ℹ Loading mkin
Loading required package: parallel
ℹ Testing mkin
✔ | F W S  OK | Context
✔ |         5 | AIC calculation
✔ |         5 | Analytical solutions for coupled models [3.2s]
✔ |         5 | Calculation of Akaike weights
✔ |         3 | Export dataset for reading into CAKE
✔ |        12 | Confidence intervals and p-values [1.0s]
✔ |     1  12 | Dimethenamid data from 2018 [32.1s]
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Skip (test_dmta.R:98:3): Different backends get consistent results for SFO-SFO3+, dimethenamid data
Reason: Fitting this ODE model with saemix takes about 15 minutes on my system
────────────────────────────────────────────────────────────────────────────────
✔ |        14 | Error model fitting [4.8s]
✔ |         5 | Time step normalisation
✔ |         4 | Calculation of FOCUS chi2 error levels [0.6s]
✔ |        14 | Results for FOCUS D established in expertise for UBA (Ranke 2014) [0.8s]
✔ |         4 | Test fitting the decline of metabolites from their maximum [0.3s]
✔ |         1 | Fitting the logistic model [0.2s]
✔ |     1  12 | Nonlinear mixed-effects models [0.2s]
────────────────────────────────────────────────────────────────────────────────
Skip (test_mixed.R:68:3): saemix results are reproducible for biphasic fits
Reason: Fitting with saemix takes around 10 minutes when using deSolve
────────────────────────────────────────────────────────────────────────────────
✔ |         3 | Test dataset classes mkinds and mkindsg
✔ |        10 | Special cases of mkinfit calls [0.4s]
✔ |         3 | mkinfit features [0.7s]
✔ |         8 | mkinmod model generation and printing [0.2s]
✔ |         3 | Model predictions with mkinpredict [0.4s]
✔ |        16 | Evaluations according to 2015 NAFTA guidance [1.5s]
✔ |         9 | Nonlinear mixed-effects models with nlme [8.1s]
✖ | 2      14 | Plotting [10.5s]
────────────────────────────────────────────────────────────────────────────────
Failure (test_plot.R:56:3): Plotting mkinfit, mmkin and mixed model objects is reproducible
Snapshot of `testcase` to 'plot/mixed-model-fit-for-nlme-object.svg' has changed
Run `testthat::snapshot_review('plot/')` to review changes
Backtrace:
 1. vdiffr::expect_doppelganger(...)
      at test_plot.R:56:2
 3. testthat::expect_snapshot_file(...)

Failure (test_plot.R:64:3): Plotting mkinfit, mmkin and mixed model objects is reproducible
Snapshot of `testcase` to 'plot/mixed-model-fit-for-saem-object-with-mkin-transformations.svg' has changed
Run `testthat::snapshot_review('plot/')` to review changes
Backtrace:
 1. vdiffr::expect_doppelganger(...)
      at test_plot.R:64:2
 3. testthat::expect_snapshot_file(...)
────────────────────────────────────────────────────────────────────────────────
✔ |         4 | Residuals extracted from mkinfit models
✔ |        25 | saemix parent models [171.7s]
✔ |         2 | Complex test case from Schaefer et al. (2007) Piacenza paper [1.3s]
✔ |         7 | Fitting the SFORB model [3.6s]
✔ |         1 | Summaries of old mkinfit objects
✔ |         4 | Summary [0.1s]
✔ |         4 | Results for synthetic data established in expertise for UBA (Ranke 2014) [2.1s]
✔ |         9 | Hypothesis tests [7.7s]
✔ |         4 | Calculation of maximum time weighted average concentrations (TWAs) [2.3s]

══ Results ═════════════════════════════════════════════════════════════════════
Duration: 254.3 s

── Skipped tests  ──────────────────────────────────────────────────────────────
• Fitting this ODE model with saemix takes about 15 minutes on my system (1)
• Fitting with saemix takes around 10 minutes when using deSolve (1)

[ FAIL 2 | WARN 0 | SKIP 2 | PASS 222 ]