#' Create an nlme model for an mmkin row object #' #' This functions sets up a nonlinear mixed effects model for an mmkin row #' object. An mmkin row object is essentially a list of mkinfit objects that #' have been obtained by fitting the same model to a list of datasets. #' #' @param model An \code{\link{mmkin}} row object. #' @param data Ignored, data are taken from the mmkin model #' @param fixed Ignored, all degradation parameters fitted in the #' mmkin model are used as fixed parameters #' @param random If not specified, all fixed effects are complemented #' with uncorrelated random effects #' @param groups See the documentation of nlme #' @param start If not specified, mean values of the fitted degradation #' parameters taken from the mmkin object are used #' @param correlation See the documentation of nlme #' @param weights passed to nlme #' @param subset passed to nlme #' @param method passed to nlme #' @param na.action passed to nlme #' @param naPattern passed to nlme #' @param control passed to nlme #' @param verbose passed to nlme #' @importFrom stats na.fail #' @return Upon success, a fitted nlme.mmkin object, which is #' an nlme object with additional elements #' @export #' @seealso \code{\link{nlme_function}} #' @examples #' ds <- lapply(experimental_data_for_UBA_2019[6:10], #' function(x) subset(x$data[c("name", "time", "value")], name == "parent")) #' f <- mmkin("SFO", ds, quiet = TRUE, cores = 1) #' library(nlme) #' f_nlme <- nlme(f) #' nlme(f, random = parent_0 ~ 1) #' f_nlme <- nlme(f, start = c(parent_0 = 100, log_k_parent_sink = 0.1)) #' update(f_nlme, random = parent_0 ~ 1) # Code inspired by nlme.nlsList nlme.mmkin <- function(model, data = sys.frame(sys.parent()), fixed, random = fixed, groups, start, correlation = NULL, weights = NULL, subset, method = c("ML", "REML"), na.action = na.fail, naPattern, control = list(), verbose= FALSE) { if (nrow(model) > 1) stop("Only row objects allowed") thisCall <- as.list(match.call())[-1] # warn in case of use of arguments that are overriden if (any(!is.na(match(names(thisCall), c("fixed", "data"))))) { warning("'nlme.mmkin' will redefine 'fixed' and 'data'") } deg_func <- nlme_function(model) assign("deg_func", deg_func, parent.frame()) # specify the model formula this_model_text <- paste0("value ~ deg_func(", paste(names(formals(deg_func)), collapse = ", "), ")") this_model <- eval(parse(text = this_model_text)) thisCall[["model"]] <- this_model mean_dp <- mean_degparms(model) dp_names <- names(mean_dp) thisCall[["data"]] <- nlme_data(model) if (missing(start)) { thisCall[["start"]] <- mean_dp } thisCall[["fixed"]] <- lapply(as.list(dp_names), function(el) eval(parse(text = paste(el, 1, sep = "~")))) if (missing(random)) { thisCall[["random"]] <- pdDiag(thisCall[["fixed"]]) } val <- do.call("nlme.formula", thisCall) return(val) class(val) <- c("nlme.mmkin", "nlme", "lme") }