diff options
| -rw-r--r-- | R/mkinmod.R | 11 | ||||
| -rw-r--r-- | TODO | 2 |
2 files changed, 10 insertions, 3 deletions
diff --git a/R/mkinmod.R b/R/mkinmod.R index 37f96ce..8095932 100644 --- a/R/mkinmod.R +++ b/R/mkinmod.R @@ -145,11 +145,18 @@ mkinmod <- function(...) m <- matrix(nrow=n, ncol=n, dimnames=list(boxes, boxes))
for (from in boxes) {
for (to in boxes) {
- if (from == to) {
+ if (from == to) { # diagonal elements
k.candidate = paste("k", from, sep="_")
m[from,to] = ifelse(k.candidate %in% model$parms,
paste("-", k.candidate), "0")
- } else {
+ if(grepl("_free", from)) { # add transfer to bound compartment for SFORB
+ m[from,to] = paste(m[from,to], "-", paste("k", from, "bound", sep="_"))
+ }
+ if(grepl("_bound", from)) { # add backtransfer to free compartment for SFORB
+ m[from,to] = paste("- k", from, "free", sep="_")
+ }
+ m[from,to] = m[from,to]
+ } else { # off-diagonal elements
f.candidate = paste("f", from, "to", to, sep="_")
k.candidate = paste("k", from, to, sep="_")
k.candidate = sub("free.*bound", "free_bound", k.candidate)
@@ -1,4 +1,4 @@ -- Fix SFORB coefficient matrix by treating SFORB models with metabolites with ilr as well +- Adapt mkinplot function - Calculate confidence intervals for parameters assuming normal distribution - Calculate confidence intervals for DT50 and DT90 values when only one parameter is involved - Fix DT50 and DT90 calculation for SFORB_SFO |