diff options
Diffstat (limited to 'R')
| -rw-r--r-- | R/drfit.R | 17 |
1 files changed, 9 insertions, 8 deletions
@@ -2,7 +2,8 @@ drfit <- function(data, startlogED50 = NA, chooseone=TRUE, probit = TRUE, logit = FALSE, weibull = FALSE, linlogit = FALSE, level = 0.95, linlogitWrong = NA, allWrong = NA, - s0 = 0.5, b0 = 2, f0 = 0) + ps0 = 1, ls0 = 0.5, ws0 = 0.5, + b0 = 2, f0 = 0) { require(MASS) if(!is.null(data$ok)) data <- subset(data,ok!="no fit") # Don't use data @@ -114,7 +115,7 @@ drfit <- function(data, startlogED50 = NA, chooseone=TRUE, length(subset(allWrong,allWrong == i))==0) { m <- try(nls(response ~ pnorm(-log10(dose),-logED50,scale), data=tmp, - start=list(logED50=startlogED50[[i]],scale=1))) + start=list(logED50=startlogED50[[i]],scale=ps0))) if (chooseone==FALSE || fit==FALSE) { if (!inherits(m, "try-error")) { fit <- TRUE @@ -157,7 +158,7 @@ drfit <- function(data, startlogED50 = NA, chooseone=TRUE, length(subset(allWrong,allWrong == i))==0) { m <- try(nls(response ~ plogis(-log10(dose),-logED50,scale), data=tmp, - start=list(logED50=startlogED50[[i]],scale=1))) + start=list(logED50=startlogED50[[i]],scale=ls0))) if (chooseone==FALSE || fit==FALSE) { if (!inherits(m, "try-error")) { fit <- TRUE @@ -199,7 +200,7 @@ drfit <- function(data, startlogED50 = NA, chooseone=TRUE, length(subset(allWrong,allWrong == i))==0) { m <- try(nls(response ~ pweibull(-log10(dose)+location,shape), data=tmp, - start=list(location=startlogED50[[i]],shape=s0))) + start=list(location=startlogED50[[i]],shape=ws0))) if (chooseone==FALSE || fit==FALSE) { if (!inherits(m, "try-error")) { fit <- TRUE @@ -273,10 +274,10 @@ drfit <- function(data, startlogED50 = NA, chooseone=TRUE, } results <- data.frame(rsubstance, rndl, rn, rlld, rlhd, mtype, logED50, logED50low, logED50high, runit, sigma, a, b) - names(results) <- c("Substance","ndl","n","lld","lhd","mtype","logED50", - paste(100*(1-level)/2,"%",sep=""), - paste(100*(1+level)/2,"%",sep=""), - "unit","sigma","a","b") + names(results) <- c("Substance","ndl","n","lld","lhd","mtype","logED50", + paste(100*(1-level)/2,"%",sep=""), + paste(100*(1+level)/2,"%",sep=""), + "unit","sigma","a","b") if (linlogit) { results$c <- c |