.8282e-02 9.3710e-01 8.5496e-02 1.0597e+00 8.4335e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 145: 1.0282e+02 -4.1356e+00 -2.1489e+00 -3.9708e+00 -1.0268e+00 -2.2250e-01 1.8554e+00 4.0602e-03 1.7177e-01 1.8872e-02 1.5251e-01 9.3368e-02 9.5312e-01 8.3609e-02 1.0695e+00 8.3492e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 146: 1.0282e+02 -4.1443e+00 -2.2103e+00 -3.9821e+00 -1.0080e+00 -2.2414e-01 1.7627e+00 4.0693e-03 1.6460e-01 1.7928e-02 1.5576e-01 8.8699e-02 9.8656e-01 8.4549e-02 1.0251e+00 7.9572e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 147: 1.0295e+02 -4.1363e+00 -2.1920e+00 -3.9828e+00 -1.0567e+00 -1.9047e-01 1.6745e+00 3.8659e-03 1.6104e-01 1.7032e-02 1.6551e-01 8.4264e-02 9.4144e-01 8.7085e-02 1.0623e+00 8.1949e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 148: 1.0299e+02 -4.1336e+00 -2.1967e+00 -3.9921e+00 -1.0425e+00 -1.7466e-01 1.7992e+00 3.6726e-03 1.5298e-01 1.9937e-02 1.9453e-01 8.0051e-02 9.9498e-01 8.3001e-02 1.0884e+00 8.1599e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 149: 1.0292e+02 -4.1282e+00 -2.2741e+00 -4.0028e+00 -1.0650e+00 -1.4879e-01 2.1425e+00 3.4890e-03 1.4534e-01 1.8941e-02 2.0240e-01 7.6049e-02 1.0080e+00 7.9550e-02 1.1679e+00 7.9115e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 150: 1.0302e+02 -4.1402e+00 -2.2769e+00 -4.0056e+00 -1.0488e+00 -1.2845e-01 2.7814e+00 3.3145e-03 1.3807e-01 2.0220e-02 1.9228e-01 7.2246e-02 9.9253e-01 8.0215e-02 1.0075e+00 8.2295e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 151: 1.0304e+02 -4.1281e+00 -2.2250e+00 -4.0169e+00 -1.0448e+00 -1.4468e-01 2.6423e+00 3.1488e-03 1.3117e-01 2.1298e-02 1.8267e-01 6.8634e-02 1.0207e+00 8.0317e-02 1.0813e+00 8.5492e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 152: 1.0321e+02 -4.1291e+00 -2.2281e+00 -4.0180e+00 -1.0232e+00 -1.4990e-01 1.6327e+00 2.8585e-03 1.0498e-01 1.8944e-02 1.6146e-01 5.0784e-02 9.5663e-01 7.9113e-02 1.1344e+00 8.2687e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 153: 1.0309e+02 -4.1280e+00 -2.2030e+00 -4.0149e+00 -1.0198e+00 -1.3442e-01 1.6757e+00 3.4142e-03 9.0693e-02 2.2471e-02 1.6167e-01 3.6279e-02 9.6659e-01 8.1655e-02 1.0345e+00 8.6113e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 154: 1.0298e+02 -4.1506e+00 -2.2176e+00 -3.9851e+00 -1.0417e+00 -1.6429e-01 1.9656e+00 3.3408e-03 9.5697e-02 2.1721e-02 1.6754e-01 2.9142e-02 1.0379e+00 7.9957e-02 1.0132e+00 8.5327e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 155: 1.0328e+02 -4.1204e+00 -2.2287e+00 -3.9772e+00 -1.0135e+00 -2.0459e-01 1.9195e+00 3.3987e-03 1.0293e-01 1.6897e-02 1.9470e-01 2.0826e-02 9.4310e-01 8.0528e-02 1.0639e+00 8.1926e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 156: 1.0338e+02 -4.1272e+00 -2.1962e+00 -3.9743e+00 -1.0491e+00 -1.8971e-01 1.7194e+00 3.2287e-03 7.8468e-02 1.8220e-02 1.8015e-01 2.0956e-02 9.2992e-01 8.6295e-02 9.5939e-01 8.1945e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 157: 1.0331e+02 -4.1188e+00 -2.1783e+00 -3.9779e+00 -1.0506e+00 -1.9810e-01 1.1127e+00 2.7176e-03 6.1234e-02 1.3748e-02 2.0147e-01 3.4800e-02 9.3006e-01 8.4794e-02 1.0579e+00 8.1604e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 158: 1.0326e+02 -4.1162e+00 -2.1734e+00 -3.9827e+00 -1.0632e+00 -2.0171e-01 1.3289e+00 2.7407e-03 7.1465e-02 1.2306e-02 2.1511e-01 3.4923e-02 8.9200e-01 8.4554e-02 1.1179e+00 8.2301e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 159: 1.0358e+02 -4.1075e+00 -2.2069e+00 -3.9725e+00 -1.0445e+00 -1.8044e-01 1.6656e+00 2.5282e-03 6.4340e-02 1.3587e-02 2.0355e-01 2.7629e-02 8.9557e-01 8.3727e-02 1.0560e+00 8.0934e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 160: 1.0364e+02 -4.1182e+00 -2.1514e+00 -3.9750e+00 -1.0378e+00 -2.2449e-01 1.8413e+00 3.5609e-03 7.2072e-02 1.5648e-02 2.0999e-01 3.1283e-02 9.1468e-01 8.2340e-02 1.0016e+00 8.0955e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 161: 1.0387e+02 -4.0964e+00 -2.1926e+00 -3.9808e+00 -1.0397e+00 -2.5178e-01 2.3706e+00 2.4158e-03 7.4658e-02 1.7789e-02 1.8587e-01 3.1647e-02 8.8257e-01 8.4503e-02 9.5909e-01 8.2216e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 162: 1.0399e+02 -4.0992e+00 -2.2056e+00 -3.9647e+00 -1.0388e+00 -2.4824e-01 1.9736e+00 2.2302e-03 1.0445e-01 1.9729e-02 1.9531e-01 2.9879e-02 8.3560e-01 8.6622e-02 9.5407e-01 7.9625e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 163: 1.0366e+02 -4.0956e+00 -2.1684e+00 -3.9612e+00 -1.0058e+00 -2.6882e-01 2.5872e+00 1.6246e-03 8.1892e-02 2.2777e-02 2.2429e-01 2.8371e-02 8.4799e-01 9.0947e-02 9.5842e-01 8.2649e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 164: 1.0325e+02 -4.0878e+00 -2.1946e+00 -3.9781e+00 -9.8890e-01 -2.6917e-01 2.0805e+00 1.3401e-03 8.2477e-02 2.6550e-02 1.8386e-01 2.4255e-02 8.5728e-01 8.9778e-02 9.1439e-01 7.9784e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 165: 1.0282e+02 -4.0801e+00 -2.1928e+00 -3.9664e+00 -9.9558e-01 -2.6059e-01 1.4087e+00 1.2155e-03 5.8081e-02 2.3833e-02 2.1871e-01 2.0911e-02 8.6998e-01 8.9895e-02 9.9363e-01 8.0284e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 166: 1.0285e+02 -4.0942e+00 -2.1855e+00 -3.9889e+00 -1.0234e+00 -2.4125e-01 8.5034e-01 6.8919e-04 6.5725e-02 2.3045e-02 2.1221e-01 2.6083e-02 8.7024e-01 9.4598e-02 9.5824e-01 8.3361e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 167: 1.0267e+02 -4.0904e+00 -2.2131e+00 -3.9917e+00 -9.9055e-01 -2.1449e-01 9.1382e-01 4.6145e-04 8.1337e-02 2.2154e-02 2.1431e-01 2.7524e-02 8.4730e-01 8.3563e-02 9.9458e-01 8.0138e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 168: 1.0249e+02 -4.0954e+00 -2.2174e+00 -3.9868e+00 -9.9799e-01 -1.8848e-01 6.5737e-01 4.2757e-04 6.9428e-02 2.8833e-02 2.0256e-01 4.1573e-02 9.8269e-01 7.6264e-02 1.0011e+00 8.1357e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 169: 1.0252e+02 -4.0995e+00 -2.2132e+00 -3.9792e+00 -9.8661e-01 -2.2724e-01 5.4553e-01 3.9691e-04 4.2460e-02 2.7545e-02 2.2594e-01 4.9079e-02 9.6027e-01 8.1006e-02 1.0261e+00 8.5194e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 170: 1.0246e+02 -4.1056e+00 -2.2389e+00 -3.9785e+00 -1.0354e+00 -2.4212e-01 4.5653e-01 2.8583e-04 2.8936e-02 2.5026e-02 1.8496e-01 4.3514e-02 9.2689e-01 9.6050e-02 9.9096e-01 8.3466e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 171: 1.0238e+02 -4.1027e+00 -2.2592e+00 -3.9859e+00 -1.0106e+00 -2.3962e-01 5.1080e-01 2.6715e-04 3.2138e-02 2.7859e-02 1.6505e-01 6.2560e-02 9.1886e-01 9.0993e-02 9.4634e-01 8.3542e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 172: 1.0242e+02 -4.0998e+00 -2.2415e+00 -3.9999e+00 -1.0234e+00 -2.2610e-01 5.1154e-01 1.8668e-04 2.2768e-02 2.9930e-02 2.0056e-01 7.5570e-02 9.4948e-01 8.4742e-02 9.1357e-01 8.3596e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 173: 1.0232e+02 -4.1005e+00 -2.2382e+00 -4.0022e+00 -1.0017e+00 -1.8406e-01 3.2169e-01 2.0484e-04 2.4102e-02 2.9249e-02 2.0445e-01 1.1517e-01 9.5169e-01 8.3951e-02 9.0402e-01 8.3130e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 174: 1.0233e+02 -4.0990e+00 -2.2337e+00 -3.9975e+00 -1.0298e+00 -1.8028e-01 4.2668e-01 2.1409e-04 2.4350e-02 2.4159e-02 2.0114e-01 1.4344e-01 9.3446e-01 8.6704e-02 9.6511e-01 8.3994e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 175: 1.0236e+02 -4.0991e+00 -2.2315e+00 -3.9883e+00 -1.0110e+00 -2.2190e-01 4.1564e-01 2.5844e-04 3.5664e-02 2.1844e-02 2.0315e-01 1.2876e-01 8.9006e-01 8.3016e-02 9.2369e-01 8.0410e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 176: 1.0222e+02 -4.0983e+00 -2.1991e+00 -3.9924e+00 -1.0148e+00 -2.3133e-01 1.7684e-01 2.5312e-04 5.3516e-02 2.2568e-02 2.0010e-01 1.0721e-01 8.9884e-01 7.6042e-02 1.0110e+00 7.9890e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 177: 1.0219e+02 -4.1022e+00 -2.2129e+00 -3.9804e+00 -1.0286e+00 -1.9916e-01 1.9962e-01 3.0338e-04 6.9476e-02 2.0133e-02 1.8707e-01 1.0631e-01 8.7419e-01 8.3199e-02 9.5450e-01 8.2626e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 178: 1.0225e+02 -4.1022e+00 -2.2135e+00 -4.0057e+00 -1.0264e+00 -2.2859e-01 2.1742e-01 2.9489e-04 5.1238e-02 2.2227e-02 1.7924e-01 1.4496e-01 8.5487e-01 8.3885e-02 9.7315e-01 8.1406e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 179: 1.0234e+02 -4.1015e+00 -2.2170e+00 -3.9999e+00 -1.0177e+00 -2.0895e-01 2.1196e-01 3.0802e-04 5.7417e-02 2.6776e-02 1.7214e-01 1.5197e-01 8.8641e-01 7.7789e-02 9.2725e-01 8.1277e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 180: 1.0243e+02 -4.1034e+00 -2.2337e+00 -4.0000e+00 -1.0018e+00 -2.3492e-01 2.0521e-01 3.1261e-04 6.0162e-02 2.7277e-02 1.7524e-01 1.6673e-01 8.8472e-01 7.8939e-02 9.1311e-01 8.3794e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 181: 1.0244e+02 -4.1031e+00 -2.2415e+00 -3.9951e+00 -9.9356e-01 -1.9938e-01 1.4850e-01 2.7894e-04 5.5244e-02 3.2404e-02 2.0701e-01 2.1022e-01 8.7495e-01 8.1883e-02 9.7574e-01 8.4575e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 182: 1.0245e+02 -4.1066e+00 -2.2849e+00 -4.0083e+00 -1.0260e+00 -1.9418e-01 1.0783e-01 1.7359e-04 2.9632e-02 3.2098e-02 2.0294e-01 1.7919e-01 9.0795e-01 9.1179e-02 9.8651e-01 8.3561e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 183: 1.0248e+02 -4.1066e+00 -2.2844e+00 -4.0201e+00 -1.0102e+00 -1.5510e-01 9.2727e-02 1.4337e-04 2.8436e-02 4.3941e-02 1.9683e-01 2.1943e-01 9.0334e-01 8.2113e-02 8.9037e-01 8.4506e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 184: 1.0239e+02 -4.1032e+00 -2.2726e+00 -4.0270e+00 -1.0162e+00 -1.4921e-01 9.0062e-02 1.0820e-04 3.5099e-02 4.7338e-02 1.8488e-01 2.2174e-01 9.1525e-01 7.9986e-02 8.6762e-01 8.4376e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 185: 1.0240e+02 -4.1028e+00 -2.3201e+00 -4.0248e+00 -9.8758e-01 -1.7235e-01 9.2455e-02 8.9653e-05 4.7097e-02 4.5964e-02 1.9093e-01 1.9093e-01 9.5192e-01 7.6980e-02 9.4058e-01 8.2740e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 186: 1.0250e+02 -4.1020e+00 -2.3095e+00 -4.0326e+00 -9.9767e-01 -1.2041e-01 1.0792e-01 7.3472e-05 3.6352e-02 4.6680e-02 1.7527e-01 1.7411e-01 9.6831e-01 8.3088e-02 9.7978e-01 8.1096e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 187: 1.0254e+02 -4.1022e+00 -2.3078e+00 -4.0329e+00 -1.0166e+00 -1.1644e-01 8.2987e-02 7.9222e-05 3.8388e-02 6.0452e-02 2.3498e-01 1.7389e-01 1.0450e+00 8.0354e-02 9.7366e-01 8.2504e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 188: 1.0253e+02 -4.1022e+00 -2.3172e+00 -4.0401e+00 -1.0276e+00 -8.2442e-02 8.3913e-02 7.1884e-05 4.3025e-02 4.8383e-02 1.9392e-01 1.6073e-01 9.7466e-01 7.5977e-02 9.0319e-01 8.4648e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 189: 1.0256e+02 -4.1013e+00 -2.3037e+00 -4.0402e+00 -1.0004e+00 -1.5946e-01 9.6273e-02 8.0773e-05 4.6130e-02 5.2356e-02 2.1044e-01 2.0403e-01 9.2931e-01 8.2686e-02 9.0103e-01 8.5442e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 190: 1.0245e+02 -4.1021e+00 -2.3143e+00 -4.0314e+00 -9.9314e-01 -8.5545e-02 8.0660e-02 7.3369e-05 4.1713e-02 4.4940e-02 1.7715e-01 1.6886e-01 9.7982e-01 8.1720e-02 8.9868e-01 8.4964e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 191: 1.0251e+02 -4.1021e+00 -2.2849e+00 -4.0229e+00 -1.0346e+00 -9.0261e-02 6.1956e-02 9.4824e-05 5.8037e-02 4.0685e-02 1.8455e-01 2.2838e-01 9.9679e-01 7.7457e-02 9.4591e-01 8.5446e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 192: 1.0249e+02 -4.1012e+00 -2.2915e+00 -4.0452e+00 -1.0323e+00 -1.1123e-01 5.1409e-02 1.1452e-04 7.2457e-02 3.6376e-02 1.6706e-01 2.1050e-01 8.7970e-01 8.6881e-02 9.2230e-01 8.6563e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 193: 1.0249e+02 -4.1011e+00 -2.3104e+00 -4.0569e+00 -1.0032e+00 -2.9383e-02 4.2462e-02 9.6872e-05 4.9405e-02 4.6840e-02 1.7348e-01 1.4473e-01 9.1758e-01 8.1380e-02 1.0057e+00 8.4481e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 194: 1.0250e+02 -4.1009e+00 -2.2960e+00 -4.0567e+00 -9.9145e-01 -1.0640e-01 2.6698e-02 5.3298e-05 4.3880e-02 5.1866e-02 2.0619e-01 1.4008e-01 9.8306e-01 8.0320e-02 9.8405e-01 8.0106e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 195: 1.0252e+02 -4.1001e+00 -2.2779e+00 -4.0677e+00 -9.9960e-01 -5.5605e-02 1.9114e-02 5.6472e-05 4.5810e-02 5.1552e-02 1.8363e-01 1.2037e-01 9.9334e-01 8.2093e-02 9.9128e-01 8.3930e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 196: 1.0251e+02 -4.0988e+00 -2.2515e+00 -4.0555e+00 -9.9701e-01 -1.0235e-01 1.3362e-02 3.2648e-05 4.0337e-02 4.4117e-02 1.9469e-01 1.2907e-01 9.1150e-01 8.5071e-02 9.7929e-01 8.2761e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 197: 1.0253e+02 -4.0985e+00 -2.2589e+00 -4.0427e+00 -1.0251e+00 -9.4695e-02 1.7104e-02 2.3125e-05 4.1773e-02 3.3831e-02 2.1013e-01 1.3727e-01 9.1462e-01 8.1836e-02 9.7695e-01 8.1326e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 198: 1.0253e+02 -4.0992e+00 -2.2745e+00 -4.0327e+00 -9.8743e-01 -1.4108e-01 9.3331e-03 2.3064e-05 3.7271e-02 2.7379e-02 2.1190e-01 9.3733e-02 9.0916e-01 8.4247e-02 9.8720e-01 7.7405e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 199: 1.0251e+02 -4.0981e+00 -2.2770e+00 -4.0275e+00 -1.0216e+00 -1.3364e-01 8.3776e-03 2.3195e-05 4.6827e-02 3.2861e-02 1.9817e-01 8.7748e-02 9.1184e-01 8.3773e-02 9.5209e-01 7.9056e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 200: 1.0252e+02 -4.0992e+00 -2.2757e+00 -4.0277e+00 -9.9266e-01 -8.4583e-02 6.8073e-03 2.9414e-05 5.3404e-02 2.5942e-02 1.9915e-01 7.4937e-02 8.7168e-01 8.5197e-02 9.3606e-01 8.0739e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 201: 1.0252e+02 -4.0989e+00 -2.2706e+00 -4.0333e+00 -9.8978e-01 -8.7996e-02 5.9272e-03 2.4268e-05 5.4295e-02 2.9276e-02 2.0543e-01 7.1533e-02 9.0557e-01 8.3204e-02 9.4913e-01 8.0398e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 202: 1.0251e+02 -4.0990e+00 -2.2661e+00 -4.0324e+00 -9.8785e-01 -9.8008e-02 5.7831e-03 2.1967e-05 5.7627e-02 3.0606e-02 2.1414e-01 6.9475e-02 9.2255e-01 8.2143e-02 9.5633e-01 8.1333e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 203: 1.0251e+02 -4.0992e+00 -2.2586e+00 -4.0297e+00 -9.9017e-01 -1.1012e-01 6.4046e-03 2.2234e-05 5.7955e-02 3.0102e-02 2.0473e-01 6.8225e-02 9.2900e-01 8.3228e-02 9.5862e-01 8.1460e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 204: 1.0251e+02 -4.0995e+00 -2.2570e+00 -4.0280e+00 -9.9135e-01 -1.0718e-01 6.5386e-03 2.2043e-05 5.6949e-02 2.9096e-02 2.0562e-01 6.8687e-02 9.3306e-01 8.2703e-02 9.6581e-01 8.1671e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 205: 1.0250e+02 -4.0997e+00 -2.2569e+00 -4.0256e+00 -9.9350e-01 -1.1491e-01 6.1521e-03 2.2570e-05 5.5450e-02 2.8152e-02 2.0423e-01 7.2820e-02 9.2469e-01 8.3272e-02 9.7372e-01 8.0814e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 206: 1.0250e+02 -4.0997e+00 -2.2567e+00 -4.0269e+00 -9.9869e-01 -1.1438e-01 5.9720e-03 2.3307e-05 5.5103e-02 2.8506e-02 2.0414e-01 7.8225e-02 9.2768e-01 8.3328e-02 9.8294e-01 8.0918e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 207: 1.0250e+02 -4.0998e+00 -2.2657e+00 -4.0311e+00 -1.0000e+00 -1.0595e-01 6.0030e-03 2.4031e-05 5.4378e-02 2.9468e-02 2.0222e-01 8.1455e-02 9.3397e-01 8.3285e-02 9.8989e-01 8.0967e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 208: 1.0250e+02 -4.0999e+00 -2.2759e+00 -4.0330e+00 -1.0001e+00 -9.6916e-02 5.9586e-03 2.3690e-05 5.3811e-02 2.9674e-02 1.9979e-01 8.1206e-02 9.3593e-01 8.4094e-02 9.8891e-01 8.1107e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 209: 1.0250e+02 -4.0998e+00 -2.2836e+00 -4.0344e+00 -1.0016e+00 -8.9119e-02 5.6137e-03 2.3512e-05 5.4159e-02 2.9780e-02 1.9778e-01 8.2635e-02 9.4080e-01 8.3757e-02 9.9062e-01 8.0979e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 210: 1.0251e+02 -4.0998e+00 -2.2898e+00 -4.0334e+00 -1.0017e+00 -8.3861e-02 5.2428e-03 2.3117e-05 5.4271e-02 2.9112e-02 1.9539e-01 8.3602e-02 9.4410e-01 8.4262e-02 9.8944e-01 8.1260e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 211: 1.0251e+02 -4.0998e+00 -2.2968e+00 -4.0329e+00 -9.9953e-01 -8.2036e-02 4.9312e-03 2.2863e-05 5.5392e-02 2.8432e-02 1.9466e-01 8.3724e-02 9.5395e-01 8.4317e-02 9.9876e-01 8.1402e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 212: 1.0251e+02 -4.0997e+00 -2.2982e+00 -4.0327e+00 -1.0018e+00 -8.2942e-02 4.6622e-03 2.3364e-05 5.5864e-02 2.7552e-02 1.9313e-01 8.3815e-02 9.5374e-01 8.4223e-02 1.0049e+00 8.1479e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 213: 1.0251e+02 -4.0995e+00 -2.2996e+00 -4.0322e+00 -1.0027e+00 -8.4931e-02 4.4988e-03 2.4085e-05 5.6000e-02 2.6729e-02 1.9184e-01 8.3522e-02 9.5091e-01 8.4321e-02 1.0026e+00 8.1310e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 214: 1.0251e+02 -4.0994e+00 -2.2997e+00 -4.0326e+00 -1.0033e+00 -8.7810e-02 4.3582e-03 2.5253e-05 5.6470e-02 2.6179e-02 1.9110e-01 8.5338e-02 9.5311e-01 8.4118e-02 1.0062e+00 8.1320e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 215: 1.0251e+02 -4.0993e+00 -2.3013e+00 -4.0331e+00 -1.0042e+00 -8.5053e-02 4.3765e-03 2.6370e-05 5.6978e-02 2.5984e-02 1.8960e-01 8.6633e-02 9.5505e-01 8.3787e-02 1.0092e+00 8.1298e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 216: 1.0251e+02 -4.0993e+00 -2.3032e+00 -4.0320e+00 -1.0033e+00 -8.5521e-02 4.4127e-03 2.7607e-05 5.7092e-02 2.5514e-02 1.8916e-01 8.8986e-02 9.5571e-01 8.3655e-02 1.0106e+00 8.1177e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 217: 1.0251e+02 -4.0993e+00 -2.3050e+00 -4.0309e+00 -1.0039e+00 -8.5267e-02 4.4663e-03 2.8101e-05 5.7536e-02 2.5186e-02 1.8803e-01 9.0776e-02 9.5624e-01 8.3792e-02 1.0100e+00 8.1214e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 218: 1.0251e+02 -4.0993e+00 -2.3068e+00 -4.0309e+00 -1.0052e+00 -8.3353e-02 4.4833e-03 2.7541e-05 5.7391e-02 2.4589e-02 1.8691e-01 9.4302e-02 9.5168e-01 8.4114e-02 1.0124e+00 8.1211e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 219: 1.0251e+02 -4.0993e+00 -2.3077e+00 -4.0316e+00 -1.0049e+00 -8.0885e-02 4.4529e-03 2.6825e-05 5.7273e-02 2.3909e-02 1.8700e-01 9.6040e-02 9.4675e-01 8.4115e-02 1.0115e+00 8.1075e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 220: 1.0251e+02 -4.0993e+00 -2.3095e+00 -4.0327e+00 -1.0051e+00 -7.6386e-02 4.5217e-03 2.6724e-05 5.7342e-02 2.3648e-02 1.8752e-01 9.7466e-02 9.4316e-01 8.4134e-02 1.0099e+00 8.1206e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 221: 1.0251e+02 -4.0993e+00 -2.3120e+00 -4.0339e+00 -1.0050e+00 -7.3314e-02 4.5361e-03 2.6133e-05 5.7387e-02 2.3612e-02 1.8744e-01 9.9108e-02 9.4164e-01 8.4073e-02 1.0096e+00 8.1143e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 222: 1.0251e+02 -4.0993e+00 -2.3136e+00 -4.0355e+00 -1.0049e+00 -6.8041e-02 4.5806e-03 2.5728e-05 5.7827e-02 2.3466e-02 1.8681e-01 9.9150e-02 9.4237e-01 8.3991e-02 1.0116e+00 8.1192e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 223: 1.0251e+02 -4.0993e+00 -2.3144e+00 -4.0364e+00 -1.0047e+00 -6.6770e-02 4.5349e-03 2.5412e-05 5.8823e-02 2.3232e-02 1.8728e-01 9.9882e-02 9.4051e-01 8.3808e-02 1.0097e+00 8.1028e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 224: 1.0251e+02 -4.0992e+00 -2.3155e+00 -4.0373e+00 -1.0040e+00 -6.4487e-02 4.4985e-03 2.5094e-05 6.0294e-02 2.3022e-02 1.8652e-01 1.0114e-01 9.3800e-01 8.3696e-02 1.0099e+00 8.0990e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 225: 1.0251e+02 -4.0992e+00 -2.3167e+00 -4.0384e+00 -1.0041e+00 -6.2966e-02 4.4783e-03 2.4741e-05 6.0569e-02 2.2900e-02 1.8622e-01 1.0072e-01 9.3574e-01 8.3833e-02 1.0075e+00 8.0893e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 226: 1.0251e+02 -4.0993e+00 -2.3173e+00 -4.0395e+00 -1.0036e+00 -6.0541e-02 4.4466e-03 2.4601e-05 6.0661e-02 2.2897e-02 1.8544e-01 1.0160e-01 9.3842e-01 8.3565e-02 1.0064e+00 8.1006e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 227: 1.0251e+02 -4.0993e+00 -2.3183e+00 -4.0403e+00 -1.0028e+00 -5.9061e-02 4.4290e-03 2.4610e-05 6.1093e-02 2.2836e-02 1.8582e-01 1.0184e-01 9.3983e-01 8.3421e-02 1.0066e+00 8.1225e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 228: 1.0251e+02 -4.0993e+00 -2.3190e+00 -4.0405e+00 -1.0027e+00 -5.8994e-02 4.4377e-03 2.4228e-05 6.0957e-02 2.2540e-02 1.8424e-01 1.0104e-01 9.4056e-01 8.3559e-02 1.0085e+00 8.1266e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 229: 1.0251e+02 -4.0993e+00 -2.3206e+00 -4.0398e+00 -1.0026e+00 -5.9258e-02 4.5021e-03 2.3801e-05 6.0331e-02 2.2380e-02 1.8409e-01 9.9681e-02 9.4320e-01 8.3678e-02 1.0111e+00 8.1236e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 230: 1.0251e+02 -4.0994e+00 -2.3217e+00 -4.0401e+00 -1.0028e+00 -5.7766e-02 4.5320e-03 2.3519e-05 5.9913e-02 2.2317e-02 1.8484e-01 9.9325e-02 9.4418e-01 8.3884e-02 1.0144e+00 8.1294e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 231: 1.0251e+02 -4.0994e+00 -2.3223e+00 -4.0400e+00 -1.0036e+00 -5.7213e-02 4.6519e-03 2.3658e-05 5.9386e-02 2.2185e-02 1.8526e-01 9.8374e-02 9.4356e-01 8.4167e-02 1.0171e+00 8.1315e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 232: 1.0251e+02 -4.0994e+00 -2.3231e+00 -4.0400e+00 -1.0045e+00 -5.5248e-02 4.7067e-03 2.3117e-05 5.9583e-02 2.2248e-02 1.8574e-01 9.7396e-02 9.4340e-01 8.4212e-02 1.0179e+00 8.1401e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 233: 1.0251e+02 -4.0994e+00 -2.3237e+00 -4.0401e+00 -1.0046e+00 -5.4085e-02 4.7534e-03 2.2858e-05 5.8985e-02 2.2248e-02 1.8649e-01 9.7364e-02 9.4271e-01 8.4248e-02 1.0189e+00 8.1456e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 234: 1.0251e+02 -4.0995e+00 -2.3238e+00 -4.0400e+00 -1.0042e+00 -5.2957e-02 4.8433e-03 2.2715e-05 5.8868e-02 2.2174e-02 1.8630e-01 9.7975e-02 9.4382e-01 8.4160e-02 1.0210e+00 8.1665e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 235: 1.0251e+02 -4.0995e+00 -2.3248e+00 -4.0396e+00 -1.0044e+00 -5.3132e-02 4.8769e-03 2.2540e-05 5.9052e-02 2.2120e-02 1.8627e-01 9.8772e-02 9.4330e-01 8.4170e-02 1.0196e+00 8.1627e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 236: 1.0251e+02 -4.0995e+00 -2.3244e+00 -4.0392e+00 -1.0052e+00 -5.3786e-02 4.8860e-03 2.2664e-05 5.8981e-02 2.2095e-02 1.8771e-01 9.8852e-02 9.4172e-01 8.4214e-02 1.0191e+00 8.1698e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 237: 1.0251e+02 -4.0996e+00 -2.3231e+00 -4.0386e+00 -1.0056e+00 -5.5158e-02 4.8731e-03 2.2576e-05 5.8788e-02 2.2037e-02 1.8860e-01 9.9599e-02 9.4242e-01 8.4097e-02 1.0198e+00 8.1684e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 238: 1.0251e+02 -4.0996e+00 -2.3222e+00 -4.0384e+00 -1.0054e+00 -5.6412e-02 4.8673e-03 2.2575e-05 5.8733e-02 2.1962e-02 1.8874e-01 9.9196e-02 9.4097e-01 8.4103e-02 1.0208e+00 8.1649e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 239: 1.0251e+02 -4.0996e+00 -2.3212e+00 -4.0382e+00 -1.0068e+00 -5.7131e-02 4.8223e-03 2.2398e-05 5.8674e-02 2.1817e-02 1.8926e-01 9.9323e-02 9.4261e-01 8.4059e-02 1.0229e+00 8.1670e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 240: 1.0251e+02 -4.0996e+00 -2.3216e+00 -4.0376e+00 -1.0073e+00 -5.6962e-02 4.7984e-03 2.2260e-05 5.8558e-02 2.1632e-02 1.8892e-01 9.9232e-02 9.4434e-01 8.4130e-02 1.0237e+00 8.1679e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 241: 1.0251e+02 -4.0996e+00 -2.3216e+00 -4.0371e+00 -1.0078e+00 -5.6984e-02 4.7767e-03 2.2074e-05 5.9552e-02 2.1436e-02 1.8860e-01 9.9285e-02 9.4491e-01 8.4026e-02 1.0247e+00 8.1680e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 242: 1.0251e+02 -4.0996e+00 -2.3222e+00 -4.0372e+00 -1.0079e+00 -5.6422e-02 4.7880e-03 2.2014e-05 6.0033e-02 2.1277e-02 1.8860e-01 9.8674e-02 9.4359e-01 8.3991e-02 1.0255e+00 8.1634e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 243: 1.0251e+02 -4.0995e+00 -2.3227e+00 -4.0376e+00 -1.0079e+00 -5.4330e-02 4.7944e-03 2.1687e-05 6.0189e-02 2.1088e-02 1.8830e-01 9.7952e-02 9.4207e-01 8.4036e-02 1.0257e+00 8.1666e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 244: 1.0251e+02 -4.0995e+00 -2.3237e+00 -4.0385e+00 -1.0076e+00 -5.2834e-02 4.7916e-03 2.1467e-05 6.0432e-02 2.1062e-02 1.8810e-01 9.7065e-02 9.4039e-01 8.4075e-02 1.0248e+00 8.1599e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 245: 1.0251e+02 -4.0995e+00 -2.3249e+00 -4.0390e+00 -1.0073e+00 -5.0542e-02 4.7926e-03 2.1549e-05 6.1095e-02 2.0981e-02 1.8814e-01 9.6715e-02 9.3900e-01 8.4049e-02 1.0226e+00 8.1505e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 246: 1.0251e+02 -4.0995e+00 -2.3261e+00 -4.0398e+00 -1.0066e+00 -4.7686e-02 4.8114e-03 2.1557e-05 6.1692e-02 2.0969e-02 1.8783e-01 9.6477e-02 9.3880e-01 8.4024e-02 1.0211e+00 8.1456e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 247: 1.0251e+02 -4.0996e+00 -2.3270e+00 -4.0406e+00 -1.0063e+00 -4.5794e-02 4.7864e-03 2.1709e-05 6.1819e-02 2.0928e-02 1.8765e-01 9.5549e-02 9.3939e-01 8.4076e-02 1.0201e+00 8.1427e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 248: 1.0251e+02 -4.0995e+00 -2.3282e+00 -4.0412e+00 -1.0064e+00 -4.3009e-02 4.7307e-03 2.1707e-05 6.2309e-02 2.0970e-02 1.8795e-01 9.5221e-02 9.3898e-01 8.4080e-02 1.0197e+00 8.1501e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 249: 1.0251e+02 -4.0996e+00 -2.3298e+00 -4.0417e+00 -1.0070e+00 -4.1062e-02 4.7070e-03 2.1737e-05 6.2607e-02 2.1094e-02 1.8796e-01 9.5103e-02 9.3917e-01 8.4069e-02 1.0194e+00 8.1525e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 250: 1.0251e+02 -4.0996e+00 -2.3313e+00 -4.0420e+00 -1.0073e+00 -3.9250e-02 4.7191e-03 2.1947e-05 6.2963e-02 2.1053e-02 1.8834e-01 9.4954e-02 9.3851e-01 8.4115e-02 1.0190e+00 8.1496e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 251: 1.0251e+02 -4.0997e+00 -2.3317e+00 -4.0424e+00 -1.0078e+00 -3.7549e-02 4.7501e-03 2.2063e-05 6.3160e-02 2.0958e-02 1.8840e-01 9.4783e-02 9.3749e-01 8.4137e-02 1.0185e+00 8.1476e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 252: 1.0251e+02 -4.0997e+00 -2.3319e+00 -4.0424e+00 -1.0083e+00 -3.6657e-02 4.7441e-03 2.2081e-05 6.3250e-02 2.0891e-02 1.8911e-01 9.4954e-02 9.3708e-01 8.4108e-02 1.0180e+00 8.1479e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 253: 1.0251e+02 -4.0997e+00 -2.3323e+00 -4.0425e+00 -1.0085e+00 -3.5826e-02 4.7409e-03 2.2021e-05 6.3513e-02 2.0810e-02 1.8920e-01 9.5196e-02 9.3509e-01 8.4179e-02 1.0184e+00 8.1440e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 254: 1.0251e+02 -4.0997e+00 -2.3324e+00 -4.0426e+00 -1.0086e+00 -3.6456e-02 4.7046e-03 2.1929e-05 6.3535e-02 2.0859e-02 1.9010e-01 9.5077e-02 9.3362e-01 8.4279e-02 1.0185e+00 8.1371e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 255: 1.0251e+02 -4.0997e+00 -2.3313e+00 -4.0424e+00 -1.0088e+00 -3.7358e-02 4.6636e-03 2.1827e-05 6.3864e-02 2.0820e-02 1.9126e-01 9.4979e-02 9.3183e-01 8.4380e-02 1.0185e+00 8.1434e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 256: 1.0251e+02 -4.0997e+00 -2.3306e+00 -4.0423e+00 -1.0086e+00 -3.8558e-02 4.6418e-03 2.1776e-05 6.4176e-02 2.0845e-02 1.9175e-01 9.4890e-02 9.3144e-01 8.4436e-02 1.0188e+00 8.1420e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 257: 1.0251e+02 -4.0997e+00 -2.3297e+00 -4.0419e+00 -1.0092e+00 -3.9580e-02 4.6134e-03 2.1742e-05 6.4408e-02 2.0751e-02 1.9188e-01 9.4692e-02 9.3113e-01 8.4507e-02 1.0187e+00 8.1412e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 258: 1.0251e+02 -4.0997e+00 -2.3287e+00 -4.0415e+00 -1.0090e+00 -4.0619e-02 4.5918e-03 2.1710e-05 6.4634e-02 2.0663e-02 1.9172e-01 9.4422e-02 9.3104e-01 8.4479e-02 1.0189e+00 8.1395e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 259: 1.0251e+02 -4.0997e+00 -2.3284e+00 -4.0412e+00 -1.0086e+00 -4.1245e-02 4.5889e-03 2.1741e-05 6.5035e-02 2.0678e-02 1.9132e-01 9.3998e-02 9.2986e-01 8.4448e-02 1.0177e+00 8.1368e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 260: 1.0251e+02 -4.0997e+00 -2.3283e+00 -4.0410e+00 -1.0084e+00 -4.1907e-02 4.5818e-03 2.1877e-05 6.5755e-02 2.0691e-02 1.9113e-01 9.3631e-02 9.2955e-01 8.4378e-02 1.0172e+00 8.1346e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 261: 1.0251e+02 -4.0998e+00 -2.3282e+00 -4.0409e+00 -1.0087e+00 -4.2022e-02 4.5724e-03 2.1946e-05 6.6396e-02 2.0714e-02 1.9084e-01 9.3140e-02 9.2882e-01 8.4426e-02 1.0166e+00 8.1329e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 262: 1.0251e+02 -4.0997e+00 -2.3275e+00 -4.0408e+00 -1.0092e+00 -4.2439e-02 4.5357e-03 2.1842e-05 6.6895e-02 2.0692e-02 1.9082e-01 9.2527e-02 9.2811e-01 8.4447e-02 1.0168e+00 8.1339e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 263: 1.0251e+02 -4.0998e+00 -2.3269e+00 -4.0407e+00 -1.0097e+00 -4.2867e-02 4.5244e-03 2.1830e-05 6.7068e-02 2.0721e-02 1.9077e-01 9.2003e-02 9.2800e-01 8.4366e-02 1.0171e+00 8.1343e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 264: 1.0251e+02 -4.0998e+00 -2.3262e+00 -4.0403e+00 -1.0102e+00 -4.3066e-02 4.4987e-03 2.1812e-05 6.7458e-02 2.0718e-02 1.9065e-01 9.1528e-02 9.2710e-01 8.4389e-02 1.0163e+00 8.1355e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 265: 1.0251e+02 -4.0998e+00 -2.3264e+00 -4.0401e+00 -1.0105e+00 -4.3042e-02 4.4865e-03 2.1721e-05 6.7680e-02 2.0722e-02 1.9057e-01 9.1243e-02 9.2631e-01 8.4430e-02 1.0154e+00 8.1321e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 266: 1.0251e+02 -4.0998e+00 -2.3264e+00 -4.0397e+00 -1.0107e+00 -4.3247e-02 4.4552e-03 2.1609e-05 6.8246e-02 2.0757e-02 1.9054e-01 9.1222e-02 9.2659e-01 8.4381e-02 1.0154e+00 8.1290e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 267: 1.0251e+02 -4.0999e+00 -2.3261e+00 -4.0396e+00 -1.0107e+00 -4.4145e-02 4.4367e-03 2.1505e-05 6.8834e-02 2.0735e-02 1.9038e-01 9.1594e-02 9.2661e-01 8.4338e-02 1.0153e+00 8.1308e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 268: 1.0251e+02 -4.0999e+00 -2.3249e+00 -4.0395e+00 -1.0112e+00 -4.5394e-02 4.4239e-03 2.1411e-05 6.9776e-02 2.0749e-02 1.9017e-01 9.1916e-02 9.2711e-01 8.4286e-02 1.0158e+00 8.1400e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 269: 1.0251e+02 -4.0999e+00 -2.3236e+00 -4.0391e+00 -1.0112e+00 -4.6744e-02 4.4119e-03 2.1310e-05 7.0528e-02 2.0709e-02 1.9026e-01 9.2008e-02 9.2638e-01 8.4248e-02 1.0160e+00 8.1389e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 270: 1.0251e+02 -4.0999e+00 -2.3231e+00 -4.0388e+00 -1.0116e+00 -4.7514e-02 4.3782e-03 2.1160e-05 7.1513e-02 2.0724e-02 1.9006e-01 9.1551e-02 9.2668e-01 8.4246e-02 1.0149e+00 8.1419e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 271: 1.0251e+02 -4.0999e+00 -2.3228e+00 -4.0387e+00 -1.0117e+00 -4.7755e-02 4.3389e-03 2.1121e-05 7.1868e-02 2.0670e-02 1.8969e-01 9.1369e-02 9.2678e-01 8.4228e-02 1.0145e+00 8.1437e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 272: 1.0251e+02 -4.0999e+00 -2.3222e+00 -4.0387e+00 -1.0121e+00 -4.8163e-02 4.3080e-03 2.1146e-05 7.2226e-02 2.0710e-02 1.8983e-01 9.0962e-02 9.2639e-01 8.4261e-02 1.0132e+00 8.1523e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 273: 1.0251e+02 -4.0999e+00 -2.3216e+00 -4.0389e+00 -1.0122e+00 -4.8336e-02 4.2916e-03 2.1202e-05 7.2734e-02 2.0689e-02 1.8982e-01 9.0422e-02 9.2618e-01 8.4177e-02 1.0134e+00 8.1561e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 274: 1.0251e+02 -4.0999e+00 -2.3211e+00 -4.0388e+00 -1.0124e+00 -4.8286e-02 4.2592e-03 2.1201e-05 7.3324e-02 2.0658e-02 1.9015e-01 8.9938e-02 9.2530e-01 8.4133e-02 1.0133e+00 8.1562e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 275: 1.0251e+02 -4.0999e+00 -2.3211e+00 -4.0387e+00 -1.0128e+00 -4.8312e-02 4.2368e-03 2.1092e-05 7.3673e-02 2.0639e-02 1.9018e-01 8.9708e-02 9.2404e-01 8.4155e-02 1.0130e+00 8.1535e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 276: 1.0251e+02 -4.0999e+00 -2.3212e+00 -4.0386e+00 -1.0126e+00 -4.8249e-02 4.2070e-03 2.0985e-05 7.4089e-02 2.0674e-02 1.8992e-01 8.9341e-02 9.2339e-01 8.4163e-02 1.0121e+00 8.1515e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 277: 1.0251e+02 -4.0999e+00 -2.3212e+00 -4.0387e+00 -1.0123e+00 -4.8743e-02 4.1781e-03 2.0914e-05 7.4488e-02 2.0779e-02 1.8959e-01 8.9106e-02 9.2352e-01 8.4100e-02 1.0112e+00 8.1477e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 278: 1.0251e+02 -4.0999e+00 -2.3213e+00 -4.0385e+00 -1.0118e+00 -4.9468e-02 4.1782e-03 2.0802e-05 7.4843e-02 2.0859e-02 1.8970e-01 8.8995e-02 9.2374e-01 8.4037e-02 1.0103e+00 8.1458e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 279: 1.0251e+02 -4.0999e+00 -2.3213e+00 -4.0384e+00 -1.0115e+00 -4.9612e-02 4.1736e-03 2.0737e-05 7.5385e-02 2.0899e-02 1.8969e-01 8.8806e-02 9.2347e-01 8.3989e-02 1.0095e+00 8.1440e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 280: 1.0251e+02 -4.0999e+00 -2.3213e+00 -4.0382e+00 -1.0114e+00 -5.0460e-02 4.1900e-03 2.0708e-05 7.6051e-02 2.0933e-02 1.8968e-01 8.9243e-02 9.2293e-01 8.3972e-02 1.0085e+00 8.1467e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 281: 1.0251e+02 -4.0999e+00 -2.3215e+00 -4.0378e+00 -1.0113e+00 -5.0583e-02 4.2096e-03 2.0638e-05 7.6759e-02 2.1003e-02 1.8941e-01 8.9450e-02 9.2294e-01 8.4027e-02 1.0080e+00 8.1467e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 282: 1.0251e+02 -4.0999e+00 -2.3218e+00 -4.0380e+00 -1.0114e+00 -5.0276e-02 4.2061e-03 2.0669e-05 7.7323e-02 2.1016e-02 1.8946e-01 8.9456e-02 9.2386e-01 8.3996e-02 1.0095e+00 8.1446e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 283: 1.0251e+02 -4.0999e+00 -2.3224e+00 -4.0383e+00 -1.0115e+00 -4.9357e-02 4.2005e-03 2.0601e-05 7.7856e-02 2.1072e-02 1.8968e-01 8.9327e-02 9.2480e-01 8.3964e-02 1.0101e+00 8.1418e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 284: 1.0251e+02 -4.0999e+00 -2.3226e+00 -4.0386e+00 -1.0110e+00 -4.8703e-02 4.1977e-03 2.0549e-05 7.8183e-02 2.1122e-02 1.8956e-01 8.9430e-02 9.2470e-01 8.3898e-02 1.0098e+00 8.1428e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 285: 1.0251e+02 -4.0999e+00 -2.3232e+00 -4.0389e+00 -1.0110e+00 -4.7526e-02 4.2063e-03 2.0546e-05 7.8449e-02 2.1151e-02 1.8967e-01 8.9133e-02 9.2438e-01 8.3889e-02 1.0089e+00 8.1428e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 286: 1.0251e+02 -4.0999e+00 -2.3242e+00 -4.0389e+00 -1.0103e+00 -4.6191e-02 4.2076e-03 2.0486e-05 7.8629e-02 2.1133e-02 1.8970e-01 8.8773e-02 9.2471e-01 8.3861e-02 1.0087e+00 8.1427e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 287: 1.0251e+02 -4.0999e+00 -2.3243e+00 -4.0391e+00 -1.0105e+00 -4.5159e-02 4.1980e-03 2.0488e-05 7.8916e-02 2.1071e-02 1.8955e-01 8.8297e-02 9.2415e-01 8.3957e-02 1.0084e+00 8.1464e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 288: 1.0251e+02 -4.0999e+00 -2.3237e+00 -4.0392e+00 -1.0109e+00 -4.4970e-02 4.1921e-03 2.0495e-05 7.8764e-02 2.0953e-02 1.8988e-01 8.8160e-02 9.2539e-01 8.3963e-02 1.0103e+00 8.1466e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 289: 1.0251e+02 -4.0999e+00 -2.3232e+00 -4.0392e+00 -1.0114e+00 -4.4592e-02 4.1763e-03 2.0584e-05 7.8632e-02 2.0841e-02 1.8982e-01 8.8037e-02 9.2559e-01 8.4031e-02 1.0111e+00 8.1469e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 290: 1.0251e+02 -4.0999e+00 -2.3228e+00 -4.0393e+00 -1.0118e+00 -4.4506e-02 4.1574e-03 2.0479e-05 7.8482e-02 2.0726e-02 1.8968e-01 8.7644e-02 9.2519e-01 8.4079e-02 1.0117e+00 8.1474e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 291: 1.0251e+02 -4.0999e+00 -2.3223e+00 -4.0392e+00 -1.0120e+00 -4.4578e-02 4.1365e-03 2.0488e-05 7.8220e-02 2.0662e-02 1.8952e-01 8.7558e-02 9.2534e-01 8.4128e-02 1.0119e+00 8.1459e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 292: 1.0251e+02 -4.0999e+00 -2.3219e+00 -4.0392e+00 -1.0120e+00 -4.4486e-02 4.1205e-03 2.0514e-05 7.8288e-02 2.0601e-02 1.8947e-01 8.7669e-02 9.2591e-01 8.4106e-02 1.0124e+00 8.1443e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 293: 1.0251e+02 -4.0999e+00 -2.3217e+00 -4.0395e+00 -1.0120e+00 -4.3914e-02 4.1076e-03 2.0606e-05 7.8474e-02 2.0557e-02 1.8960e-01 8.7970e-02 9.2580e-01 8.4052e-02 1.0124e+00 8.1443e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 294: 1.0251e+02 -4.0998e+00 -2.3218e+00 -4.0399e+00 -1.0123e+00 -4.3173e-02 4.1124e-03 2.0598e-05 7.8561e-02 2.0485e-02 1.8979e-01 8.7954e-02 9.2624e-01 8.4027e-02 1.0132e+00 8.1419e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 295: 1.0251e+02 -4.0998e+00 -2.3220e+00 -4.0399e+00 -1.0123e+00 -4.2805e-02 4.1150e-03 2.0599e-05 7.8804e-02 2.0397e-02 1.8985e-01 8.8079e-02 9.2637e-01 8.3980e-02 1.0139e+00 8.1382e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 296: 1.0251e+02 -4.0998e+00 -2.3224e+00 -4.0401e+00 -1.0121e+00 -4.2813e-02 4.1342e-03 2.0618e-05 7.9093e-02 2.0359e-02 1.8980e-01 8.8328e-02 9.2555e-01 8.3955e-02 1.0137e+00 8.1344e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 297: 1.0251e+02 -4.0998e+00 -2.3225e+00 -4.0403e+00 -1.0118e+00 -4.2861e-02 4.1653e-03 2.0599e-05 7.9236e-02 2.0318e-02 1.8969e-01 8.8659e-02 9.2477e-01 8.3916e-02 1.0135e+00 8.1323e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 298: 1.0251e+02 -4.0997e+00 -2.3228e+00 -4.0404e+00 -1.0116e+00 -4.2874e-02 4.2066e-03 2.0567e-05 7.9391e-02 2.0249e-02 1.8973e-01 8.8706e-02 9.2359e-01 8.3939e-02 1.0134e+00 8.1277e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 299: 1.0251e+02 -4.0997e+00 -2.3224e+00 -4.0404e+00 -1.0113e+00 -4.3190e-02 4.2168e-03 2.0532e-05 7.9379e-02 2.0187e-02 1.8973e-01 8.8757e-02 9.2294e-01 8.3916e-02 1.0137e+00 8.1243e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 300: 1.0251e+02 -4.0997e+00 -2.3221e+00 -4.0405e+00 -1.0111e+00 -4.3480e-02 4.2289e-03 2.0490e-05 7.9314e-02 2.0140e-02 1.8983e-01 8.8620e-02 9.2242e-01 8.3900e-02 1.0137e+00 8.1210e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 301: 1.0251e+02 -4.0997e+00 -2.3213e+00 -4.0404e+00 -1.0109e+00 -4.4169e-02 4.2524e-03 2.0546e-05 7.9499e-02 2.0117e-02 1.8991e-01 8.8503e-02 9.2226e-01 8.3843e-02 1.0136e+00 8.1235e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 302: 1.0251e+02 -4.0997e+00 -2.3205e+00 -4.0403e+00 -1.0108e+00 -4.5199e-02 4.2709e-03 2.0511e-05 7.9674e-02 2.0085e-02 1.8969e-01 8.8687e-02 9.2207e-01 8.3852e-02 1.0134e+00 8.1262e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 303: 1.0251e+02 -4.0997e+00 -2.3199e+00 -4.0401e+00 -1.0106e+00 -4.6193e-02 4.2807e-03 2.0440e-05 7.9845e-02 2.0104e-02 1.8985e-01 8.8661e-02 9.2135e-01 8.3843e-02 1.0128e+00 8.1274e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 304: 1.0251e+02 -4.0997e+00 -2.3189e+00 -4.0398e+00 -1.0105e+00 -4.7180e-02 4.3058e-03 2.0450e-05 7.9808e-02 2.0159e-02 1.8987e-01 8.8660e-02 9.2076e-01 8.3856e-02 1.0120e+00 8.1277e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 305: 1.0251e+02 -4.0997e+00 -2.3180e+00 -4.0396e+00 -1.0102e+00 -4.8474e-02 4.3050e-03 2.0527e-05 7.9932e-02 2.0184e-02 1.8970e-01 8.8567e-02 9.1986e-01 8.3867e-02 1.0111e+00 8.1290e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 306: 1.0251e+02 -4.0997e+00 -2.3175e+00 -4.0393e+00 -1.0101e+00 -4.9308e-02 4.3055e-03 2.0586e-05 8.0113e-02 2.0178e-02 1.8971e-01 8.8307e-02 9.1930e-01 8.3865e-02 1.0112e+00 8.1290e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 307: 1.0251e+02 -4.0997e+00 -2.3175e+00 -4.0393e+00 -1.0103e+00 -4.9278e-02 4.3027e-03 2.0441e-05 8.0168e-02 2.0211e-02 1.8973e-01 8.7993e-02 9.1919e-01 8.3837e-02 1.0109e+00 8.1287e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 308: 1.0251e+02 -4.0998e+00 -2.3175e+00 -4.0394e+00 -1.0103e+00 -4.9430e-02 4.2899e-03 2.0384e-05 8.0417e-02 2.0187e-02 1.8983e-01 8.7757e-02 9.1937e-01 8.3778e-02 1.0106e+00 8.1289e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 309: 1.0251e+02 -4.0998e+00 -2.3175e+00 -4.0393e+00 -1.0103e+00 -4.9319e-02 4.2773e-03 2.0349e-05 8.0807e-02 2.0161e-02 1.8959e-01 8.7493e-02 9.1950e-01 8.3734e-02 1.0108e+00 8.1279e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 310: 1.0251e+02 -4.0998e+00 -2.3174e+00 -4.0393e+00 -1.0101e+00 -4.8880e-02 4.2710e-03 2.0327e-05 8.1202e-02 2.0116e-02 1.8983e-01 8.7251e-02 9.1864e-01 8.3730e-02 1.0108e+00 8.1294e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 311: 1.0251e+02 -4.0998e+00 -2.3174e+00 -4.0394e+00 -1.0100e+00 -4.8080e-02 4.2611e-03 2.0272e-05 8.1332e-02 2.0078e-02 1.9003e-01 8.6995e-02 9.1844e-01 8.3699e-02 1.0105e+00 8.1319e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 312: 1.0251e+02 -4.0998e+00 -2.3173e+00 -4.0394e+00 -1.0100e+00 -4.7724e-02 4.2663e-03 2.0239e-05 8.1553e-02 2.0021e-02 1.8982e-01 8.6721e-02 9.1838e-01 8.3721e-02 1.0100e+00 8.1312e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 313: 1.0251e+02 -4.0998e+00 -2.3170e+00 -4.0395e+00 -1.0100e+00 -4.7216e-02 4.2775e-03 2.0213e-05 8.2001e-02 1.9971e-02 1.8980e-01 8.6651e-02 9.1837e-01 8.3697e-02 1.0100e+00 8.1318e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 314: 1.0251e+02 -4.0998e+00 -2.3169e+00 -4.0398e+00 -1.0100e+00 -4.6902e-02 4.2949e-03 2.0265e-05 8.2392e-02 1.9922e-02 1.8988e-01 8.6426e-02 9.1845e-01 8.3722e-02 1.0103e+00 8.1309e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 315: 1.0251e+02 -4.0998e+00 -2.3168e+00 -4.0399e+00 -1.0102e+00 -4.6480e-02 4.3206e-03 2.0314e-05 8.2534e-02 1.9912e-02 1.8972e-01 8.6211e-02 9.1792e-01 8.3758e-02 1.0103e+00 8.1337e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 316: 1.0251e+02 -4.0998e+00 -2.3169e+00 -4.0400e+00 -1.0100e+00 -4.6238e-02 4.3456e-03 2.0323e-05 8.2729e-02 1.9936e-02 1.8975e-01 8.5856e-02 9.1759e-01 8.3814e-02 1.0095e+00 8.1353e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 317: 1.0251e+02 -4.0998e+00 -2.3169e+00 -4.0402e+00 -1.0103e+00 -4.5470e-02 4.3521e-03 2.0275e-05 8.2864e-02 1.9965e-02 1.8980e-01 8.5438e-02 9.1755e-01 8.3894e-02 1.0088e+00 8.1373e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 318: 1.0251e+02 -4.0998e+00 -2.3169e+00 -4.0402e+00 -1.0106e+00 -4.5001e-02 4.3661e-03 2.0191e-05 8.2949e-02 1.9983e-02 1.9001e-01 8.5203e-02 9.1746e-01 8.3944e-02 1.0078e+00 8.1401e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 319: 1.0251e+02 -4.0998e+00 -2.3169e+00 -4.0403e+00 -1.0108e+00 -4.4545e-02 4.3665e-03 2.0114e-05 8.2694e-02 2.0003e-02 1.9041e-01 8.4997e-02 9.1774e-01 8.3940e-02 1.0073e+00 8.1417e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 320: 1.0251e+02 -4.0998e+00 -2.3171e+00 -4.0402e+00 -1.0109e+00 -4.4419e-02 4.3600e-03 2.0043e-05 8.2516e-02 1.9999e-02 1.9044e-01 8.4873e-02 9.1798e-01 8.3932e-02 1.0070e+00 8.1420e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 321: 1.0251e+02 -4.0998e+00 -2.3170e+00 -4.0401e+00 -1.0107e+00 -4.4267e-02 4.3539e-03 1.9995e-05 8.2307e-02 1.9967e-02 1.9050e-01 8.4982e-02 9.1814e-01 8.3919e-02 1.0067e+00 8.1429e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 322: 1.0251e+02 -4.0998e+00 -2.3170e+00 -4.0400e+00 -1.0106e+00 -4.4240e-02 4.3331e-03 1.9984e-05 8.2305e-02 1.9961e-02 1.9054e-01 8.5443e-02 9.1821e-01 8.3910e-02 1.0065e+00 8.1424e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 323: 1.0251e+02 -4.0998e+00 -2.3166e+00 -4.0397e+00 -1.0105e+00 -4.4793e-02 4.3199e-03 1.9921e-05 8.2300e-02 1.9935e-02 1.9078e-01 8.6081e-02 9.1836e-01 8.3854e-02 1.0062e+00 8.1448e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 324: 1.0251e+02 -4.0998e+00 -2.3167e+00 -4.0395e+00 -1.0104e+00 -4.4862e-02 4.3167e-03 1.9926e-05 8.2063e-02 1.9919e-02 1.9086e-01 8.6736e-02 9.1865e-01 8.3834e-02 1.0060e+00 8.1439e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 325: 1.0251e+02 -4.0998e+00 -2.3166e+00 -4.0394e+00 -1.0103e+00 -4.5123e-02 4.3012e-03 1.9902e-05 8.1871e-02 1.9888e-02 1.9103e-01 8.7030e-02 9.1829e-01 8.3865e-02 1.0059e+00 8.1436e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 326: 1.0251e+02 -4.0998e+00 -2.3166e+00 -4.0393e+00 -1.0100e+00 -4.5111e-02 4.2839e-03 1.9869e-05 8.2016e-02 1.9843e-02 1.9083e-01 8.7106e-02 9.1802e-01 8.3847e-02 1.0058e+00 8.1427e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 327: 1.0251e+02 -4.0998e+00 -2.3165e+00 -4.0393e+00 -1.0101e+00 -4.5297e-02 4.2847e-03 1.9858e-05 8.2297e-02 1.9823e-02 1.9075e-01 8.7398e-02 9.1826e-01 8.3771e-02 1.0054e+00 8.1451e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 328: 1.0251e+02 -4.0998e+00 -2.3162e+00 -4.0393e+00 -1.0100e+00 -4.5633e-02 4.2864e-03 1.9877e-05 8.2486e-02 1.9809e-02 1.9060e-01 8.7863e-02 9.1822e-01 8.3706e-02 1.0049e+00 8.1482e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 329: 1.0251e+02 -4.0998e+00 -2.3163e+00 -4.0392e+00 -1.0098e+00 -4.5698e-02 4.3097e-03 1.9869e-05 8.2469e-02 1.9795e-02 1.9047e-01 8.8220e-02 9.1805e-01 8.3704e-02 1.0045e+00 8.1502e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 330: 1.0251e+02 -4.0998e+00 -2.3168e+00 -4.0390e+00 -1.0099e+00 -4.5752e-02 4.3120e-03 1.9810e-05 8.2684e-02 1.9770e-02 1.9049e-01 8.8495e-02 9.1779e-01 8.3731e-02 1.0046e+00 8.1500e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 331: 1.0251e+02 -4.0998e+00 -2.3170e+00 -4.0390e+00 -1.0099e+00 -4.5957e-02 4.3052e-03 1.9736e-05 8.2748e-02 1.9734e-02 1.9034e-01 8.8651e-02 9.1818e-01 8.3707e-02 1.0050e+00 8.1489e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 332: 1.0251e+02 -4.0998e+00 -2.3171e+00 -4.0391e+00 -1.0098e+00 -4.5788e-02 4.2994e-03 1.9733e-05 8.2906e-02 1.9711e-02 1.9035e-01 8.8647e-02 9.1835e-01 8.3660e-02 1.0052e+00 8.1490e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 333: 1.0251e+02 -4.0998e+00 -2.3173e+00 -4.0392e+00 -1.0099e+00 -4.5316e-02 4.2822e-03 1.9667e-05 8.2967e-02 1.9695e-02 1.9041e-01 8.8729e-02 9.1832e-01 8.3666e-02 1.0056e+00 8.1484e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 334: 1.0251e+02 -4.0998e+00 -2.3179e+00 -4.0394e+00 -1.0097e+00 -4.4740e-02 4.2668e-03 1.9593e-05 8.3055e-02 1.9702e-02 1.9058e-01 8.8853e-02 9.1799e-01 8.3687e-02 1.0056e+00 8.1457e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 335: 1.0251e+02 -4.0998e+00 -2.3181e+00 -4.0395e+00 -1.0095e+00 -4.4451e-02 4.2558e-03 1.9535e-05 8.3023e-02 1.9762e-02 1.9027e-01 8.9035e-02 9.1828e-01 8.3673e-02 1.0052e+00 8.1469e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 336: 1.0251e+02 -4.0998e+00 -2.3178e+00 -4.0395e+00 -1.0098e+00 -4.4500e-02 4.2571e-03 1.9546e-05 8.3051e-02 1.9779e-02 1.9024e-01 8.9486e-02 9.1868e-01 8.3611e-02 1.0053e+00 8.1515e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 337: 1.0251e+02 -4.0998e+00 -2.3179e+00 -4.0396e+00 -1.0099e+00 -4.4018e-02 4.2494e-03 1.9584e-05 8.3206e-02 1.9764e-02 1.9011e-01 8.9643e-02 9.1871e-01 8.3659e-02 1.0056e+00 8.1531e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 338: 1.0251e+02 -4.0998e+00 -2.3180e+00 -4.0396e+00 -1.0101e+00 -4.3768e-02 4.2332e-03 1.9635e-05 8.3235e-02 1.9751e-02 1.9011e-01 8.9877e-02 9.1939e-01 8.3622e-02 1.0060e+00 8.1528e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 339: 1.0251e+02 -4.0998e+00 -2.3186e+00 -4.0397e+00 -1.0098e+00 -4.3605e-02 4.2237e-03 1.9638e-05 8.3611e-02 1.9725e-02 1.9014e-01 8.9946e-02 9.2025e-01 8.3580e-02 1.0064e+00 8.1528e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 340: 1.0251e+02 -4.0998e+00 -2.3190e+00 -4.0396e+00 -1.0097e+00 -4.3585e-02 4.2095e-03 1.9630e-05 8.3986e-02 1.9677e-02 1.9019e-01 8.9920e-02 9.2124e-01 8.3559e-02 1.0073e+00 8.1516e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 341: 1.0251e+02 -4.0998e+00 -2.3191e+00 -4.0398e+00 -1.0097e+00 -4.3238e-02 4.1994e-03 1.9636e-05 8.4311e-02 1.9683e-02 1.9023e-01 8.9809e-02 9.2179e-01 8.3517e-02 1.0079e+00 8.1498e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 342: 1.0251e+02 -4.0998e+00 -2.3194e+00 -4.0400e+00 -1.0097e+00 -4.2748e-02 4.1886e-03 1.9661e-05 8.4345e-02 1.9684e-02 1.9018e-01 8.9600e-02 9.2207e-01 8.3517e-02 1.0081e+00 8.1517e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 343: 1.0251e+02 -4.0998e+00 -2.3196e+00 -4.0402e+00 -1.0096e+00 -4.2336e-02 4.1813e-03 1.9615e-05 8.4331e-02 1.9666e-02 1.9016e-01 8.9379e-02 9.2231e-01 8.3534e-02 1.0083e+00 8.1548e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 344: 1.0251e+02 -4.0998e+00 -2.3197e+00 -4.0403e+00 -1.0097e+00 -4.2462e-02 4.1751e-03 1.9621e-05 8.4176e-02 1.9673e-02 1.8996e-01 8.9217e-02 9.2236e-01 8.3540e-02 1.0083e+00 8.1557e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 345: 1.0251e+02 -4.0998e+00 -2.3200e+00 -4.0403e+00 -1.0098e+00 -4.2327e-02 4.1705e-03 1.9552e-05 8.4159e-02 1.9684e-02 1.9017e-01 8.8957e-02 9.2232e-01 8.3511e-02 1.0085e+00 8.1566e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 346: 1.0251e+02 -4.0998e+00 -2.3200e+00 -4.0403e+00 -1.0097e+00 -4.2261e-02 4.1750e-03 1.9564e-05 8.4080e-02 1.9731e-02 1.9047e-01 8.8630e-02 9.2248e-01 8.3516e-02 1.0081e+00 8.1578e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 347: 1.0251e+02 -4.0999e+00 -2.3200e+00 -4.0403e+00 -1.0096e+00 -4.2296e-02 4.1883e-03 1.9634e-05 8.4231e-02 1.9747e-02 1.9061e-01 8.8399e-02 9.2250e-01 8.3557e-02 1.0075e+00 8.1580e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 348: 1.0251e+02 -4.0999e+00 -2.3199e+00 -4.0404e+00 -1.0096e+00 -4.2345e-02 4.2129e-03 1.9692e-05 8.4295e-02 1.9719e-02 1.9068e-01 8.8210e-02 9.2212e-01 8.3568e-02 1.0075e+00 8.1586e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 349: 1.0251e+02 -4.0999e+00 -2.3198e+00 -4.0404e+00 -1.0095e+00 -4.2617e-02 4.2066e-03 1.9720e-05 8.4289e-02 1.9731e-02 1.9054e-01 8.8147e-02 9.2185e-01 8.3565e-02 1.0070e+00 8.1590e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 350: 1.0251e+02 -4.0999e+00 -2.3196e+00 -4.0405e+00 -1.0093e+00 -4.2582e-02 4.2011e-03 1.9760e-05 8.4302e-02 1.9703e-02 1.9044e-01 8.8068e-02 9.2182e-01 8.3537e-02 1.0070e+00 8.1590e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 351: 1.0251e+02 -4.0998e+00 -2.3198e+00 -4.0405e+00 -1.0093e+00 -4.2377e-02 4.1970e-03 1.9750e-05 8.4587e-02 1.9708e-02 1.9045e-01 8.8008e-02 9.2169e-01 8.3507e-02 1.0067e+00 8.1584e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 352: 1.0251e+02 -4.0998e+00 -2.3201e+00 -4.0405e+00 -1.0091e+00 -4.2159e-02 4.1973e-03 1.9819e-05 8.4804e-02 1.9678e-02 1.9040e-01 8.7894e-02 9.2113e-01 8.3528e-02 1.0061e+00 8.1554e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 353: 1.0251e+02 -4.0998e+00 -2.3202e+00 -4.0405e+00 -1.0088e+00 -4.2123e-02 4.1968e-03 1.9855e-05 8.4945e-02 1.9634e-02 1.9049e-01 8.7941e-02 9.2108e-01 8.3500e-02 1.0058e+00 8.1548e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 354: 1.0251e+02 -4.0998e+00 -2.3204e+00 -4.0404e+00 -1.0087e+00 -4.2217e-02 4.1918e-03 1.9909e-05 8.5122e-02 1.9565e-02 1.9055e-01 8.7948e-02 9.2088e-01 8.3523e-02 1.0059e+00 8.1530e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 355: 1.0251e+02 -4.0998e+00 -2.3206e+00 -4.0404e+00 -1.0086e+00 -4.2057e-02 4.1853e-03 1.9973e-05 8.5389e-02 1.9505e-02 1.9057e-01 8.8109e-02 9.2100e-01 8.3496e-02 1.0058e+00 8.1520e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 356: 1.0251e+02 -4.0998e+00 -2.3209e+00 -4.0403e+00 -1.0084e+00 -4.1880e-02 4.1796e-03 2.0058e-05 8.5446e-02 1.9451e-02 1.9063e-01 8.7944e-02 9.2086e-01 8.3483e-02 1.0061e+00 8.1488e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 357: 1.0251e+02 -4.0998e+00 -2.3210e+00 -4.0404e+00 -1.0084e+00 -4.1565e-02 4.1858e-03 2.0131e-05 8.5481e-02 1.9391e-02 1.9072e-01 8.7879e-02 9.2119e-01 8.3465e-02 1.0066e+00 8.1468e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 358: 1.0251e+02 -4.0998e+00 -2.3213e+00 -4.0404e+00 -1.0084e+00 -4.1497e-02 4.1826e-03 2.0168e-05 8.5661e-02 1.9361e-02 1.9086e-01 8.7635e-02 9.2095e-01 8.3475e-02 1.0069e+00 8.1445e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 359: 1.0251e+02 -4.0997e+00 -2.3212e+00 -4.0405e+00 -1.0083e+00 -4.1127e-02 4.1993e-03 2.0188e-05 8.5904e-02 1.9347e-02 1.9078e-01 8.7558e-02 9.2087e-01 8.3451e-02 1.0068e+00 8.1461e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 360: 1.0251e+02 -4.0997e+00 -2.3215e+00 -4.0405e+00 -1.0082e+00 -4.0919e-02 4.2006e-03 2.0173e-05 8.6133e-02 1.9333e-02 1.9071e-01 8.7479e-02 9.2061e-01 8.3439e-02 1.0067e+00 8.1453e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 361: 1.0251e+02 -4.0997e+00 -2.3218e+00 -4.0406e+00 -1.0084e+00 -4.0317e-02 4.2013e-03 2.0253e-05 8.6558e-02 1.9351e-02 1.9075e-01 8.7309e-02 9.2060e-01 8.3425e-02 1.0069e+00 8.1464e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 362: 1.0251e+02 -4.0997e+00 -2.3221e+00 -4.0407e+00 -1.0086e+00 -3.9991e-02 4.2004e-03 2.0305e-05 8.6952e-02 1.9369e-02 1.9077e-01 8.7106e-02 9.2037e-01 8.3462e-02 1.0072e+00 8.1464e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 363: 1.0251e+02 -4.0997e+00 -2.3224e+00 -4.0407e+00 -1.0086e+00 -3.9745e-02 4.1920e-03 2.0350e-05 8.7210e-02 1.9373e-02 1.9095e-01 8.6967e-02 9.2025e-01 8.3462e-02 1.0070e+00 8.1489e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 364: 1.0251e+02 -4.0997e+00 -2.3225e+00 -4.0407e+00 -1.0088e+00 -3.9585e-02 4.1826e-03 2.0355e-05 8.7449e-02 1.9353e-02 1.9099e-01 8.7119e-02 9.2081e-01 8.3468e-02 1.0070e+00 8.1514e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 365: 1.0251e+02 -4.0997e+00 -2.3224e+00 -4.0407e+00 -1.0088e+00 -3.9531e-02 4.1781e-03 2.0298e-05 8.7646e-02 1.9346e-02 1.9083e-01 8.6997e-02 9.2106e-01 8.3455e-02 1.0068e+00 8.1546e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 366: 1.0251e+02 -4.0997e+00 -2.3223e+00 -4.0407e+00 -1.0088e+00 -3.9436e-02 4.1805e-03 2.0301e-05 8.7772e-02 1.9354e-02 1.9074e-01 8.7057e-02 9.2118e-01 8.3426e-02 1.0064e+00 8.1555e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 367: 1.0251e+02 -4.0997e+00 -2.3223e+00 -4.0408e+00 -1.0088e+00 -3.9172e-02 4.1791e-03 2.0368e-05 8.7914e-02 1.9333e-02 1.9063e-01 8.6948e-02 9.2106e-01 8.3409e-02 1.0060e+00 8.1558e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 368: 1.0251e+02 -4.0997e+00 -2.3222e+00 -4.0410e+00 -1.0088e+00 -3.8640e-02 4.1857e-03 2.0343e-05 8.7937e-02 1.9334e-02 1.9051e-01 8.6857e-02 9.2143e-01 8.3379e-02 1.0058e+00 8.1564e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 369: 1.0251e+02 -4.0997e+00 -2.3223e+00 -4.0411e+00 -1.0088e+00 -3.8331e-02 4.1862e-03 2.0309e-05 8.7933e-02 1.9319e-02 1.9046e-01 8.6689e-02 9.2126e-01 8.3410e-02 1.0053e+00 8.1559e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 370: 1.0251e+02 -4.0997e+00 -2.3222e+00 -4.0413e+00 -1.0088e+00 -3.7984e-02 4.1921e-03 2.0301e-05 8.8082e-02 1.9313e-02 1.9050e-01 8.6622e-02 9.2101e-01 8.3424e-02 1.0049e+00 8.1559e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 371: 1.0251e+02 -4.0998e+00 -2.3222e+00 -4.0415e+00 -1.0087e+00 -3.7729e-02 4.1972e-03 2.0277e-05 8.8271e-02 1.9308e-02 1.9035e-01 8.6655e-02 9.2092e-01 8.3426e-02 1.0046e+00 8.1575e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 372: 1.0251e+02 -4.0998e+00 -2.3222e+00 -4.0414e+00 -1.0087e+00 -3.7571e-02 4.1922e-03 2.0292e-05 8.8651e-02 1.9317e-02 1.9025e-01 8.6528e-02 9.2126e-01 8.3440e-02 1.0046e+00 8.1576e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 373: 1.0251e+02 -4.0998e+00 -2.3223e+00 -4.0415e+00 -1.0087e+00 -3.7327e-02 4.1971e-03 2.0343e-05 8.8865e-02 1.9290e-02 1.9002e-01 8.6437e-02 9.2122e-01 8.3475e-02 1.0044e+00 8.1571e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 374: 1.0251e+02 -4.0998e+00 -2.3224e+00 -4.0415e+00 -1.0089e+00 -3.7275e-02 4.2072e-03 2.0450e-05 8.9078e-02 1.9306e-02 1.9002e-01 8.6224e-02 9.2111e-01 8.3480e-02 1.0047e+00 8.1569e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 375: 1.0251e+02 -4.0998e+00 -2.3226e+00 -4.0415e+00 -1.0089e+00 -3.7080e-02 4.2062e-03 2.0489e-05 8.9178e-02 1.9320e-02 1.9016e-01 8.6141e-02 9.2116e-01 8.3483e-02 1.0047e+00 8.1586e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 376: 1.0251e+02 -4.0998e+00 -2.3230e+00 -4.0415e+00 -1.0089e+00 -3.7043e-02 4.2105e-03 2.0517e-05 8.9291e-02 1.9325e-02 1.9018e-01 8.6033e-02 9.2114e-01 8.3474e-02 1.0046e+00 8.1572e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 377: 1.0251e+02 -4.0998e+00 -2.3234e+00 -4.0414e+00 -1.0090e+00 -3.7302e-02 4.2097e-03 2.0524e-05 8.9438e-02 1.9333e-02 1.9012e-01 8.6018e-02 9.2123e-01 8.3476e-02 1.0046e+00 8.1545e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 378: 1.0251e+02 -4.0998e+00 -2.3234e+00 -4.0413e+00 -1.0089e+00 -3.7617e-02 4.2161e-03 2.0520e-05 8.9567e-02 1.9305e-02 1.9012e-01 8.6106e-02 9.2115e-01 8.3444e-02 1.0049e+00 8.1534e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 379: 1.0251e+02 -4.0998e+00 -2.3232e+00 -4.0412e+00 -1.0088e+00 -3.8039e-02 4.2231e-03 2.0484e-05 8.9704e-02 1.9276e-02 1.9015e-01 8.5914e-02 9.2060e-01 8.3438e-02 1.0048e+00 8.1532e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 380: 1.0251e+02 -4.0998e+00 -2.3229e+00 -4.0409e+00 -1.0088e+00 -3.8613e-02 4.2221e-03 2.0452e-05 8.9751e-02 1.9293e-02 1.9018e-01 8.5907e-02 9.2032e-01 8.3428e-02 1.0045e+00 8.1545e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 381: 1.0251e+02 -4.0998e+00 -2.3228e+00 -4.0408e+00 -1.0088e+00 -3.8992e-02 4.2177e-03 2.0475e-05 8.9641e-02 1.9314e-02 1.9014e-01 8.5978e-02 9.2015e-01 8.3429e-02 1.0040e+00 8.1535e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 382: 1.0251e+02 -4.0998e+00 -2.3228e+00 -4.0408e+00 -1.0088e+00 -3.9393e-02 4.2092e-03 2.0508e-05 8.9624e-02 1.9352e-02 1.9010e-01 8.5929e-02 9.2037e-01 8.3422e-02 1.0037e+00 8.1535e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 383: 1.0251e+02 -4.0998e+00 -2.3226e+00 -4.0407e+00 -1.0089e+00 -3.9650e-02 4.2080e-03 2.0503e-05 8.9621e-02 1.9349e-02 1.9000e-01 8.5735e-02 9.2021e-01 8.3436e-02 1.0038e+00 8.1544e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 384: 1.0251e+02 -4.0998e+00 -2.3223e+00 -4.0407e+00 -1.0089e+00 -3.9709e-02 4.2111e-03 2.0489e-05 8.9690e-02 1.9347e-02 1.8985e-01 8.5516e-02 9.2025e-01 8.3420e-02 1.0037e+00 8.1541e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 385: 1.0251e+02 -4.0998e+00 -2.3225e+00 -4.0406e+00 -1.0087e+00 -3.9762e-02 4.2130e-03 2.0458e-05 8.9795e-02 1.9380e-02 1.8978e-01 8.5306e-02 9.2055e-01 8.3405e-02 1.0034e+00 8.1518e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 386: 1.0251e+02 -4.0998e+00 -2.3226e+00 -4.0407e+00 -1.0087e+00 -3.9801e-02 4.2117e-03 2.0473e-05 8.9838e-02 1.9386e-02 1.8986e-01 8.5045e-02 9.2034e-01 8.3388e-02 1.0036e+00 8.1512e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 387: 1.0251e+02 -4.0998e+00 -2.3228e+00 -4.0408e+00 -1.0088e+00 -3.9548e-02 4.2221e-03 2.0474e-05 8.9914e-02 1.9399e-02 1.9001e-01 8.4840e-02 9.2080e-01 8.3373e-02 1.0037e+00 8.1503e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 388: 1.0251e+02 -4.0998e+00 -2.3230e+00 -4.0408e+00 -1.0088e+00 -3.9408e-02 4.2272e-03 2.0464e-05 8.9977e-02 1.9383e-02 1.9000e-01 8.4644e-02 9.2070e-01 8.3377e-02 1.0034e+00 8.1494e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 389: 1.0250e+02 -4.0998e+00 -2.3229e+00 -4.0408e+00 -1.0087e+00 -3.9326e-02 4.2285e-03 2.0459e-05 8.9927e-02 1.9366e-02 1.9001e-01 8.4485e-02 9.2063e-01 8.3367e-02 1.0032e+00 8.1487e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 390: 1.0250e+02 -4.0998e+00 -2.3231e+00 -4.0409e+00 -1.0086e+00 -3.9130e-02 4.2286e-03 2.0423e-05 8.9894e-02 1.9331e-02 1.8996e-01 8.4434e-02 9.2054e-01 8.3339e-02 1.0032e+00 8.1481e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 391: 1.0250e+02 -4.0998e+00 -2.3232e+00 -4.0410e+00 -1.0086e+00 -3.8976e-02 4.2242e-03 2.0419e-05 8.9782e-02 1.9299e-02 1.8992e-01 8.4344e-02 9.2089e-01 8.3320e-02 1.0032e+00 8.1480e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 392: 1.0250e+02 -4.0998e+00 -2.3232e+00 -4.0409e+00 -1.0086e+00 -3.8856e-02 4.2179e-03 2.0396e-05 8.9773e-02 1.9263e-02 1.8984e-01 8.4469e-02 9.2084e-01 8.3309e-02 1.0034e+00 8.1489e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 393: 1.0250e+02 -4.0998e+00 -2.3234e+00 -4.0409e+00 -1.0089e+00 -3.8820e-02 4.2135e-03 2.0375e-05 8.9746e-02 1.9259e-02 1.8972e-01 8.4731e-02 9.2088e-01 8.3310e-02 1.0031e+00 8.1481e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 394: 1.0250e+02 -4.0998e+00 -2.3234e+00 -4.0410e+00 -1.0089e+00 -3.8759e-02 4.2123e-03 2.0382e-05 8.9791e-02 1.9271e-02 1.8958e-01 8.5075e-02 9.2064e-01 8.3316e-02 1.0028e+00 8.1483e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 395: 1.0250e+02 -4.0998e+00 -2.3234e+00 -4.0410e+00 -1.0090e+00 -3.8565e-02 4.2179e-03 2.0420e-05 8.9844e-02 1.9279e-02 1.8948e-01 8.5286e-02 9.2070e-01 8.3311e-02 1.0027e+00 8.1499e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 396: 1.0250e+02 -4.0998e+00 -2.3233e+00 -4.0411e+00 -1.0092e+00 -3.8505e-02 4.2207e-03 2.0445e-05 8.9863e-02 1.9281e-02 1.8944e-01 8.5452e-02 9.2053e-01 8.3326e-02 1.0028e+00 8.1524e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 397: 1.0250e+02 -4.0998e+00 -2.3232e+00 -4.0411e+00 -1.0093e+00 -3.8366e-02 4.2115e-03 2.0410e-05 8.9792e-02 1.9287e-02 1.8938e-01 8.5649e-02 9.2063e-01 8.3351e-02 1.0034e+00 8.1519e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 398: 1.0250e+02 -4.0998e+00 -2.3234e+00 -4.0411e+00 -1.0093e+00 -3.8179e-02 4.2049e-03 2.0362e-05 8.9718e-02 1.9281e-02 1.8943e-01 8.5813e-02 9.2065e-01 8.3391e-02 1.0040e+00 8.1513e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 399: 1.0250e+02 -4.0998e+00 -2.3236e+00 -4.0411e+00 -1.0093e+00 -3.8020e-02 4.2015e-03 2.0320e-05 8.9743e-02 1.9283e-02 1.8934e-01 8.5899e-02 9.2056e-01 8.3426e-02 1.0045e+00 8.1500e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 400: 1.0250e+02 -4.0998e+00 -2.3237e+00 -4.0412e+00 -1.0093e+00 -3.7796e-02 4.2017e-03 2.0296e-05 8.9684e-02 1.9297e-02 1.8932e-01 8.5849e-02 9.2107e-01 8.3413e-02 1.0051e+00 8.1502e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 401: 1.0250e+02 -4.0998e+00 -2.3238e+00 -4.0413e+00 -1.0093e+00 -3.7697e-02 4.1959e-03 2.0275e-05 8.9618e-02 1.9291e-02 1.8914e-01 8.5796e-02 9.2086e-01 8.3480e-02 1.0051e+00 8.1510e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 402: 1.0250e+02 -4.0998e+00 -2.3238e+00 -4.0414e+00 -1.0093e+00 -3.7639e-02 4.1863e-03 2.0273e-05 8.9522e-02 1.9285e-02 1.8898e-01 8.5723e-02 9.2041e-01 8.3534e-02 1.0053e+00 8.1520e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 403: 1.0250e+02 -4.0998e+00 -2.3238e+00 -4.0415e+00 -1.0093e+00 -3.7634e-02 4.1878e-03 2.0250e-05 8.9456e-02 1.9288e-02 1.8895e-01 8.5791e-02 9.1990e-01 8.3549e-02 1.0055e+00 8.1545e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 404: 1.0250e+02 -4.0999e+00 -2.3239e+00 -4.0416e+00 -1.0094e+00 -3.7581e-02 4.1854e-03 2.0292e-05 8.9326e-02 1.9326e-02 1.8902e-01 8.5928e-02 9.2016e-01 8.3542e-02 1.0053e+00 8.1565e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 405: 1.0250e+02 -4.0999e+00 -2.3239e+00 -4.0415e+00 -1.0094e+00 -3.7740e-02 4.1804e-03 2.0333e-05 8.9304e-02 1.9334e-02 1.8892e-01 8.6225e-02 9.1978e-01 8.3559e-02 1.0052e+00 8.1588e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 406: 1.0250e+02 -4.0999e+00 -2.3241e+00 -4.0415e+00 -1.0093e+00 -3.7837e-02 4.1866e-03 2.0375e-05 8.9281e-02 1.9322e-02 1.8906e-01 8.6421e-02 9.1972e-01 8.3556e-02 1.0051e+00 8.1596e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 407: 1.0250e+02 -4.0999e+00 -2.3240e+00 -4.0415e+00 -1.0092e+00 -3.8211e-02 4.1948e-03 2.0335e-05 8.9117e-02 1.9303e-02 1.8913e-01 8.6644e-02 9.1975e-01 8.3592e-02 1.0052e+00 8.1594e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 408: 1.0250e+02 -4.0999e+00 -2.3239e+00 -4.0415e+00 -1.0091e+00 -3.8144e-02 4.2081e-03 2.0320e-05 8.9057e-02 1.9287e-02 1.8912e-01 8.6825e-02 9.1992e-01 8.3572e-02 1.0054e+00 8.1577e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 409: 1.0250e+02 -4.0999e+00 -2.3239e+00 -4.0415e+00 -1.0092e+00 -3.8261e-02 4.2186e-03 2.0295e-05 8.9007e-02 1.9339e-02 1.8923e-01 8.6869e-02 9.1991e-01 8.3568e-02 1.0053e+00 8.1578e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 410: 1.0250e+02 -4.0999e+00 -2.3239e+00 -4.0414e+00 -1.0093e+00 -3.8478e-02 4.2150e-03 2.0311e-05 8.9089e-02 1.9427e-02 1.8939e-01 8.7036e-02 9.2050e-01 8.3537e-02 1.0051e+00 8.1581e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 411: 1.0250e+02 -4.0999e+00 -2.3238e+00 -4.0413e+00 -1.0092e+00 -3.8732e-02 4.2116e-03 2.0289e-05 8.9015e-02 1.9467e-02 1.8939e-01 8.7005e-02 9.2025e-01 8.3538e-02 1.0049e+00 8.1581e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 412: 1.0250e+02 -4.0999e+00 -2.3238e+00 -4.0413e+00 -1.0092e+00 -3.8793e-02 4.2085e-03 2.0295e-05 8.9020e-02 1.9477e-02 1.8946e-01 8.7080e-02 9.2047e-01 8.3532e-02 1.0049e+00 8.1575e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 413: 1.0250e+02 -4.0999e+00 -2.3236e+00 -4.0412e+00 -1.0093e+00 -3.8937e-02 4.2069e-03 2.0288e-05 8.9121e-02 1.9495e-02 1.8939e-01 8.7203e-02 9.2043e-01 8.3528e-02 1.0046e+00 8.1581e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 414: 1.0250e+02 -4.0999e+00 -2.3233e+00 -4.0412e+00 -1.0093e+00 -3.9068e-02 4.2065e-03 2.0272e-05 8.9126e-02 1.9508e-02 1.8939e-01 8.7485e-02 9.2038e-01 8.3517e-02 1.0046e+00 8.1589e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 415: 1.0250e+02 -4.0999e+00 -2.3234e+00 -4.0412e+00 -1.0092e+00 -3.9299e-02 4.2117e-03 2.0277e-05 8.8971e-02 1.9564e-02 1.8955e-01 8.7734e-02 9.2051e-01 8.3502e-02 1.0048e+00 8.1575e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 416: 1.0250e+02 -4.0999e+00 -2.3232e+00 -4.0413e+00 -1.0092e+00 -3.9575e-02 4.2122e-03 2.0269e-05 8.8909e-02 1.9609e-02 1.8954e-01 8.7910e-02 9.2061e-01 8.3488e-02 1.0045e+00 8.1561e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 417: 1.0250e+02 -4.0999e+00 -2.3228e+00 -4.0412e+00 -1.0092e+00 -3.9794e-02 4.2133e-03 2.0289e-05 8.8845e-02 1.9606e-02 1.8949e-01 8.8036e-02 9.2065e-01 8.3481e-02 1.0047e+00 8.1558e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 418: 1.0250e+02 -4.0999e+00 -2.3226e+00 -4.0412e+00 -1.0092e+00 -4.0019e-02 4.2209e-03 2.0279e-05 8.8864e-02 1.9618e-02 1.8939e-01 8.8094e-02 9.2062e-01 8.3490e-02 1.0044e+00 8.1566e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 419: 1.0250e+02 -4.0999e+00 -2.3225e+00 -4.0411e+00 -1.0092e+00 -4.0090e-02 4.2242e-03 2.0258e-05 8.9089e-02 1.9644e-02 1.8924e-01 8.8285e-02 9.2082e-01 8.3484e-02 1.0040e+00 8.1567e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 420: 1.0250e+02 -4.0999e+00 -2.3223e+00 -4.0410e+00 -1.0091e+00 -4.0260e-02 4.2298e-03 2.0249e-05 8.9215e-02 1.9640e-02 1.8919e-01 8.8683e-02 9.2127e-01 8.3454e-02 1.0041e+00 8.1564e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 421: 1.0250e+02 -4.0998e+00 -2.3222e+00 -4.0410e+00 -1.0090e+00 -4.0359e-02 4.2292e-03 2.0289e-05 8.9366e-02 1.9642e-02 1.8928e-01 8.8905e-02 9.2154e-01 8.3452e-02 1.0038e+00 8.1572e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 422: 1.0250e+02 -4.0998e+00 -2.3223e+00 -4.0410e+00 -1.0088e+00 -4.0380e-02 4.2311e-03 2.0289e-05 8.9318e-02 1.9636e-02 1.8934e-01 8.9025e-02 9.2137e-01 8.3486e-02 1.0039e+00 8.1562e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 423: 1.0250e+02 -4.0998e+00 -2.3224e+00 -4.0411e+00 -1.0088e+00 -4.0256e-02 4.2283e-03 2.0277e-05 8.9324e-02 1.9645e-02 1.8923e-01 8.9305e-02 9.2129e-01 8.3484e-02 1.0038e+00 8.1565e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 424: 1.0250e+02 -4.0998e+00 -2.3226e+00 -4.0412e+00 -1.0088e+00 -4.0075e-02 4.2333e-03 2.0245e-05 8.9193e-02 1.9657e-02 1.8914e-01 8.9480e-02 9.2122e-01 8.3487e-02 1.0039e+00 8.1587e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 425: 1.0250e+02 -4.0998e+00 -2.3226e+00 -4.0413e+00 -1.0088e+00 -3.9950e-02 4.2360e-03 2.0257e-05 8.9170e-02 1.9644e-02 1.8924e-01 8.9622e-02 9.2104e-01 8.3492e-02 1.0042e+00 8.1599e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 426: 1.0250e+02 -4.0998e+00 -2.3226e+00 -4.0413e+00 -1.0088e+00 -3.9789e-02 4.2376e-03 2.0245e-05 8.9143e-02 1.9654e-02 1.8917e-01 8.9791e-02 9.2100e-01 8.3514e-02 1.0039e+00 8.1607e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 427: 1.0250e+02 -4.0998e+00 -2.3224e+00 -4.0414e+00 -1.0087e+00 -3.9766e-02 4.2469e-03 2.0228e-05 8.9102e-02 1.9656e-02 1.8913e-01 9.0076e-02 9.2110e-01 8.3499e-02 1.0037e+00 8.1607e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 428: 1.0250e+02 -4.0998e+00 -2.3225e+00 -4.0414e+00 -1.0088e+00 -3.9662e-02 4.2522e-03 2.0205e-05 8.9151e-02 1.9669e-02 1.8912e-01 9.0312e-02 9.2102e-01 8.3483e-02 1.0036e+00 8.1599e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 429: 1.0250e+02 -4.0998e+00 -2.3225e+00 -4.0414e+00 -1.0089e+00 -3.9547e-02 4.2615e-03 2.0187e-05 8.9103e-02 1.9681e-02 1.8907e-01 9.0576e-02 9.2082e-01 8.3488e-02 1.0035e+00 8.1592e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 430: 1.0250e+02 -4.0998e+00 -2.3224e+00 -4.0414e+00 -1.0088e+00 -3.9593e-02 4.2613e-03 2.0159e-05 8.9075e-02 1.9692e-02 1.8894e-01 9.0762e-02 9.2073e-01 8.3487e-02 1.0035e+00 8.1603e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 431: 1.0250e+02 -4.0998e+00 -2.3223e+00 -4.0413e+00 -1.0088e+00 -3.9929e-02 4.2668e-03 2.0112e-05 8.8982e-02 1.9682e-02 1.8901e-01 9.0997e-02 9.2043e-01 8.3487e-02 1.0036e+00 8.1604e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 432: 1.0250e+02 -4.0998e+00 -2.3223e+00 -4.0413e+00 -1.0088e+00 -4.0182e-02 4.2693e-03 2.0089e-05 8.8860e-02 1.9659e-02 1.8898e-01 9.1110e-02 9.2024e-01 8.3490e-02 1.0036e+00 8.1585e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 433: 1.0250e+02 -4.0998e+00 -2.3222e+00 -4.0412e+00 -1.0088e+00 -4.0415e-02 4.2706e-03 2.0081e-05 8.8670e-02 1.9650e-02 1.8899e-01 9.1199e-02 9.1999e-01 8.3485e-02 1.0036e+00 8.1587e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 434: 1.0250e+02 -4.0998e+00 -2.3220e+00 -4.0412e+00 -1.0087e+00 -4.0405e-02 4.2661e-03 2.0060e-05 8.8576e-02 1.9667e-02 1.8897e-01 9.1180e-02 9.1998e-01 8.3468e-02 1.0034e+00 8.1594e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 435: 1.0250e+02 -4.0998e+00 -2.3218e+00 -4.0413e+00 -1.0087e+00 -4.0471e-02 4.2639e-03 2.0050e-05 8.8450e-02 1.9671e-02 1.8891e-01 9.1156e-02 9.1970e-01 8.3469e-02 1.0033e+00 8.1602e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 436: 1.0250e+02 -4.0998e+00 -2.3216e+00 -4.0413e+00 -1.0086e+00 -4.0478e-02 4.2614e-03 2.0025e-05 8.8470e-02 1.9677e-02 1.8892e-01 9.1234e-02 9.1948e-01 8.3484e-02 1.0033e+00 8.1608e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 437: 1.0250e+02 -4.0998e+00 -2.3214e+00 -4.0413e+00 -1.0086e+00 -4.0648e-02 4.2569e-03 2.0021e-05 8.8378e-02 1.9694e-02 1.8896e-01 9.1289e-02 9.1946e-01 8.3486e-02 1.0034e+00 8.1608e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 438: 1.0250e+02 -4.0998e+00 -2.3214e+00 -4.0413e+00 -1.0085e+00 -4.0807e-02 4.2559e-03 2.0029e-05 8.8244e-02 1.9704e-02 1.8898e-01 9.1352e-02 9.1920e-01 8.3494e-02 1.0034e+00 8.1604e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 439: 1.0250e+02 -4.0998e+00 -2.3215e+00 -4.0413e+00 -1.0084e+00 -4.0814e-02 4.2472e-03 2.0035e-05 8.8064e-02 1.9736e-02 1.8905e-01 9.1469e-02 9.1900e-01 8.3510e-02 1.0032e+00 8.1602e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 440: 1.0250e+02 -4.0998e+00 -2.3216e+00 -4.0414e+00 -1.0084e+00 -4.0845e-02 4.2385e-03 2.0044e-05 8.7953e-02 1.9775e-02 1.8906e-01 9.1482e-02 9.1902e-01 8.3529e-02 1.0029e+00 8.1605e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 441: 1.0250e+02 -4.0998e+00 -2.3218e+00 -4.0415e+00 -1.0084e+00 -4.0561e-02 4.2293e-03 2.0096e-05 8.7978e-02 1.9848e-02 1.8914e-01 9.1431e-02 9.1890e-01 8.3545e-02 1.0026e+00 8.1618e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 442: 1.0250e+02 -4.0998e+00 -2.3219e+00 -4.0415e+00 -1.0085e+00 -4.0297e-02 4.2190e-03 2.0140e-05 8.8016e-02 1.9884e-02 1.8912e-01 9.1373e-02 9.1910e-01 8.3556e-02 1.0025e+00 8.1632e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 443: 1.0250e+02 -4.0998e+00 -2.3222e+00 -4.0415e+00 -1.0086e+00 -4.0124e-02 4.2172e-03 2.0182e-05 8.8183e-02 1.9921e-02 1.8920e-01 9.1354e-02 9.1928e-01 8.3555e-02 1.0023e+00 8.1646e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 444: 1.0250e+02 -4.0999e+00 -2.3223e+00 -4.0416e+00 -1.0084e+00 -4.0120e-02 4.2226e-03 2.0208e-05 8.8142e-02 1.9980e-02 1.8916e-01 9.1269e-02 9.1934e-01 8.3540e-02 1.0020e+00 8.1653e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 445: 1.0250e+02 -4.0999e+00 -2.3223e+00 -4.0416e+00 -1.0083e+00 -4.0180e-02 4.2279e-03 2.0283e-05 8.8188e-02 2.0009e-02 1.8925e-01 9.1096e-02 9.1924e-01 8.3538e-02 1.0017e+00 8.1644e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 446: 1.0250e+02 -4.0999e+00 -2.3223e+00 -4.0417e+00 -1.0084e+00 -4.0083e-02 4.2373e-03 2.0357e-05 8.8255e-02 2.0030e-02 1.8937e-01 9.0921e-02 9.1921e-01 8.3535e-02 1.0015e+00 8.1652e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 447: 1.0250e+02 -4.0999e+00 -2.3223e+00 -4.0417e+00 -1.0083e+00 -4.0032e-02 4.2591e-03 2.0418e-05 8.8322e-02 2.0055e-02 1.8931e-01 9.0741e-02 9.1928e-01 8.3527e-02 1.0011e+00 8.1662e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 448: 1.0250e+02 -4.0999e+00 -2.3224e+00 -4.0417e+00 -1.0083e+00 -4.0042e-02 4.2759e-03 2.0499e-05 8.8372e-02 2.0083e-02 1.8935e-01 9.0554e-02 9.1942e-01 8.3524e-02 1.0010e+00 8.1661e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 449: 1.0250e+02 -4.0999e+00 -2.3224e+00 -4.0417e+00 -1.0083e+00 -4.0219e-02 4.2779e-03 2.0525e-05 8.8377e-02 2.0104e-02 1.8937e-01 9.0424e-02 9.1970e-01 8.3510e-02 1.0009e+00 8.1654e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 450: 1.0250e+02 -4.0999e+00 -2.3223e+00 -4.0416e+00 -1.0084e+00 -4.0390e-02 4.2779e-03 2.0520e-05 8.8387e-02 2.0120e-02 1.8939e-01 9.0277e-02 9.1991e-01 8.3489e-02 1.0010e+00 8.1662e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 451: 1.0250e+02 -4.0999e+00 -2.3221e+00 -4.0415e+00 -1.0085e+00 -4.0403e-02 4.2785e-03 2.0554e-05 8.8442e-02 2.0130e-02 1.8934e-01 9.0032e-02 9.2001e-01 8.3485e-02 1.0011e+00 8.1676e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 452: 1.0250e+02 -4.0999e+00 -2.3220e+00 -4.0415e+00 -1.0084e+00 -4.0503e-02 4.2730e-03 2.0537e-05 8.8507e-02 2.0135e-02 1.8926e-01 8.9777e-02 9.2031e-01 8.3473e-02 1.0013e+00 8.1671e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 453: 1.0250e+02 -4.0999e+00 -2.3221e+00 -4.0415e+00 -1.0084e+00 -4.0716e-02 4.2650e-03 2.0525e-05 8.8565e-02 2.0168e-02 1.8921e-01 8.9653e-02 9.2030e-01 8.3473e-02 1.0010e+00 8.1665e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 454: 1.0250e+02 -4.0999e+00 -2.3221e+00 -4.0415e+00 -1.0083e+00 -4.0900e-02 4.2583e-03 2.0505e-05 8.8572e-02 2.0194e-02 1.8912e-01 8.9524e-02 9.2039e-01 8.3457e-02 1.0009e+00 8.1658e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 455: 1.0250e+02 -4.0999e+00 -2.3220e+00 -4.0415e+00 -1.0083e+00 -4.0930e-02 4.2524e-03 2.0495e-05 8.8643e-02 2.0246e-02 1.8914e-01 8.9416e-02 9.2035e-01 8.3454e-02 1.0006e+00 8.1655e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 456: 1.0250e+02 -4.0999e+00 -2.3218e+00 -4.0414e+00 -1.0084e+00 -4.1008e-02 4.2455e-03 2.0482e-05 8.8831e-02 2.0290e-02 1.8904e-01 8.9438e-02 9.2042e-01 8.3448e-02 1.0005e+00 8.1672e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 457: 1.0250e+02 -4.0999e+00 -2.3216e+00 -4.0414e+00 -1.0085e+00 -4.1073e-02 4.2376e-03 2.0479e-05 8.8831e-02 2.0310e-02 1.8893e-01 8.9411e-02 9.2049e-01 8.3438e-02 1.0005e+00 8.1677e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 458: 1.0250e+02 -4.0999e+00 -2.3215e+00 -4.0414e+00 -1.0085e+00 -4.1036e-02 4.2288e-03 2.0479e-05 8.8894e-02 2.0311e-02 1.8879e-01 8.9378e-02 9.2055e-01 8.3419e-02 1.0006e+00 8.1689e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 459: 1.0250e+02 -4.0999e+00 -2.3216e+00 -4.0414e+00 -1.0085e+00 -4.1084e-02 4.2296e-03 2.0472e-05 8.8976e-02 2.0290e-02 1.8876e-01 8.9365e-02 9.2056e-01 8.3404e-02 1.0007e+00 8.1678e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 460: 1.0250e+02 -4.0999e+00 -2.3215e+00 -4.0414e+00 -1.0084e+00 -4.1065e-02 4.2257e-03 2.0473e-05 8.8978e-02 2.0254e-02 1.8871e-01 8.9287e-02 9.2061e-01 8.3386e-02 1.0007e+00 8.1663e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 461: 1.0250e+02 -4.0999e+00 -2.3213e+00 -4.0414e+00 -1.0084e+00 -4.1142e-02 4.2254e-03 2.0441e-05 8.8952e-02 2.0238e-02 1.8864e-01 8.9236e-02 9.2067e-01 8.3359e-02 1.0007e+00 8.1670e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 462: 1.0250e+02 -4.0999e+00 -2.3213e+00 -4.0413e+00 -1.0083e+00 -4.1199e-02 4.2230e-03 2.0409e-05 8.9161e-02 2.0235e-02 1.8852e-01 8.9179e-02 9.2070e-01 8.3339e-02 1.0005e+00 8.1686e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 463: 1.0250e+02 -4.0999e+00 -2.3214e+00 -4.0413e+00 -1.0084e+00 -4.1131e-02 4.2191e-03 2.0397e-05 8.9356e-02 2.0251e-02 1.8850e-01 8.9138e-02 9.2098e-01 8.3308e-02 1.0003e+00 8.1688e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 464: 1.0250e+02 -4.0999e+00 -2.3213e+00 -4.0414e+00 -1.0084e+00 -4.0937e-02 4.2187e-03 2.0395e-05 8.9553e-02 2.0237e-02 1.8848e-01 8.9097e-02 9.2108e-01 8.3293e-02 1.0001e+00 8.1684e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 465: 1.0250e+02 -4.0999e+00 -2.3213e+00 -4.0414e+00 -1.0086e+00 -4.0873e-02 4.2226e-03 2.0374e-05 8.9675e-02 2.0210e-02 1.8854e-01 8.9045e-02 9.2115e-01 8.3282e-02 1.0002e+00 8.1678e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 466: 1.0250e+02 -4.0999e+00 -2.3213e+00 -4.0414e+00 -1.0085e+00 -4.1046e-02 4.2312e-03 2.0379e-05 8.9703e-02 2.0232e-02 1.8852e-01 8.9031e-02 9.2100e-01 8.3294e-02 9.9982e-01 8.1665e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 467: 1.0250e+02 -4.0999e+00 -2.3214e+00 -4.0414e+00 -1.0086e+00 -4.1081e-02 4.2382e-03 2.0421e-05 8.9802e-02 2.0266e-02 1.8851e-01 8.9175e-02 9.2124e-01 8.3271e-02 9.9943e-01 8.1671e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 468: 1.0250e+02 -4.0999e+00 -2.3215e+00 -4.0414e+00 -1.0085e+00 -4.1107e-02 4.2412e-03 2.0446e-05 8.9937e-02 2.0281e-02 1.8857e-01 8.9238e-02 9.2125e-01 8.3255e-02 9.9912e-01 8.1659e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 469: 1.0250e+02 -4.0999e+00 -2.3214e+00 -4.0414e+00 -1.0084e+00 -4.1269e-02 4.2380e-03 2.0449e-05 8.9938e-02 2.0285e-02 1.8867e-01 8.9378e-02 9.2144e-01 8.3225e-02 9.9906e-01 8.1651e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 470: 1.0250e+02 -4.0999e+00 -2.3212e+00 -4.0413e+00 -1.0083e+00 -4.1552e-02 4.2384e-03 2.0437e-05 8.9924e-02 2.0280e-02 1.8878e-01 8.9520e-02 9.2149e-01 8.3205e-02 9.9880e-01 8.1648e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 471: 1.0250e+02 -4.0999e+00 -2.3210e+00 -4.0412e+00 -1.0082e+00 -4.2096e-02 4.2375e-03 2.0433e-05 8.9875e-02 2.0267e-02 1.8880e-01 8.9608e-02 9.2149e-01 8.3221e-02 9.9869e-01 8.1642e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 472: 1.0250e+02 -4.0999e+00 -2.3210e+00 -4.0411e+00 -1.0081e+00 -4.2380e-02 4.2446e-03 2.0435e-05 8.9823e-02 2.0262e-02 1.8885e-01 8.9602e-02 9.2156e-01 8.3233e-02 9.9868e-01 8.1643e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 473: 1.0250e+02 -4.0999e+00 -2.3210e+00 -4.0410e+00 -1.0080e+00 -4.2522e-02 4.2486e-03 2.0429e-05 8.9793e-02 2.0231e-02 1.8877e-01 8.9608e-02 9.2177e-01 8.3210e-02 9.9901e-01 8.1637e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 474: 1.0250e+02 -4.0999e+00 -2.3209e+00 -4.0410e+00 -1.0079e+00 -4.2640e-02 4.2536e-03 2.0403e-05 8.9731e-02 2.0213e-02 1.8876e-01 8.9632e-02 9.2177e-01 8.3192e-02 9.9942e-01 8.1632e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 475: 1.0250e+02 -4.0999e+00 -2.3208e+00 -4.0409e+00 -1.0079e+00 -4.2882e-02 4.2576e-03 2.0375e-05 8.9666e-02 2.0190e-02 1.8866e-01 8.9718e-02 9.2160e-01 8.3218e-02 9.9931e-01 8.1622e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 476: 1.0250e+02 -4.0999e+00 -2.3207e+00 -4.0409e+00 -1.0080e+00 -4.2983e-02 4.2599e-03 2.0368e-05 8.9563e-02 2.0171e-02 1.8859e-01 8.9777e-02 9.2162e-01 8.3236e-02 9.9932e-01 8.1620e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 477: 1.0250e+02 -4.0999e+00 -2.3205e+00 -4.0410e+00 -1.0081e+00 -4.3022e-02 4.2570e-03 2.0364e-05 8.9440e-02 2.0166e-02 1.8860e-01 8.9785e-02 9.2171e-01 8.3236e-02 9.9940e-01 8.1633e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 478: 1.0250e+02 -4.0999e+00 -2.3203e+00 -4.0410e+00 -1.0080e+00 -4.3129e-02 4.2505e-03 2.0371e-05 8.9374e-02 2.0151e-02 1.8859e-01 8.9826e-02 9.2171e-01 8.3224e-02 9.9970e-01 8.1620e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 479: 1.0250e+02 -4.1000e+00 -2.3201e+00 -4.0410e+00 -1.0080e+00 -4.3186e-02 4.2440e-03 2.0373e-05 8.9355e-02 2.0133e-02 1.8858e-01 8.9837e-02 9.2168e-01 8.3214e-02 9.9991e-01 8.1621e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 480: 1.0250e+02 -4.1000e+00 -2.3198e+00 -4.0410e+00 -1.0080e+00 -4.3477e-02 4.2424e-03 2.0440e-05 8.9311e-02 2.0121e-02 1.8857e-01 8.9848e-02 9.2158e-01 8.3221e-02 9.9995e-01 8.1627e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 481: 1.0250e+02 -4.1000e+00 -2.3194e+00 -4.0410e+00 -1.0079e+00 -4.3647e-02 4.2358e-03 2.0479e-05 8.9315e-02 2.0096e-02 1.8851e-01 8.9865e-02 9.2159e-01 8.3197e-02 1.0002e+00 8.1642e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 482: 1.0250e+02 -4.1000e+00 -2.3188e+00 -4.0409e+00 -1.0079e+00 -4.3909e-02 4.2370e-03 2.0551e-05 8.9382e-02 2.0085e-02 1.8840e-01 8.9799e-02 9.2147e-01 8.3229e-02 1.0001e+00 8.1656e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 483: 1.0250e+02 -4.1000e+00 -2.3189e+00 -4.0409e+00 -1.0078e+00 -4.4169e-02 4.2467e-03 2.0587e-05 8.9377e-02 2.0054e-02 1.8838e-01 8.9943e-02 9.2130e-01 8.3237e-02 1.0003e+00 8.1650e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 484: 1.0250e+02 -4.1000e+00 -2.3188e+00 -4.0408e+00 -1.0078e+00 -4.4346e-02 4.2627e-03 2.0605e-05 8.9450e-02 2.0020e-02 1.8840e-01 9.0090e-02 9.2114e-01 8.3237e-02 1.0004e+00 8.1639e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 485: 1.0250e+02 -4.1000e+00 -2.3185e+00 -4.0408e+00 -1.0079e+00 -4.4414e-02 4.2737e-03 2.0594e-05 8.9541e-02 1.9999e-02 1.8842e-01 9.0237e-02 9.2116e-01 8.3227e-02 1.0004e+00 8.1641e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 486: 1.0250e+02 -4.1000e+00 -2.3183e+00 -4.0408e+00 -1.0080e+00 -4.4572e-02 4.2902e-03 2.0581e-05 8.9733e-02 1.9978e-02 1.8837e-01 9.0412e-02 9.2098e-01 8.3224e-02 1.0003e+00 8.1642e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 487: 1.0250e+02 -4.1000e+00 -2.3182e+00 -4.0407e+00 -1.0081e+00 -4.4698e-02 4.2979e-03 2.0560e-05 8.9822e-02 1.9954e-02 1.8827e-01 9.0744e-02 9.2114e-01 8.3212e-02 1.0003e+00 8.1644e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 488: 1.0250e+02 -4.1000e+00 -2.3180e+00 -4.0406e+00 -1.0081e+00 -4.4892e-02 4.3035e-03 2.0549e-05 8.9849e-02 1.9928e-02 1.8816e-01 9.1000e-02 9.2118e-01 8.3206e-02 1.0003e+00 8.1644e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 489: 1.0250e+02 -4.1000e+00 -2.3180e+00 -4.0406e+00 -1.0081e+00 -4.5037e-02 4.2987e-03 2.0515e-05 8.9843e-02 1.9906e-02 1.8815e-01 9.1260e-02 9.2116e-01 8.3190e-02 1.0001e+00 8.1633e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 490: 1.0250e+02 -4.1000e+00 -2.3179e+00 -4.0405e+00 -1.0081e+00 -4.5139e-02 4.2930e-03 2.0508e-05 8.9827e-02 1.9887e-02 1.8814e-01 9.1545e-02 9.2114e-01 8.3178e-02 9.9991e-01 8.1624e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 491: 1.0250e+02 -4.1000e+00 -2.3179e+00 -4.0405e+00 -1.0081e+00 -4.5107e-02 4.2871e-03 2.0490e-05 8.9765e-02 1.9855e-02 1.8814e-01 9.1702e-02 9.2089e-01 8.3179e-02 9.9986e-01 8.1624e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 492: 1.0250e+02 -4.1000e+00 -2.3178e+00 -4.0405e+00 -1.0080e+00 -4.5192e-02 4.2818e-03 2.0470e-05 8.9791e-02 1.9831e-02 1.8810e-01 9.1846e-02 9.2086e-01 8.3164e-02 9.9977e-01 8.1630e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 493: 1.0250e+02 -4.1000e+00 -2.3179e+00 -4.0406e+00 -1.0078e+00 -4.4968e-02 4.2782e-03 2.0452e-05 8.9797e-02 1.9804e-02 1.8806e-01 9.1987e-02 9.2080e-01 8.3146e-02 9.9982e-01 8.1627e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 494: 1.0250e+02 -4.1000e+00 -2.3180e+00 -4.0406e+00 -1.0078e+00 -4.4773e-02 4.2766e-03 2.0453e-05 8.9696e-02 1.9781e-02 1.8805e-01 9.2096e-02 9.2057e-01 8.3148e-02 9.9999e-01 8.1611e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 495: 1.0250e+02 -4.1000e+00 -2.3181e+00 -4.0408e+00 -1.0078e+00 -4.4647e-02 4.2798e-03 2.0446e-05 8.9661e-02 1.9763e-02 1.8804e-01 9.2155e-02 9.2039e-01 8.3137e-02 9.9999e-01 8.1599e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 496: 1.0250e+02 -4.1000e+00 -2.3182e+00 -4.0408e+00 -1.0079e+00 -4.4482e-02 4.2851e-03 2.0434e-05 8.9630e-02 1.9750e-02 1.8796e-01 9.2258e-02 9.2042e-01 8.3124e-02 1.0000e+00 8.1601e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 497: 1.0250e+02 -4.1000e+00 -2.3184e+00 -4.0409e+00 -1.0079e+00 -4.4175e-02 4.2866e-03 2.0423e-05 8.9656e-02 1.9743e-02 1.8789e-01 9.2225e-02 9.2017e-01 8.3126e-02 1.0002e+00 8.1616e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 498: 1.0250e+02 -4.1000e+00 -2.3187e+00 -4.0409e+00 -1.0079e+00 -4.3826e-02 4.2847e-03 2.0406e-05 8.9587e-02 1.9730e-02 1.8781e-01 9.2143e-02 9.2017e-01 8.3156e-02 1.0002e+00 8.1613e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 499: 1.0250e+02 -4.1000e+00 -2.3190e+00 -4.0409e+00 -1.0078e+00 -4.3529e-02 4.2806e-03 2.0397e-05 8.9653e-02 1.9712e-02 1.8779e-01 9.2107e-02 9.2028e-01 8.3172e-02 1.0004e+00 8.1607e-02</span> +<span class="r-out co"><span class="r-pr">#></span> 500: 1.0250e+02 -4.1000e+00 -2.3193e+00 -4.0409e+00 -1.0077e+00 -4.3241e-02 4.2787e-03 2.0390e-05 8.9759e-02 1.9689e-02 1.8773e-01 9.2021e-02 9.2029e-01 8.3203e-02 1.0006e+00 8.1613e-02</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-in"><span class="co"># The following takes a very long time but gives</span></span> +<span class="r-in"><span class="va">f_nlmixr_dfop_sfo_focei</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/nlmixr/man/nlmixr.html" class="external-link">nlmixr</a></span><span class="op">(</span><span class="va">f_mmkin_dfop_sfo</span>, est <span class="op">=</span> <span class="st">"focei"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> parameter labels from comments are typically ignored in non-interactive mode</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BBBB;">ℹ</span> Need to run with the source intact to parse comments</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → creating full model...</span> +<span class="r-msg co"><span class="r-pr">#></span> → pruning branches (`if`/`else`)...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → loading into <span style="color: #0000BB;">symengine</span> environment...</span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate jacobian</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate sensitivities</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(f)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → calculate ∂(R²)/∂(η)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in inner model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in EBE model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling inner model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → finding duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → optimizing duplicate expressions in FD model...</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling EBE model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> → compiling events FD model...</span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-msg co"><span class="r-pr">#></span> <span style="color: #00BB00;">✔</span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Needed Covariates:</span> +<span class="r-out co"><span class="r-pr">#></span> [1] "CMT"</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="font-weight: bold;">Key:</span> U: Unscaled Parameters; X: Back-transformed parameters; G: Gill difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> F: Forward difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> C: Central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> M: Mixed forward and central difference gradient approximation</span> +<span class="r-out co"><span class="r-pr">#></span> Unscaled parameters for Omegas=chol(solve(omega));</span> +<span class="r-out co"><span class="r-pr">#></span> Diagonals are transformed, as specified by foceiControl(diagXform=)</span> +<span class="r-out co"><span class="r-pr">#></span> |-----+---------------+-----------+-----------+-----------+-----------|</span> +<span class="r-out co"><span class="r-pr">#></span> | #| Objective Fun | parent_0 | log_k_m1 |f_parent_qlogis | log_k1 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| log_k2 | g_qlogis | sigma_low | rsd_high |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| o1 | o2 | o3 | o4 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| o5 | o6 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 1</span>| 496.69520 | 1.000 | -1.000 | -0.9393 | -0.9673 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.000 | -0.9214 | -0.9072 | -0.9199 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9082 | -0.8909 | -0.8969 | -0.8991 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8928 | -0.8991 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 496.6952 | 100.0 | -4.100 | -0.9400 | -2.400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.100 | -0.01100 | 0.7300 | 0.06700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6756 | 1.581 | 1.265 | 1.151 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.477 | 1.151 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 496.6952</span> | 100.0 | 0.01657 | 0.2809 | 0.09072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01657 | 0.4973 | 0.7300 | 0.06700 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6756 | 1.581 | 1.265 | 1.151 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.477 | 1.151 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | G| Gill Diff. | -72.99 | -3.907 | -0.8109 | 0.02803 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.841 | 0.006841 | -22.18 | -32.78 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.538 | -16.93 | -12.84 | -12.77 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -15.02 | -9.608 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 2</span>| 1346.5436 | 1.823 | -0.9559 | -0.9301 | -0.9677 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9792 | -0.9215 | -0.6570 | -0.5501 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9482 | -0.6999 | -0.7521 | -0.7551 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7234 | -0.7907 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 1346.5436 | 182.3 | -4.056 | -0.9314 | -2.400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.079 | -0.01100 | 0.8213 | 0.07939 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6486 | 1.883 | 1.449 | 1.317 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.728 | 1.276 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 1346.5436</span> | 182.3 | 0.01732 | 0.2826 | 0.09069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01692 | 0.4972 | 0.8213 | 0.07939 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6486 | 1.883 | 1.449 | 1.317 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.728 | 1.276 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 3</span>| 512.48246 | 1.082 | -0.9956 | -0.9384 | -0.9674 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9979 | -0.9214 | -0.8822 | -0.8830 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9122 | -0.8718 | -0.8824 | -0.8847 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8759 | -0.8883 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 512.48246 | 108.2 | -4.096 | -0.9391 | -2.400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.098 | -0.01100 | 0.7391 | 0.06824 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6729 | 1.611 | 1.284 | 1.167 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.502 | 1.163 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 512.48246</span> | 108.2 | 0.01665 | 0.2811 | 0.09072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01661 | 0.4973 | 0.7391 | 0.06824 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6729 | 1.611 | 1.284 | 1.167 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.502 | 1.163 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 4</span>| 495.95762 | 1.015 | -0.9992 | -0.9391 | -0.9673 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9996 | -0.9214 | -0.9027 | -0.9133 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9090 | -0.8874 | -0.8943 | -0.8965 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8898 | -0.8972 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 495.95762 | 101.5 | -4.099 | -0.9398 | -2.400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.100 | -0.01100 | 0.7316 | 0.06722 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6751 | 1.587 | 1.269 | 1.154 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.482 | 1.153 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 495.95762</span> | 101.5 | 0.01659 | 0.2809 | 0.09072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01658 | 0.4973 | 0.7316 | 0.06722 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6751 | 1.587 | 1.269 | 1.154 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.482 | 1.153 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 41.81 | -3.013 | -0.08916 | -0.3303 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.914 | 0.005472 | -23.39 | -29.38 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.465 | -17.07 | -12.49 | -12.74 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -15.23 | -9.735 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 5</span>| 495.32815 | 1.003 | -0.9984 | -0.9391 | -0.9673 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9991 | -0.9214 | -0.8962 | -0.9051 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9099 | -0.8826 | -0.8908 | -0.8930 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8855 | -0.8944 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 495.32815 | 100.3 | -4.098 | -0.9398 | -2.400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.099 | -0.01100 | 0.7340 | 0.06750 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6745 | 1.594 | 1.273 | 1.158 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.488 | 1.156 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 495.32815</span> | 100.3 | 0.01660 | 0.2809 | 0.09073 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01659 | 0.4973 | 0.7340 | 0.06750 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6745 | 1.594 | 1.273 | 1.158 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.488 | 1.156 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -47.70 | -3.739 | -0.6694 | -0.04580 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.870 | 0.006670 | -22.76 | -30.26 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.613 | -16.75 | -12.29 | -12.38 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -15.09 | -9.486 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 6</span>| 494.72051 | 1.016 | -0.9974 | -0.9389 | -0.9672 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9986 | -0.9214 | -0.8902 | -0.8971 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9109 | -0.8782 | -0.8876 | -0.8897 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8816 | -0.8919 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.72051 | 101.6 | -4.097 | -0.9397 | -2.400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.099 | -0.01100 | 0.7362 | 0.06777 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6738 | 1.601 | 1.277 | 1.162 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.494 | 1.159 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.72051</span> | 101.6 | 0.01662 | 0.2810 | 0.09073 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01660 | 0.4973 | 0.7362 | 0.06777 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6738 | 1.601 | 1.277 | 1.162 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.494 | 1.159 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 48.34 | -2.939 | -0.03847 | -0.3608 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.945 | 0.005434 | -20.90 | -26.17 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.821 | -17.00 | -12.53 | -12.70 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -15.56 | -9.587 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 7</span>| 494.15722 | 1.003 | -0.9966 | -0.9389 | -0.9671 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9981 | -0.9214 | -0.8845 | -0.8900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9119 | -0.8736 | -0.8842 | -0.8863 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8773 | -0.8893 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 494.15722 | 100.3 | -4.097 | -0.9396 | -2.400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.098 | -0.01100 | 0.7383 | 0.06800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6731 | 1.608 | 1.282 | 1.166 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.500 | 1.162 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 494.15722</span> | 100.3 | 0.01663 | 0.2810 | 0.09074 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01660 | 0.4973 | 0.7383 | 0.06800 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6731 | 1.608 | 1.282 | 1.166 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.500 | 1.162 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -50.36 | -3.770 | -0.7003 | -0.03307 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.882 | 0.006830 | -20.02 | -28.64 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.020 | -16.49 | -12.31 | -12.33 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -14.87 | -9.319 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 8</span>| 493.49185 | 1.015 | -0.9955 | -0.9387 | -0.9671 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9975 | -0.9214 | -0.8787 | -0.8818 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9128 | -0.8688 | -0.8806 | -0.8827 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8730 | -0.8866 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 493.49185 | 101.5 | -4.096 | -0.9395 | -2.400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.098 | -0.01100 | 0.7404 | 0.06828 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6725 | 1.616 | 1.286 | 1.170 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.507 | 1.165 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 493.49185</span> | 101.5 | 0.01665 | 0.2810 | 0.09074 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01661 | 0.4973 | 0.7404 | 0.06828 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6725 | 1.616 | 1.286 | 1.170 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.507 | 1.165 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 41.03 | -2.976 | -0.07989 | -0.3421 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.950 | 0.005619 | -20.95 | -25.58 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.377 | -16.59 | -11.95 | -12.23 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -14.73 | -9.398 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 9</span>| 492.95463 | 1.003 | -0.9946 | -0.9387 | -0.9670 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9969 | -0.9215 | -0.8725 | -0.8742 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9138 | -0.8639 | -0.8771 | -0.8790 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8686 | -0.8839 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 492.95463 | 100.3 | -4.095 | -0.9394 | -2.400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.097 | -0.01100 | 0.7427 | 0.06853 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6718 | 1.624 | 1.291 | 1.174 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.513 | 1.168 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 492.95463</span> | 100.3 | 0.01666 | 0.2810 | 0.09075 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01662 | 0.4973 | 0.7427 | 0.06853 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6718 | 1.624 | 1.291 | 1.174 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.513 | 1.168 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -49.97 | -3.772 | -0.7121 | -0.02926 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.890 | 0.006985 | -18.86 | -26.85 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.866 | -16.28 | -11.70 | -11.82 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -14.59 | -9.132 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 10</span>| 492.31444 | 1.015 | -0.9935 | -0.9385 | -0.9670 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9964 | -0.9215 | -0.8668 | -0.8662 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9147 | -0.8589 | -0.8735 | -0.8755 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8642 | -0.8811 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 492.31444 | 101.5 | -4.094 | -0.9393 | -2.400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.096 | -0.01100 | 0.7448 | 0.06880 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6712 | 1.632 | 1.295 | 1.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.520 | 1.172 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 492.31444</span> | 101.5 | 0.01668 | 0.2810 | 0.09075 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01663 | 0.4972 | 0.7448 | 0.06880 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6712 | 1.632 | 1.295 | 1.178 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.520 | 1.172 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 40.47 | -2.944 | -0.07505 | -0.3464 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.962 | 0.005707 | -18.58 | -22.75 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.454 | -16.50 | -11.93 | -12.14 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -15.04 | -9.193 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 11</span>| 491.79472 | 1.003 | -0.9926 | -0.9385 | -0.9669 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9957 | -0.9215 | -0.8609 | -0.8590 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9158 | -0.8537 | -0.8697 | -0.8716 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8594 | -0.8781 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 491.79472 | 100.3 | -4.093 | -0.9392 | -2.400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.096 | -0.01100 | 0.7469 | 0.06904 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6705 | 1.640 | 1.300 | 1.183 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.527 | 1.175 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 491.79472</span> | 100.3 | 0.01670 | 0.2811 | 0.09076 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01664 | 0.4972 | 0.7469 | 0.06904 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6705 | 1.640 | 1.300 | 1.183 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.527 | 1.175 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -48.84 | -3.756 | -0.7183 | -0.02810 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.902 | 0.007122 | -19.51 | -25.13 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.711 | -16.03 | -11.73 | -11.80 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -14.28 | -8.965 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 12</span>| 491.12641 | 1.014 | -0.9913 | -0.9383 | -0.9669 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9951 | -0.9215 | -0.8546 | -0.8511 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9167 | -0.8483 | -0.8658 | -0.8677 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8546 | -0.8752 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 491.12641 | 101.4 | -4.091 | -0.9390 | -2.400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.095 | -0.01100 | 0.7492 | 0.06931 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6699 | 1.648 | 1.305 | 1.187 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.534 | 1.178 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 491.12641</span> | 101.4 | 0.01672 | 0.2811 | 0.09076 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01665 | 0.4972 | 0.7492 | 0.06931 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6699 | 1.648 | 1.305 | 1.187 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.534 | 1.178 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 34.57 | -2.950 | -0.1076 | -0.3310 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.967 | 0.005897 | -18.06 | -21.71 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.154 | -16.24 | -11.62 | -11.87 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -14.73 | -8.995 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 13</span>| 490.65951 | 1.002 | -0.9903 | -0.9382 | -0.9668 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9944 | -0.9215 | -0.8485 | -0.8438 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9178 | -0.8429 | -0.8619 | -0.8637 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8496 | -0.8721 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 490.65951 | 100.2 | -4.090 | -0.9390 | -2.399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.094 | -0.01100 | 0.7514 | 0.06955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6692 | 1.657 | 1.310 | 1.192 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.541 | 1.182 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 490.65951</span> | 100.2 | 0.01673 | 0.2811 | 0.09077 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01667 | 0.4972 | 0.7514 | 0.06955 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6692 | 1.657 | 1.310 | 1.192 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.541 | 1.182 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -50.76 | -3.759 | -0.7472 | -0.01668 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.908 | 0.007323 | -16.70 | -21.90 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.094 | -15.72 | -11.38 | -11.47 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -14.04 | -8.745 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 14</span>| 490.01300 | 1.014 | -0.9891 | -0.9380 | -0.9667 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9937 | -0.9215 | -0.8428 | -0.8366 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9189 | -0.8372 | -0.8579 | -0.8596 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8446 | -0.8690 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 490.013 | 101.4 | -4.089 | -0.9388 | -2.399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.094 | -0.01100 | 0.7535 | 0.06979 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6684 | 1.666 | 1.315 | 1.196 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.549 | 1.186 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 490.013</span> | 101.4 | 0.01676 | 0.2811 | 0.09077 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01668 | 0.4972 | 0.7535 | 0.06979 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6684 | 1.666 | 1.315 | 1.196 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.549 | 1.186 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 34.25 | -2.890 | -0.09666 | -0.3362 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.973 | 0.006003 | -17.09 | -20.19 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 3.007 | -15.95 | -11.25 | -11.56 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -14.42 | -8.788 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 15</span>| 489.51603 | 1.003 | -0.9880 | -0.9380 | -0.9666 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9930 | -0.9215 | -0.8366 | -0.8294 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9200 | -0.8313 | -0.8537 | -0.8553 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8392 | -0.8658 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 489.51603 | 100.3 | -4.088 | -0.9388 | -2.399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.093 | -0.01100 | 0.7558 | 0.07003 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6677 | 1.675 | 1.320 | 1.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.556 | 1.189 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 489.51603</span> | 100.3 | 0.01677 | 0.2812 | 0.09078 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01669 | 0.4972 | 0.7558 | 0.07003 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6677 | 1.675 | 1.320 | 1.201 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.556 | 1.189 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -45.29 | -3.673 | -0.7179 | -0.03084 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.907 | 0.007423 | -17.34 | -21.86 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.565 | -15.52 | -11.05 | -11.19 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -14.28 | -8.545 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 16</span>| 488.89410 | 1.014 | -0.9866 | -0.9377 | -0.9666 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9922 | -0.9215 | -0.8304 | -0.8220 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9210 | -0.8254 | -0.8495 | -0.8510 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8337 | -0.8625 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 488.8941 | 101.4 | -4.087 | -0.9385 | -2.399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.092 | -0.01100 | 0.7580 | 0.07028 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6670 | 1.685 | 1.325 | 1.206 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.565 | 1.193 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 488.8941</span> | 101.4 | 0.01680 | 0.2812 | 0.09079 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01670 | 0.4972 | 0.7580 | 0.07028 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6670 | 1.685 | 1.325 | 1.206 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.565 | 1.193 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 32.56 | -2.827 | -0.09853 | -0.3366 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.968 | 0.006143 | -15.42 | -18.16 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.733 | -15.52 | -10.94 | -11.25 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -14.13 | -8.583 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 17</span>| 488.48678 | 1.002 | -0.9855 | -0.9377 | -0.9664 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9915 | -0.9215 | -0.8246 | -0.8152 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9220 | -0.8195 | -0.8454 | -0.8468 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8284 | -0.8593 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 488.48678 | 100.2 | -4.086 | -0.9385 | -2.399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.091 | -0.01100 | 0.7601 | 0.07051 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6663 | 1.694 | 1.331 | 1.211 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.572 | 1.197 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 488.48678</span> | 100.2 | 0.01681 | 0.2812 | 0.09080 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01671 | 0.4972 | 0.7601 | 0.07051 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6663 | 1.694 | 1.331 | 1.211 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.572 | 1.197 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -50.86 | -3.681 | -0.7723 |-0.0007467 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.892 | 0.007742 | -16.40 | -20.55 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.306 | -15.16 | -10.65 | -10.82 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -14.00 | -8.331 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 18</span>| 487.81394 | 1.012 | -0.9841 | -0.9374 | -0.9664 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9907 | -0.9215 | -0.8186 | -0.8083 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9229 | -0.8132 | -0.8411 | -0.8424 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8225 | -0.8558 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 487.81394 | 101.2 | -4.084 | -0.9383 | -2.399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.091 | -0.01100 | 0.7623 | 0.07074 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6657 | 1.704 | 1.336 | 1.216 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.581 | 1.201 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 487.81394</span> | 101.2 | 0.01684 | 0.2812 | 0.09080 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01673 | 0.4972 | 0.7623 | 0.07074 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6657 | 1.704 | 1.336 | 1.216 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.581 | 1.201 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 24.73 | -2.818 | -0.1513 | -0.3103 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.952 | 0.006413 | -14.43 | -16.89 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.774 | -15.21 | -10.56 | -10.91 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -13.80 | -8.354 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 19</span>| 487.41354 | 1.002 | -0.9829 | -0.9374 | -0.9663 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9898 | -0.9215 | -0.8126 | -0.8013 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9240 | -0.8068 | -0.8367 | -0.8378 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8167 | -0.8523 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 487.41354 | 100.2 | -4.083 | -0.9382 | -2.399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.090 | -0.01100 | 0.7645 | 0.07098 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6649 | 1.714 | 1.342 | 1.221 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.590 | 1.205 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 487.41354</span> | 100.2 | 0.01686 | 0.2813 | 0.09082 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01674 | 0.4972 | 0.7645 | 0.07098 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6649 | 1.714 | 1.342 | 1.221 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.590 | 1.205 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -49.04 | -3.605 | -0.7738 | -0.005231 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.885 | 0.007887 | -13.75 | -19.14 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.153 | -14.90 | -10.33 | -10.54 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -13.68 | -8.125 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 20</span>| 486.77105 | 1.012 | -0.9814 | -0.9371 | -0.9662 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9889 | -0.9215 | -0.8076 | -0.7947 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9250 | -0.7999 | -0.8321 | -0.8330 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8104 | -0.8486 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 486.77105 | 101.2 | -4.081 | -0.9380 | -2.399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.089 | -0.01100 | 0.7664 | 0.07119 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6643 | 1.725 | 1.347 | 1.227 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.599 | 1.209 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 486.77105</span> | 101.2 | 0.01688 | 0.2813 | 0.09082 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01676 | 0.4972 | 0.7664 | 0.07119 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6643 | 1.725 | 1.347 | 1.227 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.599 | 1.209 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 24.27 | -2.713 | -0.1438 | -0.3142 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.939 | 0.006562 | -14.18 | -16.12 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.525 | -14.86 | -10.17 | -10.57 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -13.46 | -8.131 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 21</span>| 486.40106 | 1.002 | -0.9802 | -0.9371 | -0.9661 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9881 | -0.9215 | -0.8015 | -0.7878 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9261 | -0.7935 | -0.8277 | -0.8285 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8046 | -0.8452 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 486.40106 | 100.2 | -4.080 | -0.9379 | -2.399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.088 | -0.01100 | 0.7686 | 0.07143 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6635 | 1.735 | 1.353 | 1.232 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.608 | 1.213 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 486.40106</span> | 100.2 | 0.01690 | 0.2813 | 0.09083 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01677 | 0.4972 | 0.7686 | 0.07143 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6635 | 1.735 | 1.353 | 1.232 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.608 | 1.213 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -49.43 | -3.533 | -0.7907 | 0.002583 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.861 | 0.008122 | -12.85 | -17.77 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.313 | -14.52 | -9.868 | -10.18 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -13.34 | -7.899 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 22</span>| 485.77865 | 1.012 | -0.9786 | -0.9368 | -0.9660 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9871 | -0.9215 | -0.7966 | -0.7818 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9271 | -0.7864 | -0.8231 | -0.8237 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7980 | -0.8414 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 485.77865 | 101.2 | -4.079 | -0.9376 | -2.399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.087 | -0.01100 | 0.7704 | 0.07163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6629 | 1.746 | 1.359 | 1.238 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.617 | 1.217 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 485.77865</span> | 101.2 | 0.01693 | 0.2814 | 0.09084 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01679 | 0.4972 | 0.7704 | 0.07163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6629 | 1.746 | 1.359 | 1.238 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.617 | 1.217 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 23.77 | -2.587 | -0.1355 | -0.3176 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.913 | 0.006717 | -13.39 | -15.00 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.211 | -14.53 | -9.747 | -10.22 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -13.16 | -7.915 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 23</span>| 485.42886 | 1.002 | -0.9775 | -0.9367 | -0.9659 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9862 | -0.9215 | -0.7907 | -0.7751 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9281 | -0.7799 | -0.8187 | -0.8190 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7921 | -0.8378 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 485.42886 | 100.2 | -4.077 | -0.9376 | -2.399 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.086 | -0.01100 | 0.7725 | 0.07185 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6622 | 1.757 | 1.364 | 1.243 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.626 | 1.221 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 485.42886</span> | 100.2 | 0.01695 | 0.2814 | 0.09085 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01680 | 0.4972 | 0.7725 | 0.07185 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6622 | 1.757 | 1.364 | 1.243 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.626 | 1.221 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -48.95 | -3.431 | -0.7980 | 0.007511 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.828 | 0.008340 | -12.05 | -16.59 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.177 | -14.27 | -9.567 | -9.843 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -12.98 | -7.655 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 24</span>| 484.82183 | 1.012 | -0.9759 | -0.9364 | -0.9658 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9852 | -0.9215 | -0.7861 | -0.7697 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9290 | -0.7723 | -0.8141 | -0.8141 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7852 | -0.8339 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 484.82183 | 101.2 | -4.076 | -0.9373 | -2.398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.085 | -0.01100 | 0.7742 | 0.07203 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6616 | 1.769 | 1.370 | 1.249 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.636 | 1.226 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 484.82183</span> | 101.2 | 0.01698 | 0.2814 | 0.09086 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01682 | 0.4972 | 0.7742 | 0.07203 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6616 | 1.769 | 1.370 | 1.249 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.636 | 1.226 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 22.05 | -2.460 | -0.1372 | -0.3150 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.875 | 0.006918 | -12.51 | -13.87 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.059 | -14.26 | -9.441 | -9.910 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -12.81 | -7.688 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 25</span>| 484.49026 | 1.002 | -0.9747 | -0.9363 | -0.9656 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9843 | -0.9215 | -0.7802 | -0.7632 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9300 | -0.7655 | -0.8095 | -0.8093 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7791 | -0.8302 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 484.49026 | 100.2 | -4.075 | -0.9372 | -2.398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.084 | -0.01100 | 0.7764 | 0.07225 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6609 | 1.779 | 1.376 | 1.254 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.645 | 1.230 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 484.49026</span> | 100.2 | 0.01700 | 0.2815 | 0.09087 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01684 | 0.4972 | 0.7764 | 0.07225 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6609 | 1.779 | 1.376 | 1.254 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.645 | 1.230 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -48.40 | -3.314 | -0.8046 | 0.01082 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.785 | 0.008564 | -11.34 | -13.90 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.095 | -13.95 | -9.157 | -9.483 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -12.66 | -7.448 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 26</span>| 483.91316 | 1.012 | -0.9731 | -0.9360 | -0.9656 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9832 | -0.9215 | -0.7758 | -0.7593 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9309 | -0.7575 | -0.8048 | -0.8042 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7719 | -0.8261 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 483.91316 | 101.2 | -4.073 | -0.9369 | -2.398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.083 | -0.01100 | 0.7780 | 0.07238 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6603 | 1.792 | 1.382 | 1.260 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.656 | 1.235 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 483.91316</span> | 101.2 | 0.01702 | 0.2815 | 0.09088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01685 | 0.4972 | 0.7780 | 0.07238 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6603 | 1.792 | 1.382 | 1.260 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.656 | 1.235 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 21.71 | -2.295 | -0.1241 | -0.3190 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.824 | 0.007081 | -13.14 | -14.20 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.713 | -13.92 | -9.049 | -9.560 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -12.44 | -7.439 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 27</span>| 483.53972 | 1.003 | -0.9719 | -0.9359 | -0.9654 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9822 | -0.9215 | -0.7695 | -0.7529 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9317 | -0.7501 | -0.8002 | -0.7993 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7653 | -0.8222 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 483.53972 | 100.3 | -4.072 | -0.9368 | -2.398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.082 | -0.01100 | 0.7803 | 0.07259 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6598 | 1.804 | 1.388 | 1.266 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.666 | 1.239 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 483.53972</span> | 100.3 | 0.01705 | 0.2815 | 0.09089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01687 | 0.4972 | 0.7803 | 0.07259 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6598 | 1.804 | 1.388 | 1.266 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.666 | 1.239 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -41.33 | -3.086 | -0.7421 | -0.01550 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.732 | 0.008667 | -12.24 | -14.31 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.879 | -13.57 | -8.704 | -9.151 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -12.31 | -7.231 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 28</span>| 483.02129 | 1.012 | -0.9704 | -0.9356 | -0.9653 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9811 | -0.9215 | -0.7639 | -0.7482 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9323 | -0.7422 | -0.7957 | -0.7943 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7582 | -0.8182 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 483.02129 | 101.2 | -4.070 | -0.9365 | -2.398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.081 | -0.01100 | 0.7823 | 0.07275 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6594 | 1.816 | 1.393 | 1.271 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.676 | 1.244 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 483.02129</span> | 101.2 | 0.01707 | 0.2816 | 0.09090 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01689 | 0.4972 | 0.7823 | 0.07275 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6594 | 1.816 | 1.393 | 1.271 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.676 | 1.244 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 24.99 | -2.064 | -0.07177 | -0.3414 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.768 | 0.007186 | -12.35 | -13.09 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.619 | -13.63 | -8.749 | -9.199 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -12.40 | -7.209 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 29</span>| 482.63111 | 1.003 | -0.9692 | -0.9355 | -0.9651 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9800 | -0.9215 | -0.7579 | -0.7429 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9329 | -0.7344 | -0.7911 | -0.7893 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7510 | -0.8142 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 482.63111 | 100.3 | -4.069 | -0.9364 | -2.398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.080 | -0.01100 | 0.7845 | 0.07293 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6589 | 1.829 | 1.399 | 1.277 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.687 | 1.249 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 482.63111</span> | 100.3 | 0.01709 | 0.2816 | 0.09092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01691 | 0.4972 | 0.7845 | 0.07293 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6589 | 1.829 | 1.399 | 1.277 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.687 | 1.249 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -36.55 | -2.873 | -0.6941 | -0.03251 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.664 | 0.008820 | -11.56 | -13.31 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.468 | -13.22 | -8.319 | -8.815 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -11.93 | -7.014 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 30</span>| 482.15860 | 1.013 | -0.9679 | -0.9352 | -0.9650 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9789 | -0.9215 | -0.7525 | -0.7387 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9332 | -0.7261 | -0.7866 | -0.7843 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7435 | -0.8100 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 482.1586 | 101.3 | -4.068 | -0.9361 | -2.398 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.079 | -0.01100 | 0.7865 | 0.07307 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6587 | 1.842 | 1.405 | 1.283 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.698 | 1.253 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 482.1586</span> | 101.3 | 0.01711 | 0.2817 | 0.09093 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01693 | 0.4972 | 0.7865 | 0.07307 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6587 | 1.842 | 1.405 | 1.283 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.698 | 1.253 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 26.18 | -1.853 | -0.03641 | -0.3540 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.697 | 0.007343 | -10.35 | -10.94 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.762 | -13.15 | -8.194 | -8.841 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -11.73 | -7.013 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 31</span>| 481.77253 | 1.004 | -0.9667 | -0.9350 | -0.9648 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9778 | -0.9215 | -0.7477 | -0.7350 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9339 | -0.7174 | -0.7818 | -0.7789 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7358 | -0.8055 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 481.77253 | 100.4 | -4.067 | -0.9360 | -2.397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.078 | -0.01100 | 0.7882 | 0.07320 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6583 | 1.855 | 1.411 | 1.289 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.709 | 1.259 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 481.77253</span> | 100.4 | 0.01713 | 0.2817 | 0.09095 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01695 | 0.4972 | 0.7882 | 0.07320 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6583 | 1.855 | 1.411 | 1.289 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.709 | 1.259 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -33.42 | -2.468 | -0.6588 | -0.04495 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.582 | 0.009000 | -9.278 | -10.93 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 2.073 | -12.89 | -7.995 | -8.451 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -11.53 | -6.784 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 32</span>| 481.33405 | 1.012 | -0.9656 | -0.9347 | -0.9646 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9766 | -0.9215 | -0.7446 | -0.7329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9352 | -0.7079 | -0.7769 | -0.7733 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7275 | -0.8008 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 481.33405 | 101.2 | -4.066 | -0.9357 | -2.397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.077 | -0.01100 | 0.7894 | 0.07326 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6574 | 1.870 | 1.417 | 1.296 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.721 | 1.264 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 481.33405</span> | 101.2 | 0.01715 | 0.2818 | 0.09096 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01697 | 0.4972 | 0.7894 | 0.07326 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6574 | 1.870 | 1.417 | 1.296 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.721 | 1.264 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 23.32 | -1.710 | -0.03967 | -0.3452 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.599 | 0.007614 | -9.890 | -10.44 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.650 | -12.78 | -7.841 | -8.441 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -11.31 | -6.748 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 33</span>| 480.95912 | 1.004 | -0.9646 | -0.9346 | -0.9644 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9754 | -0.9215 | -0.7406 | -0.7300 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9364 | -0.6985 | -0.7720 | -0.7677 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7193 | -0.7960 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.95912 | 100.4 | -4.065 | -0.9356 | -2.397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.075 | -0.01100 | 0.7908 | 0.07336 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6566 | 1.885 | 1.424 | 1.302 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.734 | 1.270 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.95912</span> | 100.4 | 0.01717 | 0.2818 | 0.09098 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01699 | 0.4972 | 0.7908 | 0.07336 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6566 | 1.885 | 1.424 | 1.302 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.734 | 1.270 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -30.38 | -2.273 | -0.6168 | -0.05646 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.481 | 0.009185 | -8.899 | -11.86 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.510 | -12.49 | -7.578 | -8.069 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -11.13 | -6.546 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 34</span>| 480.53887 | 1.012 | -0.9637 | -0.9342 | -0.9642 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9743 | -0.9216 | -0.7379 | -0.7267 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9369 | -0.6888 | -0.7673 | -0.7623 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7109 | -0.7912 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.53887 | 101.2 | -4.064 | -0.9352 | -2.397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.074 | -0.01100 | 0.7918 | 0.07347 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6562 | 1.901 | 1.429 | 1.308 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.746 | 1.275 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.53887</span> | 101.2 | 0.01719 | 0.2819 | 0.09100 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01700 | 0.4972 | 0.7918 | 0.07347 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6562 | 1.901 | 1.429 | 1.308 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.746 | 1.275 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 23.40 | -1.545 | -0.009684 | -0.3499 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.497 | 0.007817 | -10.78 | -11.16 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.267 | -12.36 | -7.423 | -8.042 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -10.90 | -6.497 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 35</span>| 480.15983 | 1.005 | -0.9631 | -0.9341 | -0.9640 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9733 | -0.9216 | -0.7332 | -0.7223 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9371 | -0.6793 | -0.7629 | -0.7571 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7029 | -0.7866 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.15983 | 100.5 | -4.063 | -0.9351 | -2.397 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.073 | -0.01100 | 0.7935 | 0.07362 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6561 | 1.916 | 1.435 | 1.314 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.758 | 1.280 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.15983</span> | 100.5 | 0.01720 | 0.2819 | 0.09102 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01702 | 0.4972 | 0.7935 | 0.07362 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6561 | 1.916 | 1.435 | 1.314 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.758 | 1.280 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -28.57 | -2.381 | -0.5845 | -0.05882 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.378 | 0.009420 | -9.960 | -11.12 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.408 | -12.08 | -7.201 | -7.708 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -10.66 | -6.274 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 36</span>| 479.76525 | 1.013 | -0.9621 | -0.9338 | -0.9638 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9724 | -0.9216 | -0.7274 | -0.7189 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9370 | -0.6698 | -0.7590 | -0.7523 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6950 | -0.7821 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.76525 | 101.3 | -4.062 | -0.9349 | -2.396 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.072 | -0.01100 | 0.7956 | 0.07373 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6562 | 1.931 | 1.440 | 1.320 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.770 | 1.286 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.76525</span> | 101.3 | 0.01721 | 0.2819 | 0.09104 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01704 | 0.4972 | 0.7956 | 0.07373 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6562 | 1.931 | 1.440 | 1.320 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.770 | 1.286 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 25.60 | -1.145 | 0.04744 | -0.3638 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.405 | 0.007969 | -8.937 | -9.159 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.481 | -11.97 | -7.076 | -7.721 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -10.46 | -6.241 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 37</span>| 479.40619 | 1.005 | -0.9617 | -0.9337 | -0.9635 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9714 | -0.9216 | -0.7231 | -0.7171 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9376 | -0.6597 | -0.7546 | -0.7470 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6867 | -0.7774 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.40619 | 100.5 | -4.062 | -0.9348 | -2.396 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.071 | -0.01100 | 0.7972 | 0.07380 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6558 | 1.947 | 1.445 | 1.326 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.782 | 1.291 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.40619</span> | 100.5 | 0.01722 | 0.2820 | 0.09107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01705 | 0.4972 | 0.7972 | 0.07380 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6558 | 1.947 | 1.445 | 1.326 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.782 | 1.291 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -26.68 | -2.255 | -0.5492 | -0.06756 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.289 | 0.009576 | -8.071 | -10.65 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.114 | -11.68 | -6.840 | -7.373 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -10.30 | -6.055 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 38</span>| 479.03445 | 1.012 | -0.9610 | -0.9335 | -0.9633 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9705 | -0.9216 | -0.7212 | -0.7148 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9376 | -0.6492 | -0.7503 | -0.7416 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6779 | -0.7724 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 479.03445 | 101.2 | -4.061 | -0.9345 | -2.396 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.071 | -0.01100 | 0.7979 | 0.07387 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6558 | 1.963 | 1.451 | 1.332 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.795 | 1.297 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 479.03445</span> | 101.2 | 0.01723 | 0.2820 | 0.09109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01707 | 0.4972 | 0.7979 | 0.07387 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6558 | 1.963 | 1.451 | 1.332 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.795 | 1.297 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 22.12 | -1.081 | 0.03630 | -0.3485 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.311 | 0.008233 | -8.610 | -8.856 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.385 | -11.53 | -6.694 | -7.351 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -10.05 | -5.987 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 39</span>| 478.70046 | 1.005 | -0.9607 | -0.9334 | -0.9629 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9697 | -0.9216 | -0.7185 | -0.7124 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9378 | -0.6386 | -0.7461 | -0.7363 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6692 | -0.7674 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.70046 | 100.5 | -4.061 | -0.9345 | -2.396 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.070 | -0.01100 | 0.7989 | 0.07395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6557 | 1.980 | 1.456 | 1.338 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.808 | 1.302 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.70046</span> | 100.5 | 0.01724 | 0.2820 | 0.09112 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01708 | 0.4972 | 0.7989 | 0.07395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6557 | 1.980 | 1.456 | 1.338 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.808 | 1.302 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -26.51 | -2.193 | -0.5308 | -0.05813 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.191 | 0.009843 | -9.246 | -10.25 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.049 | -11.25 | -6.459 | -7.012 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -9.842 | -5.790 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 40</span>| 478.33460 | 1.012 | -0.9602 | -0.9332 | -0.9627 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9690 | -0.9216 | -0.7136 | -0.7111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9376 | -0.6278 | -0.7425 | -0.7314 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6607 | -0.7626 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.3346 | 101.2 | -4.060 | -0.9343 | -2.395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.069 | -0.01100 | 0.8007 | 0.07400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6558 | 1.997 | 1.461 | 1.344 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.820 | 1.308 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.3346</span> | 101.2 | 0.01724 | 0.2821 | 0.09114 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01709 | 0.4972 | 0.8007 | 0.07400 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6558 | 1.997 | 1.461 | 1.344 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.820 | 1.308 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 20.00 | -1.246 | 0.04282 | -0.3358 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.228 | 0.008460 | -8.250 | -8.533 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.305 | -11.09 | -6.335 | -6.999 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -9.637 | -5.739 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 41</span>| 478.02904 | 1.005 | -0.9595 | -0.9333 | -0.9623 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9683 | -0.9217 | -0.7087 | -0.7092 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9377 | -0.6173 | -0.7388 | -0.7264 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6523 | -0.7577 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 478.02904 | 100.5 | -4.060 | -0.9343 | -2.395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.068 | -0.01100 | 0.8025 | 0.07406 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6557 | 2.014 | 1.466 | 1.350 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.833 | 1.314 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 478.02904</span> | 100.5 | 0.01726 | 0.2820 | 0.09117 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01711 | 0.4972 | 0.8025 | 0.07406 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6557 | 2.014 | 1.466 | 1.350 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.833 | 1.314 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -28.91 | -2.133 | -0.5430 | -0.03427 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.114 | 0.01012 | -7.324 | -9.914 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9278 | -10.81 | -6.119 | -6.673 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -9.457 | -5.557 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 42</span>| 477.67480 | 1.012 | -0.9587 | -0.9331 | -0.9620 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9677 | -0.9217 | -0.7077 | -0.7075 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9374 | -0.6060 | -0.7354 | -0.7215 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6433 | -0.7527 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 477.6748 | 101.2 | -4.059 | -0.9342 | -2.395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.068 | -0.01100 | 0.8028 | 0.07412 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6559 | 2.032 | 1.470 | 1.355 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.846 | 1.319 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 477.6748</span> | 101.2 | 0.01727 | 0.2821 | 0.09120 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01712 | 0.4972 | 0.8028 | 0.07412 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6559 | 2.032 | 1.470 | 1.355 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.846 | 1.319 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 17.58 | -1.074 | 0.03251 | -0.3151 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.162 | 0.008688 | -9.226 | -9.481 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9303 | -10.65 | -6.004 | -6.660 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -9.223 | -5.492 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 43</span>| 477.36674 | 1.005 | -0.9586 | -0.9332 | -0.9617 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9672 | -0.9217 | -0.7028 | -0.7029 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9362 | -0.5954 | -0.7323 | -0.7170 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6350 | -0.7479 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 477.36674 | 100.5 | -4.059 | -0.9343 | -2.394 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.067 | -0.01100 | 0.8046 | 0.07427 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6567 | 2.048 | 1.474 | 1.361 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.858 | 1.325 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 477.36674</span> | 100.5 | 0.01727 | 0.2821 | 0.09123 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01713 | 0.4972 | 0.8046 | 0.07427 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6567 | 2.048 | 1.474 | 1.361 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.858 | 1.325 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -26.86 | -1.999 | -0.5088 | -0.02993 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.056 | 0.01029 | -6.930 | -7.943 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.123 | -10.40 | -5.776 | -6.354 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -9.032 | -5.321 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 44</span>| 477.05158 | 1.012 | -0.9583 | -0.9331 | -0.9614 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9667 | -0.9217 | -0.6985 | -0.7029 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9357 | -0.5841 | -0.7296 | -0.7125 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6265 | -0.7430 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 477.05158 | 101.2 | -4.058 | -0.9342 | -2.394 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.067 | -0.01100 | 0.8062 | 0.07427 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6570 | 2.066 | 1.477 | 1.366 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.871 | 1.331 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 477.05158</span> | 101.2 | 0.01728 | 0.2821 | 0.09126 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01713 | 0.4972 | 0.8062 | 0.07427 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6570 | 2.066 | 1.477 | 1.366 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.871 | 1.331 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 21.59 | -0.9080 | 0.1072 | -0.3377 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.120 | 0.008656 | -8.076 | -8.919 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8940 | -10.23 | -5.724 | -6.385 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -8.830 | -5.273 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 45</span>| 476.75116 | 1.006 | -0.9582 | -0.9333 | -0.9610 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9662 | -0.9217 | -0.6961 | -0.7025 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9353 | -0.5723 | -0.7265 | -0.7076 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6174 | -0.7378 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.75116 | 100.6 | -4.058 | -0.9343 | -2.394 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.066 | -0.01100 | 0.8070 | 0.07428 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6573 | 2.085 | 1.481 | 1.371 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.884 | 1.337 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.75116</span> | 100.6 | 0.01728 | 0.2820 | 0.09129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01714 | 0.4972 | 0.8070 | 0.07428 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6573 | 2.085 | 1.481 | 1.371 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.884 | 1.337 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -19.26 | -1.806 | -0.3949 | -0.06769 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.006 | 0.01017 | -6.717 | -7.715 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.115 | -9.949 | -5.529 | -6.080 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -8.599 | -5.083 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 46</span>| 476.47529 | 1.013 | -0.9577 | -0.9333 | -0.9608 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9657 | -0.9218 | -0.6941 | -0.7020 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9354 | -0.5606 | -0.7233 | -0.7027 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6086 | -0.7326 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.47529 | 101.3 | -4.058 | -0.9343 | -2.393 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.066 | -0.01100 | 0.8078 | 0.07430 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6573 | 2.103 | 1.485 | 1.377 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.897 | 1.342 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.47529</span> | 101.3 | 0.01729 | 0.2820 | 0.09132 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01715 | 0.4972 | 0.8078 | 0.07430 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6573 | 2.103 | 1.485 | 1.377 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.897 | 1.342 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 23.23 | -0.7393 | 0.1467 | -0.3435 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.063 | 0.008714 | -6.650 | -7.604 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.072 | -9.778 | -5.421 | -6.068 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -8.413 | -5.023 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 47</span>| 476.20958 | 1.007 | -0.9575 | -0.9335 | -0.9604 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9651 | -0.9218 | -0.6949 | -0.7035 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9364 | -0.5488 | -0.7198 | -0.6977 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5996 | -0.7274 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 476.20958 | 100.7 | -4.058 | -0.9345 | -2.393 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.065 | -0.01100 | 0.8075 | 0.07425 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6566 | 2.122 | 1.490 | 1.383 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.910 | 1.349 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 476.20958</span> | 100.7 | 0.01729 | 0.2820 | 0.09135 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01716 | 0.4972 | 0.8075 | 0.07425 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6566 | 2.122 | 1.490 | 1.383 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.910 | 1.349 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -16.91 | -1.652 | -0.3580 | -0.07063 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9392 | 0.01022 | -6.706 | -7.708 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9788 | -9.498 | -5.202 | -5.742 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -8.208 | -4.851 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 48</span>| 475.96032 | 1.013 | -0.9572 | -0.9335 | -0.9601 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9647 | -0.9218 | -0.6944 | -0.7034 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9370 | -0.5368 | -0.7166 | -0.6928 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5905 | -0.7221 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.96032 | 101.3 | -4.057 | -0.9346 | -2.393 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.065 | -0.01100 | 0.8077 | 0.07425 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6562 | 2.141 | 1.494 | 1.388 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.924 | 1.355 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.96032</span> | 101.3 | 0.01730 | 0.2820 | 0.09138 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01717 | 0.4972 | 0.8077 | 0.07425 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6562 | 2.141 | 1.494 | 1.388 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.924 | 1.355 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 22.21 | -0.6469 | 0.1490 | -0.3297 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9912 | 0.008804 | -6.697 | -7.730 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.011 | -9.295 | -5.014 | -5.737 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -7.990 | -4.768 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 49</span>| 475.69232 | 1.007 | -0.9579 | -0.9338 | -0.9597 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9645 | -0.9219 | -0.6939 | -0.7032 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9375 | -0.5243 | -0.7149 | -0.6885 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5813 | -0.7168 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.69232 | 100.7 | -4.058 | -0.9348 | -2.392 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.064 | -0.01100 | 0.8078 | 0.07426 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6559 | 2.161 | 1.496 | 1.393 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.937 | 1.361 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.69232</span> | 100.7 | 0.01729 | 0.2819 | 0.09141 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01717 | 0.4972 | 0.8078 | 0.07426 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6559 | 2.161 | 1.496 | 1.393 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.937 | 1.361 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -16.63 | -1.703 | -0.3428 | -0.06069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9074 | 0.01024 | -7.409 | -9.759 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6668 | -9.063 | -4.970 | -5.451 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -7.786 | -4.607 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 50</span>| 475.41012 | 1.012 | -0.9580 | -0.9340 | -0.9594 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9645 | -0.9219 | -0.6912 | -0.6928 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9358 | -0.5138 | -0.7150 | -0.6862 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5743 | -0.7128 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.41012 | 101.2 | -4.058 | -0.9351 | -2.392 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.064 | -0.01101 | 0.8088 | 0.07461 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6570 | 2.177 | 1.496 | 1.396 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.948 | 1.365 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.41012</span> | 101.2 | 0.01728 | 0.2819 | 0.09144 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01717 | 0.4972 | 0.8088 | 0.07461 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6570 | 2.177 | 1.496 | 1.396 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.948 | 1.365 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 17.88 | -0.8521 | 0.09625 | -0.2834 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.006 | 0.008928 | -8.320 | -8.272 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6841 | -8.896 | -4.958 | -5.482 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -7.690 | -4.565 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 51</span>| 475.17343 | 1.006 | -0.9580 | -0.9344 | -0.9592 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9643 | -0.9219 | -0.6806 | -0.6840 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9328 | -0.5062 | -0.7153 | -0.6852 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5694 | -0.7102 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 475.17343 | 100.6 | -4.058 | -0.9354 | -2.392 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.064 | -0.01101 | 0.8127 | 0.07490 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6590 | 2.189 | 1.495 | 1.397 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.955 | 1.368 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 475.17343</span> | 100.6 | 0.01728 | 0.2818 | 0.09146 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01718 | 0.4972 | 0.8127 | 0.07490 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6590 | 2.189 | 1.495 | 1.397 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.955 | 1.368 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -22.54 | -1.885 | -0.4332 | -0.003109 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9120 | 0.01053 | -7.129 | -7.659 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8338 | -8.700 | -4.918 | -5.365 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -7.558 | -4.481 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 52</span>| 474.94312 | 1.012 | -0.9570 | -0.9345 | -0.9591 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9638 | -0.9220 | -0.6676 | -0.6825 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9307 | -0.4984 | -0.7146 | -0.6834 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5639 | -0.7072 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.94312 | 101.2 | -4.057 | -0.9355 | -2.392 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.064 | -0.01101 | 0.8175 | 0.07495 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6604 | 2.202 | 1.496 | 1.399 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.963 | 1.372 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.94312</span> | 101.2 | 0.01730 | 0.2818 | 0.09147 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01718 | 0.4972 | 0.8175 | 0.07495 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6604 | 2.202 | 1.496 | 1.399 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.963 | 1.372 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 20.08 | -0.5236 | 0.1181 | -0.2986 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9599 | 0.008866 | -5.310 | -6.088 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8565 | -8.707 | -4.867 | -5.430 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -7.458 | -4.464 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 53</span>| 474.70657 | 1.007 | -0.9569 | -0.9346 | -0.9588 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9629 | -0.9220 | -0.6640 | -0.6851 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9296 | -0.4868 | -0.7112 | -0.6784 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5553 | -0.7021 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.70657 | 100.7 | -4.057 | -0.9356 | -2.392 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.063 | -0.01101 | 0.8188 | 0.07487 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6612 | 2.220 | 1.500 | 1.405 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.976 | 1.378 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.70657</span> | 100.7 | 0.01730 | 0.2818 | 0.09149 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01720 | 0.4972 | 0.8188 | 0.07487 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6612 | 2.220 | 1.500 | 1.405 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.976 | 1.378 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -17.64 | -1.502 | -0.3627 | -0.03824 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.7798 | 0.01049 | -5.965 | -8.154 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.5631 | -8.385 | -4.675 | -5.151 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -7.306 | -4.317 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 54</span>| 474.46623 | 1.012 | -0.9580 | -0.9346 | -0.9586 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9630 | -0.9221 | -0.6659 | -0.6813 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9264 | -0.4751 | -0.7083 | -0.6739 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5464 | -0.6970 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.46623 | 101.2 | -4.058 | -0.9356 | -2.391 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.063 | -0.01101 | 0.8181 | 0.07499 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6633 | 2.239 | 1.504 | 1.410 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.989 | 1.384 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.46623</span> | 101.2 | 0.01728 | 0.2818 | 0.09151 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01720 | 0.4972 | 0.8181 | 0.07499 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6633 | 2.239 | 1.504 | 1.410 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 1.989 | 1.384 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 15.93 | -0.7754 | 0.09266 | -0.2754 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8835 | 0.009135 | -6.026 | -6.068 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.8217 | -8.210 | -4.532 | -5.141 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -7.011 | -4.237 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 55</span>| 474.23394 | 1.006 | -0.9577 | -0.9351 | -0.9581 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9633 | -0.9221 | -0.6610 | -0.6793 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9234 | -0.4633 | -0.7068 | -0.6694 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5382 | -0.6917 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 474.23394 | 100.6 | -4.058 | -0.9360 | -2.391 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.063 | -0.01101 | 0.8199 | 0.07506 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6654 | 2.257 | 1.506 | 1.415 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.001 | 1.390 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 474.23394</span> | 100.6 | 0.01729 | 0.2817 | 0.09156 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01719 | 0.4972 | 0.8199 | 0.07506 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6654 | 2.257 | 1.506 | 1.415 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.001 | 1.390 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -20.30 | -1.703 | -0.3919 | -0.002629 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8653 | 0.01064 | -4.947 | -7.765 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7818 | -8.010 | -4.437 | -4.875 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -6.938 | -4.094 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 56</span>| 473.98878 | 1.011 | -0.9542 | -0.9354 | -0.9578 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9619 | -0.9222 | -0.6621 | -0.6770 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9235 | -0.4507 | -0.7053 | -0.6648 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5298 | -0.6863 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.98878 | 101.1 | -4.054 | -0.9363 | -2.390 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.062 | -0.01101 | 0.8195 | 0.07514 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6653 | 2.277 | 1.508 | 1.421 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.013 | 1.396 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.98878</span> | 101.1 | 0.01735 | 0.2816 | 0.09159 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01722 | 0.4972 | 0.8195 | 0.07514 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6653 | 2.277 | 1.508 | 1.421 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.013 | 1.396 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 57</span>| 473.76836 | 1.011 | -0.9500 | -0.9359 | -0.9574 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9601 | -0.9223 | -0.6653 | -0.6763 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9234 | -0.4357 | -0.7046 | -0.6601 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5205 | -0.6802 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 473.76836 | 101.1 | -4.050 | -0.9368 | -2.390 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.060 | -0.01101 | 0.8183 | 0.07516 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6654 | 2.301 | 1.509 | 1.426 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.027 | 1.403 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 473.76836</span> | 101.1 | 0.01742 | 0.2815 | 0.09163 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01725 | 0.4972 | 0.8183 | 0.07516 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6654 | 2.301 | 1.509 | 1.426 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.027 | 1.403 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 58</span>| 472.96708 | 1.009 | -0.9317 | -0.9384 | -0.9555 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9527 | -0.9228 | -0.6791 | -0.6735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9230 | -0.3711 | -0.7015 | -0.6396 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4802 | -0.6537 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 472.96708 | 100.9 | -4.032 | -0.9391 | -2.388 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.053 | -0.01101 | 0.8133 | 0.07525 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6656 | 2.403 | 1.513 | 1.450 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.087 | 1.433 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 472.96708</span> | 100.9 | 0.01774 | 0.2811 | 0.09180 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01737 | 0.4972 | 0.8133 | 0.07525 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6656 | 2.403 | 1.513 | 1.450 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.087 | 1.433 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 59</span>| 472.23802 | 1.005 | -0.8811 | -0.9451 | -0.9502 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9323 | -0.9240 | -0.7172 | -0.6658 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9220 | -0.1924 | -0.6930 | -0.5829 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3688 | -0.5805 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 472.23802 | 100.5 | -3.981 | -0.9455 | -2.383 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.032 | -0.01103 | 0.7994 | 0.07551 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6663 | 2.686 | 1.523 | 1.515 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.251 | 1.518 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 472.23802</span> | 100.5 | 0.01866 | 0.2798 | 0.09228 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01773 | 0.4972 | 0.7994 | 0.07551 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6663 | 2.686 | 1.523 | 1.515 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.251 | 1.518 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -10.41 | 25.09 | -1.964 | 0.8913 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.956 | 0.02208 | -7.724 | -8.360 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01123 | -2.619 | -3.185 | -1.886 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -3.376 | -1.727 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 60</span>| 470.34942 | 1.020 | -1.007 | -0.9408 | -0.9496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9429 | -0.9259 | -0.7397 | -0.6282 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9207 | 0.06578 | -0.6693 | -0.4998 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2002 | -0.4722 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 470.34942 | 102.0 | -4.107 | -0.9414 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.043 | -0.01105 | 0.7911 | 0.07677 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6672 | 3.094 | 1.553 | 1.610 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.500 | 1.642 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 470.34942</span> | 102.0 | 0.01646 | 0.2806 | 0.09235 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01755 | 0.4972 | 0.7911 | 0.07677 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6672 | 3.094 | 1.553 | 1.610 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.500 | 1.642 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 49.94 | -17.10 | 1.872 | -1.413 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.684 | 0.005064 | -7.591 | -5.431 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2085 | -2.165 | -1.196 | -0.1732 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4074 | -0.2957 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 61</span>| 480.76065 | 0.9913 | -0.9789 | -0.9482 | -0.9314 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.207 | -0.9279 | -0.6546 | -0.4866 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9168 | 0.2296 | -0.6593 | -0.5083 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1307 | -0.4332 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 480.76065 | 99.13 | -4.079 | -0.9483 | -2.364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.307 | -0.01107 | 0.8222 | 0.08152 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6698 | 3.353 | 1.566 | 1.601 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.603 | 1.687 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 480.76065</span> | 99.13 | 0.01693 | 0.2792 | 0.09404 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01347 | 0.4972 | 0.8222 | 0.08152 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6698 | 3.353 | 1.566 | 1.601 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.603 | 1.687 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 62</span>| 472.12595 | 0.9860 | -0.9933 | -0.9428 | -0.9466 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9755 | -0.9261 | -0.7254 | -0.6089 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9204 | 0.08558 | -0.6674 | -0.5007 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1921 | -0.4676 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 472.12595 | 98.60 | -4.093 | -0.9433 | -2.379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.076 | -0.01105 | 0.7964 | 0.07742 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6674 | 3.125 | 1.556 | 1.609 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.512 | 1.648 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 472.12595</span> | 98.60 | 0.01668 | 0.2802 | 0.09262 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01698 | 0.4972 | 0.7964 | 0.07742 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6674 | 3.125 | 1.556 | 1.609 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.512 | 1.648 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 63</span>| 470.26696 | 1.005 | -1.002 | -0.9414 | -0.9491 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9444 | -0.9259 | -0.7373 | -0.6265 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9207 | 0.06646 | -0.6689 | -0.4998 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2001 | -0.4721 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 470.26696 | 100.5 | -4.102 | -0.9420 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.044 | -0.01105 | 0.7920 | 0.07683 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6672 | 3.095 | 1.554 | 1.610 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.501 | 1.642 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 470.26696</span> | 100.5 | 0.01654 | 0.2805 | 0.09239 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01752 | 0.4972 | 0.7920 | 0.07683 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6672 | 3.095 | 1.554 | 1.610 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.501 | 1.642 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -57.97 | -21.53 | 0.3336 | -0.1964 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 4.949 | 0.01388 | -7.299 | -5.475 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3363 | -1.951 | -1.200 | 0.1716 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4705 | -0.2755 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 64</span>| 469.85165 | 1.014 | -0.9972 | -0.9415 | -0.9489 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9548 | -0.9260 | -0.7307 | -0.6235 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9208 | 0.07069 | -0.6682 | -0.5004 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1987 | -0.4712 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 469.85165 | 101.4 | -4.097 | -0.9421 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.055 | -0.01105 | 0.7944 | 0.07693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6671 | 3.101 | 1.555 | 1.610 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.503 | 1.643 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 469.85165</span> | 101.4 | 0.01662 | 0.2805 | 0.09241 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01734 | 0.4972 | 0.7944 | 0.07693 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6671 | 3.101 | 1.555 | 1.610 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.503 | 1.643 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 9.302 | -15.01 | 1.055 | -0.6015 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.082 | 0.004567 | -8.090 | -5.650 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2579 | -2.336 | -1.339 | -0.08766 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5208 | -0.3062 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 65</span>| 469.69998 | 1.007 | -0.9853 | -0.9423 | -0.9484 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9564 | -0.9260 | -0.7231 | -0.6186 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9204 | 0.07309 | -0.6671 | -0.5006 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1982 | -0.4709 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 469.69998 | 100.7 | -4.085 | -0.9429 | -2.381 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.056 | -0.01105 | 0.7972 | 0.07709 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6674 | 3.105 | 1.556 | 1.610 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.503 | 1.644 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 469.69998</span> | 100.7 | 0.01682 | 0.2803 | 0.09245 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01731 | 0.4972 | 0.7972 | 0.07709 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6674 | 3.105 | 1.556 | 1.610 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.503 | 1.644 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -36.86 | -12.39 | 0.1028 | 0.1354 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7614 | 0.008951 | -8.542 | -6.076 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2246 | -2.313 | -1.235 | 0.1010 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5654 | -0.2998 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 66</span>| 469.45579 | 1.013 | -0.9821 | -0.9425 | -0.9491 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9562 | -0.9260 | -0.7099 | -0.6134 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9182 | 0.07758 | -0.6674 | -0.5042 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1996 | -0.4719 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 469.45579 | 101.3 | -4.082 | -0.9430 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.056 | -0.01105 | 0.8020 | 0.07727 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6689 | 3.112 | 1.556 | 1.605 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.501 | 1.643 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 469.45579</span> | 101.3 | 0.01687 | 0.2803 | 0.09239 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01731 | 0.4972 | 0.8020 | 0.07727 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6689 | 3.112 | 1.556 | 1.605 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.501 | 1.643 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 7.383 | -7.976 | 0.5709 | -0.2773 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.4749 | 0.005686 | -7.013 | -4.742 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3037 | -2.186 | -1.089 | -0.04880 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5661 | -0.3435 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 67</span>| 469.35718 | 1.007 | -0.9760 | -0.9430 | -0.9493 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9561 | -0.9261 | -0.6977 | -0.6075 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9166 | 0.08278 | -0.6675 | -0.5068 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2001 | -0.4722 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 469.35718 | 100.7 | -4.076 | -0.9435 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.056 | -0.01105 | 0.8065 | 0.07747 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6700 | 3.121 | 1.556 | 1.602 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.501 | 1.642 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 469.35718</span> | 100.7 | 0.01698 | 0.2802 | 0.09237 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01732 | 0.4972 | 0.8065 | 0.07747 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6700 | 3.121 | 1.556 | 1.602 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.501 | 1.642 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -28.34 | -7.406 | -0.07810 | 0.1748 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6873 | 0.009156 | -6.696 | -4.901 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2913 | -2.170 | -1.086 | -0.02443 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6503 | -0.3607 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 68</span>| 469.19639 | 1.012 | -0.9749 | -0.9431 | -0.9497 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9576 | -0.9262 | -0.6862 | -0.6021 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9137 | 0.09137 | -0.6688 | -0.5111 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2009 | -0.4726 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 469.19639 | 101.2 | -4.075 | -0.9436 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01105 | 0.8107 | 0.07765 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6719 | 3.134 | 1.554 | 1.597 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.499 | 1.642 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 469.19639</span> | 101.2 | 0.01699 | 0.2802 | 0.09233 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8107 | 0.07765 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6719 | 3.134 | 1.554 | 1.597 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.499 | 1.642 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.760 | -4.629 | 0.3091 | -0.1325 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.04401 | 0.005819 | -5.826 | -2.903 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1562 | -2.130 | -1.121 | -0.2535 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6922 | -0.4141 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 69</span>| 469.12263 | 1.008 | -0.9713 | -0.9434 | -0.9499 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9575 | -0.9262 | -0.6727 | -0.6012 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9123 | 0.09974 | -0.6678 | -0.5134 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2010 | -0.4726 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 469.12263 | 100.8 | -4.071 | -0.9438 | -2.383 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01105 | 0.8156 | 0.07768 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6728 | 3.147 | 1.555 | 1.595 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.499 | 1.642 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 469.12263</span> | 100.8 | 0.01706 | 0.2801 | 0.09232 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8156 | 0.07768 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6728 | 3.147 | 1.555 | 1.595 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.499 | 1.642 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -20.86 | -4.532 | -0.1251 | 0.1663 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1284 | 0.008177 | -5.101 | -3.487 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2183 | -2.137 | -1.171 | -0.2991 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6817 | -0.4261 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 70</span>| 469.02483 | 1.011 | -0.9711 | -0.9434 | -0.9500 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9569 | -0.9263 | -0.6616 | -0.6038 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9105 | 0.1111 | -0.6656 | -0.5157 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2026 | -0.4730 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 469.02483 | 101.1 | -4.071 | -0.9439 | -2.383 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01105 | 0.8196 | 0.07759 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6741 | 3.165 | 1.558 | 1.592 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.497 | 1.641 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 469.02483</span> | 101.1 | 0.01706 | 0.2801 | 0.09230 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8196 | 0.07759 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6741 | 3.165 | 1.558 | 1.592 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.497 | 1.641 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.786 | -2.589 | 0.2046 | -0.1061 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1383 | 0.006373 | -4.080 | -2.588 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1418 | -1.956 | -0.9118 | -0.4226 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7530 | -0.4429 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 71</span>| 468.97618 | 1.009 | -0.9710 | -0.9439 | -0.9494 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9625 | -0.9265 | -0.6573 | -0.5998 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9085 | 0.1255 | -0.6648 | -0.5157 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2015 | -0.4719 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.97618 | 100.9 | -4.071 | -0.9443 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.063 | -0.01106 | 0.8212 | 0.07773 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6755 | 3.188 | 1.559 | 1.592 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.498 | 1.643 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.97618</span> | 100.9 | 0.01706 | 0.2800 | 0.09236 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01721 | 0.4972 | 0.8212 | 0.07773 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6755 | 3.188 | 1.559 | 1.592 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.498 | 1.643 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -11.25 | -3.431 | -0.02518 | 0.1501 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -1.529 | 0.005347 | -4.655 | -3.448 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3102 | -2.013 | -0.8937 | -0.3742 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7403 | -0.4511 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 72</span>| 468.91299 | 1.010 | -0.9702 | -0.9444 | -0.9496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9534 | -0.9266 | -0.6524 | -0.5929 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9051 | 0.1362 | -0.6665 | -0.5172 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2029 | -0.4725 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.91299 | 101.0 | -4.070 | -0.9448 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.053 | -0.01106 | 0.8230 | 0.07796 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6777 | 3.205 | 1.557 | 1.590 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.496 | 1.642 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.91299</span> | 101.0 | 0.01707 | 0.2799 | 0.09234 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01736 | 0.4972 | 0.8230 | 0.07796 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6777 | 3.205 | 1.557 | 1.590 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.496 | 1.642 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -8.129 | -2.859 | -0.02802 | -0.004107 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 1.281 | 0.009120 | -4.291 | -2.058 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1551 | -2.052 | -1.121 | -0.5699 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7547 | -0.4743 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 73</span>| 471.25018 | 1.036 | -0.9607 | -0.9443 | -0.9496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9576 | -0.9266 | -0.6382 | -0.5860 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9046 | 0.1430 | -0.6628 | -0.5153 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2004 | -0.4709 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 471.25018 | 103.6 | -4.061 | -0.9447 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01106 | 0.8282 | 0.07819 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6781 | 3.216 | 1.562 | 1.593 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.500 | 1.644 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 471.25018</span> | 103.6 | 0.01724 | 0.2800 | 0.09234 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8282 | 0.07819 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6781 | 3.216 | 1.562 | 1.593 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.500 | 1.644 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 74</span>| 468.90555 | 1.012 | -0.9692 | -0.9444 | -0.9496 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9538 | -0.9266 | -0.6510 | -0.5922 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9050 | 0.1369 | -0.6661 | -0.5170 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2027 | -0.4723 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.90555 | 101.2 | -4.069 | -0.9448 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.054 | -0.01106 | 0.8235 | 0.07798 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6778 | 3.206 | 1.557 | 1.591 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.497 | 1.642 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.90555</span> | 101.2 | 0.01709 | 0.2799 | 0.09234 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01736 | 0.4972 | 0.8235 | 0.07798 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6778 | 3.206 | 1.557 | 1.591 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.497 | 1.642 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 11.48 | -1.027 | 0.1960 | -0.1655 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9827 | 0.007474 | -3.960 | -2.226 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2199 | -2.046 | -1.158 | -0.6171 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7493 | -0.4797 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 75</span>| 468.88608 | 1.010 | -0.9691 | -0.9444 | -0.9495 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9542 | -0.9266 | -0.6497 | -0.5917 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9044 | 0.1391 | -0.6659 | -0.5166 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2026 | -0.4722 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.88608 | 101.0 | -4.069 | -0.9448 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.054 | -0.01106 | 0.8240 | 0.07799 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6782 | 3.210 | 1.558 | 1.591 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.497 | 1.642 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.88608</span> | 101.0 | 0.01709 | 0.2799 | 0.09235 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01735 | 0.4972 | 0.8240 | 0.07799 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6782 | 3.210 | 1.558 | 1.591 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.497 | 1.642 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.784 | -1.944 | 0.009889 | -0.02065 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.9781 | 0.008521 | -3.685 | -1.489 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.08345 | -1.963 | -0.9408 | -0.4978 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7271 | -0.4658 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 76</span>| 468.87604 | 1.012 | -0.9680 | -0.9444 | -0.9495 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9547 | -0.9266 | -0.6476 | -0.5909 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9043 | 0.1402 | -0.6654 | -0.5163 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2021 | -0.4719 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.87604 | 101.2 | -4.068 | -0.9448 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.055 | -0.01106 | 0.8248 | 0.07802 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6783 | 3.211 | 1.558 | 1.591 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.498 | 1.643 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.87604</span> | 101.2 | 0.01711 | 0.2799 | 0.09235 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01734 | 0.4972 | 0.8248 | 0.07802 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6783 | 3.211 | 1.558 | 1.591 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.498 | 1.643 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 9.309 | -0.5261 | 0.1314 | -0.1053 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6891 | 0.007435 | -3.809 | -2.129 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2297 | -2.013 | -1.108 | -0.5855 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7533 | -0.4780 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 77</span>| 468.85962 | 1.010 | -0.9680 | -0.9444 | -0.9495 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9550 | -0.9266 | -0.6462 | -0.5907 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9037 | 0.1428 | -0.6653 | -0.5160 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2020 | -0.4717 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.85962 | 101.0 | -4.068 | -0.9448 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.055 | -0.01106 | 0.8253 | 0.07803 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6787 | 3.215 | 1.558 | 1.592 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.498 | 1.643 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.85962</span> | 101.0 | 0.01711 | 0.2799 | 0.09235 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01734 | 0.4972 | 0.8253 | 0.07803 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6787 | 3.215 | 1.558 | 1.592 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.498 | 1.643 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.556 | -1.258 | -0.007590 | 0.001179 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7035 | 0.008243 | -4.446 | -2.277 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2406 | -1.984 | -1.075 | -0.5476 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7588 | -0.4741 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 78</span>| 468.84535 | 1.011 | -0.9673 | -0.9444 | -0.9495 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9554 | -0.9266 | -0.6436 | -0.5895 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9036 | 0.1439 | -0.6647 | -0.5157 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2016 | -0.4714 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.84535 | 101.1 | -4.067 | -0.9448 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.055 | -0.01106 | 0.8262 | 0.07807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6788 | 3.217 | 1.559 | 1.592 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.498 | 1.643 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.84535</span> | 101.1 | 0.01712 | 0.2799 | 0.09235 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01733 | 0.4972 | 0.8262 | 0.07807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6788 | 3.217 | 1.559 | 1.592 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.498 | 1.643 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.130 | -0.4165 | 0.05789 | -0.04298 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.5152 | 0.007618 | -4.342 | -2.024 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2412 | -1.936 | -0.8986 | -0.4874 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7551 | -0.4761 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 79</span>| 468.83559 | 1.009 | -0.9672 | -0.9445 | -0.9494 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9556 | -0.9266 | -0.6414 | -0.5890 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9032 | 0.1455 | -0.6647 | -0.5153 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2012 | -0.4711 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.83559 | 100.9 | -4.067 | -0.9449 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.056 | -0.01106 | 0.8270 | 0.07809 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6790 | 3.220 | 1.559 | 1.593 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.499 | 1.643 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.83559</span> | 100.9 | 0.01713 | 0.2799 | 0.09236 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01733 | 0.4972 | 0.8270 | 0.07809 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6790 | 3.220 | 1.559 | 1.593 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.499 | 1.643 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -7.676 | -1.212 | -0.1115 | 0.08612 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.5488 | 0.008589 | -2.761 | -2.165 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2456 | -1.924 | -0.8622 | -0.4413 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7592 | -0.4720 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 80</span>| 468.82320 | 1.011 | -0.9670 | -0.9445 | -0.9494 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9559 | -0.9267 | -0.6401 | -0.5885 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9025 | 0.1478 | -0.6651 | -0.5152 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2008 | -0.4708 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.8232 | 101.1 | -4.067 | -0.9449 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.056 | -0.01106 | 0.8275 | 0.07810 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6795 | 3.223 | 1.559 | 1.593 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.499 | 1.644 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.8232</span> | 101.1 | 0.01713 | 0.2799 | 0.09236 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01732 | 0.4972 | 0.8275 | 0.07810 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6795 | 3.223 | 1.559 | 1.593 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.499 | 1.644 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.440 | -0.1810 | 0.05193 | -0.03082 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3483 | 0.007438 | -3.541 | -1.923 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2409 | -1.947 | -1.058 | -0.5469 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7518 | -0.4735 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 81</span>| 468.81154 | 1.010 | -0.9671 | -0.9445 | -0.9493 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9562 | -0.9267 | -0.6389 | -0.5880 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9017 | 0.1505 | -0.6652 | -0.5150 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2005 | -0.4704 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.81154 | 101.0 | -4.067 | -0.9449 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.056 | -0.01106 | 0.8279 | 0.07812 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6800 | 3.228 | 1.559 | 1.593 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.500 | 1.644 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.81154</span> | 101.0 | 0.01713 | 0.2799 | 0.09237 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01732 | 0.4972 | 0.8279 | 0.07812 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6800 | 3.228 | 1.559 | 1.593 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.500 | 1.644 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.875 | -0.7736 | -0.05343 | 0.05244 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.3113 | 0.007978 | -4.161 | -2.012 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2433 | -1.896 | -0.8853 | -0.4539 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7524 | -0.4694 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 82</span>| 468.80001 | 1.011 | -0.9668 | -0.9445 | -0.9493 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9563 | -0.9267 | -0.6364 | -0.5873 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9013 | 0.1522 | -0.6651 | -0.5147 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2001 | -0.4701 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.80001 | 101.1 | -4.067 | -0.9449 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.056 | -0.01106 | 0.8288 | 0.07814 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6803 | 3.230 | 1.559 | 1.593 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.501 | 1.645 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.80001</span> | 101.1 | 0.01713 | 0.2799 | 0.09237 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01731 | 0.4972 | 0.8288 | 0.07814 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6803 | 3.230 | 1.559 | 1.593 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.501 | 1.645 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 6.046 | 0.03721 | 0.05257 | -0.02595 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1943 | 0.007238 | -2.985 | -2.233 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3122 | -1.891 | -0.9609 | -0.5652 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.8019 | -0.4712 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 83</span>| 468.79133 | 1.009 | -0.9669 | -0.9445 | -0.9492 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9565 | -0.9267 | -0.6348 | -0.5869 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9006 | 0.1543 | -0.6654 | -0.5144 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1996 | -0.4698 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.79133 | 100.9 | -4.067 | -0.9449 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.056 | -0.01106 | 0.8294 | 0.07816 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6807 | 3.234 | 1.558 | 1.594 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.501 | 1.645 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.79133</span> | 100.9 | 0.01713 | 0.2799 | 0.09237 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01731 | 0.4972 | 0.8294 | 0.07816 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6807 | 3.234 | 1.558 | 1.594 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.501 | 1.645 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -7.226 | -0.9038 | -0.1166 | 0.1039 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2475 | 0.008246 | -3.388 | -1.948 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2420 | -1.872 | -0.8620 | -0.4291 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7186 | -0.4561 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 84</span>| 468.77848 | 1.011 | -0.9668 | -0.9446 | -0.9492 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9568 | -0.9267 | -0.6338 | -0.5863 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8997 | 0.1569 | -0.6658 | -0.5142 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1992 | -0.4695 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.77848 | 101.1 | -4.067 | -0.9450 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01106 | 0.8298 | 0.07818 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6814 | 3.238 | 1.558 | 1.594 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.502 | 1.645 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.77848</span> | 101.1 | 0.01713 | 0.2799 | 0.09238 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8298 | 0.07818 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6814 | 3.238 | 1.558 | 1.594 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.502 | 1.645 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.503 | -0.1762 | 0.005994 | 0.01651 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.06327 | 0.007339 | -4.407 | -2.185 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3133 | -1.836 | -0.8110 | -0.4803 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7946 | -0.4665 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 85</span>| 468.76805 | 1.010 | -0.9668 | -0.9446 | -0.9492 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9569 | -0.9267 | -0.6312 | -0.5853 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8993 | 0.1583 | -0.6657 | -0.5139 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1987 | -0.4691 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.76805 | 101.0 | -4.067 | -0.9450 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01106 | 0.8307 | 0.07821 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6816 | 3.240 | 1.558 | 1.594 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.503 | 1.646 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.76805</span> | 101.0 | 0.01713 | 0.2799 | 0.09238 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8307 | 0.07821 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6816 | 3.240 | 1.558 | 1.594 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.503 | 1.646 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.980 | -0.7098 | -0.1045 | 0.1001 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.1097 | 0.008007 | -2.998 | -1.799 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2421 | -1.902 | -1.021 | -0.4929 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7234 | -0.4545 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 86</span>| 468.76178 | 1.012 | -0.9666 | -0.9446 | -0.9492 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9569 | -0.9268 | -0.6296 | -0.5849 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8987 | 0.1602 | -0.6657 | -0.5136 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1982 | -0.4689 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.76178 | 101.2 | -4.067 | -0.9450 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01106 | 0.8313 | 0.07822 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6820 | 3.243 | 1.558 | 1.595 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.503 | 1.646 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.76178</span> | 101.2 | 0.01714 | 0.2799 | 0.09238 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8313 | 0.07822 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6820 | 3.243 | 1.558 | 1.595 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.503 | 1.646 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 9.381 | 0.4945 | 0.08709 | -0.04347 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.04178 | 0.006758 | -3.785 | -1.947 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3007 | -1.819 | -0.8940 | -0.4901 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7836 | -0.4662 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 87</span>| 468.74724 | 1.010 | -0.9668 | -0.9447 | -0.9491 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9570 | -0.9268 | -0.6284 | -0.5849 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8978 | 0.1628 | -0.6658 | -0.5134 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1979 | -0.4686 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.74724 | 101.0 | -4.067 | -0.9451 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01106 | 0.8318 | 0.07822 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6827 | 3.247 | 1.558 | 1.595 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.504 | 1.646 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.74724</span> | 101.0 | 0.01713 | 0.2799 | 0.09239 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8318 | 0.07822 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6827 | 3.247 | 1.558 | 1.595 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.504 | 1.646 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.251 | -0.3146 | -0.04610 | 0.05724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.02086 | 0.007590 | -4.230 | -2.098 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3136 | -1.833 | -0.9365 | -0.5244 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7857 | -0.4618 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 88</span>| 468.73570 | 1.011 | -0.9666 | -0.9446 | -0.9492 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9570 | -0.9268 | -0.6257 | -0.5836 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8976 | 0.1639 | -0.6652 | -0.5131 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1974 | -0.4683 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.7357 | 101.1 | -4.067 | -0.9450 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01106 | 0.8327 | 0.07827 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6828 | 3.249 | 1.559 | 1.595 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.504 | 1.647 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.7357</span> | 101.1 | 0.01714 | 0.2799 | 0.09238 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8327 | 0.07827 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6828 | 3.249 | 1.559 | 1.595 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.504 | 1.647 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 4.473 | 0.2106 | 0.02342 | 0.003517 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.03354 | 0.007130 | -3.431 | -1.904 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3114 | -1.829 | -0.9161 | -0.5352 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7806 | -0.4641 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 89</span>| 468.73562 | 1.009 | -0.9667 | -0.9447 | -0.9491 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9570 | -0.9268 | -0.6239 | -0.5826 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8973 | 0.1651 | -0.6648 | -0.5128 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1970 | -0.4681 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.73562 | 100.9 | -4.067 | -0.9450 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01106 | 0.8334 | 0.07830 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6830 | 3.251 | 1.559 | 1.596 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.505 | 1.647 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.73562</span> | 100.9 | 0.01713 | 0.2799 | 0.09238 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8334 | 0.07830 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6830 | 3.251 | 1.559 | 1.596 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.505 | 1.647 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | C| Central Diff. | -12.26 | -1.176 | -0.2138 | 0.1217 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.02157 | 0.008077 | -2.776 | -1.301 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1367 | -1.738 | -0.7465 | -0.4531 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7359 | -0.4611 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 90</span>| 468.72331 | 1.010 | -0.9665 | -0.9446 | -0.9492 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9570 | -0.9268 | -0.6235 | -0.5825 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8973 | 0.1654 | -0.6647 | -0.5127 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1969 | -0.4680 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.72331 | 101.0 | -4.067 | -0.9450 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01106 | 0.8335 | 0.07831 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6830 | 3.251 | 1.559 | 1.596 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.505 | 1.647 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.72331</span> | 101.0 | 0.01714 | 0.2799 | 0.09238 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8335 | 0.07831 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6830 | 3.251 | 1.559 | 1.596 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.505 | 1.647 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.3583 | -0.08989 | -0.03828 | 0.04946 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.006154 | 0.007526 | -3.405 | -1.898 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3214 | -1.836 | -0.8751 | -0.5118 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7778 | -0.4622 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 91</span>| 468.71715 | 1.011 | -0.9665 | -0.9446 | -0.9492 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9570 | -0.9268 | -0.6223 | -0.5817 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8972 | 0.1661 | -0.6643 | -0.5125 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1966 | -0.4678 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.71715 | 101.1 | -4.067 | -0.9450 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01106 | 0.8340 | 0.07833 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6831 | 3.252 | 1.560 | 1.596 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.506 | 1.647 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.71715</span> | 101.1 | 0.01714 | 0.2799 | 0.09238 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8340 | 0.07833 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6831 | 3.252 | 1.560 | 1.596 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.506 | 1.647 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 92</span>| 468.70862 | 1.011 | -0.9665 | -0.9446 | -0.9492 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9570 | -0.9268 | -0.6204 | -0.5807 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8970 | 0.1671 | -0.6639 | -0.5123 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1962 | -0.4676 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.70862 | 101.1 | -4.066 | -0.9450 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01106 | 0.8347 | 0.07836 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6832 | 3.254 | 1.560 | 1.596 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.506 | 1.648 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.70862</span> | 101.1 | 0.01714 | 0.2799 | 0.09238 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8347 | 0.07836 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6832 | 3.254 | 1.560 | 1.596 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.506 | 1.648 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 93</span>| 468.69301 | 1.011 | -0.9664 | -0.9446 | -0.9493 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9570 | -0.9268 | -0.6166 | -0.5786 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8967 | 0.1691 | -0.6629 | -0.5117 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1953 | -0.4671 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.69301 | 101.1 | -4.066 | -0.9449 | -2.382 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01106 | 0.8361 | 0.07843 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6834 | 3.257 | 1.562 | 1.597 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.508 | 1.648 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.69301</span> | 101.1 | 0.01714 | 0.2799 | 0.09237 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8361 | 0.07843 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6834 | 3.257 | 1.562 | 1.597 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.508 | 1.648 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.000 | 0.4463 | 0.03173 | -0.005614 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.04729 | 0.007073 | -3.041 | -1.513 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3269 | -1.766 | -0.6347 | -0.4208 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.7611 | -0.4631 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 94</span>| 468.66018 | 1.011 | -0.9666 | -0.9442 | -0.9484 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9562 | -0.9269 | -0.6101 | -0.5828 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8947 | 0.1828 | -0.6704 | -0.5138 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1918 | -0.4639 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.66018 | 101.1 | -4.067 | -0.9446 | -2.381 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.056 | -0.01106 | 0.8385 | 0.07829 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6847 | 3.279 | 1.552 | 1.594 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.513 | 1.652 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.66018</span> | 101.1 | 0.01714 | 0.2800 | 0.09245 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01731 | 0.4972 | 0.8385 | 0.07829 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6847 | 3.279 | 1.552 | 1.594 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.513 | 1.652 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 95</span>| 468.61872 | 1.011 | -0.9669 | -0.9434 | -0.9467 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9547 | -0.9271 | -0.5984 | -0.5914 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8911 | 0.2086 | -0.6849 | -0.5181 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1852 | -0.4581 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.61872 | 101.1 | -4.067 | -0.9439 | -2.379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.055 | -0.01106 | 0.8427 | 0.07801 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6872 | 3.320 | 1.534 | 1.589 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.523 | 1.658 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.61872</span> | 101.1 | 0.01713 | 0.2801 | 0.09261 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01734 | 0.4972 | 0.8427 | 0.07801 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6872 | 3.320 | 1.534 | 1.589 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.523 | 1.658 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.484 | 0.5384 | 0.08463 | 0.09865 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7055 | 0.007848 | -2.909 | -1.559 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2162 | -1.642 | -1.728 | -0.7121 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5947 | -0.3648 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 96</span>| 468.58548 | 1.008 | -0.9690 | -0.9515 | -0.9524 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9418 | -0.9281 | -0.5713 | -0.6320 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8823 | 0.2961 | -0.6589 | -0.5284 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1884 | -0.4503 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.58548 | 100.8 | -4.069 | -0.9515 | -2.385 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.042 | -0.01107 | 0.8526 | 0.07665 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6931 | 3.458 | 1.567 | 1.578 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.518 | 1.667 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.58548</span> | 100.8 | 0.01709 | 0.2786 | 0.09208 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01757 | 0.4972 | 0.8526 | 0.07665 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6931 | 3.458 | 1.567 | 1.578 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.518 | 1.667 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -20.63 | -1.258 | -0.4941 | -0.2790 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 5.133 | 0.01399 | -2.360 | -3.936 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.04374 | -1.146 | -0.2901 | -1.004 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6864 | -0.2503 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 97</span>| 468.42330 | 1.011 | -0.9777 | -0.9596 | -0.9476 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9583 | -0.9295 | -0.5827 | -0.6211 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8760 | 0.3979 | -0.6632 | -0.5247 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1834 | -0.4404 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.4233 | 101.1 | -4.078 | -0.9591 | -2.380 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01109 | 0.8485 | 0.07701 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6974 | 3.619 | 1.561 | 1.582 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.525 | 1.679 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.4233</span> | 101.1 | 0.01695 | 0.2771 | 0.09253 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01728 | 0.4972 | 0.8485 | 0.07701 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6974 | 3.619 | 1.561 | 1.582 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.525 | 1.679 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.203 | -3.445 | -0.3661 | -0.1876 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3413 | 0.004713 | -2.617 | -2.520 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.09908 | -0.8887 | -0.1336 | -0.9981 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6593 | -0.1712 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 98</span>| 468.44544 | 1.015 | -0.9711 | -0.9083 | -0.9392 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9571 | -0.9308 | -0.5728 | -0.6140 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9111 | 0.4459 | -0.6774 | -0.4582 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1728 | -0.4486 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.44544 | 101.5 | -4.071 | -0.9109 | -2.372 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01110 | 0.8520 | 0.07725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6737 | 3.695 | 1.543 | 1.658 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.541 | 1.669 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.44544</span> | 101.5 | 0.01706 | 0.2868 | 0.09331 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8520 | 0.07725 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6737 | 3.695 | 1.543 | 1.658 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.541 | 1.669 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 99</span>| 468.45245 | 1.016 | -0.9696 | -0.9377 | -0.9438 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9573 | -0.9300 | -0.5745 | -0.6143 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8908 | 0.4193 | -0.6689 | -0.4955 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1780 | -0.4435 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.45245 | 101.6 | -4.070 | -0.9385 | -2.376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01109 | 0.8514 | 0.07724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6874 | 3.653 | 1.554 | 1.615 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.533 | 1.675 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.45245</span> | 101.6 | 0.01708 | 0.2812 | 0.09288 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8514 | 0.07724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6874 | 3.653 | 1.554 | 1.615 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.533 | 1.675 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 100</span>| 468.50368 | 1.017 | -0.9688 | -0.9537 | -0.9463 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9573 | -0.9296 | -0.5755 | -0.6144 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8797 | 0.4047 | -0.6643 | -0.5158 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1808 | -0.4408 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.50368 | 101.7 | -4.069 | -0.9536 | -2.379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01109 | 0.8511 | 0.07724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6949 | 3.630 | 1.560 | 1.592 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.529 | 1.678 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.50368</span> | 101.7 | 0.01710 | 0.2782 | 0.09265 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8511 | 0.07724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6949 | 3.630 | 1.560 | 1.592 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.529 | 1.678 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 101</span>| 468.41664 | 1.014 | -0.9744 | -0.9593 | -0.9474 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9580 | -0.9295 | -0.5802 | -0.6187 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8761 | 0.3987 | -0.6631 | -0.5237 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1828 | -0.4402 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.41664 | 101.4 | -4.074 | -0.9588 | -2.380 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01109 | 0.8494 | 0.07709 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6973 | 3.620 | 1.561 | 1.583 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.526 | 1.679 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.41664</span> | 101.4 | 0.01700 | 0.2771 | 0.09254 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01728 | 0.4972 | 0.8494 | 0.07709 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6973 | 3.620 | 1.561 | 1.583 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.526 | 1.679 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 15.72 | -0.02243 | -0.2559 | -0.2642 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4515 | 0.003975 | -3.178 | -2.839 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.02889 | -0.8526 | -0.3239 | -1.069 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6251 | -0.1666 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 102</span>| 468.39161 | 1.011 | -0.9744 | -0.9571 | -0.9468 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9580 | -0.9295 | -0.5795 | -0.6181 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8777 | 0.4014 | -0.6637 | -0.5208 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1824 | -0.4404 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.39161 | 101.1 | -4.074 | -0.9567 | -2.380 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01109 | 0.8496 | 0.07711 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6962 | 3.624 | 1.561 | 1.586 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.527 | 1.679 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.39161</span> | 101.1 | 0.01700 | 0.2775 | 0.09260 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01728 | 0.4972 | 0.8496 | 0.07711 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6962 | 3.624 | 1.561 | 1.586 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.527 | 1.679 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.3129 | -1.347 | -0.3359 | -0.08922 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3284 | 0.005471 | -2.643 | -3.028 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.08821 | -0.8778 | -0.3083 | -0.9349 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6501 | -0.1781 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 103</span>| 468.37315 | 1.012 | -0.9728 | -0.9567 | -0.9467 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9576 | -0.9295 | -0.5763 | -0.6144 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8776 | 0.4024 | -0.6633 | -0.5197 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1816 | -0.4402 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.37315 | 101.2 | -4.073 | -0.9564 | -2.379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01109 | 0.8508 | 0.07724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6963 | 3.626 | 1.561 | 1.588 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.528 | 1.679 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.37315</span> | 101.2 | 0.01703 | 0.2776 | 0.09261 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8508 | 0.07724 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6963 | 3.626 | 1.561 | 1.588 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.528 | 1.679 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.643 | -0.05906 | -0.3284 | -0.08464 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2659 | 0.005628 | -2.441 | -2.741 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1033 | -0.8597 | -0.2783 | -0.9091 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.6423 | -0.1835 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 104</span>| 468.35774 | 1.011 | -0.9727 | -0.9524 | -0.9471 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9577 | -0.9297 | -0.5762 | -0.6128 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8791 | 0.4096 | -0.6644 | -0.5136 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1797 | -0.4410 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.35774 | 101.1 | -4.073 | -0.9523 | -2.380 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01109 | 0.8508 | 0.07729 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6953 | 3.637 | 1.560 | 1.595 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.531 | 1.678 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.35774</span> | 101.1 | 0.01703 | 0.2784 | 0.09257 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8508 | 0.07729 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6953 | 3.637 | 1.560 | 1.595 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.531 | 1.678 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -4.235 | -0.7549 | -0.2072 | -0.03117 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2512 | 0.006470 | -2.488 | -2.805 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1485 | -0.7903 | -0.1532 | -0.6368 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5813 | -0.1871 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 105</span>| 468.34230 | 1.012 | -0.9728 | -0.9537 | -0.9473 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9580 | -0.9300 | -0.5748 | -0.6111 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8817 | 0.4177 | -0.6661 | -0.5086 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1765 | -0.4413 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.3423 | 101.2 | -4.073 | -0.9535 | -2.380 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01109 | 0.8513 | 0.07735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6935 | 3.650 | 1.558 | 1.600 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.535 | 1.678 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.3423</span> | 101.2 | 0.01703 | 0.2782 | 0.09256 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01728 | 0.4972 | 0.8513 | 0.07735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6935 | 3.650 | 1.558 | 1.600 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.535 | 1.678 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 5.528 | 0.1613 | -0.1518 | -0.1427 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4211 | 0.005662 | -2.339 | -2.549 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1833 | -0.8387 | -0.3838 | -0.5791 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5586 | -0.2081 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 106</span>| 468.32828 | 1.011 | -0.9730 | -0.9582 | -0.9446 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9579 | -0.9303 | -0.5739 | -0.6081 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8827 | 0.4247 | -0.6653 | -0.5110 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1721 | -0.4394 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.32828 | 101.1 | -4.073 | -0.9578 | -2.377 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01110 | 0.8517 | 0.07745 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6929 | 3.661 | 1.559 | 1.598 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.542 | 1.680 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.32828</span> | 101.1 | 0.01703 | 0.2773 | 0.09281 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8517 | 0.07745 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6929 | 3.661 | 1.559 | 1.598 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.542 | 1.680 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.625 | -0.2716 | -0.4478 | 0.07059 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3746 | 0.006164 | -2.097 | -1.611 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.05708 | -0.8042 | -0.2658 | -0.6338 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.5023 | -0.1867 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 107</span>| 468.31633 | 1.012 | -0.9727 | -0.9524 | -0.9447 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9580 | -0.9305 | -0.5707 | -0.6067 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8839 | 0.4327 | -0.6650 | -0.5105 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1703 | -0.4382 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.31633 | 101.2 | -4.073 | -0.9523 | -2.377 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01110 | 0.8528 | 0.07749 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6921 | 3.674 | 1.559 | 1.598 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.545 | 1.681 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.31633</span> | 101.2 | 0.01703 | 0.2784 | 0.09280 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01728 | 0.4972 | 0.8528 | 0.07749 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6921 | 3.674 | 1.559 | 1.598 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.545 | 1.681 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 8.853 | 0.6395 | -0.04718 | -0.01095 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5142 | 0.005281 | -1.984 | -1.469 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.06825 | -0.7616 | -0.1275 | -0.5767 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4529 | -0.1729 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 108</span>| 468.30195 | 1.011 | -0.9730 | -0.9497 | -0.9482 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9586 | -0.9308 | -0.5675 | -0.6075 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8868 | 0.4402 | -0.6670 | -0.5066 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1704 | -0.4381 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.30195 | 101.1 | -4.073 | -0.9498 | -2.381 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.059 | -0.01110 | 0.8540 | 0.07747 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6901 | 3.686 | 1.556 | 1.603 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.544 | 1.681 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.30195</span> | 101.1 | 0.01703 | 0.2789 | 0.09247 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01727 | 0.4972 | 0.8540 | 0.07747 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6901 | 3.686 | 1.556 | 1.603 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.544 | 1.681 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.407 | -0.4624 | -0.02880 | -0.1214 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5499 | 0.005628 | -1.325 | -1.518 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1161 | -0.7707 | -0.3300 | -0.4912 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4772 | -0.1931 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 109</span>| 468.29210 | 1.012 | -0.9733 | -0.9523 | -0.9459 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9581 | -0.9311 | -0.5658 | -0.6073 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8878 | 0.4488 | -0.6682 | -0.5015 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1697 | -0.4385 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.2921 | 101.2 | -4.073 | -0.9523 | -2.379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01111 | 0.8546 | 0.07747 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6894 | 3.699 | 1.555 | 1.608 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.546 | 1.681 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.2921</span> | 101.2 | 0.01702 | 0.2784 | 0.09269 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01728 | 0.4972 | 0.8546 | 0.07747 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6894 | 3.699 | 1.555 | 1.608 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.546 | 1.681 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 110</span>| 468.28540 | 1.012 | -0.9739 | -0.9554 | -0.9432 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9581 | -0.9314 | -0.5648 | -0.6081 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8889 | 0.4579 | -0.6697 | -0.4962 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1692 | -0.4390 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.2854 | 101.2 | -4.074 | -0.9551 | -2.376 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01111 | 0.8550 | 0.07745 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6886 | 3.714 | 1.553 | 1.615 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.546 | 1.680 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.2854</span> | 101.2 | 0.01701 | 0.2779 | 0.09293 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01728 | 0.4972 | 0.8550 | 0.07745 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6886 | 3.714 | 1.553 | 1.615 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.546 | 1.680 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 3.644 | 0.03668 | -0.1986 | 0.05251 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5265 | 0.006364 | -2.013 | -2.999 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3077 | -0.7577 | -0.4283 | -0.2217 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.4457 | -0.1968 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 111</span>| 468.26285 | 1.012 | -0.9738 | -0.9546 | -0.9455 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9580 | -0.9321 | -0.5638 | -0.6053 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8894 | 0.4796 | -0.6701 | -0.4937 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1665 | -0.4375 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.26285 | 101.2 | -4.074 | -0.9544 | -2.378 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01112 | 0.8554 | 0.07754 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6883 | 3.748 | 1.552 | 1.617 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.550 | 1.682 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.26285</span> | 101.2 | 0.01701 | 0.2780 | 0.09272 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01728 | 0.4972 | 0.8554 | 0.07754 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6883 | 3.748 | 1.552 | 1.617 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.550 | 1.682 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 112</span>| 468.24808 | 1.012 | -0.9737 | -0.9538 | -0.9478 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9581 | -0.9328 | -0.5632 | -0.6032 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8900 | 0.5018 | -0.6707 | -0.4913 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1639 | -0.4361 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.24808 | 101.2 | -4.074 | -0.9537 | -2.380 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01113 | 0.8556 | 0.07761 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6879 | 3.783 | 1.552 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.554 | 1.684 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.24808</span> | 101.2 | 0.01701 | 0.2781 | 0.09251 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01728 | 0.4972 | 0.8556 | 0.07761 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6879 | 3.783 | 1.552 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.554 | 1.684 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 7.572 | 0.7442 | -0.1004 | -0.2485 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5511 | 0.005645 | -1.896 | -1.976 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3421 | -0.6164 | -0.3384 | -0.1002 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3637 | -0.1858 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 113</span>| 468.24925 | 1.009 | -0.9744 | -0.9459 | -0.9275 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9570 | -0.9342 | -0.5606 | -0.6003 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8814 | 0.5390 | -0.6664 | -0.4916 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1575 | -0.4319 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.24925 | 100.9 | -4.074 | -0.9463 | -2.360 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01114 | 0.8565 | 0.07771 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6937 | 3.842 | 1.557 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.563 | 1.689 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.24925</span> | 100.9 | 0.01700 | 0.2796 | 0.09441 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8565 | 0.07771 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6937 | 3.842 | 1.557 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.563 | 1.689 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 114</span>| 468.25666 | 1.009 | -0.9742 | -0.9500 | -0.9379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9574 | -0.9335 | -0.5615 | -0.6013 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8858 | 0.5198 | -0.6685 | -0.4914 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1608 | -0.4340 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.25666 | 100.9 | -4.074 | -0.9501 | -2.371 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01113 | 0.8562 | 0.07768 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6908 | 3.812 | 1.554 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.559 | 1.686 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.25666</span> | 100.9 | 0.01701 | 0.2789 | 0.09342 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8562 | 0.07768 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6908 | 3.812 | 1.554 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.559 | 1.686 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 115</span>| 468.26483 | 1.009 | -0.9741 | -0.9524 | -0.9439 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9577 | -0.9331 | -0.5620 | -0.6018 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8883 | 0.5089 | -0.6697 | -0.4913 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1626 | -0.4352 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.26483 | 100.9 | -4.074 | -0.9523 | -2.377 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01113 | 0.8560 | 0.07766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6891 | 3.794 | 1.553 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.556 | 1.685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.26483</span> | 100.9 | 0.01701 | 0.2784 | 0.09287 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8560 | 0.07766 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6891 | 3.794 | 1.553 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.556 | 1.685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 116</span>| 468.25961 | 1.009 | -0.9740 | -0.9538 | -0.9477 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9579 | -0.9328 | -0.5624 | -0.6023 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8898 | 0.5020 | -0.6705 | -0.4913 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1637 | -0.4360 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.25961 | 100.9 | -4.074 | -0.9536 | -2.380 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01113 | 0.8558 | 0.07764 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6880 | 3.783 | 1.552 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.554 | 1.684 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.25961</span> | 100.9 | 0.01701 | 0.2782 | 0.09252 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8558 | 0.07764 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6880 | 3.783 | 1.552 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.554 | 1.684 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 117</span>| 468.24351 | 1.011 | -0.9738 | -0.9538 | -0.9477 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9580 | -0.9328 | -0.5629 | -0.6029 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8899 | 0.5019 | -0.6706 | -0.4913 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1638 | -0.4360 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.24351 | 101.1 | -4.074 | -0.9537 | -2.380 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01113 | 0.8557 | 0.07762 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6880 | 3.783 | 1.552 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.554 | 1.684 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.24351</span> | 101.1 | 0.01701 | 0.2781 | 0.09252 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01728 | 0.4972 | 0.8557 | 0.07762 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6880 | 3.783 | 1.552 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.554 | 1.684 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -0.7570 | -0.04882 | -0.1901 | -0.1704 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4436 | 0.006358 | -1.944 | -2.069 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3547 | -0.6277 | -0.2411 | -0.07768 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3909 | -0.1932 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 118</span>| 468.24096 | 1.012 | -0.9738 | -0.9538 | -0.9477 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9579 | -0.9328 | -0.5622 | -0.6021 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8898 | 0.5021 | -0.6705 | -0.4913 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1637 | -0.4360 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.24096 | 101.2 | -4.074 | -0.9536 | -2.380 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01113 | 0.8559 | 0.07765 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6881 | 3.784 | 1.552 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.554 | 1.684 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.24096</span> | 101.2 | 0.01701 | 0.2782 | 0.09252 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8559 | 0.07765 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6881 | 3.784 | 1.552 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.554 | 1.684 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.456 | 0.1549 | -0.1619 | -0.1892 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4078 | 0.006267 | -1.860 | -2.735 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3543 | -0.6265 | -0.1851 | -0.08656 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3612 | -0.1856 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 119</span>| 468.23716 | 1.012 | -0.9738 | -0.9536 | -0.9467 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9576 | -0.9329 | -0.5614 | -0.6008 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8898 | 0.5037 | -0.6704 | -0.4911 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1638 | -0.4357 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.23716 | 101.2 | -4.074 | -0.9534 | -2.379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01113 | 0.8562 | 0.07769 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6881 | 3.786 | 1.552 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.554 | 1.684 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.23716</span> | 101.2 | 0.01701 | 0.2782 | 0.09261 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8562 | 0.07769 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6881 | 3.786 | 1.552 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.554 | 1.684 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.250 | 0.2329 | -0.1405 | -0.1467 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3393 | 0.006453 | -1.023 | -1.889 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3583 | -0.6239 | -0.2353 | -0.09107 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3636 | -0.1837 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 120</span>| 468.26529 | 1.008 | -0.9742 | -0.9534 | -0.9465 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9571 | -0.9329 | -0.5599 | -0.5980 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8893 | 0.5046 | -0.6700 | -0.4910 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1633 | -0.4354 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.26529 | 100.8 | -4.074 | -0.9532 | -2.379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01113 | 0.8568 | 0.07778 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6884 | 3.788 | 1.553 | 1.621 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.555 | 1.685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.26529</span> | 100.8 | 0.01701 | 0.2782 | 0.09263 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8568 | 0.07778 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6884 | 3.788 | 1.553 | 1.621 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.555 | 1.685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 121</span>| 468.23604 | 1.011 | -0.9739 | -0.9535 | -0.9467 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9575 | -0.9329 | -0.5612 | -0.6003 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8897 | 0.5039 | -0.6703 | -0.4911 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1637 | -0.4357 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.23604 | 101.1 | -4.074 | -0.9534 | -2.379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01113 | 0.8563 | 0.07771 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6881 | 3.786 | 1.552 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.554 | 1.684 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.23604</span> | 101.1 | 0.01701 | 0.2782 | 0.09261 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8563 | 0.07771 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6881 | 3.786 | 1.552 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.554 | 1.684 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.188 | -0.1927 | -0.1868 | -0.1045 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2665 | 0.006857 | -1.024 | -1.172 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2153 | -0.6125 | -0.1502 | -0.07921 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3902 | -0.1918 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 122</span>| 468.23464 | 1.012 | -0.9738 | -0.9534 | -0.9465 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9574 | -0.9329 | -0.5609 | -0.6000 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8895 | 0.5043 | -0.6702 | -0.4911 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1635 | -0.4356 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.23464 | 101.2 | -4.074 | -0.9533 | -2.379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01113 | 0.8564 | 0.07772 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6883 | 3.787 | 1.552 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.555 | 1.684 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.23464</span> | 101.2 | 0.01701 | 0.2782 | 0.09263 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8564 | 0.07772 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6883 | 3.787 | 1.552 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.555 | 1.684 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.857 | 0.1925 | -0.1360 | -0.1332 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2859 | 0.006578 | -0.9819 | -1.076 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2136 | -0.6087 | -0.2154 | -0.09459 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3609 | -0.1836 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 123</span>| 468.23346 | 1.011 | -0.9739 | -0.9532 | -0.9463 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9574 | -0.9329 | -0.5607 | -0.5998 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8893 | 0.5049 | -0.6701 | -0.4911 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1633 | -0.4355 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.23346 | 101.1 | -4.074 | -0.9531 | -2.379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01113 | 0.8565 | 0.07772 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6884 | 3.788 | 1.552 | 1.621 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.555 | 1.684 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.23346</span> | 101.1 | 0.01701 | 0.2783 | 0.09265 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8565 | 0.07772 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6884 | 3.788 | 1.552 | 1.621 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.555 | 1.684 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.112 | -0.08635 | -0.1600 | -0.09176 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2402 | 0.006873 | -0.9941 | -1.084 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2133 | -0.6080 | -0.2006 | -0.08423 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.3853 | -0.1906 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 124</span>| 468.23209 | 1.012 | -0.9738 | -0.9531 | -0.9461 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9573 | -0.9329 | -0.5604 | -0.5995 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8891 | 0.5054 | -0.6700 | -0.4910 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1631 | -0.4354 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.23209 | 101.2 | -4.074 | -0.9530 | -2.379 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01113 | 0.8566 | 0.07774 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6885 | 3.789 | 1.553 | 1.621 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.555 | 1.685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.23209</span> | 101.2 | 0.01701 | 0.2783 | 0.09266 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8566 | 0.07774 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6885 | 3.789 | 1.553 | 1.621 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.555 | 1.685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 125</span>| 468.23061 | 1.012 | -0.9738 | -0.9526 | -0.9453 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9573 | -0.9330 | -0.5604 | -0.5995 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8885 | 0.5071 | -0.6698 | -0.4911 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1626 | -0.4353 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.23061 | 101.2 | -4.074 | -0.9525 | -2.378 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01113 | 0.8566 | 0.07773 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6889 | 3.791 | 1.553 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.556 | 1.685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.23061</span> | 101.2 | 0.01701 | 0.2784 | 0.09274 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8566 | 0.07773 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6889 | 3.791 | 1.553 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.556 | 1.685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 126</span>| 468.22552 | 1.012 | -0.9738 | -0.9506 | -0.9419 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9573 | -0.9333 | -0.5606 | -0.5998 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8861 | 0.5138 | -0.6689 | -0.4912 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1606 | -0.4347 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.22552 | 101.2 | -4.074 | -0.9506 | -2.375 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01113 | 0.8565 | 0.07773 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6906 | 3.802 | 1.554 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.559 | 1.685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.22552</span> | 101.2 | 0.01701 | 0.2788 | 0.09305 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8565 | 0.07773 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6906 | 3.802 | 1.554 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.559 | 1.685 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 127</span>| 468.21689 | 1.012 | -0.9737 | -0.9426 | -0.9286 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9574 | -0.9344 | -0.5614 | -0.6009 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8763 | 0.5405 | -0.6653 | -0.4919 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1525 | -0.4325 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.21689 | 101.2 | -4.074 | -0.9431 | -2.361 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01114 | 0.8562 | 0.07769 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6972 | 3.844 | 1.558 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.571 | 1.688 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.21689</span> | 101.2 | 0.01701 | 0.2803 | 0.09430 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8562 | 0.07769 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.6972 | 3.844 | 1.558 | 1.620 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.571 | 1.688 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.525 | 0.5842 | 0.4183 | 0.9468 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.5439 | 0.008618 | -1.874 | -1.936 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2463 | -0.5498 | 0.04440 | -0.1490 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.2038 | -0.1015 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 128</span>| 468.19158 | 1.011 | -0.9737 | -0.9504 | -0.9293 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9577 | -0.9362 | -0.5600 | -0.6009 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8523 | 0.5756 | -0.6644 | -0.4878 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1417 | -0.4298 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.19158 | 101.1 | -4.074 | -0.9504 | -2.362 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01116 | 0.8567 | 0.07769 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7134 | 3.900 | 1.560 | 1.624 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.587 | 1.691 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.19158</span> | 101.1 | 0.01701 | 0.2788 | 0.09423 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8567 | 0.07769 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7134 | 3.900 | 1.560 | 1.624 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.587 | 1.691 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -7.990 | 0.8226 | -0.02734 | 0.9308 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.6358 | 0.008756 | -3.089 | -2.706 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.08468 | -0.5047 | 0.1760 | -0.08785 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.06839 | -0.06706 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 129</span>| 468.16872 | 1.012 | -0.9746 | -0.9536 | -0.9297 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9583 | -0.9383 | -0.5551 | -0.6021 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8428 | 0.6190 | -0.6652 | -0.4874 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1424 | -0.4276 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.16872 | 101.2 | -4.075 | -0.9534 | -2.362 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.058 | -0.01118 | 0.8585 | 0.07765 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7198 | 3.968 | 1.559 | 1.625 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.586 | 1.694 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.16872</span> | 101.2 | 0.01700 | 0.2782 | 0.09420 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01728 | 0.4972 | 0.8585 | 0.07765 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7198 | 3.968 | 1.559 | 1.625 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.586 | 1.694 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 1.949 | 1.224 | -0.09904 | 0.8335 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8902 | 0.008091 | -1.732 | -1.975 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.02618 | -0.4349 | 0.2067 | -0.1419 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.09587 | -0.05531 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 130</span>| 468.14579 | 1.011 | -0.9759 | -0.9465 | -0.9356 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9575 | -0.9407 | -0.5519 | -0.5999 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8420 | 0.6626 | -0.6664 | -0.4855 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1418 | -0.4273 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.14579 | 101.1 | -4.076 | -0.9467 | -2.368 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01121 | 0.8597 | 0.07772 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7204 | 4.037 | 1.557 | 1.627 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.587 | 1.694 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.14579</span> | 101.1 | 0.01698 | 0.2795 | 0.09364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4972 | 0.8597 | 0.07772 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7204 | 4.037 | 1.557 | 1.627 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.587 | 1.694 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -9.402 | -0.5832 | 0.1847 | 0.5188 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4155 | 0.008564 | -1.671 | -1.980 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.03632 | -0.3649 | 0.3304 | -0.09551 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1039 | -0.08698 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 131</span>| 468.12514 | 1.011 | -0.9763 | -0.9445 | -0.9403 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9555 | -0.9442 | -0.5537 | -0.5953 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8391 | 0.7059 | -0.6668 | -0.4805 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1376 | -0.4223 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.12514 | 101.1 | -4.076 | -0.9449 | -2.373 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.056 | -0.01125 | 0.8590 | 0.07788 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7223 | 4.106 | 1.557 | 1.633 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.593 | 1.700 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.12514</span> | 101.1 | 0.01697 | 0.2799 | 0.09320 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01733 | 0.4972 | 0.8590 | 0.07788 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7223 | 4.106 | 1.557 | 1.633 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.593 | 1.700 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -5.823 | -0.4010 | 0.3316 | 0.1628 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2993 | 0.008766 | -1.373 | -1.049 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.008284 | -0.3402 | 0.4029 | 0.04088 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.03436 | -0.04680 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 132</span>| 468.10920 | 1.012 | -0.9773 | -0.9503 | -0.9395 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9556 | -0.9476 | -0.5516 | -0.5942 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8420 | 0.7499 | -0.6684 | -0.4836 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1347 | -0.4216 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.1092 | 101.2 | -4.077 | -0.9504 | -2.372 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.056 | -0.01129 | 0.8598 | 0.07791 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7204 | 4.175 | 1.555 | 1.629 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.597 | 1.700 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.1092</span> | 101.2 | 0.01695 | 0.2788 | 0.09328 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01732 | 0.4972 | 0.8598 | 0.07791 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7204 | 4.175 | 1.555 | 1.629 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.597 | 1.700 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 0.4262 | -0.09925 | 0.1213 | 0.1364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.2200 | 0.008054 | -0.8480 | -0.9224 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.002683 | -0.2932 | 0.3866 | -0.06974 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.01820 | -0.05063 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 133</span>| 468.09766 | 1.011 | -0.9774 | -0.9506 | -0.9392 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9564 | -0.9508 | -0.5497 | -0.5929 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8318 | 0.7901 | -0.6724 | -0.4776 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1474 | -0.4133 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.09766 | 101.1 | -4.077 | -0.9507 | -2.372 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.056 | -0.01132 | 0.8605 | 0.07796 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7273 | 4.239 | 1.550 | 1.636 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.578 | 1.710 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.09766</span> | 101.1 | 0.01695 | 0.2788 | 0.09331 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01731 | 0.4972 | 0.8605 | 0.07796 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7273 | 4.239 | 1.550 | 1.636 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.578 | 1.710 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -1.610 | 0.04645 | 0.08092 | 0.1870 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1143 | 0.008788 | -0.7906 | -0.9380 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.03576 | -0.2567 | 0.2790 | 0.04583 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1853 | 0.03622 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 134</span>| 468.08577 | 1.011 | -0.9779 | -0.9521 | -0.9394 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9569 | -0.9550 | -0.5484 | -0.5900 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8316 | 0.8332 | -0.6752 | -0.4781 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1428 | -0.4231 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.08577 | 101.1 | -4.078 | -0.9520 | -2.372 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01137 | 0.8610 | 0.07805 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7274 | 4.307 | 1.546 | 1.635 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.585 | 1.699 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.08577</span> | 101.1 | 0.01694 | 0.2785 | 0.09329 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4972 | 0.8610 | 0.07805 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7274 | 4.307 | 1.546 | 1.635 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.585 | 1.699 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -2.835 | -0.08271 | 0.01028 | 0.1502 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.2859 | 0.008536 | -0.7298 | -0.7597 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.09519 | -0.2281 | 0.1720 | -0.01715 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1386 | -0.1062 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 135</span>| 468.06947 | 1.011 | -0.9795 | -0.9573 | -0.9407 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9575 | -0.9652 | -0.5443 | -0.5834 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8515 | 0.9153 | -0.6785 | -0.4834 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1291 | -0.4003 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.06947 | 101.1 | -4.080 | -0.9569 | -2.373 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01148 | 0.8625 | 0.07827 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7139 | 4.437 | 1.542 | 1.629 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.605 | 1.725 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.06947</span> | 101.1 | 0.01692 | 0.2775 | 0.09316 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01729 | 0.4971 | 0.8625 | 0.07827 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7139 | 4.437 | 1.542 | 1.629 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.605 | 1.725 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | -3.887 | -0.6407 | -0.1939 | 0.08469 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.4208 | 0.006503 | -1.301 | -1.072 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1255 | -0.1861 | 0.1431 | -0.06050 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.01658 | 0.1111 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 136</span>| 468.05012 | 1.012 | -0.9812 | -0.9547 | -0.9420 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9570 | -0.9873 | -0.5356 | -0.5736 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8556 | 1.092 | -0.6884 | -0.4796 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1211 | -0.3873 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.05012 | 101.2 | -4.081 | -0.9544 | -2.375 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01172 | 0.8656 | 0.07860 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7112 | 4.716 | 1.529 | 1.634 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.617 | 1.740 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.05012</span> | 101.2 | 0.01689 | 0.2780 | 0.09305 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4971 | 0.8656 | 0.07860 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7112 | 4.716 | 1.529 | 1.634 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.617 | 1.740 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | F| Forward Diff. | 2.331 | -0.3124 | 0.04539 | -0.09325 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.3359 | 0.005628 | -0.9294 | -0.4404 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.1788 | -0.1003 | -0.1180 | -0.02636 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 0.09915 | 0.1820 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 137</span>| 468.05341 | 1.012 | -0.9836 | -0.9687 | -0.9317 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9507 | -1.013 | -0.5235 | -0.5660 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8472 | 1.268 | -0.6904 | -0.4754 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1200 | -0.3857 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.05341 | 101.2 | -4.084 | -0.9676 | -2.364 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.051 | -0.01201 | 0.8700 | 0.07886 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7168 | 4.995 | 1.527 | 1.639 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.619 | 1.742 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.05341</span> | 101.2 | 0.01685 | 0.2754 | 0.09401 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01741 | 0.4970 | 0.8700 | 0.07886 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7168 | 4.995 | 1.527 | 1.639 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.619 | 1.742 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> |<span style="font-weight: bold;"> 138</span>| 468.05012 | 1.012 | -0.9812 | -0.9547 | -0.9420 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.9570 | -0.9873 | -0.5356 | -0.5736 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -0.8556 | 1.092 | -0.6884 | -0.4796 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| -0.1211 | -0.3873 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | U| 468.05012 | 101.2 | -4.081 | -0.9544 | -2.375 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| -4.057 | -0.01172 | 0.8656 | 0.07860 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7112 | 4.716 | 1.529 | 1.634 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.617 | 1.740 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> | X|<span style="font-weight: bold;"> 468.05012</span> | 101.2 | 0.01689 | 0.2780 | 0.09305 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.01730 | 0.4971 | 0.8656 | 0.07860 |</span> +<span class="r-out co"><span class="r-pr">#></span> |.....................| 0.7112 | 4.716 | 1.529 | 1.634 |</span> +<span class="r-out co"><span class="r-pr">#></span> <span style="text-decoration: underline;">|.....................| 2.617 | 1.740 |...........|...........|</span></span> +<span class="r-out co"><span class="r-pr">#></span> calculating covariance matrix</span> +<span class="r-out co"><span class="r-pr">#></span> done</span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating residuals/tables</span> +<span class="r-msg co"><span class="r-pr">#></span> done</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/stats/AIC.html" class="external-link">AIC</a></span><span class="op">(</span><span class="va">f_nlmixr_dfop_sfo_saem</span><span class="op">$</span><span class="va">nm</span>, <span class="va">f_nlmixr_dfop_sfo_focei</span><span class="op">$</span><span class="va">nm</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Calculating -2LL by Gaussian quadrature (nnodes=3,nsd=1.6)</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> df AIC</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_dfop_sfo_saem$nm 16 1105.3725</span> +<span class="r-out co"><span class="r-pr">#></span> f_nlmixr_dfop_sfo_focei$nm 14 810.3271</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/saemix/man/summary-methods.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">f_nlmixr_dfop_sfo_sfo</span>, data <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in h(simpleError(msg, call)):</span> error in evaluating the argument 'object' in selecting a method for function 'summary': object 'f_nlmixr_dfop_sfo_sfo' not found</span> +<span class="r-in"><span class="co"># }</span></span> +<span class="r-in"></span> +</code></pre></div> + </div> + </div> + <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> +</div> + + + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> +</div> + +<div class="pkgdown"> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> +</div> + + </footer></div> + + + + + + + </body></html> + diff --git a/docs/reference/summary.saem.mmkin.html b/docs/reference/summary.saem.mmkin.html new file mode 100644 index 00000000..2fe81023 --- /dev/null +++ b/docs/reference/summary.saem.mmkin.html @@ -0,0 +1,230 @@ +<!DOCTYPE html> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Summary method for class "saem.mmkin" — summary.saem.mmkin • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Summary method for class " saem.mmkin summary.saem.mmkin><meta property="og:description" content="Lists model equations, initial parameter values, optimised parameters +for fixed effects (population), random effects (deviations from the +population mean) and residual error model, as well as the resulting +endpoints such as formation fractions and DT50 values. Optionally +(default is FALSE), the data are listed in full."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> +<script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> +<script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + + + <div class="container template-reference-topic"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <div class="container"> + <div class="navbar-header"> + <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> + <span class="sr-only">Toggle navigation</span> + <span class="icon-bar"></span> + <span class="icon-bar"></span> + <span class="icon-bar"></span> + </button> + <span class="navbar-brand"> + <a class="navbar-link" href="../index.html">mkin</a> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> + </span> + </div> + + <div id="navbar" class="navbar-collapse collapse"> + <ul class="nav navbar-nav"><li> + <a href="../reference/index.html">Functions and data</a> +</li> +<li class="dropdown"> + <a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-expanded="false"> + Articles + + <span class="caret"></span> + </a> + <ul class="dropdown-menu" role="menu"><li> + <a href="../articles/mkin.html">Introduction to mkin</a> + </li> + <li> + <a href="../articles/FOCUS_D.html">Example evaluation of FOCUS Example Dataset D</a> + </li> + <li> + <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> + </li> + <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> + <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> + </li> + <li> + <a href="../articles/web_only/compiled_models.html">Performance benefit by using compiled model definitions in mkin</a> + </li> + <li> + <a href="../articles/twa.html">Calculation of time weighted average concentrations with mkin</a> + </li> + <li> + <a href="../articles/web_only/NAFTA_examples.html">Example evaluation of NAFTA SOP Attachment examples</a> + </li> + <li> + <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> + </li> + </ul></li> +<li> + <a href="../news/index.html">News</a> +</li> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> + <span class="fab fa-github fa-lg"></span> + + </a> +</li> + </ul></div><!--/.nav-collapse --> + </div><!--/.container --> +</div><!--/.navbar --> + + + + </header><div class="row"> + <div class="col-md-9 contents"> + <div class="page-header"> + <h1>Summary method for class "saem.mmkin"</h1> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/summary.saem.mmkin.R" class="external-link"><code>R/summary.saem.mmkin.R</code></a></small> + <div class="hidden name"><code>summary.saem.mmkin.Rd</code></div> + </div> + + <div class="ref-description"> + <p>Lists model equations, initial parameter values, optimised parameters +for fixed effects (population), random effects (deviations from the +population mean) and residual error model, as well as the resulting +endpoints such as formation fractions and DT50 values. Optionally +(default is FALSE), the data are listed in full.</p> + </div> + + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for saem.mmkin</span> +<span class="fu"><a href="https://rdrr.io/pkg/saemix/man/summary-methods.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">object</span>, data <span class="op">=</span> <span class="cn">FALSE</span>, verbose <span class="op">=</span> <span class="cn">FALSE</span>, distimes <span class="op">=</span> <span class="cn">TRUE</span>, <span class="va">...</span><span class="op">)</span> + +<span class="co"># S3 method for summary.saem.mmkin</span> +<span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">x</span>, digits <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/Extremes.html" class="external-link">max</a></span><span class="op">(</span><span class="fl">3</span>, <span class="fu"><a href="https://rdrr.io/r/base/options.html" class="external-link">getOption</a></span><span class="op">(</span><span class="st">"digits"</span><span class="op">)</span> <span class="op">-</span> <span class="fl">3</span><span class="op">)</span>, verbose <span class="op">=</span> <span class="va">x</span><span class="op">$</span><span class="va">verbose</span>, <span class="va">...</span><span class="op">)</span></code></pre></div> + </div> + + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>an object of class <a href="saem.html">saem.mmkin</a></p></dd> +<dt>data</dt> +<dd><p>logical, indicating whether the full data should be included in +the summary.</p></dd> +<dt>verbose</dt> +<dd><p>Should the summary be verbose?</p></dd> +<dt>distimes</dt> +<dd><p>logical, indicating whether DT50 and DT90 values should be +included.</p></dd> +<dt>...</dt> +<dd><p>optional arguments passed to methods like <code>print</code>.</p></dd> +<dt>x</dt> +<dd><p>an object of class summary.saem.mmkin</p></dd> +<dt>digits</dt> +<dd><p>Number of digits to use for printing</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>The summary function returns a list based on the <a href="https://rdrr.io/pkg/saemix/man/SaemixObject-class.html" class="external-link">saemix::SaemixObject</a>obtained in the fit, with at least the following additional components</p> +<dl><dt>saemixversion, mkinversion, Rversion</dt> +<dd><p>The saemix, mkin and R versions used</p></dd> +<dt>date.fit, date.summary</dt> +<dd><p>The dates where the fit and the summary were +produced</p></dd> +<dt>diffs</dt> +<dd><p>The differential equations used in the degradation model</p></dd> +<dt>use_of_ff</dt> +<dd><p>Was maximum or minimum use made of formation fractions</p></dd> +<dt>data</dt> +<dd><p>The data</p></dd> +<dt>confint_trans</dt> +<dd><p>Transformed parameters as used in the optimisation, with confidence intervals</p></dd> +<dt>confint_back</dt> +<dd><p>Backtransformed parameters, with confidence intervals if available</p></dd> +<dt>confint_errmod</dt> +<dd><p>Error model parameters with confidence intervals</p></dd> +<dt>ff</dt> +<dd><p>The estimated formation fractions derived from the fitted +model.</p></dd> +<dt>distimes</dt> +<dd><p>The DT50 and DT90 values for each observed variable.</p></dd> +<dt>SFORB</dt> +<dd><p>If applicable, eigenvalues of SFORB components of the model.</p></dd> +</dl><p>The print method is called for its side effect, i.e. printing the summary.</p> + </div> + <div id="author"> + <h2>Author</h2> + <p>Johannes Ranke for the mkin specific parts +saemix authors for the parts inherited from saemix.</p> + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="co"># Generate five datasets following DFOP-SFO kinetics</span></span> +<span class="r-in"><span class="va">sampling_times</span> <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">1</span>, <span class="fl">3</span>, <span class="fl">7</span>, <span class="fl">14</span>, <span class="fl">28</span>, <span class="fl">60</span>, <span class="fl">90</span>, <span class="fl">120</span><span class="op">)</span></span> +<span class="r-in"><span class="va">dfop_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"DFOP"</span>, <span class="st">"m1"</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/Random.html" class="external-link">set.seed</a></span><span class="op">(</span><span class="fl">1234</span><span class="op">)</span></span> +<span class="r-in"><span class="va">k1_in</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/Lognormal.html" class="external-link">rlnorm</a></span><span class="op">(</span><span class="fl">5</span>, <span class="fu"><a href="https://rdrr.io/r/base/Log.html" class="external-link">log</a></span><span class="op">(</span><span class="fl">0.1</span><span class="op">)</span>, <span class="fl">0.3</span><span class="op">)</span></span> +<span class="r-in"><span class="va">k2_in</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/Lognormal.html" class="external-link">rlnorm</a></span><span class="op">(</span><span class="fl">5</span>, <span class="fu"><a href="https://rdrr.io/r/base/Log.html" class="external-link">log</a></span><span class="op">(</span><span class="fl">0.02</span><span class="op">)</span>, <span class="fl">0.3</span><span class="op">)</span></span> +<span class="r-in"><span class="va">g_in</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/Logistic.html" class="external-link">plogis</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/stats/Normal.html" class="external-link">rnorm</a></span><span class="op">(</span><span class="fl">5</span>, <span class="fu"><a href="https://rdrr.io/r/stats/Logistic.html" class="external-link">qlogis</a></span><span class="op">(</span><span class="fl">0.5</span><span class="op">)</span>, <span class="fl">0.3</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_parent_to_m1_in</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/Logistic.html" class="external-link">plogis</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/stats/Normal.html" class="external-link">rnorm</a></span><span class="op">(</span><span class="fl">5</span>, <span class="fu"><a href="https://rdrr.io/r/stats/Logistic.html" class="external-link">qlogis</a></span><span class="op">(</span><span class="fl">0.3</span><span class="op">)</span>, <span class="fl">0.3</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"><span class="va">k_m1_in</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/Lognormal.html" class="external-link">rlnorm</a></span><span class="op">(</span><span class="fl">5</span>, <span class="fu"><a href="https://rdrr.io/r/base/Log.html" class="external-link">log</a></span><span class="op">(</span><span class="fl">0.02</span><span class="op">)</span>, <span class="fl">0.3</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">pred_dfop_sfo</span> <span class="op"><-</span> <span class="kw">function</span><span class="op">(</span><span class="va">k1</span>, <span class="va">k2</span>, <span class="va">g</span>, <span class="va">f_parent_to_m1</span>, <span class="va">k_m1</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="fu"><a href="mkinpredict.html">mkinpredict</a></span><span class="op">(</span><span class="va">dfop_sfo</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k1 <span class="op">=</span> <span class="va">k1</span>, k2 <span class="op">=</span> <span class="va">k2</span>, g <span class="op">=</span> <span class="va">g</span>, f_parent_to_m1 <span class="op">=</span> <span class="va">f_parent_to_m1</span>, k_m1 <span class="op">=</span> <span class="va">k_m1</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span>, m1 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">sampling_times</span><span class="op">)</span></span> +<span class="r-in"><span class="op">}</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">ds_mean_dfop_sfo</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="fl">1</span><span class="op">:</span><span class="fl">5</span>, <span class="kw">function</span><span class="op">(</span><span class="va">i</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="fu"><a href="mkinpredict.html">mkinpredict</a></span><span class="op">(</span><span class="va">dfop_sfo</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k1 <span class="op">=</span> <span class="va">k1_in</span><span class="op">[</span><span class="va">i</span><span class="op">]</span>, k2 <span class="op">=</span> <span class="va">k2_in</span><span class="op">[</span><span class="va">i</span><span class="op">]</span>, g <span class="op">=</span> <span class="va">g_in</span><span class="op">[</span><span class="va">i</span><span class="op">]</span>,</span> +<span class="r-in"> f_parent_to_m1 <span class="op">=</span> <span class="va">f_parent_to_m1_in</span><span class="op">[</span><span class="va">i</span><span class="op">]</span>, k_m1 <span class="op">=</span> <span class="va">k_m1_in</span><span class="op">[</span><span class="va">i</span><span class="op">]</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span>, m1 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">sampling_times</span><span class="op">)</span></span> +<span class="r-in"><span class="op">}</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">ds_mean_dfop_sfo</span><span class="op">)</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste</a></span><span class="op">(</span><span class="st">"ds"</span>, <span class="fl">1</span><span class="op">:</span><span class="fl">5</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">ds_syn_dfop_sfo</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">lapply</a></span><span class="op">(</span><span class="va">ds_mean_dfop_sfo</span>, <span class="kw">function</span><span class="op">(</span><span class="va">ds</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="fu"><a href="add_err.html">add_err</a></span><span class="op">(</span><span class="va">ds</span>,</span> +<span class="r-in"> sdfunc <span class="op">=</span> <span class="kw">function</span><span class="op">(</span><span class="va">value</span><span class="op">)</span> <span class="fu"><a href="https://rdrr.io/r/base/MathFun.html" class="external-link">sqrt</a></span><span class="op">(</span><span class="fl">1</span><span class="op">^</span><span class="fl">2</span> <span class="op">+</span> <span class="va">value</span><span class="op">^</span><span class="fl">2</span> <span class="op">*</span> <span class="fl">0.07</span><span class="op">^</span><span class="fl">2</span><span class="op">)</span>,</span> +<span class="r-in"> n <span class="op">=</span> <span class="fl">1</span><span class="op">)</span><span class="op">[[</span><span class="fl">1</span><span class="op">]</span><span class="op">]</span></span> +<span class="r-in"><span class="op">}</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="co"># Evaluate using mmkin and saem</span></span> +<span class="r-in"><span class="va">f_mmkin_dfop_sfo</span> <span class="op"><-</span> <span class="fu"><a href="mmkin.html">mmkin</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="va">dfop_sfo</span><span class="op">)</span>, <span class="va">ds_syn_dfop_sfo</span>,</span> +<span class="r-in"> quiet <span class="op">=</span> <span class="cn">TRUE</span>, error_model <span class="op">=</span> <span class="st">"tc"</span>, cores <span class="op">=</span> <span class="fl">5</span><span class="op">)</span></span> +<span class="r-in"><span class="va">f_saem_dfop_sfo</span> <span class="op"><-</span> <span class="fu"><a href="saem.html">saem</a></span><span class="op">(</span><span class="va">f_mmkin_dfop_sfo</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> </span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in rxModelVars_(obj):</span> Not compatible with STRSXP: [type=NULL].</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/pkg/saemix/man/summary-methods.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">f_saem_dfop_sfo</span>, data <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-err co"><span class="r-pr">#></span> <span class="error">Error in h(simpleError(msg, call)):</span> error in evaluating the argument 'object' in selecting a method for function 'summary': object 'f_saem_dfop_sfo' not found</span> +<span class="r-in"><span class="co"># }</span></span> +<span class="r-in"></span> +</code></pre></div> + </div> + </div> + <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> +</div> + + + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> +</div> + +<div class="pkgdown"> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> +</div> + + </footer></div> + + + + + + + </body></html> + diff --git a/docs/reference/synthetic_data_for_UBA_2014-1.png b/docs/reference/synthetic_data_for_UBA_2014-1.png Binary files differindex 89975db5..132380a8 100644 --- a/docs/reference/synthetic_data_for_UBA_2014-1.png +++ b/docs/reference/synthetic_data_for_UBA_2014-1.png diff --git a/docs/reference/synthetic_data_for_UBA_2014.html b/docs/reference/synthetic_data_for_UBA_2014.html index c37b986e..7d79341c 100644 --- a/docs/reference/synthetic_data_for_UBA_2014.html +++ b/docs/reference/synthetic_data_for_UBA_2014.html @@ -1,46 +1,5 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Synthetic datasets for one parent compound with two metabolites — synthetic_data_for_UBA_2014 • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Synthetic datasets for one parent compound with two metabolites — synthetic_data_for_UBA_2014" /> -<meta property="og:description" content="The 12 datasets were generated using four different models and three different +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Synthetic datasets for one parent compound with two metabolites — synthetic_data_for_UBA_2014 • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Synthetic datasets for one parent compound with two metabolites — synthetic_data_for_UBA_2014"><meta property="og:description" content="The 12 datasets were generated using four different models and three different variance components. The four models are either the SFO or the DFOP model with either two sequential or two parallel metabolites. Variance component 'a' is based on a normal distribution with standard deviation of 3, @@ -55,28 +14,14 @@ Initial concentrations for metabolites and all values where adding the variance in a value below the assumed limit of detection of 0.1 were set to NA. As an example, the first dataset has the title SFO_lin_a and is based on the SFO model with two sequential metabolites (linear pathway), with added variance component 'a'. -Compare also the code in the example section to see the degradation models." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +Compare also the code in the example section to see the degradation models."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -87,13 +32,12 @@ Compare also the code in the example section to see the degradation models." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -102,8 +46,7 @@ Compare also the code in the example section to see the degradation models." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -113,6 +56,9 @@ Compare also the code in the example section to see the degradation models." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -127,30 +73,23 @@ Compare also the code in the example section to see the degradation models." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Synthetic datasets for one parent compound with two metabolites</h1> @@ -177,300 +116,308 @@ Compare also the code in the example section to see the degradation models." /> <p>Compare also the code in the example section to see the degradation models.</p> </div> - <pre class="usage"><span class='va'>synthetic_data_for_UBA_2014</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="va">synthetic_data_for_UBA_2014</span></code></pre></div> + </div> + <div id="format"> + <h2>Format</h2> + <p>A list containing twelve datasets as an R6 class defined by <code><a href="mkinds.html">mkinds</a></code>, + each containing, among others, the following components</p><dl><dt><code>title</code></dt> +<dd><p>The name of the dataset, e.g. <code>SFO_lin_a</code></p></dd> - <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2> + <dt><code>data</code></dt> +<dd><p>A data frame with the data in the form expected by <code><a href="mkinfit.html">mkinfit</a></code></p></dd> - <p>A list containing twelve datasets as an R6 class defined by <code><a href='mkinds.html'>mkinds</a></code>, - each containing, among others, the following components</p><dl> - <dt><code>title</code></dt><dd><p>The name of the dataset, e.g. <code>SFO_lin_a</code></p></dd> - <dt><code>data</code></dt><dd><p>A data frame with the data in the form expected by <code><a href='mkinfit.html'>mkinfit</a></code></p></dd> -</dl> - - <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2> - +</dl></div> + <div id="source"> + <h2>Source</h2> <p>Ranke (2014) Prüfung und Validierung von Modellierungssoftware als Alternative zu ModelMaker 4.0, Umweltbundesamt Projektnummer 27452</p> <p>Rocke, David M. und Lorenzato, Stefan (1995) A two-component model for measurement error in analytical chemistry. Technometrics 37(2), 176-184.</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='co'># \dontrun{</span> -<span class='co'># The data have been generated using the following kinetic models</span> -<span class='va'>m_synth_SFO_lin</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"M1"</span><span class='op'>)</span>, - M1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"M2"</span><span class='op'>)</span>, - M2 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> - -<span class='va'>m_synth_SFO_par</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"M1"</span>, <span class='st'>"M2"</span><span class='op'>)</span>, - sink <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span>, - M1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, - M2 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> -<span class='va'>m_synth_DFOP_lin</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"DFOP"</span>, to <span class='op'>=</span> <span class='st'>"M1"</span><span class='op'>)</span>, - M1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"M2"</span><span class='op'>)</span>, - M2 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> -<span class='va'>m_synth_DFOP_par</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"DFOP"</span>, to <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"M1"</span>, <span class='st'>"M2"</span><span class='op'>)</span>, - sink <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span>, - M1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, - M2 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> -<span class='co'># The model predictions without intentional error were generated as follows</span> -<span class='va'>sampling_times</span> <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='fl'>0</span>, <span class='fl'>1</span>, <span class='fl'>3</span>, <span class='fl'>7</span>, <span class='fl'>14</span>, <span class='fl'>28</span>, <span class='fl'>60</span>, <span class='fl'>90</span>, <span class='fl'>120</span><span class='op'>)</span> - -<span class='va'>d_synth_SFO_lin</span> <span class='op'><-</span> <span class='fu'><a href='mkinpredict.html'>mkinpredict</a></span><span class='op'>(</span><span class='va'>m_synth_SFO_lin</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_parent <span class='op'>=</span> <span class='fl'>0.7</span>, f_parent_to_M1 <span class='op'>=</span> <span class='fl'>0.8</span>, - k_M1 <span class='op'>=</span> <span class='fl'>0.3</span>, f_M1_to_M2 <span class='op'>=</span> <span class='fl'>0.7</span>, - k_M2 <span class='op'>=</span> <span class='fl'>0.02</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>100</span>, M1 <span class='op'>=</span> <span class='fl'>0</span>, M2 <span class='op'>=</span> <span class='fl'>0</span><span class='op'>)</span>, - <span class='va'>sampling_times</span><span class='op'>)</span> - -<span class='va'>d_synth_DFOP_lin</span> <span class='op'><-</span> <span class='fu'><a href='mkinpredict.html'>mkinpredict</a></span><span class='op'>(</span><span class='va'>m_synth_DFOP_lin</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k1 <span class='op'>=</span> <span class='fl'>0.2</span>, k2 <span class='op'>=</span> <span class='fl'>0.02</span>, g <span class='op'>=</span> <span class='fl'>0.5</span>, - f_parent_to_M1 <span class='op'>=</span> <span class='fl'>0.5</span>, k_M1 <span class='op'>=</span> <span class='fl'>0.3</span>, - f_M1_to_M2 <span class='op'>=</span> <span class='fl'>0.7</span>, k_M2 <span class='op'>=</span> <span class='fl'>0.02</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>100</span>, M1 <span class='op'>=</span> <span class='fl'>0</span>, M2 <span class='op'>=</span> <span class='fl'>0</span><span class='op'>)</span>, - <span class='va'>sampling_times</span><span class='op'>)</span> - -<span class='va'>d_synth_SFO_par</span> <span class='op'><-</span> <span class='fu'><a href='mkinpredict.html'>mkinpredict</a></span><span class='op'>(</span><span class='va'>m_synth_SFO_par</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k_parent <span class='op'>=</span> <span class='fl'>0.2</span>, - f_parent_to_M1 <span class='op'>=</span> <span class='fl'>0.8</span>, k_M1 <span class='op'>=</span> <span class='fl'>0.01</span>, - f_parent_to_M2 <span class='op'>=</span> <span class='fl'>0.2</span>, k_M2 <span class='op'>=</span> <span class='fl'>0.02</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>100</span>, M1 <span class='op'>=</span> <span class='fl'>0</span>, M2 <span class='op'>=</span> <span class='fl'>0</span><span class='op'>)</span>, - <span class='va'>sampling_times</span><span class='op'>)</span> - -<span class='va'>d_synth_DFOP_par</span> <span class='op'><-</span> <span class='fu'><a href='mkinpredict.html'>mkinpredict</a></span><span class='op'>(</span><span class='va'>m_synth_DFOP_par</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>k1 <span class='op'>=</span> <span class='fl'>0.3</span>, k2 <span class='op'>=</span> <span class='fl'>0.02</span>, g <span class='op'>=</span> <span class='fl'>0.7</span>, - f_parent_to_M1 <span class='op'>=</span> <span class='fl'>0.6</span>, k_M1 <span class='op'>=</span> <span class='fl'>0.04</span>, - f_parent_to_M2 <span class='op'>=</span> <span class='fl'>0.4</span>, k_M2 <span class='op'>=</span> <span class='fl'>0.01</span><span class='op'>)</span>, - <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fl'>100</span>, M1 <span class='op'>=</span> <span class='fl'>0</span>, M2 <span class='op'>=</span> <span class='fl'>0</span><span class='op'>)</span>, - <span class='va'>sampling_times</span><span class='op'>)</span> - -<span class='co'># Construct names for datasets with errors</span> -<span class='va'>d_synth_names</span> <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/paste.html'>paste0</a></span><span class='op'>(</span><span class='st'>"d_synth_"</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"SFO_lin"</span>, <span class='st'>"SFO_par"</span>, - <span class='st'>"DFOP_lin"</span>, <span class='st'>"DFOP_par"</span><span class='op'>)</span><span class='op'>)</span> - -<span class='co'># Original function used or adding errors. The add_err function now published</span> -<span class='co'># with this package is a slightly generalised version where the names of</span> -<span class='co'># secondary compartments that should have an initial value of zero (M1 and M2</span> -<span class='co'># in this case) are not hardcoded any more.</span> -<span class='co'># add_err = function(d, sdfunc, LOD = 0.1, reps = 2, seed = 123456789)</span> -<span class='co'># {</span> -<span class='co'># set.seed(seed)</span> -<span class='co'># d_long = mkin_wide_to_long(d, time = "time")</span> -<span class='co'># d_rep = data.frame(lapply(d_long, rep, each = 2))</span> -<span class='co'># d_rep$value = rnorm(length(d_rep$value), d_rep$value, sdfunc(d_rep$value))</span> -<span class='co'>#</span> -<span class='co'># d_rep[d_rep$time == 0 & d_rep$name %in% c("M1", "M2"), "value"] <- 0</span> -<span class='co'># d_NA <- transform(d_rep, value = ifelse(value < LOD, NA, value))</span> -<span class='co'># d_NA$value <- round(d_NA$value, 1)</span> -<span class='co'># return(d_NA)</span> -<span class='co'># }</span> - -<span class='co'># The following is the simplified version of the two-component model of Rocke</span> -<span class='co'># and Lorenzato (1995)</span> -<span class='va'>sdfunc_twocomp</span> <span class='op'>=</span> <span class='kw'>function</span><span class='op'>(</span><span class='va'>value</span>, <span class='va'>sd_low</span>, <span class='va'>rsd_high</span><span class='op'>)</span> <span class='op'>{</span> - <span class='fu'><a href='https://rdrr.io/r/base/MathFun.html'>sqrt</a></span><span class='op'>(</span><span class='va'>sd_low</span><span class='op'>^</span><span class='fl'>2</span> <span class='op'>+</span> <span class='va'>value</span><span class='op'>^</span><span class='fl'>2</span> <span class='op'>*</span> <span class='va'>rsd_high</span><span class='op'>^</span><span class='fl'>2</span><span class='op'>)</span> -<span class='op'>}</span> - -<span class='co'># Add the errors.</span> -<span class='kw'>for</span> <span class='op'>(</span><span class='va'>d_synth_name</span> <span class='kw'>in</span> <span class='va'>d_synth_names</span><span class='op'>)</span> -<span class='op'>{</span> - <span class='va'>d_synth</span> <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/get.html'>get</a></span><span class='op'>(</span><span class='va'>d_synth_name</span><span class='op'>)</span> - <span class='fu'><a href='https://rdrr.io/r/base/assign.html'>assign</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/paste.html'>paste0</a></span><span class='op'>(</span><span class='va'>d_synth_name</span>, <span class='st'>"_a"</span><span class='op'>)</span>, <span class='fu'><a href='add_err.html'>add_err</a></span><span class='op'>(</span><span class='va'>d_synth</span>, <span class='kw'>function</span><span class='op'>(</span><span class='va'>value</span><span class='op'>)</span> <span class='fl'>3</span><span class='op'>)</span><span class='op'>)</span> - <span class='fu'><a href='https://rdrr.io/r/base/assign.html'>assign</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/paste.html'>paste0</a></span><span class='op'>(</span><span class='va'>d_synth_name</span>, <span class='st'>"_b"</span><span class='op'>)</span>, <span class='fu'><a href='add_err.html'>add_err</a></span><span class='op'>(</span><span class='va'>d_synth</span>, <span class='kw'>function</span><span class='op'>(</span><span class='va'>value</span><span class='op'>)</span> <span class='fl'>7</span><span class='op'>)</span><span class='op'>)</span> - <span class='fu'><a href='https://rdrr.io/r/base/assign.html'>assign</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/paste.html'>paste0</a></span><span class='op'>(</span><span class='va'>d_synth_name</span>, <span class='st'>"_c"</span><span class='op'>)</span>, <span class='fu'><a href='add_err.html'>add_err</a></span><span class='op'>(</span><span class='va'>d_synth</span>, - <span class='kw'>function</span><span class='op'>(</span><span class='va'>value</span><span class='op'>)</span> <span class='fu'>sdfunc_twocomp</span><span class='op'>(</span><span class='va'>value</span>, <span class='fl'>0.5</span>, <span class='fl'>0.07</span><span class='op'>)</span><span class='op'>)</span><span class='op'>)</span> - -<span class='op'>}</span> - -<span class='va'>d_synth_err_names</span> <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span> - <span class='fu'><a href='https://rdrr.io/r/base/paste.html'>paste</a></span><span class='op'>(</span><span class='fu'><a href='https://rdrr.io/r/base/rep.html'>rep</a></span><span class='op'>(</span><span class='va'>d_synth_names</span>, each <span class='op'>=</span> <span class='fl'>3</span><span class='op'>)</span>, <span class='va'>letters</span><span class='op'>[</span><span class='fl'>1</span><span class='op'>:</span><span class='fl'>3</span><span class='op'>]</span>, sep <span class='op'>=</span> <span class='st'>"_"</span><span class='op'>)</span> -<span class='op'>)</span> - -<span class='co'># This is just one example of an evaluation using the kinetic model used for</span> -<span class='co'># the generation of the data</span> - <span class='va'>fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>m_synth_SFO_lin</span>, <span class='va'>synthetic_data_for_UBA_2014</span><span class='op'>[[</span><span class='fl'>1</span><span class='op'>]</span><span class='op'>]</span><span class='op'>$</span><span class='va'>data</span>, - quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> - <span class='fu'><a href='plot.mkinfit.html'>plot_sep</a></span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span> -</div><div class='img'><img src='synthetic_data_for_UBA_2014-1.png' alt='' width='700' height='433' /></div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span> -</div><div class='output co'>#> mkin version used for fitting: 1.0.3 -#> R version used for fitting: 4.0.3 -#> Date of fit: Mon Feb 15 13:46:15 2021 -#> Date of summary: Mon Feb 15 13:46:15 2021 -#> -#> Equations: -#> d_parent/dt = - k_parent * parent -#> d_M1/dt = + f_parent_to_M1 * k_parent * parent - k_M1 * M1 -#> d_M2/dt = + f_M1_to_M2 * k_M1 * M1 - k_M2 * M2 -#> -#> Model predictions using solution type deSolve -#> -#> Fitted using 833 model solutions performed in 0.665 s -#> -#> Error model: Constant variance -#> -#> Error model algorithm: OLS -#> -#> Starting values for parameters to be optimised: -#> value type -#> parent_0 101.3500 state -#> k_parent 0.1000 deparm -#> k_M1 0.1001 deparm -#> k_M2 0.1002 deparm -#> f_parent_to_M1 0.5000 deparm -#> f_M1_to_M2 0.5000 deparm -#> -#> Starting values for the transformed parameters actually optimised: -#> value lower upper -#> parent_0 101.350000 -Inf Inf -#> log_k_parent -2.302585 -Inf Inf -#> log_k_M1 -2.301586 -Inf Inf -#> log_k_M2 -2.300587 -Inf Inf -#> f_parent_qlogis 0.000000 -Inf Inf -#> f_M1_qlogis 0.000000 -Inf Inf -#> -#> Fixed parameter values: -#> value type -#> M1_0 0 state -#> M2_0 0 state -#> -#> Results: -#> -#> AIC BIC logLik -#> 188.7274 200.3723 -87.36368 -#> -#> Optimised, transformed parameters with symmetric confidence intervals: -#> Estimate Std. Error Lower Upper -#> parent_0 102.1000 1.57000 98.8600 105.3000 -#> log_k_parent -0.3020 0.03885 -0.3812 -0.2229 -#> log_k_M1 -1.2070 0.07123 -1.3520 -1.0620 -#> log_k_M2 -3.9010 0.06571 -4.0350 -3.7670 -#> f_parent_qlogis 1.2010 0.23530 0.7216 1.6800 -#> f_M1_qlogis 0.9589 0.24890 0.4520 1.4660 -#> sigma 2.2730 0.25740 1.7490 2.7970 -#> -#> Parameter correlation: -#> parent_0 log_k_parent log_k_M1 log_k_M2 f_parent_qlogis -#> parent_0 1.000e+00 3.933e-01 -1.605e-01 2.819e-02 -4.624e-01 -#> log_k_parent 3.933e-01 1.000e+00 -4.082e-01 7.166e-02 -5.682e-01 -#> log_k_M1 -1.605e-01 -4.082e-01 1.000e+00 -3.929e-01 7.478e-01 -#> log_k_M2 2.819e-02 7.166e-02 -3.929e-01 1.000e+00 -2.658e-01 -#> f_parent_qlogis -4.624e-01 -5.682e-01 7.478e-01 -2.658e-01 1.000e+00 -#> f_M1_qlogis 1.614e-01 4.102e-01 -8.109e-01 5.419e-01 -8.605e-01 -#> sigma -2.900e-08 -8.030e-09 -2.741e-08 3.938e-08 -2.681e-08 -#> f_M1_qlogis sigma -#> parent_0 1.614e-01 -2.900e-08 -#> log_k_parent 4.102e-01 -8.030e-09 -#> log_k_M1 -8.109e-01 -2.741e-08 -#> log_k_M2 5.419e-01 3.938e-08 -#> f_parent_qlogis -8.605e-01 -2.681e-08 -#> f_M1_qlogis 1.000e+00 4.971e-08 -#> sigma 4.971e-08 1.000e+00 -#> -#> Backtransformed parameters: -#> Confidence intervals for internally transformed parameters are asymmetric. -#> t-test (unrealistically) based on the assumption of normal distribution -#> for estimators of untransformed parameters. -#> Estimate t value Pr(>t) Lower Upper -#> parent_0 102.10000 65.000 7.281e-36 98.86000 105.30000 -#> k_parent 0.73930 25.740 2.948e-23 0.68310 0.80020 -#> k_M1 0.29920 14.040 1.577e-15 0.25880 0.34590 -#> k_M2 0.02023 15.220 1.653e-16 0.01769 0.02312 -#> f_parent_to_M1 0.76870 18.370 7.295e-19 0.67300 0.84290 -#> f_M1_to_M2 0.72290 14.500 6.418e-16 0.61110 0.81240 -#> sigma 2.27300 8.832 2.161e-10 1.74900 2.79700 -#> -#> FOCUS Chi2 error levels in percent: -#> err.min n.optim df -#> All data 8.454 6 17 -#> parent 8.660 2 6 -#> M1 10.583 2 5 -#> M2 3.586 2 6 -#> -#> Resulting formation fractions: -#> ff -#> parent_M1 0.7687 -#> parent_sink 0.2313 -#> M1_M2 0.7229 -#> M1_sink 0.2771 -#> -#> Estimated disappearance times: -#> DT50 DT90 -#> parent 0.9376 3.114 -#> M1 2.3170 7.697 -#> M2 34.2689 113.839 -#> -#> Data: -#> time variable observed predicted residual -#> 0 parent 101.5 1.021e+02 -0.56248 -#> 0 parent 101.2 1.021e+02 -0.86248 -#> 1 parent 53.9 4.873e+01 5.17118 -#> 1 parent 47.5 4.873e+01 -1.22882 -#> 3 parent 10.4 1.111e+01 -0.70773 -#> 3 parent 7.6 1.111e+01 -3.50773 -#> 7 parent 1.1 5.772e-01 0.52283 -#> 7 parent 0.3 5.772e-01 -0.27717 -#> 14 parent 3.5 3.264e-03 3.49674 -#> 28 parent 3.2 1.045e-07 3.20000 -#> 90 parent 0.6 9.530e-10 0.60000 -#> 120 parent 3.5 -5.940e-10 3.50000 -#> 1 M1 36.4 3.479e+01 1.61088 -#> 1 M1 37.4 3.479e+01 2.61088 -#> 3 M1 34.3 3.937e+01 -5.07027 -#> 3 M1 39.8 3.937e+01 0.42973 -#> 7 M1 15.1 1.549e+01 -0.38715 -#> 7 M1 17.8 1.549e+01 2.31285 -#> 14 M1 5.8 1.995e+00 3.80469 -#> 14 M1 1.2 1.995e+00 -0.79531 -#> 60 M1 0.5 2.111e-06 0.50000 -#> 90 M1 3.2 -9.670e-10 3.20000 -#> 120 M1 1.5 7.670e-10 1.50000 -#> 120 M1 0.6 7.670e-10 0.60000 -#> 1 M2 4.8 4.455e+00 0.34517 -#> 3 M2 20.9 2.153e+01 -0.62527 -#> 3 M2 19.3 2.153e+01 -2.22527 -#> 7 M2 42.0 4.192e+01 0.07941 -#> 7 M2 43.1 4.192e+01 1.17941 -#> 14 M2 49.4 4.557e+01 3.83353 -#> 14 M2 44.3 4.557e+01 -1.26647 -#> 28 M2 34.6 3.547e+01 -0.87275 -#> 28 M2 33.0 3.547e+01 -2.47275 -#> 60 M2 18.8 1.858e+01 0.21837 -#> 60 M2 17.6 1.858e+01 -0.98163 -#> 90 M2 10.6 1.013e+01 0.47130 -#> 90 M2 10.8 1.013e+01 0.67130 -#> 120 M2 9.8 5.521e+00 4.27893 -#> 120 M2 3.3 5.521e+00 -2.22107</div><div class='input'><span class='co'># }</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="co"># The data have been generated using the following kinetic models</span></span> +<span class="r-in"><span class="va">m_synth_SFO_lin</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"M1"</span><span class="op">)</span>,</span> +<span class="r-in"> M1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"M2"</span><span class="op">)</span>,</span> +<span class="r-in"> M2 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>, use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">m_synth_SFO_par</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"M1"</span>, <span class="st">"M2"</span><span class="op">)</span>,</span> +<span class="r-in"> sink <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span>,</span> +<span class="r-in"> M1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> M2 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>, use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">m_synth_DFOP_lin</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"DFOP"</span>, to <span class="op">=</span> <span class="st">"M1"</span><span class="op">)</span>,</span> +<span class="r-in"> M1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"M2"</span><span class="op">)</span>,</span> +<span class="r-in"> M2 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>, use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">m_synth_DFOP_par</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"DFOP"</span>, to <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"M1"</span>, <span class="st">"M2"</span><span class="op">)</span>,</span> +<span class="r-in"> sink <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span>,</span> +<span class="r-in"> M1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> M2 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>, use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># The model predictions without intentional error were generated as follows</span></span> +<span class="r-in"><span class="va">sampling_times</span> <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">0</span>, <span class="fl">1</span>, <span class="fl">3</span>, <span class="fl">7</span>, <span class="fl">14</span>, <span class="fl">28</span>, <span class="fl">60</span>, <span class="fl">90</span>, <span class="fl">120</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">d_synth_SFO_lin</span> <span class="op"><-</span> <span class="fu"><a href="mkinpredict.html">mkinpredict</a></span><span class="op">(</span><span class="va">m_synth_SFO_lin</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_parent <span class="op">=</span> <span class="fl">0.7</span>, f_parent_to_M1 <span class="op">=</span> <span class="fl">0.8</span>,</span> +<span class="r-in"> k_M1 <span class="op">=</span> <span class="fl">0.3</span>, f_M1_to_M2 <span class="op">=</span> <span class="fl">0.7</span>,</span> +<span class="r-in"> k_M2 <span class="op">=</span> <span class="fl">0.02</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span>, M1 <span class="op">=</span> <span class="fl">0</span>, M2 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">sampling_times</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">d_synth_DFOP_lin</span> <span class="op"><-</span> <span class="fu"><a href="mkinpredict.html">mkinpredict</a></span><span class="op">(</span><span class="va">m_synth_DFOP_lin</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k1 <span class="op">=</span> <span class="fl">0.2</span>, k2 <span class="op">=</span> <span class="fl">0.02</span>, g <span class="op">=</span> <span class="fl">0.5</span>,</span> +<span class="r-in"> f_parent_to_M1 <span class="op">=</span> <span class="fl">0.5</span>, k_M1 <span class="op">=</span> <span class="fl">0.3</span>,</span> +<span class="r-in"> f_M1_to_M2 <span class="op">=</span> <span class="fl">0.7</span>, k_M2 <span class="op">=</span> <span class="fl">0.02</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span>, M1 <span class="op">=</span> <span class="fl">0</span>, M2 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">sampling_times</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">d_synth_SFO_par</span> <span class="op"><-</span> <span class="fu"><a href="mkinpredict.html">mkinpredict</a></span><span class="op">(</span><span class="va">m_synth_SFO_par</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k_parent <span class="op">=</span> <span class="fl">0.2</span>,</span> +<span class="r-in"> f_parent_to_M1 <span class="op">=</span> <span class="fl">0.8</span>, k_M1 <span class="op">=</span> <span class="fl">0.01</span>,</span> +<span class="r-in"> f_parent_to_M2 <span class="op">=</span> <span class="fl">0.2</span>, k_M2 <span class="op">=</span> <span class="fl">0.02</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span>, M1 <span class="op">=</span> <span class="fl">0</span>, M2 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">sampling_times</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">d_synth_DFOP_par</span> <span class="op"><-</span> <span class="fu"><a href="mkinpredict.html">mkinpredict</a></span><span class="op">(</span><span class="va">m_synth_DFOP_par</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>k1 <span class="op">=</span> <span class="fl">0.3</span>, k2 <span class="op">=</span> <span class="fl">0.02</span>, g <span class="op">=</span> <span class="fl">0.7</span>,</span> +<span class="r-in"> f_parent_to_M1 <span class="op">=</span> <span class="fl">0.6</span>, k_M1 <span class="op">=</span> <span class="fl">0.04</span>,</span> +<span class="r-in"> f_parent_to_M2 <span class="op">=</span> <span class="fl">0.4</span>, k_M2 <span class="op">=</span> <span class="fl">0.01</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fl">100</span>, M1 <span class="op">=</span> <span class="fl">0</span>, M2 <span class="op">=</span> <span class="fl">0</span><span class="op">)</span>,</span> +<span class="r-in"> <span class="va">sampling_times</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Construct names for datasets with errors</span></span> +<span class="r-in"><span class="va">d_synth_names</span> <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste0</a></span><span class="op">(</span><span class="st">"d_synth_"</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"SFO_lin"</span>, <span class="st">"SFO_par"</span>,</span> +<span class="r-in"> <span class="st">"DFOP_lin"</span>, <span class="st">"DFOP_par"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Original function used or adding errors. The add_err function now published</span></span> +<span class="r-in"><span class="co"># with this package is a slightly generalised version where the names of</span></span> +<span class="r-in"><span class="co"># secondary compartments that should have an initial value of zero (M1 and M2</span></span> +<span class="r-in"><span class="co"># in this case) are not hardcoded any more.</span></span> +<span class="r-in"><span class="co"># add_err = function(d, sdfunc, LOD = 0.1, reps = 2, seed = 123456789)</span></span> +<span class="r-in"><span class="co"># {</span></span> +<span class="r-in"><span class="co"># set.seed(seed)</span></span> +<span class="r-in"><span class="co"># d_long = mkin_wide_to_long(d, time = "time")</span></span> +<span class="r-in"><span class="co"># d_rep = data.frame(lapply(d_long, rep, each = 2))</span></span> +<span class="r-in"><span class="co"># d_rep$value = rnorm(length(d_rep$value), d_rep$value, sdfunc(d_rep$value))</span></span> +<span class="r-in"><span class="co">#</span></span> +<span class="r-in"><span class="co"># d_rep[d_rep$time == 0 & d_rep$name %in% c("M1", "M2"), "value"] <- 0</span></span> +<span class="r-in"><span class="co"># d_NA <- transform(d_rep, value = ifelse(value < LOD, NA, value))</span></span> +<span class="r-in"><span class="co"># d_NA$value <- round(d_NA$value, 1)</span></span> +<span class="r-in"><span class="co"># return(d_NA)</span></span> +<span class="r-in"><span class="co"># }</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># The following is the simplified version of the two-component model of Rocke</span></span> +<span class="r-in"><span class="co"># and Lorenzato (1995)</span></span> +<span class="r-in"><span class="va">sdfunc_twocomp</span> <span class="op">=</span> <span class="kw">function</span><span class="op">(</span><span class="va">value</span>, <span class="va">sd_low</span>, <span class="va">rsd_high</span><span class="op">)</span> <span class="op">{</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/MathFun.html" class="external-link">sqrt</a></span><span class="op">(</span><span class="va">sd_low</span><span class="op">^</span><span class="fl">2</span> <span class="op">+</span> <span class="va">value</span><span class="op">^</span><span class="fl">2</span> <span class="op">*</span> <span class="va">rsd_high</span><span class="op">^</span><span class="fl">2</span><span class="op">)</span></span> +<span class="r-in"><span class="op">}</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Add the errors.</span></span> +<span class="r-in"><span class="kw">for</span> <span class="op">(</span><span class="va">d_synth_name</span> <span class="kw">in</span> <span class="va">d_synth_names</span><span class="op">)</span></span> +<span class="r-in"><span class="op">{</span></span> +<span class="r-in"> <span class="va">d_synth</span> <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/get.html" class="external-link">get</a></span><span class="op">(</span><span class="va">d_synth_name</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/assign.html" class="external-link">assign</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste0</a></span><span class="op">(</span><span class="va">d_synth_name</span>, <span class="st">"_a"</span><span class="op">)</span>, <span class="fu"><a href="add_err.html">add_err</a></span><span class="op">(</span><span class="va">d_synth</span>, <span class="kw">function</span><span class="op">(</span><span class="va">value</span><span class="op">)</span> <span class="fl">3</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/assign.html" class="external-link">assign</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste0</a></span><span class="op">(</span><span class="va">d_synth_name</span>, <span class="st">"_b"</span><span class="op">)</span>, <span class="fu"><a href="add_err.html">add_err</a></span><span class="op">(</span><span class="va">d_synth</span>, <span class="kw">function</span><span class="op">(</span><span class="va">value</span><span class="op">)</span> <span class="fl">7</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/assign.html" class="external-link">assign</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste0</a></span><span class="op">(</span><span class="va">d_synth_name</span>, <span class="st">"_c"</span><span class="op">)</span>, <span class="fu"><a href="add_err.html">add_err</a></span><span class="op">(</span><span class="va">d_synth</span>,</span> +<span class="r-in"> <span class="kw">function</span><span class="op">(</span><span class="va">value</span><span class="op">)</span> <span class="fu">sdfunc_twocomp</span><span class="op">(</span><span class="va">value</span>, <span class="fl">0.5</span>, <span class="fl">0.07</span><span class="op">)</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="op">}</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">d_synth_err_names</span> <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/r/base/paste.html" class="external-link">paste</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/rep.html" class="external-link">rep</a></span><span class="op">(</span><span class="va">d_synth_names</span>, each <span class="op">=</span> <span class="fl">3</span><span class="op">)</span>, <span class="va">letters</span><span class="op">[</span><span class="fl">1</span><span class="op">:</span><span class="fl">3</span><span class="op">]</span>, sep <span class="op">=</span> <span class="st">"_"</span><span class="op">)</span></span> +<span class="r-in"><span class="op">)</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># This is just one example of an evaluation using the kinetic model used for</span></span> +<span class="r-in"><span class="co"># the generation of the data</span></span> +<span class="r-in"> <span class="va">fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">m_synth_SFO_lin</span>, <span class="va">synthetic_data_for_UBA_2014</span><span class="op">[[</span><span class="fl">1</span><span class="op">]</span><span class="op">]</span><span class="op">$</span><span class="va">data</span>,</span> +<span class="r-in"> quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="plot.mkinfit.html">plot_sep</a></span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></span> +<span class="r-plt img"><img src="synthetic_data_for_UBA_2014-1.png" alt="" width="700" height="433"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/pkg/saemix/man/summary-methods.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> mkin version used for fitting: 1.1.0 </span> +<span class="r-out co"><span class="r-pr">#></span> R version used for fitting: 4.1.2 </span> +<span class="r-out co"><span class="r-pr">#></span> Date of fit: Wed Mar 2 13:44:06 2022 </span> +<span class="r-out co"><span class="r-pr">#></span> Date of summary: Wed Mar 2 13:44:06 2022 </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Equations:</span> +<span class="r-out co"><span class="r-pr">#></span> d_parent/dt = - k_parent * parent</span> +<span class="r-out co"><span class="r-pr">#></span> d_M1/dt = + f_parent_to_M1 * k_parent * parent - k_M1 * M1</span> +<span class="r-out co"><span class="r-pr">#></span> d_M2/dt = + f_M1_to_M2 * k_M1 * M1 - k_M2 * M2</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Model predictions using solution type deSolve </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fitted using 833 model solutions performed in 0.756 s</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Error model: Constant variance </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Error model algorithm: OLS </span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Starting values for parameters to be optimised:</span> +<span class="r-out co"><span class="r-pr">#></span> value type</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 101.3500 state</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.1000 deparm</span> +<span class="r-out co"><span class="r-pr">#></span> k_M1 0.1001 deparm</span> +<span class="r-out co"><span class="r-pr">#></span> k_M2 0.1002 deparm</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_M1 0.5000 deparm</span> +<span class="r-out co"><span class="r-pr">#></span> f_M1_to_M2 0.5000 deparm</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Starting values for the transformed parameters actually optimised:</span> +<span class="r-out co"><span class="r-pr">#></span> value lower upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 101.350000 -Inf Inf</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent -2.302585 -Inf Inf</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M1 -2.301586 -Inf Inf</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M2 -2.300587 -Inf Inf</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_qlogis 0.000000 -Inf Inf</span> +<span class="r-out co"><span class="r-pr">#></span> f_M1_qlogis 0.000000 -Inf Inf</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Fixed parameter values:</span> +<span class="r-out co"><span class="r-pr">#></span> value type</span> +<span class="r-out co"><span class="r-pr">#></span> M1_0 0 state</span> +<span class="r-out co"><span class="r-pr">#></span> M2_0 0 state</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Results:</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> AIC BIC logLik</span> +<span class="r-out co"><span class="r-pr">#></span> 188.7274 200.3723 -87.36368</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Optimised, transformed parameters with symmetric confidence intervals:</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Std. Error Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 102.1000 1.57000 98.8600 105.3000</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent -0.3020 0.03885 -0.3812 -0.2229</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M1 -1.2070 0.07123 -1.3520 -1.0620</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M2 -3.9010 0.06571 -4.0350 -3.7670</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_qlogis 1.2010 0.23530 0.7216 1.6800</span> +<span class="r-out co"><span class="r-pr">#></span> f_M1_qlogis 0.9589 0.24890 0.4520 1.4660</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 2.2730 0.25740 1.7490 2.7970</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Parameter correlation:</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_k_parent log_k_M1 log_k_M2 f_parent_qlogis</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 1.000e+00 3.933e-01 -1.605e-01 2.819e-02 -4.624e-01</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent 3.933e-01 1.000e+00 -4.082e-01 7.166e-02 -5.682e-01</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M1 -1.605e-01 -4.082e-01 1.000e+00 -3.929e-01 7.478e-01</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M2 2.819e-02 7.166e-02 -3.929e-01 1.000e+00 -2.658e-01</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_qlogis -4.624e-01 -5.682e-01 7.478e-01 -2.658e-01 1.000e+00</span> +<span class="r-out co"><span class="r-pr">#></span> f_M1_qlogis 1.614e-01 4.102e-01 -8.109e-01 5.419e-01 -8.605e-01</span> +<span class="r-out co"><span class="r-pr">#></span> sigma -2.900e-08 -8.030e-09 -2.741e-08 3.938e-08 -2.681e-08</span> +<span class="r-out co"><span class="r-pr">#></span> f_M1_qlogis sigma</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 1.614e-01 -2.900e-08</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent 4.102e-01 -8.030e-09</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M1 -8.109e-01 -2.741e-08</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_M2 5.419e-01 3.938e-08</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_qlogis -8.605e-01 -2.681e-08</span> +<span class="r-out co"><span class="r-pr">#></span> f_M1_qlogis 1.000e+00 4.971e-08</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 4.971e-08 1.000e+00</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Backtransformed parameters:</span> +<span class="r-out co"><span class="r-pr">#></span> Confidence intervals for internally transformed parameters are asymmetric.</span> +<span class="r-out co"><span class="r-pr">#></span> t-test (unrealistically) based on the assumption of normal distribution</span> +<span class="r-out co"><span class="r-pr">#></span> for estimators of untransformed parameters.</span> +<span class="r-out co"><span class="r-pr">#></span> Estimate t value Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 102.10000 65.000 7.281e-36 98.86000 105.30000</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.73930 25.740 2.948e-23 0.68310 0.80020</span> +<span class="r-out co"><span class="r-pr">#></span> k_M1 0.29920 14.040 1.577e-15 0.25880 0.34590</span> +<span class="r-out co"><span class="r-pr">#></span> k_M2 0.02023 15.220 1.653e-16 0.01769 0.02312</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_M1 0.76870 18.370 7.295e-19 0.67300 0.84290</span> +<span class="r-out co"><span class="r-pr">#></span> f_M1_to_M2 0.72290 14.500 6.418e-16 0.61110 0.81240</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 2.27300 8.832 2.161e-10 1.74900 2.79700</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> FOCUS Chi2 error levels in percent:</span> +<span class="r-out co"><span class="r-pr">#></span> err.min n.optim df</span> +<span class="r-out co"><span class="r-pr">#></span> All data 8.454 6 17</span> +<span class="r-out co"><span class="r-pr">#></span> parent 8.660 2 6</span> +<span class="r-out co"><span class="r-pr">#></span> M1 10.583 2 5</span> +<span class="r-out co"><span class="r-pr">#></span> M2 3.586 2 6</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Resulting formation fractions:</span> +<span class="r-out co"><span class="r-pr">#></span> ff</span> +<span class="r-out co"><span class="r-pr">#></span> parent_M1 0.7687</span> +<span class="r-out co"><span class="r-pr">#></span> parent_sink 0.2313</span> +<span class="r-out co"><span class="r-pr">#></span> M1_M2 0.7229</span> +<span class="r-out co"><span class="r-pr">#></span> M1_sink 0.2771</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Estimated disappearance times:</span> +<span class="r-out co"><span class="r-pr">#></span> DT50 DT90</span> +<span class="r-out co"><span class="r-pr">#></span> parent 0.9376 3.114</span> +<span class="r-out co"><span class="r-pr">#></span> M1 2.3170 7.697</span> +<span class="r-out co"><span class="r-pr">#></span> M2 34.2689 113.839</span> +<span class="r-out co"><span class="r-pr">#></span> </span> +<span class="r-out co"><span class="r-pr">#></span> Data:</span> +<span class="r-out co"><span class="r-pr">#></span> time variable observed predicted residual</span> +<span class="r-out co"><span class="r-pr">#></span> 0 parent 101.5 1.021e+02 -0.56248</span> +<span class="r-out co"><span class="r-pr">#></span> 0 parent 101.2 1.021e+02 -0.86248</span> +<span class="r-out co"><span class="r-pr">#></span> 1 parent 53.9 4.873e+01 5.17118</span> +<span class="r-out co"><span class="r-pr">#></span> 1 parent 47.5 4.873e+01 -1.22882</span> +<span class="r-out co"><span class="r-pr">#></span> 3 parent 10.4 1.111e+01 -0.70773</span> +<span class="r-out co"><span class="r-pr">#></span> 3 parent 7.6 1.111e+01 -3.50773</span> +<span class="r-out co"><span class="r-pr">#></span> 7 parent 1.1 5.772e-01 0.52283</span> +<span class="r-out co"><span class="r-pr">#></span> 7 parent 0.3 5.772e-01 -0.27717</span> +<span class="r-out co"><span class="r-pr">#></span> 14 parent 3.5 3.264e-03 3.49674</span> +<span class="r-out co"><span class="r-pr">#></span> 28 parent 3.2 1.045e-07 3.20000</span> +<span class="r-out co"><span class="r-pr">#></span> 90 parent 0.6 9.530e-10 0.60000</span> +<span class="r-out co"><span class="r-pr">#></span> 120 parent 3.5 -5.940e-10 3.50000</span> +<span class="r-out co"><span class="r-pr">#></span> 1 M1 36.4 3.479e+01 1.61088</span> +<span class="r-out co"><span class="r-pr">#></span> 1 M1 37.4 3.479e+01 2.61088</span> +<span class="r-out co"><span class="r-pr">#></span> 3 M1 34.3 3.937e+01 -5.07027</span> +<span class="r-out co"><span class="r-pr">#></span> 3 M1 39.8 3.937e+01 0.42973</span> +<span class="r-out co"><span class="r-pr">#></span> 7 M1 15.1 1.549e+01 -0.38715</span> +<span class="r-out co"><span class="r-pr">#></span> 7 M1 17.8 1.549e+01 2.31285</span> +<span class="r-out co"><span class="r-pr">#></span> 14 M1 5.8 1.995e+00 3.80469</span> +<span class="r-out co"><span class="r-pr">#></span> 14 M1 1.2 1.995e+00 -0.79531</span> +<span class="r-out co"><span class="r-pr">#></span> 60 M1 0.5 2.111e-06 0.50000</span> +<span class="r-out co"><span class="r-pr">#></span> 90 M1 3.2 -9.670e-10 3.20000</span> +<span class="r-out co"><span class="r-pr">#></span> 120 M1 1.5 7.670e-10 1.50000</span> +<span class="r-out co"><span class="r-pr">#></span> 120 M1 0.6 7.670e-10 0.60000</span> +<span class="r-out co"><span class="r-pr">#></span> 1 M2 4.8 4.455e+00 0.34517</span> +<span class="r-out co"><span class="r-pr">#></span> 3 M2 20.9 2.153e+01 -0.62527</span> +<span class="r-out co"><span class="r-pr">#></span> 3 M2 19.3 2.153e+01 -2.22527</span> +<span class="r-out co"><span class="r-pr">#></span> 7 M2 42.0 4.192e+01 0.07941</span> +<span class="r-out co"><span class="r-pr">#></span> 7 M2 43.1 4.192e+01 1.17941</span> +<span class="r-out co"><span class="r-pr">#></span> 14 M2 49.4 4.557e+01 3.83353</span> +<span class="r-out co"><span class="r-pr">#></span> 14 M2 44.3 4.557e+01 -1.26647</span> +<span class="r-out co"><span class="r-pr">#></span> 28 M2 34.6 3.547e+01 -0.87275</span> +<span class="r-out co"><span class="r-pr">#></span> 28 M2 33.0 3.547e+01 -2.47275</span> +<span class="r-out co"><span class="r-pr">#></span> 60 M2 18.8 1.858e+01 0.21837</span> +<span class="r-out co"><span class="r-pr">#></span> 60 M2 17.6 1.858e+01 -0.98163</span> +<span class="r-out co"><span class="r-pr">#></span> 90 M2 10.6 1.013e+01 0.47130</span> +<span class="r-out co"><span class="r-pr">#></span> 90 M2 10.8 1.013e+01 0.67130</span> +<span class="r-out co"><span class="r-pr">#></span> 120 M2 9.8 5.521e+00 4.27893</span> +<span class="r-out co"><span class="r-pr">#></span> 120 M2 3.3 5.521e+00 -2.22107</span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/test_data_from_UBA_2014-1.png b/docs/reference/test_data_from_UBA_2014-1.png Binary files differindex 7bf0bd0f..e4fc2a4c 100644 --- a/docs/reference/test_data_from_UBA_2014-1.png +++ b/docs/reference/test_data_from_UBA_2014-1.png diff --git a/docs/reference/test_data_from_UBA_2014-2.png b/docs/reference/test_data_from_UBA_2014-2.png Binary files differindex fc1f77e0..4ce36561 100644 --- a/docs/reference/test_data_from_UBA_2014-2.png +++ b/docs/reference/test_data_from_UBA_2014-2.png diff --git a/docs/reference/test_data_from_UBA_2014.html b/docs/reference/test_data_from_UBA_2014.html index c0056d45..39b9becb 100644 --- a/docs/reference/test_data_from_UBA_2014.html +++ b/docs/reference/test_data_from_UBA_2014.html @@ -1,68 +1,13 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Three experimental datasets from two water sediment systems and one soil — test_data_from_UBA_2014 • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Three experimental datasets from two water sediment systems and one soil — test_data_from_UBA_2014" /> -<meta property="og:description" content="The datasets were used for the comparative validation of several kinetic evaluation - software packages (Ranke, 2014)." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Three experimental datasets from two water sediment systems and one soil — test_data_from_UBA_2014 • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Three experimental datasets from two water sediment systems and one soil — test_data_from_UBA_2014"><meta property="og:description" content="The datasets were used for the comparative validation of several kinetic evaluation + software packages (Ranke, 2014)."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -73,13 +18,12 @@ </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -88,8 +32,7 @@ <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -99,6 +42,9 @@ <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -113,30 +59,23 @@ <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Three experimental datasets from two water sediment systems and one soil</h1> @@ -149,113 +88,123 @@ software packages (Ranke, 2014).</p> </div> - <pre class="usage"><span class='va'>test_data_from_UBA_2014</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="va">test_data_from_UBA_2014</span></code></pre></div> + </div> + <div id="format"> + <h2>Format</h2> + <p>A list containing three datasets as an R6 class defined by <code><a href="mkinds.html">mkinds</a></code>. + Each dataset has, among others, the following components</p><dl><dt><code>title</code></dt> +<dd><p>The name of the dataset, e.g. <code>UBA_2014_WS_river</code></p></dd> - <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2> + <dt><code>data</code></dt> +<dd><p>A data frame with the data in the form expected by <code><a href="mkinfit.html">mkinfit</a></code></p></dd> - <p>A list containing three datasets as an R6 class defined by <code><a href='mkinds.html'>mkinds</a></code>. - Each dataset has, among others, the following components</p><dl> - <dt><code>title</code></dt><dd><p>The name of the dataset, e.g. <code>UBA_2014_WS_river</code></p></dd> - <dt><code>data</code></dt><dd><p>A data frame with the data in the form expected by <code><a href='mkinfit.html'>mkinfit</a></code></p></dd> -</dl> - - <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2> - +</dl></div> + <div id="source"> + <h2>Source</h2> <p>Ranke (2014) Prüfung und Validierung von Modellierungssoftware als Alternative zu ModelMaker 4.0, Umweltbundesamt Projektnummer 27452</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> <span class='co'># \dontrun{</span> - <span class='co'># This is a level P-II evaluation of the dataset according to the FOCUS kinetics</span> - <span class='co'># guidance. Due to the strong correlation of the parameter estimates, the</span> - <span class='co'># covariance matrix is not returned. Note that level P-II evaluations are</span> - <span class='co'># generally considered deprecated due to the frequent occurrence of such</span> - <span class='co'># large parameter correlations, among other reasons (e.g. the adequacy of the</span> - <span class='co'># model).</span> - <span class='va'>m_ws</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent_w <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"parent_s"</span><span class='op'>)</span>, - parent_s <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"parent_w"</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> <span class='va'>f_river</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>m_ws</span>, <span class='va'>test_data_from_UBA_2014</span><span class='op'>[[</span><span class='fl'>1</span><span class='op'>]</span><span class='op'>]</span><span class='op'>$</span><span class='va'>data</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='warning'>Warning: Observations with value of zero were removed from the data</span></div><div class='input'> <span class='fu'><a href='plot.mkinfit.html'>plot_sep</a></span><span class='op'>(</span><span class='va'>f_river</span><span class='op'>)</span> -</div><div class='img'><img src='test_data_from_UBA_2014-1.png' alt='' width='700' height='433' /></div><div class='input'> - <span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>f_river</span><span class='op'>)</span><span class='op'>$</span><span class='va'>bpar</span> -</div><div class='output co'>#> <span class='warning'>Warning: Could not calculate correlation; no covariance matrix</span></div><div class='output co'>#> Estimate se_notrans t value Pr(>t) Lower Upper -#> parent_w_0 95.91998118 NA NA NA NA NA -#> k_parent_w 0.41145375 NA NA NA NA NA -#> k_parent_s 0.04663944 NA NA NA NA NA -#> f_parent_w_to_parent_s 0.12467894 NA NA NA NA NA -#> f_parent_s_to_parent_w 0.50000000 NA NA NA NA NA -#> sigma 3.13612618 NA NA NA NA NA</div><div class='input'> <span class='fu'><a href='mkinerrmin.html'>mkinerrmin</a></span><span class='op'>(</span><span class='va'>f_river</span><span class='op'>)</span> -</div><div class='output co'>#> err.min n.optim df -#> All data 0.1090929 5 6 -#> parent_w 0.0817436 3 3 -#> parent_s 0.1619965 2 3</div><div class='input'> - <span class='co'># This is the evaluation used for the validation of software packages</span> - <span class='co'># in the expertise from 2014</span> - <span class='va'>m_soil</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span>parent <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"M1"</span>, <span class='st'>"M2"</span><span class='op'>)</span><span class='op'>)</span>, - M1 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"M3"</span><span class='op'>)</span>, - M2 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='st'>"M3"</span><span class='op'>)</span>, - M3 <span class='op'>=</span> <span class='fu'><a href='mkinmod.html'>mkinsub</a></span><span class='op'>(</span><span class='st'>"SFO"</span><span class='op'>)</span>, - use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> - <span class='va'>f_soil</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>m_soil</span>, <span class='va'>test_data_from_UBA_2014</span><span class='op'>[[</span><span class='fl'>3</span><span class='op'>]</span><span class='op'>]</span><span class='op'>$</span><span class='va'>data</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='warning'>Warning: Observations with value of zero were removed from the data</span></div><div class='input'> <span class='fu'><a href='plot.mkinfit.html'>plot_sep</a></span><span class='op'>(</span><span class='va'>f_soil</span>, lpos <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"topright"</span>, <span class='st'>"topright"</span>, <span class='st'>"topright"</span>, <span class='st'>"bottomright"</span><span class='op'>)</span><span class='op'>)</span> -</div><div class='img'><img src='test_data_from_UBA_2014-2.png' alt='' width='700' height='433' /></div><div class='input'> <span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>f_soil</span><span class='op'>)</span><span class='op'>$</span><span class='va'>bpar</span> -</div><div class='output co'>#> Estimate se_notrans t value Pr(>t) Lower -#> parent_0 76.55425650 0.859186399 89.1008710 1.113861e-26 74.755959418 -#> k_parent 0.12081956 0.004601918 26.2541722 1.077359e-16 0.111561575 -#> k_M1 0.84258615 0.806160102 1.0451846 1.545268e-01 0.113779609 -#> k_M2 0.04210880 0.017083034 2.4649483 1.170188e-02 0.018013857 -#> k_M3 0.01122918 0.007245856 1.5497385 6.885052e-02 0.002909431 -#> f_parent_to_M1 0.32240200 0.240783943 1.3389680 9.819076e-02 NA -#> f_parent_to_M2 0.16099855 0.033691952 4.7785464 6.531136e-05 NA -#> f_M1_to_M3 0.27921507 0.269423780 1.0363416 1.565267e-01 0.022978205 -#> f_M2_to_M3 0.55641252 0.595119966 0.9349586 1.807707e-01 0.008002509 -#> sigma 1.14005399 0.149696423 7.6157731 1.727024e-07 0.826735778 -#> Upper -#> parent_0 78.35255358 -#> k_parent 0.13084582 -#> k_M1 6.23970702 -#> k_M2 0.09843260 -#> k_M3 0.04333992 -#> f_parent_to_M1 NA -#> f_parent_to_M2 NA -#> f_M1_to_M3 0.86450775 -#> f_M2_to_M3 0.99489895 -#> sigma 1.45337221</div><div class='input'> <span class='fu'><a href='mkinerrmin.html'>mkinerrmin</a></span><span class='op'>(</span><span class='va'>f_soil</span><span class='op'>)</span> -</div><div class='output co'>#> err.min n.optim df -#> All data 0.09649963 9 20 -#> parent 0.04721283 2 6 -#> M1 0.26551208 2 5 -#> M2 0.20327575 2 5 -#> M3 0.05196550 3 4</div><div class='input'> <span class='co'># }</span> -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"> <span class="co"># \dontrun{</span></span> +<span class="r-in"> <span class="co"># This is a level P-II evaluation of the dataset according to the FOCUS kinetics</span></span> +<span class="r-in"> <span class="co"># guidance. Due to the strong correlation of the parameter estimates, the</span></span> +<span class="r-in"> <span class="co"># covariance matrix is not returned. Note that level P-II evaluations are</span></span> +<span class="r-in"> <span class="co"># generally considered deprecated due to the frequent occurrence of such</span></span> +<span class="r-in"> <span class="co"># large parameter correlations, among other reasons (e.g. the adequacy of the</span></span> +<span class="r-in"> <span class="co"># model).</span></span> +<span class="r-in"> <span class="va">m_ws</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent_w <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"parent_s"</span><span class="op">)</span>,</span> +<span class="r-in"> parent_s <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"parent_w"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"> <span class="va">f_river</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">m_ws</span>, <span class="va">test_data_from_UBA_2014</span><span class="op">[[</span><span class="fl">1</span><span class="op">]</span><span class="op">]</span><span class="op">$</span><span class="va">data</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="plot.mkinfit.html">plot_sep</a></span><span class="op">(</span><span class="va">f_river</span><span class="op">)</span></span> +<span class="r-plt img"><img src="test_data_from_UBA_2014-1.png" alt="" width="700" height="433"></span> +<span class="r-in"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/pkg/saemix/man/summary-methods.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">f_river</span><span class="op">)</span><span class="op">$</span><span class="va">bpar</span></span> +<span class="r-out co"><span class="r-pr">#></span> Estimate se_notrans t value Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_w_0 95.91998118 NA NA NA NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_w 0.41145375 NA NA NA NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_s 0.04663944 NA NA NA NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_w_to_parent_s 0.12467894 NA NA NA NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_s_to_parent_w 0.50000000 NA NA NA NA NA</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 3.13612618 NA NA NA NA NA</span> +<span class="r-in"> <span class="fu"><a href="mkinerrmin.html">mkinerrmin</a></span><span class="op">(</span><span class="va">f_river</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> err.min n.optim df</span> +<span class="r-out co"><span class="r-pr">#></span> All data 0.1090929 5 6</span> +<span class="r-out co"><span class="r-pr">#></span> parent_w 0.0817436 3 3</span> +<span class="r-out co"><span class="r-pr">#></span> parent_s 0.1619965 2 3</span> +<span class="r-in"></span> +<span class="r-in"> <span class="co"># This is the evaluation used for the validation of software packages</span></span> +<span class="r-in"> <span class="co"># in the expertise from 2014</span></span> +<span class="r-in"> <span class="va">m_soil</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span>parent <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"M1"</span>, <span class="st">"M2"</span><span class="op">)</span><span class="op">)</span>,</span> +<span class="r-in"> M1 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"M3"</span><span class="op">)</span>,</span> +<span class="r-in"> M2 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="st">"M3"</span><span class="op">)</span>,</span> +<span class="r-in"> M3 <span class="op">=</span> <span class="fu"><a href="mkinmod.html">mkinsub</a></span><span class="op">(</span><span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"> <span class="va">f_soil</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">m_soil</span>, <span class="va">test_data_from_UBA_2014</span><span class="op">[[</span><span class="fl">3</span><span class="op">]</span><span class="op">]</span><span class="op">$</span><span class="va">data</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"> <span class="fu"><a href="plot.mkinfit.html">plot_sep</a></span><span class="op">(</span><span class="va">f_soil</span>, lpos <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"topright"</span>, <span class="st">"topright"</span>, <span class="st">"topright"</span>, <span class="st">"bottomright"</span><span class="op">)</span><span class="op">)</span></span> +<span class="r-plt img"><img src="test_data_from_UBA_2014-2.png" alt="" width="700" height="433"></span> +<span class="r-in"> <span class="fu"><a href="https://rdrr.io/pkg/saemix/man/summary-methods.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">f_soil</span><span class="op">)</span><span class="op">$</span><span class="va">bpar</span></span> +<span class="r-out co"><span class="r-pr">#></span> Estimate se_notrans t value Pr(>t) Lower</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 76.55425650 0.859186399 89.1008710 1.113861e-26 74.755959418</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.12081956 0.004601918 26.2541722 1.077359e-16 0.111561575</span> +<span class="r-out co"><span class="r-pr">#></span> k_M1 0.84258615 0.806160102 1.0451846 1.545268e-01 0.113779609</span> +<span class="r-out co"><span class="r-pr">#></span> k_M2 0.04210880 0.017083034 2.4649483 1.170188e-02 0.018013857</span> +<span class="r-out co"><span class="r-pr">#></span> k_M3 0.01122918 0.007245856 1.5497385 6.885052e-02 0.002909431</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_M1 0.32240200 0.240783943 1.3389680 9.819076e-02 NA</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_M2 0.16099855 0.033691952 4.7785464 6.531136e-05 NA</span> +<span class="r-out co"><span class="r-pr">#></span> f_M1_to_M3 0.27921507 0.269423780 1.0363416 1.565267e-01 0.022978205</span> +<span class="r-out co"><span class="r-pr">#></span> f_M2_to_M3 0.55641252 0.595119966 0.9349586 1.807707e-01 0.008002509</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 1.14005399 0.149696423 7.6157731 1.727024e-07 0.826735778</span> +<span class="r-out co"><span class="r-pr">#></span> Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 78.35255358</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.13084582</span> +<span class="r-out co"><span class="r-pr">#></span> k_M1 6.23970702</span> +<span class="r-out co"><span class="r-pr">#></span> k_M2 0.09843260</span> +<span class="r-out co"><span class="r-pr">#></span> k_M3 0.04333992</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_M1 NA</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_M2 NA</span> +<span class="r-out co"><span class="r-pr">#></span> f_M1_to_M3 0.86450775</span> +<span class="r-out co"><span class="r-pr">#></span> f_M2_to_M3 0.99489895</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 1.45337221</span> +<span class="r-in"> <span class="fu"><a href="mkinerrmin.html">mkinerrmin</a></span><span class="op">(</span><span class="va">f_soil</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> err.min n.optim df</span> +<span class="r-out co"><span class="r-pr">#></span> All data 0.09649963 9 20</span> +<span class="r-out co"><span class="r-pr">#></span> parent 0.04721283 2 6</span> +<span class="r-out co"><span class="r-pr">#></span> M1 0.26551208 2 5</span> +<span class="r-out co"><span class="r-pr">#></span> M2 0.20327575 2 5</span> +<span class="r-out co"><span class="r-pr">#></span> M3 0.05196550 3 4</span> +<span class="r-in"> <span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/tffm0.html b/docs/reference/tffm0.html new file mode 100644 index 00000000..bc033fb3 --- /dev/null +++ b/docs/reference/tffm0.html @@ -0,0 +1,165 @@ +<!DOCTYPE html> +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Transform formation fractions as in the first published mkin version — tffm0 • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Transform formation fractions as in the first published mkin version — tffm0"><meta property="og:description" content="This transformation was used originally in mkin, in order to implement a +constraint for the sum of formation fractions to be smaller than 1. It was +later replaced by the ilr transformation because the ilr transformed +fractions can assumed to follow normal distribution. As the ilr +transformation is not available in RxODE and can therefore not be used in +the nlmixr modelling language, the original transformation is currently used +for translating mkin models with formation fractions to more than one target +compartment for fitting with nlmixr in nlmixr_model. However, this +implementation cannot be used there, as it is not accessible from RxODE."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> +<script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> +<script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + + + <div class="container template-reference-topic"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <div class="container"> + <div class="navbar-header"> + <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> + <span class="sr-only">Toggle navigation</span> + <span class="icon-bar"></span> + <span class="icon-bar"></span> + <span class="icon-bar"></span> + </button> + <span class="navbar-brand"> + <a class="navbar-link" href="../index.html">mkin</a> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> + </span> + </div> + + <div id="navbar" class="navbar-collapse collapse"> + <ul class="nav navbar-nav"><li> + <a href="../reference/index.html">Functions and data</a> +</li> +<li class="dropdown"> + <a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-expanded="false"> + Articles + + <span class="caret"></span> + </a> + <ul class="dropdown-menu" role="menu"><li> + <a href="../articles/mkin.html">Introduction to mkin</a> + </li> + <li> + <a href="../articles/FOCUS_D.html">Example evaluation of FOCUS Example Dataset D</a> + </li> + <li> + <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> + </li> + <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> + <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> + </li> + <li> + <a href="../articles/web_only/compiled_models.html">Performance benefit by using compiled model definitions in mkin</a> + </li> + <li> + <a href="../articles/twa.html">Calculation of time weighted average concentrations with mkin</a> + </li> + <li> + <a href="../articles/web_only/NAFTA_examples.html">Example evaluation of NAFTA SOP Attachment examples</a> + </li> + <li> + <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> + </li> + </ul></li> +<li> + <a href="../news/index.html">News</a> +</li> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> + <span class="fab fa-github fa-lg"></span> + + </a> +</li> + </ul></div><!--/.nav-collapse --> + </div><!--/.container --> +</div><!--/.navbar --> + + + + </header><div class="row"> + <div class="col-md-9 contents"> + <div class="page-header"> + <h1>Transform formation fractions as in the first published mkin version</h1> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/tffm0.R" class="external-link"><code>R/tffm0.R</code></a></small> + <div class="hidden name"><code>tffm0.Rd</code></div> + </div> + + <div class="ref-description"> + <p>This transformation was used originally in mkin, in order to implement a +constraint for the sum of formation fractions to be smaller than 1. It was +later replaced by the <a href="ilr.html">ilr</a> transformation because the ilr transformed +fractions can assumed to follow normal distribution. As the ilr +transformation is not available in <a href="https://nlmixrdevelopment.github.io/RxODE/reference/RxODE.html" class="external-link">RxODE</a> and can therefore not be used in +the nlmixr modelling language, the original transformation is currently used +for translating mkin models with formation fractions to more than one target +compartment for fitting with nlmixr in <a href="nlmixr.mmkin.html">nlmixr_model</a>. However, this +implementation cannot be used there, as it is not accessible from RxODE.</p> + </div> + + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">tffm0</span><span class="op">(</span><span class="va">ff</span><span class="op">)</span> + +<span class="fu">invtffm0</span><span class="op">(</span><span class="va">ff_trans</span><span class="op">)</span></code></pre></div> + </div> + + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>ff</dt> +<dd><p>Vector of untransformed formation fractions. The sum +must be smaller or equal to one</p></dd> +<dt>ff_trans</dt> +<dd><p>Vector of transformed formation fractions that can be +restricted to the interval from 0 to 1</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> + <p>A vector of the transformed formation fractions +A vector of backtransformed formation fractions for natural use in degradation models</p> + </div> + <div id="details"> + <h2>Details</h2> + <p>If the transformed formation fractions are restricted to the interval +between 0 and 1, the sum of backtransformed values is restricted +to this interval.</p> + </div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="va">ff_example</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span></span> +<span class="r-in"> <span class="fl">0.10983681</span>, <span class="fl">0.09035905</span>, <span class="fl">0.08399383</span></span> +<span class="r-in"><span class="op">)</span></span> +<span class="r-in"><span class="va">ff_example_trans</span> <span class="op"><-</span> <span class="fu">tffm0</span><span class="op">(</span><span class="va">ff_example</span><span class="op">)</span></span> +<span class="r-in"><span class="fu">invtffm0</span><span class="op">(</span><span class="va">ff_example_trans</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> [1] 0.10983681 0.09035905 0.08399383</span> +</code></pre></div> + </div> + </div> + <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> +</div> + + + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> +</div> + +<div class="pkgdown"> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> +</div> + + </footer></div> + + + + + + + </body></html> + diff --git a/docs/reference/transform_odeparms.html b/docs/reference/transform_odeparms.html index bbaad91e..25d0e76b 100644 --- a/docs/reference/transform_odeparms.html +++ b/docs/reference/transform_odeparms.html @@ -1,72 +1,17 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Functions to transform and backtransform kinetic parameters for fitting — transform_odeparms • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Functions to transform and backtransform kinetic parameters for fitting — transform_odeparms" /> -<meta property="og:description" content="The transformations are intended to map parameters that should only take on +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Functions to transform and backtransform kinetic parameters for fitting — transform_odeparms • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Functions to transform and backtransform kinetic parameters for fitting — transform_odeparms"><meta property="og:description" content="The transformations are intended to map parameters that should only take on restricted values to the full scale of real numbers. For kinetic rate constants and other parameters that can only take on positive values, a simple log transformation is used. For compositional parameters, such as the formations fractions that should always sum up to 1 and can not be negative, -the ilr transformation is used." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +the ilr transformation is used."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - - - </head> +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -77,13 +22,12 @@ the ilr transformation is used." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.4</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -92,8 +36,7 @@ the ilr transformation is used." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -103,6 +46,9 @@ the ilr transformation is used." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -117,34 +63,27 @@ the ilr transformation is used." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Functions to transform and backtransform kinetic parameters for fitting</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/transform_odeparms.R'><code>R/transform_odeparms.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/transform_odeparms.R" class="external-link"><code>R/transform_odeparms.R</code></a></small> <div class="hidden name"><code>transform_odeparms.Rd</code></div> </div> @@ -154,205 +93,210 @@ restricted values to the full scale of real numbers. For kinetic rate constants and other parameters that can only take on positive values, a simple log transformation is used. For compositional parameters, such as the formations fractions that should always sum up to 1 and can not be negative, -the <a href='ilr.html'>ilr</a> transformation is used.</p> +the <a href="ilr.html">ilr</a> transformation is used.</p> </div> - <pre class="usage"><span class='fu'>transform_odeparms</span><span class='op'>(</span> - <span class='va'>parms</span>, - <span class='va'>mkinmod</span>, - transform_rates <span class='op'>=</span> <span class='cn'>TRUE</span>, - transform_fractions <span class='op'>=</span> <span class='cn'>TRUE</span> -<span class='op'>)</span> - -<span class='fu'>backtransform_odeparms</span><span class='op'>(</span> - <span class='va'>transparms</span>, - <span class='va'>mkinmod</span>, - transform_rates <span class='op'>=</span> <span class='cn'>TRUE</span>, - transform_fractions <span class='op'>=</span> <span class='cn'>TRUE</span> -<span class='op'>)</span></pre> + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="fu">transform_odeparms</span><span class="op">(</span> + <span class="va">parms</span>, + <span class="va">mkinmod</span>, + transform_rates <span class="op">=</span> <span class="cn">TRUE</span>, + transform_fractions <span class="op">=</span> <span class="cn">TRUE</span> +<span class="op">)</span> + +<span class="fu">backtransform_odeparms</span><span class="op">(</span> + <span class="va">transparms</span>, + <span class="va">mkinmod</span>, + transform_rates <span class="op">=</span> <span class="cn">TRUE</span>, + transform_fractions <span class="op">=</span> <span class="cn">TRUE</span> +<span class="op">)</span></code></pre></div> + </div> - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>parms</th> - <td><p>Parameters of kinetic models as used in the differential -equations.</p></td> - </tr> - <tr> - <th>mkinmod</th> - <td><p>The kinetic model of class <a href='mkinmod.html'>mkinmod</a>, containing + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>parms</dt> +<dd><p>Parameters of kinetic models as used in the differential +equations.</p></dd> +<dt>mkinmod</dt> +<dd><p>The kinetic model of class <a href="mkinmod.html">mkinmod</a>, containing the names of the model variables that are needed for grouping the -formation fractions before <a href='ilr.html'>ilr</a> transformation, the parameter -names and the information if the pathway to sink is included in the model.</p></td> - </tr> - <tr> - <th>transform_rates</th> - <td><p>Boolean specifying if kinetic rate constants should +formation fractions before <a href="ilr.html">ilr</a> transformation, the parameter +names and the information if the pathway to sink is included in the model.</p></dd> +<dt>transform_rates</dt> +<dd><p>Boolean specifying if kinetic rate constants should be transformed in the model specification used in the fitting for better compliance with the assumption of normal distribution of the estimator. If TRUE, also alpha and beta parameters of the FOMC model are log-transformed, as well as k1 and k2 rate constants for the DFOP and HS -models and the break point tb of the HS model.</p></td> - </tr> - <tr> - <th>transform_fractions</th> - <td><p>Boolean specifying if formation fractions +models and the break point tb of the HS model.</p></dd> +<dt>transform_fractions</dt> +<dd><p>Boolean specifying if formation fractions constants should be transformed in the model specification used in the fitting for better compliance with the assumption of normal distribution of the estimator. The default (TRUE) is to do transformations. The g parameter of the DFOP model is also seen as a fraction. If a single fraction is transformed (g parameter of DFOP or only a single target variable e.g. a single metabolite plus a pathway to sink), a -logistic transformation is used <code><a href='https://rdrr.io/r/stats/Logistic.html'>stats::qlogis()</a></code>. In other cases, i.e. if +logistic transformation is used <code><a href="https://rdrr.io/r/stats/Logistic.html" class="external-link">stats::qlogis()</a></code>. In other cases, i.e. if two or more formation fractions need to be transformed whose sum cannot -exceed one, the <a href='ilr.html'>ilr</a> transformation is used.</p></td> - </tr> - <tr> - <th>transparms</th> - <td><p>Transformed parameters of kinetic models as used in the -fitting procedure.</p></td> - </tr> - </table> - - <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2> - +exceed one, the <a href="ilr.html">ilr</a> transformation is used.</p></dd> +<dt>transparms</dt> +<dd><p>Transformed parameters of kinetic models as used in the +fitting procedure.</p></dd> +</dl></div> + <div id="value"> + <h2>Value</h2> <p>A vector of transformed or backtransformed parameters</p> - <h2 class="hasAnchor" id="details"><a class="anchor" href="#details"></a>Details</h2> - + </div> + <div id="details"> + <h2>Details</h2> <p>The transformation of sets of formation fractions is fragile, as it supposes the same ordering of the components in forward and backward transformation. -This is no problem for the internal use in <a href='mkinfit.html'>mkinfit</a>.</p> - <h2 class="hasAnchor" id="author"><a class="anchor" href="#author"></a>Author</h2> - +This is no problem for the internal use in <a href="mkinfit.html">mkinfit</a>.</p> + </div> + <div id="author"> + <h2>Author</h2> <p>Johannes Ranke</p> + </div> - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'> -<span class='va'>SFO_SFO</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"m1"</span>, sink <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span>, - m1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, use_of_ff <span class='op'>=</span> <span class='st'>"min"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> -<span class='co'># Fit the model to the FOCUS example dataset D using defaults</span> -<span class='va'>FOCUS_D</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/subset.html'>subset</a></span><span class='op'>(</span><span class='va'>FOCUS_2006_D</span>, <span class='va'>value</span> <span class='op'>!=</span> <span class='fl'>0</span><span class='op'>)</span> <span class='co'># remove zero values to avoid warning</span> -<span class='va'>fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='va'>fit.s</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span> -<span class='co'># Transformed and backtransformed parameters</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>fit.s</span><span class='op'>$</span><span class='va'>par</span>, <span class='fl'>3</span><span class='op'>)</span> -</div><div class='output co'>#> Estimate Std. Error Lower Upper -#> parent_0 99.60 1.5702 96.40 102.79 -#> log_k_parent_sink -3.04 0.0763 -3.19 -2.88 -#> log_k_parent_m1 -2.98 0.0403 -3.06 -2.90 -#> log_k_m1_sink -5.25 0.1332 -5.52 -4.98 -#> sigma 3.13 0.3585 2.40 3.85</div><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>fit.s</span><span class='op'>$</span><span class='va'>bpar</span>, <span class='fl'>3</span><span class='op'>)</span> -</div><div class='output co'>#> Estimate se_notrans t value Pr(>t) Lower Upper -#> parent_0 99.59848 1.57022 63.43 2.30e-36 96.40384 102.7931 -#> k_parent_sink 0.04792 0.00365 13.11 6.13e-15 0.04103 0.0560 -#> k_parent_m1 0.05078 0.00205 24.80 3.27e-23 0.04678 0.0551 -#> k_m1_sink 0.00526 0.00070 7.51 6.16e-09 0.00401 0.0069 -#> sigma 3.12550 0.35852 8.72 2.24e-10 2.39609 3.8549</div><div class='input'> -<span class='co'># \dontrun{</span> -<span class='co'># Compare to the version without transforming rate parameters (does not work</span> -<span class='co'># with analytical solution, we get NA values for m1 in predictions)</span> -<span class='va'>fit.2</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO</span>, <span class='va'>FOCUS_D</span>, transform_rates <span class='op'>=</span> <span class='cn'>FALSE</span>, - solution_type <span class='op'>=</span> <span class='st'>"deSolve"</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='va'>fit.2.s</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>fit.2</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>fit.2.s</span><span class='op'>$</span><span class='va'>par</span>, <span class='fl'>3</span><span class='op'>)</span> -</div><div class='output co'>#> Estimate Std. Error Lower Upper -#> parent_0 99.59848 1.57022 96.40384 1.03e+02 -#> k_parent_sink 0.04792 0.00365 0.04049 5.54e-02 -#> k_parent_m1 0.05078 0.00205 0.04661 5.49e-02 -#> k_m1_sink 0.00526 0.00070 0.00384 6.69e-03 -#> sigma 3.12550 0.35852 2.39609 3.85e+00</div><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>fit.2.s</span><span class='op'>$</span><span class='va'>bpar</span>, <span class='fl'>3</span><span class='op'>)</span> -</div><div class='output co'>#> Estimate se_notrans t value Pr(>t) Lower Upper -#> parent_0 99.59848 1.57022 63.43 2.30e-36 96.40384 1.03e+02 -#> k_parent_sink 0.04792 0.00365 13.11 6.13e-15 0.04049 5.54e-02 -#> k_parent_m1 0.05078 0.00205 24.80 3.27e-23 0.04661 5.49e-02 -#> k_m1_sink 0.00526 0.00070 7.51 6.16e-09 0.00384 6.69e-03 -#> sigma 3.12550 0.35852 8.72 2.24e-10 2.39609 3.85e+00</div><div class='input'><span class='co'># }</span> - -<span class='va'>initials</span> <span class='op'><-</span> <span class='va'>fit</span><span class='op'>$</span><span class='va'>start</span><span class='op'>$</span><span class='va'>value</span> -<span class='fu'><a href='https://rdrr.io/r/base/names.html'>names</a></span><span class='op'>(</span><span class='va'>initials</span><span class='op'>)</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/colnames.html'>rownames</a></span><span class='op'>(</span><span class='va'>fit</span><span class='op'>$</span><span class='va'>start</span><span class='op'>)</span> -<span class='va'>transformed</span> <span class='op'><-</span> <span class='va'>fit</span><span class='op'>$</span><span class='va'>start_transformed</span><span class='op'>$</span><span class='va'>value</span> -<span class='fu'><a href='https://rdrr.io/r/base/names.html'>names</a></span><span class='op'>(</span><span class='va'>transformed</span><span class='op'>)</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/colnames.html'>rownames</a></span><span class='op'>(</span><span class='va'>fit</span><span class='op'>$</span><span class='va'>start_transformed</span><span class='op'>)</span> -<span class='fu'>transform_odeparms</span><span class='op'>(</span><span class='va'>initials</span>, <span class='va'>SFO_SFO</span><span class='op'>)</span> -</div><div class='output co'>#> parent_0 log_k_parent_sink log_k_parent_m1 log_k_m1_sink -#> 100.750000 -2.302585 -2.301586 -2.300587 </div><div class='input'><span class='fu'>backtransform_odeparms</span><span class='op'>(</span><span class='va'>transformed</span>, <span class='va'>SFO_SFO</span><span class='op'>)</span> -</div><div class='output co'>#> parent_0 k_parent_sink k_parent_m1 k_m1_sink -#> 100.7500 0.1000 0.1001 0.1002 </div><div class='input'> -<span class='co'># \dontrun{</span> -<span class='co'># The case of formation fractions (this is now the default)</span> -<span class='va'>SFO_SFO.ff</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"m1"</span>, sink <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span>, - m1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, - use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> -<span class='va'>fit.ff</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO.ff</span>, <span class='va'>FOCUS_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='va'>fit.ff.s</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>fit.ff</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>fit.ff.s</span><span class='op'>$</span><span class='va'>par</span>, <span class='fl'>3</span><span class='op'>)</span> -</div><div class='output co'>#> Estimate Std. Error Lower Upper -#> parent_0 99.5985 1.5702 96.404 102.79 -#> log_k_parent -2.3157 0.0409 -2.399 -2.23 -#> log_k_m1 -5.2475 0.1332 -5.518 -4.98 -#> f_parent_qlogis 0.0579 0.0893 -0.124 0.24 -#> sigma 3.1255 0.3585 2.396 3.85</div><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>fit.ff.s</span><span class='op'>$</span><span class='va'>bpar</span>, <span class='fl'>3</span><span class='op'>)</span> -</div><div class='output co'>#> Estimate se_notrans t value Pr(>t) Lower Upper -#> parent_0 99.59848 1.57022 63.43 2.30e-36 96.40383 102.7931 -#> k_parent 0.09870 0.00403 24.47 4.96e-23 0.09082 0.1073 -#> k_m1 0.00526 0.00070 7.51 6.16e-09 0.00401 0.0069 -#> f_parent_to_m1 0.51448 0.02230 23.07 3.10e-22 0.46912 0.5596 -#> sigma 3.12550 0.35852 8.72 2.24e-10 2.39609 3.8549</div><div class='input'><span class='va'>initials</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span><span class='op'>(</span><span class='st'>"f_parent_to_m1"</span> <span class='op'>=</span> <span class='fl'>0.5</span><span class='op'>)</span> -<span class='va'>transformed</span> <span class='op'><-</span> <span class='fu'>transform_odeparms</span><span class='op'>(</span><span class='va'>initials</span>, <span class='va'>SFO_SFO.ff</span><span class='op'>)</span> -<span class='fu'>backtransform_odeparms</span><span class='op'>(</span><span class='va'>transformed</span>, <span class='va'>SFO_SFO.ff</span><span class='op'>)</span> -</div><div class='output co'>#> f_parent_to_m1 -#> 0.5 </div><div class='input'> -<span class='co'># And without sink</span> -<span class='va'>SFO_SFO.ff.2</span> <span class='op'><-</span> <span class='fu'><a href='mkinmod.html'>mkinmod</a></span><span class='op'>(</span> - parent <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span>, to <span class='op'>=</span> <span class='st'>"m1"</span>, sink <span class='op'>=</span> <span class='cn'>FALSE</span><span class='op'>)</span>, - m1 <span class='op'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/list.html'>list</a></span><span class='op'>(</span>type <span class='op'>=</span> <span class='st'>"SFO"</span><span class='op'>)</span>, - use_of_ff <span class='op'>=</span> <span class='st'>"max"</span><span class='op'>)</span> -</div><div class='output co'>#> <span class='message'>Temporary DLL for differentials generated and loaded</span></div><div class='input'> - -<span class='va'>fit.ff.2</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='va'>SFO_SFO.ff.2</span>, <span class='va'>FOCUS_D</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='va'>fit.ff.2.s</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/base/summary.html'>summary</a></span><span class='op'>(</span><span class='va'>fit.ff.2</span><span class='op'>)</span> -<span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>fit.ff.2.s</span><span class='op'>$</span><span class='va'>par</span>, <span class='fl'>3</span><span class='op'>)</span> -</div><div class='output co'>#> Estimate Std. Error Lower Upper -#> parent_0 84.79 3.012 78.67 90.91 -#> log_k_parent -2.76 0.082 -2.92 -2.59 -#> log_k_m1 -4.21 0.123 -4.46 -3.96 -#> sigma 8.22 0.943 6.31 10.14</div><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span><span class='op'>(</span><span class='va'>fit.ff.2.s</span><span class='op'>$</span><span class='va'>bpar</span>, <span class='fl'>3</span><span class='op'>)</span> -</div><div class='output co'>#> Estimate se_notrans t value Pr(>t) Lower Upper -#> parent_0 84.7916 3.01203 28.15 1.92e-25 78.6704 90.913 -#> k_parent 0.0635 0.00521 12.19 2.91e-14 0.0538 0.075 -#> k_m1 0.0148 0.00182 8.13 8.81e-10 0.0115 0.019 -#> sigma 8.2229 0.94323 8.72 1.73e-10 6.3060 10.140</div><div class='input'><span class='co'># }</span> - -</div></pre> + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"></span> +<span class="r-in"><span class="va">SFO_SFO</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"m1"</span>, sink <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>, use_of_ff <span class="op">=</span> <span class="st">"min"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># Fit the model to the FOCUS example dataset D using defaults</span></span> +<span class="r-in"><span class="va">FOCUS_D</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/saemix/man/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">FOCUS_2006_D</span>, <span class="va">value</span> <span class="op">!=</span> <span class="fl">0</span><span class="op">)</span> <span class="co"># remove zero values to avoid warning</span></span> +<span class="r-in"><span class="va">fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">fit.s</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/saemix/man/summary-methods.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></span> +<span class="r-in"><span class="co"># Transformed and backtransformed parameters</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">fit.s</span><span class="op">$</span><span class="va">par</span>, <span class="fl">3</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Std. Error Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 99.60 1.5702 96.40 102.79</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent_sink -3.04 0.0763 -3.19 -2.88</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent_m1 -2.98 0.0403 -3.06 -2.90</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_m1_sink -5.25 0.1332 -5.52 -4.98</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 3.13 0.3585 2.40 3.85</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">fit.s</span><span class="op">$</span><span class="va">bpar</span>, <span class="fl">3</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Estimate se_notrans t value Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 99.59848 1.57022 63.43 2.30e-36 96.40384 102.7931</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_sink 0.04792 0.00365 13.11 6.13e-15 0.04103 0.0560</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_m1 0.05078 0.00205 24.80 3.27e-23 0.04678 0.0551</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1_sink 0.00526 0.00070 7.51 6.16e-09 0.00401 0.0069</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 3.12550 0.35852 8.72 2.24e-10 2.39609 3.8549</span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="co"># Compare to the version without transforming rate parameters (does not work</span></span> +<span class="r-in"><span class="co"># with analytical solution, we get NA values for m1 in predictions)</span></span> +<span class="r-in"><span class="va">fit.2</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO</span>, <span class="va">FOCUS_D</span>, transform_rates <span class="op">=</span> <span class="cn">FALSE</span>,</span> +<span class="r-in"> solution_type <span class="op">=</span> <span class="st">"deSolve"</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">fit.2.s</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/saemix/man/summary-methods.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">fit.2</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">fit.2.s</span><span class="op">$</span><span class="va">par</span>, <span class="fl">3</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Std. Error Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 99.59848 1.57022 96.40384 1.03e+02</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_sink 0.04792 0.00365 0.04049 5.54e-02</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_m1 0.05078 0.00205 0.04661 5.49e-02</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1_sink 0.00526 0.00070 0.00384 6.69e-03</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 3.12550 0.35852 2.39609 3.85e+00</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">fit.2.s</span><span class="op">$</span><span class="va">bpar</span>, <span class="fl">3</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Estimate se_notrans t value Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 99.59848 1.57022 63.43 2.30e-36 96.40384 1.03e+02</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_sink 0.04792 0.00365 13.11 6.13e-15 0.04049 5.54e-02</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent_m1 0.05078 0.00205 24.80 3.27e-23 0.04661 5.49e-02</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1_sink 0.00526 0.00070 7.51 6.16e-09 0.00384 6.69e-03</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 3.12550 0.35852 8.72 2.24e-10 2.39609 3.85e+00</span> +<span class="r-in"><span class="co"># }</span></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">initials</span> <span class="op"><-</span> <span class="va">fit</span><span class="op">$</span><span class="va">start</span><span class="op">$</span><span class="va">value</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">initials</span><span class="op">)</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/colnames.html" class="external-link">rownames</a></span><span class="op">(</span><span class="va">fit</span><span class="op">$</span><span class="va">start</span><span class="op">)</span></span> +<span class="r-in"><span class="va">transformed</span> <span class="op"><-</span> <span class="va">fit</span><span class="op">$</span><span class="va">start_transformed</span><span class="op">$</span><span class="va">value</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">transformed</span><span class="op">)</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/colnames.html" class="external-link">rownames</a></span><span class="op">(</span><span class="va">fit</span><span class="op">$</span><span class="va">start_transformed</span><span class="op">)</span></span> +<span class="r-in"><span class="fu">transform_odeparms</span><span class="op">(</span><span class="va">initials</span>, <span class="va">SFO_SFO</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 log_k_parent_sink log_k_parent_m1 log_k_m1_sink </span> +<span class="r-out co"><span class="r-pr">#></span> 100.750000 -2.302585 -2.301586 -2.300587 </span> +<span class="r-in"><span class="fu">backtransform_odeparms</span><span class="op">(</span><span class="va">transformed</span>, <span class="va">SFO_SFO</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 k_parent_sink k_parent_m1 k_m1_sink </span> +<span class="r-out co"><span class="r-pr">#></span> 100.7500 0.1000 0.1001 0.1002 </span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="co"># The case of formation fractions (this is now the default)</span></span> +<span class="r-in"><span class="va">SFO_SFO.ff</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"m1"</span>, sink <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"><span class="va">fit.ff</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO.ff</span>, <span class="va">FOCUS_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">fit.ff.s</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/saemix/man/summary-methods.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">fit.ff</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">fit.ff.s</span><span class="op">$</span><span class="va">par</span>, <span class="fl">3</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Std. Error Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 99.5985 1.5702 96.404 102.79</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent -2.3157 0.0409 -2.399 -2.23</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_m1 -5.2475 0.1332 -5.518 -4.98</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_qlogis 0.0579 0.0893 -0.124 0.24</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 3.1255 0.3585 2.396 3.85</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">fit.ff.s</span><span class="op">$</span><span class="va">bpar</span>, <span class="fl">3</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Estimate se_notrans t value Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 99.59848 1.57022 63.43 2.30e-36 96.40383 102.7931</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.09870 0.00403 24.47 4.96e-23 0.09082 0.1073</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1 0.00526 0.00070 7.51 6.16e-09 0.00401 0.0069</span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_m1 0.51448 0.02230 23.07 3.10e-22 0.46912 0.5596</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 3.12550 0.35852 8.72 2.24e-10 2.39609 3.8549</span> +<span class="r-in"><span class="va">initials</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"f_parent_to_m1"</span> <span class="op">=</span> <span class="fl">0.5</span><span class="op">)</span></span> +<span class="r-in"><span class="va">transformed</span> <span class="op"><-</span> <span class="fu">transform_odeparms</span><span class="op">(</span><span class="va">initials</span>, <span class="va">SFO_SFO.ff</span><span class="op">)</span></span> +<span class="r-in"><span class="fu">backtransform_odeparms</span><span class="op">(</span><span class="va">transformed</span>, <span class="va">SFO_SFO.ff</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> f_parent_to_m1 </span> +<span class="r-out co"><span class="r-pr">#></span> 0.5 </span> +<span class="r-in"></span> +<span class="r-in"><span class="co"># And without sink</span></span> +<span class="r-in"><span class="va">SFO_SFO.ff.2</span> <span class="op"><-</span> <span class="fu"><a href="mkinmod.html">mkinmod</a></span><span class="op">(</span></span> +<span class="r-in"> parent <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span>, to <span class="op">=</span> <span class="st">"m1"</span>, sink <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span>,</span> +<span class="r-in"> m1 <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>type <span class="op">=</span> <span class="st">"SFO"</span><span class="op">)</span>,</span> +<span class="r-in"> use_of_ff <span class="op">=</span> <span class="st">"max"</span><span class="op">)</span></span> +<span class="r-msg co"><span class="r-pr">#></span> Temporary DLL for differentials generated and loaded</span> +<span class="r-in"></span> +<span class="r-in"></span> +<span class="r-in"><span class="va">fit.ff.2</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="va">SFO_SFO.ff.2</span>, <span class="va">FOCUS_D</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="va">fit.ff.2.s</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/pkg/saemix/man/summary-methods.html" class="external-link">summary</a></span><span class="op">(</span><span class="va">fit.ff.2</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">fit.ff.2.s</span><span class="op">$</span><span class="va">par</span>, <span class="fl">3</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Estimate Std. Error Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 84.79 3.012 78.67 90.91</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_parent -2.76 0.082 -2.92 -2.59</span> +<span class="r-out co"><span class="r-pr">#></span> log_k_m1 -4.21 0.123 -4.46 -3.96</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 8.22 0.943 6.31 10.14</span> +<span class="r-in"><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">fit.ff.2.s</span><span class="op">$</span><span class="va">bpar</span>, <span class="fl">3</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> Estimate se_notrans t value Pr(>t) Lower Upper</span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 84.7916 3.01203 28.15 1.92e-25 78.6704 90.913</span> +<span class="r-out co"><span class="r-pr">#></span> k_parent 0.0635 0.00521 12.19 2.91e-14 0.0538 0.075</span> +<span class="r-out co"><span class="r-pr">#></span> k_m1 0.0148 0.00182 8.13 8.81e-10 0.0115 0.019</span> +<span class="r-out co"><span class="r-pr">#></span> sigma 8.2229 0.94323 8.72 1.73e-10 6.3060 10.140</span> +<span class="r-in"><span class="co"># }</span></span> +<span class="r-in"></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> diff --git a/docs/reference/update.mkinfit-1.png b/docs/reference/update.mkinfit-1.png Binary files differindex df8473c1..12fe1f5b 100644 --- a/docs/reference/update.mkinfit-1.png +++ b/docs/reference/update.mkinfit-1.png diff --git a/docs/reference/update.mkinfit-2.png b/docs/reference/update.mkinfit-2.png Binary files differindex 13c99b44..21817f94 100644 --- a/docs/reference/update.mkinfit-2.png +++ b/docs/reference/update.mkinfit-2.png diff --git a/docs/reference/update.mkinfit.html b/docs/reference/update.mkinfit.html index 09050e53..036283d5 100644 --- a/docs/reference/update.mkinfit.html +++ b/docs/reference/update.mkinfit.html @@ -1,70 +1,15 @@ -<!-- Generated by pkgdown: do not edit by hand --> <!DOCTYPE html> -<html lang="en"> - <head> - <meta charset="utf-8"> -<meta http-equiv="X-UA-Compatible" content="IE=edge"> -<meta name="viewport" content="width=device-width, initial-scale=1.0"> - -<title>Update an mkinfit model with different arguments — update.mkinfit • mkin</title> - - -<!-- jquery --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script> -<!-- Bootstrap --> - -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous" /> - -<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script> - -<!-- bootstrap-toc --> -<link rel="stylesheet" href="../bootstrap-toc.css"> -<script src="../bootstrap-toc.js"></script> - -<!-- Font Awesome icons --> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous" /> -<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous" /> - -<!-- clipboard.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script> - -<!-- headroom.js --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script> - -<!-- pkgdown --> -<link href="../pkgdown.css" rel="stylesheet"> -<script src="../pkgdown.js"></script> - - - - -<meta property="og:title" content="Update an mkinfit model with different arguments — update.mkinfit" /> -<meta property="og:description" content="This function will return an updated mkinfit object. The fitted degradation +<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Update an mkinfit model with different arguments — update.mkinfit • mkin</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Update an mkinfit model with different arguments — update.mkinfit"><meta property="og:description" content="This function will return an updated mkinfit object. The fitted degradation model parameters from the old fit are used as starting values for the updated fit. Values specified as 'parms.ini' and/or 'state.ini' will -override these starting values." /> - - - - -<!-- mathjax --> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script> -<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script> - -<!--[if lt IE 9]> +override these starting values."><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]> <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script> <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script> -<![endif]--> - - +<![endif]--></head><body data-spy="scroll" data-target="#toc"> + - </head> - - <body data-spy="scroll" data-target="#toc"> <div class="container template-reference-topic"> - <header> - <div class="navbar navbar-default navbar-fixed-top" role="navigation"> + <header><div class="navbar navbar-default navbar-fixed-top" role="navigation"> <div class="container"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> @@ -75,13 +20,12 @@ override these starting values." /> </button> <span class="navbar-brand"> <a class="navbar-link" href="../index.html">mkin</a> - <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.0.3</span> + <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.1.0</span> </span> </div> <div id="navbar" class="navbar-collapse collapse"> - <ul class="nav navbar-nav"> - <li> + <ul class="nav navbar-nav"><li> <a href="../reference/index.html">Functions and data</a> </li> <li class="dropdown"> @@ -90,8 +34,7 @@ override these starting values." /> <span class="caret"></span> </a> - <ul class="dropdown-menu" role="menu"> - <li> + <ul class="dropdown-menu" role="menu"><li> <a href="../articles/mkin.html">Introduction to mkin</a> </li> <li> @@ -101,6 +44,9 @@ override these starting values." /> <a href="../articles/FOCUS_L.html">Example evaluation of FOCUS Laboratory Data L1 to L3</a> </li> <li> + <a href="../articles/web_only/dimethenamid_2018.html">Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models</a> + </li> + <li> <a href="../articles/web_only/FOCUS_Z.html">Example evaluation of FOCUS Example Dataset Z</a> </li> <li> @@ -115,34 +61,27 @@ override these starting values." /> <li> <a href="../articles/web_only/benchmarks.html">Some benchmark timings</a> </li> - </ul> -</li> + </ul></li> <li> <a href="../news/index.html">News</a> </li> - </ul> - <ul class="nav navbar-nav navbar-right"> - <li> - <a href="https://github.com/jranke/mkin/"> + </ul><ul class="nav navbar-nav navbar-right"><li> + <a href="https://github.com/jranke/mkin/" class="external-link"> <span class="fab fa-github fa-lg"></span> </a> </li> - </ul> - - </div><!--/.nav-collapse --> + </ul></div><!--/.nav-collapse --> </div><!--/.container --> </div><!--/.navbar --> - </header> - -<div class="row"> + </header><div class="row"> <div class="col-md-9 contents"> <div class="page-header"> <h1>Update an mkinfit model with different arguments</h1> - <small class="dont-index">Source: <a href='https://github.com/jranke/mkin/blob/master/R/update.mkinfit.R'><code>R/update.mkinfit.R</code></a></small> + <small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/update.mkinfit.R" class="external-link"><code>R/update.mkinfit.R</code></a></small> <div class="hidden name"><code>update.mkinfit.Rd</code></div> </div> @@ -153,66 +92,62 @@ updated fit. Values specified as 'parms.ini' and/or 'state.ini' will override these starting values.</p> </div> - <pre class="usage"><span class='co'># S3 method for mkinfit</span> -<span class='fu'><a href='https://rdrr.io/r/stats/update.html'>update</a></span><span class='op'>(</span><span class='va'>object</span>, <span class='va'>...</span>, evaluate <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span></pre> - - <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2> - <table class="ref-arguments"> - <colgroup><col class="name" /><col class="desc" /></colgroup> - <tr> - <th>object</th> - <td><p>An mkinfit object to be updated</p></td> - </tr> - <tr> - <th>...</th> - <td><p>Arguments to <code><a href='mkinfit.html'>mkinfit</a></code> that should replace + <div id="ref-usage"> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="co"># S3 method for mkinfit</span> +<span class="fu"><a href="https://rdrr.io/r/stats/update.html" class="external-link">update</a></span><span class="op">(</span><span class="va">object</span>, <span class="va">...</span>, evaluate <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></code></pre></div> + </div> + + <div id="arguments"> + <h2>Arguments</h2> + <dl><dt>object</dt> +<dd><p>An mkinfit object to be updated</p></dd> +<dt>...</dt> +<dd><p>Arguments to <code><a href="mkinfit.html">mkinfit</a></code> that should replace the arguments from the original call. Arguments set to NULL will -remove arguments given in the original call</p></td> - </tr> - <tr> - <th>evaluate</th> - <td><p>Should the call be evaluated or returned as a call</p></td> - </tr> - </table> - - - <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2> - <pre class="examples"><div class='input'><span class='co'># \dontrun{</span> -<span class='va'>fit</span> <span class='op'><-</span> <span class='fu'><a href='mkinfit.html'>mkinfit</a></span><span class='op'>(</span><span class='st'>"SFO"</span>, <span class='fu'><a href='https://rdrr.io/r/base/subset.html'>subset</a></span><span class='op'>(</span><span class='va'>FOCUS_2006_D</span>, <span class='va'>value</span> <span class='op'>!=</span> <span class='fl'>0</span><span class='op'>)</span>, quiet <span class='op'>=</span> <span class='cn'>TRUE</span><span class='op'>)</span> -<span class='fu'><a href='parms.html'>parms</a></span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span> -</div><div class='output co'>#> parent_0 k_parent sigma -#> 99.44423885 0.09793574 3.39632469 </div><div class='input'><span class='fu'><a href='plot.mkinfit.html'>plot_err</a></span><span class='op'>(</span><span class='va'>fit</span><span class='op'>)</span> -</div><div class='img'><img src='update.mkinfit-1.png' alt='' width='700' height='433' /></div><div class='input'><span class='va'>fit_2</span> <span class='op'><-</span> <span class='fu'><a href='https://rdrr.io/r/stats/update.html'>update</a></span><span class='op'>(</span><span class='va'>fit</span>, error_model <span class='op'>=</span> <span class='st'>"tc"</span><span class='op'>)</span> -<span class='fu'><a href='parms.html'>parms</a></span><span class='op'>(</span><span class='va'>fit_2</span><span class='op'>)</span> -</div><div class='output co'>#> parent_0 k_parent sigma_low rsd_high -#> 1.008549e+02 1.005665e-01 3.752222e-03 6.763434e-02 </div><div class='input'><span class='fu'><a href='plot.mkinfit.html'>plot_err</a></span><span class='op'>(</span><span class='va'>fit_2</span><span class='op'>)</span> -</div><div class='img'><img src='update.mkinfit-2.png' alt='' width='700' height='433' /></div><div class='input'><span class='co'># }</span> -</div></pre> +remove arguments given in the original call</p></dd> +<dt>evaluate</dt> +<dd><p>Should the call be evaluated or returned as a call</p></dd> +</dl></div> + + <div id="ref-examples"> + <h2>Examples</h2> + <div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span class="co"># \dontrun{</span></span> +<span class="r-in"><span class="va">fit</span> <span class="op"><-</span> <span class="fu"><a href="mkinfit.html">mkinfit</a></span><span class="op">(</span><span class="st">"SFO"</span>, <span class="fu"><a href="https://rdrr.io/pkg/saemix/man/subset.html" class="external-link">subset</a></span><span class="op">(</span><span class="va">FOCUS_2006_D</span>, <span class="va">value</span> <span class="op">!=</span> <span class="fl">0</span><span class="op">)</span>, quiet <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="parms.html">parms</a></span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 k_parent sigma </span> +<span class="r-out co"><span class="r-pr">#></span> 99.44423885 0.09793574 3.39632469 </span> +<span class="r-in"><span class="fu"><a href="plot.mkinfit.html">plot_err</a></span><span class="op">(</span><span class="va">fit</span><span class="op">)</span></span> +<span class="r-plt img"><img src="update.mkinfit-1.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="va">fit_2</span> <span class="op"><-</span> <span class="fu"><a href="https://rdrr.io/r/stats/update.html" class="external-link">update</a></span><span class="op">(</span><span class="va">fit</span>, error_model <span class="op">=</span> <span class="st">"tc"</span><span class="op">)</span></span> +<span class="r-in"><span class="fu"><a href="parms.html">parms</a></span><span class="op">(</span><span class="va">fit_2</span><span class="op">)</span></span> +<span class="r-out co"><span class="r-pr">#></span> parent_0 k_parent sigma_low rsd_high </span> +<span class="r-out co"><span class="r-pr">#></span> 1.008549e+02 1.005665e-01 3.752222e-03 6.763434e-02 </span> +<span class="r-in"><span class="fu"><a href="plot.mkinfit.html">plot_err</a></span><span class="op">(</span><span class="va">fit_2</span><span class="op">)</span></span> +<span class="r-plt img"><img src="update.mkinfit-2.png" alt="" width="700" height="433"></span> +<span class="r-in"><span class="co"># }</span></span> +</code></pre></div> + </div> </div> <div class="col-md-3 hidden-xs hidden-sm" id="pkgdown-sidebar"> - <nav id="toc" data-toggle="toc" class="sticky-top"> - <h2 data-toc-skip>Contents</h2> - </nav> - </div> + <nav id="toc" data-toggle="toc" class="sticky-top"><h2 data-toc-skip>Contents</h2> + </nav></div> </div> - <footer> - <div class="copyright"> - <p>Developed by Johannes Ranke.</p> + <footer><div class="copyright"> + <p></p><p>Developed by Johannes Ranke.</p> </div> <div class="pkgdown"> - <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.6.1.</p> + <p></p><p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p> </div> - </footer> - </div> + </footer></div> - </body> -</html> + + </body></html> |
