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<html><head><title>Get dose-response data</title>
<link rel="stylesheet" type="text/css" href="Rchm.css">
</head>
<body>
<table width="100%"><tr><td>drdata(drfit)</td><td align="right">R Documentation</td></tr></table><object type="application/x-oleobject" classid="clsid:1e2a7bd0-dab9-11d0-b93a-00c04fc99f9e">
<param name="keyword" value="R: drdata">
<param name="keyword" value=" Get dose-response data">
</object>
<h2>Get dose-response data</h2>
<h3>Description</h3>
<p>
Get dose-response data from a remote mysql server
</p>
<h3>Usage</h3>
<pre>
drdata(substances, experimentator = "%", db = "cytotox", celltype = "IPC-81",
whereClause = "1", ok = "'ok'")
</pre>
<h3>Arguments</h3>
<table summary="R argblock">
<tr valign="top"><td><code>substances</code></td>
<td>
A string or an array of strings with the substance names for
which dose-response data is to be retrieved.</td></tr>
<tr valign="top"><td><code>experimentator</code></td>
<td>
The name of the experimentator whose data is to be used.</td></tr>
<tr valign="top"><td><code>db</code></td>
<td>
The database to be used. Currently only "cytotox" of the UFT Department of
Bioorganic Chemistry is supported.</td></tr>
<tr valign="top"><td><code>celltype</code></td>
<td>
Currently, only data for IPC-81, C6, NB4, HeLa, Jurkat and U937 are supported.</td></tr>
<tr valign="top"><td><code>whereClause</code></td>
<td>
With this argument, additional conditions for the SQL query can be set,
e.g. "where plate != 710". The default is 1 (in SQL syntax this means TRUE).</td></tr>
<tr valign="top"><td><code>ok</code></td>
<td>
With the default value "'ok'", only data that has been checked and set to "ok"
in the database is retrieved. Another sensible argument would be "'ok','?'", in
order to additionally retrieve data which has not yet been checked.</td></tr>
</table>
<h3>Details</h3>
<p>
The function is currently only used for retrieving data from the
mysql database "cytotox" of the UFT Department of Bioorganic Chemistry.
Access to this database is limited to UFT staff. Additionally to the
installation of the RODBC package, it is required to set up a ODBC data
source with the name "cytotox", using an ODBC driver for mysql, probably
myODBC. Then, under Unix, you can use iodbc or unixodbc for setting up the
respective data source with data source name (DSN) "cytotox". For my
setting using unixodbc, I am using the file ‘<TT>/etc/odbcinst.ini</TT>’
containing:
<table summary="Rd table">
<tr>
<td align="left">[MySQL] </td> <td align="left"> </td> <td align="left"> </td>
</tr>
<tr>
<td align="left"> Description </td> <td align="left"> = </td> <td align="left"> MySQL driver for ODBC </td>
</tr>
<tr>
<td align="left"> Driver </td> <td align="left"> = </td> <td align="left"> /usr/local/lib/libmyodbc.so </td>
</tr>
<tr>
<td align="left"> Setup </td> <td align="left"> = </td> <td align="left"> /usr/lib/odbc/libodbcmyS.so </td>
</tr>
</table>
<p>
and the file ‘<TT>/etc/odbc.ini</TT>’ containing:
<table summary="Rd table">
<tr>
<td align="left">[cytotox] </td> <td align="left"> </td> <td align="left"> </td>
</tr>
<tr>
<td align="left"> Description </td> <td align="left"> = </td> <td align="left"> Cytotoxicity database of the department of bioorganic chemistry, UFT Bremen </td>
</tr>
<tr>
<td align="left"> Driver </td> <td align="left"> = </td> <td align="left"> MySQL </td>
</tr>
<tr>
<td align="left"> Trace </td> <td align="left"> = </td> <td align="left"> Yes </td>
</tr>
<tr>
<td align="left"> TraceFile </td> <td align="left"> = </td> <td align="left"> /tmp/odbc.log </td>
</tr>
<tr>
<td align="left"> Database </td> <td align="left"> = </td> <td align="left"> cytotox </td>
</tr>
<tr>
<td align="left"> Server </td> <td align="left"> = </td> <td align="left"> eckehaat </td>
</tr>
<tr>
<td align="left"> Port </td> <td align="left"> = </td> <td align="left"> 3306 </td>
</tr>
</table>
.
</p>
<h3>Value</h3>
<table summary="R argblock">
<tr valign="top"><td><code>data</code></td>
<td>
A data frame with a factor describing the dose levels, the numeric dose levels
and a numeric column describing the response, as well as the entries for
plate, experimentator, performed (date of test performance), celltype, unit
(of the dose/concentration), and for the ok field in the database.</td></tr>
</table>
<h3>Author(s)</h3>
<p>
Johannes Ranke
<a href="mailto:jranke@uni-bremen.de">jranke@uni-bremen.de</a>
<a href="http://www.uft.uni-bremen.de/chemie/ranke">http://www.uft.uni-bremen.de/chemie/ranke</a>
</p>
<h3>Examples</h3>
<pre>
# Get cytotoxicity data for Tributyltin and zinc pyrithione, tested with IPC-81 cells
## Not run: data <- drdata(c("TBT","Zn Pyrithion"))
</pre>
<hr><div align="center"><a href="00Index.html">[Package Contents]</a></div>
</body></html>
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