From 0b98c459c30a0629a728acf6b311de035c55fb64 Mon Sep 17 00:00:00 2001 From: Johannes Ranke Date: Wed, 18 Jul 2018 15:18:30 +0200 Subject: Correct references to the Rocke and Lorenzato model Rename 'sigma_rl' to 'sigma_twocomp' as the Rocke and Lorenzato model assumes lognormal distribution for large y. Rebuild static documentation. --- docs/reference/synthetic_data_for_UBA.html | 12 +++++++++--- 1 file changed, 9 insertions(+), 3 deletions(-) (limited to 'docs/reference/synthetic_data_for_UBA.html') diff --git a/docs/reference/synthetic_data_for_UBA.html b/docs/reference/synthetic_data_for_UBA.html index 6e0ac227..9d9404e5 100644 --- a/docs/reference/synthetic_data_for_UBA.html +++ b/docs/reference/synthetic_data_for_UBA.html @@ -39,7 +39,10 @@ Variance component 'a' is based on a normal distribution with standard deviation Variance component 'b' is also based on a normal distribution, but with a standard deviation of 7. Variance component 'c' is based on the error model from Rocke and Lorenzato (1995), with the minimum standard deviation (for small y values) of 0.5, and a proportionality constant of 0.07 - for the increase of the standard deviation with y. + for the increase of the standard deviation with y. Note that this is a simplified version + of the error model proposed by Rocke and Lorenzato (1995), as in their model the error of the + measured values approximates lognormal distribution for high values, whereas we are using + normally distributed error components all along. Initial concentrations for metabolites and all values where adding the variance component resulted in a value below the assumed limit of detection of 0.1 were set to NA. As an example, the first dataset has the title SFO_lin_a and is based on the SFO model @@ -73,7 +76,7 @@ Compare also the code in the example section to see the degradation models." /> mkin - 0.9.47.1 + 0.9.47.2 @@ -142,7 +145,10 @@ Compare also the code in the example section to see the degradation models." /> Variance component 'b' is also based on a normal distribution, but with a standard deviation of 7. Variance component 'c' is based on the error model from Rocke and Lorenzato (1995), with the minimum standard deviation (for small y values) of 0.5, and a proportionality constant of 0.07 - for the increase of the standard deviation with y.

+ for the increase of the standard deviation with y. Note that this is a simplified version + of the error model proposed by Rocke and Lorenzato (1995), as in their model the error of the + measured values approximates lognormal distribution for high values, whereas we are using + normally distributed error components all along.

Initial concentrations for metabolites and all values where adding the variance component resulted in a value below the assumed limit of detection of 0.1 were set to NA.

As an example, the first dataset has the title SFO_lin_a and is based on the SFO model -- cgit v1.2.1