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authorJohannes Ranke <johannes.ranke@jrwb.de>2025-09-12 22:16:13 +0200
committerJohannes Ranke <johannes.ranke@jrwb.de>2025-09-12 22:16:13 +0200
commit17af45b984d348505527140470c7fff204748ea6 (patch)
tree4a7409236626c86e07746f7dfc736745f83a99d6 /docs/news
parent3ae975f6039da0edc3ae6298bcac388e7346e73f (diff)
Facilitate centering covariates
The motivation for this is to obtain confidence intervals for covariate dependent parameters that are valid for a median/mean value of the covariate. Implementation by adding an argument to the 'saem' function, and adapting the relevant functions working with 'saem' objects. Vignettes, the template and tests were updated to use the new functionality.
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1 files changed, 7 insertions, 3 deletions
diff --git a/docs/news/index.html b/docs/news/index.html
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+++ b/docs/news/index.html
@@ -1,5 +1,5 @@
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@@ -7,7 +7,7 @@
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- <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="Released version">1.2.10</small>
+ <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="Released version">1.2.11</small>
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<h2 class="pkg-version" data-toc-text="1.2.10" id="mkin-1210-unreleased">mkin 1.2.10 (unreleased)<a class="anchor" aria-label="anchor" href="#mkin-1210-unreleased"></a></h2>
<div class="section level3">
+<h3 id="new-features-1-2-10">New features<a class="anchor" aria-label="anchor" href="#new-features-1-2-10"></a></h3>
+<ul><li>‘R/{saem,endpoints,plot.mixed.mmkin}.R’: The function ‘saem()’ gains an argument ‘center_covariates’. The functions ‘parms’, ‘endpoints’ and ‘plot.mixed.mmkin’ were adapted, so the user can still specify covariate values on the original, uncentered scale even if a covariate is centered.</li>
+</ul></div>
+<div class="section level3">
<h3 id="bug-fixes-1-2-10">Bug fixes<a class="anchor" aria-label="anchor" href="#bug-fixes-1-2-10"></a></h3>
<ul><li><p>‘inst/rmarkdown/templates/hierarchical_kinetics/skeleton/skeleton.Rmd’: Make parent model selection more robust</p></li>
<li><p>‘R/mkinpredict.R’: Predictions and fits using solution type “deSolve” were previously incorrect in case there are no observed data for time zero (GitHub issue <a href="https://github.com/jranke/mkin/issues/16" class="external-link">#16</a>).</p></li>
@@ -670,7 +674,7 @@
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