From d267b8c116f78ee9b7b4d76c9ddb7b8950a127b4 Mon Sep 17 00:00:00 2001 From: jranke Date: Thu, 20 Sep 2012 11:02:28 +0000 Subject: Some updates of the mkin vignette Added the kinfit vignette file to the repository git-svn-id: svn+ssh://svn.r-forge.r-project.org/svnroot/kinfit/pkg/mkin@57 edb9625f-4e0d-4859-8d74-9fd3b1da38cb --- vignettes/mkin.Rnw | 12 ++++++------ 1 file changed, 6 insertions(+), 6 deletions(-) (limited to 'vignettes/mkin.Rnw') diff --git a/vignettes/mkin.Rnw b/vignettes/mkin.Rnw index 9110ad7f..2f79cc56 100644 --- a/vignettes/mkin.Rnw +++ b/vignettes/mkin.Rnw @@ -60,10 +60,10 @@ metabolites. Many approaches are possible regarding the evaluation of chemical degradation data. The \Rpackage{kinfit} package \citep{pkg:kinfit} in \RR{} -\citep{rcore2010} implements the approach recommended in the kinetics report +\citep{rcore2012} implements the approach recommended in the kinetics report provided by the FOrum for Co-ordination of pesticide fate models and their -USe \citep{FOCUS2006} for simple data series for one parent compound in one -compartment. +USe \citep{FOCUS2006, FOCUSkinetics2011} for simple data series for one parent +compound in one compartment. The \Rpackage{mkin} package \citep{pkg:mkin} extends this approach to data series with metabolites and more than one compartment and includes the possibility @@ -131,14 +131,14 @@ differential equations. In these cases, a coefficient matrix is also returned. Other models that include time on the right-hand side of the differential equation are the first-order multi-compartment (FOMC) model and the -Hockey-Stick (HS) model. At present, only the FOMC model can only be used, and -only for the parent compound. +Hockey-Stick (HS) model. At present, these models can only be used only for the +parent compound. \subsection{Fitting the model} Then the model parameters should be fitted to the data. The function \Robject{mkinfit} internally creates a cost function using \Robject{modCost} -from the \Rpackage{FME} package and the produces a fit using \Robject{modFit} +from the \Rpackage{FME} package and then produces a fit using \Robject{modFit} from the same package. In cases of linear first-order differential equations, the solution used for calculating the cost function is based on the fundamental system of the coefficient matrix, as proposed by -- cgit v1.2.1