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2020-11-09Remove outdated doc pageJohannes Ranke1-1202/+0
2020-11-09Doc improvementsJohannes Ranke4-6/+9
2020-11-09Some work on example code, pkgdown updateJohannes Ranke14-212/+451
2020-11-09Custom analytical solutions for saemixJohannes Ranke6-70/+183
Currently SFO-SFO and DFOP-SFO. Speed increase factor about 60
2020-11-08The call to saemix.predict fails with DFOP-SFOJohannes Ranke4-6/+6
2020-11-08Update static docsJohannes Ranke7-24/+482
2020-11-08Improve saem method, add summaryJohannes Ranke13-82/+459
Also make the endpoints function work for saem objects.
2020-11-07Update static docs for dev versionJohannes Ranke9-121/+450
2020-11-07Create saem generic for fitting saemix modelsJohannes Ranke10-123/+103
The reasons for this decision were - Creating an saemix generic in the saemix package caused problems with roxygen, because functions like saemix.plot.xy were documented in their help files as S3 methods, although explicitly exported with @export - Creating an saemix generic in this package is possible, but would make it necessary to load samix with exclude = "saemix" in order to avoid overwriting the generic when loading saemix. - The return object of such an saemix generic in this package cannot be an S3 class with class attribute c("saemix.mmkin", "SaemixObject") similar to nlme.mmkin, as saemix returns an S4 class. - Extending the S4 class SaemixObject using simple inheritance to a class SaemixMmkinObject with additional slots did not work as expected. When the initialize method was left untouched, it prevented creation of an SaemixMmkinObject even if it was based on an initialised SaemixObject, as the initialize method seems to always be called by new(). This could potentially be circumvented by a coerce method. If an alternative initialize method was used, an SaemixMmkinObject could be created. However, the methods written for SaemixObjects only worked in some instances, either because they checked for the class, and not for class inheritance (like compare.saemix), or because the initialize method was called for some reason. Therefore, the idea of creating a derived S4 class was abandoned. - A side effect of this decision is that the introduction of the saem generic opens the possibility to use the same generic also for other backends like nlmixr with the SAEM algorithm.
2020-11-07Make deSolve predictions within saemix robustJohannes Ranke4-39/+63
Also, exclude the saemix function when loading saemix in the example code, to prevent overriding our generic
2020-11-06Make saemix an S3 generic in this packageJohannes Ranke3-59/+113
This commit also defined saemix.mmkin for mmkin row objects. This works fine, but if we set the class of the returned object to c("saemix.mmkin", "saemix"), it is not an S4 class any more which make it impossible to use saemix functions on it.
2020-11-06Update benchmarks for dev versionJohannes Ranke5-69/+129
2020-11-06Fast analytical solutions for saemix, update.mmkinJohannes Ranke56-741/+1454
Also, use logit transformation for g and for solitary formation fractions, addressing #10.
2020-11-05Fix mean_degparms() if only one optimised parameterJohannes Ranke1-5/+7
2020-11-05Fix link and update docsJohannes Ranke10-97/+121
2020-11-04Revert to use starting values for random effects in nlme.mmkinJohannes Ranke7-20/+10
2020-11-04Update dynamic docsJohannes Ranke2-9/+13
2020-11-04Deprecate cores > 1 in saemix_modelJohannes Ranke1-3/+5
2020-11-03Do not test residuals per default, improve nlme.mmkinJohannes Ranke3-7/+14
Do not give starting values for random effects in nlme.mmkin.
2020-10-27Add summary method for nlme.mmkin objectsJohannes Ranke22-93/+949
Improve and update docs
2020-10-26Small editorial changeJohannes Ranke1-1/+1
2020-10-26Put the legend in its own area for plot.nlme.mmkinJohannes Ranke21-115/+121
2020-10-26Fix another bug in plot.nlme.mmkinJohannes Ranke1-1/+2
2020-10-26Fix a bug in plot.nlme.mmkinJohannes Ranke1-1/+3
2020-10-24Fix a bug for nlme with parent only, improve examplesJohannes Ranke13-150/+32
2020-10-24Improve plot layoutJohannes Ranke6-61/+23
2020-10-24Plot method for nlme.mmkin objectsJohannes Ranke20-189/+624
Update docs
2020-10-24Printing method for mmkin objectsJohannes Ranke3-8/+53
2020-10-22Really fix check for nlme::varConstPropJohannes Ranke4-6/+53
And add output for nlme fit translating the mkinfit error model "obs" into nlme::varIdent().
2020-10-22Fix check for nlme::varConstPropJohannes Ranke2-1/+1
2020-10-22Try 2 to make travis use nlme from my drat repoJohannes Ranke1-1/+3
2020-10-22Update pkgdown docsJohannes Ranke22-113/+201
2020-10-22Improve interface to experimental version of nlmeJohannes Ranke9-24/+158
The experimental nlme version in my drat repository contains the variance function structure varConstProp which makes it possible to use the two-component error model in generalized nonlinear models using nlme::gnls() and in mixed effects models using nlme::nlme().
2020-10-15More gentle example for saemix with combined error modelJohannes Ranke11-49/+47
2020-10-15Get current nlme version from CRAN on TravisJohannes Ranke3-3/+6
Also commit the dontrun instruction for saemix I had wanted to commit and switch back to devel mode for pkgdown
2020-10-15Don't run saemix examples on travis for nowJohannes Ranke1-1/+2
2020-10-15Update online docs for release versionJohannes Ranke142-2297/+2727
2020-10-15Updating docs of current dev versionJohannes Ranke36-156/+522
2020-10-15Use my saemix repo for travisJohannes Ranke1-1/+1
The official repo is not installable at the moment
2020-10-15Reintroduce saemix helper functionsJohannes Ranke10-47/+273
2020-10-08saemix dev version is not installable at the momentJohannes Ranke1-2/+0
2020-10-08Fix another URL, add devcheck targetv0.9.50.3Johannes Ranke11-11/+85
2020-10-08Fix issues for releaseJohannes Ranke92-1670/+1285
2020-10-08Avoid dep on dev version of saemix for releaseJohannes Ranke3-139/+3
2020-09-10Regenerate docs with current roxygenJohannes Ranke3-4/+6
2020-09-01Merge branch 'master' of kolab.jrwb.de:mkinJohannes Ranke3-31/+1
2020-09-01Back-calculated DT50 values for biphasic modelsJohannes Ranke2-1/+12
2020-07-20Require upcoming nlme version, remove anova.nlme.mmkinJohannes Ranke3-31/+1
The method is no longer necessary, now that Bug 17761 is fixed upstream https://bugs.r-project.org/bugzilla/show_bug.cgi?id=17761
2020-07-17mkinfit: Ignore unused components of state.iniJohannes Ranke5-6/+20
2020-07-15Bump date to trigger Travis build after clearing cacheJohannes Ranke1-1/+1

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