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-rw-r--r--man/confint.mkinfit.Rd17
1 files changed, 13 insertions, 4 deletions
diff --git a/man/confint.mkinfit.Rd b/man/confint.mkinfit.Rd
index 943904b9..29959e52 100644
--- a/man/confint.mkinfit.Rd
+++ b/man/confint.mkinfit.Rd
@@ -5,9 +5,9 @@
\title{Confidence intervals for parameters of mkinfit objects}
\usage{
\method{confint}{mkinfit}(object, parm, level = 0.95, alpha = 1 -
- level, method = c("profile", "quadratic"), transformed = TRUE,
- backtransform = TRUE, distribution = c("student_t", "normal"),
- quiet = FALSE, ...)
+ level, cutoff, method = c("profile", "quadratic"),
+ transformed = TRUE, backtransform = TRUE,
+ distribution = c("student_t", "normal"), quiet = FALSE, ...)
}
\arguments{
\item{object}{An \code{\link{mkinfit}} object}
@@ -19,6 +19,10 @@ confidence intervals. If missing, all parameters are considered.}
\item{alpha}{The allowed error probability, overrides 'level' if specified.}
+\item{cutoff}{Possibility to specify an alternative cutoff for the difference
+in the log-likelihoods at the confidence boundary. Specifying an explicit
+cutoff value overrides arguments 'level' and 'alpha'}
+
\item{method}{The 'profile' method searches the parameter space for the
cutoff of the confidence intervals by means of a likelihood ratio test.
The 'quadratic' method approximates the likelihood function at the
@@ -45,7 +49,9 @@ A matrix with columns giving lower and upper confidence limits for
each parameter.
}
\description{
-Confidence intervals for parameters of mkinfit objects
+The default method 'profile' is based on the profile likelihood for each
+parameter. The method uses two nested optimisations. The speed of the method
+could likely be improved by using the method of Venzon and Moolgavkar (1988).
}
\examples{
f <- mkinfit("SFO", FOCUS_2006_C, quiet = TRUE)
@@ -57,4 +63,7 @@ confint(f, method = "quadratic")
\references{
Pawitan Y (2013) In all likelihood - Statistical modelling and
inference using likelihood. Clarendon Press, Oxford.
+ Venzon DJ and Moolgavkar SH (1988) A Method for Computing
+ Profile-Likelihood Based Confidence Intervals, Applied Statistics, 37,
+ 87–94.
}

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