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-rw-r--r--man/mkinfit.Rd18
1 files changed, 14 insertions, 4 deletions
diff --git a/man/mkinfit.Rd b/man/mkinfit.Rd
index bd7f73b7..c99e146c 100644
--- a/man/mkinfit.Rd
+++ b/man/mkinfit.Rd
@@ -21,7 +21,8 @@ mkinfit(mkinmod, observed,
fixed_parms = NULL, fixed_initials = names(mkinmod$diffs)[-1],
solution_type = "auto",
method.ode = "lsoda",
- method.modFit = "Marq",
+ method.modFit = c("Marq", "Port", "SANN", "Nelder-Mead", "BFSG", "CG", "L-BFGS-B"),
+ maxit.modFit = "auto",
control.modFit = list(),
transform_rates = TRUE,
transform_fractions = TRUE,
@@ -102,12 +103,21 @@ mkinfit(mkinmod, observed,
recommended as it is less prone to get trapped in local minima and depends
less on starting values for parameters. However, it needs more iterations.
- When using "Pseudo", "upper" and "lower" need to be specified for the
- transformed parameters.
+ The "Pseudo" algorithm is not included because it needs finite parameter bounds
+ which are currently not supported.
+
+ The "Newton" algorithm is not included because its number of iterations
+ can not be controlled by \code{control.modFit} and it does not appear
+ to provide advantages over the other algorithms.
+ }
+ \item{maxit.modFit}{
+ Maximum number of iterations in the optimisation. If not "auto", this will
+ be passed to the method called by \code{\link{modFit}}, overriding
+ what may be specified in the next argument \code{control.modFit}.
}
\item{control.modFit}{
Additional arguments passed to the optimisation method used by
- \code{\link{modFit}}.
+ \code{\link{modFit}}.
}
\item{transform_rates}{
Boolean specifying if kinetic rate constants should be transformed in the

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