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R version 2.15.1 (2012-06-22) -- "Roasted Marshmallows"
Copyright (C) 2012 The R Foundation for Statistical Computing
ISBN 3-900051-07-0
Platform: x86_64-pc-linux-gnu (64-bit)

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

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Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> library(drfit)
Loading required package: MASS
Loading required package: RODBC
> data(IM1xIPC81)
> rIM1xIPC81 <- drfit(IM1xIPC81,linlogit=TRUE)

IM13 BF4: Fitting data...


IM14 BF4: Fitting data...

Error in nls(response ~ linlogitf(dose, 1, f, logED50, b), data = tmp,  : 
  Convergence failure: false convergence (8)
Error in numericDeriv(form[[3L]], names(ind), env, ifelse(internalPars <  : 
  Missing value or an infinity produced when evaluating the model
In addition: Warning message:
In pnorm(-log10(dose), -logED50, scale) : NaNs produced

IM15 BF4: Fitting data...


IM16 BF4: Fitting data...


IM17 BF4: Fitting data...

Waiting for profiling to be done...
Error in numericDeriv(form[[3L]], names(ind), env, ifelse(internalPars <  : 
  Missing value or an infinity produced when evaluating the model
In addition: Warning message:
In pnorm(-log10(dose), -logED50, scale) : NaNs produced

IM18 BF4: Fitting data...

Waiting for profiling to be done...
Error in numericDeriv(form[[3L]], names(ind), env, ifelse(internalPars <  : 
  Missing value or an infinity produced when evaluating the model
In addition: Warning message:
In pnorm(-log10(dose), -logED50, scale) : NaNs produced

IM19 BF4: Fitting data...

Waiting for profiling to be done...
Error in numericDeriv(form[[3L]], names(ind), env, ifelse(internalPars <  : 
  Missing value or an infinity produced when evaluating the model
In addition: Warning message:
In pnorm(-log10(dose), -logED50, scale) : NaNs produced

IM1-10 BF4: Fitting data...

Waiting for profiling to be done...
> print(rIM1xIPC81,digits=4)
   Substance ndl   n     lld   lhd    mtype logED50  2.5%  97.5%   unit  sigma
1   IM13 BF4   9  81  0.5918 3.000 inactive      NA    NA     NA microM     NA
2   IM14 BF4  20 216 -0.0103 3.176   no fit      NA    NA     NA microM     NA
3   IM15 BF4   9 135  0.5918 3.000 inactive      NA    NA     NA microM     NA
4   IM16 BF4   9 108  0.5918 3.000 inactive      NA    NA     NA microM     NA
5   IM17 BF4   9  81  0.5918 3.000 linlogit  2.5786 2.506 2.6617 microM 0.2376
6   IM18 BF4   9 135  0.5918 3.000 linlogit  1.6806 1.623 1.7419 microM 0.2325
7   IM19 BF4   9  81  0.5918 3.000 linlogit  1.6496 1.598 1.7031 microM 0.1453
8 IM1-10 BF4  11 162 -0.0103 3.000 linlogit  0.7697 0.687 0.8544 microM 0.2988
       a     b       c
1     NA    NA      NA
2     NA    NA      NA
3     NA    NA      NA
4     NA    NA      NA
5 2.5786 2.300 0.01468
6 1.6806 2.237 0.05719
7 1.6496 1.977 0.10956
8 0.7697 1.936 0.45809
> 
> proc.time()
   user  system elapsed 
  0.852   0.024   0.869 

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