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<title>Dose-Response data for 1-methyl-3-alkylimidazolium tetrafluoroborates in IPC-81 cells — IM1xIPC81 • drfit</title>

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    <h1>Dose-Response data for 1-methyl-3-alkylimidazolium tetrafluoroborates in IPC-81 cells</h1>
    </div>

    
    <p>This is the raw data documenting the influence of the alkyl
  chain length in 3 position on the toxicity to the
  promyelocytic leukemia rat cell line IPC-81. The substances
  are named according to the UFT naming scheme of these
  substances. IM13 BF4 means 1-methyl-3-propylimidazolium
  tetrafluoroborate, IM14 BF4 means
  1-methyl-3-butylimidazolium tetrafluoroborate and IM1-10
  BF4 means 1-methyl-3-decylimidazolium tetrafluoroborate.
  This is a subset (only the BF4 anion) of the data
  shown in Figure 3 in Ranke et al. (2004).</p>
    

    <pre><span class='fu'>data</span>(<span class='no'>IM1xIPC81</span>)</pre>
        
    <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2>

    <p>A dataframe containing the data as required for the
  <code><a href='drfit.html'>drfit</a></code> function. An additional column contains
  the tested organism (name of the cell line).</p>
    
    <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2>

    <p>Ranke J, Mölter K, Stock F, Bottin-Weber U, Poczobutt J,
  Hoffmann J, Ondruschka B, Filser J, Jastorff B (2004)
  Biological effects of imidazolium ionic liquids with varying
  chain lenghts in acute Vibrio fischeri and WST-1 cell
  viability assays. Ecotoxicology and Environmental Safety
  58(3) 396-404</p>
    

    <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2>
    <pre class="examples"><div class='input'>  <span class='no'>rIM1xIPC81</span> <span class='kw'>&lt;-</span> <span class='fu'><a href='drfit.html'>drfit</a></span>(<span class='no'>IM1xIPC81</span>, <span class='kw'>linlogit</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>showED50</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>EDx</span> <span class='kw'>=</span> <span class='fl'>10</span>)</div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM13 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM14 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='warning'>Warning: NaNs wurden erzeugt</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM15 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM16 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM17 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#&gt; <span class='warning'>Warning: NaNs wurden erzeugt</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM18 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#&gt; <span class='warning'>Warning: NaNs wurden erzeugt</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM19 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#&gt; <span class='warning'>Warning: NaNs wurden erzeugt</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM1-10 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'>Waiting for profiling to be done...</span></div><div class='input'>
  <span class='no'>rIM1xIPC81.drc</span> <span class='kw'>&lt;-</span> <span class='fu'><a href='drcfit.html'>drcfit</a></span>(<span class='no'>IM1xIPC81</span>, <span class='kw'>linlogit</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>showED50</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>EDx</span> <span class='kw'>=</span> <span class='fl'>10</span>)</div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM13 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM14 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM15 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM16 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM17 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM18 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM19 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM1-10 BF4: Fitting data...</span></div><div class='input'>
  <span class='fu'>print</span>(<span class='no'>rIM1xIPC81</span>,<span class='kw'>digits</span><span class='kw'>=</span><span class='fl'>4</span>)</div><div class='output co'>#&gt;    Substance ndl   n     lld   lhd    mtype logED50  2.5%  97.5%   unit  sigma
#&gt; 1   IM13 BF4   9  81  0.5918 3.000 inactive      NA    NA     NA microM     NA
#&gt; 2   IM14 BF4  20 216 -0.0103 3.176   no fit      NA    NA     NA microM     NA
#&gt; 3   IM15 BF4   9 135  0.5918 3.000 inactive      NA    NA     NA microM     NA
#&gt; 4   IM16 BF4   9 108  0.5918 3.000 inactive      NA    NA     NA microM     NA
#&gt; 5   IM17 BF4   9  81  0.5918 3.000 linlogit  2.5786 2.506 2.6617 microM 0.2376
#&gt; 6   IM18 BF4   9 135  0.5918 3.000 linlogit  1.6806 1.623 1.7419 microM 0.2325
#&gt; 7   IM19 BF4   9  81  0.5918 3.000 linlogit  1.6496 1.598 1.7031 microM 0.1453
#&gt; 8 IM1-10 BF4  11 162 -0.0103 3.000 linlogit  0.7697 0.687 0.8544 microM 0.2988
#&gt;        a     b       c    ED50 ED50 2.5% ED50 97.5%   EDx10
#&gt; 1     NA    NA      NA      NA        NA         NA      NA
#&gt; 2     NA    NA      NA      NA        NA         NA      NA
#&gt; 3     NA    NA      NA      NA        NA         NA      NA
#&gt; 4     NA    NA      NA      NA        NA         NA      NA
#&gt; 5 2.5786 2.300 0.01468 378.941   320.424    458.918 230.782
#&gt; 6 1.6806 2.237 0.05719  47.930    41.973     55.194  27.367
#&gt; 7 1.6496 1.977 0.10956  44.628    39.671     50.483  23.031
#&gt; 8 0.7697 1.936 0.45809   5.884     4.864      7.152   2.835</div><div class='input'>  <span class='fu'>print</span>(<span class='no'>rIM1xIPC81.drc</span>,<span class='kw'>digits</span><span class='kw'>=</span><span class='fl'>4</span>)</div><div class='output co'>#&gt;    Substance ndl   n     lld   lhd    mtype logED50   2.5%  97.5%   unit  sigma
#&gt; 1   IM13 BF4   9  81  0.5918 3.000 inactive      NA     NA     NA microM     NA
#&gt; 2   IM14 BF4  20 216 -0.0103 3.176 linlogit      NA     NA     NA microM 0.1529
#&gt; 3   IM15 BF4   9 135  0.5918 3.000 inactive      NA     NA     NA microM     NA
#&gt; 4   IM16 BF4   9 108  0.5918 3.000 inactive      NA     NA     NA microM     NA
#&gt; 5   IM17 BF4   9  81  0.5918 3.000 linlogit  2.5786 2.4935 2.6497 microM 0.2376
#&gt; 6   IM18 BF4   9 135  0.5918 3.000 linlogit  1.6806 1.6168 1.7362 microM 0.2325
#&gt; 7   IM19 BF4   9  81  0.5918 3.000 linlogit  1.6496 1.5940 1.6990 microM 0.1453
#&gt; 8 IM1-10 BF4  11 162 -0.0103 3.000 linlogit  0.7697 0.6774 0.8458 microM 0.2988
#&gt;           a      b          c    ED50 ED50 2.5% ED50 97.5%   EDx10 EDx10 2.5%
#&gt; 1        NA     NA         NA      NA        NA         NA      NA         NA
#&gt; 2 5.390e+15 0.3148 -0.0001736      NA        NA         NA      NA         NA
#&gt; 3        NA     NA         NA      NA        NA         NA      NA         NA
#&gt; 4        NA     NA         NA      NA        NA         NA      NA         NA
#&gt; 5 1.281e+02 2.3001  0.0146821 378.964   311.555    446.372 230.790    202.915
#&gt; 6 2.079e+01 2.2373  0.0571925  47.930    41.382     54.478  27.367     23.809
#&gt; 7 1.342e+01 1.9773  0.1094542  44.630    39.260     50.000  23.036     20.614
#&gt; 8 2.258e+00 1.9362  0.4580784   5.884     4.758      7.011   2.835      2.181
#&gt;   EDx10 97.5%
#&gt; 1          NA
#&gt; 2          NA
#&gt; 3          NA
#&gt; 4          NA
#&gt; 5     258.665
#&gt; 6      30.925
#&gt; 7      25.459
#&gt; 8       3.489</div></pre>
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