From 6178249bbb5e9de7cb7f34287ee7de28a68fed6c Mon Sep 17 00:00:00 2001 From: Johannes Ranke Date: Wed, 10 Aug 2022 15:38:17 +0200 Subject: Change dev branch used for docs, update static docs --- docs/dev/reference/summary.saem.mmkin.html | 454 +++++++++++++++++++++++++---- 1 file changed, 401 insertions(+), 53 deletions(-) (limited to 'docs/dev/reference/summary.saem.mmkin.html') diff --git a/docs/dev/reference/summary.saem.mmkin.html b/docs/dev/reference/summary.saem.mmkin.html index febf25b4..6cab9c5f 100644 --- a/docs/dev/reference/summary.saem.mmkin.html +++ b/docs/dev/reference/summary.saem.mmkin.html @@ -21,7 +21,7 @@ endpoints such as formation fractions and DT50 values. Optionally mkin - 1.1.0 + 1.1.2 @@ -30,7 +30,7 @@ endpoints such as formation fractions and DT50 values. Optionally Functions and data
  • -
  • Example evaluation of FOCUS Laboratory Data L1 to L3
    • +
  • + Example evaluations of dimethenamid data from 2018 with nonlinear mixed-effects models +
  • Example evaluation of FOCUS Example Dataset Z
    • @@ -92,59 +95,88 @@ endpoints such as formation fractions and DT50 values. Optionally
    - 
    # S3 method for saem.mmkin
-summary(object, data = FALSE, verbose = FALSE, distimes = TRUE, ...)
-
-# S3 method for summary.saem.mmkin
-print(x, digits = max(3, getOption("digits") - 3), verbose = x$verbose, ...)
    + 
    # S3 method for saem.mmkin
+summary(object, data = FALSE, verbose = FALSE, distimes = TRUE, ...)
+
+# S3 method for summary.saem.mmkin
+print(x, digits = max(3, getOption("digits") - 3), verbose = x$verbose, ...)

    Arguments

    object

    an object of class saem.mmkin

    + +
    data

    logical, indicating whether the full data should be included in the summary.

    + +
    verbose

    Should the summary be verbose?

    + +
    distimes

    logical, indicating whether DT50 and DT90 values should be included.

    + +
    ...

    optional arguments passed to methods like print.

    + +
    x

    an object of class summary.saem.mmkin

    + +
    digits

    Number of digits to use for printing

    +

    Value

    -

    The summary function returns a list based on the saemix::SaemixObjectobtained in the fit, with at least the following additional components

    + + +

    The summary function returns a list based on the saemix::SaemixObject

    + + +

    obtained in the fit, with at least the following additional components

    saemixversion, mkinversion, Rversion

    The saemix, mkin and R versions used

    +
    date.fit, date.summary

    The dates where the fit and the summary were produced

    +
    diffs

    The differential equations used in the degradation model

    +
    use_of_ff

    Was maximum or minimum use made of formation fractions

    +
    data

    The data

    +
    confint_trans

    Transformed parameters as used in the optimisation, with confidence intervals

    +
    confint_back

    Backtransformed parameters, with confidence intervals if available

    +
    confint_errmod

    Error model parameters with confidence intervals

    +
    ff

    The estimated formation fractions derived from the fitted model.

    +
    distimes

    The DT50 and DT90 values for each observed variable.

    +
    SFORB

    If applicable, eigenvalues of SFORB components of the model.

    +

    The print method is called for its side effect, i.e. printing the summary.

    @@ -155,50 +187,366 @@ saemix authors for the parts inherited from saemix.

    Examples

    - 
    # Generate five datasets following DFOP-SFO kinetics
-sampling_times = c(0, 1, 3, 7, 14, 28, 60, 90, 120)
-dfop_sfo <- mkinmod(parent = mkinsub("DFOP", "m1"),
- m1 = mkinsub("SFO"), quiet = TRUE)
-set.seed(1234)
-k1_in <- rlnorm(5, log(0.1), 0.3)
-k2_in <- rlnorm(5, log(0.02), 0.3)
-g_in <- plogis(rnorm(5, qlogis(0.5), 0.3))
-f_parent_to_m1_in <- plogis(rnorm(5, qlogis(0.3), 0.3))
-k_m1_in <- rlnorm(5, log(0.02), 0.3)
-
-pred_dfop_sfo <- function(k1, k2, g, f_parent_to_m1, k_m1) {
-  mkinpredict(dfop_sfo,
-    c(k1 = k1, k2 = k2, g = g, f_parent_to_m1 = f_parent_to_m1, k_m1 = k_m1),
-    c(parent = 100, m1 = 0),
-    sampling_times)
-}
-
-ds_mean_dfop_sfo <- lapply(1:5, function(i) {
-  mkinpredict(dfop_sfo,
-    c(k1 = k1_in[i], k2 = k2_in[i], g = g_in[i],
-      f_parent_to_m1 = f_parent_to_m1_in[i], k_m1 = k_m1_in[i]),
-    c(parent = 100, m1 = 0),
-    sampling_times)
-})
-names(ds_mean_dfop_sfo) <- paste("ds", 1:5)
-
-ds_syn_dfop_sfo <- lapply(ds_mean_dfop_sfo, function(ds) {
-  add_err(ds,
-    sdfunc = function(value) sqrt(1^2 + value^2 * 0.07^2),
-    n = 1)[[1]]
-})
-
-# \dontrun{
-# Evaluate using mmkin and saem
-f_mmkin_dfop_sfo <- mmkin(list(dfop_sfo), ds_syn_dfop_sfo,
-  quiet = TRUE, error_model = "tc", cores = 5)
-f_saem_dfop_sfo <- saem(f_mmkin_dfop_sfo)
-#>  
-#> Error in rxModelVars_(obj): Not compatible with STRSXP: [type=NULL].
-summary(f_saem_dfop_sfo, data = TRUE)
-#> Error in h(simpleError(msg, call)): error in evaluating the argument 'object' in selecting a method for function 'summary': object 'f_saem_dfop_sfo' not found
-# }
-
+    
    # Generate five datasets following DFOP-SFO kinetics
+sampling_times = c(0, 1, 3, 7, 14, 28, 60, 90, 120)
+dfop_sfo <- mkinmod(parent = mkinsub("DFOP", "m1"),
+ m1 = mkinsub("SFO"), quiet = TRUE)
+set.seed(1234)
+k1_in <- rlnorm(5, log(0.1), 0.3)
+k2_in <- rlnorm(5, log(0.02), 0.3)
+g_in <- plogis(rnorm(5, qlogis(0.5), 0.3))
+f_parent_to_m1_in <- plogis(rnorm(5, qlogis(0.3), 0.3))
+k_m1_in <- rlnorm(5, log(0.02), 0.3)
+
+pred_dfop_sfo <- function(k1, k2, g, f_parent_to_m1, k_m1) {
+  mkinpredict(dfop_sfo,
+    c(k1 = k1, k2 = k2, g = g, f_parent_to_m1 = f_parent_to_m1, k_m1 = k_m1),
+    c(parent = 100, m1 = 0),
+    sampling_times)
+}
+
+ds_mean_dfop_sfo <- lapply(1:5, function(i) {
+  mkinpredict(dfop_sfo,
+    c(k1 = k1_in[i], k2 = k2_in[i], g = g_in[i],
+      f_parent_to_m1 = f_parent_to_m1_in[i], k_m1 = k_m1_in[i]),
+    c(parent = 100, m1 = 0),
+    sampling_times)
+})
+names(ds_mean_dfop_sfo) <- paste("ds", 1:5)
+
+ds_syn_dfop_sfo <- lapply(ds_mean_dfop_sfo, function(ds) {
+  add_err(ds,
+    sdfunc = function(value) sqrt(1^2 + value^2 * 0.07^2),
+    n = 1)[[1]]
+})
+
+# \dontrun{
+# Evaluate using mmkin and saem
+f_mmkin_dfop_sfo <- mmkin(list(dfop_sfo), ds_syn_dfop_sfo,
+  quiet = TRUE, error_model = "tc", cores = 5)
+f_saem_dfop_sfo <- saem(f_mmkin_dfop_sfo)
+print(f_saem_dfop_sfo)
+#> Kinetic nonlinear mixed-effects model fit by SAEM
+#> Structural model:
+#> d_parent/dt = - ((k1 * g * exp(-k1 * time) + k2 * (1 - g) * exp(-k2 *
+#>            time)) / (g * exp(-k1 * time) + (1 - g) * exp(-k2 * time)))
+#>            * parent
+#> d_m1/dt = + f_parent_to_m1 * ((k1 * g * exp(-k1 * time) + k2 * (1 - g)
+#>            * exp(-k2 * time)) / (g * exp(-k1 * time) + (1 - g) *
+#>            exp(-k2 * time))) * parent - k_m1 * m1
+#> 
+#> Data:
+#> 171 observations of 2 variable(s) grouped in 5 datasets
+#> 
+#> Likelihood computed by importance sampling
+#>     AIC   BIC logLik
+#>   828.1 822.7 -400.1
+#> 
+#> Fitted parameters:
+#>                     estimate    lower     upper
+#> parent_0           100.74378 97.81291 103.67465
+#> log_k_m1            -4.06168 -4.17104  -3.95231
+#> f_parent_qlogis     -0.92584 -1.31273  -0.53894
+#> log_k1              -2.81914 -3.60206  -2.03623
+#> log_k2              -3.63916 -4.32672  -2.95161
+#> g_qlogis            -0.02927 -1.15247   1.09394
+#> a.1                  0.86164  0.67928   1.04400
+#> b.1                  0.07973  0.06437   0.09509
+#> SD.parent_0          0.73313 -7.46512   8.93137
+#> SD.log_k_m1          0.06488 -0.06041   0.19017
+#> SD.f_parent_qlogis   0.41955  0.15206   0.68705
+#> SD.log_k1            0.81750  0.29140   1.34361
+#> SD.log_k2            0.75265  0.27939   1.22590
+#> SD.g_qlogis          0.34411 -1.70964   2.39786
+illparms(f_saem_dfop_sfo)
+#> [1] "sd(parent_0)" "sd(log_k_m1)" "sd(g_qlogis)"
+f_saem_dfop_sfo_2 <- update(f_saem_dfop_sfo, covariance.model = diag(c(0, 0, 1, 1, 1, 0)))
+illparms(f_saem_dfop_sfo_2)
+#> character(0)
+intervals(f_saem_dfop_sfo_2)
+#> Approximate 95% confidence intervals
+#> 
+#>  Fixed effects:
+#>                      lower         est.        upper
+#> parent_0       97.54844979 100.46239264 103.37633550
+#> k_m1            0.01575805   0.01729111   0.01897331
+#> f_parent_to_m1  0.21014925   0.28626877   0.37680664
+#> k1              0.02651112   0.05601399   0.11834908
+#> k2              0.01326524   0.02649799   0.05293107
+#> g               0.31467778   0.51297098   0.70726363
+#> 
+#>  Random effects:
+#>                         lower      est.     upper
+#> sd(f_parent_qlogis) 0.1658367 0.4471180 0.7283993
+#> sd(log_k1)          0.2768757 0.7929203 1.3089649
+#> sd(log_k2)          0.2693629 0.7566116 1.2438602
+#> 
+#>  
+#>          lower       est.      upper
+#> a.1 0.70273100 0.88750764 1.07228428
+#> b.1 0.06781347 0.08328016 0.09874685
+summary(f_saem_dfop_sfo_2, data = TRUE)
+#> saemix version used for fitting:      3.1 
+#> mkin version used for pre-fitting:  1.1.2 
+#> R version used for fitting:         4.2.1 
+#> Date of fit:     Wed Aug 10 15:28:15 2022 
+#> Date of summary: Wed Aug 10 15:28:15 2022 
+#> 
+#> Equations:
+#> d_parent/dt = - ((k1 * g * exp(-k1 * time) + k2 * (1 - g) * exp(-k2 *
+#>            time)) / (g * exp(-k1 * time) + (1 - g) * exp(-k2 * time)))
+#>            * parent
+#> d_m1/dt = + f_parent_to_m1 * ((k1 * g * exp(-k1 * time) + k2 * (1 - g)
+#>            * exp(-k2 * time)) / (g * exp(-k1 * time) + (1 - g) *
+#>            exp(-k2 * time))) * parent - k_m1 * m1
+#> 
+#> Data:
+#> 171 observations of 2 variable(s) grouped in 5 datasets
+#> 
+#> Model predictions using solution type analytical 
+#> 
+#> Fitted in 27.674 s
+#> Using 300, 100 iterations and 10 chains
+#> 
+#> Variance model: Two-component variance function 
+#> 
+#> Mean of starting values for individual parameters:
+#>        parent_0        log_k_m1 f_parent_qlogis          log_k1          log_k2 
+#>       101.65645        -4.05368        -0.94311        -2.35943        -4.07006 
+#>        g_qlogis 
+#>        -0.01132 
+#> 
+#> Fixed degradation parameter values:
+#> None
+#> 
+#> Results:
+#> 
+#> Likelihood computed by importance sampling
+#>     AIC   BIC logLik
+#>   825.6 821.3 -401.8
+#> 
+#> Optimised parameters:
+#>                     est.   lower    upper
+#> parent_0        100.4624 97.5484 103.3763
+#> log_k_m1         -4.0576 -4.1504  -3.9647
+#> f_parent_qlogis  -0.9136 -1.3240  -0.5031
+#> log_k1           -2.8822 -3.6302  -2.1341
+#> log_k2           -3.6307 -4.3226  -2.9388
+#> g_qlogis          0.0519 -0.7783   0.8821
+#> 
+#> Correlation: 
+#>                 parnt_0 lg_k_m1 f_prnt_ log_k1  log_k2 
+#> log_k_m1        -0.4102                                
+#> f_parent_qlogis -0.2113  0.2439                        
+#> log_k1           0.1308 -0.1305 -0.0504                
+#> log_k2          -0.0383  0.0592  0.0151  0.0001        
+#> g_qlogis        -0.0029 -0.0118  0.0131 -0.2547 -0.1942
+#> 
+#> Random effects:
+#>                      est.  lower  upper
+#> SD.f_parent_qlogis 0.4471 0.1658 0.7284
+#> SD.log_k1          0.7929 0.2769 1.3090
+#> SD.log_k2          0.7566 0.2694 1.2439
+#> 
+#> Variance model:
+#>        est.   lower   upper
+#> a.1 0.88751 0.70273 1.07228
+#> b.1 0.08328 0.06781 0.09875
+#> 
+#> Backtransformed parameters:
+#>                     est.    lower     upper
+#> parent_0       100.46239 97.54845 103.37634
+#> k_m1             0.01729  0.01576   0.01897
+#> f_parent_to_m1   0.28627  0.21015   0.37681
+#> k1               0.05601  0.02651   0.11835
+#> k2               0.02650  0.01327   0.05293
+#> g                0.51297  0.31468   0.70726
+#> 
+#> Resulting formation fractions:
+#>                 ff
+#> parent_m1   0.2863
+#> parent_sink 0.7137
+#> 
+#> Estimated disappearance times:
+#>         DT50   DT90 DT50back DT50_k1 DT50_k2
+#> parent 17.44  65.15    19.61   12.37   26.16
+#> m1     40.09 133.17       NA      NA      NA
+#> 
+#> Data:
+#>    ds   name time observed  predicted   residual    std standardized
+#>  ds 1 parent    0     89.8  1.005e+02 -10.662393 8.4135    -1.267301
+#>  ds 1 parent    0    104.1  1.005e+02   3.637607 8.4135     0.432355
+#>  ds 1 parent    1     88.7  9.576e+01  -7.063498 8.0244    -0.880249
+#>  ds 1 parent    1     95.5  9.576e+01  -0.263498 8.0244    -0.032837
+#>  ds 1 parent    3     81.8  8.717e+01  -5.369491 7.3135    -0.734185
+#>  ds 1 parent    3     94.5  8.717e+01   7.330509 7.3135     1.002320
+#>  ds 1 parent    7     71.5  7.274e+01  -1.238672 6.1224    -0.202319
+#>  ds 1 parent    7     70.3  7.274e+01  -2.438672 6.1224    -0.398322
+#>  ds 1 parent   14     54.2  5.418e+01   0.022691 4.5984     0.004935
+#>  ds 1 parent   14     49.6  5.418e+01  -4.577309 4.5984    -0.995423
+#>  ds 1 parent   28     31.5  3.241e+01  -0.914545 2.8416    -0.321837
+#>  ds 1 parent   28     28.8  3.241e+01  -3.614545 2.8416    -1.271993
+#>  ds 1 parent   60     12.1  1.283e+01  -0.730904 1.3891    -0.526186
+#>  ds 1 parent   60     13.6  1.283e+01   0.769096 1.3891     0.553681
+#>  ds 1 parent   90      6.2  6.128e+00   0.071981 1.0238     0.070309
+#>  ds 1 parent   90      8.3  6.128e+00   2.171981 1.0238     2.121538
+#>  ds 1 parent  120      2.2  3.022e+00  -0.822164 0.9225    -0.891230
+#>  ds 1 parent  120      2.4  3.022e+00  -0.622164 0.9225    -0.674429
+#>  ds 1     m1    1      0.3  1.163e+00  -0.863423 0.8928    -0.967116
+#>  ds 1     m1    1      0.2  1.163e+00  -0.963423 0.8928    -1.079126
+#>  ds 1     m1    3      2.2  3.233e+00  -1.032930 0.9274    -1.113734
+#>  ds 1     m1    3      3.0  3.233e+00  -0.232930 0.9274    -0.251152
+#>  ds 1     m1    7      6.5  6.495e+00   0.005314 1.0393     0.005113
+#>  ds 1     m1    7      5.0  6.495e+00  -1.494686 1.0393    -1.438116
+#>  ds 1     m1   14     10.2  1.010e+01   0.096372 1.2230     0.078801
+#>  ds 1     m1   14      9.5  1.010e+01  -0.603628 1.2230    -0.493572
+#>  ds 1     m1   28     12.2  1.269e+01  -0.492073 1.3802    -0.356526
+#>  ds 1     m1   28     13.4  1.269e+01   0.707927 1.3802     0.512922
+#>  ds 1     m1   60     11.8  1.086e+01   0.944360 1.2669     0.745420
+#>  ds 1     m1   60     13.2  1.086e+01   2.344360 1.2669     1.850494
+#>  ds 1     m1   90      6.6  7.723e+00  -1.123088 1.0961    -1.024658
+#>  ds 1     m1   90      9.3  7.723e+00   1.576912 1.0961     1.438708
+#>  ds 1     m1  120      3.5  5.184e+00  -1.683936 0.9869    -1.706219
+#>  ds 1     m1  120      5.4  5.184e+00   0.216064 0.9869     0.218923
+#>  ds 2 parent    0    118.0  1.005e+02  17.537607 8.4135     2.084469
+#>  ds 2 parent    0     99.8  1.005e+02  -0.662393 8.4135    -0.078730
+#>  ds 2 parent    1     90.2  9.566e+01  -5.456414 8.0156    -0.680727
+#>  ds 2 parent    1     94.6  9.566e+01  -1.056414 8.0156    -0.131795
+#>  ds 2 parent    3     96.1  8.702e+01   9.082833 7.3009     1.244062
+#>  ds 2 parent    3     78.4  8.702e+01  -8.617167 7.3009    -1.180281
+#>  ds 2 parent    7     77.9  7.298e+01   4.919834 6.1423     0.800981
+#>  ds 2 parent    7     77.7  7.298e+01   4.719834 6.1423     0.768420
+#>  ds 2 parent   14     56.0  5.588e+01   0.124003 4.7372     0.026176
+#>  ds 2 parent   14     54.7  5.588e+01  -1.175997 4.7372    -0.248245
+#>  ds 2 parent   28     36.6  3.719e+01  -0.587869 3.2217    -0.182474
+#>  ds 2 parent   28     36.8  3.719e+01  -0.387869 3.2217    -0.120394
+#>  ds 2 parent   60     22.1  2.013e+01   1.973728 1.8966     1.040673
+#>  ds 2 parent   60     24.7  2.013e+01   4.573728 1.8966     2.411556
+#>  ds 2 parent   90     12.4  1.259e+01  -0.185933 1.3734    -0.135379
+#>  ds 2 parent   90     10.8  1.259e+01  -1.785933 1.3734    -1.300347
+#>  ds 2 parent  120      6.8  7.981e+00  -1.180542 1.1088    -1.064723
+#>  ds 2 parent  120      7.9  7.981e+00  -0.080542 1.1088    -0.072640
+#>  ds 2     m1    1      1.3  1.306e+00  -0.006246 0.8941    -0.006986
+#>  ds 2     m1    3      3.7  3.589e+00   0.110879 0.9365     0.118399
+#>  ds 2     m1    3      4.7  3.589e+00   1.110879 0.9365     1.186217
+#>  ds 2     m1    7      8.1  7.062e+00   1.038045 1.0647     0.974978
+#>  ds 2     m1    7      7.9  7.062e+00   0.838045 1.0647     0.787129
+#>  ds 2     m1   14     10.1  1.065e+01  -0.553713 1.2549    -0.441227
+#>  ds 2     m1   14     10.3  1.065e+01  -0.353713 1.2549    -0.281857
+#>  ds 2     m1   28     10.7  1.284e+01  -2.144854 1.3900    -1.543111
+#>  ds 2     m1   28     12.2  1.284e+01  -0.644854 1.3900    -0.463939
+#>  ds 2     m1   60     10.7  1.082e+01  -0.115278 1.2645    -0.091165
+#>  ds 2     m1   60     12.5  1.082e+01   1.684722 1.2645     1.332337
+#>  ds 2     m1   90      9.1  8.014e+00   1.085607 1.1105     0.977610
+#>  ds 2     m1   90      7.4  8.014e+00  -0.614393 1.1105    -0.553272
+#>  ds 2     m1  120      6.1  5.736e+00   0.363593 1.0079     0.360737
+#>  ds 2     m1  120      4.5  5.736e+00  -1.236407 1.0079    -1.226697
+#>  ds 3 parent    0    106.2  1.005e+02   5.737607 8.4135     0.681955
+#>  ds 3 parent    0    106.9  1.005e+02   6.437607 8.4135     0.765155
+#>  ds 3 parent    1    107.4  9.343e+01  13.972212 7.8311     1.784188
+#>  ds 3 parent    1     96.1  9.343e+01   2.672212 7.8311     0.341229
+#>  ds 3 parent    3     79.4  8.160e+01  -2.196297 6.8531    -0.320484
+#>  ds 3 parent    3     82.6  8.160e+01   1.003703 6.8531     0.146460
+#>  ds 3 parent    7     63.9  6.464e+01  -0.737220 5.4557    -0.135129
+#>  ds 3 parent    7     62.4  6.464e+01  -2.237220 5.4557    -0.410072
+#>  ds 3 parent   14     51.0  4.772e+01   3.278433 4.0722     0.805086
+#>  ds 3 parent   14     47.1  4.772e+01  -0.621567 4.0722    -0.152638
+#>  ds 3 parent   28     36.1  3.303e+01   3.070676 2.8903     1.062400
+#>  ds 3 parent   28     36.6  3.303e+01   3.570676 2.8903     1.235391
+#>  ds 3 parent   60     20.1  1.929e+01   0.808039 1.8355     0.440235
+#>  ds 3 parent   60     19.8  1.929e+01   0.508039 1.8355     0.276789
+#>  ds 3 parent   90     11.3  1.209e+01  -0.794443 1.3425    -0.591785
+#>  ds 3 parent   90     10.7  1.209e+01  -1.394443 1.3425    -1.038728
+#>  ds 3 parent  120      8.2  7.590e+00   0.610002 1.0896     0.559843
+#>  ds 3 parent  120      7.3  7.590e+00  -0.289998 1.0896    -0.266152
+#>  ds 3     m1    0      0.8 -4.263e-14   0.800000 0.8875     0.901401
+#>  ds 3     m1    1      1.8  1.692e+00   0.107665 0.8986     0.119811
+#>  ds 3     m1    1      2.3  1.692e+00   0.607665 0.8986     0.676214
+#>  ds 3     m1    3      4.2  4.455e+00  -0.255347 0.9619    -0.265449
+#>  ds 3     m1    3      4.1  4.455e+00  -0.355347 0.9619    -0.369404
+#>  ds 3     m1    7      6.8  8.124e+00  -1.324338 1.1160    -1.186685
+#>  ds 3     m1    7     10.1  8.124e+00   1.975662 1.1160     1.770309
+#>  ds 3     m1   14     11.4  1.104e+01   0.361860 1.2778     0.283196
+#>  ds 3     m1   14     12.8  1.104e+01   1.761860 1.2778     1.378852
+#>  ds 3     m1   28     11.5  1.177e+01  -0.272554 1.3225    -0.206097
+#>  ds 3     m1   28     10.6  1.177e+01  -1.172554 1.3225    -0.886648
+#>  ds 3     m1   60      7.5  9.242e+00  -1.741667 1.1747    -1.482591
+#>  ds 3     m1   60      8.6  9.242e+00  -0.641667 1.1747    -0.546218
+#>  ds 3     m1   90      7.3  6.837e+00   0.463318 1.0544     0.439398
+#>  ds 3     m1   90      8.1  6.837e+00   1.263318 1.0544     1.198095
+#>  ds 3     m1  120      5.3  4.906e+00   0.394322 0.9770     0.403595
+#>  ds 3     m1  120      3.8  4.906e+00  -1.105678 0.9770    -1.131677
+#>  ds 4 parent    0    104.7  1.005e+02   4.237607 8.4135     0.503670
+#>  ds 4 parent    0     88.3  1.005e+02 -12.162393 8.4135    -1.445587
+#>  ds 4 parent    1     94.2  9.723e+01  -3.029220 8.1458    -0.371877
+#>  ds 4 parent    1     94.6  9.723e+01  -2.629220 8.1458    -0.322772
+#>  ds 4 parent    3     78.1  9.114e+01 -13.041804 7.6420    -1.706592
+#>  ds 4 parent    3     96.5  9.114e+01   5.358196 7.6420     0.701150
+#>  ds 4 parent    7     76.2  8.033e+01  -4.133084 6.7488    -0.612421
+#>  ds 4 parent    7     77.8  8.033e+01  -2.533084 6.7488    -0.375340
+#>  ds 4 parent   14     70.8  6.504e+01   5.757987 5.4889     1.049017
+#>  ds 4 parent   14     67.3  6.504e+01   2.257987 5.4889     0.411371
+#>  ds 4 parent   28     43.1  4.418e+01  -1.080806 3.7849    -0.285557
+#>  ds 4 parent   28     45.1  4.418e+01   0.919194 3.7849     0.242858
+#>  ds 4 parent   60     21.3  2.110e+01   0.200596 1.9686     0.101899
+#>  ds 4 parent   60     23.5  2.110e+01   2.400596 1.9686     1.219459
+#>  ds 4 parent   90     11.8  1.183e+01  -0.034206 1.3263    -0.025791
+#>  ds 4 parent   90     12.1  1.183e+01   0.265794 1.3263     0.200408
+#>  ds 4 parent  120      7.0  6.985e+00   0.014647 1.0612     0.013803
+#>  ds 4 parent  120      6.2  6.985e+00  -0.785353 1.0612    -0.740078
+#>  ds 4     m1    0      1.6 -1.705e-13   1.600000 0.8875     1.802801
+#>  ds 4     m1    1      0.9  6.803e-01   0.219655 0.8893     0.246994
+#>  ds 4     m1    3      3.7  1.927e+00   1.773027 0.9019     1.965880
+#>  ds 4     m1    3      2.0  1.927e+00   0.073027 0.9019     0.080970
+#>  ds 4     m1    7      3.6  4.013e+00  -0.412926 0.9483    -0.435417
+#>  ds 4     m1    7      3.8  4.013e+00  -0.212926 0.9483    -0.224523
+#>  ds 4     m1   14      7.1  6.604e+00   0.495843 1.0441     0.474896
+#>  ds 4     m1   14      6.6  6.604e+00  -0.004157 1.0441    -0.003981
+#>  ds 4     m1   28      9.5  9.077e+00   0.422700 1.1658     0.362576
+#>  ds 4     m1   28      9.3  9.077e+00   0.222700 1.1658     0.191024
+#>  ds 4     m1   60      8.3  8.818e+00  -0.518498 1.1520    -0.450099
+#>  ds 4     m1   60      9.0  8.818e+00   0.181502 1.1520     0.157559
+#>  ds 4     m1   90      6.6  6.738e+00  -0.137785 1.0500    -0.131222
+#>  ds 4     m1   90      7.7  6.738e+00   0.962215 1.0500     0.916383
+#>  ds 4     m1  120      3.7  4.794e+00  -1.093754 0.9732    -1.123914
+#>  ds 4     m1  120      3.5  4.794e+00  -1.293754 0.9732    -1.329429
+#>  ds 5 parent    0    110.4  1.005e+02   9.937607 8.4135     1.181155
+#>  ds 5 parent    0    112.1  1.005e+02  11.637607 8.4135     1.383212
+#>  ds 5 parent    1     93.5  9.372e+01  -0.215694 7.8550    -0.027460
+#>  ds 5 parent    1     91.0  9.372e+01  -2.715694 7.8550    -0.345730
+#>  ds 5 parent    3     71.0  8.226e+01 -11.257156 6.9076    -1.629667
+#>  ds 5 parent    3     89.7  8.226e+01   7.442844 6.9076     1.077480
+#>  ds 5 parent    7     60.4  6.553e+01  -5.128464 5.5289    -0.927571
+#>  ds 5 parent    7     59.1  6.553e+01  -6.428464 5.5289    -1.162699
+#>  ds 5 parent   14     56.5  4.835e+01   8.146351 4.1235     1.975572
+#>  ds 5 parent   14     47.0  4.835e+01  -1.353649 4.1235    -0.328273
+#>  ds 5 parent   28     30.2  3.300e+01  -2.803303 2.8883    -0.970586
+#>  ds 5 parent   28     23.9  3.300e+01  -9.103303 2.8883    -3.151832
+#>  ds 5 parent   60     17.0  1.891e+01  -1.905909 1.8074    -1.054506
+#>  ds 5 parent   60     18.7  1.891e+01  -0.205909 1.8074    -0.113926
+#>  ds 5 parent   90     11.3  1.172e+01  -0.423434 1.3194    -0.320923
+#>  ds 5 parent   90     11.9  1.172e+01   0.176566 1.3194     0.133820
+#>  ds 5 parent  120      9.0  7.281e+00   1.719138 1.0749     1.599402
+#>  ds 5 parent  120      8.1  7.281e+00   0.819138 1.0749     0.762086
+#>  ds 5     m1    0      0.7 -2.842e-13   0.700000 0.8875     0.788726
+#>  ds 5     m1    1      3.0  3.252e+00  -0.252227 0.9279    -0.271821
+#>  ds 5     m1    1      2.6  3.252e+00  -0.652227 0.9279    -0.702895
+#>  ds 5     m1    3      5.1  8.615e+00  -3.515326 1.1413    -3.080237
+#>  ds 5     m1    3      7.5  8.615e+00  -1.115326 1.1413    -0.977283
+#>  ds 5     m1    7     16.5  1.588e+01   0.619041 1.5928     0.388661
+#>  ds 5     m1    7     19.0  1.588e+01   3.119041 1.5928     1.958272
+#>  ds 5     m1   14     22.9  2.189e+01   1.014705 2.0272     0.500543
+#>  ds 5     m1   14     23.2  2.189e+01   1.314705 2.0272     0.648529
+#>  ds 5     m1   28     22.2  2.369e+01  -1.487604 2.1632    -0.687701
+#>  ds 5     m1   28     24.4  2.369e+01   0.712396 2.1632     0.329332
+#>  ds 5     m1   60     15.5  1.869e+01  -3.193942 1.7920    -1.782295
+#>  ds 5     m1   60     19.8  1.869e+01   1.106058 1.7920     0.617206
+#>  ds 5     m1   90     14.9  1.380e+01   1.103454 1.4518     0.760041
+#>  ds 5     m1   90     14.2  1.380e+01   0.403454 1.4518     0.277892
+#>  ds 5     m1  120     10.9  9.864e+00   1.035963 1.2093     0.856637
+#>  ds 5     m1  120     10.4  9.864e+00   0.535963 1.2093     0.443187
+# }
+
    @@ -213,7 +561,7 @@ saemix authors for the parts inherited from saemix.

    -

    Site built with pkgdown 2.0.2.

    +

    Site built with pkgdown 2.0.6.

    -- cgit v1.2.1