aboutsummaryrefslogtreecommitdiff
path: root/docs/index.html
diff options
context:
space:
mode:
authorJohannes Ranke <jranke@uni-bremen.de>2017-11-16 14:55:06 +0100
committerJohannes Ranke <jranke@uni-bremen.de>2017-11-16 14:55:06 +0100
commit76a0aae725f4d603b3c8e8442bb67081891986b4 (patch)
tree1d4f29bd618c00997a9c1247691d9ad45528724e /docs/index.html
parent545d4bdfe1fc532f6d5d1718ee08444430d2976f (diff)
Add the code used for generating synthetic_data_for_UBA
Static documentation except articles rebuilt by pkgdown
Diffstat (limited to 'docs/index.html')
-rw-r--r--docs/index.html13
1 files changed, 2 insertions, 11 deletions
diff --git a/docs/index.html b/docs/index.html
index 1b4d89a6..f228bbe2 100644
--- a/docs/index.html
+++ b/docs/index.html
@@ -62,14 +62,7 @@
<a href="news/index.html">News</a>
</li>
</ul>
-<ul class="nav navbar-nav navbar-right">
-<li>
- <a href="http://github.com/jranke/mkin">
- <span class="fa fa-github fa-lg"></span>
-
- </a>
-</li>
- </ul>
+<ul class="nav navbar-nav navbar-right"></ul>
</div>
<!--/.nav-collapse -->
</div>
@@ -113,7 +106,7 @@
<li>Highly flexible model specification using <a href="http://kinfit.r-forge.r-project.org/mkin_static/reference/mkinmod.html"><code>mkinmod</code></a>, including equilibrium reactions and using the single first-order reversible binding (SFORB) model, which will automatically create two latent state variables for the observed variable.</li>
<li>As of version 0.9-39, fitting of several models to several datasets, optionally in parallel, is supported, see for example <a href="http://kinfit.r-forge.r-project.org/mkin_static/reference/plot.mmkin.html"><code>plot.mmkin</code></a>.</li>
<li>Model solution (forward modelling) in the function <a href="http://kinfit.r-forge.r-project.org/mkin_static/reference/mkinpredict.html"><code>mkinpredict</code></a> is performed either using the analytical solution for the case of parent only degradation, an eigenvalue based solution if only simple first-order (SFO) or SFORB kinetics are used in the model, or using a numeric solver from the <code>deSolve</code> package (default is <code>lsoda</code>).</li>
-<li>If a C compiler is installed, the kinetic models are compiled from automatically generated C code, see<br><a href="http://kinfit.r-forge.r-project.org/mkin_static/articles/compiled_models.html">vignette <code>compiled_models</code></a>. The autogeneration of C code was inspired by the <a href="https://github.com/karlines/ccSolve"><code>ccSolve</code></a> package. Thanks to Karline Soetaert for her work on that.</li>
+<li>If a C compiler is installed, the kinetic models are compiled from automatically generated C code, see <a href="http://kinfit.r-forge.r-project.org/mkin_static/articles/compiled_models.html">vignette <code>compiled_models</code></a>. The autogeneration of C code was inspired by the <a href="https://github.com/karlines/ccSolve"><code>ccSolve</code></a> package. Thanks to Karline Soetaert for her work on that.</li>
<li>By default, kinetic rate constants and kinetic formation fractions are transformed internally using <a href="http://kinfit.r-forge.r-project.org/mkin_static/reference/transform_odeparms.html"><code>transform_odeparms</code></a> so their estimators can more reasonably be expected to follow a normal distribution. This has the side effect that no constraints are needed in the optimisation. Thanks to René Lehmann for the nice cooperation on this, especially the isometric logration transformation that is now used for the formation fractions.</li>
<li>A side effect of this is that when parameter estimates are backtransformed to match the model definition, confidence intervals calculated from standard errors are also backtransformed to the correct scale, and will not include meaningless values like negative rate constants or formation fractions adding up to more than 1, which can not occur in a single experiment with a single defined radiolabel position.</li>
<li>The usual one-sided t-test for significant difference from zero is nevertheless shown based on estimators for the untransformed parameters.</li>
@@ -158,8 +151,6 @@
<ul class="list-unstyled">
<li>Download from CRAN at <br><a href="https://cran.r-project.org/package=mkin">https://​cran.r-project.org/​package=mkin</a>
</li>
-<li>Browse source code at <br><a href="http://github.com/jranke/mkin">http://​github.com/​jranke/​mkin</a>
-</li>
<li>Report a bug at <br><a href="http://github.com/jranke/mkin/issues">http://​github.com/​jranke/​mkin/​issues</a>
</li>
</ul>

Contact - Imprint