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| -rw-r--r-- | NEWS.md | 1 |
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@@ -2,6 +2,7 @@ ## MAJOR CHANGES +- `summary.mkinfit()`: A one-sided t-test for significant difference of untransformed parameters from zero is now always shown, based on the assumption of normal distribution for estimators of all untransformed parameters. Use with caution, as this assumption is unrealistic e.g. for rate constants in these nonlinear kinetic models. - If a compiler (gcc) is installed, use a version of the differential equation model compiled from C code, which is a huge performance boost for models where only the deSolve method works. - `mkinmod()`: Create a list component $cf (of class CFuncList) in the list returned by mkinmod, if a version can be compiled from autogenerated C code (see above). - `mkinfit()`: Set the default `solution_type` to `deSolve` when a compiled version of the model is present, except when an analytical solution is possible. |