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<!DOCTYPE html>
<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1.0"><title>Dose-Response data for TBT and Zink Pyrithione in IPC-81 cells — antifoul • drfit</title><!-- jquery --><script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.4.1/jquery.min.js" integrity="sha256-CSXorXvZcTkaix6Yvo6HppcZGetbYMGWSFlBw8HfCJo=" crossorigin="anonymous"></script><!-- Bootstrap --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/css/bootstrap.min.css" integrity="sha256-bZLfwXAP04zRMK2BjiO8iu9pf4FbLqX6zitd+tIvLhE=" crossorigin="anonymous"><script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.4.1/js/bootstrap.min.js" integrity="sha256-nuL8/2cJ5NDSSwnKD8VqreErSWHtnEP9E7AySL+1ev4=" crossorigin="anonymous"></script><!-- bootstrap-toc --><link rel="stylesheet" href="../bootstrap-toc.css"><script src="../bootstrap-toc.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- pkgdown --><link href="../pkgdown.css" rel="stylesheet"><script src="../pkgdown.js"></script><meta property="og:title" content="Dose-Response data for TBT and Zink Pyrithione in IPC-81 cells — antifoul"><meta property="og:description" content='This data set shows the response of the rat leukaemic cell line IPC-81 to
dilution series of tributyltin chloride (TBT) and Zink Pyrithione as retrieved
from the "cytotox" database of the UFT Department of Bioorganic Chemistry on
February 25, 2004'><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
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<h1>Dose-Response data for TBT and Zink Pyrithione in IPC-81 cells</h1>
<div class="hidden name"><code>antifoul.Rd</code></div>
</div>
<div class="ref-description">
<p>This data set shows the response of the rat leukaemic cell line IPC-81 to
dilution series of tributyltin chloride (TBT) and Zink Pyrithione as retrieved
from the "cytotox" database of the UFT Department of Bioorganic Chemistry on
February 25, 2004</p>
</div>
<div id="ref-usage">
<div class="sourceCode"><pre class="sourceCode r"><code><span><span class="fu"><a href="https://rdrr.io/r/utils/data.html" class="external-link">data</a></span><span class="op">(</span><span class="va">antifoul</span><span class="op">)</span></span></code></pre></div>
</div>
<div id="format">
<h2>Format</h2>
<p>A dataframe containing 135 and 81 data points for concentrations and responses
for TBT and Zink Pyrithione, respectively. Some additional columns from the
database are also present.</p>
</div>
<div id="ref-examples">
<h2>Examples</h2>
<div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span><span class="va">rantifoul.ED50</span> <span class="op"><-</span> <span class="fu"><a href="drfit.html">drfit</a></span><span class="op">(</span><span class="va">antifoul</span>,</span></span>
<span class="r-in"><span> linlogit <span class="op">=</span> <span class="cn">TRUE</span>, logit <span class="op">=</span> <span class="cn">TRUE</span>, weibull <span class="op">=</span> <span class="cn">TRUE</span>,</span></span>
<span class="r-in"><span> chooseone <span class="op">=</span> <span class="cn">FALSE</span>,</span></span>
<span class="r-in"><span> showED50 <span class="op">=</span> <span class="cn">TRUE</span>, EDx <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">10</span><span class="op">)</span><span class="op">)</span></span></span>
<span class="r-msg co"><span class="r-pr">#></span> </span>
<span class="r-msg co"><span class="r-pr">#></span> TBT: Fitting data...</span>
<span class="r-msg co"><span class="r-pr">#></span> Waiting for profiling to be done...</span>
<span class="r-msg co"><span class="r-pr">#></span> Waiting for profiling to be done...</span>
<span class="r-msg co"><span class="r-pr">#></span> Waiting for profiling to be done...</span>
<span class="r-msg co"><span class="r-pr">#></span> </span>
<span class="r-msg co"><span class="r-pr">#></span> Zn Pyrithion: Fitting data...</span>
<span class="r-msg co"><span class="r-pr">#></span> Waiting for profiling to be done...</span>
<span class="r-msg co"><span class="r-pr">#></span> Waiting for profiling to be done...</span>
<span class="r-msg co"><span class="r-pr">#></span> Waiting for profiling to be done...</span>
<span class="r-in"><span><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">rantifoul.ED50</span>, digits <span class="op">=</span> <span class="fl">5</span><span class="op">)</span></span></span>
<span class="r-out co"><span class="r-pr">#></span> Substance ndl n lld lhd mtype logED50 2.5% 97.5%</span>
<span class="r-out co"><span class="r-pr">#></span> 1 TBT 38 135 -2.7093 2.3979 linlogit -0.15810 -0.26021 -0.050475</span>
<span class="r-out co"><span class="r-pr">#></span> 2 TBT 38 135 -2.7093 2.3979 probit -0.16436 -0.26504 -0.056498</span>
<span class="r-out co"><span class="r-pr">#></span> 3 TBT 38 135 -2.7093 2.3979 logit -0.16012 -0.26116 -0.052591</span>
<span class="r-out co"><span class="r-pr">#></span> 4 TBT 38 135 -2.7093 2.3979 weibull -0.11507 NA NA</span>
<span class="r-out co"><span class="r-pr">#></span> 5 Zn Pyrithion 27 81 -2.1072 2.0000 linlogit -0.41329 -0.52932 -0.299799</span>
<span class="r-out co"><span class="r-pr">#></span> 6 Zn Pyrithion 27 81 -2.1072 2.0000 probit -0.39792 -0.50783 -0.291563</span>
<span class="r-out co"><span class="r-pr">#></span> 7 Zn Pyrithion 27 81 -2.1072 2.0000 logit -0.40035 -0.51049 -0.293501</span>
<span class="r-out co"><span class="r-pr">#></span> 8 Zn Pyrithion 27 81 -2.1072 2.0000 weibull -0.38795 NA NA</span>
<span class="r-out co"><span class="r-pr">#></span> unit sigma a b c ED50 ED50 2.5% ED50 97.5%</span>
<span class="r-out co"><span class="r-pr">#></span> 1 microM 0.19264 -0.15810 1.04066 -0.024161 0.69487 0.54927 0.89028</span>
<span class="r-out co"><span class="r-pr">#></span> 2 microM 0.19286 -0.16436 0.67637 NA 0.68493 0.54320 0.87801</span>
<span class="r-out co"><span class="r-pr">#></span> 3 microM 0.19199 -0.16012 0.41358 NA 0.69164 0.54808 0.88595</span>
<span class="r-out co"><span class="r-pr">#></span> 4 microM 0.18810 0.63743 1.28891 NA 0.76724 NA NA</span>
<span class="r-out co"><span class="r-pr">#></span> 5 microM 0.22878 -0.41329 1.74249 0.610809 0.38611 0.29558 0.50142</span>
<span class="r-out co"><span class="r-pr">#></span> 6 microM 0.22866 -0.39792 0.41696 NA 0.40002 0.31058 0.51102</span>
<span class="r-out co"><span class="r-pr">#></span> 7 microM 0.22802 -0.40035 0.25395 NA 0.39779 0.30868 0.50874</span>
<span class="r-out co"><span class="r-pr">#></span> 8 microM 0.23008 0.47647 2.51561 NA 0.40931 NA NA</span>
<span class="r-out co"><span class="r-pr">#></span> EDx10</span>
<span class="r-out co"><span class="r-pr">#></span> 1 0.085214</span>
<span class="r-out co"><span class="r-pr">#></span> 2 0.093077</span>
<span class="r-out co"><span class="r-pr">#></span> 3 0.085340</span>
<span class="r-out co"><span class="r-pr">#></span> 4 0.053392</span>
<span class="r-out co"><span class="r-pr">#></span> 5 0.120232</span>
<span class="r-out co"><span class="r-pr">#></span> 6 0.116872</span>
<span class="r-out co"><span class="r-pr">#></span> 7 0.110068</span>
<span class="r-out co"><span class="r-pr">#></span> 8 0.121166</span>
<span class="r-in"><span></span></span>
<span class="r-in"><span><span class="va">rantifoul.drc</span> <span class="op"><-</span> <span class="fu"><a href="drcfit.html">drcfit</a></span><span class="op">(</span><span class="va">antifoul</span>,</span></span>
<span class="r-in"><span> linlogit <span class="op">=</span> <span class="cn">TRUE</span>, logit <span class="op">=</span> <span class="cn">TRUE</span>, weibull <span class="op">=</span> <span class="cn">TRUE</span>,</span></span>
<span class="r-in"><span> chooseone <span class="op">=</span> <span class="cn">FALSE</span>,</span></span>
<span class="r-in"><span> showED50 <span class="op">=</span> <span class="cn">TRUE</span>, EDx <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fl">10</span><span class="op">)</span><span class="op">)</span></span></span>
<span class="r-msg co"><span class="r-pr">#></span> </span>
<span class="r-msg co"><span class="r-pr">#></span> TBT: Fitting data...</span>
<span class="r-msg co"><span class="r-pr">#></span> </span>
<span class="r-msg co"><span class="r-pr">#></span> Zn Pyrithion: Fitting data...</span>
<span class="r-in"><span><span class="fu"><a href="https://rdrr.io/r/base/print.html" class="external-link">print</a></span><span class="op">(</span><span class="va">rantifoul.drc</span>, digits <span class="op">=</span> <span class="fl">5</span><span class="op">)</span></span></span>
<span class="r-out co"><span class="r-pr">#></span> Substance ndl n lld lhd mtype logED50 2.5% 97.5%</span>
<span class="r-out co"><span class="r-pr">#></span> 1 TBT 38 135 -2.7093 2.3979 linlogit NA NA NA</span>
<span class="r-out co"><span class="r-pr">#></span> 2 TBT 38 135 -2.7093 2.3979 probit -0.16436 -0.28178 -0.072022</span>
<span class="r-out co"><span class="r-pr">#></span> 3 TBT 38 135 -2.7093 2.3979 logit -0.16012 -0.27782 -0.067603</span>
<span class="r-out co"><span class="r-pr">#></span> 4 TBT 38 135 -2.7093 2.3979 weibull -0.13012 -0.23786 -0.043860</span>
<span class="r-out co"><span class="r-pr">#></span> 5 Zn Pyrithion 27 81 -2.1072 2.0000 linlogit -0.41330 -0.54457 -0.312631</span>
<span class="r-out co"><span class="r-pr">#></span> 6 Zn Pyrithion 27 81 -2.1072 2.0000 probit -0.39792 -0.52005 -0.302705</span>
<span class="r-out co"><span class="r-pr">#></span> 7 Zn Pyrithion 27 81 -2.1072 2.0000 logit -0.40035 -0.52324 -0.304676</span>
<span class="r-out co"><span class="r-pr">#></span> 8 Zn Pyrithion 27 81 -2.1072 2.0000 weibull -0.37351 -0.49792 -0.276917</span>
<span class="r-out co"><span class="r-pr">#></span> unit sigma a b c ED50 ED50 2.5% ED50 97.5%</span>
<span class="r-out co"><span class="r-pr">#></span> 1 microM 0.19264 0.71806 1.04061 -0.024169 NA NA NA</span>
<span class="r-out co"><span class="r-pr">#></span> 2 microM 0.19286 0.68492 -0.64209 NA 0.68492 0.52267 0.84718</span>
<span class="r-out co"><span class="r-pr">#></span> 3 microM 0.19199 0.69165 1.05007 NA 0.69165 0.52744 0.85585</span>
<span class="r-out co"><span class="r-pr">#></span> 4 microM 0.18900 -0.13012 0.79816 NA 0.74111 0.57828 0.90394</span>
<span class="r-out co"><span class="r-pr">#></span> 5 microM 0.22878 0.30926 1.74257 0.611358 0.38610 0.28538 0.48682</span>
<span class="r-out co"><span class="r-pr">#></span> 6 microM 0.22866 0.40002 -1.04159 NA 0.40002 0.30196 0.49808</span>
<span class="r-out co"><span class="r-pr">#></span> 7 microM 0.22802 0.39779 1.71015 NA 0.39779 0.29975 0.49582</span>
<span class="r-out co"><span class="r-pr">#></span> 8 microM 0.23077 -0.37351 1.19152 NA 0.42315 0.31775 0.52855</span>
<span class="r-out co"><span class="r-pr">#></span> EDx10 EDx10 2.5% EDx10 97.5%</span>
<span class="r-out co"><span class="r-pr">#></span> 1 NA NA NA</span>
<span class="r-out co"><span class="r-pr">#></span> 2 0.093074 0.040308 0.14584</span>
<span class="r-out co"><span class="r-pr">#></span> 3 0.085338 0.035963 0.13471</span>
<span class="r-out co"><span class="r-pr">#></span> 4 0.069958 0.026197 0.11372</span>
<span class="r-out co"><span class="r-pr">#></span> 5 0.120238 0.043513 0.19696</span>
<span class="r-out co"><span class="r-pr">#></span> 6 0.116878 0.048151 0.18561</span>
<span class="r-out co"><span class="r-pr">#></span> 7 0.110068 0.043085 0.17705</span>
<span class="r-out co"><span class="r-pr">#></span> 8 0.087066 0.017958 0.15617</span>
</code></pre></div>
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