From 804a5cb47fcdc823d41c585729ace151b283ca65 Mon Sep 17 00:00:00 2001 From: Johannes Ranke Date: Fri, 4 Aug 2023 13:27:41 +0200 Subject: Mesotrione data and vignette The vignette illustrates pH dependent degradation (covariate modelling) with some detail for the parent compound. Also, a bug in the saem method of the illparms function was fixed, which prevented to find ill-defined parameters in cases where e.g. slopes of covariate models have a negative estimate. --- R/illparms.R | 4 ++-- 1 file changed, 2 insertions(+), 2 deletions(-) (limited to 'R') diff --git a/R/illparms.R b/R/illparms.R index eef4bd33..68a6bff6 100644 --- a/R/illparms.R +++ b/R/illparms.R @@ -106,7 +106,7 @@ illparms.saem.mmkin <- function(object, conf.level = 0.95, random = TRUE, errmod ill_parms <- c(ill_parms, names(which(ill_parms_random))) } if (errmod) { - ill_parms_errmod <- ints$errmod[, "lower"] < 0 & ints$errmod[, "est."] > 0 + ill_parms_errmod <- ints$errmod[, "lower"] < 0 & ints$errmod[, "upper"] > 0 ill_parms <- c(ill_parms, names(which(ill_parms_errmod))) } if (slopes) { @@ -115,7 +115,7 @@ illparms.saem.mmkin <- function(object, conf.level = 0.95, random = TRUE, errmod ci <- object$so@results@conf.int rownames(ci) <- ci$name slope_ci <- ci[slope_names, ] - ill_parms_slopes <- slope_ci[, "lower"] < 0 & slope_ci[, "estimate"] > 0 + ill_parms_slopes <- slope_ci[, "lower"] < 0 & slope_ci[, "upper"] > 0 ill_parms <- c(ill_parms, slope_names[ill_parms_slopes]) } } -- cgit v1.2.1