From 556598ba543cf655cdc0a6995cc579327f9540ad Mon Sep 17 00:00:00 2001 From: Johannes Ranke Date: Wed, 9 Dec 2015 10:20:50 +0100 Subject: Static documentation rebuilt by staticdocs::build_site() --- inst/web/index.html | 26 +++++--------------------- 1 file changed, 5 insertions(+), 21 deletions(-) (limited to 'inst/web/index.html') diff --git a/inst/web/index.html b/inst/web/index.html index bb85e72f..17c5ba6e 100644 --- a/inst/web/index.html +++ b/inst/web/index.html @@ -66,15 +66,6 @@ if several compartments are involved.

install.packages("mkin")
-

If looking for the latest features, you can install directly from -github, e.g. using the devtools package. -Using quick = TRUE skips docs, multiple-architecture builds, demos, and -vignettes, to make installation as fast and painless as possible.

- -
require(devtools)
-install_github("jranke/mkin", quick = TRUE)
-
-

Background

In the regulatory evaluation of chemical substances like plant protection @@ -108,7 +99,7 @@ reversible binding (SFORB) model, which will automatically create two latent state variables for the observed variable.

  • As of version 0.9-39, fitting of several models to several datasets, optionally in parallel, is supported, see for example -plot.mmkin
    • +plot.mmkin.
  • Model solution (forward modelling) in the function mkinpredict is performed either using the analytical solution for the case of @@ -121,10 +112,6 @@ generated C code, see
    The autogeneration of C code was inspired by the ccSolve package. Thanks to Karline Soetaert for her work on that.
    • -
  • Model optimisation with -mkinfit -internally using the modFit function from the FME package, -but using the Port routine nlminb per default.
  • By default, kinetic rate constants and kinetic formation fractions are transformed internally using transform_odeparms @@ -152,9 +139,7 @@ as in KinGUII and CAKE (see below). Simply add the argument componenent for each of the observed variables will be optimised in a second stage after the primary optimisation algorithm has converged.
  • When a metabolite decline phase is not described well by SFO kinetics, -either IORE kinetics (often producing failures of the integration algorithm) -or SFORB kinetics (working nicely) can be used for the metabolite, adding one -respectively two parameters to the system.
    • +SFORB kinetics can be used for the metabolite.

    GUI

    @@ -171,9 +156,8 @@ and one for the git

    Credits and historical remarks

    mkin would not be possible without the underlying software stack consisting -of R and the packages deSolve, -minpack.lm and -FME, to say the least.

    +of R and the packages deSolve +and FME, to say the least.

    It could not have been written without me being introduced to regulatory fate modelling of pesticides by Adrian Gurney during my time at Harlan Laboratories @@ -187,7 +171,7 @@ as detailed in their guidance document from 2006, slightly updated in 2011 and BayerCropScience, which is based on the MatLab runtime environment.

    The companion package -kinfit was +kinfit (now deprecated) was started in 2008 and first published on CRAN on 01 May 2010.

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