1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
|
<!-- Generated by pkgdown: do not edit by hand -->
<!DOCTYPE html>
<html>
<head>
<meta charset="utf-8">
<meta http-equiv="X-UA-Compatible" content="IE=edge">
<meta name="viewport" content="width=device-width, initial-scale=1.0">
<title>Dose-Response data for 1-methyl-3-alkylimidazolium tetrafluoroborates in V. fischeri — IM1xVibrio • drfit</title>
<!-- jquery -->
<script src="https://code.jquery.com/jquery-3.1.0.min.js" integrity="sha384-nrOSfDHtoPMzJHjVTdCopGqIqeYETSXhZDFyniQ8ZHcVy08QesyHcnOUpMpqnmWq" crossorigin="anonymous"></script>
<!-- Bootstrap -->
<link href="https://maxcdn.bootstrapcdn.com/bootstrap/3.3.7/css/bootstrap.min.css" rel="stylesheet" integrity="sha384-BVYiiSIFeK1dGmJRAkycuHAHRg32OmUcww7on3RYdg4Va+PmSTsz/K68vbdEjh4u" crossorigin="anonymous">
<script src="https://maxcdn.bootstrapcdn.com/bootstrap/3.3.7/js/bootstrap.min.js" integrity="sha384-Tc5IQib027qvyjSMfHjOMaLkfuWVxZxUPnCJA7l2mCWNIpG9mGCD8wGNIcPD7Txa" crossorigin="anonymous"></script>
<!-- Font Awesome icons -->
<link href="https://maxcdn.bootstrapcdn.com/font-awesome/4.6.3/css/font-awesome.min.css" rel="stylesheet" integrity="sha384-T8Gy5hrqNKT+hzMclPo118YTQO6cYprQmhrYwIiQ/3axmI1hQomh7Ud2hPOy8SP1" crossorigin="anonymous">
<!-- pkgdown -->
<link href="../pkgdown.css" rel="stylesheet">
<script src="../jquery.sticky-kit.min.js"></script>
<script src="../pkgdown.js"></script>
<!-- mathjax -->
<script src='https://cdn.mathjax.org/mathjax/latest/MathJax.js?config=TeX-AMS-MML_HTMLorMML'></script>
<!--[if lt IE 9]>
<script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script>
<script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script>
<![endif]-->
</head>
<body>
<div class="container template-reference-topic">
<header>
<div class="navbar navbar-default navbar-fixed-top" role="navigation">
<div class="container">
<div class="navbar-header">
<button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar">
<span class="icon-bar"></span>
<span class="icon-bar"></span>
<span class="icon-bar"></span>
</button>
<a class="navbar-brand" href="../index.html">drfit</a>
</div>
<div id="navbar" class="navbar-collapse collapse">
<ul class="nav navbar-nav">
<li>
<a href="../reference/index.html">Reference</a>
</li>
</ul>
<ul class="nav navbar-nav navbar-right">
</ul>
</div><!--/.nav-collapse -->
</div><!--/.container -->
</div><!--/.navbar -->
</header>
<div class="row">
<div class="col-md-9 contents">
<div class="page-header">
<h1>Dose-Response data for 1-methyl-3-alkylimidazolium tetrafluoroborates in V. fischeri</h1>
</div>
<p>This is the raw data documenting the influence of the alkyl chain length in 3
position on the toxicity to the marine luminescent bacteria <em>V.
fischeri</em>. The substances are named according to the UFT naming scheme of
these substances.
IM13 BF4 means 1-methyl-3-propylimidazolium tetrafluoroborate,
IM14 BF4 means 1-methyl-3-butylimidazolium tetrafluoroborate and
IM1-10 BF4 means 1-methyl-3-decylimidazolium tetrafluoroborate.</p>
<pre><span class='fu'>data</span>(<span class='no'>IM1xVibrio</span>)</pre>
<h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2>
<p>A dataframe containing the data as required for the <code><a href='drfit.html'>drfit</a></code>
function. Additional columns contain the species tested (luminescent bacteria
Vibrio fischeri, <code>organism</code>), and a field specifying if the data is
regarded valid (<code>ok</code>).</p>
<h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2>
<p>Ranke J, Mölter K, Stock F, Bottin-Weber U, Poczobutt J, Hoffmann J,
Ondruschka B, Filser J, Jastorff B (2004) Biological effects of imidazolium
ionic liquids with varying chain lenghts in acute Vibrio fischeri and WST-1
cell viability assays. Ecotoxicology and Environmental Safety 58(3) 396-404</p>
<h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2>
<pre class="examples"><div class='input'> <span class='no'>rIM1xVibrio</span> <span class='kw'><-</span> <span class='fu'><a href='drfit.html'>drfit</a></span>(<span class='no'>IM1xVibrio</span>, <span class='kw'>logit</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>chooseone</span> <span class='kw'>=</span> <span class='fl'>FALSE</span>,
<span class='kw'>showED50</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>EDx</span> <span class='kw'>=</span> <span class='fu'>c</span>(<span class='fl'>10</span>, <span class='fl'>20</span>))</div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM13 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM14 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM15 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM16 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM17 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM18 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM19 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM1-10 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='input'> <span class='fu'>print</span>(<span class='no'>rIM1xVibrio</span>, <span class='kw'>digits</span> <span class='kw'>=</span> <span class='fl'>4</span>)</div><div class='output co'>#> Substance ndl n lld lhd mtype logED50 2.5% 97.5% unit sigma
#> 1 IM13 BF4 13 22 -5.301 4.699 probit 3.9399 3.8636 4.0160 microM 0.06303
#> 2 IM13 BF4 13 22 -5.301 4.699 logit 3.9461 3.8708 4.0211 microM 0.06188
#> 3 IM14 BF4 12 57 -4.301 4.699 probit 3.5442 3.5030 3.5855 microM 0.05905
#> 4 IM14 BF4 12 57 -4.301 4.699 logit 3.5465 3.5044 3.5885 microM 0.06030
#> 5 IM15 BF4 7 20 -0.301 4.699 probit 3.1398 3.1136 3.1662 microM 0.02695
#> 6 IM15 BF4 7 20 -0.301 4.699 logit 3.1387 3.1118 3.1659 microM 0.02723
#> 7 IM16 BF4 13 30 -4.301 4.699 probit 3.1804 3.1436 3.2176 microM 0.04514
#> 8 IM16 BF4 13 30 -4.301 4.699 logit 3.1814 3.1440 3.2190 microM 0.04553
#> 9 IM17 BF4 10 20 -1.301 4.699 probit 2.4317 2.3681 2.4951 microM 0.04773
#> 10 IM17 BF4 10 20 -1.301 4.699 logit 2.4353 2.3672 2.5026 microM 0.05050
#> 11 IM18 BF4 10 17 -2.301 2.699 probit 1.4015 1.3147 1.4881 microM 0.05611
#> 12 IM18 BF4 10 17 -2.301 2.699 logit 1.4051 1.3129 1.4966 microM 0.05898
#> 13 IM19 BF4 13 22 -5.301 2.699 probit 0.7158 0.6704 0.7592 microM 0.02956
#> 14 IM19 BF4 13 22 -5.301 2.699 logit 0.7172 0.6689 0.7635 microM 0.03210
#> 15 IM1-10 BF4 11 20 -6.301 2.699 probit -0.1790 -0.2569 -0.1037 microM 0.04099
#> 16 IM1-10 BF4 11 20 -6.301 2.699 logit -0.1831 -0.2620 -0.1055 microM 0.04192
#> a b ED50 ED50 2.5% ED50 97.5% EDx10 EDx20
#> 1 3.9399 0.5763 8707.8956 7305.0279 1.038e+04 1.590e+03 2850.222
#> 2 3.9461 0.3426 8832.9407 7426.2282 1.050e+04 1.561e+03 2959.147
#> 3 3.5442 0.6561 3501.1558 3184.3196 3.851e+03 5.051e+02 981.759
#> 4 3.5465 0.3911 3519.5779 3194.6808 3.877e+03 4.867e+02 1010.014
#> 5 3.1398 0.5527 1379.9037 1298.9533 1.466e+03 2.701e+02 472.823
#> 6 3.1387 0.3347 1376.4086 1293.7152 1.465e+03 2.532e+02 472.911
#> 7 3.1804 0.4882 1515.0421 1391.8150 1.650e+03 3.588e+02 588.292
#> 8 3.1814 0.2957 1518.4650 1393.2665 1.656e+03 3.401e+02 590.840
#> 9 2.4317 0.6387 270.2279 233.3814 3.127e+02 4.105e+01 78.382
#> 10 2.4353 0.3810 272.4409 232.9287 3.182e+02 3.965e+01 80.754
#> 11 1.4015 0.8009 25.2069 20.6383 3.077e+01 2.372e+00 5.340
#> 12 1.4051 0.4816 25.4135 20.5545 3.138e+01 2.222e+00 5.463
#> 13 0.7158 0.6969 5.1975 4.6814 5.744e+00 6.647e-01 1.347
#> 14 0.7172 0.4132 5.2141 4.6652 5.801e+00 6.446e-01 1.394
#> 15 -0.1790 0.8019 0.6622 0.5534 7.876e-01 6.212e-02 0.140
#> 16 -0.1831 0.4816 0.6560 0.5470 7.843e-01 5.738e-02 0.141</div><div class='input'>
<span class='no'>rIM1xVibrio.drc</span> <span class='kw'><-</span> <span class='fu'><a href='drcfit.html'>drcfit</a></span>(<span class='no'>IM1xVibrio</span>, <span class='kw'>logit</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>chooseone</span> <span class='kw'>=</span> <span class='fl'>FALSE</span>,
<span class='kw'>showED50</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>EDx</span> <span class='kw'>=</span> <span class='fu'>c</span>(<span class='fl'>10</span>, <span class='fl'>20</span>))</div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM13 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM14 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM15 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM16 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM17 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM18 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM19 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM1-10 BF4: Fitting data...</span></div><div class='input'> <span class='fu'>print</span>(<span class='no'>rIM1xVibrio.drc</span>, <span class='kw'>digits</span> <span class='kw'>=</span> <span class='fl'>4</span>)</div><div class='output co'>#> Substance ndl n lld lhd mtype logED50 2.5% 97.5% unit sigma
#> 1 IM13 BF4 13 22 -5.301 4.699 probit 3.9399 3.8563 4.0100 microM 0.06303
#> 2 IM13 BF4 13 22 -5.301 4.699 logit 3.9461 3.8637 4.0153 microM 0.06188
#> 3 IM14 BF4 12 57 -4.301 4.699 probit 3.5442 3.5009 3.5836 microM 0.05905
#> 4 IM14 BF4 12 57 -4.301 4.699 logit 3.5465 3.5023 3.5866 microM 0.06030
#> 5 IM15 BF4 7 20 -0.301 4.699 probit 3.1398 3.1127 3.1654 microM 0.02695
#> 6 IM15 BF4 7 20 -0.301 4.699 logit 3.1387 3.1109 3.1649 microM 0.02723
#> 7 IM16 BF4 13 30 -4.301 4.699 probit 3.1804 3.1419 3.2158 microM 0.04514
#> 8 IM16 BF4 13 30 -4.301 4.699 logit 3.1814 3.1424 3.2172 microM 0.04553
#> 9 IM17 BF4 10 20 -1.301 4.699 probit 2.4317 2.3632 2.4909 microM 0.04773
#> 10 IM17 BF4 10 20 -1.301 4.699 logit 2.4353 2.3618 2.4981 microM 0.05050
#> 11 IM18 BF4 10 17 -2.301 2.699 probit 1.4015 1.3052 1.4803 microM 0.05611
#> 12 IM18 BF4 10 17 -2.301 2.699 logit 1.4051 1.3023 1.4881 microM 0.05898
#> 13 IM19 BF4 13 22 -5.301 2.699 probit 0.7158 0.6690 0.7580 microM 0.02956
#> 14 IM19 BF4 13 22 -5.301 2.699 logit 0.7172 0.6672 0.7620 microM 0.03210
#> 15 IM1-10 BF4 11 20 -6.301 2.699 probit -0.1790 -0.2628 -0.1088 microM 0.04099
#> 16 IM1-10 BF4 11 20 -6.301 2.699 logit -0.1831 -0.2690 -0.1114 microM 0.04192
#> a b ED50 ED50 2.5% ED50 97.5% EDx10 EDx10 2.5%
#> 1 8707.5571 -0.7536 8707.5571 7183.0127 1.023e+04 1.590e+03 968.72501
#> 2 8832.8773 1.2676 8832.8773 7306.8669 1.036e+04 1.561e+03 925.39582
#> 3 3501.1967 -0.6619 3501.1967 3168.9639 3.833e+03 5.051e+02 395.26341
#> 4 3519.5773 1.1105 3519.5773 3179.2923 3.860e+03 4.866e+02 371.84710
#> 5 1379.9019 -0.7858 1379.9019 1296.3162 1.463e+03 2.701e+02 233.25320
#> 6 1376.4086 1.2976 1376.4086 1290.8397 1.462e+03 2.531e+02 215.79719
#> 7 1515.0427 -0.8896 1515.0427 1386.3308 1.644e+03 3.588e+02 283.79434
#> 8 1518.4644 1.4686 1518.4644 1387.9173 1.649e+03 3.401e+02 262.20564
#> 9 270.2279 -0.6800 270.2279 230.7905 3.097e+02 4.105e+01 27.78507
#> 10 272.4526 1.1401 272.4526 230.0588 3.148e+02 3.966e+01 25.34948
#> 11 25.2059 -0.5423 25.2059 20.1927 3.022e+01 2.372e+00 1.29116
#> 12 25.4145 0.9017 25.4145 20.0576 3.077e+01 2.223e+00 1.09707
#> 13 5.1971 -0.6231 5.1971 4.6665 5.728e+00 6.646e-01 0.49235
#> 14 5.2141 1.0511 5.2141 4.6477 5.781e+00 6.446e-01 0.46046
#> 15 0.6622 -0.5416 0.6622 0.5460 7.783e-01 6.213e-02 0.03513
#> 16 0.6560 0.9018 0.6560 0.5383 7.737e-01 5.738e-02 0.03163
#> EDx10 97.5% EDx20 EDx20 2.5% EDx20 97.5%
#> 1 2.211e+03 2850.328 2.019e+03 3681.2703
#> 2 2.196e+03 2958.988 2.092e+03 3826.1457
#> 3 6.149e+02 981.743 8.254e+02 1138.0862
#> 4 6.014e+02 1010.061 8.414e+02 1178.7611
#> 5 3.070e+02 472.838 4.257e+02 520.0197
#> 6 2.905e+02 472.906 4.239e+02 521.8955
#> 7 4.337e+02 588.259 4.999e+02 676.6627
#> 8 4.181e+02 590.824 4.972e+02 684.4677
#> 9 5.431e+01 78.383 5.955e+01 97.2142
#> 10 5.396e+01 80.763 5.975e+01 101.7713
#> 11 3.454e+00 5.339 3.544e+00 7.1350
#> 12 3.348e+00 5.463 3.489e+00 7.4370
#> 13 8.369e-01 1.346 1.084e+00 1.6086
#> 14 8.288e-01 1.394 1.106e+00 1.6832
#> 15 8.912e-02 0.140 9.501e-02 0.1850
#> 16 8.314e-02 0.141 9.588e-02 0.1862</div></pre>
</div>
<div class="col-md-3 hidden-xs hidden-sm" id="sidebar">
<h2>Contents</h2>
<ul class="nav nav-pills nav-stacked">
<li><a href="#format">Format</a></li>
<li><a href="#source">Source</a></li>
<li><a href="#examples">Examples</a></li>
</ul>
</div>
</div>
<footer>
<div class="copyright">
<p>Developed by Johannes Ranke.</p>
</div>
<div class="pkgdown">
<p>Site built with <a href="http://hadley.github.io/pkgdown/">pkgdown</a>.</p>
</div>
</footer>
</div>
</body>
</html>
|
