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      <h1> Single First-Order Reversible Binding kinetics </h1>

<div class="row">
  <div class="span8">
    <h2>Usage</h2>
    <pre><div>SFORB.solution(t, parent.0, k_12, k_21, k_1output)</div></pre>
    
    <h2>Arguments</h2>
    <dl>
      <dt>t</dt>
      <dd> Time. </dd>
      <dt>parent.0</dt>
      <dd> Starting value for the response variable at time zero. </dd>
      <dt>k_12</dt>
      <dd> Kinetic constant describing transfer from free to bound. </dd>
      <dt>k_21</dt>
      <dd> Kinetic constant describing transfer from bound to free. </dd>
      <dt>k_1output</dt>
      <dd> Kinetic constant describing degradation of the free fraction. </dd>
    </dl>
    
    <div class="Description">
      <h2>Description</h2>

      <p>Function describing the solution of the differential equations describing
  the kinetic model with first-order terms for a two-way transfer from a free
  to a bound fraction, and a first-order degradation term for the free
  fraction.  The initial condition is a defined amount in the free fraction and
  no substance in the bound fraction.</p>
  
    </div>

    <div class="Value">
      <h2>Value</h2>

      <p><dl>
  The value of the response variable, which is the sum of free and bound 
  fractions at time <code>t</code>.
</dl></p>
  
    </div>

    <div class="References">
      <h2>References</h2>

      <p>FOCUS (2006) &#147;Guidance Document on Estimating Persistence and
  Degradation Kinetics from Environmental Fate Studies on Pesticides in EU
  Registration&#148; Report of the FOCUS Work Group on Degradation Kinetics,
  EC Document Reference Sanco/10058/2005 version 2.0, 434 pp,
  <a href = 'http://focus.jrc.ec.europa.eu/dk'>http://focus.jrc.ec.europa.eu/dk</a></p>
  
    </div>
    
    <h2 id="examples">Examples</h2>
    <pre class="examples"><div class='input'>  ## Not run: plot(function(x) SFORB.solution(x, 100, 0.5, 2, 3), 0, 2)
</div></pre>
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