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diff --git a/chm/00Index.html b/chm/00Index.html
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@@ -1,28 +0,0 @@
-<html><head><title>Dose-response data evaluation</title>
-<link rel="stylesheet" type="text/css" href="Rchm.css">
-</head><body>
-<h1>Dose-response data evaluation
-<img class="toplogo" src="logo.jpg" alt="[R logo]"></h1>
-
-<hr>
-
-<object type="application/x-oleobject" classid="clsid:1e2a7bd0-dab9-11d0-b93a-00c04fc99f9e">
-<param name="keyword" value=".. contents">
-</object>
-
-<h2>Help pages for package `drfit' version 0.03-9</h2>
-
-
-<table width="100%">
-<tr><td width="25%"><a href="antifoul.html">antifoul</a></td>
-<td>Dose-Response data for TBT and Zink Pyrithione in IPC-81 cells</td></tr>
-<tr><td width="25%"><a href="checkplate.html">checkplate</a></td>
-<td>Check raw data from a specified microtiter plate</td></tr>
-<tr><td width="25%"><a href="drdata.html">drdata</a></td>
-<td>Get dose-response data</td></tr>
-<tr><td width="25%"><a href="drfit.html">drfit</a></td>
-<td>Fit dose-response models</td></tr>
-<tr><td width="25%"><a href="drplot.html">drplot</a></td>
-<td>Plot dose-response models</td></tr>
-</table>
-</body></html>
diff --git a/chm/Rchm.css b/chm/Rchm.css
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-BODY{		background: white;
-		color: black }
-
-A:link{         background: white;
-                color: blue }
-A:visited{	background: white;
-		color: rgb(50%, 0%, 50%) }
-
-H1{		background: white;
-		color: rgb(55%, 55%, 55%);
-		font-family: monospace;
-		font-size: large;
-		text-align: center }
-
-H2{		background: white;
-		color: rgb(0%, 0%, 100%);
-		font-family: monospace;
-		text-align: center }
-
-H3{		background: white;
-		color: rgb(40%, 40%, 40%);
-		font-family: monospace }
-
-IMG.toplogo{	vertical-align: middle }
-
diff --git a/chm/antifoul.html b/chm/antifoul.html
deleted file mode 100644
index 810c5e9..0000000
--- a/chm/antifoul.html
+++ /dev/null
@@ -1,49 +0,0 @@
-<html><head><title>Dose-Response data for TBT and Zink Pyrithione in IPC-81 cells</title>
-<link rel="stylesheet" type="text/css" href="Rchm.css">
-</head>
-<body>
-
-<table width="100%"><tr><td>antifoul(drfit)</td><td align="right">R Documentation</td></tr></table><object type="application/x-oleobject" classid="clsid:1e2a7bd0-dab9-11d0-b93a-00c04fc99f9e">
-<param name="keyword" value="R:   antifoul">
-<param name="keyword" value=" Dose-Response data for TBT and Zink Pyrithione in IPC-81 cells">
-</object>
-
-
-<h2>Dose-Response data for TBT and Zink Pyrithione in IPC-81 cells</h2>
-
-
-<h3>Description</h3>
-
-<p>
-This data set shows the response of the rat leukaemic cell line IPC-81 to 
-dilution series of tributyltin chloride (TBT) and Zink Pyrithione as retrieved
-from the "cytotox" database of the UFT Department of Bioorganic Chemistry on 
-February 25, 2004
-</p>
-
-
-<h3>Usage</h3>
-
-<pre>data(antifoul)</pre>
-
-
-<h3>Format</h3>
-
-<p>
-A dataframe containing 135 and 81 data points for concentrations and responses
-for TBT and Zink Pyrithione, respectively. Additional data from the database is 
-also present.
-</p>
-
-
-<h3>Source</h3>
-
-<p>
-<a href="http://www.uft.uni-bremen.de/chemie">http://www.uft.uni-bremen.de/chemie</a>
-</p>
-
-
-
-<hr><div align="center"><a href="00Index.html">[Package Contents]</a></div>
-
-</body></html>
diff --git a/chm/checkplate.html b/chm/checkplate.html
deleted file mode 100755
index d545656..0000000
--- a/chm/checkplate.html
+++ /dev/null
@@ -1,68 +0,0 @@
-<html><head><title>Check raw data from a specified microtiter plate</title>
-<link rel="stylesheet" type="text/css" href="Rchm.css">
-</head>
-<body>
-
-<table width="100%"><tr><td>checkplate(drfit)</td><td align="right">R Documentation</td></tr></table><object type="application/x-oleobject" classid="clsid:1e2a7bd0-dab9-11d0-b93a-00c04fc99f9e">
-<param name="keyword" value="R:   checkplate">
-<param name="keyword" value=" Check raw data from a specified microtiter plate">
-</object>
-
-
-<h2>Check raw data from a specified microtiter plate</h2>
-
-
-<h3>Description</h3>
-
-<p>
-Report metadata from a specified microtiter plate from a specified database, box 
-plot positive and negative (blind) controls, and show the response data on the 
-plate.
-</p>
-
-
-<h3>Usage</h3>
-
-<pre>
-  checkplate(plate,db="cytotox")
-</pre>
-
-
-<h3>Arguments</h3>
-
-<table summary="R argblock">
-<tr valign="top"><td><code>plate</code></td>
-<td>
-The number of the plate identifying it within the database.</td></tr>
-<tr valign="top"><td><code>db</code></td>
-<td>
-The database to be used. Currently only "cytotox" of the UFT Department of
-Bioorganic Chemistry is supported.</td></tr>
-</table>
-
-<h3>Value</h3>
-
-<p>
-The function lists a report and shows two graphs.</p>
-
-<h3>Author(s)</h3>
-
-<p>
-Johannes Ranke 
-<a href="mailto:jranke@uni-bremen.de">jranke@uni-bremen.de</a> 
-<a href="http://www.uft.uni-bremen.de/chemie/ranke">http://www.uft.uni-bremen.de/chemie/ranke</a>
-</p>
-
-
-<h3>Examples</h3>
-
-<pre>
-# Check plate number 1 in the cytotox database
-## Not run: data &lt;- checkplate(1)
-</pre>
-
-
-
-<hr><div align="center"><a href="00Index.html">[Package Contents]</a></div>
-
-</body></html>
diff --git a/chm/drdata.html b/chm/drdata.html
deleted file mode 100644
index a2ef9d9..0000000
--- a/chm/drdata.html
+++ /dev/null
@@ -1,147 +0,0 @@
-<html><head><title>Get dose-response data</title>
-<link rel="stylesheet" type="text/css" href="Rchm.css">
-</head>
-<body>
-
-<table width="100%"><tr><td>drdata(drfit)</td><td align="right">R Documentation</td></tr></table><object type="application/x-oleobject" classid="clsid:1e2a7bd0-dab9-11d0-b93a-00c04fc99f9e">
-<param name="keyword" value="R:   drdata">
-<param name="keyword" value=" Get dose-response data">
-</object>
-
-
-<h2>Get dose-response data</h2>
-
-
-<h3>Description</h3>
-
-<p>
-Get dose-response data from a remote mysql server
-</p>
-
-
-<h3>Usage</h3>
-
-<pre>
-  drdata(substances, experimentator = "%", db = "cytotox", celltype = "IPC-81", 
-    whereClause = "1", ok = "'ok'")
-</pre>
-
-
-<h3>Arguments</h3>
-
-<table summary="R argblock">
-<tr valign="top"><td><code>substances</code></td>
-<td>
-A string or an array of strings with the substance names for
-which dose-response data is to be retrieved.</td></tr>
-<tr valign="top"><td><code>experimentator</code></td>
-<td>
-The name of the experimentator whose data is to be used.</td></tr>
-<tr valign="top"><td><code>db</code></td>
-<td>
-The database to be used. Currently only "cytotox" of the UFT Department of
-Bioorganic Chemistry is supported.</td></tr>
-<tr valign="top"><td><code>celltype</code></td>
-<td>
-Currently, only data for IPC-81, C6, NB4, HeLa, Jurkat and U937 are supported.</td></tr>
-<tr valign="top"><td><code>whereClause</code></td>
-<td>
-With this argument, additional conditions for the SQL query can be set, 
-e.g. "where plate != 710". The default is 1 (in SQL syntax this means TRUE).</td></tr>
-<tr valign="top"><td><code>ok</code></td>
-<td>
-With the default value "'ok'", only data that has been checked and set to "ok"
-in the database is retrieved. Another sensible argument would be "'ok','?'", in 
-order to additionally retrieve data which has not yet been checked.</td></tr>
-</table>
-
-<h3>Details</h3>
-
-<p>
-The function is currently only used for retrieving data from the
-mysql database "cytotox" of the UFT Department of Bioorganic Chemistry.
-Access to this database is limited to UFT staff.  Additionally to the
-installation of the RODBC package, it is required to set up a ODBC data
-source with the name "cytotox", using an ODBC driver for mysql, probably
-myODBC. Then, under Unix, you can use iodbc or unixodbc for setting up the
-respective data source with data source name (DSN) "cytotox". For my
-setting using unixodbc, I am using the file &lsquo;<TT>/etc/odbcinst.ini</TT>&rsquo;
-containing: 
-<table summary="Rd table">
-<tr>
-  <td align="left">[MySQL] </td>  <td align="left"> </td>  <td align="left"> </td>
-</tr>
-<tr>
-  <td align="left"> Description </td>  <td align="left"> = </td>  <td align="left"> MySQL driver for ODBC </td>
-</tr>
-<tr>
-  <td align="left"> Driver </td>  <td align="left"> = </td>  <td align="left"> /usr/local/lib/libmyodbc.so </td>
-</tr>
-<tr>
-  <td align="left"> Setup </td>  <td align="left"> = </td>  <td align="left"> /usr/lib/odbc/libodbcmyS.so </td>
-</tr>
-</table>
-<p>
-and the file &lsquo;<TT>/etc/odbc.ini</TT>&rsquo; containing:
-<table summary="Rd table">
-<tr>
-  <td align="left">[cytotox] </td>  <td align="left"> </td>  <td align="left"> </td>
-</tr>
-<tr>
-  <td align="left"> Description </td>  <td align="left"> = </td>  <td align="left"> Cytotoxicity database of the department of bioorganic chemistry, UFT Bremen </td>
-</tr>
-<tr>
-  <td align="left"> Driver </td>  <td align="left"> = </td>  <td align="left"> MySQL </td>
-</tr>
-<tr>
-  <td align="left"> Trace </td>  <td align="left"> = </td>  <td align="left"> Yes  </td>
-</tr>
-<tr>
-  <td align="left"> TraceFile </td>  <td align="left"> = </td>  <td align="left"> /tmp/odbc.log  </td>
-</tr>
-<tr>
-  <td align="left"> Database </td>  <td align="left"> = </td>  <td align="left"> cytotox  </td>
-</tr>
-<tr>
-  <td align="left"> Server </td>  <td align="left"> = </td>  <td align="left"> eckehaat  </td>
-</tr>
-<tr>
-  <td align="left"> Port </td>  <td align="left"> = </td>  <td align="left"> 3306  </td>
-</tr>
-</table>
-.
-</p>
-
-
-<h3>Value</h3>
-
-<table summary="R argblock">
-<tr valign="top"><td><code>data</code></td>
-<td>
-A data frame with a factor describing the dose levels, the numeric dose levels
-and a numeric column describing the response, as well as the entries for
-plate, experimentator, performed (date of test performance), celltype, unit
-(of the dose/concentration), and for the ok field in the database.</td></tr>
-</table>
-
-<h3>Author(s)</h3>
-
-<p>
-Johannes Ranke 
-<a href="mailto:jranke@uni-bremen.de">jranke@uni-bremen.de</a> 
-<a href="http://www.uft.uni-bremen.de/chemie/ranke">http://www.uft.uni-bremen.de/chemie/ranke</a>
-</p>
-
-
-<h3>Examples</h3>
-
-<pre>
-# Get cytotoxicity data for Tributyltin and zinc pyrithione, tested with IPC-81 cells
-## Not run: data &lt;- drdata(c("TBT","Zn Pyrithion"))
-</pre>
-
-
-
-<hr><div align="center"><a href="00Index.html">[Package Contents]</a></div>
-
-</body></html>
diff --git a/chm/drfit.chm b/chm/drfit.chm
deleted file mode 100644
index d88cbb3..0000000
--- a/chm/drfit.chm
+++ /dev/null
diff --git a/chm/drfit.hhp b/chm/drfit.hhp
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index 40a9b74..0000000
--- a/chm/drfit.hhp
+++ /dev/null
@@ -1,18 +0,0 @@
-[OPTIONS]
-Auto Index=Yes
-Contents file=drfit.toc
-Compatibility=1.1 or later
-Compiled file=drfit.chm
-Default topic=00Index.html
-Display compile progress=No
-Full-text search=Yes
-Full text search stop list file=..\..\..\gnuwin32\help\R.stp
-
-
-[FILES]
-00Index.html
-antifoul.html
-checkplate.html
-drdata.html
-drfit.html
-drplot.html
diff --git a/chm/drfit.html b/chm/drfit.html
deleted file mode 100644
index 23dd70f..0000000
--- a/chm/drfit.html
+++ /dev/null
@@ -1,99 +0,0 @@
-<html><head><title>Fit dose-response models</title>
-<link rel="stylesheet" type="text/css" href="Rchm.css">
-</head>
-<body>
-
-<table width="100%"><tr><td>drfit(drfit)</td><td align="right">R Documentation</td></tr></table><object type="application/x-oleobject" classid="clsid:1e2a7bd0-dab9-11d0-b93a-00c04fc99f9e">
-<param name="keyword" value="R:   drfit">
-<param name="keyword" value=" Fit dose-response models">
-</object>
-
-
-<h2>Fit dose-response models</h2>
-
-
-<h3>Description</h3>
-
-<p>
-Fit dose-response relationships to dose-response data and calculate
-biometric results for (eco)toxicity evaluation
-</p>
-
-
-<h3>Usage</h3>
-
-<pre>
-  drfit(data, startlogEC50 = NA, lognorm = TRUE, logis = FALSE, 
-    linearlogis = FALSE, b0 = 2, f0 = 0)
-</pre>
-
-
-<h3>Arguments</h3>
-
-<table summary="R argblock">
-<tr valign="top"><td><code>data</code></td>
-<td>
-A data frame as returned from <code><a href="drdata.html">drdata</a></code>.  The data frame has to
-contain at least a factor called "substance", a vector called "unit"
-containing the unit used for the dose, a column "response" with the
-response values of the test system normalized between 0 and 1 and a column
-"dose" with the numeric dose values. For later use of the
-<code><a href="drplot.html">drplot</a></code> function, a factor called "dosefactor" also has to be
-present, containing the dose as a factor.
-</td></tr>
-<tr valign="top"><td><code>startlogEC50</code></td>
-<td>
-Especially for the linearlogis model, a suitable log10 of the EC50 has to be given 
-by the user, since it is not correctly estimated for data showing hormesis with
-the default estimation method.</td></tr>
-<tr valign="top"><td><code>lognorm</code></td>
-<td>
-A boolean defining if cumulative density curves of normal distributions
-are fitted to the data. Default ist TRUE.</td></tr>
-<tr valign="top"><td><code>logis</code></td>
-<td>
-A boolean defining if cumulative densitiy curves of logistic distributions
-are fitted to the data. Default is FALSE.</td></tr>
-<tr valign="top"><td><code>linearlogis</code></td>
-<td>
-A boolean defining if the linear-logistic function as defined by van Ewijk and Hoekstra
-1993 is fitted to the data. Default is FALSE.</td></tr>
-<tr valign="top"><td><code>b0,f0</code></td>
-<td>
-If the linearlogistic model is fitted, b0 and f0 give the possibility to
-adapt the starting values for the parameters b and f.</td></tr>
-</table>
-
-<h3>Value</h3>
-
-<table summary="R argblock">
-<tr valign="top"><td><code>results</code></td>
-<td>
-A data frame containing at least one line for each substance. If the data did not
-show a mean response &lt; 0.5 at the highest dose level, the modeltype is set to "none".
-Every successful fit is reported in one line. Parameters of the fitted curves are only
-reported if the fitted EC50 is not higher than the highest dose.</td></tr>
-</table>
-
-<h3>Author(s)</h3>
-
-<p>
-Johannes Ranke 
-<a href="mailto:jranke@uni-bremen.de">jranke@uni-bremen.de</a> 
-<a href="http://www.uft.uni-bremen.de/chemie/ranke">http://www.uft.uni-bremen.de/chemie/ranke</a>
-</p>
-
-
-<h3>Examples</h3>
-
-<pre>
-data(antifoul)
-r &lt;- drfit(antifoul)
-format(r,digits=2)
-</pre>
-
-
-
-<hr><div align="center"><a href="00Index.html">[Package Contents]</a></div>
-
-</body></html>
diff --git a/chm/drfit.toc b/chm/drfit.toc
deleted file mode 100644
index e80cc53..0000000
--- a/chm/drfit.toc
+++ /dev/null
@@ -1,59 +0,0 @@
-<!DOCTYPE HTML PUBLIC "-//IETF//DTD HTML//EN">
-<HEAD></HEAD><HTML><BODY>
-<UL>
-<LI> <OBJECT type="text/sitemap">
-<param name="Name" value="Package drfit:  Contents">
-<param name="Local" value="00Index.html">
-</OBJECT>
-<LI> <OBJECT type="text/sitemap">
-<param name="Name" value="Package drfit:  R objects">
-</OBJECT>
-<UL>
-<LI> <OBJECT type="text/sitemap">
-<param name="Name" value="antifoul">
-<param name="Local" value="antifoul.html">
-</OBJECT>
-<LI> <OBJECT type="text/sitemap">
-<param name="Name" value="checkplate">
-<param name="Local" value="checkplate.html">
-</OBJECT>
-<LI> <OBJECT type="text/sitemap">
-<param name="Name" value="drdata">
-<param name="Local" value="drdata.html">
-</OBJECT>
-<LI> <OBJECT type="text/sitemap">
-<param name="Name" value="drfit">
-<param name="Local" value="drfit.html">
-</OBJECT>
-<LI> <OBJECT type="text/sitemap">
-<param name="Name" value="drplot">
-<param name="Local" value="drplot.html">
-</OBJECT>
-</UL>
-<LI> <OBJECT type="text/sitemap">
-<param name="Name" value="Package drfit:  Titles">
-</OBJECT>
-<UL>
-<LI> <OBJECT type="text/sitemap">
-<param name="Name" value="Check raw data from a specified microtiter plate">
-<param name="Local" value="checkplate.html">
-</OBJECT>
-<LI> <OBJECT type="text/sitemap">
-<param name="Name" value="Dose-Response data for TBT and Zink Pyrithione in IPC-81 cells">
-<param name="Local" value="antifoul.html">
-</OBJECT>
-<LI> <OBJECT type="text/sitemap">
-<param name="Name" value="Fit dose-response models">
-<param name="Local" value="drfit.html">
-</OBJECT>
-<LI> <OBJECT type="text/sitemap">
-<param name="Name" value="Get dose-response data">
-<param name="Local" value="drdata.html">
-</OBJECT>
-<LI> <OBJECT type="text/sitemap">
-<param name="Name" value="Plot dose-response models">
-<param name="Local" value="drplot.html">
-</OBJECT>
-</UL>
-</UL>
-</BODY></HTML>
diff --git a/chm/drplot.html b/chm/drplot.html
deleted file mode 100644
index 84cf12e..0000000
--- a/chm/drplot.html
+++ /dev/null
@@ -1,143 +0,0 @@
-<html><head><title>Plot dose-response models</title>
-<link rel="stylesheet" type="text/css" href="Rchm.css">
-</head>
-<body>
-
-<table width="100%"><tr><td>drplot(drfit)</td><td align="right">R Documentation</td></tr></table><object type="application/x-oleobject" classid="clsid:1e2a7bd0-dab9-11d0-b93a-00c04fc99f9e">
-<param name="keyword" value="R:   drplot">
-<param name="keyword" value=" Plot dose-response models">
-</object>
-
-
-<h2>Plot dose-response models</h2>
-
-
-<h3>Description</h3>
-
-<p>
-Produce graphics of dose-response data and dose-response relationships 
-either combined or separately, for one or more substances.
-</p>
-
-
-<h3>Usage</h3>
-
-<pre>
-  drplot(drresults, data, dtype, alpha, path, fileprefix, overlay,
-    postscript, color, datacolors, fitcolors)
-</pre>
-
-
-<h3>Arguments</h3>
-
-<table summary="R argblock">
-<tr valign="top"><td><code>drresults</code></td>
-<td>
-A data frame as returned from <code><a href="drfit.html">drfit</a></code>.
-</td></tr>
-<tr valign="top"><td><code>data</code></td>
-<td>
-A data frame as returned from <code><a href="drdata.html">drdata</a></code>.  If data is to be
-plotted, the data frame has to contain at least a factor called
-"substance", a vector called "unit" containing the unit used for the dose,
-a column "response" with the response values of the test system normalized
-between 0 and 1, a column "dose" with the numeric dose values and a factor
-called "dosefactor" containing the dose as a factor. If plotting of the data is 
-not required, data can be set to FALSE.
-</td></tr>
-<tr valign="top"><td><code>dtype</code></td>
-<td>
-A string describing if the raw data should be plotted ("raw"), or 
-an error bar should be constructed from the standard deviations of the
-responses at each dose level ("std", default value) or from the confidence
-intervals ("conf"). Of course, dtype only makes a difference, if a valid data
-object has been referenced.
-</td></tr>
-<tr valign="top"><td><code>alpha</code></td>
-<td>
-The confidence level, defaulting to 0.95, only used if dtype "conf" has been
-chosen.
-</td></tr>
-<tr valign="top"><td><code>path</code></td>
-<td>
-The path where graphic files should be put if any are produced. Defaults
-to "./" i.e. the current working directory of R.
-</td></tr>
-<tr valign="top"><td><code>fileprefix</code></td>
-<td>
-A string which will form the beginning of each filename, if graphic files are 
-created. Defaults to "drplot".
-</td></tr>
-<tr valign="top"><td><code>overlay</code></td>
-<td>
-If TRUE, all output will be put into one graph, otherwise a separate graph
-will be created for each substance. In the latter case, on-screen display
-(postscript=FALSE) only works correctly for data plots. Dose-response models
-will all be put into the last graph in this case.
-</td></tr>
-<tr valign="top"><td><code>postscript</code></td>
-<td>
-If TRUE, (a) postscript graph(s) will be created. Otherwise, graphics will be
-displayed with a screen graphics device.
-</td></tr>
-<tr valign="top"><td><code>color</code></td>
-<td>
-If TRUE, a sensible selection of colors will be attempted. If false, everything
-will be drawn in black
-</td></tr>
-<tr valign="top"><td><code>datacolors</code></td>
-<td>
-This is a vector of colors, defaulting to 1:8, used for plotting the data.
-</td></tr>
-<tr valign="top"><td><code>fitcolors</code></td>
-<td>
-Here you can specify a palette for the colors of the dose-response fits. The 
-default value is "default", which produces the default palette, if the 
-number of fits to be plotted is 8 or less. Otherwise, rainbow colors 
-will be plotted. Unless there is more than one fit per substance to be plotted,
-or the number of fits is larger than 8, the fitcolors will match the
-datacolors.
-</td></tr>
-</table>
-
-<h3>Value</h3>
-
-<table summary="R argblock">
-<tr valign="top"><td><code>results</code></td>
-<td>
-You will get plots of data and/or the fitted dose-response curves, on the
-screen and/or as postscript files, depending on the parameters.
-</td></tr>
-</table>
-
-<h3>Note</h3>
-
-<p>
-Turn off the colors if you don't like them and don't want to fiddle with
-them. Treatment of legends is quite bad. Be sure all devices are closed
-(e.g. by calling <code>dev.off()</code>) before calling <code>drplot</code> again.
-</p>
-
-
-<h3>Author(s)</h3>
-
-<p>
-Johannes Ranke 
-<a href="mailto:jranke@uni-bremen.de">jranke@uni-bremen.de</a> 
-<a href="http://www.uft.uni-bremen.de/chemie/ranke">http://www.uft.uni-bremen.de/chemie/ranke</a>
-</p>
-
-
-<h3>Examples</h3>
-
-<pre>
-data(antifoul)
-r &lt;- drfit(antifoul)
-## Not run: drplot(r,antifoul)
-</pre>
-
-
-
-<hr><div align="center"><a href="00Index.html">[Package Contents]</a></div>
-
-</body></html>
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